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Funds raised for stem cell transplant

By Stem Cell Doctors

THANKS to the generosity of The Star?s readers, Lau Li Chee, 27, who is fighting a relapse of Hodgkin?s lymphoma, has raised more than enough money for a stem cell transplant.

Cheerful and confident even after four chemotherapy sessions recently, the gutsy girl from Kajang will take another jab to make sure her body is clear from cancer cells before undergoing the transplant.

She has donated RM15,000 from the readers? donations to Persatuan Rumah Caring Kajang that takes care of old folks and single parents, in addition to buying two wheelchairs for the welfare centre.

?Every sen counts. Since I have the medical expenses covered, I think I should channel the surplus to the home to help others in need,? she said.

?I am really thankful for the readers and Rumah Caring. The donors do not know me in person but they are so willing to help me, many also sent me words of encouragement.

?They show me that this world is filled with love and hope. I am more positive now and am confident that I will recover soon,? she said, adding that she is making Thank You cards to send to those with return address.

Her story was highlighted in StarMetro on Jan 30 as she desperately needed RM60,000 for the transplant when doctors told her that the cancer cells had spread from her neck to her stomach.

Prior to that, she had had 16 sessions of chemotherapy over two years, exhausting the family?s savings and all that she could claim from her insurance.

She had always been a diligent girl. Before she was diagnosed with the illness, she worked as an administration staff during the day and ran a noodle stall at night. She was also pursuing a business and finance degree part-time at a local university.

Even though she is not working now to concentrate on her treatment, she often visits the home to look after the aged residents there.

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Funds raised for stem cell transplant

First researcher joins The Jackson Lab for Genomic Medicine in Conn.

By Uncategorized

Bar Harbor – Yijun Ruan, Ph.D., an American geneticist who has pioneered new techniques to sequence and map DNA to better understand cancer growth and stem cell properties, will be the first scientist to join the new Jackson Laboratory for Genomic Medicine (JAX Genomic Medicine) in Farmington, Conn.

Ruan is currently associate director and senior group leader at the Genome Institute of Singapore and professor of biochemistry at the National University of Singapore. He is also an investigator with the Encyclopedia of DNA Elements (ENCODE) project, an international consortium of research groups funded by the National Human Genome Research Institute.
Ruan said he was attracted by The Jackson Laboratory’s famously collaborative research environment, and plans to “take a community approach to tackle genomic questions through intensive collaboration.” Through innovating new technologies and studying how the human and mouse genomes are regulated, he said his goal is to translate research findings into personalized medicine. Ruan has also been appointed director of JAX Genomic Sciences, and will be bringing his current research program and team with him to JAX Genomic Medicine.
JAX Genomic Medicine will unite doctors, patients, scientists and industry to find new ways to tailor disease diagnosis, prevention and treatment to each person’s unique genetic makeup, or genome. Ruan and other recruits will begin initial operations this year in leased space while a 173,000-square-foot permanent facility is designed and built. Construction will begin in 2013, and the new facility will open in 2014.
“Yijun’s broad interests in genome biology, coupled with his innovative approach to developing new research techniques, make him an ideal member of the new JAX Genomic Medicine research team,” said Bob Braun, Ph.D., Jackson’s associate director and chair of research.
After earning BS and MS degrees in microbiology from Huazhong Agricultural University in Wuhan, China, Ruan obtained his Ph.D. in plant molecular biology from the University of Maryland, College Park, where he also conducted postgraduate research. Following scientific appointments at Monsanto Co. in St. Louis and Large Scale Biology Corp. in Vacaville, Calif., Ruan was recruited to the Genome Institute of Singapore (GIS) in 2002. Edison Liu, M.D., former director of GIS and now president and CEO of The Jackson Laboratory, credits Ruan for building the institute’s state-of-the-art genomic technology platforms and its award-winning genome biology programs.
Ruan is an author of 70 research papers and holds patents in Japan, Singapore and the United Kingdom for the DNA analysis techniques he helped to develop. A U.S. citizen, Ruan is married and has two children.
In addition to recruiting research faculty, JAX Genomic Medicine is currently hiring a site director, science coordinator, senior human resources manager, facilities manager and senior financial analyst in Connecticut. Job announcements are on The Jackson Laboratory’s website at http://www.jax.org/careers/connecticut.html.
Braun notes that The Jackson Laboratory is expanding the research faculty at its headquarters campus in Bar Harbor, Maine, as well as recruiting faculty in Connecticut.
The Jackson Laboratory is an independent, nonprofit biomedical research institution and National Cancer Institute-designated Cancer Center based in Bar Harbor, Maine, with a facility in Sacramento, Calif., afuture institute in Farmington, Conn., and a total staff of about 1,400. Its mission is to discover the genetic basis for preventing, treating and curing human disease, and to enable research and education for the global biomedical community.

For more health news, pick up a copy of the Mount Desert Islander.

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First researcher joins The Jackson Lab for Genomic Medicine in Conn.

Susan Samueli, PhD of the Susan Samueli Center for Integrative Medicine UC Irvine to Headline A2Z Health Expo in Los …

By Uncategorized

LOS ANGELES, CA--(Marketwire -02/24/12)- A2Z Health Expo today announced it will hold its 5th annual Health Expo at the Skirball Cultural Center in Los Angeles, CA on Thursday, March 22, 2012 from 4pm to 10pm. According to Dr. Ben Drillings, Director, the keynote speaker for the event will be the co-founder of the Samueli Foundation, Susan Samueli, PhD. Mrs. Samueli serves on the Board and Advisory Board of the Susan Samueli Center for Integrated Medicine (SSCIM) at UC Irvine. SSCIM promotes integrative medicine by providing education, scientific research and a model of clinical care that emphasizes healing of the whole person. Mrs. Samueli was honored with the UCI Medal in March 2000, the 2002 Ellen Cooperman Angel Award Recipient from the John Wayne Cancer Institute and the 2005 General William Lyon Crystal Vision Philanthropy Award from the Orangewood Children's Foundation. In 2006, Susan and Henry Samueli became the owners of the NHL franchise the Anaheim Ducks. The topic of Mrs. Samueli at the expo is: "Integrated Clinic in the 21st Century: Innovations, New Models & Challenges."

The A2Z Health Expo event is focusing on bringing together healthcare professionals, philanthropists, academicians, that are interested in learning more about the integrated clinic model. The expo aims to build a network relationship and sharing of ideas within the health community. Attendees include MDs, Chiropractors, Massage Therapists, Nutritionists, Schools & Spa owners, and general public.

Joining Mrs. Samueli are a bevy of prestigious speakers: Kerry Crofton, PhD., the author of the award-winning book, Wireless Radiation Rescue, and co-founder and executive Director of the International Advisory Board Doctors for Safer Schools; Dr. Nathan Newman, innovator of Stem Cell Lift -- cutting edge cosmetic surgery, without cutting;
And Ms. Alexa Zaledonis, who is the current chair of the National Certification Board for Therapeutic Massage & Bodywork as well as the owner of Even Keel Wellness Spa.

Dr. Drillings is urging the healthcare community to come and learn about the integrated clinic model. This is a must see expo!

The Skirball Cultural Center is located at 2701 N. Sepulveda Blvd., Los Angeles, CA 90049. To register to the event, please visit http://www.a2zhealthexpo.com or email us at expo@a2zhealthexpo.com or call (818) 700-0286.

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Susan Samueli, PhD of the Susan Samueli Center for Integrative Medicine UC Irvine to Headline A2Z Health Expo in Los ...

BrainStorm Featured on CNBC

By Stem Cell Medical Center

NEW YORK & PETACH TIKVAH, Israel--(BUSINESS WIRE)--

BrainStorm Cell Therapeutics Inc. (OTCBB: BCLI.OB - News), a developer of innovative stem cell technologies for neurodegenerative disorders, announced that NurOwn™, its autologous stem cell therapy for amyotrophic lateral sclerosis (ALS), or Lou Gehrig's Disease, was profiled yesterday on CNBC. In the Feature Story about the impact of Iran's nuclear threat, Israeli business and scientific leaders were interviewed about Israel's thriving economy and cutting edge technologies. Among those leaders that met with CNBC were Brainstorm’s President Mr. Chaim Lebovits and Prof. Dimitrios Karussis, Principal Investigator of Brainstorm's Phase I/II clinical trial currently underway at the Hadassah Medical Center in Jerusalem.

Brainstorm recently announced positive initial results from the clinical trial, resulting in approval from Hadassah's Helsinki committee to proceed with the trial. Accordingly, additional patients have been enrolled in the study, and Brainstorm will announce additional results in the coming months.

To see the video online, follow the link at: http://video.cnbc.com/gallery/?video=3000074883

To read the Feature Story online, follow the link at: http://www.cnbc.com/id/46484576

Safe Harbor Statement
Statements in this announcement other than historical data and information constitute "forward-looking statements" and involve risks and uncertainties that could cause BrainStorm Cell Therapeutics Inc.'s actual results to differ materially from those stated or implied by such forward-looking statements. The potential risks and uncertainties include risks associated with BrainStorm's limited operating history, history of losses; minimal working capital, dependence on its license to Ramot's technology; ability to adequately protect the technology; dependence on key executives and on its scientific consultants; ability to obtain required regulatory approvals; and other factors detailed in BrainStorm's annual report on Form 10-K and quarterly reports on Form 10-Q available at http://www.sec.gov. The Company does not undertake any obligation to update forward-looking statements made by us.

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BrainStorm Featured on CNBC

Maven Semantic: Embryonic Stem Cells Research Database

By Stem Cell Medical Center

DUBLIN--(BUSINESS WIRE)--

Maven Semantic (http://www.mavensemantic.com) announces updates to their Embryonic Stem Cells research database.

The new database is now available to marketing, business development, competitor intelligence, KOL, medical affairs and related departments in the life sciences sector.

The database currently tags 27,000 individuals working in Embryonic Stem Cells. http://bit.ly/zc0cU4.

Top 10 Countries for Embryonic Stem Cells Research (ranked by number of senior researchers)

Leading organisations in Embryonic Stem Cells research include:

Albert Einstein College of Medicine Baylor College of Medicine Brigham and Women's Hospital California Institute of Technology Chinese Academy of Sciences Cornell University Dana-Farber Cancer Institute Duke University Medical Center Fred Hutchinson Cancer Research Center Genome Institute of Singapore Harvard Medical School Howard Hughes Medical Institute Hubrecht Laboratory Indiana University School of Medicine Institut Pasteur Institute for Frontier Medical Sciences Institute of Human Genetics Institute of Molecular Embryology and Genetics Johns Hopkins University School of Medicine Karolinska Institute Keio University School of Medicine Lund University Mount Sinai Hospital New York University School of Medicine Seoul National University University College London University of Cambridge University of Chicago University of Massachusetts Medical School University of Michigan University of Pennsylvania University of Toronto University of Tsukuba Weill Medical College of Cornell University Zhejiang University

The database also includes pharmaceutical companies, biotech companies, CROs, hospitals, government labs and other organisations active in the Embryonic Stem Cells research field.

Sample companies in database include:

AgResearch Ltd Amgen Inc Axiogenesis AG Cellartis AB Cellular Dynamics International, Inc Chugai Pharmaceutical Co., Ltd DNAVEC Corporation ES Cell International Pte Ltd F. Hoffmann-La Roche Ltd Genentech, Inc GENPHARM INTERNATIONAL, INC Geron Corporation Hayashibara Biochemical Laboratories, Inc Illumina, Inc Ingenium Pharmaceuticals AG Invitrogen Corporation Japan Science and Technology Corp KENNEDY KRIEGER, INC Regeneron Pharmaceuticals, Inc

What is Maven:

- Largest database of international medical professionals, with over 6,000,000 people and over 500,000 medical organisations;

- All records are downloadable to excel or in-house database, with email, postal address and phone contacts;

- Profile and segment the entire database using over 47,000 diseases and therapeutic areas

For more information visit http://www.mavensemantic.com/

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Maven Semantic: Embryonic Stem Cells Research Database

Virginia G. Piper Cancer Center Opens Cancer Transplant Institute

By Stem Cell Treatment

To: HEALTH, MEDICAL AND STATE EDITORS

New hematopoietic stem cell transplant program in Scottsdale, Ariz. offers treatment for blood cancers

SCOTTSDALE, Ariz., Feb. 24, 2012 /PRNewswire-USNewswire/ -- The Virginia G. Piper Cancer Center at Scottsdale Healthcare announced today it has added a hematopoietic stem cell (HSC) transplant cancer treatment program (a/k/a bone marrow transplant) through its new Cancer Transplant Institute.

Leaders of the new cancer treatment program expect it to attract transplant patients from greater Phoenix, across Arizona and the southwestern United States. HSC transplants are primarily used to treat patients with aggressive cancers such as myelomas, leukemias and lymphomas.

The Cancer Transplant Institute at the Virginia G. Piper Cancer Center is located on the campus of Scottsdale Healthcare Shea Medical Center, and includes an outpatient treatment unit and a 13-bed inpatient unit.

Cancer patients needing HSC transplants receive very high doses of chemotherapy designed to kill aggressive tumors. In the process their own bone marrow is damaged, resulting in low blood counts and weakened immune systems. Stem cells that are collected prior to therapy are then given to "rescue" the patient from the effects of the high dose therapy. Stem cells can be collected from the patients themselves (autologous) or a donor (allogeneic). Although often referred to as a bone marrow transplant, more commonly the stem cells are now collected from the blood stream.

"In these aggressive disorders regular chemotherapy isn't enough to kill the tumor cells," explains bone marrow transplant specialist Jeffrey Schriber, MD, medical director of the Virginia G. Piper Cancer Center Cancer Transplant Institute. "Unfortunately, the high dose therapy is so intense that without the stem cell rescue, patients would not survive due to the lack of white cells which prevent infection and platelets that prevent bleeding. This therapy allows us to safely give the chemotherapy necessary to cure these aggressive cancers."

A critical component to success is working closely with the patient's primary oncologist to develop an appropriate plan for them, said Schriber. "We are thrilled that despite just opening our doors we have already seen over 50 patients and performed our first transplant," he noted.

The Cancer Transplant Institute at the Virginia G. Piper Cancer Center is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) for autologous and allogeneic adult transplants. The Institute also is a member of the National Marrow Transplant Program (NMDP), which enables it to perform unrelated donor transplants.

"The Cancer Transplant Institute brings an invaluable service to the Virginia G. Piper Cancer Center and the community, and we are honored to have this program here at Scottsdale Healthcare," said Lindsay Thomas, RN, MSN, OCN, CNAA, director of oncology services.

The Virginia G. Piper Cancer Center at Scottsdale Healthcare is located 10460 N. 92nd St., Scottsdale, Ariz. 85260 on the campus of Scottsdale Healthcare Shea Medical Center. For more information, contact the Cancer Care Coordinator at 480-323-1255 (toll free: 1-877-273-3639) or email ccc@shc.org.

SOURCE Scottsdale Healthcare

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Virginia G. Piper Cancer Center Opens Cancer Transplant Institute

Memory formation triggered by stem cell development

By Stem Cell Medical Center

Public release date: 23-Feb-2012
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Contact: RIKEN Brain Science Promotion Division
pr@brain.riken.jp
81-484-679-757
RIKEN

Researchers at the RIKEN-MIT Center for Neural Circuit Genetics have discovered an answer to the long-standing mystery of how brain cells can both remember new memories while also maintaining older ones.

They found that specific neurons in a brain region called the dentate gyrus serve distinct roles in memory formation depending on whether the neural stem cells that produced them were of old versus young age.

The study will appear in the March 30 issue of Cell and links the cellular basis of memory formation to the birth of new neurons -- a finding that could unlock a new class of drug targets to treat memory disorders.

The findings also suggest that an imbalance between young and old neurons in the brain could disrupt normal memory formation during post-traumatic stress disorder (PTSD) and aging. "In animals, traumatic experiences and aging often lead to decline of the birth of new neurons in the dentate gyrus. In humans, recent studies found dentate gyrus dysfunction and related memory impairments during normal aging," said the study's senior author Susumu Tonegawa, 1987 Nobel Laureate and Director of the RIKEN-MIT Center.

Other authors include Toshiaki Nakashiba and researchers from the RIKEN-MIT Center and Picower Institute at MIT; the laboratory of Michael S. Fanselow at the University of California at Los Angeles; and the laboratory of Chris J. McBain at the National Institute of Child Health and Human Development.

In the study, the authors tested mice in two types of memory processes. Pattern separation is the process by which the brain distinguishes differences between similar events, like remembering two Madeleine cookies with different tastes. In contrast, pattern completion is used to recall detailed content of memories based on limited clues, like recalling who one was with when remembering the taste of the Madeleine cookies.

Pattern separation forms distinct new memories based on differences between experiences; pattern completion retrieves memories by detecting similarities. Individuals with brain injury or trauma may be unable to recall people they see every day. Others with PTSD are unable to forget terrible events. "Impaired pattern separation due to the loss of young neurons may shift the balance in favor of pattern completion, which may underlie recurrent traumatic memory recall observed in PTSD patients," Tonegawa said.

Neuroscientists have long thought these two opposing and potentially competing processes occur in different neural circuits. The dentate gyrus, a structure with remarkable plasticity within the nervous system and its role in conditions from depression to epilepsy to traumatic brain injury -- was thought to be engaged in pattern separation and the CA3 region in pattern completion. Instead, the MIT researchers found that dentate gyrus neurons may perform pattern separation or completion depending on the age of their cells.

The MIT researchers assessed pattern separation in mice who learned to distinguish between two similar but distinct chambers: one safe and the other associated with an unpleasant foot shock. To test their pattern completion abilities, the mice were given limited cues to escape a maze they had previously learned to negotiate. Normal mice were compared with mice lacking either young neurons or old neurons. The mice exhibited defects in pattern completion or separation depending on which set of neurons was removed.

"By studying mice genetically modified to block neuronal communication from old neurons -- or by wiping out their adult-born young neurons -- we found that old neurons were dispensable for pattern separation, whereas young neurons were required for it," co-author Toshiaki Nakashiba said. "Our data also demonstrated that mice devoid of old neurons were defective in pattern completion, suggesting that the balance between pattern separation and completion may be altered as a result of loss of old neurons."

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The work was supported by the RIKEN-MIT Center for Neural Circuit Genetics, Howard Hughes Medical Institute, Otsuka Maryland Research Institute, Picower Foundation and the National Institutes of Health.

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Memory formation triggered by stem cell development

ISSCR Honors Stem Cell Research Pioneer with Prestigious McEwen Award for Innovation

By Stem Cell Treatment

Newswise — The International Society for Stem Cell Research (ISSCR) is pleased to announce the winner of the 2012 McEwen Award for Innovation, a coveted prize in the field of stem cell research and regenerative medicine. The 2012 recipient is Rudolf Jaenisch, MD, Founding Member of the Whitehead Institute for Biomedical Research and Professor of Biology at the Massachusetts Institute of Technology in recognition of his pioneering discoveries in the areas of genetic and epigenetic control of development in mice that directly impact the future potential of embryonic stem cells and induced pluripotent stem cells for therapeutic utility.

The McEwen Award for Innovation is supported by the McEwen Centre for Regenerative Medicine in Toronto, Ontario, Canada. The $100,000 award honors original thinking and groundbreaking research pertaining to stem cells or regenerative medicine that opens new avenues of exploration towards the understanding or treatment of human disease or affliction.

“Rudolf Jaenisch has consistently contributed new and groundbreaking discoveries to stem cell biology and regenerative medicines that have changed the way stem cell research is conducted, said Fred H. Gage, PhD, ISSCR President. “Importantly, Rudolf not only has an uncanny sense of the next big question, but also conducts his experiments with such thoughtful and critical experimental design that his results have an immediate impact. This critical attention to detail and experimental design has greatly benefited the many gifted students that have passed through his lab and now populate many of the major stem cell centers throughout the world. Rudolf is very deserving of this award.”

Winner of the inaugural McEwen Award for Innovation in 2011, Shinya Yamanaka, MD, PhD, ISSCR President-Elect agrees. “Dr. Rudolf Jaenisch has always been on the cutting-edge of our field and his research has been a source of inspiration not only for myself, but has influenced the careers of some of our most esteemed colleagues.”

Dr. Jaenisch will be presented with the award at the ISSCR 10th Annual Meeting, in Yokohama, Japan, on Wednesday, June 13, 2012.
***
The International Society for Stem Cell Research is an independent, nonprofit membership organization established to promote and foster the exchange and dissemination of information and ideas relating to stem cells, to encourage the general field of research involving stem cells and to promote professional and public education in all areas of stem cell research and application.

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ISSCR Honors Stem Cell Research Pioneer with Prestigious McEwen Award for Innovation

Waisan Poon, "Clinical trial of umbilical cord blood stem cells in spinal cord injury" – Video

By Uncategorized

22-02-2012 05:16 Waisan Poon, Chinese U, Hong Kong, speaking on, "Clinical trial of umbilical cord blood stem cells in spinal cord injury" at the International Conference of Stem Cells and Regenerative Medicine for Neurodegenerative Diseases to be held at the Tzu-Chi Hospital in Hualien, Taiwan on April 22-24, 2010.

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Waisan Poon, "Clinical trial of umbilical cord blood stem cells in spinal cord injury" - Video

Surgeons Urge Caution: Stem Cell Treatments Untested in Aesthetic Surgery

By Stem Cell Treatment

Doctors Haeck, Eaves, and Rohrich write joint ASAPS/ASPS statement calling for more research into stem cell facelift and stem cell breast augmentation.

Dallas, TX (PRWEB) February 22, 2012

There is little evidence to support the safety and effectiveness of procedures, equipment and treatments that have been advertised using adult stem cells for aesthetic reconstruction, including plastic surgery and facial rejuvenation, according to physicians writing in Plastic and Reconstructive Surgery.

Dr. Rod J. Rohrich, chairman of the Department of Plastic Surgery at UT Southwestern Medical Center and editor-in-chief of the journal, published a position statement on “stem cell facelifts” and “stem cell breast augmentation,” also known as “natural breast augmentation.” Dr. Felmont F. Eaves III of Chapel Hill, N.C., and Dr. Phillip C. Haeck of Seattle, Wash.,collaborated on the statement on behalf of the American Society for Aesthetic Plastic Surgery (ASAPS) and the American Society of Plastic Surgeons (ASPS).

“There are encouraging data from studies in laboratories to suggest that the use of adult stem cells is a very promising field and may produce beneficial medical therapies to treat a variety of diseases,” the doctors said in the statement. They emphasized that there is a lack of consistency in the way stem cell facelift procedures are performed, and pointed out that many procedures are being advertised by physicians who are not board-certified for this type of treatment, and devices being sold for aesthetic stem cell treatments have not been approved for human use in the U.S.

In the report, the doctors encourage their peers to continue reporting clinic results and experimental research to peer-reviewed plastic surgery journals to both promote good science and to foster safety and best practices for stem cell use in aesthetic procedures. “Much more research needs to be conducted before any definitive statements can be made,” the report said. “[Until then,] stem cell based procedures should be performed in compliance with FDA regulatory guidelines.”

Dr. Rohrich said many of the advertisements claiming stem cells can aid in restoring facial and body youthfulness come from outside the U.S. “Further direct, approved clinical research is needed to validate those claims,” he said, “but the future is potentially bright for the use of adult stem cells in both plastic surgery and facial rejuvenation, as well as in medical procedures, such as restoring nerve and brain damage resulting from trauma or cancer, as well as reversing the severe effects of auto immune disease.”

To read the complete joint ASAPS/ASPS position statement on stem cell use in aesthetic surgery, including stem cell facelifts and natural breast augmentation, visit the ASPS, at their website.

About Rod J. Rohrich, M.D., F.A.C.S.

Dr. Rod J. Rohrich holds the Betty and Warren Woodward Chair in Plastic and Reconstructive Surgery at UT Southwestern Medical Center in Dallas, Texas. He also holds the UT Southwestern Medical Center Crystal Charity Ball Distinguished Chair in Plastic Surgery. He is a graduate of the Baylor College of Medicine with high honors, with residencies at the University of Michigan Medical Center and fellowships at the Massachusetts General Hospital/Harvard (hand/microsurgery) and Oxford University (pediatric plastic surgery). He has served as president of the American Society of Plastic Surgeons. He repeatedly has been selected by his peers as one of America's best doctors, and twice has received one of his profession's highest honors, the Plastic Surgery Educational Foundation Distinguished Service Award, which recognizes his contributions to education in his field. Dr. Rohrich participates in and has led numerous associations and councils for the advancement of plastic and reconstructive surgery. He is a native of North Dakota. He is married to Dr. Diane Gibby, also a plastic surgeon. They live in Texas with their two children.

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Rod J. Rohrich, M.D.
Rod J. Rohrich M.D.
(214) 821-9114
Email Information

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Surgeons Urge Caution: Stem Cell Treatments Untested in Aesthetic Surgery

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