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Stem Cell The Latest Research On Stem Cell Treatments …

December 22, 2016 Knee Pain

There are several clinics throughout the US working with stem cell therapy, and developments in the field are continually growing. Although we primarily use stem cells for treating degenerative conditions and diseases, there are also other studies that utilize similar biologics to further research in the field. Here are just a few of the latest scientific developments this year:

June 2016. Understanding Conversion of Stem Cells into Specific Organ Cells. Stem cells are the basic, universal cell material that allow all cells to develop within our body. We have not been able to readily understand the conversion of the cell into a given organ cell, but that is changing. Researchers have developed a nanoprobe capable of penetrating a stem cell wall and accessing its microRNA to assess how the stem cells divisions become a specific body part cell. They have tracked the stem cell division process for five days. By understanding the mechanics of stem cell RNA in the division process, we are potentially closer to guiding that process for specific organ cells desired for therapies. Read more by visiting the article here.

July 2016. CRISPR and Editing Human Pluripotent Stem Cells. Alternative stem cell sources can be derived from a variety of body tissues. They, just like fetal stem cells, have the capacity to develop into virtually organ cells from any part of the body. The problem has been, what can be done when there is a DNA falw in the cell (making its daughter cells flawed in terms of targeting an organ for repair)? The answer? Editing the stem cell. A specific editor, CRISPR/Cas9 can accomplish this purpose and be an aide to stem cell therapy. Read more by visiting the article here.

August 2016. Treatment for Macular Degeneration. Researchers have discovered a clinically efficient way to take the bodys normal cells (not the bodys normally occurring stem cells) and cause them to form specific cells of retinal pigment epithelium. These cells may ultimately be used to replace cells destroyed by the macular degeneration process. This discovery also has implications for other cell therapies for a variety of degenerative conditions. Read more by visiting the articlehere.

October 2016. Consumer Safety Becoming Clinic Focus. Stem cell treatments have become highly innovative and there is a burgeoning industry as new therapies are developed. A variety of research organizations are developing oversight guidelines for safe and effective stem cell therapy innovations that will provide a greater level of safety in the stem cell clinics providing patient therapies across the United States. Read more by visiting the articlehere.

November 2016. Alternatives for Fetal Stem Cells for Parkinsons Disease. This nervous system disease is characterized by loss of dopaminergic neurons in the brain. Symptoms are treated today with medicines, e.g., dopamine, but experiments with amniotic stem cells injected into the brains of Parkinsons patients have shown some success. The source of these stem cells has had ethical and practical implications limiting widespread application of this therapy. Recent alternative stem cell sources appear poised to make this therapy more viable. Read more by visiting the articlehere.

To date, we have come so far with stem cell research. Todays innovations will generate new therapy strategies, and we cannot wait to see what the future holds.

For Stem Cell Therapy Treatment, or to learn more, please call 844-ME-AGAIN (632-4246).

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Stem Cell The Latest Research On Stem Cell Treatments ...

About Stem Cell Therapy – Progencell – Stem Cell Therapies

Congratulations on taking the first step towards learning more about stem cell therapy.

Adult (Non Embryonic) Stem Cells are undifferentiated cells that have the capability to replace dying cells and regenerate damaged tissue. These special cells target areas of injury, disease and destruction where they are capable of regenerating healthy cells and enabling a persons natural healing processes to be accelerated.

As we gain a deeper understanding of their medical function and apply this knowledge, we are realizing their enormous therapeutic potential to help the body heal itself.

Adult stem cells have been used to repair and regenerate acute and chronically damaged tissues in humans and animals to treat a variety of medical conditions.

Adult stem cells are obtained from sources, including bone marrow, cord blood, peripheral blood and others. Because of their properties, each one has particular advantages and disadvantages.

Once the cells are obtained, their quality can be manipulated and assesed and then be infused in the participant. Contamination and damage of natural cell function may increase with too much manipulation. The possibility of rejection and severe post-treatment complications increases substancially if the stem cell donor is different than the patient to be treated, such as a Graft-Versus-Host-Disease.

Stem cell therapy regenerates cells and specific organs that are affected by disease. According to several studies, Stem Cells have the ability to differentiate into other types of cells (cardiac cells, bone/cartilage, liver cells, nerve, etc.). In addition, these Stem Cells have the ability to chemically detect damaged tissue, home those tissues, and directly repair them. This kind of therapy helps to increase the tissues functionality, resulting in considerable improvement of a persons medical condition.

Many people have improved their health conditions by participating in this research protocol (and have received the benefit of keeping their body systems and organs in optimal condition), even where other treatments have failed to work.

Due to the stem cell research hype all over the world, we recommend individuals gather as much information as possible in order to get to the right people and to the correct treatment. There are clinics in which the stem cells are obtained from an unknown donor source and the risks involved could be very high. It is highly recommendable to use only stem cells directly from the same person in order to perform autologous infusions, by doing so, there is no risk of rejection or complications during the extraction and/or infusion process. Read more about stem cell therapy and its potential.

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About Stem Cell Therapy - Progencell - Stem Cell Therapies

Stem Cell Treatment for Dry AMD Moves Closer to Human …

A new treatment for the most severe form of advanced, dry age-related macular degeneration (AMD) has shown promise in an animal study. Researchers hope the treatment, which involves using a patient's own stem cells to replace lost retina cells, will soon be tested in humans.

There are two forms of AMD: dry and wet. About 80% of people who have AMD have the dry form, and there are several kinds of dry AMD. There is currently no way to treat any kind of dry AMD.

In dry AMD, cells called retinal pigment epithelium (RPE) cells die. These cells nurture light-sensing cells in the retina called photoreceptors. Once the cells die, the photoreceptors also eventually die. This cell death results in the most severe form of dry AMDcalled geographic atrophy. Geographic atrophy can lead to blindness.

The new experimental treatment is designed to replace the dying cells with cells that have been created from a patient's blood cells. In the lab, the researchers convert the patient's cells into induced pluripotent stem cells (iPS) cells. These can become any kind of cell in the body.

In this study, researchers programmed human iPS cells to become RPE cells. The lab-made cells were grown in tiny sheets that were one cell thick. The researchers then inserted the cells into the retinas of rats and pigs. Ten weeks after the cells were implanted, the researchers conducted imaging studies that showed the lab-made cells were integrated within the retina.

The transplanted cells functioned properly, the researchers reported in the journal Science Translational Medicine. These healthy new cells could stop any further vision loss from dry AMD and might even be able to return some lost vision.

"Being able to reprogram stem cells to become missing RPE cells is really exciting technology," said Pravin U. Dugel, MD, an ophthalmologist at Retinal Consultants of Arizona in Phoenix.

"It's still very early and there are a lot of challenges ahead, he said. "Just because it works in rats and pigs doesn't necessarily mean it will work in humans. But we don't have any treatment for dry AMD, so this is something to watch out for."

Dr. Dugel noted that a key concern with any stem cell therapy is that changing the nuclear structure of the cell has the potential to cause cells to multiply uncontrollably and become cancerous. The researchers said they genetically analyzed the RPE cells derived from stem cells and found no genetic mutations linked to tumor growth. "Although it was not seen in this animal study, it always remains a possibility, and that has to be overcome," Dr. Dugel said.

The researchers have started to plan a Phase I clinical trial to test the safety of the treatment in humans. The U.S. Food and Drug Administration must still approve the trial before it can begin.

"If the clinical trial moves forward, it would be the first ever to test a stem cell-based therapy derived from induced pluripotent stem cells for treating a disease," lead researcher Kapil Bharti, PhD, of the National Eye Institute said in a news release.

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Stem Cell Treatment for Dry AMD Moves Closer to Human ...

Treating Serious Injuries With Horse Stem Cell Therapy

Treating injuries in horses, particularly orthopedic injuries, is something which has always been done with difficulty. Every thirdsports horse has a tendon or ligament injury during his career. It takes 9-12 month to heal and 70% of them can not reach the previous results again. A repeated injury also occurs in 66% of cases and scar tissue is formed. Value and the skill level of the horse have also fallen,but not if you choose to treat injuries with horse stem cell therapy.

Of course, horse owners always want to ensure that their animals are receiving the best treatment possible and get back to racing as soon as possible. As a result, many of them are jumping at the opportunity to try stem cells. So lets run through the basics of equine stem cell therapy.

The cells used for the treatment of horse injuries are known as mesenchymal stem cells. These are multipotent stromal cells that can differentiate into a variety of cell types,including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells).There are several ways and methods to get hold of donor stem cells:

These donor stem cells are collected and then grown until there are enough stem cells for treatment. In most cases, this is going to be around 10 million stem cells we see this as the optimal amount to increase the success of the treatment.

Stem cells can be used to treat horse injuries. The greatest success seems to be with injuries to the tendon and ligament.

The proper use of stem cells can help to speed up healing of these areas in horses 3-4 times.

One of the areas where we have seen a lot of success with this treatment is injuries to the Deep Digital Flexor Tendons (DDFT). These tendons help to endure most of the animals weight. This means that if they are damaged, it can cause serious damage to the horse. Damage to these tendons can be tough to treat.

It is believed that using traditional methods of treatment will get the animal fully healed about 29% of the time. Anecdotal evidence seems to suggest that the use of stem cells as a healing method could get the animal back to work 75% of the time.

Medrego experience and cases show even up to 90% of success rate.

Obviously, we do not have a 100% success rate, but having such a high success rate is something which really warrants further research.

There are many ways your horse can injure a muscle even when he is sitting somewhere and you spook him by accident, he can still pull, tear or otherwise injure it.

Its the same as with us, humans. We can injure ourselves in a lot of different ways.

If you are competing with your horse in competitions, then you must know that muscle injury can affect the horses performance. You will see that he is not giving his 100% and is lazy.

That is where horse stem cell therapy comes in.

It treats your horses muscle injury much faster than a standard treatment.

Contact us for more information about how it can treat your horses muscle injury.

Treating your horses injuries will not only make your horse heal faster, but also help your older horse live his days better.

When horses get old, they start to become very lazy and unhappy they dont want to do the things they used to do before.

But with stem cell therapy that can change. Look at that from this point of view would you want to spend all the days in your old age sitting on the couch watching tv all day?

You would not, and the same goes for your old horse he does not want to spend the rest of his life in the barn, but he also does not feel strong enough to do anything else.

Give him that opportunity with stem cell therapy.

Of course, you will have to follow some standard old horse treatment too.

In the future, researchers are considering seeing stem cells assist with helping damaged or diseased organs, dealing with orthopedic disease, or even dealing with laminitis. We are excited to see the impact this will have on stem cell treatment going forward.

Want to order and try the new Stem Cell Treatment for your Horses? Contact us! >>

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Treating Serious Injuries With Horse Stem Cell Therapy

Stem Cell Treatments MI | Michigan Center for Renerative …

How would you like to avoid addictive medications for your chronic pain or progressive disease with a revolutionary, safe and effective alternative? Our own stem cells could provide the answers. Found mainly in our bone marrow and fat, stem cells are powerhouses of healing potential. Imagine being able to use your own stem cells to heal injury! The process itself is relatively simple, which involves isolating the stem cells, concentrating them into a syringe and injecting them where they can do the most good.

Here at The Michigan Center for Regenerative Medicine, we utilize the bone marrow stores over fat for a couple of different reasons. First, they work better for the types of conditions we treat. Second, the FDA restricts techniques aimed at isolating fat cells. Because we pride ourselves on our strict compliance with the FDA, we focus on bone marrow aspiration procedures. Virtually painless, stem cell treatments in Michigan have been used here to successfully treat conditions such as spinal disc herniations, osteoarthritis, tendonitis, bursitis, rotator cuff damage, whiplash, plantar fasciitis and much more.

Tired of pain? Looking to avoid dependence on medication or reduce your chances of surgery? We can help. To find out more, call The Michigan Center for Regenerative Medicine today for your consultation at 248-216-1008.

Stem cell treatments in Michigan carry with them many benefits, not the least of which is to finally incorporate a treatment plan that doesnt simply mask the pain such as through pills and cortisone injections, but that truly addresses the underlying cause.

Stem cell treatments can:

Dr. Thomas S. Nabity, Jr., board-certified in physical medicine, rehabilitation and pain medicine, will conduct the procedure with his team. Harvested cells are isolated in an on-site lab using a centrifuge and flow cytometer to achieve the highest concentration of cells possible.The stem cells are then placed in a syringe and re-introduced into the targeted tissue. This all happens on the same day, performed under either x-ray or ultrasound to ensure precise location for stem cell delivery.The entire procedure takes two hours from start to finish, usually only requiring local anesthetic. However, IV sedation is available if you want it.

Scientifically proven regenerative medicine could be your solution. Every year, more and more patients opt to fix their chronic orthopedic conditions with stem cell treatments over invasive surgery. Are stem cell treatments in Michigan right for you?

We would be happy to provide you with a consultation to answer your questions on stem cell treatments in Michigan. Please call us now at 248-216-1008.

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Stem Cell Treatments MI | Michigan Center for Renerative ...

Stem Cell Alopecia Treatment Market Outlook, Growth by Top Company, Region, Application, Driver, Trends and Forecasts By 2026| Verified Market…

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Stem Cell Alopecia Treatment Market Outlook, Growth by Top Company, Region, Application, Driver, Trends and Forecasts By 2026| Verified Market...

Difference Between Adult and Embryonic Stem Cells | Compare …

The key difference between adult and embryonic stem cells is that adult stem cells are multipotent while embryonic stem cells are pluripotent.

Stem cells are a category of cells with the ability to divide and develop into different types of cells in the body. They are distinguished from the normal cells since they divide and renew themselves over a longer period of time. Moreover, they are unspecialized cells with no specific cellular function in the body. They have the potential to differentiate and become specialized cells in the body such as brain cells, blood cells, and muscle cells. Adult stem cells and embryonic stem cells are two types of stem cells.

1. Overview and Key Difference2. What areAdult Stem Cells3. What are Embryonic Stem Cells4. Similarities Between Adult and Embryonic Stem Cells5. Side by Side Comparison Adult vs Embryonic Stem Cells in Tabular Form6. Summary

Adult stem cells are present in differentiated tissues of the body. These tissues include skeletal muscle, liver, pancreas, brain, eye, dental pulp, skin, bone marrow, blood and lining of the gastrointestinal tract. Moreover, adult stem cells remain in these tissues undifferentiated, with continuous self-renewal and producing identical copies of cells throughout the lifetime of the organism. They undergo differentiation into specialized cells of their tissues of origin when needed.

Figure 01: Adult Stem Cells Repair

Hematopoietic stem cells are a type of adult stem cells present in the bone marrow. They are considered multipotent stem cells as they give rise to different types of blood cells from a single type of cells. Regulated gene expression is responsible for these variations in differentiated cells. It is controlled by special types of transcription factors. Also, stem cells present in the brain are multipotent. They give rise to both muscle and blood cells.

Embryonic stem cells are the undifferentiated cells present in the inner cell mass of the blastocyst a hollow ball of cells developed from the zygote after rapid mitosis. Hence, these stem cells are categorized as stem cells present in the early stages of embryonic development.

Embryonic stem cells are pluripotent. Therefore, they give rise to cells of three germ layers endoderm, ectoderm, and mesoderm except the placenta and umbilical cord. Pluripotency distinguishes embryonic stem cells from adult stem cells.

Figure 02: Embryonic Stem Cells

Embryonic stem cells provide valuable assistance as a renewable resource in the study of diseases and for testing of potential therapeutics and drugs. Under defined conditions, embryonic stem cells possess the ability to divide indefinitely.

Adult stem cells and embryonic stem cells are the two main types of stem cells. The key difference between adult and embryonic stem cells is that adult cells are multipotent as they have a limited ability to differentiate while embryonic stem cells are pluripotent as they have the ability to differentiate into any cell type. Also, a further difference between adult and embryonic stem cells is that the embryonic stem cells can readily grow in cell cultures while the growth of adult stem cells in cell cultures is very challenging.

Moreover, a significant difference between adult and embryonic stem cells is that the adult stem cells are present in adult tissues while embryonic stem cells are present in the early development at the blastocyst stage.

The key difference between adult and embryonic stem cells lies in their potency. That is; the adult stem cells are multipotent while embryonic stem cells are pluripotent. Adult stem cells are present in differentiated tissues of the body such as liver, pancreas, skeletal muscle, etc. Regulated gene expression is responsible for variations in differentiated cells derived from adult stem cells. On the other hand, embryonic stem cells are present in the inner cell mass of the blastocyst. These stem cells give rise to the cells of ectoderm, endoderm, and mesoderm. Furthermore, embryonic stem cells divide indefinitely under defined conditions. This is the summary of the difference between adult and embryonic stem cells.

1. The Adult Stem Cell. National Institutes of Health, U.S. Department of Health and Human Services, Available here.2. Stem Cells. A Closer Look at Stem Cells, Available here.

1. Stemcellheartrepair By US gov -(Public Domain) via Commons Wikimedia2. Human embryonic stem cells only A : Human_embryonic_stem_cells.png: (Images: Nissim Benvenisty)derivative work: Vojtech.dostal (talk) Human_embryonic_stem_cells.png (CC BY 2.5) via Commons Wikimedia

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Difference Between Adult and Embryonic Stem Cells | Compare ...

Science Fiction Becoming Reality – Reporter Magazine

by Tyler English | published Dec. 11th, 2019

illustration by Darius Serebrova

Ever wonder where those neon yellow, green, blue and pink fish came from? You know, the ones that have all the matching accessories: tanks, decorations, rocks and their own special ultraviolet light? Well, as it turns out, a team ofscientists in Singapore were the first ones to genetically modify fish to glow in such a way.

Genetic editing in small animals and plants has been aroundsince the 1970s, according to Synthego, a company that providesgeneticallyedited stem cells. Starting with plants and bacteria, scientists began to explore the realm of DNA and genetics. As their understanding of the proteins grew, so did their curiosity.

When scientists learned how to modify the genes of small, simple organisms, they began to wonder, "How could this be applied to humans?"

The scientific community is stirring with the emergence of CRISPR DNA,more specifically known as the CRISPR-Cas9 protein.CRISPR stands forClustered Regularly Interspaced Short Palindromic Repeats.CRISPR is a faster, cheaper and more accurate way of editing the genome, according to theNational Institute of Health.By sending in two different pieces of CRISPR DNA,scientists are able to modify genes. To do so, theycutout areas of genes that aren'tperforming how they should be or as they're expected to.

Dr. Sandi Connelly, a principallecturer in the Thomas H. Gosnell School of Life Sciences, explained how DNA works and what the CRISPRCas-9 protein actually does. Connelly compared DNA to a street of houses each person has different foundations that sprout out different and unique homes.

CRISPR is a piece of DNA, and we [scientists] attach to it an enzyme ...it cuts the DNA at a very specific place like a pair of scissors, Connelly said. When we look at CRISPR, typically we look at CRISPR Cas-9."

Whereas CRISPR is the DNA itself, Cas-9 is the enzyme, a specialized protein that splits the DNA.Connelly said that this allows for both the CRISPR DNA and the original DNA to stick together like magnets. However, due to the specificity of this technique, scientists need to know where in the DNA they'relooking.

Using those same enzymes, we can cut [and] place back inthe good gene, Connelly said.

Now, this technique would not be doneby injecting the CRISPR DNA directlyinto a fully grown adult. Instead,scientists would take a sample of a persons bone marrow and alter the genes of those cells. Since bone marrow is responsible for producing red blood cells, the new altered bone marrow will produce cells with the new DNA.

Connelly saidthechangeswouldnot be instantaneous.The human body replaces a majority of its cells within 13 days, soit would take around two weeks for the newly edited gene to be present in the human body.

The ability to now alter genes of morecomplexorganisms brings with it a variety of applications. Plants can be changed to increase nutritional value and pesticidal properties,whereas bacteria can be used to generate hormones and medicines.

Dr. David Holtzman,an adjunct professor in the College of Science, understands how gene editing is used and what it could be used for.

Most people are familiar with it [gene editing] for things like modifying plants ...[but] there is a lot of misunderstanding about gene editing, Holtzman said.

There is a lot of misunderstanding about gene editing.

CRISPR has begun to work its way into at-home kits, where those with some scientificexpertise can genetically modify their own plants to glow or be a different color. This is fairly simple in the world of gene editing as it is changing a simple expressed trait one that isbiologically shown.

Genes decide what traits a person has, but that persons environment and what happens to their body determines how those traits are expressed. As gene editing becomes more and more innovative, Holtzman said that there are limitations to what gene editing can and cannot do.

It turns out most traits are more than one gene, Holtzman said.

Holtzman used hair color as an example. Numerous genes and sections of DNA code for what an individual's hair colorwill be. Itcan behard and time-consuming to find the right area of the DNA to target for modification.

Connelly talked about the idea of changing hair coloras well,but took it a few steps further. Shesuggestedthat we may start wanting to create offspring that all have blonde hair and blue eyes, which realistically we could accomplish. This then opens parents up to the ideas of having all male children or all female children.

In recent years, science has progressed faster than we could have thought.What appeared to be science fiction in the past is inching ever closer to our scientific reality.

The ability to do [new]things happens a lot faster than our understanding of what we are doing, Holtzman said.

Regardless of the potential scientific progress that could be made, Holtzman, Connelly and other members of the scientific community are having conversations about what should be done with this technology. Where should the limits lie, and how far should humans gowith genetic technology?

"Where should the limits lie, and how far should humansgowith genetic technology?"

If our parents changed our genes, they would also be changing the genes of all of our descendants by extension. Did they consent to something like that?

Some might argue, whether we gene edit or not, we dont really have control over what our parents did, Holtzman said. There is the possibility that if we changed [certain genes]then we can change them back.

Reversal isn't a guarantee, though.

Holtzman mentioned ways in which gene editing could greatly improve the quality of life for all humankind, such as curing Alzheimers disease. Connelly brought up how easy it would be to reduce the effects of aging using genetic modification.

The consequences of the choices made nowmay not affect the generation making them. As the movement to improve the genetic composition of the human race pushes forward,plots in sci-finovelsmay no longer be abstract, distant futures. Rather, for better or worse, they could bethe reality we are setting up for generations to come.

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Science Fiction Becoming Reality - Reporter Magazine

Thinning Hair? Here are 8 Ways to Make It Fuller and Shinier – Self

It may be a little distressing to notice, possibly for the first time, that you have thinning hair. For many of us, its a natural part of aging that doesnt necessarily need to be treated. But aging is only one of many factors that can cause or exacerbate thinning hairand some of these causes should be addressed.

Once you know whats causing the issue, it becomes a lot easier to figure out how to manage it. Below, SELF talked to several experts about ways to make your hair feel thicker and look shinier, as well as ways to prevent more hair thinning.

The first thing to know about hair loss is that its actually a bit complex. Your hair grows in three stages, SELF explained previously. These include a growth phase from a root in the hair follicle, a transitional phase when the growing stops, and a resting phase, after which the hair falls out and the follicle takes a break before growing another hair.

Its totally normal to lose between 50 and 100 hairs a day, according to the American Academy of Dermatology (AAD), which you might notice on your pillow in the morning, on your hairbrush, or in the shower. If you go a few days without showering, you might notice more than a single days worth of hair in the shower, which may be a little disconcerting, but is still totally normal.

Youre born with about 100,000 follicles on your scalp, and youll never gain or lose any, the AAD says. However, as you age, some follicles may stop growing hair and you may experience hair loss (also called anagen effluvium). When and how this happens is influenced by a bunch of factors, including our genetics and the natural hormonal changes we experience as we age, Shilpi Khetarpal, M.D., dermatologist at Cleveland Clinic, tells SELF.

But you might also experience hair shedding at certain points in your life, a process thats separate from hair loss. Hair shedding (also called telogen effluvium) is more often caused by temporary changes in hormones, like giving birth, stopping hormonal birth control, or experiencing life stressors, like undergoing chemotherapy or recovering from a serious illness. Nutritional deficiencies, harsh hair products, and certain hair styles can also cause hair shedding, the AAD says.

If your hair is shedding, that means its falling out more quickly than it should be because its being shoved into the resting phase too early, SELF explained previously. But if youre experiencing hair loss, that means theres something stopping the hair from growing in the first place. And, because hair loss can be caused by different factors, its important to figure out which one youre dealing with before trying to treat it.

If you dont know if your thinning hair is due to hair shedding or hair loss, you should check in with an expert. Its also important to talk to a dermatologist if youre losing more than 100150 hairs per day or you notice other issues (bald spots, hair shafts that break easily, or an itchy or burning scalp), Alina G. Bridges, D.O., dermatologist and dermatopathologist at the Mayo Clinic, tells SELF. These could signal a more serious hair-loss issue or an underlying condition (like scalp psoriasis) that warrants professional treatment.

If youre not sure how many hairs youre losing in a single day (understandable) you can test it with the 60-second hair count: Comb your hair forward from the back of your head to the front for a full minute. Collect and count the hairs that were shed through this processyou should see between 10 and 20 strands, depending on your age. If you see more than that, you might be dealing with some excess hair loss. To get the most accurate idea of how many hairs youre losing, you might want to do this a few days in a row.

Once you know what youre up against, there are some easy ways to help manage thinning hair at home or with the help of an expert. Here are the top tips we learned from dermatologists and hair stylists on how to protect your hair and restore some of its fullness and shine.

You likely dont need to wash your hair every day. In fact, Samantha DelaFuente, a stylist at Marie Robinson Salons in New York and Miami, tells SELF that she recommends washing only two or three times a week. Dont be afraid of dirty hair, she says.

And dermatologists agree: Washing too often strips your hair of necessary oils, and washing infrequently can leave hair dull and limp, especially if you overuse dry shampoo, Dr. Bridges says. If you have natural hair, which tends to be drier and more prone to breakage, clean it even less frequently, Dr. Khetarpal says.

Moisturizing shampoos formulated without sulfateschemicals in shampoos that help clean but can also be drying on sensitive or dry scalpsare a safe bet for everyone. In particular, celebrity stylist Tym Wallace tells SELF he recommends Oribe Gold Lust Repair & Restore Shampoo ($154, Bloomingdales or Moroccanoil Moisture Repair Shampoo ($24, Nordstrom).

Conditioner gives your hair shine and reduces static electricity, the AAD explains, which is why it improves the look and feel of dull or damaged hair. Apply to the ends of the hair and work your way up, DelaFuente says. A little goes a long way; the more conditioner you use, the flatter your hair will be.

Remove tangles with a wide-tooth comb and rinse with cool water, which closes the cuticle and makes the hair shiny, Dr. Bridges explains.

If youre looking for conditioners that can specifically help dull or thinning hair, Eric Leonardos, stylist at Ted Gibson, tells SELF he recommends Klorane Gel Conditioner with Peony ($20, Ulta), which contains soothing and hydrating ingredients, or Shu Uemura Muroto Volume Conditioner ($58, Shu Uemura), which has a lightweight formula that wont weigh down hair.

After shampooing and conditioning, try using a leave-in product, like a conditioner or detangler, which will boost moisture and provide heat protection before styling.

Wallace recommends the moisturizing and protecting Its a Ten Miracle Leave-In Conditioner Spray Product ($38, Ulta) as well as the truly multitasking Form Multitask 3-in-1 Leave-in Lotion ($32, Form Beauty).

Once a week, apply a deep conditioning mask for extra moisturizing powers, and leave on for 1520 minutes, Dr. Bridges says. Finish by rinsing with cool water.

Leonardos recommends LOreal Elvive Total Repair 5 Damage-Erasing Balm, which he says lends shine and smooths the hair cuticle ($8, Amazon), and Shu Uemura Ultimate Reset Hair Mask, which he explains imparts a smooth texture and smells divine ($68, Sephora).

DelaFuente swears by Milbon Plarmia Hairserum Treatment ($35, Amazon), which comes in formulas for fine-to-medium and coarse hair, and Christophe Robin Regenerating Mask With Prickly Pear Seed Oil ($71, Sephora), a product thats made without parabens and sulfates, which may be irritating to some sensitive scalps.

On his clients, Wallace uses Moroccanoil Restorative Hair Mask ($43, Amazon), made with moisturizing argan oil and shea butter, or Its a Ten Miracle Hair Mask ($32, Ulta), which is designed to nourish color-treated, heat-styled hair.

Rub a small amount of serum through your wet hair before styling or air-drying. In addition to adding shine and combating fly-aways, these products help to prevent frizz.

Wallace recommends Paul Mitchell Smoothing Super Skinny Serum ($21, Ulta), which also helps speed up the drying process, while DelaFuente swears by Alterna Haircares CAVIAR Anti-Aging Restructuring Bond Repair 3-in-1 Sealing Serum ($38, SkinStore), especially for damaged or drier hair.

As an alternative, oilssuch as argan, coconut, and jojobaprovide similar benefits as serums, but actually penetrate deeper into the hair, Dr. Bridges says. They can be applied to wet hair or to dry hair as an anytime treatment or shine enhancer. Leonardos recommends the custom hair oils from Prose ($48).

If styling with a hot tool, do your best to limit heat to a maximum of about 400 degrees Fahrenheit for normal hair, 390 degrees for color-treated, and 350370 degrees for fine, processed hair to avoid causing damage, Dr. Bridges says. Not all heat tools have temperature readingsor the ability to change the temperature, so it may be worth investing in a tool that does have those options if you heat style frequently, such as the CHI Temperature Control Hairstyling Iron ($100, Ulta) or Harry Josh Pro Tools 2-in-1 Ceramic Marcel Curling Iron ($185, Dermstore).

To get a little more lift, try applying volumizing root spray to your roots, then lightly adding mousse to the mid-lengths and ends, Leonardos suggests. In particular he recommends wallet-friendly VERB Volume Spray ($18, Amazon) or, for a longer-lasting option, Oribe Maximista Thickening Spray ($39, Dermstore).

For mousse, DelaFuente swears by Alternas Bamboo Volume Weightless Whipped Mousse ($22, Ulta), which provides long-lasting hold without making hair feel crunchy. And Wallace likes Big Sexy Hair Root Pump Spray Mousse ($19, Ulta). This product actually comes out of the can as a spray and then transforms into a mousse, which might make it a little easier to work with.

Then blow-dry at the roots, using hot or Velcro rollers, to add more volume and set the style. Finish with cool air and a texture spray, such as SGX NYC the Do-It-All 3-in-1 Dry Texture Spray ($9, Amazon), which Leonardos says lends a natural, matte texture; for a longer-lasting option without product build-up, try Oribe Dry Texturing Spray ($46, Dermstore). DelaFuente prefers Milbons Thickening Mist 4 ($26, Amazon), which she says doesnt leave hair feeling stiff or sticky.

One particular type of hair losstraction alopeciais caused by chronic stress on the hair follicle, often due to too-tight hair styles, and its especially common among black women. But if you can treat traction alopecia early on, you can adjust your habits and keep the condition from worsening; in fact, you can prevent hair loss from becoming permanent.

In particular, make sure youre not wearing hairstyles that pull on the scalplike high, tight ponytails, braids, or dreadsfor extended periods of time.

If changing up your styling habits hasnt helped, then it may be worth trying one of two daily-use OTC treatment options. The first one, minoxidil, is available in liquid or foam form at 2% and 5% concentrations, Dr. Bridges says.

This medication prolongs the growth phase of hair, she says, which prevents any more hair loss and may also stimulate new hair growth. However, be prepared to wait: Youll have to use minoxidil daily for at least four months before seeing any effects. And when you stop using it, any new hair is likely to just fall out. Also, its important not to use this if youre pregnant or nursing.

As an alternative, you can try hair-growth products containing a combination of redensyl, capixyl, and procapil (RCP), ingredients that are thought to target hair follicle stem cells, Dr. Bridges says. A study published earlier this year looked at the effects of RCP and minoxidil in 120 men with hair loss over 24 weeks. The results showed that those who received RCP treatment had significantly more improvement in their hair during the study compared to the minoxidil group. However, its not clear how well these results would translate to women or if the over-the-counter products out there containing these ingredients would stack up to those used in the study.

In some cases, youll need a dermatologists help to diagnose and manage your thinning hair. As we mentioned previously, thats especially true if you think you may be dealing with an underlying health condition or if you have specific symptoms, like bald spots or itchiness.

Depending on the root cause of your hair issues, your derm may recommend prescription medications, including birth control pills and spironolactone, Dr. Khetarpal says. These options can target hormone-related hair loss.

For a pricier, in-office approach, you could try platelet-rich plasma (PRP) scalp injections, which generally require repeated treatments that may cost around $1,000 per session. With this method, doctors draw blood, separate out the platelets, and then inject these platelets into the scalp. Platelets may help stimulate hair growth thanks to the growth factors they contain, Dr. Khetarpal says. But so far scientific evidence supporting PRP for this use has been mixed. For instance a double-blind study published in Dermatologic Surgery in 2016 found that more patients who received PRP for hair loss reported a substantial improvement in their hair loss and hair thickness compared to those in the placebo group. However, laboratory testing didnt find any significant difference between the results of those receiving PRP and those who got the placebo treatment.

Healthy hair requires adequate nutrients, especially things like vitamin D and biotin (vitamin B7). So if you think your hair loss could be due to an underlying nutritional deficiency, check with your doctor for a blood test. They may recommend supplementing with specific forms of the vitamins, Dr. Khetarpal says.

There are other serious conditions that can contribute to hair loss, including autoimmune disorders and nutritional deficiencies. If youre not sure whats causing your hair loss or you havent had any success with these other tips, its important to check in with a dermatologist to figure out whats going on.

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Thinning Hair? Here are 8 Ways to Make It Fuller and Shinier - Self

Former Kansas congressman assists with release of U.S. prisoner in Iran – The Garden City Telegram

Former U.S. Rep. Jim Slattery parlayed decades of international relationship-building to assist with gaining freedom of a Chinese-American captive and the release of an Iranian accused of violating trade sanctions.

Slattery, who served an eastern Kansas district in the U.S. House for more than a decade, worked as an attorney and consultant after leaving Congress. He forged relationships along the way that included Majid Ravanchi, a former University of Kansas student now serving as Irans ambassador to the United Nations. In an interview Monday, Slattery said he also was familiar with Iran Foreign Minister Mohammad Javad Zarif.

He contributed to dialogue that led to exchange of Xiyue Wang, a Princeton University doctoral student arrested in Tehran during a research trip, accused of being a spy and incarcerated the past three years, for Massoud Soleimani, an Iranian researcher held since 2018 in the United States on charges of breaking U.S. trade sanctions.

"Bottom line is two families are reunited," Slattery said. "One in Iran and one in Princeton, New Jersey."

On Saturday, the administration of President Donald Trump confirmed the brokered agreement would result in release of Soleimani and Wang. The president said in a statement freeing Americans was of vital importance to his administration and "we will continue to work hard to bring home all our citizens wrongfully held captive overseas."

Slattery, a Democrat engaged for 15 years in outreach projects in Iran, said he was invited to participate by Wang's family attorney. Slattery said he worked pro bono on the project, and told Zarif, the Iranian foreign minister, during a September meeting in New York there was no credible evidence Wang was engaged in espionage.

"I was completely convinced he was not a spy and completely convinced he was being held on bogus charges," Slattery said.

Wang was taken into custody in 2016, convicted on two counts of espionage and sentenced to 10 years in prison in Tehran.

The former Kansas congressman also concluded the U.S. Department of Justice had a weak case against Soleimani, a stem-cell researcher arrested after invited by the Mayo Clinic to come to Minnesota.

The case against him involved exportation of a growth factor used in research to Iran, but Slattery said Soleimani's lawyers could have convincingly argued in court the material was covered by a medical exception to the trade ban.

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Former Kansas congressman assists with release of U.S. prisoner in Iran - The Garden City Telegram