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Brooks Koepka slips on wet concrete, withdraws from CJ Cup – Golfweek

World No. 1 Brooks Koepka has withdrawn from the CJ Cup.

Koepka released a statement in which he says that he slipped and aggravated an injury on his left knee.

The full statement, released on the PGA Tours twitter account, reads:

During the course of Fridays round, I slipped on wet concrete aggravating a previous injury to my left knee. After consulting with my doctor, I have been advised to withdraw from the CJ Cup and head home for further tests. I appreciate everyones concerns and support. Ill keep you posted as I learn more.

CJ CUP:Scores|Photos |Updates

A little more than two weeks ago, ahead of his season debut in the Shriners Hospitals for Children Open at TPC Summerlin in Las Vegas, Koepka revealed that he had undergone a stem cell procedure for a partially torn patella tendon. He did it to relieve discomfort and strengthen a left knee that had been bugging him since March.

The procedure was performed Sept. 2 in Orlando.

Its stem cell, so they go in and inject it into my knee, Koepka said. Im watching it on the screen, as they were doing it, and it was probably one of the most painful things, I was screaming when they did it.

The 29-year-old limped out of the clinic and stayed off his feet best he could for three days, then started rehabbing the area.

Koepka shot 69-75 over the first two rounds this week in Korea, which had him at even par, T-51 in the no-cut, 78-man field.

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Brooks Koepka slips on wet concrete, withdraws from CJ Cup - Golfweek

Stem Cell Banking Market was valued at $1986 million in 2016 – Markets Gazette

A fresh report titled Stem Cell Banking Market has been presented by KD market insights. It evaluates the key market trends, advantages, and factors that are pushing the overall growth of the market. The report also analyzes the different segments along with major geographies that have more demand for Stem Cell Banking Market. The competition analysis is also a major part of the report.

The global stem cell banking market was valued at $1,986 million in 2016, and is estimated to reach $6,956 million by 2023, registering a CAGR of 19.5% from 2017 to 2023. Stem cell banking is a process where the stem cell care isolated from different sources such as umbilical cord and bone marrow that is stored and preserved for future use. These cells can be cryo-frozen and stored for decades. Private and public banks are different types of banks available to store stem cells.

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Increase in R&D activities in regards with applications of stem cells and increase in prevalence of fatal chronic diseases majorly drive the growth of the global stem cell banking market. Moreover, the large number of births occurring globally and growth in GDP & disposable income help increase the number of stem cell units stored, which would help fuel the market growth. However, legal and ethical issues related to stem cell collections and high processing & storage cost are projected to hamper the market growth. The initiative taken by organizations and companies to spread awareness in regards with the benefits of stem cells and untapped market in the developing regions help to open new avenues for the growth of stem cell banking market in the near future.

The global stem cell banking market is segmented based on cell type, bank type, service type, utilization, and region. Based on cell type, the market is classified into umbilical cord stem cells, adult stem cells, and embryonic stem cells. Depending on bank type, it is bifurcated into public and private. By service type, it is categorized into collection & transportation, processing, analysis, and storage. By utilization, it is classified into used and unused. Based on region, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

KEY MARKET BENEFITS

This report offers a detailed quantitative analysis of the current market trends from 2016 to 2023 to identify the prevailing opportunities.

The market estimations provided in this report are based on comprehensive analysis of the key developments in the industry.

In-depth analysis based on geography facilitates in analyzing the regional market to assist in strategic business planning.

The development strategies adopted by key manufacturers are enlisted in the report to understand the competitive scenario of the market.

KEY MARKET SEGMENTS

By Cell Type

Umbilical Cord Stem Cell

Cord Blood

Cord Tissue

Placenta

Adult Stem Cell

Embryonic Stem Cell

By Bank Type

Public

Private

By Service Type

Collection & Transportation

Processing

Analysis

Storage

By Utilization

Used

Unused

By Region

North America

U.S.

Canada

Mexico

Europe

Germany

UK

France

Spain

Italy

Rest of Europe

Asia-Pacific

Japan

China

Singapore

India

South Korea

Rest of Asia-Pacific

LAMEA

Brazil

Saudi Arabia

South Africa

Rest of LAMEA

KEY PLAYERS PROFILED

Cord Blood Registry

ViaCord

Cryo-Cell

China Cord Blood Corporation

Cryo-Save

New York Cord Blood Program

CordVida

Americord

CryoHoldco

Vita34

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Table of Content

CHAPTER 1: INTRODUCTION

1.1. Report description1.2. Key benefits for stakeholders1.3. Key market segments1.4. Research methodology

1.4.1. Secondary research1.4.2. Primary research1.4.3. Analyst tools and models

CHAPTER 2: EXECUTIVE SUMMARY

2.1. CXO perspective

CHAPTER 3: MARKET OVERVIEW

3.1. Market definition and scope3.2. Key findings

3.2.1. Top investment pockets3.2.2. Top winning strategies

3.3. Porters five forces analysis3.4. Top Player Positioning3.5. Market dynamics

3.5.1. Drivers

3.5.1.1. Large number of newborns3.5.1.2. Increase in R&D activities for application of stem cells3.5.1.3. Increase in prevalence of fatal chronic diseases3.5.1.4. Growth in GDP and disposable income

3.5.2. Restraints

3.5.2.1. Legal and ethical issues during collection of stem cells3.5.2.2. High processing and storage cost3.5.2.3. Lack of acceptance and awareness

3.5.3. Opportunities

3.5.3.1. Initiatives to spread awareness3.5.3.2. Untapped market in developing regions

CHAPTER 4: STEM CELL BANKING MARKET, BY CELL TYPE

4.1. Overview

4.1.1. Market size and forecast

4.2. Umbilical Cord Stem Cells

4.2.1. Key market trends and growth opportunities4.2.2. Market size and forecast4.2.3. Market analysis, by country4.2.4. Cord Blood

4.2.4.1. Market size and forecast

4.2.5. Cord Tissue

4.2.5.1. Market size and forecast

4.2.6. Placenta

4.2.6.1. Market size and forecast

4.3. Adult stem cells

4.3.1. Key market trends and growth opportunities4.3.2. Market size and forecast4.3.3. Market analysis, by country

4.4. Embryonic stem cells

4.4.1. Key market trends and opportunities4.4.2. Market size and forecast4.4.3. Market analysis, by country

Continue

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About KD Market Insights

KD Market Insights offers a comprehensive database of syndicated research studies, customized reports, and consulting services. These reports are created to help in making smart, instant and crucial decisions based on extensive and in-depth quantitative information, supported by extensive analysis and industry insights.

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Stem Cell Banking Market was valued at $1986 million in 2016 - Markets Gazette

Infanticide in US Abortion Mills – Church Militant

CLICK ABOVE TO WATCH VIDEO

TRANSCRIPT

Abortion mills are committing infanticide.

This is the bombshell news being revealed in the trial of undercover journalists David Daleiden and Sandra Merritt, who exposed Planned Parenthood's trafficking in aborted babies' body parts.

These newborns are not only born alive their organs are harvested for research, even as their hearts are still beating.

In a court brief earlier this month, Daleiden's attorneys documented the experience of Dean Alberty, who once worked with a Planned Parenthood abortion mill in Kansas City.

Alberty testified that he "had been handed whole fetuses from Planned Parenthood doctors and had harvested beating hearts."

He also described "a live birth of twins who were actually cuddling each other."

After Alberty refused to harvest their organs, "the abortion doctor drowned them in a pan of water."

Stem cell researcher Dr. Theresa Deisher told Daleiden "the most horrifying aspect of the use of the remains of aborted fetuses was that some of the babies had to be alive, have beating hearts when they were harvested."

Researchers justify the illegal practice by claiming only live hearts have research value.

Daleiden uncovered the practice of StemExpress, a company specializing in providing U.S. researchers with "whole hearts ... as well as brains, livers and other organs."

A deeper look revealed the scale of the operation, with StemExpress providing babies' organs and tissue to 48 universities and eight private firms across the country.

California Attorney General Xavier Becerra a self-identified Catholic is prosecuting Daleiden and Merritt for exposing Planned Parenthood's trafficking in aborted babies' body parts.

He contends that harvesting organs from newly born infants is protected by the state's abortion statutes, declaring that California law is clear that abortion is not murder.

But in this case, it's clear this is no longer about abortion, but infanticide.

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Infanticide in US Abortion Mills - Church Militant

3 siblings with rare, life-threatening blood disorder in need of bone marrow transplants CNN – WBAL Baltimore

Three young siblings in Ohio are among thousands of people across the country who are in need of bone marrow transplants.Three-year-old Ava Langenhop, her 2-year-old sister, Olivia, and their 2-week-old brother, Landon, have all been diagnosed with a life-threatening blood disorder called leukocyte adhesion deficiency type 1.As a baby, Ava often had illnesses, including ear infections and colds, but this year her parents became more concerned."She started getting infections every time she would get a scrape," said her mom, Alicia Langenhop.Doctors at Cincinnati Children's Hospital diagnosed her with the rare disease and the family was told a stem cell donor would be needed as part of her treatment.Her sister Olivia was tested as a possible donor, but it was determined she has the same disorder."We were kind of in shock, kind of feeling like we're living someone else's life, like there's one kid, now two of them," Langenhop said."They're such sweet girls, just perfect in every way except for this one unfortunate flaw with their bodies," said the girl's father, Jon Langenhop.The Langenhops dealt with this devastating news while Alicia was pregnant with Landon. Since both parents were carriers, they were told there was a 25% chance Landon would also have LAD1, and two days after he was born, tests confirmed he did.Erica Sevilla, from Be the Match, stressed it's simple to be tested for the donor registry by going online to request a kit, swabbing your cheeks and sending it back in. In most cases, those found to be matches would not have to undergo surgery."Eighty percent of the time, it resembles a blood donation or a plasma donation where blood is extracted through your arm in a nonsurgical procedure," Sevilla said.According to Be the Match, there are 14,000 people in the U.S. waiting for a bone marrow transplant. In a given year, 10,000 of them won't find one even though there are 30 million people on the registry around the world."What surprises many people is that only 30% of patients will find a match within their household or within their family," Sevilla said.The Langenhop family have accumulated about $25,000 in medical bills since the diagnoses. A GoFundMe page has been set up to help them with bills and living expenses.The family is hoping for "10 out of 10 matches" to give their children their best chances at a healthy life. Perfect matches for the girls have not been found. Possible perfect matches for Landon may have been located, but more testing is needed.In the meantime, the Langenhops pray that each one of their kids will receive a transplant one by one. They also hope their personal story sheds light on the importance of the donor registry."Even if it's not helping our children, there are tons of people out there that need a bone marrow transplant," Jon said.

Three young siblings in Ohio are among thousands of people across the country who are in need of bone marrow transplants.

Three-year-old Ava Langenhop, her 2-year-old sister, Olivia, and their 2-week-old brother, Landon, have all been diagnosed with a life-threatening blood disorder called leukocyte adhesion deficiency type 1.

As a baby, Ava often had illnesses, including ear infections and colds, but this year her parents became more concerned.

"She started getting infections every time she would get a scrape," said her mom, Alicia Langenhop.

Doctors at Cincinnati Children's Hospital diagnosed her with the rare disease and the family was told a stem cell donor would be needed as part of her treatment.

Her sister Olivia was tested as a possible donor, but it was determined she has the same disorder.

"We were kind of in shock, kind of feeling like we're living someone else's life, like there's one kid, now two of them," Langenhop said.

"They're such sweet girls, just perfect in every way except for this one unfortunate flaw with their bodies," said the girl's father, Jon Langenhop.

The Langenhops dealt with this devastating news while Alicia was pregnant with Landon. Since both parents were carriers, they were told there was a 25% chance Landon would also have LAD1, and two days after he was born, tests confirmed he did.

Erica Sevilla, from Be the Match, stressed it's simple to be tested for the donor registry by going online to request a kit, swabbing your cheeks and sending it back in. In most cases, those found to be matches would not have to undergo surgery.

"Eighty percent of the time, it resembles a blood donation or a plasma donation where blood is extracted through your arm in a nonsurgical procedure," Sevilla said.

According to Be the Match, there are 14,000 people in the U.S. waiting for a bone marrow transplant. In a given year, 10,000 of them won't find one even though there are 30 million people on the registry around the world.

"What surprises many people is that only 30% of patients will find a match within their household or within their family," Sevilla said.

The Langenhop family have accumulated about $25,000 in medical bills since the diagnoses. A GoFundMe page has been set up to help them with bills and living expenses.

The family is hoping for "10 out of 10 matches" to give their children their best chances at a healthy life. Perfect matches for the girls have not been found. Possible perfect matches for Landon may have been located, but more testing is needed.

In the meantime, the Langenhops pray that each one of their kids will receive a transplant one by one. They also hope their personal story sheds light on the importance of the donor registry.

"Even if it's not helping our children, there are tons of people out there that need a bone marrow transplant," Jon said.

Original post:
3 siblings with rare, life-threatening blood disorder in need of bone marrow transplants CNN - WBAL Baltimore

Sunny days and chilly nights this weekend – WMTW Portland

Sunny days and chilly nights this weekend

Updated: 8:32 AM EDT Oct 19, 2019

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GOOD MORNING, I'M METEOROLOGIST SARAH LONG...THIS MORNING' HEADLINES IN JUST A MOMENT, BUT FIRST...A QUIET AND BRIGHT WEEKEND... SATURDAY SUNSHINE... LIGHTER WIND... TEMPERATURES TODAY WILL BE IN THE MID 50S FOR MOST...TONIGHT CLEAR AND CHILLY...LOWS EARLY SUNDAY IN THE 20S INLAND AND 30S SOUTH AND COAST...DURING THE DAY WE WILL START WITH PLENTY OF SUN...SOME LATE DAY CLOUDS ARRIVING...HIGHS AGAIN IN THE 50S...SOME HIGH CLOUDS SUNDAY NIGHT WILL HELP TEMPERATURES STAY SLIGHTLY WARMER FOR MONDAY MORNING...WE START MONDAY IN THE 30S AND 40S...PARTLY SUNNY AND A LITTLE MILDER NEAR 60 DEGREES... TUESDAY THE CLOUDS WILL INCREASE AND TEMPERATURES WILL STAY IN THE 50S...RAIN ARRIVES OVERNIGHT AND STICKS AROUND INTO WEDNESDAY WITH BREEZY AND WET CONDITIONS...1 TO 2 INCHES OF RAIN LIKELY LATE TUESDAY AND THROUGH WEDNESDAY... CLEARING OUT LATER WEDNESDAY AND THE END OF THE WEEK FEATURES A MIX OF SUN AND CLOUDS ALONG WITH SEASONABLE TEMPERATURES IN THE MID TO UPPER 50S...WATCHING FOR A POSSIBLE SOGGY START TO NEXT WEEKEND WITH RAIN EXPECTED SATURDAY...WE'LL KEEP YOU UPDATED MORE THAN 30- GOOD MORNING, I'M METEOROLOGIST SARAH LONG...THIS MORNING' HEADLINES IN JUST A MOMENT, BUT FIRST...A QUIET AND BRIGHT WEEKEND... SATURDAY SUNSHINE... LIGHTER WIND.. TEMPERATURES TODAY WILL BE IN THE MID 50S FOR MOST...TONIGHT CLEAR AND CHILLY...LOWS EARL SUNDAY IN THE 20S INLAND AND 30S SOUTH AND COAST...DURING THE DAY WE WILL START WITH PLENTY OF SUN...SOME LATE DAY CLOUDS ARRIVING...HIGHS AGAIN IN THE 50S...SOME HIGH CLOUDS SUNDAY NIGHT WILL HELP TEMPERATURES STAY SLIGHTLY WARMER FOR MONDAY MORNING...WE START MONDAY IN THE 30S AND 40S...PARTLY SUNNY AND A LITTLE MILDER NEAR 60 DEGREES... TUESDAY THE CLOUDS WILL INCREASE AND TEMPERATURES WILL STAY IN THE 50S...RAIN ARRIVES OVERNIGHT AND STICKS AROUND INTO WEDNESDAY WITH BREEZY AND WET CONDITIONS...1 TO 2 INCH

Sunny days and chilly nights this weekend

Updated: 8:32 AM EDT Oct 19, 2019

How's the weather looking for your weekend? Get your latest Maine's Total Weather video forecast from Meteorologist Sarah Long.

How's the weather looking for your weekend? Get your latest Maine's Total Weather video forecast from Meteorologist Sarah Long.

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Sunny days and chilly nights this weekend - WMTW Portland

Storms expected to finish the weekend – KCCI Des Moines

Storms expected to finish the weekend

Updated: 6:57 PM CDT Oct 19, 2019

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JASON: I GIVE HER A LOT OF CREDIT. MAX: THA IS WHY WE ARE HERE. JASON: IF YOU ARE RUNNING A MARATHON TOMORROW, YOU HAVE A BEAUTIFUL DAY FOR IT. 41 LIKE TO BE A LITTLE BIT COOL, BUT I KNOW A LOT OF PEOPLE CONSIDER THAT PERFECT RUNNING WEATHER. WE WILL CONTINUE WITH THE SUN SHINING INTO THE LATER PORTIONS OF THAT RUN. IF IT TAKES YOU PAST NOON TO 1:00, YOU HAVE A TEMPERATURE RUNNING UP TO 60 DEGREES. GOOD LUCK, RUNNERS, THE DAY IS NEARLY UPON YOU. THAT SUNSHINE HAS FELT GLORIOUS. THE RAIN EARLY ON HAS CLEARED OUT. A TEMPERATURE OF 60 RIGHT NOW. WE HAVE A BREEZE, COMFORTABLE AT FIVE MILES PER HOUR. STATEWIDE, SKIES ARE CLEAR. WE LOOK TO THE EAST. YOU CAN SEE A LITTLE BIT OF CLOUD COVER UP TOWARDS THE DEVON AREA -- DAVENPORT AREA. ALL THAT RAIN HAS MOVED EASTWARD WE HAVE ANOTHER SYSTEM BREWING OFF TO THE WEST. RAPID CITY TOWARD DENVER ARE BRINGING IN SNOW AND LIGHT RAIN. THAT WILL WORK IN OU DIRECTION TOWARDS LATER PORTIONS OF TOMORROW. MOST OF THE DAY TOMORROW IS LOOKING WONDERFUL. 65 FOR MINNEAPOLIS IF YOU ARE TRAVELING TO THE SOUTH. TEMPERATURES NEAR 70 FOR ST. LOUIS AND DODGE CITY. 60 DEGREES IS WHAT WE ARE LOOKING AT FOR THE START. DO HAVE A CHANCE AT AN ISOLATED SCATTERED SHOWER. THE BULK OF THE RAIN WILL BE MUCH LATER THAN 8:00 P.M.. CLEAR SKIES STICKING AROUND TONIGHT. SIX AND 7:00 IN THE MORNING, IT HAS PATCHY FOG. CLOUD COVER MAKES ITS WAY IN THE METRO, AREAS EASTWARD. 9:00 P.M., WE SEE A LINE OF SHOWERS WORKING TO THE EAST. 11:00, STRADDLING 35. WE HEAD INTO MONDAY. IT LOOKS TO BE CLOUDY AND DRIER. CHANCES OF ISOLATED SHOWERS THROUGH NORTHERN PORTIONS OF THE STATE. WE HANG ONTO THAT INTO THE MORNING HOURS TUESDAY. AS FAR AS HOW MUCH RAIN YOU C EXPECT, NOT A HUGE RAINMAKER. UNDER A QUARTER OF A INCH FOR THE ENTIRE STATE AS THE RAIN AND STORM ACTION MAKES ITS WAY THROUGH. TONIGHT, SEASONAL TEMPERATURES. 41 IS WHAT WERE TALKING. TOMORROW 64. R TH RAIN WILL BE MUCH LATER INTO THE EVENING HOURS. WE ARE HANGING ON TO LIGHT RAIN CHANCES SUNDAY AND MONDAY. AFTER THAT, WE ARE LOOKING DRY. 54 TUESDAY.

Storms expected to finish the weekend

Updated: 6:57 PM CDT Oct 19, 2019

Jason Sydejko brings the latest in KCCI weather.

Jason Sydejko brings the latest in KCCI weather.

Link:
Storms expected to finish the weekend - KCCI Des Moines

Update on the latest sports – FOX5 Las Vegas

MLB-ALCS

Astros strike early

HOUSTON (AP) Its a battle of the bullpens tonight as the Houston Astros try to beat the New York Yankees and win their second American League pennant in three years.

The Astros struck immediately as Yuli Gurriel (YOO-lee gur-ee-EHL) smacked a three-run homer with two out in the first inning. Jose Altuve (al-TOO-vay) laced a one-out double and Alex Bregman kept the inning alive with a two-out walk before Gurriel went deep off Green.

Houston still led, 3-0 heading into the second inning.

Managers AJ Hinch and Aaron Boone plan to go with their relievers for Game 6. Brad Peacock started for Houston against Chad Green. Both teams had their pitching rotations disrupted by Wednesdays rainout, causing the two clubs to play four straight games.

New York sent the series back to Houston with last nights 4-1 game, a game in which neither team scored after the first inning. The Astros had won three straight since dropping the series opener, 7-0.

Game 7 would be tomorrow in Houston if necessary. Houston will start a fully-rested Gerrit Cole, who is 19-0 in 25 starts since a loss to the White Sox back on May 22. The Yankees will counter with Luis Severino, who was the losing pitcher against Cole and the Astros in Game 3.

T25 FOOTBALL-SCHEDULE

Badgers stunned by Illini

UNDATED (AP) Unranked Illinois has authored one of the biggest top-25 upsets of the current college football season.

The Illini had been 2-5 overall and 0-3 in the Big Ten until James McCourt booted a 39-yard field as time expired to lift Illinois past sixth-ranked Wisconsin, 24-23. Tony Adams picked off a pass by Jack Coan at midfield with 2:33 remaining to spark the comeback.

Illinois entered the game as 30 -point underdogs against the Badgers, who never trailed in a game this season before squandering a nine-point lead over the final 9:46.

Heisman Trophy contender Jonathan Taylor rushed 28 times for 132 yards and one touchdown for Wisconsin, but he also had a fumble in Illinois territory in the fourth quarter to set up a 75-yard TD drive for the Illini.

In other Top 25 action:

Second-ranked LSU coasted to a 36-13 win over Mississippi State as Joe Burrow passed for 327 yards and four touchdowns. Burrows has a team-record 29 TD passes this season after going 25 of 32 for the 7-0 Tigers. LSU managed to score points on every drive of the first half and led 22-7 at the break.

Third-ranked Clemson coasted to its 22nd consecutive win as Travis Etienne (EE'-tee-ehn) rushed for 192 yards and a score in a 45-10 thumping of Louisville. Trevor Lawrence overcame two early interceptions to finish 20 of 29 for 233 yards and three touchdowns. Darien Rencher and Chez Mellusi added rushing TDs for the Tigers.

Fifth-ranked Oklahoma rolled to a 52-14 win against West Virginia as Jalen Hurts accounted for 391 total yards and five scores. Hurts threw for 316 yards and three TDs and also rushed for 75 yards and two touchdowns. The Sooners have scored at least 34 points in 17 straight games after racking up 562 yards of offense in their eighth straight win over the Mountaineers.

Kyle Trask threw three of his career-high four touchdowns in the fourth quarter to rally No. 9 Florida to a 38-27 victory at South Carolina. The Gamecocks led 20-17 in the final period until Trask scrambled for a first down and hit Lamical Perine for a 25-yard TD. The Gators bounced back from last weekends loss to LSU and knocked off a team that was coming off a victory against previous No. 3 Georgia.

Bo Nix passed for three touchdowns and ran for another as No. 11 Auburn routed Arkansas, 51-10. Nix turned a close game into a blowout by throwing two TDs in a span of 22 seconds in the third quarter.

Justin Herberts fourth scoring strike of the day was a five-yard throw to Jaylon Redd with 5:10 left to give No. 12 Oregon a 35-31 win against No. 25 Washington. The Ducks trailed 28-14 after Puca Nacua caught a 33-yard TD pass from Jacob Eason on the opening drive of the second half.

Charlie Brewer ran for a TD and was 13 of 17 passing for 312 yards and a touchdown in No. 18 Baylors 45-27 romp over Oklahoma State. JaMycal Hasty rushed for 139 yards and two touchdowns on 15 carries to help the Bears run their school-record winning streak to nine games.

Shane Buechele (boo-SHEHL) set career highs with six touchdown passes and 457 passing yards as No. 19 SMU hammered Temple, 45-21. Reggie Roberson Jr. had a career-high 250 receiving yards on seven catches, including touchdowns of 75, 75 and 33 yards for the 7-0 Mustangs.

No. 20 Minnesota is 7-0 for the first time since their 1960 national championship season after Rodney Smith ran for 111 yards and two touchdowns in a 42-7 thumping of Rutgers. Tanner Morgan threw two touchdowns as the Gophers won their ninth straight game since last season.

Gerrid Doaks ran for a pair of touchdowns and turned a short pass into a 28-yard score in helping No. 21 Cincinnati hold on for a 24-13 victory over Tulsa.

Riley Neal came off the bench and threw a 21-yard touchdown to Cam Johnson with 8:57 left to push Vanderbilt past No. 22 Missouri, 21-14.

Zac Thomas threw for 214 yards and three touchdowns and ran for another score as No. 24 Appalachian State had no trouble earning its first victory as a ranked team, 52-7 against Louisiana-Monroe 52-7.

No. 23 Iowa ended a two-game skid as Mekhi Sargent ran for a 14-yard score with 2:16 left in the Hawkeyes 26-20 triumph over Purdue.

NFL-TITANS-SIMMONS

Titans activate rookie Simmons

NASHVILLE, Tenn. (AP) The Tennessee Titans have activated first-round draft pick Jeffery Simmons, giving him a chance to make his NFL debut Sunday against the Los Angeles Chargers.

Tennessee made the 6-foot-4 Simmons its top pick after the defensive tackle from Mississippi State fell from a projected top 10 selection to 19. He tore his left ACL in February and was expected to miss the 2019 season. But Simmons recovered quickly and started practicing with the 2-4 Titans on Wednesday.

NBA-NEWS

Raptors, Siakam work out extension

UNDATED (AP) A person with knowledge of the situation says Pascal Siakam (see-A'-kam) and the Toronto Raptors have agreed on a four-year maximum extension that will be worth $130 million and begin next season.

Siakam was a breakout player last season for the NBA champions, averaging career highs of 16.9 points, 6.9 rebounds and 3.1 assists. He's entering his fourth season, and now is under contract to the Raptors through July 1, 2024.

In other NBA news:

The Hawks have exercised the 2020-21 contract options on forward John Collins and guards Trae Young and Kevin Huerter (HUR-tur). Collins led the Hawks with his averages of 19.5 points and 9.8 rebounds last season. Young was an NBA All-Rookie First Team selection after averaging 19.1 points and 8.1 assists. Huerter was a second team all-rookie pick after scoring 9.6 points per game.

NHL-SCHEDULE

Habs extend Blues skid

UNDATED (AP) The defending Stanley Cup champs find themselves in the midst of a four-game losing streak.

Brendan Gallagher, Jonathan Drouin (DROO-an) and Nick Suzuki scored in the second period to ignite the Canadiens in their third victory in four games, 5-2 at St. Louis. The game was tied until the Habs beat Jake Allen three times in the middle stanza, while Carey Price made 15 saves in the period.

Jordan Weal and Shea Weber also scored to back Price, who turned back 32 shots in his 325th career victory.

Elsewhere on NHL ice:

First overall pick Jack Hughes scored his first NHL goal and Mackenzie Blackwood posted his third career shutout by stopping 25 shots in the Devils 1-0 win over the Canucks. Hughes netted a power-play goal to help New Jersey earn its second straight win since a season-opening six-game losing streak.

NASCAR-KANSAS-QUALIFYING

Hemric beats playoff drivers for NASCAR pole at Kansas

KANSAS CITY, Kan. (AP) Daniel Hemric has the pole for Sundays NASCAR Cup playoff race at Kansas Speedway as he tries to land a full-time ride next year.

He turned a lap of 178.047 mph to edge the retiring David Ragan during Saturdays qualifying. Hemric was told last month by Childress Racing that the race team was passing on his 2020 option.

Ryan Blaney was third after his rain-delayed win last weekend at Talladega. Brad Keselwoski will start alongside him after qualifying fourth and Kyle Larson will start fifth. Blaney and Larson already have earned spots when the playoff field is cut to eight drivers on Sunday.

LPGA-SHANGHAI

Korda takes 1-shot lead with 6-under 66

SHANGHAI (AP) Jessica Korda carded eight birdies in a 6-under 66 that gives her a one-stroke lead through three rounds of the Buick LPGA Shanghai.

Fellow American Danielle Kang is alone in second following a 66 that included six birdies and an eagle.

Second-round leader Brooke Henderson dropped to third place, falling five strokes back with a double-bogey on her final hole.

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Update on the latest sports - FOX5 Las Vegas

Brooks Koepka Withdraws in Korea After Reaggravating Knee Injury – Golf Channel

Brooks Koepka withdrew before the start of the third round of the CJ Cup because of a knee injury.

This fall the world No. 1 underwent a stem-cell treatment to repair a partially torn patella tendon in his left knee. On Wednesday, Koepka told reporters that his knee feels good, but he said in a statement released through the PGA Tour communications department that he reaggravated the injury when he slipped on wet concrete during a second-round 75 Friday in Korea.

Koepka was supposed to play in next weeks inaugural Zozo Championship in Japan, but now, after consulting with his doctor, hes headed home to South Florida for further testing. He was the defending champion at the CJ Cup.

CJ Cup: Full-field scores | Full coverage

Koepka never revealed his knee issue until earlier this month in Las Vegas. He said that his knee had been bothering him since March, and that it limited his practice sessions and caused him pain every time he leaned down to grab the ball out of the cup.

Did my rehab, my recovery and there shouldnt be any issues, he said earlier this week. There might be one more round of stem cells before the end of the year, during some off time. But other than that, I feel great. My knee feels good. Its the first time its been feeling consistently good in a while.

Koepka missed the cut at the Shriners Hospitals for Children Openand now faces an uncertain rest of the calendar year.

Excerpt from:
Brooks Koepka Withdraws in Korea After Reaggravating Knee Injury - Golf Channel

New Gene Therapy Approach Reduces Cost and Improves Efficiency – DocWire News

A more efficient approach to gene therapy that could lower costs and improve patient outcomes has recently been developed by a team from Scripps Research. This work, published on October 17 in the journal Blood, offers a potential alternative to the standard process of delivering gene therapy, which is expensive, time-consuming, and requires many steps to administer healthy genes to the patients stem cells.

If you can repair blood stem cells with a single gene delivery treatment, rather than multiple treatments over the course of many days, you can reduce the clinical time and expense, which removes some of the limitations of this type of approach, explained research leader Bruce Torbett, PhD, associate professor in the Department of Immunology and Microbiology.

The goal of gene therapy is to introduce a healthy version of a gene to a patients stem cells to replace a defective copy of this gene. This approach is designed to treat inherited conditions caused by genetic mutations, such as sickle cell anemia. Patients with sickle cell have a mutation in a gene that codes for a protein in blood cells, leading to misshaped cells that cause a myriad of clinical issues. The goal of gene therapy is to replace this mutated gene with a healthy copy to restore normal protein synthesis and eliminate the disease symptoms. This is often done by implanting the healthy gene into a modified virus, known as a viral vector, and having this virus use its innate ability to infiltrate host cells and inject this healthy gene into them.

Gene therapy treatments typically require the harvesting of a small population of hemopoietic stem cells, the cells that serve as precursors for all types of blood cells, from the patients blood. Viral vectors containing therapeutic genes are then introduced to these cells with the goal being for them to insert this genetic information into the stem cells.

The hemopoietic stem cells defend themselves from viral penetrance using interferon-induced transmembrane (IFITM) proteins that block the viral vectors. For this reason, many gene therapies require a large number of vectors and many attempts for success, which is an expensive process.

In their work, the Scripps team focused on caraphenol A, a molecular relative of resveratrol, a natural compound made by grapes and other plants present in wine. Resveratrol is known to have antioxidant and anti-inflammatory properties. Although caraphenol A shares these anti-inflammatory properties, it served a much different purpose in this work.

Observing the chemical properties of resveratrol and associated molecules such as caraphenol A, Torbett and colleagues wanted to investigate whether they could be used in gene therapy to improve the viral vectors ability to enter blood stem cells. Enhancing viral vector penetrance into host cells would be advantageous, being that the cells natural defense mechanisms against viral attacks present a challenge in gene therapy.

This is why gene therapy of hemopoietic stem cells has been hit-or-miss, explained Torbett. We saw a way to potentially make the treatment process significantly more efficient.

The researchers found that by adding caraphenol A to human hemopoietic stem cells with the viral vector present, the stem cells defense was weakened, and the viral penetrance increased. When these treated stem cells were implanted into mice in this study, they were observed to produce blood cells that contained the new genetic information.

In addition to saving costs, this approach also cuts down the time required for a patient to receive a gene therapy treatment. Reducing treatment time is not only convenient for the patient, but it lowers the chance that the stem cells lose their self-renewing properties as well. The more time the stem cells spend being outside of the body and being manipulated, the higher the likelihood of them losing their proliferative ability is.

Torbetts team is continuing to research how stem cells combat viral attacks, hoping to lower the cost of gene therapy while improving efficiency.

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New Gene Therapy Approach Reduces Cost and Improves Efficiency - DocWire News

Injured Williamson to miss start of season | Sports | Journal Gazette – Fort Wayne Journal Gazette

New Orleans Pelicans forward Zion Williamsonwill be out weeks of the regular season because of a knee injury, according to ESPN.

He was scheduled to make his Madison Square Garden debut in Friday's preseason game against the New York Knicks but remained in New Orleans for treatment and tests.

The injury is reportedly not severe, butit's the same knee that Williamson sprained at Duke when his sneaker blew out. The other knee prompted him to abandon Summer League after playing just nine minutes.

Williamson had averaged 23.3 points on 71.4% shooting in four preseason games.

BASEBALL

Braves' star has elbow surgery

Atlanta first baseman Freddie Freeman underwent arthroscopic surgery on his right elbow after a nagging injury that limited him late in the season and into the playoffs. Freeman is expected to be recovered in time for the start of spring training in February.

COLLEGES

Second Spartan plans to transfer

Michigan State receiver Cam Chambers entered the transfer portal, the second Spartans receiver to make the move in less than a week. Chambers has played in only two games this season with no receptions. Earlier in the week, the school said wide receiver Weston Bridges was entering the transfer portal. He has not played in a game in 2019.

GOLF

PGA Tour suspends Every

Matt Every was suspended for three months for violating the PGA Tour's conduct policy on drugs of abuse. Every will be eligible to return Jan. 7. He will miss only three tournaments for which he would have been eligible.

Koepka exits Korean event

Top-ranked Brooks Koepka withdrew from the CJ Cup at Nine Bridges in Jeju Island, South Korea, with a knee injury following his second round, the PGA Tour said. Koepka had stem cell treatment on his left knee Aug. 25 after the FedEx Cup ended.

Roundup

In Jeju Island, South Korea, Justin Thomas shot a 9-under 63 to take a two-stroke lead at the CJ Cup at Nine Bridges, putting himself in position to win his second PGA Tour event in South Korea in three years. Thomas, who won the inaugural CJ Cup in 2017, had a two-round total of 13-under 131. South Korean-born New Zealander Danny Lee (66) was in a tie for second place with first-round leader Byeong Hun An, who shot 69. ...

In Richmond, Virginia, Tommy Tolles closed with a birdie for a 7-under 65 and the first-round lead in the Dominion Energy Charity Classic, the first of three tournaments in the Charles Schwab Cup playoffs. Colin Montgomerie and Scott Parel shot 66, and Miguel Angel Jimenez, Retief Goosen and Rocco Mediate were at 67. ...

In Shanghai, Brooke Henderson hit a hole-in-one and shot a tournament record 8-under 64 to take the lead in the second round of the Buick LPGA Shanghai. The Canadian hit her ace on the 144-yard second hole. She finished her round at 11-under 133 total. Jessica Korda (67) was two strokes behind in second, followed by defending champion Danielle Kang (67) in third.

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Injured Williamson to miss start of season | Sports | Journal Gazette - Fort Wayne Journal Gazette