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Stem cell therapy for pets available in Huntsville

HUNTSVILLE, Ala. (WAAY) -- We hate to see our elderly loved ones start having trouble getting around. The same goes for our pets. They're part of the family too. Now there's a procedure that could help pets across the valley, in just one day.

For Tasha, Wednesday was a big day. The 12 year old black lab has a tough time getting around. She has hip dysplasia and arthritis. But this visit to Whitesburg Animal Hospital, should change that.

"In a week, they're better. Even in the first day or two, you'll see noticeable improvement," says Whitesburg veterinarian Dr. Mark Russell.

The hospital teamed up with MediVet America to offer a one-day stem cell procedure, the first in North Alabama. It can now activate sleeping stem cells in an animal's fat, then inject them right back into the damaged areas.

"The stem cells will repair and regenerate cartilage, tendons, whatever is lacking in that area," says Trey Smith, the Director of Lab Services for MediVet America.

In the past, the cells had to be sent to California to be activated. This quicker procedure has another benefit.

"We've relied on medications to try to control this, and that's pretty much all we had. And you get to a certain point, when the medication doesn't work anymore, and their quality of life is bad. That's not hardly worth it for them. This gives them a whole new option," Dr. Russell says.

"Probably 20 to 25 percent of dogs are arthritic and they're not very good at telling their owner they're hurting," adds Smith.

So, what should you look for?

Russell says, "When your pet starts slowing down, it may not be because they're getting older, it may be because they're hurt."

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Stem cell therapy for pets available in Huntsville

Seattle Genetics Seeks Expanded Use of Lymphoma Drug Following Study Win

SEATTLE ( TheStreet) -- Seattle Genetics (SGEN) will seek to expand the approved use of its Hodgkin lymphomadrug Adcetris following positive results from a phase III study, the company announced Monday.

In the study (known as AETHERA), treatment with Adcetris in "high risk" Hodgkin lymphomapatients immediately after a stem-cell transplant led to a 43% reduction in the risk of disease progression compared to placebo. The result was statistically significant and met the primary endpoint of the study.The Hodgkin lymphoma patients enrolled in the study were deemed to be "high risk" because they had at least one factorthat made them more susceptible to disease relapse.

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Despite delaying disease progression, treatment with Adcetris did not prolong survival compared to placebo in the phase III study at this analysis, which the company blames partly on placebo patients "crossing over" to receive Adcetris once their disease progressed. Another survival analysis of the study will be conducted in 2016. Adcetris' safety profile was "generally consistent" with previous studies, the company said. No further details were disclosed, pending presentation of the results at a future medical meeting.

Adcetris is already approved to treat more advanced Hodgkin patients who don't respond to a stem cell transplant or who are not eligible for stem cell transplants. Seattle Genetics plans to submit the results from the AETHERA trial to the FDA, seeking approval to expand the drug's use.

Seattle Genetics estimates there are about 1,000 to 1,500 post-transplant Hodgkin lymphoma patients. This represents a modest increase in the number of patients eligible for Adcetris and not as significant a commercial opportunity as treating newly diagnosed Hodgkin lymphoma patients. Studies investigating Adcetris' role in front-line Hodgkin are underway but not yet completed.

Seattle Genetics shares are up 4% to $43 in Monday pre-market trading.

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Seattle Genetics Seeks Expanded Use of Lymphoma Drug Following Study Win

Brain Repair 'May Be Boosted By Curry Spice'

A spice commonly found in curries may boost the brain's ability to heal itself, according to a report in the journal Stem Cell Research and Therapy.

The German study suggests a compound found in turmeric could encourage the growth of nerve cells thought to be part of the brain's repair kit.

Scientists say this work, based in rats, may pave the way for future drugs for strokes and Alzheimer's disease.

But they say more trials are needed to see whether this applies to humans.

Spice injection

Researchers from the Institute of Neuroscience and Medicine in Julich, Germany, studied the effects of aromatic-turmerone - a compound found naturally in turmeric.

Rats were injected with the compound and their brains were then scanned.

Particular parts of the brain, known to be involved in nerve cell growth, were seen to be more active after the aromatic-turmerone infusion.

Scientists say the compound may encourage a proliferation of brain cells.

In a separate part of the trial, researchers bathed rodent neural stem cells (NSCs) in different concentrations of aromatic-tumerone extract.

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Brain Repair 'May Be Boosted By Curry Spice'

Revolutionary treatment to extend Goodes' career?

Sydney Swans star Adam Goodes is reportedly set to undergo revolutionary stem cell treatment in a bid to prolong his AFL career.

According to News Corp, Goodes has requested the treatment on his troublesome right knee after also undergoing the procedure in January.

He wants to do it again, Swans medico Dr Nathan Gibbs.

Its saved his career. He would have retired a year ago.

Speculation has mounted that Goodes will hang up the boots after Sydneys humiliating loss in the AFL grand final against Hawthorn.

The fire still burns ... It can't help but burn after that loss.

The 34-year-old was among very few Sydney players who played well in the shock defeat.

He hurt his right knee in the grand final 2012 which damaged joint surface, then he damaged the cartilage in the same knee against Port last year, Gibbs said.

Goodes looks shattered after the grand final. Source: Getty

It was terrible because it was the last thing he needed. The surface damage of his knee was extensive, the medial and lateral sides were pretty bad and he just couldnt recover from it.

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Revolutionary treatment to extend Goodes' career?

Def Leppard's Vivian Campbell Addresses His Stem Cell Treatment Recap

Campbell was diagnosed with the cancer in 2013, which briefly went into remission only to return again. He received further treatment and cancer is once again in remission and he will be undergoing the stem cell transplant in an attempt to keep the cancer from returning once again.

He wrote on the band's official website, "As many of you know, I've been scheduled to start a stem cell transplant and as soon as I got home from tour I began the necessary tests and preparations. I'll be admitted to hospital soon for all the yucky bits, so in the meantime I'm headed to Target to stock up on cozy pajamas, fresh underwear, and a sackful of car-porn.

"Unfortunately, this means that I won't be able to perform with the band on the upcoming NFL broadcast on Sept. 28th, nor will I be able to do the shows scheduled for Oct/Nov.

"While I can't say that I'm looking forward to the process ahead, I'm very much looking forward to what I feel will be a most successful outcome. Next year will be very busy for Def Leppard with a new album and a world tour, and frankly, I don't think they would sound as loud without me, so I have no intention of letting the team down!

"See you all (with hair!) in 2015. - Viv" -

...end

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Def Leppard's Vivian Campbell Addresses His Stem Cell Treatment Recap

Def Leppard's Vivian Campbell Having Stem-Cell Surgery Recap

Campbell is officially in remission for the second time and will be receiving the treatment in hopes that it will prevent the cancer from returning. Elliot told Las Vegas radio station KOMP 92.3's '92 Minutes of Hair With Mel' show (via Loudwire), "Vivian, for the second time, is now in remission.

"The first time we were told he was in remission and he was, but it didn't take. It didn't stay; it came back. But this time, through clever management with his doctors, they were able to monitor him through the whole tour, so he could do the tour with KISS this summer."

Elliot went on to say, "As we speak, he's getting ready to go in to have stem-cell surgery, which will hopefully get rid of this thing once and for all. So, up until Christmas, he's gonna be kind of out of action, because once they start on this, they have to keep him so locked down and away from germs and stuff.

"I think anybody visiting him has to put on one of those nuclear suits. He'll be locked away and he'll be the boy in the bubble, but he's very confident that he can do this and his spirits are great."

There is no word is Vivian will be joining the band this Sunday when they perform the pregame show at the NFL game between The Oakland Raiders and the Miami Dolphins in London.

Elliott had this to say about the show, "Having most recently visited Wembley in May to watch Sheffield United in the FA Cup semi-final, I know what the atmosphere in the ground is like for 'our' football so I'm really looking forward to performing there before the NFL game and of course soaking up the excitement of the actual match. I can't wait!"

Listen to the full interview at Loudwire - here.

...end

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Def Leppard's Vivian Campbell Having Stem-Cell Surgery Recap

Common Curry Ingredient Could Help The Brain Battle The Affects Of Alzheimers

September 27, 2014

Chuck Bednar for redOrbit.com Your Universe Online

Eating spicy Indian food could help boost the brains ability to heal itself, according to new research published in Fridays edition of the journal Stem Cell Research and Therapy.

According to Damian Gayle of The Daily Mail, aromatic turmerone, a compound found in the popular curry spice turmeric, could encourage the growth of nerve cells believed to help repair the brains of those suffering from neurodegenerative conditions such as dementia or Alzheimers disease.

In lab tests involving rats, researchers from the Institute of Neuroscience and Medicine (INM-3) in Germany, the University Hospital of Cologne Department of Neurology and the Max Planck Institute for Neurological Research found that aromatic turmerone promoted the proliferation of brain stem cells and their development into neurons.

The study authors believe it could help scientists develop new ways to treat conditions that kill brain cells, which include strokes and Alzheimers. However, they told BBC News health reporter Smitha Mundasad that additional trials are required to see if the affect is applicable to humans.

The researchers injected the rodents with the compound, and then scanned their brains, Mundasad explained. They found that activity increased in the regions of the brain known to be involved in nerve cell growth following infusion with the bioactive compound. Specifically, they found that the subventricular zone (SVZ) was wider and the hippocampus had expanded in the brains of rats injected with aromatic turmerone.

In a different part of the trial, the researchers bathed rodent neural stem cells (NSCs) in different concentrations of aromatic tumerone extract. NSCs are stem cells found within adult brains that differentiate into neurons, and play a vital role in the self-repair and recovery of brain function in neurodegenerative diseases, the authors explained.

Rat fetal NSCs were cultured and grown in six different concentrations of aromatic tumerone during a 72-hour period, and at some concentrations, the compound was shown to increase stem cell proliferation by as much as 80 percent without having any impact on cell death. Furthermore, the cell differentiation process also became accelerated in cells treated with the aromatic tumerone compound when compared to untreated controls.

In a statement, lead author and INM-3 researcher Dr. Maria Adele Rueger said, While several substances have been described to promote stem cell proliferation in the brain, fewer drugs additionally promote the differentiation of stem cells into neurons, which constitutes a major goal in regenerative medicine. Our findings on aromatic turmerone take us one step closer to achieving this goal.

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Common Curry Ingredient Could Help The Brain Battle The Affects Of Alzheimers

How stem cells help cure diseases

MANILA -- The use of stem cell therapy has become an option in treating different medical conditions.

Stem cells are the body's natural healing cells. They are used by human tissues to repair and regenerate damaged cells. In the right environment, stem cells can change into bone, cartilage, muscle, fat, collagen, neural tissue, blood vessels, and even some organs.

There are two kinds of stem cells: adult or embryonic. Adult stem cells appear to be particularly effective against painful joints, repairing cartilage and ligaments, and even painful conditions along the spine.

Adult stem cells are usually harvested from fat tissues. By using technology, the collagen that binds the fat and the stem cells are broken down, separating a solution rich in the patient's own stem cells, which will then be used for treatment.

Stem cells may be effective in the treatment of macular degeneration, Crohns disease and numerous pulmonary conditions such as chronic obstructive pulmonary disease (COPD), asthma, and fibrosis. Stem cells are also being used for patients suffering from kidney failure and ailments of the bone, cartilage and joints.

However, stem cell therapy is not recommended for patients with active infections or cancer.

In the Philippines, fat-derived stem cell therapy is available through StemCare Institute. At present, the clinic employs an orthopedic team of doctors and surgeons with international qualifications.

StemCare, with the advancement of stem cell technology and the refinement its of clinical protocols through international experts, now offers more accessible treatment options for patients suffering from these degenerative orthopedic conditions.

Kim Atienza and Inno Sotto. Composite Image

Among the personalities who have used stem cell therapy in the country are Inno Sotto, a fashion designer who is suffering from a tear in his right elbow, and Kim Atineza, who is using fat stem cell injections to help strengthen and repair his knee joints after suffering from Guillain-Barre disease.

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How stem cells help cure diseases

Stem cell therapies making slow but promising progress

Edgar Irastorza was just 31 when his heart stopped beating in October 2008.

A Miami property manager, break-dancer and former high school wrestler, Irastorza had recently gained weight as his wifes third pregnancy progressed. I kind of got pregnant, too, he said.

During a workout one day, he felt short of breath and insisted that friends rush him to the hospital. Minutes later, his pulse flat-lined.

He survived the heart attack, but the scar tissue that resulted cut his hearts pumping ability by a third. He couldnt pick up his children. He couldnt dance. He fell asleep every night wondering if he would wake up in the morning.

Desperation motivated Irastorza to volunteer for a highly unusual medical research trial: getting stem cells injected directly into his heart.

I just trusted my doctors and the science behind it, and said, This is my only chance, he said recently.

Over the last five years, by studying stem cells in lab dishes, test animals and intrepid patients like Irastorza, researchers have brought the vague, grandiose promises of stem cell therapies closer to reality.

Stem cells broke into the public consciousness in the early 1990s, alluring for their potential to help the body beat back diseases of degeneration like Alzheimers, and to grow new parts to treat conditions like spinal cord injuries.

Progress has been slow. The Michael J. Fox Foundation for Parkinsons Research, an early supporter of stem cell research, pulled its financial backing two years ago, saying that it preferred to invest in research that was closer to providing immediate help for Parkinsons disease patients.

But researchers have been slowly learning how to best use stem cells, what types to use and how to deliver them to the body findings that arent singularly transformational, but progressive and pragmatic.

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Stem cell therapies making slow but promising progress

Stem cell storage deal aims to boost donation levels

Expectant parents will have the option of donating the stem cells to the Governments public bank, or storing them with Precious Cells private bank, at a charge, for their own use.

The deal is the first of its kind for the NHS, and 15 more trusts are holding firm talks with Precious Cells, the company said. The partnership could significantly increase the number of stem cells available for transplants and scientific research in the UK.

Currently, the levels of cord blood donations in Britain are a fraction of those in the US and Australia, and lower than in most European countries.

The company is aiming to broaden its reach to 90 NHS trusts, adding that such widespread partnerships could generate a 180m windfall for the health service.

Dr Husein K. Salem, chief executive of Precious Cells, said the initiative aimed to tackle the UKs laggard position in terms of investment in cord blood stem cell collection and banking.

Stem cell treatment has become increasingly common and is now used for diseases ranging from diabetes to Parkinsons. It is estimated that one in five people will use the regenerative cells to treat a condition or for diagnostics.

The global stem cell market was worth nearly 2.5bn in 2012 and is expected to grow to 3.87bn by 2016.

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Stem cell storage deal aims to boost donation levels