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FDAs Adult Stem Cell Research

By adminMay 6, 2014Stem Cell Medical Center

Scientists who are part of the Food and Drug Administrations MSC Consortium, are studying adult mesenchymal stem cells (MSCs) that could eventually be used to repair, replace, restore or regenerate cells in the body, including those needed for heart and bone repair.

According to the FDA, theinvestigational work is unprecedented: Seven labs at FDA's Center for Biologics Evaluation and Research formed the consortium to fill in gaps in knowledge about how stem cells function.

A consumer update from FDA quotes Carolyn A. Wilson, Ph.D., associate director for research at the center, as saying, This research aims to facilitate development of this important class of innovative medical products. Its the first time weve done anything like this, and its proven to be a very useful approach. Its worked so well because this is a huge, complicated project that requires expertise in many different technologies and methods.

The research could ultimately be key to the advancement of personalized medicine, the practice in which medical treatment is tailored to the needs of an individual patient.Its not science fiction,says Steven R. Bauer, Ph.D., chief of the Cellular and Tissue Therapy Branch in FDAs Office of Cellular Tissue and Gene Therapies.For me, regenerative medicine is the most exciting part of what we regulate in our office.

Visit FDAs Consumer Updates page for more information on adult sem cells and regenerative medicine.

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FDAs Adult Stem Cell Research

Health Beat: Growing stem cells in space: Medicine's next big thing?

By adminMay 6, 2014Stem Cell Clinic

JACKSONVILLE, Fla. -

Hemorrhagic stroke is responsible for more than 30 percent of all stroke deaths. It happens when a weakened blood vessel ruptures and bleeds into the brain.

Its something Jon Galvan experienced five years ago when he almost died from a hemorrhagic stroke while at work.

"I was typing away and I felt a pop in my head," Galvan said.

He was able to recover, but Dr. Abba Zubair, medical director of transfusion medicine and stem cell therapy at Mayo Clinic, Florida, said not everyone is as fortunate.

"If it happens, you either recover completely or die," Zubair said. "Thats what killed my mother."

Zubair said he wants to send bone marrow derived stem cells to the international space station.

"Based on our experience with bone marrow transplant, you need about 200 to 500 million cells," Zubair said.

But conventionally grown stem cells take a month. Experiments on earth have shown that stem cells will grow faster in less gravity.

"Five to ten times faster, but it could be more," Zubair said.

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Health Beat: Growing stem cells in space: Medicine's next big thing?

The New Cellular Medicine from MetroMD Stem Cell PRP Helps Tennis Elbow Sufferers, and Other Athletes to Recover …

By adminMay 6, 2014Uncategorized

Los Angeles, CA (PRWEB) May 05, 2014

Tennis elbow is a common condition affecting 40-60 years aged adults. Though it is not a critical condition, it is potentially disabling in the sense that it restricts the certain activities of tennis players. MetroMD Institute of Regenerative Medicine, Los Angeles, offers an innovative treatment with PRP- Platelet Rich Plasma- a minimally invasive procedure. The therapy takes fewer months for rehabilitation and correct elbow injury in a way that traditional methods cannot do. Source: Dr. Alex Martin - MetroMD Institute of Regenerative Medicine, 7080 Hollywood Blvd, Los Angeles, California.

Tennis elbow is caused by repetitive strain to the tendon in the elbow. Consequently, due to the overuse and strain, elbows have damaged ligaments in the area. Scientifically, this condition is known as lateral epicondylitis. MetroMD, LA, treats vastitude of players with tennis elbow with a minimally invasive procedure with less time for rehabilitation. Dr. Alex Martin, Medical Doctor at the Institute, introduces the latest technologies in regenerative medicine - prolotherapy and platelet-rich plasma treatment (PRP) is one of them. The therapy involves the use of stem cells harvested from the patients bone marrow along with PRP and re-injecting the derived concentrated solution to the damaged soft tissue in the elbow for regeneration. Further, the stem cell specialist accurately places the cells to the troubled area. Once the cells are placed as the way they are required to, the healing process commences. Gradually, the sport players start to restore to full recovery. Patients become able to reuse their elbow and come back to normalcy to continue the sports for as long as they want.

The revolutionary stem cell option is a new attempt to cure the tennis elbow in players with PRP injections to better health. The best part of the treatment is it restores to full health without having the need to go for invasive procedure, unlike conventional surgical methods." says Alex Martin, Medical Doctor, MetroMD, Los Angeles. To know more about the regenerative medicine, please visit http://www.metromd.net.

About MetroMD

MetroMD is a Los Angeles based clinical institute and a leading provider of PRP, Stem Cell Therapy and numerous others. The institute treats the patients with latest technology to treat aging, improve sports performance, texture of hair, nail with HGH therapy. All the treatments are FDA approved and hence considered safe. The institute runs licensed Stem Cell Therapy clinic in Los Angeles. __title__ How to Repair Elbow Joints with PRP]

Irvine Stem Cell Treatment Center Upcoming Lecture Tour

By adminMay 6, 2014Stem Cell Treatment

Irvine, California (PRWEB) May 05, 2014

The Irvine Stem Cell Treatment Center, PC, located in Irvine, California, announces a series of free public seminars on the use of stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief.

The tour dates and locations are as follows:

Wednesday, May 7, 2014 @ 3pm Coco's Restaurant 18380 Brookhurst St., Fountain Valley, CA 92708

Thursday, May 8, 2014 @ 3pm Polly's Pies 18132 Imperial Hwy., Yorba Linda, CA 92886

Friday, May 9, 2014 @ 2pm Polly's Pies 23701 Moulton Pkwy., Laguna Woods, CA 92637

At the Irvine Stem Cell Treatment Center, utilizing investigational protocols, adult adipose derived stem cells (ADSCs) can be deployed to improve patients quality of life with a number of degenerative conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (also called stromal vascular fraction (SVF). Adipose tissue is exceptionally abundant in ADSCs. The adipose tissue is obtained from the patient during a 15 minute mini-liposuction performed under local anesthesia in the doctors office. SVF is a protein-rich solution containing mononuclear cell lines (predominantly autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important Growth Factors that facilitate the stem cell process and promote their activity.

ADSCs are the body's natural healing cells - they are recruited by chemical signals emitted by damaged tissues to repair and regenerate the bodys damaged cells. The Irvine Stem Cell Treatment Center only uses autologous stem cells from a person's own fat no embryonic stem cells are used. Our current areas of study include: Heart Failure, Emphysema, COPD, Asthma, Parkinsons Disease, Stroke, Multiple Sclerosis, and orthopedic joint injections. For more information, or if someone thinks they may be a candidate for one of the stem cell protocols offered by Irvine Stem Cell Treatment Center, they may contact Dr. Gionis directly at (949) 679-3889, or see a complete list of the Centers study areas at http://www.StemCellsUSA.net.

About Irvine Stem Cell Treatment Center: The Irvine Stem Cell Treatment Center is an affiliate of the Cell Surgical Network (CSN). We provide care for people suffering from diseases that may be alleviated by access to adult stem cell based regenerative treatment. We utilize a fat transfer surgical technology to isolate and implant the patients own stem cells from a small quantity of fat harvested by a mini-liposuction on the same day. The investigational protocols utilized by the Irvine Stem Cell Treatment Center have been reviewed and approved by an IRB (Institutional Review Board) which is registered with the U.S. Department of Research Health, Office of Human Reseach Protections (OHRP); and the study is registered with Clinicaltrials.gov, a service of the U.S. National Institutes of Health (NIH). For more information contact: Info(at)StemCellsUSA(dot)net or visit our website: http://www.StemCellsUSA.net.

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Irvine Stem Cell Treatment Center Upcoming Lecture Tour

Scoop.it

By adminMay 6, 2014Stell Cell Research

IBOtoolbox Press Release: The Power of our God Given Adult Stem Cells and how Stem Cell Nutrition capsules mobilize millions more bone marrow adult stem cells into blood circulation within minutes of consumption..and helped restore my eyesight.

EJ Morris's insight:

When Laurence Chilcott talks ... I Listen ! Especially when the topic is natural wellness, optimal health, and anti-aging.

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Go see the record breaking numbers.. the stem cell niche markets are exploding, and Stemtech is the global leader in creating and marketing the World's First patented Stem Cell Nutrition Supplements for people and animals.

EJ Morris's insight:

EJ Morris markets stem cell nutrition products and has been a STEMTech Independent Business Partner since 2005.

Witness the global growth of Stem Cell Nutrition into Russia and virtual stem cell nutrition distributors in India here... http://www.adult-stemcells-blog.com/stem-cell-markets.html

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Listing of Comments on Draft NIH Human Stem Cell Guidelines

By adminMay 6, 2014Stell Cell Research

On April 23, 2009, the National Institutes of Health (NIH) published draft stem cell guidelines for public comment in the Federal Register. The purpose of these guidelines are to implement President Barack Obamas Executive Order 13505 Removing Barriers to Responsible Scientific Research Involving Human Stem Cells, which was issued on March 9, 2009.

NIH received 49,015 comments by May 26, 2009, the closing date of the comment period, and have compiled these comments on this website. Any comments received via email or mail after the May 26 deadline are not included on this website. In reviewing the comments, NIH determined that 60 comments were inappropriate (i.e., contained SPAM responses or offensive language), and these comments have been excluded from this website. In addition, to protect the identities and personal information of individuals who submitted comments, NIH has removed personally identifiable information from the comments on this website even though individuals consented that the information provided could be made available for public review and posting.

| Records 46624 - 46723 of 49015 |

Significant strides have been made over the past decade, and the final guidelines issued by NIH must build on this progress so that cures and new therapies can get to patients as quickly as possible. The final guidelines should not create new bureaucratic hurdles that will slow the pace of progress.

No matter how you look at an embryo, it is A HUMAN BEING, and by "using" it to attempt to save another, you are still taking a human life. Taking one life to save another, MAYBE, that is not even been proven, murder is taking place. No one can decide to end a life without paying a price. If the baby was born live, and then "killed", you would put that person up for being charged for murder. Because it is in the safe haven of the mother's womb doesn't take away from the FACT that is is a human being. JUST LIKE YOU.

Please listen to the pleas of many voters who acknowledge that life begins at conception. Also, that our Creator placed that special life for a special purpose. Being martyred is NOT one of those chosen reasons. God will accept that baby into Heaven and you will have to account for taking an innocent life.

Look deep into your conscience and also read the Constitution of the United States. It gives rights to the unborn. Dare you cross those lines and you will have retribution from above.

What would our founding fathers say? They founded our country on Christian Values. Value your conscience. Thank you for reading this email.

We currently use the NIH approved lines WA09, WA01, HES-3, HES-2 in our research developing stem cell therapies for lung disorder such as Cystic Fibrosis.

[2] Most existing U.S. lines have been derived in accordance with the core principles in the ISSCRs guidelines and consistent with the established federal regulatory framework involving IRB oversight and approval. In some instances, additional specialized embryonic stem cell research oversight committees (ESCROs), and other oversight methods in other countries (referred to as SCROs in ISSCR Guidelines), have also provided oversight. Established policy has demonstrated that this self-regulatory structure has provided a sound ethical foundation for stem cell research. In developing the final Guidelines the NIH should consider this well-established framework of independent oversight and give weight to its determinations.

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Listing of Comments on Draft NIH Human Stem Cell Guidelines

What are Stem Cells? | UNMC

By adminMay 5, 2014Stem Cell Medical Center

What are Stem Cells?

Types of Stem Cells

Why are Stem Cells Important?

Can doctors use stem cells to treat patients?

Pros and Cons of Using Stem Cells

What are Stem Cells?

There are several different types of stem cells produced and maintained in our system throughout life. Depending on the circumstances and life cycle stages, these cells have different properties and functions. There are even stem cells that have been created in the laboratory that can help us learn more about how stem cells differentiate and function. A few key things to remember about stem cells before we venture into more detail:

Stem cells are the foundation cells for every organ and tissue in our bodies. The highly specialized cells that make up these tissues originally came from an initial pool of stem cells formed shortly after fertilization. Throughout our lives, we continue to rely on stem cells to replace injured tissues and cells that are lost every day, such as those in our skin, hair, blood and the lining of our gut.

Source ISSCR

Stem Cell History

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What are Stem Cells? | UNMC

Nuclear transfer to reprogram adult patient cells into stem cells demonstrated

By adminMay 5, 2014Stem Cell Medical Center

7 hours ago

The capacity to reprogram adult patient cells into pluripotent, embryonic-like, stem cells by nuclear transfer has been reported as a breakthrough by scientists from the US and the Hebrew University of Jerusalem.

The work, described in the journal Nature, was accomplished by researchers from the New York Stem Cell Foundation Research Institute and Columbia University and by Nissim Benvenisty, the Herbert Cohn professor of Cancer Research and director of the Stem Cell Unit at the Institute of Life Sciences at the Hebrew University of Jerusalem, and his graduate student Ido Sagi. The latter assisted in the characterization of the pluripotent nature of these cells.

Pluripotency means the ability of stem cells to develop into all the cells of our body, including those in the brain, heart, liver and blood. In 2012, the Nobel Prize in Physiology or Medicine was awarded for two discoveries showing that mature (differentiated) cells can be converted into pluripotent, embryonic-like cells, either by forced expression of genetic factors or by transfer of cell nuclei into female eggs, in a process called "reprogramming."

However, the actual ability to reprogram cells from humans by nuclear transfer had only been accomplished until now by using fetal cells for this purpose, until this latest work involving reprogramming of adult patient cells demonstrated by the researchers from the US and the Hebrew University, as described in the new Nature article.

Future research should allow further characterization of these novel, pluripotent cell types and their comparison to other stem cells. "Human pluripotent stem cells generated from adult cells may change the face of medicine," says Prof. Benvenisty, leading to totally new, personalized genetic therapy involving the reprograming of a patient's own cells to achieve cell replacement and healing.

Explore further: Soft substrates may promote the production of induced pluripotent stem cells

More information: "Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells." Mitsutoshi Yamada, et al. Nature (2014) DOI: 10.1038/nature13287. Received 04 February 2014 Accepted 27 March 2014 Published online 28 April 2014

Converting adult cells into stem cells that can develop into other types of specialized cells is one of the most active areas of medical research, holding great promise for the treatment of disease and repair ...

For the first time, US researchers have cloned embryonic stem cells from adult cells, a breakthrough on the path towards helping doctors treat a host of diseases. ...

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Nuclear transfer to reprogram adult patient cells into stem cells demonstrated

Stem Cells Could Be the Answer for Treating Fecal Incontinence After Injury or Disease

By adminMay 5, 2014Stem Cell Clinic

Durham, NC (PRWEB) May 05, 2014

A new study released today in STEM CELLS Translational Medicine demonstrates the regenerative effects of mesenchymal stem cells (MSC) on the anal sphincter. The work could have implications for the 11 percent of the population suffering fecal incontinence due to an injury or disease.

Massarat Zutshi, M.D., and Levilester Salcedo, M.D., led the research team made up of their colleagues at the Cleveland Clinic (Cleveland, Ohio) as well as those from Summa Cardiovascular Institute and Northeast Ohio Medical University (Akron, Ohio).

None of the current therapies for treating fecal incontinence are efficacious in the long-term or without complications related to the surgery or the device, Dr. Zutshi said. However, she added, adipose tissue, muscle and mesenchymal stem cells (MSC) have been shown to improve functioning of the heart and the urinary sphincter in animal models, leading researchers to test their effects in regenerating the anal sphincter, too.

In this most recent study the Zutshi/Salcedo team wanted to see how a single intramuscular (IM) injection of MSCs compared to a series of intravenous (IV) treatments. They used rats that had undergone an excision of 25 percent of their anal sphincter complex. Twenty-four hours after injury, one group received a single IM injection of stem cells directly into their anal sphincters. A second group began a series of six consecutive daily treatments delivered by IV through their tail veins, as did a group of non-injured animals. Another group of injured animals received no stem cells.

Anal pressures were recorded prior to injury, then again at 10 days and five weeks after treatment. Ten days after the IM treatment, resting and peak pressures were significantly increased in the injured groups compared to the control group that received no treatment. At five weeks, the anal pressures of the two groups of injured rats receiving treatments were almost on par with the non-injured group.

Both IM and IV MSC treatment after injury cause increase in anal pressures sustained at five weeks even though fewer cells were injected IM, Dr. Zutshi concluded. The MSC-treated groups showed less scarring than PBS treatment, with the IV infusion group showing the least scarring.

Since MSC delivered IM or IV both resulted in functional recovery, the IM route may be preferable as fewer cells seem to be needed.

This research demonstrates the regenerative effects of mesenchymal stem cells on the injured anal sphincter and, because fewer cells were needed for intramuscular injections, may direct the course of future clinical trials, said Anthony Atala, M.D., editor of STEM CELLS Translational Medicine and director of the Wake Forest Institute for Regenerative Medicine.

The full article, Functional outcome after anal sphincter injury and treatment with mesenchymal stem cells, can be accessed at http://www.stemcellstm.com.

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Stem Cells Could Be the Answer for Treating Fecal Incontinence After Injury or Disease

Valley Foot Surgeons Now Offering Stem Cell Procedures for Achilles Tendonitis and Tears for Pain Relief and Helping …

By adminMay 5, 2014Stem Cell Treatment

Scottsdale, Arizona (PRWEB) May 05, 2014

Top Phoenix and Scottsdale foot and ankle doctors at Valley Foot Surgeons are now offering stem cell procedures for the nonoperative treatment of Achilles tendonitis and tears. The regenerative medicine procedures are typically able to provide exceptional pain relief while allowing patients the ability to avoid surgery. Call (480) 420-3499 for more information and scheduling about the foot and ankle stem cell procedures.

To date, the lead foot and ankle doctor at Valley Foot Surgeons, Dr. Richard Jacoby, has performed close to 100 regenerative medicine procedures. Typically, these are administered for a variety of conditions such as diabetic ulcers, foot and ankle arthritis, plantar fasciitis, and Achilles injuries.

Conditions with the Achilles tendon may include pain due to chronic tendonitis or tears from degeneration. This may occur during a sporting activity, traumatic event, or simply as part of an individual's tendon weakening after taking quinolone antibiotics.

The stem cell procedures are performed as an outpatient, with the injections consisting of amniotic derived stem cells. The material is harvested from consenting donors after scheduled c-section procedures, with no fetal tissue at all being used.

The material is exceptionally rich in stem cells, growth factors, hyaluronic acid, and more. This can dramatically improve pain relief and healing, which is very different from how steroid medications work.

All too often, traditional treatments for Achilles tendonitis and tears fail to provide relief. This may lead to potentially risky surgery, where complications may lead to continued disability.

With the stem cells for Achilles tears and tendonitis, patients go through an outpatient procedure that is low risk and offers the potential for avoiding the risks of surgery while speeding up recovery.

Dr. Jacoby at Valley Foot Surgeons has been a four time Phoenix Top Doc Winner and sees patients out of two offices in the Valley. For the top stem cell treatment for achilles conditions, diabetic wounds, foot and ankle arthritis and more, call (480) 420-3499.

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Valley Foot Surgeons Now Offering Stem Cell Procedures for Achilles Tendonitis and Tears for Pain Relief and Helping ...