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Induced Pluripotent Stem Cells (iPSCs)

Initially described in the pioneering work of Yamanaka and colleagues, the ability to "reprogram" differentiated somatic cells into a pluripotent embryonic stem cell-like state by retroviral mediated expression of four specific transcription factors has revolutionized our ability to develop new models to study human disease and represents a significant step towards patient-specific cell replacement therapies.

In addition to solving ethical concerns related to the use of blastocyst-derived embryonic stem cells, the use of iPSCs for the generation of therapeutic cells for cell replacement therapy may avoid the requirement for post-transplant immune suppression because iPSCs can be generated directly from the transplant recipient and will therefore be genetically identical to the patient. Additionally, because it is possible to reprogram somatic cells derived from diseased individuals iPSC technology provides an important new platform for the development of new models of human disease. Thus, upon appropriate differentiation these cells can then be used to study normal and pathologic human tissue development in vitro, enabling new insights into disease pathology as well as a platform for the development of novel therapeutic agents and patient-specific cell replacement therapies.

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Induced Pluripotent Stem Cells (iPSCs)

Human Induced Pluripotent Stem Cells – Cell Applications

Integration-free HiPSC.Our HiPSC are generated with the RNA-based Sendai virus to deliver reprogramming factors to donor skin fibroblasts. Since the virus does not go through a DNA phase, its genetic material and transgenes do not integrate into the host cell genome. HiPSC are validated for viability, karyotype, pluripotency, plating efficiency, morphology, passage number and lack of contamination.

HiPSC-derived Neural Stem Cells (L) and Neurons (R). i-HNSC stained w/ Nestin (neural stem cell marker, green), SOX 2 (stem cell marker, red) & DAPI (nuclear stain, blue). SOX2 & DAPI nuclear co-localization yields purple (Left). Video: Human iPSC-Derived Neurons establish mature, synchronized neuronal network. In real time, Multi-electrode array (MEA) shows optimal electrophysiological activity, which can be modulated by neurotransmitters or small compounds (Right).

HiPSC-derived Cardiomyocytes (i-HCM) plated onto a flat culture surface pulsate in vitro (L), while iHCM printed into 3D heart tissue using a Cyfuse Regenova also beat (R)

Reprogrammingtriggers a cascade of evident changes in the host cells that are recognizable morphologically and through a combination of markers and pluripotency assays. Our HiPSCs display classic pluripotent stem cell morphology, with a high nucleus to cytoplasm size ratio, as well as they are amenable to be cultivated in serum-free media, independent of feeder cells and of feeder-conditioned media as colonies or high density monolayers. hiPSCs are also evaluated for the presence of karyotypic abnormalities. Confirmation of pluripotency is performed through the analysis of expression of several established independent pluripotency markers. Unguided differentiation confirms HiPSC ability to generate cell derivatives of tissues arising from the three embryonic layers.

Cell Characterization. Post-thawing viability of HiPSCs is typically higher than 70%, and HiPSC have demonstrated coherent pluripotent behavior over more than 60 passages. Although it is in theory possible to propagate HiPSCs indefinitely, HiPSC subculturing over passages higher than is usually not recommended, as the chances of karyotypic abnormalities increase. HiPSCs are also tested to ensure absence of microorganism contaminants.

For Research Use Only - Not for Human or Clinical Applications

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Human Induced Pluripotent Stem Cells - Cell Applications

Stem Cell Therapy and Stem Cell Injection Provider Finder …

Stem cell therapy can be described as a means or process by which stem cells are used for the prevention, treatment or the cure of diseases. Stem cells are a special kind of cells that have features other types of cells dont have. As an illustration, stem cells are capable of proliferation. This implies that they can develop into any type of cell, and grow to start performing the functions of the tissue. In addition, they can regenerate. This means they can multiply themselves. This is most important when a new tissue has to be formed. Also, they modulate immune reactions. This has made them useful for the treatment of autoimmune diseases, especially those that affect the musculoskeletal system such as rheumatoid arthritis, systemic lupus erythematosus and so on. Stem cells can be derrived from different sources. They can be extracted from the body, and in some specific parts of the body. This includes the blood, bone marrow, umbilical cord in newborns, adipose tissue, and from embryos. There are 2 main types of stem cell transplant. These are autologous stem cell transplant, and allogeneic stem cell transplant. The autologous stem cell transplant means that stem cells are extracted from the patient, processed, and then transplanted back to the patient, for therapeutic purposes. On the other hand, allogeneic stem cell transplant means the transplant of stem cells or from another individual, known as the donor, to another person, or recipient. Some treatments must be given to the receiver to prevent any cases of rejections, and other complications. The autologous is usually the most preferred type of transplant because of its almost zero side effects. Below are some of the stem cell treatments. Our goal is to provide education, research and an opportunity to connect with Stem Cell Doctors, as well as provide stem cell reviews

Adipose Stem Cell TreatmentsAdipose stem cell treatment is one of the most commonly used. This is because large quantities of stem cells can be derrived from them. According to statistics, the number of stem cells in adipose tissue are usually hundreds of times higher than what can be obtained from other sources, such as the bone marrow stem cells. Adipose stem cells have taken the center stage in the world of stem cell therapy. Apart from the ease that comes with the harvesting of these cells from the adipose tissue, they also have some special features, that separates them from other types of cells. Adipose stem cells are capable of regulating and modulating the immune system. This includes immune suppression, which is important for the treatment of autoimmune diseases. In addition, adipose stem cells can differentiate to form other types of cells. Some of them include the bone forming cells, cardiomyocytes, and cells of the nervous system.

This process can be divided into four parts. These are

Stem cell joint injection is fast becoming the new treatment of joint diseases. Stem cells derived from bone marrow, adipose and mesenchymal stem cells are the most commonly used. The stem cells are injected into the joints, and they proceed to repair and replace the damaged tissues. The cells also modulate the inflammatory process going on. Overall, stem cell joint injections significantly reduce the recovery time of patients and also eliminates pain and risks associated with surgery. Examples of diseases where this treatment is used include osteoarthritis, rheumatoid arthritis, and so on. Researchers and physicians have rated this procedure to be the future of joint therapy.

Losing a tooth as a kid isnt news because youd eventually grow them back, but losing one as an adult isnt a pleasant experience. Youd have to go through the pains of getting a replacement from your dentist. Apart from the cost of these procedures, the pain and number of days youd have to stay at home nursing the pain is also a problem. Nevertheless, there are great teeth replacement therapies available for all kinds of dental problems. Although there are already good dental treatment methods, stem cell therapy might soon become the future of dental procedures. Currently, a lot of research is being done on how stem cells can be used to develop teeth naturally, especially in patients with dental problems. The aim of the project is to develop a method whereby peoples stem cells are used in regenerating their own teeth and within the shortest time possible. Some of the benefits of the stem cell tooth would be:

The quality of life of those that underwent serious procedures, especially those that had an allogeneic hematopoietic stem cell transplantation done was studied. It was discovered that this set of people had to cope with some psychological problems, even years after the procedure. In addition, allogeneic stem cell transplantation often comes with some side effects. However, this a small price to pay, considering that the adverse effects are not usually life-threatening. Also theses types of procedures are used for severe disorders or even terminal diseases. On the other hand, autologous stem cell transplantation bears the minimum to no side effects. Patients do have a great quality of life, both in the short term and in the long term.

This is one of the many uses of stem cells. The stem cell gun is a device that is used in treating people with wounds or burns. This is done by simply triggering it, and it sprays stem cells on the affected part. This kind of treatment is crucial for victims of a severe burn. Usually, people affected by severe burns would have to endure excruciating pain. The process of recovery is usually long, which might vary from weeks to months, depending on the severity of the burn. Even after treatment, most patients are left with scars forever. However, the stem cell gun eliminates these problems, the skin can be grown back in just a matter of days. The new skin also grows evenly and blends perfectly with the other part of the body. This process is also without the scars that are usually associated with the traditional burns therapy. The stem cell gun is without any side effects.

There is one company that focuses on the production of stem cell supplements. These stem cells are usually natural ingredients that increase the development of stem cells, and also keeps them healthy. The purpose of the stem cell supplements is to help reduce the aging process and make people look younger. These supplements work by replacing the dead or repairing the damaged tissues of the body. There have been a lot of testimonials to the efficacy of these supplements.

It is the goal of researchers to make stem cell therapy a good alternative for the millions of patients suffering from cardiac-related diseases. According to some experiments carried out in animals, stem cells were injected into the ones affected by heart diseases. A large percentage of them showed great improvement, even within just a few weeks. However, when the trial was carried out in humans, some stem cells went ahead to develop into heart muscles, but overall, the heart function was generally improved. The reason for the improvement has been attributed to the formation of new vessels in the heart. The topic that has generated a lot of arguments have been what type of cells should be used in the treatment of heart disorders. Stem cells extracted from the bone marrow, embryo have been in use, although bone marrow stem cells are the most commonly used. Stem cells extracted from bone marrow can differentiate into cardiac cells, while studies have shown that other stem cells cannot do the same. Even though the stem cell therapy has a lot of potential in the future, more research and studies have to be done to make that a reality.

The use of stem cells for the treatment of hair loss has increased significantly. This can be attributed to the discovery of stem cells in bone marrow, adipose cells, umbilical cord, and so on. Stem cells are extracted from the patient, through any of the sources listed above. Adipose tissue stem cells are usually the most convenient in this scenario, as they do not require any special extraction procedure. Adipose tissue is harvested from the abdominal area. The stem cells are then isolated from the other cells through a process known as centrifugation. The stem cells are then activated and are now ready for use. The isolated stem cells are then introduced into the scalp, under local anesthesia. The entire process takes about three hours. Patients are free to go home, after the procedure. Patients would begin to see improvements in just a few months, however, this depends largely on the patients ability to heal. Every patient has a different outcome.

Human umbilical stem cells are cells extracted from the umbilical cord of a healthy baby, shortly after birth. Umbilical cord tissue is abundant in stem cells, and the stem cells can differentiate into many types of cells such as red blood cells, white blood cells, and platelets. They are also capable of differentiating into non-blood cells such as muscle cells, cartilage cells and so on. These cells are usually preferred because its' extraction is minimally non invasive. It also is nearly painless. It also has zero risks of rejecting, as it does not require any form of matching or typing.Human umbilical stem cell injections are used for the treatment of spinal cord injuries. A trial was done on twenty-five patients that had late-stage spinal cord injuries. They were placed on human umbilical stem cell therapy, while another set of 25 patients were simultaneously placed on the usual rehabilitation therapy. The two groups were studied for the next twelve months. The results of the trial showed that those people placed on stem cell therapy by administering the human umbilical cell tissue injections had a significant recovery, as compared to the other group that underwent the traditional rehabilitation therapy. It was concluded that human umbilical tissue injections applied close to the injured part gives the best outcomes.

Stem cell therapy has been used for the treatment of many types diseases. This ranges from terminal illnesses such as cancer, joint diseases such as arthritis, and also autoimmune diseases. Stem cell therapy is often a better alternative to most traditional therapy today. This is because stem cell procedure is minimally invasive when compared to chemotherapy and so on. It harnesses the bodys own ability to heal. The stem cells are extracted from other parts of the body and then transplanted to other parts of the body, where they would repair and maintain the tissues. They also perform the function of modulating the immune system, which makes them important for the treatment of autoimmune diseases. Below are some of the diseases that stem cell therapies have been used successfully:

A stem cell bank can be described as a facility where stem cells are stored for future purposes. These are mostly amniotic stem cells, which are derived from the amnion fluid. Umbilical cord stem cells are also equally important as it is rich in stem cells and can be used for the treatment of many diseases. Examples of these diseases include cancer, blood disorders, autoimmune diseases, musculoskeletal diseases and so on. According to statistics, umbilical stem cells can be used for the treatment of over eighty diseases. Storing your stem cells should be seen as an investment in your health for future sake. Parents do have the option of either throwing away their babys umbilical cord or donating it to stem cell banks.

The adipose tissue contains a lot of stem cells, that has the ability to transform into other cells such as muscle, cartilage, neural cells. They are also important for the treatment of some cardiovascular diseases. This is what makes it important for people to want to store their stem cells. The future health benefit is huge. The only way adults can store their stem cells in sufficient amounts is to extract the stem cells from their fat tissues. This process is usually painless and fast. Although, the extraction might have to be done between 3 to 5 times before the needed quantity is gotten. People that missed the opportunity to store their stem cells, using their cord cells, can now store it using their own adipose tissues. This can be used at any point in time.

Side effects often accompany every kind of treatment. However, this depends largely on the individual. While patients might present with side effects, some other people wouldnt. Whether a patient will present with adverse effects, depends on the following factors;

Some of the common side effects of stem cell transplant are;

Stem cell treatment has been largely successful so far, however, more studies and research needs to be done. Stem cell therapy could be the future.

Stem cells are unique cells that have some special features such as self-regeneration, tissue repair, and modulation of the immune system. These are the features that are employed in the treatment of diseases.

Our doctors are certified by iSTEMCELL but operate as part of a medical group or as independent business owners and as such are free to charge what the feel to be the right fit for their practice and clients. We have seen Stem Cell Treatment costs range from $3500 upwards of $30,000 depending on the condition and protocol required for intended results. Find the Best Stem Cell Doctor Near me If you are interested in saving money, try our STEM CELL COUPON!

Travel Medcations are becoming very popular around the globe for several reasons but not for what one might think. It is not about traveling to Mexico to save money, but to get procedures or protocols that are not yet available in your home country. Many procedures are started in your home country, then the tissue is set to the tissue lab where it is then grown in a process to maximize live cells, then sent to a hospital in Mexico designed to treat or provide different therapies for different conditions. If you're ready to take a medical vacation call 972-800-6670 for our"WHITE GLOVE" service.

Chen, C. and Hou, J. (2016). Mesenchymal stem cell-based therapy in kidney transplantation. Stem Cell Research & Therapy, 7(1).

Donnelly, A., Johar, S., OBrien, T. and Tuan, R. (2010). Welcome to Stem Cell Research & Therapy. Stem Cell Research & Therapy, 1(1), p.1.

Groothuis, S. (2015). Changes in Stem Cell Research. Stem Cell Research, 14(1), p.130.

Rao, M. (2012). Stem cells and regenerative medicine. Stem Cell Research & Therapy, 3(4), p.27.

Vunjak-Novakovic, G. (2013). Physical influences on stem cells. Stem Cell Research & Therapy, 4(6), p.153.

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Stem Cell Therapy and Stem Cell Injection Provider Finder ...

Patient Application Disclaimer – Stem Cell Institute

Click the YES button at the bottom of this page to continue.

This website http://www.cellmedicine.com offers patients, doctors and scientists the opportunity to connect to licensed doctors who use adult stem cells as part of their clinical practice outside of the United States and Canada. Because stem cell therapy is not the standard of care in the US or Canada, the following important disclosures are made:

The science of treatment with adult stem cells is in its infancy.

The treatments described on cellmedicine.com have not been evaluated by the US FDA and are not considered to be standard of care for any condition or disease.

There could be significant and unknown risks associated with adult stem cell treatments, as long-term studies have not been performed.

For most diseases no prospective, randomized clinical trials of adult stem cells have been performed, therefore no guarantee of safety or effectiveness is made or implied.

Treatments by licensed doctors will only be performed after the patient understands and agrees to informed consent.

The results of testimonials of people who appear on this website who have undergone stem cell treatment are not necessarily typical.

If you are accepted for treatment by a doctor, the treatment will not be performed in the USA or Canada. It will be performed in Panama City, Panama.

Applications take up to 5 working days to review from the first working day they are received.

This is not a clinical trial.

Health insurance will not cover the treatment fees.

The Stem Cell Institute does not provide itemized bills.

Treatments include from3 to 16 separate stem cell infusions/injectionsover the course of 4 to 30 days depending upon the protocol employed. A fee will be quoted once your treatment protocol has been determined.

To access the application you must first agree that you have read and understand all of the statements above.

I have read and understand all of the statements above:

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Patient Application Disclaimer - Stem Cell Institute

Knee Stem Cell Therapy – Vermont Regenerative Medicine

Knee Stem Cell TherapyVermont Regenerative Medicine2017-08-07T18:22:10+00:00 Regenexx Advanced Knee Stem Cell Therapy and Platelet Rich Plasma Procedures for Common Knee Injuries and Knee Osteoarthritis

Regenexx Knee Stem Cell Therapy and Platelet Procedures are breakthrough, non-surgical treatments for people suffering from knee pain due to common injuries to the knee meniscus, ACL or MCL, cartilage, or who are experiencing degenerative conditions, such as osteoarthritis. Traditional options for patients suffering from these conditions include arthroscopic knee surgery to repair ligament tears, or total knee joint replacement. With both surgeries, months of rehab are required, and the patient must be aware of and prepared to take on the risks. As an alternative, the Regenexx Stem Cell Procedure, or Regenexx Super Concentrated Platelet Rich Plasma Procedure may help alleviate knee pain and the conditions that cause it with a simple office injection procedure.

This Regenexx bone marrow derived stem cell treatment outcome data analysis is part of the Regenexx data download of patients who were tracked in the Regenexx advanced patient registry.

This Regenexx bone marrow derived stem cell treatment outcome data analysis is part of the Regenexx data download of patients who were tracked in the Regenexx advanced patient registry following treatment for Meniscus Tears.

This data utilizes LEFS (Lower Extremity Functional Scale) data from our knee arthritis patients treated with stem cell injections. Functional questionnaires ask the patients questions such as how well they can walk, run, climb stairs, etc. The improvements following the Regenexx Stem Cell Procedure are highly statistically significant.

Regenexx has published more data on stem cell safety in peer reviewed medical research for orthopedic applications than any other group world-wide. This is a report of 1,591 patients and 1,949 procedures treated with the Regenexx Stem Cell Procedure. Based on our analysis of this treatment registry data, the Regenexx Stem Cell Procedure is about as safe as any typical injection procedure, which is consistent with what we see every day in the clinic.

Stem Cells are in all of us and they are responsible for healing injured bone, ligaments, tendons and tissues. They are the key component behind the Regenexx Procedures. As we get older or injured, we sometimes cannot get enough of these cells into the area in need. The Regenexx Procedures help solve that problem by precisely delivering a high concentration of stem cells and growth factors into the injured area, aiding your bodys ability to heal naturally. Patients typically avoid the long, painful rehabilitation periods to restore joint strength and mobility following surgery. Regenexx patients are usually encouraged to walk the same day, and most experience little or no down-time from the procedure.

If you are suffering from pain due to an injury, degenerative condition, or prior surgery, you may be a good candidate for this ground-breaking treatment. Please complete the Candidate Form below and you will immediately receive more detailed information on the procedure, along with next steps in determining whether this procedure is right for you. Completion of this form does not constitute a patient/physician relationship.

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Knee Stem Cell Therapy - Vermont Regenerative Medicine

Stem Cell Therapy / drcalapai.net

Stem cells are unquestionably some of the most amazing cells in the human body. These are undifferentiated cells that do not have a direct blueprint or specific destiny. They can become differentiated into specialized cells anywhere throughout the body. They are classified as 2 different types of cells, those that are from embryonic origin and those called adult stem cells.

In the developing embryo, these cells differentiate into ectoderm, endoderm, and mesoderm. These give us rise to our spine, nerves, and all our organs. Adult stem cells are primarily used to repair, replenish, and regenerate tissues.

Historically, stem cells can come from a variety of tissues. These include umbilical cord, fetal tissue, adipose, or the best source bone marrow.

Bone marrow stem cells have the highest numbers of cells when collected and tested compared to all others. This is by far the preferred method of stem cell therapy because of sheer numbers and the fact that they are coming from your own body. This is called autologous therapy.

Stem cell research worldwide goes back over 100 years, the German research is documented back to 1860. There are a wide range of studies and articles describing its dramatic benefit for chronic diseases. Many of these publications are available for you to read on my website.

In performing stem cell therapy, extremely strict guidelines must be followed in coordination with a specialized protocol. This ensures accuracy, sterility, and quality control of the procedure. This information gathered from the procedure, including various forms of documentation can be used for medical publication at a later date. Physician notes and procedure as well as a questionnaire filled out by patients periodically are part of this process. This enables the highest level of procedure and documentation possible.

Initially, patients are examined, appropriate blood or other testing is done and reviewed and schedule is made to begin procedure. Typically, stem cell therapy is done within 2 weeks of initial consultation.

On the day of procedure, stem cells are extracted from Bone Marrow, this takes 5-10 minutes then patients sit and relax while the processing is done. It is then washed and centrifuged 3 times to allow separation of cells and harvest stem cells. At the end of the procedure, microscopic analysis can estimate the number of stem cells available for injection. Injection can be done either into joint, connective tissue, muscle or for all other organs or systemic diseases, intravenously. Intranasal technique also used for MS, Parkinsons, and Alzheimers disease. Intravenous and nebulizer is used for COPD, Emphysema, and Pumonary Fibrosis.

Research shows the therapy may benefit the following:

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered mainstream. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

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Stem Cell Therapy / drcalapai.net

Understanding Adult and Embryonic Stem Cell Research

Stem cell research is a complicated and controversial issue. Before you can be for it or against it, you must fully understand the terminology, the potential, and consequences of stem cell research. There are implicit details which shape the perception of stem cell research. It's been made a:

In mid-May 2005 President Bush said, "I am a strong supporter of stem cell research, but I've made it very clear to Congress that the use of federal taxpayer money to promote science that destroys life in order to save life, I am against this."

What are stem cells (SC)?

SC differ from other kinds of cells in the body. Regardless of their source, they are capable of dividing and renewing themselves for long periods. Although they are unspecialized, they can give rise to specialized types of cells (i.e. muscle, red blood, brain).

What are embryonic stem cells (ESC)?

ESC are derived from embryos that develop from eggs that have been fertilized in vitro, in an in vitro fertilization clinic. They are donated for research purposes with informed consent of the donors. They are not derived from eggs fertilized in a woman's body - a common misconception.

What are adult stem cells (ASC)?

ASC are undifferentiated, found among differentiated cell types in a tissue or organ. ASC can renew themselves, and can differentiate to yield the major specialized cell types of the tissue or organ. Their primary role in a living organism is to maintain and repair the tissue in which they are found.

How are ESC and ASC similar and how are they different?

They differ in the number and type of differentiated cells they can become. ESC can become all types found in the body. ASC are said to be less versatile, generally limited to differentiating into different cell types of their tissue of origin. However, other evidence suggests that an ASC from one adult tissue may be able to generate the differentiated types of cells of another adult tissue.

Continuing research on human embryonic stem cells could identify how undifferentiated stem cells become differentiated. It is known that turning genes on and off is central to the process. Some of the most serious medical conditions are caused by abnormal cell division and differentiation.

Better understanding of how these processes are controlled at the genetic and molecular level may lead to:

Simply put, those who support human embryonic stem cell research believe it could lead to possible cures for many diseases, including:

Human stem cells could also be used to test new drugs. According to the NIH (National Institutes of Health, "to screen drugs effectively, the conditions must be identical when comparing different drugs. Therefore, scientists will have to be able to precisely control the differentiation of stem cells into the specific cell type on which drugs will be tested. Current knowledge of the signals controlling differentiation fall well short of being able to mimic these conditions precisely to consistently have identical differentiated cells for each drug being tested."

The need for transplantable tissues and organs far outweighs the available supply. Stem cells, directed to differentiate into specific cell types, could offer the possibility of a renewable source of replacement cells and tissues to treat many diseases.

One of the main objections to embryonic stem cell research has to do with the belief that using embryos tampers with life. People who stand strong behind this ideology believe that even for the purpose of medical research and the possibility of saving lives, it is wrong. For people who oppose embryonic stem cell research it is a matter of ethics and morals which outweigh the scientific potential.

There is no guarantee that forging ahead with embryonic stem cell research will produce the desired results. That, too, is a problem for some who oppose it. The utilization of embryonic stem cells, is at this point theoretical, unlike adult stem cells which have shown therapeutic results.

Understanding this issue before formulating an opinion is imperative. Stem cell research is a complicated issue, without doubt. Further investigation regarding the scientific and ethical viewpoints can only result in being more informed and knowledgeable, and the assurance that you are standing on the side of the issue which most strongly aligns with your beliefs.

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Understanding Adult and Embryonic Stem Cell Research

Stem Cell Therapy | Stem Cell Doctors | Regenerative Medicine

At Stem Cell Doctors Treatment Centers we provide consultations relating to clinical researchand deployment of stem cell therapyfor patients suffering from diseases that may have limited treatment options.

Stem cell therapy is not for everyone but under the right circumstances and under the right conditions there may be an opportunity for stem cell therapy to be effective. But stem cell therapy is not, at present time, is not the holy grail we all would like it to be.

Our expertise involves a deep commitment and long-term understanding, knowledge and experience in clinical research and the advancement of regenerative medicine.

We firmly support respected guidance regarding stem cell therapy indicating that it should be autologous, include ONLY minimal manipulation of regenerative cells, and be consistent with homologous use.

We believe that treatment protocols ought to be reviewed and approved.

Because we are committed to the principles and ideals of regenerative medicine, we are continuously updating, researching, and learning more on how to help patients and advance the state of the art of regenerative medicine.

Accordingly we provide all patients who are interested in considering stem cell therapy an honest opinion as to the potential benefits and risks of stem cell therapy for their presenting condition.

At Stem Cell Doctors Treatment Centers we will review your medical records and condition, and then consider an array of ongoing IRB-approved protocols,to provide patients with a wide variety of treatment options and considerations for medical disorders that may benefit from adult stem cell-based regenerative therapy.

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Stem Cell Therapy | Stem Cell Doctors | Regenerative Medicine

Dr. Christopher Calapai D.O. – Dr. Calapai’s Nutritional …

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered mainstream. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

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Dr. Christopher Calapai D.O. - Dr. Calapai's Nutritional ...

Stem Cell Treatment for Cerebral Palsy – Beike Biotechnology

Nerve Growth Factor (NGF)

Nerve growth factor (NGF) is a member of the neurotrophic factor (neurotrophin, NTFS) family, which can prevent the death of nerve cells and has many features of typical neurotransmitter molecules. NGF plays an important role in the development and growth of nerve cells. NGF is synthesized and secreted by tissues (corneal epithelial, endothelial, and corneal stromal cells), and it can be up-taken by sympathetic or sensory nerve endings and then transported to be stored in neuronal cell bodies where it can promote the growth and differentiation of nerve cells.

NGF can exert neurotrophic effects on injured nerves and promote neurogenesis (the process of generating neurons from stem cells) that is closely related to the development and functional maintenance and repair of the central nervous system. It is also capable of promoting the regeneration of injured neurons in the peripheral nervous system, improving the pathology of neurons and protecting the nerves against hypoxia (lack of oxygen)/ischemia (lack of blood supply).

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Stem Cell Treatment for Cerebral Palsy - Beike Biotechnology