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Mum meets the stem cell donor who saved her four-year-old son’s life – Nottinghamshire Live

By adminFebruary 26, 2020Stem Cell Doctors

A mum has shared the emotional experience of meeting the stranger who saved her son's life.

Alfie Commons, now aged four, was just seven months old when he was diagnosed with leukaemia in 2016.

After three rounds of chemotherapy failed, Alfie received a life-saving bone marrow donation from a school teacher in Germany, who recently made the trip to the UK to meet him.

Alfie's mum, Lorna Commons, 40, of Toton has spoken about the experience in the hope it will encourage more people to sign up to become potential donors.

Looking back to the day of diagnosis, she said Alfie had been to his GP for a third time in February 2016 after suffering a cold since Christmas.

She said: "The GP told us to go to A&E for further tests as he was a little concerned.

"We got to Queen's Medical Centre in the morning and by early evening, we had the diagnosis; Alfie had infant acute lymphoblastic leukaemia (ALL)."

Ms Commons, who works in HR, added: "Even now, four years down the line, I still feel the emotions of that day. Nothing can prepare you."

The plan was to treat Alfie with chemotherapy, but after the first round failed, Ms Commons was told his only chance of survival was to get a bone marrow transplant.

The family was told Alfie was unlikely to leave hospital for the next six months.

She added: "Worse was to follow, his second course also failed and on the same day, we were told that Alfies nine-year-old brother, Billy, wasnt a bloodstemcellmatch for him either.

"The fear of losing Alfie was overwhelming, I felt helpless but I had to carry on for Alfies sake.

The transplant could not go ahead without the cancer being near enough eradicated and even when the good news came that a donor had been located, Alfie still had a mountain to climb.

After a third failed round of chemotherapy, Alfie was put on a trial immunotherapy drug as a '"last ditch attempt". Against all the odds, it worked.

"I think at that point all the doctors and nurses were preparing us for the worst. Your head has to go there," Ms Commons said.

"But then the cancer went, and it was enough to give us the bridge to getting the transplant done."

While the transplant was a success, Alfie suffered for months with Graft versus Host Disease (GvHD) on his skin and in his gut, which is the body's reaction to the new stem cells.

However, doctor's were encouraged the body was gradually accepting the cells and beginning to produce cells of their own.

On February 19, Alfie and his mum were able to meet the woman who saved his life after she made the 600-mile trip.

Christin Bouvier, 34, from Schwerin in Germany, was matched with Alfie after she registered in 2010 with DKMS, a charity dedicated to the fight against blood cancer.

The school teacher had been on the bloodstemcellregister for a number of years before she was contacted and tested as a match for Alfie.

Ms Bouvier said: When they told me that the recipient was a baby I just cried.

"Its a moment that is always with me and whenever I feel a bit down, I think back to it as it always brings me so much happiness!"

Ms Commons said she had been able to contact Ms Bouvier anonymously, as per UK law, but they were permitted to meet two years after the transplant.

Ms Bouvier added: It was always a dream to meet Lorna and Alfie and I never thought it would happen I was so delighted when Lorna invited me. I was very nervous but also very excited to meet them both in person.

"I knew the meeting would be one of those very special moments in my life."

Ms Commons feels the meeting has meant a new chapter has begun in both hers and Alfie's life and she is now focussed on the positives.

She added: "For something so small, there really is no greater gift than being a donor - I get to see my child grow up. To meet Christin, I was able to say 'this is what you've done'.

"We will be in each other's lives forever now - Alfie has her DNA in his blood. But Christin and I also share a special bond, we're just so similar and some people say we even look like sisters.

Alfie is such a special little boy and I truly believe that this story can make a real difference and save more lives.

"There is a match out there for everyone with blood cancer, people just need to come forward and register."

Anyone aged between 17-55 and in general good health can go on standby as a potential lifesaver.

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Mum meets the stem cell donor who saved her four-year-old son's life - Nottinghamshire Live

Global Genetic Testing Services Market is Expected to Reach USD 67.1 Billion by 2025 : Fior Markets – Yahoo Finance

By adminFebruary 26, 2020Gene Therapy Clinics

Global Genetic Testing Services Market by Test Type (Prenatal Testing, Newborn Screening, Predictive and Presymptomatic Testing), Application, Service Provider, Region, Global Industry Analysis, Market Size, Share, Growth, Trends, and Forecast 2018 to 2025

Newark, NJ, Feb. 25, 2020 (GLOBE NEWSWIRE) -- As per the report published by Fior Markets, theglobal genetic testing services market is expected to grow from USD 34.5 Billion in 2017 to USD 67.1 Billion by 2025 at a CAGR of 8.72% during the forecast period 2018-2025. Rising prevalence of genetic diseases, awareness among population, growing adoption of genetic testing services, and demand of genetic testing in developed countries, growing demand for personalized medicine, growing government initiatives and increased R&D activities in the genetic testing market are the factors that is driving genetic testing services market.

Genetic testing is used in the analysis of the changes in chromosomes, proteins, or genes caused by any suspected genetic condition or disease. It is also used in the diagnosis of cancer and plan the treatment. Several genetic tests are used such as new-born screening, prenatal testing, pre-implantation testing, carrier testing, etc. Numerous methods such as chromosomal method, molecular method and biochemical method are used for genetic testing. It is performed for the identification of risk factors, to screen the new-borns, and also in forensics. According to the report by WHO, sickle cell anaemia is one of the most common genetic disorders among people whose ancestors come from Sub-Saharan Africa, South America, Cuba, Central America, Saudi Arabia, India, and Mediterranean countries. Genetic tests in combination with other genomic technologies predict risk of an individual to a disease and also increase the opportunities for players in pharmaceutical industry to grow. For instance, and provides genetic makeup tests to the consumers. Company also recommends genetic counsellors based on results to help the consumers about the better testing of genes, and the inherited diseases.

Advancements in genetic testing technologies, rising cases of genetic diseases and growing awareness are driving the testing market. In addition, emerging markets hold great potential for growth of due to growing awareness and increase in patients in these regions. High cost and lack of experienced professionals are some of the factors restraining the growth of the market. However, Shift from clinical science to bioinformatics is also leading to high rate of adoption of genetic testing technology, which in turn is augmenting the growth of the market in coming years.

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Key players operating in the global genetic testing services market include Laboratory Corporation of America Holdings, Genomic Health, Inc., NeoGenomics Laboratories, Inc., Quest Diagnostics, Eurofins Scientific, Ambry Genetics, Hoffmann-La Roche Ltd, Illumina, Inc., CENTOGENE AG, 23andMe, Sequenom, GeneDx, Abbott, Cepheid Inc., ELITech Group, Verinata Health, Inc and others. Top players of the market are making efforts in R&D to increase their footprint in the market.

The predictive & presymptomatic testing is dominating the segment and was valued around USD 12.17 billion in 2017

The test type segment includes prenatal testing, newborn screening, predictive and presymptomatic testing, pharmacogenomic testing. The predictive & presymptomatic testing is dominating the segment and was valued around USD 12.17 billion in 2017. Detection of diseases at early stage minimizes the severity of diseases leading to reduced mortality rate. Increasing prevalence of chronic diseases around the world is expected to augment the segment growth over the forecast period.

The oncology segment dominated the application segment and is expected to register the highest CAGR of 10.07% in the forecast period

The application segment is divided into segments such as oncology, infectious diseases and autoimmune diseases. The oncology segment dominated the application segment and is expected to register the highest CAGR of 10.07% in the forecast period. Timely diagnosis save lives and reduce the number of deaths. According to, The Institute for Health Metrics and Evaluation (IHME), around 8.9 million cancer deaths were recorded in 2016 caused by inheriting genetic mutation. Rising prevalence of various types of cancer such as prostate cancer, breast cancer and lung cancer coupled with increasing awareness pertaining to early detection of cancer are expected to stimulate the growth of the market.

Story continues

The hospital-based laboratories segment is dominating the genetic testing services market and held the largest market share of 38.21% in 2017

The service provider segment is classified into hospital-based laboratories, diagnostic laboratories and specialty clinics. The hospital-based laboratories segment is dominating the genetic testing services market and held the largest market share of 38.21% in 2017. Advanced infrastructure and increasing number of hospitals in developing economies are driving the growth of the market.

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Regional Segment Analysis of the Genetic Testing Services Market

The regions analysed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. North America region dominated the global genetic testing services market with the largest share and was valued around USD 15.180 Billion in 2017 where as Asia Pacific region is the fastest growing region in the market. North America region is dominating the market due to developed infrastructure, increase in health care investments and presence of large number of academic and research institutes are key factors leading to the growth of the market. Asia Pacific is anticipated to register highest growth in the forecast period. Increase in the prevalence of infectious disease, increasing awareness about the advantages of predictive testing, and rise in the adoption of advanced technology for clinical applications are some of the major factors offering growth opportunities to the genetic testing services market.

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The global genetic testing services market is analysed on the basis of value (USD Billion). All the segments have been analyzed on global, regional and country basis. The study includes the analysis of more than 30 countries for each segment. The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The study includes porters five forces model, attractiveness analysis, raw material analysis, supply, demand analysis, competitor position grid analysis, distribution and marketing channels analysis.

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Global Genetic Testing Services Market is Expected to Reach USD 67.1 Billion by 2025 : Fior Markets - Yahoo Finance

New study identifies trigger that turns dormant cancer stem cells into active ones – PR Web

By adminFebruary 26, 2020Induced Pluripotent Stem Cells

DURHAM, N.C. (PRWEB) February 26, 2020

A new study released today in STEM CELLS identifies, for the first time, two morphologically and functionally different types of cancer stem cells found in cervical cancer. Of the two types, one exhibits an overexpression of cPLA2, a key enzyme that triggers the transformation of dormant cancer stem cells into active ones, resulting in cervical cancer metastasis and recurrence. The information in this study could lead to new targets for treatments to halt tumor recurrence and metastatic spread. Also, it might accelerate the development of combination therapies.

The current standard of treatments for cervical cancer the second leading cause of cancer death in young women worldwide is radiotherapy and chemotherapy. However, the cancers resistance to chemotherapy and radiation, combined with a tendency to metastasis in the lymph nodes or recur in the pelvis, leaves doctors searching for more effective treatments.

Cervical cancer stem cells (CCSCs) are considered the major culprit behind the cancers ability to overcome these treatments. At the same time, a majority of cancer stem-like cells or tumor-initiating cells remain dormant. It takes a change in their microenvironment to spur them to metastasize.

The mechanisms responsible for this must be identified to design more suitable therapies for the different subpopulations of cancer stem cells (CSCs) in various tissue-specific cancers, said Hua Guo, Ph.D., who headed up the investigation along with Yuchao He, Ph.D. The two are colleagues at Tianjin Medical University Cancer Institute and Hospital. Researchers at Tianjin University of Traditional Chinese Medicine and at the Center for Translational Cancer Research, Peking University First Hospital, also participated in the study.

Although several cell surface antigens have been identified in CCSCs, these markers vary among tumors because of CSC heterogeneity. However, whether these markers specifically distinguish CCSCs with different functions is unclear. The study published in STEM CELLS sought to resolve this question. And in fact, its findings demonstrate that CCSCs exist in two biologically distinct phenotypes, characterized by different levels of cPLA2 expression.

Our study showed for the first time that overexpression of cPLA2 results in a phenotype associated with mesenchymal traits, including increased invasive and migration abilities. On the other hand, CCSCs with cPLA2 downregulation show dormant epithelial characteristics, said Dr. Guo. In addition, cPLA2 regulates the reversible transition between mesenchymal and epithelial CCSC states through PKC, an atypical protein that governs cancer cell state changes.

Dr. He added, Now that we know cPLA2 triggers this transformation, we believe that cPLA2 might be an attractive therapeutic target for eradicating different states of CCSCs to eliminate tumors more effectively.

The novel study by Dr. Guo and team is of very high importance in understanding the transition between dormant cancer stem cells, which evade chemotherapy and radiation treatments, and actively dividing cells which can be better targeted, said Dr. Jan Nolta, Editor-in-Chief of STEM CELLS. I applaud the group for this important discovery which will help researchers develop better treatments for cervical cancer.

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The full article, cPLA2 reversibly regulate different subsets of cancer stem cells transformation in cervical cancer, can be accessed at https://stemcellsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/stem.3157.

Figure Caption: This study revealed that there are two morphologically and functionally distinct cancer stem cell populations regulated by cPLA2 in cervical cancer. cPLA2 might be a unique marker to identify different cancer stem cell populations and trigger quiescent epithelial cancer stem cells transform to invasive mesenchymal states. Overexpression of cPLA2 resulted in a CD44+CD24- phenotype with mesenchymal traits, whereas cervical cancer stem cells (CCSCs) with cPLA2 downregulation expressed CD133 and showed epithelial characteristics. cPLA2, as a key role to reversely regulate CCSCs states and EMT, might provide innovative therapeutic strategies intended to halt tumor recurrence and metastasis.

About the Journal: STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. The journal covers all aspects of stem cells: embryonic stem cells/induced pluripotent stem cells; tissue-specific stem cells; cancer stem cells; the stem cell niche; stem cell epigenetics, genomics and proteomics; and translational and clinical research. STEM CELLS is co-published by AlphaMed Press and Wiley.

About AlphaMed Press: Established in 1983, AlphaMed Press with offices in Durham, NC, San Francisco, CA, and Belfast, Northern Ireland, publishes three internationally renowned peer-reviewed journals with globally recognized editorial boards dedicated to advancing knowledge and education in their focused disciplines. STEM CELLS (http://www.StemCells.com) is the world's first journal devoted to this fast paced field of research. THE ONCOLOGIST (http://www.TheOncologist.com) is devoted to community and hospital-based oncologists and physicians entrusted with cancer patient care. STEM CELLS TRANSLATIONAL MEDICINE (http://www.StemCellsTM.com) is dedicated to significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices.

About Wiley: Wiley, a global company, helps people and organizations develop the skills and knowledge they need to succeed. Our online scientific, technical, medical and scholarly journals, combined with our digital learning, assessment and certification solutions, help universities, learned societies, businesses, governments and individuals increase the academic and professional impact of their work. For more than 200 years, we have delivered consistent performance to our stakeholders. The company's website can be accessed at http://www.wiley.com.

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New study identifies trigger that turns dormant cancer stem cells into active ones - PR Web

Induced Pluripotent Stem Cells (iPSCs) Market in 2020: Global Industry Size, Demand, Growth & Development, Trends, Insights and Forecast until…

By adminFebruary 25, 2020Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells (iPSCs) Market Research Report is provided on past, current and anticipated market situations, market drivers, trends driving it, and the challenges faced by the market which will help in deciding corporate strategy, product strategy, marketing strategy and sales strategy. The report also contains a comprehensive market and vendor landscape in addition to a SWOT analysis of the key vendors.

Induced Pluripotent Stem Cells (iPSCs) Market Report is analyzed for major factors such as consumer needs and changes observed in them over time, market sales in terms of value and volume, emerging opportunities, market growth trends, factors driving this market, threats associated with them and market performance of key vendors along with key regions.

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Global Induced Pluripotent Stem Cells (iPSCs) Market Segment by Type, covers

Global Induced Pluripotent Stem Cells (iPSCs) Market Segment by Applications, can be divided into

Global Induced Pluripotent Stem Cells (iPSCs) Market Segment by Manufacturers, this report covers:

Hanssem,Aria Furniture,EMONS,Muse Furniture,Man Wah Holdings,La-Z-Boy,Natuzzi Editions,Ashley Furniture,Ekornes

Table of Contents1 Induced Pluripotent Stem Cells (iPSCs) Market Overview1.1 Product Overview and Scope of Induced Pluripotent Stem Cells (iPSCs)1.2 Induced Pluripotent Stem Cells (iPSCs) Segment by Type1.2.1 Global Induced Pluripotent Stem Cells (iPSCs) Production Growth Rate Comparison by Type 2020 VS 20261.2.2 Compact Type Induced Pluripotent Stem Cells (iPSCs)1.2.3 Standard Type Induced Pluripotent Stem Cells (iPSCs)1.3 Induced Pluripotent Stem Cells (iPSCs) Segment by Application1.3.1 Induced Pluripotent Stem Cells (iPSCs) Consumption Comparison by Application: 2020 VS 20261.4 Global Induced Pluripotent Stem Cells (iPSCs) Market by Region1.4.1 Global Induced Pluripotent Stem Cells (iPSCs) Market Size Estimates and Forecasts by Region: 2020 VS 20261.4.2 North America Estimates and Forecasts (2015-2026)1.4.3 Europe Estimates and Forecasts (2015-2026)1.4.4 China Estimates and Forecasts (2015-2026)1.4.5 Japan Estimates and Forecasts (2015-2026)1.5 Global Induced Pluripotent Stem Cells (iPSCs) Growth Prospects1.5.1 Global Induced Pluripotent Stem Cells (iPSCs) Revenue Estimates and Forecasts (2015-2026)1.5.2 Global Induced Pluripotent Stem Cells (iPSCs) Production Capacity Estimates and Forecasts (2015-2026)1.5.3 Global Induced Pluripotent Stem Cells (iPSCs) Production Estimates and Forecasts (2015-2026)2 Market Competition by Manufacturers2.1 Global Induced Pluripotent Stem Cells (iPSCs) Production Capacity Market Share by Manufacturers (2015-2020)2.2 Global Induced Pluripotent Stem Cells (iPSCs) Revenue Share by Manufacturers (2015-2020)2.3 Market Share by Company Type (Tier 1, Tier 2 and Tier 3)2.4 Global Induced Pluripotent Stem Cells (iPSCs) Average Price by Manufacturers (2015-2020)2.5 Manufacturers Induced Pluripotent Stem Cells (iPSCs) Production Sites, Area Served, Product Types2.6 Induced Pluripotent Stem Cells (iPSCs) Market Competitive Situation and Trends2.6.1 Induced Pluripotent Stem Cells (iPSCs) Market Concentration Rate2.6.2 Global Top 3 and Top 5 Players Market Share by Revenue2.6.3 Mergers & Acquisitions, Expansion3 Production Capacity by Region3.1 Global Production Capacity of Induced Pluripotent Stem Cells (iPSCs) Market Share by Regions (2015-2020)3.2 Global Induced Pluripotent Stem Cells (iPSCs) Revenue Market Share by Regions (2015-2020)3.3 Global Induced Pluripotent Stem Cells (iPSCs) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.4 North America Induced Pluripotent Stem Cells (iPSCs) Production3.4.1 North America Induced Pluripotent Stem Cells (iPSCs) Production Growth Rate (2015-2020)3.4.2 North America Induced Pluripotent Stem Cells (iPSCs) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.5 Europe Induced Pluripotent Stem Cells (iPSCs) Production3.5.1 Europe Induced Pluripotent Stem Cells (iPSCs) Production Growth Rate (2015-2020)3.5.2 Europe Induced Pluripotent Stem Cells (iPSCs) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.6 China Induced Pluripotent Stem Cells (iPSCs) Production3.6.1 China Induced Pluripotent Stem Cells (iPSCs) Production Growth Rate (2015-2020)3.6.2 China Induced Pluripotent Stem Cells (iPSCs) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.7 Japan Induced Pluripotent Stem Cells (iPSCs) Production3.7.1 Japan Induced Pluripotent Stem Cells (iPSCs) Production Growth Rate (2015-2020)3.7.2 Japan Induced Pluripotent Stem Cells (iPSCs) Production Capacity, Revenue, Price and Gross Margin (2015-2020)4 Global Induced Pluripotent Stem Cells (iPSCs) Consumption by Regions4.1 Global Induced Pluripotent Stem Cells (iPSCs) Consumption by Regions4.1.1 Global Induced Pluripotent Stem Cells (iPSCs) Consumption by Region4.1.2 Global Induced Pluripotent Stem Cells (iPSCs) Consumption Market Share by Region5 Production, Revenue, Price Trend by Type5.1 Global Induced Pluripotent Stem Cells (iPSCs) Production Market Share by Type (2015-2020)5.2 Global Induced Pluripotent Stem Cells (iPSCs) Revenue Market Share by Type (2015-2020)5.3 Global Induced Pluripotent Stem Cells (iPSCs) Price by Type (2015-2020)5.4 Global Induced Pluripotent Stem Cells (iPSCs) Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End6 Global Induced Pluripotent Stem Cells (iPSCs) Market Analysis by Application6.1 Global Induced Pluripotent Stem Cells (iPSCs) Consumption Market Share by Application (2015-2020)6.2 Global Induced Pluripotent Stem Cells (iPSCs) Consumption Growth Rate by Application (2015-2020)7 Company Profiles and Key Figures in Induced Pluripotent Stem Cells (iPSCs) Business7.2.4 Main Business and Markets Served8 Induced Pluripotent Stem Cells (iPSCs) Manufacturing Cost Analysis8.1 Induced Pluripotent Stem Cells (iPSCs) Key Raw Materials Analysis8.1.1 Key Raw Materials8.1.2 Key Raw Materials Price Trend8.1.3 Key Suppliers of Raw Materials8.2 Proportion of Manufacturing Cost Structure8.3 Manufacturing Process Analysis of Induced Pluripotent Stem Cells (iPSCs)8.4 Induced Pluripotent Stem Cells (iPSCs) Industrial Chain Analysis9 Marketing Channel, Distributors and Customers9.1 Marketing Channel9.2 Induced Pluripotent Stem Cells (iPSCs) Distributors List9.3 Induced Pluripotent Stem Cells (iPSCs) Customers10 Market Dynamics10.1 Market Trends10.2 Opportunities and Drivers10.3 Challenges10.4 Porters Five Forces Analysis11 Production and Supply Forecast11.1 Global Forecasted Production of Induced Pluripotent Stem Cells (iPSCs) (2021-2026)11.2 Global Forecasted Revenue of Induced Pluripotent Stem Cells (iPSCs) (2021-2026)11.3 Global Forecasted Price of Induced Pluripotent Stem Cells (iPSCs) (2021-2026)11.4 Global Induced Pluripotent Stem Cells (iPSCs) Production Forecast by Regions (2021-2026)11.4.1 North America Induced Pluripotent Stem Cells (iPSCs) Production, Revenue Forecast (2021-2026)11.4.2 Europe Induced Pluripotent Stem Cells (iPSCs) Production, Revenue Forecast (2021-2026)11.4.3 China Induced Pluripotent Stem Cells (iPSCs) Production, Revenue Forecast (2021-2026)11.4.4 Japan Induced Pluripotent Stem Cells (iPSCs) Production, Revenue Forecast (2021-2026)12 Consumption and Demand Fprecast12.1 Global Forecasted and Consumption Demand Analysis of Induced Pluripotent Stem Cells (iPSCs)12.2 North America Forecasted Consumption of Induced Pluripotent Stem Cells (iPSCs) by Country12.3 Europe Market Forecasted Consumption of Induced Pluripotent Stem Cells (iPSCs) by Country12.4 Asia Pacific Market Forecasted Consumption of Induced Pluripotent Stem Cells (iPSCs) by Regions12.5 Latin America Forecasted Consumption of Induced Pluripotent Stem Cells (iPSCs)13 Forecast by Type and by Application (2021-2026)13.1 Global Production, Revenue and Price Forecast by Type (2021-2026)13.1.1 Global Forecasted Production of Induced Pluripotent Stem Cells (iPSCs) by Type (2021-2026)13.1.2 Global Forecasted Revenue of Induced Pluripotent Stem Cells (iPSCs) by Type (2021-2026)13.1.2 Global Forecasted Price of Induced Pluripotent Stem Cells (iPSCs) by Type (2021-2026)13.2 Global Forecasted Consumption of Induced Pluripotent Stem Cells (iPSCs) by Application (2021-2026)14 Reseach Finding and Conclusion15 Methodology and Data Source15.1 Methodology/Research Approach15.1.1 Research Programs/Design15.1.2 Market Size Estimation15.1.3 Market Breakdown and Data Triangulation15.2 Data Source15.2.1 Secondary Sources15.2.2 Primary Sources15.3 Author List15.4 Disclaimer. And More

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Induced Pluripotent Stem Cells (iPSCs) Market in 2020: Global Industry Size, Demand, Growth & Development, Trends, Insights and Forecast until...

DDP and Austin Aries Reportedly Pitching Stem Cell Venture to AEW | 411MANIA – 411mania.com

By adminFebruary 25, 2020Stem Cell Clinic

Diamond Dallas Page and Austin Aries had business at last nights AEW according to a new report, but not the kind you might immediately think of. As noted last night, DDP and Aries were seen entering the area at last nights episode in Atlanta.

According to BodySlam.net, the two were there because theyre part of a stem cell treatment venture. They were there to pitch the idea to AEW in hopes that the company would buy into the venture. Stem Cell therapy has become increasingly popular among wrestlers to deal with injury issues over the past several years, and Aries is one of several people (along with Ken Shamrock, Rob Van Dam and others) to make regular mention of the BioXcellerator stem cell therapy clinic.

DDP has been a semi-regular on AEW, making several appearances on Dynamite over the past few months.

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DDP and Austin Aries Reportedly Pitching Stem Cell Venture to AEW | 411MANIA - 411mania.com

Hyperbaric chamber therapy: Im under a lot of pressure and I love it! – The Guardian

By adminFebruary 25, 2020Stem Cell Clinic

I wonder what the pedalo does as I slip into a waffle robe Im at Bellecell, a central London molecular-wellness clinic that offers hyper-personalised science-based solutions to health this place could be a Bond villains laboratory on the moon.

I am standing in a hushed, blue-lit underground brick tunnel with Kubrick-white furnishings and so many fascinating toys: EMS suits, laser IVs, and what looks like an exercise bike built into a love boat, with a vacuum for your legs.

As distracting as these things are, I am here to try something specific: a hyperbaric oxygen chamber. I am fascinated by these things. Culturally, they have long been signifiers of megalomania, detachment and anxiety. Michael Jackson had one in his house, which isnt a great recommendation. The Olympian swimmer Michael Phelps is another fan. But what do these chambers actually do? Do you have to be called Michael to use one?

I climb into a plastic body bag in my hospital booties. Hyperbaric oxygen therapy involves breathing pure oxygen in a pressurised environment. The structure is a semi-circular cage with comfortable bedding, surrounded by thick plastic walls. Once I am inside, a technician inflates the bag. I am basically inside a balloon, which will be maintained at constant pressure, as I breathe 100% oxygen through a mask.

Hyperbaric chambers are mostly used to treat gas gangrene, carbon monoxide poisoning and the bends, while the medical uses of oxygen include wound-healing and reducing the risk of infection. Many people report feeling energised afterwards. I have some oral swelling following dental work, and am interested to see if that goes down.

For some, the close confinement and constant sound of pressurisation will be a recipe for a panic attack. For me, it is heaven. I am what you might call a claustrophile. I have always loved climbing into cupboards and corners, making dens and closing a door on the world. I fantasise about Japanese capsule hotels. Now, I lie and watch a zip close above me. There is a hissing noise. I adjust my oxygen mask and observe star-headed thumb screws being turned to calibrate the pressure. The gauge crawls upwards, my ears are getting stuffy. I swallow as it hits 4psi, equivalent to a depth of nine feet under water. Gazing at ambient blue through a hatch to the outside world, I imagine Im much deeper, packed into a nuclear missile on the undercarriage of a submarine. I am in my happy place.

The use of oxygen for performance-enhancement is mostly misunderstood. The effects of inhaling it are extremely short-lived. Athletes are often seen huffing cans of oxygen at the touchline, but science indicates that this is a mostly meaningless activity. Pressure makes all the difference. Under pressure, oxygen is dissolved in larger quantities in the blood plasma itself, not just the red blood cells. That means a much higher amount of the gas is transported into tissues that need it for healing, in theory mobilising stem cell release to repair the body quickly. It is definitely promising; the catch is, you would probably need a few treatments to see the benefit. At 160 an hour, post-workout muscle soreness probably isnt reason enough.

I thoroughly enjoy the experience for its own sake. Lulled by the pressure and soft lighting outside, I fall into a deep, restorative nap. After an hour, I emerge as wobbly as a newborn. I dont feel supercharged, admittedly. I feel drowsy, and absolutely starving. Im assured this is normal. I do feel astonishingly relaxed, though. The swelling inside my mouth reduces significantly over the next day, too, for which I can probably thank the chamber.

I would totally have one of these in my house. I miss the missile, but cant afford to go back. Instead, Im cursed to walk these normobaric streets, breathing 21% oxygen like everyone else, dreaming of when I had less freedom to move.

Walter White, eat your heart out Could I recreate the effect with hydrogen peroxide, bakers yeast and a tarp over the bath?

Wellness or hellness? Airs and graces. 5/5

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Hyperbaric chamber therapy: Im under a lot of pressure and I love it! - The Guardian

Why Austin Aries and Raven Were At AEW Dynamite – PWMania

By adminFebruary 25, 2020Stem Cell Clinic

Mike Johnson of PWInsider.com noted the following regarding why Raven was sitting in the crowd during AEW Dynamite:

The Raven appearance looks to have been a red herring to make viewers think he is the exalted one when there are plans to go in another direction.

It appears that Austin Aries was backstage at AEW Dynamite in regards to Bioxcellerator, a stem cell therapy clinic that he serves as the Director of Athletic Performance Division. Aries gave the following statement to Bodyslam.net:

I did have meetings about partnerships and collaborations with both DDP and DDPY Brand as well as AEW.

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BIG ANNOUNCEMENT!!! . Many of you know that I went down to Medellin, Colombia in December for @bioxcellerator_ #stemcelltherapy, and now after a couple months, my neck and lower back feel really good. I was honestly so impressed with the entire @bioxcellerator_ operation. So much so, that upon returning I had conversations about joining the @bioxcellerator_ team in some capacity. . With that, I am EXTREMELY EXCITED TO ANNOUNCE that I have officially joined BioXcellerator as Director Of Athletic Performance Division. My role will be to continue connecting high level athletes, entertainers and influencers with all the amazing benefits of @bioxcellerator_ #stemcelltherapy. As someone whose passion is helping people, I couldnt pass up the opportunity to be a part of this company that is changing lives with their cutting edge #stemcelltherapy. . So, anyone whos been thinking about, or interested in finding out more about BioXcellerator stem cell therapy, Im your guy! Please DM or email me at Austin@BioXcellerator.com. Heres to all our improved health and happiness in 2020 and beyond! . . #bioxcellerator #bioxmen #bioxwomen #stemcell #stemcells #stemcelltherapy #medellin #colombia

A post shared by Austin Aries (@austinhealyaries) on Feb 17, 2020 at 8:49am PST

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Why Austin Aries and Raven Were At AEW Dynamite - PWMania

Bit Bio Secures Distribution Agreement with Abcam to Democratize Access to Human Cells for Global Life Science Research – BioSpace

By adminFebruary 25, 2020Stell Cell Research

CAMBRIDGE, England, Feb. 25, 2020 /PRNewswire/ --Bit Bio announces agreement with Abcam, a global innovator in life science reagents and tools, to make Bit Bio's iPSC derived functional human cells widely available to the global life science community. Over the course of the next two years this new partnership will provide an increasing range of highly defined, scalable and consistent human cells for research and high-throughput screening applications. The first product available are brain cells (ioNEURONS/glutTM, glutamatergic neurons) serving the neuroscience community.

Access to human cells is a significant bottleneck in the field of medical research and drug development. Human cells differ from animal models, and therefore research using animal models often does not translate into clinical applications.

Bit Bio is commercializing opti-oxTM, a precise reprogramming proprietary technology platform that enables uniquely efficient and consistent production of human cells for use in research, drug discovery, and cell therapy.

"Bit Bio's goal is to develop a scalable technology platform capable of producing consistent batches of every human cell type," said Bit Bio CEO Mark Kotter, a neurosurgeon at Cambridge University, and stem cell biologist. "This agreement will accelerate our mission of putting highly defined human cells in the hands of the researchers who need them to pursue their life-saving work."

"Supporting enhanced access to complementary technologies that have the potential to improve and accelerate research is part of our growth strategy," said John Baker, Senior Vice President Product Portfolio and Innovation at Abcam. "Our industry expertise, and co-location in major biotechnology hubs throughout the world, enables our partners to rapidly put their innovations into the hands of the global research community, helping advance the understanding of biology and cause of disease to enable new treatments and improved health outcomes."

Bit Bio's breakthrough technology has been successfully employed to reprogram stem cells into functional neurons on a scalable and consistent basis. The proprietary approach ensures batch to batch reproducibility and unprecedented purity compared to current technologies and yields fully differentiated neurons within days. The protocol is also universally applicable, from small-scale laboratory research projects to high throughput screens in pharmaceutical R&D laboratories.

Bit Bio's human-induced glutamatergic neurons are a highly defined and consistent human model for the study of neurological physiology and disease, including neurodegeneration, and are available from the Abcam website.

"At Bit Bio we believe that world-wide access to our iPSC derived cells will drive human translational experiments and ultimately help to fuel the next generation of medicine," said Bit Bio Chief Business Officer Paul Morrill. "Abcam's reputation as a disruptive innovator in the field of biological reagents and dedicated global commercialization infrastructure make them the ideal partner. In line with our core value of democratizing access to human cells for research and drug development, our ioNEURONS/glut are offered at a highly competitive price point."

About Bit Bio

Bit Bio, the cell coding company, is based in Cambridge, UK. Bit Bio's team includes world leaders in stem cell biology, cellular reprogramming and cell therapy who are harnessing the power of synthetic biology to tackle the problem of inconsistency in the production of human cells. Bit Bio is developing opti-oxTM, a proprietary technology platform capable of producing any human cell for research, drug discovery and cell therapy.

We areintroducing ioNEURONS/glutTM,human-induced glutamatergic neuronscells, providing a high-quality human model for research, drug development and high-throughput screening.ioNEURONS/glut cells have been reprogrammed from human induced pluripotent stem cells (hiPSC) using a precise reprogramming technology.

To find out more, please visit http://www.bit.bio

Bit Bio press contact:Dr Farah Patell-Socha, press@bit.bio

About AbcamAs a global life sciences company, Abcam identifies, develops, and distributes high-quality biological reagents and tools that are crucial to research, drug discovery and diagnostics. Working across the industry, the Company supports life scientists to achieve their mission, faster. Abcam partners with life science organisations to co-create novel binders for use in drug discovery,in vitrodiagnostics and therapeutics, driven by the Company's proprietary discovery platforms and world-leading, antibody expertise.

By constantly innovating its binders and assays, Abcam is helping advance the global understanding of biology and causes of disease, which enables new treatments and improved health. The Company's pioneering data-sharing approach gives scientists increased confidence in their results by providing validation, user comments and peer-reviewed citations for its 110,000 products. With eleven sites globally, many of Abcam's 1,100 strong team are located in the world's leading life science research hubs, complementing a global network of services and support.

To find out more, please visitwww.abcam.comandwww.abcamplc.com.

Abcam press contact:Dr Lynne Trowbridge, lynne.trowbridge@abcam.com

View original content:http://www.prnewswire.com/news-releases/bit-bio-secures-distribution-agreement-with-abcam-to-democratize-access-to-human-cells-for-global-life-science-research-301010337.html

SOURCE Bit Bio

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Bit Bio Secures Distribution Agreement with Abcam to Democratize Access to Human Cells for Global Life Science Research - BioSpace

Stem Cell and Regenerative Therapy Market To Witness High Exponential Growth By 2020 2026 – Galus Australis

By adminFebruary 25, 2020Stell Cell Research

This Stem Cell and Regenerative Therapy Market research report is focused at providing its reader with all the necessary details that can help them make necessary business decisions. It provides wholesome information that is necessary to understand the market inside-out.

ReportsnReports has recently added a new research report to its expanding repository. The research report, titled Stem Cell and Regenerative Therapy Market, mainly includes a detailed segmentation of this sector, which is expected to generate massive returns by the end of the forecast period, thus showing an appreciable rate of growth over the coming years on an annual basis. The research study also looks specifically at the need for Stem Cell and Regenerative Therapy Market.

Report Scope:

The scope of this report is broad and covers various type of product available in the stem cell and regenerative medicines market and potential application sectors across various industries. The current report offers a detailed analysis of the stem cell and regenerative medicines market.

The report highlights the current and future market potential of stem cell and regenerative medicines and provides a detailed analysis of the competitive environment, recent development, merger and acquisition, drivers, restraints, and technology background in the market. The report also covers market projections through 2024.

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The report details market shares of stem cell and regenerative medicines based on products, application, and geography. Based on product the market is segmented into therapeutic products, cell banking, tools and reagents. The therapeutics products segments include cell therapy, tissue engineering and gene therapy. By application, the market is segmented into oncology, cardiovascular disorders, dermatology, orthopedic applications, central nervous system disorders, diabetes, others

The market is segmented by geography into the following regions: North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. The report presents detailed analyses of major countries such as the U.S., Canada, Mexico, Germany, the U.K. France, Japan, China and India. For market estimates, data is provided for 2018 as the base year, with forecasts for 2019 through 2024. Estimated values are based on product manufacturers total revenues. Projected and forecasted revenue values are in constant U.S. dollars, unadjusted for inflation.

Report Includes:

28 data tables An overview of global markets for stem cell and regenerative medicines Analyses of global market trends, with data from 2018, estimates for 2019, and projections of compound annual growth rates (CAGRs) through 2024 Details of historic background and description of embryonic and adult stem cells Information on stem cell banking and stem cell research A look at the growing research & development activities in regenerative medicine Coverage of ethical issues in stem cell research & regulatory constraints on biopharmaceuticals Comprehensive company profiles of key players in the market, including Aldagen Inc., Caladrius Biosciences Inc., Daiichi Sankyo Co. Ltd., Gamida Cell Ltd. and Novartis AG

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Summary:

The global market for stem cell and regenerative medicines was valued at REDACTED billion in 2018. The market is expected to grow at a compound annual growth rate (CAGR) of REDACTED to reach approximately REDACTED billion by 2024. Growth of the global market is attributed to the factors such as growingprevalence of cancer, technological advancement in product, growing adoption of novel therapeuticssuch as cell therapy, gene therapy in treatment of chronic diseases and increasing investment fromprivate players in cell-based therapies.

In the global market, North America held the highest market share in 2018. The Asia-Pacific region is anticipated to grow at the highest CAGR during the forecast period. The growing government funding for regenerative medicines in research institutes along with the growing number of clinical trials based on cell-based therapy and investment in R&D activities is expected to supplement the growth of the stem cell and regenerative market in Asia-Pacific region during the forecast period.

Reasons for Doing This Study

Global stem cell and regenerative medicines market comprises of various products for novel therapeutics that are adopted across various applications. New advancement and product launches have influenced the stem cell and regenerative medicines market and it is expected to grow in the near future. The biopharmaceutical companies are investing significantly in cell-based therapeutics. The government organizations are funding research and development activities related to stem cell research. These factors are impacting the stem cell and regenerative medicines market positively and augmenting the demand of stem cell and regenerative therapy among different application segments. The market is impacted through adoption of stem cell therapy. The key players in the market are investing in development of innovative products. The stem cell therapy market is likely to grow during the forecast period owing to growing investment from private companies, increasing in regulatory approval of stem cell-based therapeutics for treatment of chronic diseases and growth in commercial applications of regenerative medicine.

Products based on stem cells do not yet form an established market, but unlike some other potential applications of bioscience, stem cell technology has already produced many significant products in important therapeutic areas. The potential scope of the stem cell market is now becoming clear, and it is appropriate to review the technology, see its current practical applications, evaluate the participating companies and look to its future.

The report provides the reader with a background on stem cell and regenerative therapy, analyzes the current factors influencing the market, provides decision-makers the tools that inform decisions about expansion and penetration in this market.

Access Full Report athttps://www.reportsnreports.com/purchase.aspx?name=2351731

Recent Industry Trend:

The report contains the profiles of various prominent players in the Global Stem Cell and Regenerative Therapy Market. Different strategies implemented by these vendors have been analyzed and studied in order to gain a competitive edge, create unique product portfolios and increase their market share. The study also sheds light on major global industry vendors. Such essential vendors consist of both new and well-known players. In addition, the business report contains important data relating to the launch of new products on the market, specific licenses, domestic scenarios and the strategies of the organization implemented on the market.

Scope of the Report:

Through following the Stem Cell and Regenerative Therapy Market through depth, the readers should find this study very helpful. The aspects and details are depicted by charts, bar graphs, pie diagrams, and other visual representations in theStem Cell and Regenerative Therapy Market study. This intensifies the representation of the pictures and also helps to improve the facts of the Stem Cell and Regenerative Therapy Market industry. At a substantial CAGR, the Stem Cell and Regenerative Therapy Market is likely to grow. Stem Cell and Regenerative Therapy Market reports main objective is to guide the user to understand the market in terms of its definition, classification, industry potential, the latest trends, and the challenges facing the Stem Cell and Regenerative Therapy Market.

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Stem Cell and Regenerative Therapy Market To Witness High Exponential Growth By 2020 2026 - Galus Australis

Hematopoietic Stem Cell Transplantation (HSCT) Market Trend Forecast And Growth Drivers by 2026 – News Parents

By adminFebruary 25, 2020Stell Cell Research

The Hematopoietic Stem Cell Transplantation (HSCT) Market is a broad research dependent on industry, which examines the escalated structure of the present market all around the world. Planned by the sufficient orderly system, for example, SWOT investigation, the Hematopoietic Stem Cell Transplantation (HSCT) market report demonstrates an aggregate appraisal of overall business overview.

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Hematopoietic Stem Cell Transplantation (HSCT) Marketreport would come in handy to understand your competitors and give you an insight into sales, volumes, revenues in the Hematopoietic Stem Cell Transplantation (HSCT) industry, assists in making strategic decisions. The report contains proven analysis by regions.It reduces the risks involved in making decisions as well as strategies for companies and individuals interested in the market.

The global Hematopoietic Stem Cell Transplantation (HSCT) market research include the decisive analysis by classifying it on the basis of product type, end-user, and application segments. The development of every segment is assessed along with the forecast of their expansion in the near future. The pertinent facts and figures gathered from the regulatory authorities are presented in the global Hematopoietic Stem Cell Transplantation (HSCT) research report to review the expansion of each segment.

Furthermore, the market is bifurcated on the basis of geographical regions such as North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa. Numerous analytical techniques are used to study the expansion of the global Hematopoietic Stem Cell Transplantation (HSCT) market. It also highlights key parameters of the dominating market players influencing the growth of the industry along with their position in the global market.

Report Highlights:

Hematopoietic Stem Cell Transplantation (HSCT) Market Drivers & Challenges

Global Hematopoietic Stem Cell Transplantation (HSCT) Market Answers the following Key Questions.

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Reasons for Buying Hematopoietic Stem Cell Transplantation (HSCT) market

Thus, the report extends from market scenarios to comparative pricing between major players, cost and profit of the specified market regions. The numerical data is backed up by statistical tools such as SWOT analysis, BCG matrix, SCOT analysis, PESTLE analysis and so on. The statistics are represented in graphical format for a clear understanding of facts and figures.

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Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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Hematopoietic Stem Cell Transplantation (HSCT) Market Trend Forecast And Growth Drivers by 2026 - News Parents