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Global Cell Separation Technology Market Remarkable Growth Factors, New Innovations and Forecast Till 2028- Zi – openPR

Global Point Of Care Diagnostics Market

Major parameters covered under these company profiles include revenues, gross profits, operating income, COGS, EBITDA, sales volume, product offerings, company landscape analysis, key strategic moves, key recent developments, and technological roadmap. We provides a complete understanding of general market scenarios and future market situations to prepare for rising above the challenges and ensuring strong growth, the complete analysis of Cell Separation Technology Market Size, Data and development forecast from 2022-2028.

Also, representing the Cell Separation Technology Market Factor Analysis- Porter's Five Forces, Supply/Value Chain, PESTEL analysis, CAGR value, product offerings, company landscape analysis, Market Entropy, CAPEX cycle, COGS Analysis, EBITDA analysis, Patent/Trademark Analysis, and Post COVID Impact Analysis. Key Leading Players having extreme Growth Rate in last Few decades included Carl Zeiss AG, Lumenis Ltd, FEI Company, Hamamatsu Photonics K.K, Becton, Dickinson and Company, Perkinelmer, Andor Technology Ltd, Affymetrix Inc, Olympus Corporation of the Americas.

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Don't miss out on the Analysis of business opportunities in the Cell Separation Technology Market. Speak to our analysts and gain vital industry insights that will help you for your business growth.

The Major Manufactures covered in this Report:- Carl Zeiss AG, Lumenis Ltd, FEI Company, Hamamatsu Photonics K.K, Becton, Dickinson and Company, Perkinelmer, Andor Technology Ltd, Affymetrix Inc, Olympus Corporation of the Americas.

Global Cell Separation Technology Market Product and Application Are:-

Product: Immunomagnetic Cell Separation, Fluorescence-Activated Cell Sorting, Density Gradient Centrifugation, Microfluidic Cell Separation, And Others

Application: Stem Cell Research, Immunology, Neuroscience, Cancer Research, And Others

Our analysts covers all key parameters required for COVID-19 effect on business industry, economic implications their trends, factors, consumer behavior on shopping, effect on spending lot of money on advertising and also on useful industries like medical, transportation, food and Beverage. The globally rising of Bio crisis 'COVID-19' has many businesses are struggling and confused on what steps to take to minimize or maximize the economic impact.

The Global Cell Separation Technology Market Research Report Forecast 2022-2028 is a valuable source of insightful data for business strategists. It provides the Cell Separation Technology industry overview with growth analysis, historical & futuristic cost, revenue, demand and supply data. The research analysts provide an elaborate description of the value chain and its distributor analysis. This Cell Separation Technology market study provides comprehensive data which enhances the understanding scope and application of this report.

Geographically, Global Cell Separation Technology Market covers:- United States, Europe, China, Japan, India and Southeast Asia and rest of the world

(Our Analyst can add Regional analysis as per your Research need also)

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Timeline for Analysis:-

History Year: 2016- 2020 Base Year: 2021 Forecast Year: 2022 to 2028

Key Stakeholders

Cell Separation Technology Manufacturers Cell Separation Technology Distributors/Traders/Wholesalers Cell Separation Technology Subcomponent Manufacturers Industry Association Downstream Vendors

Key questions answered in this report

What are the key market trends? What is driving this market? What are the challenges to market growth? Who are the key vendors in this market space? What are the market opportunities and threats faced by the key vendors? What are the strengths and weaknesses of the key vendors?

The study objectives of this report are:-

To analyze the opportunities in the market for stakeholders by identifying the high growth segments. To strategically analyze each submarket with respect to individual growth trend and their contribution to the market To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market. To analyze and study the Cell Separation Technology capacity, production, value, consumption and forecast (2022-2028) Focuses on the global key manufacturers to describe and analyze the market competition landscape with SWOT analysis. To define, describe and forecast the market by type, application and region. To analyze the global key regions market potential and advantages, opportunities, challenges, restraints and risks. To identify significant trends and factors driving or inhibiting the market growth. To strategically profile the key players and comprehensively analyze their growth strategies.

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Global Point Of Care Diagnostics Market Key Drivers, Size & Share 2022-2028 Report by Zion Market Research: https://www.openpr.com/news/2757927/global-point-of-care-diagnostics-market-key-drivers-size-share

Global Personal Care Appliances Market: https://www.einnews.com/pr_news/593358124/global-personal-care-appliances-market-growth-increasing-more-than-usd-29-25-billion-by-2028-says-zion-market-research

Global Space Situational Awareness (SSA) Market: https://www.einnews.com/pr_news/593198972/at-cagr-4-6-global-space-situational-awareness-ssa-market-expected-to-reach-approximately-usd-1-495-million-by-2027

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Global Cell Separation Technology Market Remarkable Growth Factors, New Innovations and Forecast Till 2028- Zi - openPR

Nancy and Geoffrey Stack Family Foundation give $2 million to UCI Health – UCI News

Oct. 3, 2022, Irvine, Calif. UCI Health is pleased to announce a $2 million gift that will benefit the emergency department in the new $1.3 billion UCI Health Irvine medical campus being built on the corner of Jamboree Road and Birch Street in Irvine.

The gift, funded by the Nancy and Geoffrey Stack Family Foundation, will name the patient welcome areas in the emergency department of the planned acute care hospital and at the Chao Family Comprehensive Cancer Care and Ambulatory Care building.

UCI Health is grateful for the friendship and generosity of Nancy and Geoffrey Stack, said UCI Health CEO Chad Lefteris. With their support, we continue to improve access to the clinical innovation, lifesaving research, and world class care of Orange Countys only academic health system.

In November, UCI and the universitys health enterprise, UCI Health, officially broke ground on the medical complex, which will include a 144-bed general acute care hospital with an emergency department, the Chao Family Comprehensive Cancer Center and Ambulatory Care center and the Joe C. Wen & Family Center for Advanced Care.

The UCI Health Irvine complex will support the systems growing primary and specialty care network in coastal and south Orange County, Lefteris said.

UCI Health is a beacon of hope in Orange County, said Nancy Stack. The new medical complex will bring hope and healing to our region and will save lives. Jeff and I are honored to support such a worthwhile cause.

The Stacks are longtime supporters of UCI Health. The couple has made previous philanthropic gifts to support UCI Medical Center in Orange. They have continued their legacy of giving by investing in healthcare through the UCI Health Irvine medical campus.

The new UCI Health Irvine medical campus will complement the UCI Medical Center in Orange and will be a key part to providing the region with the advanced care available only from a health system that is part of a leading, premier academic research institution. The hospital will include a 24-hour emergency department and focus on leading clinical programs including oncology, neurology, neurosurgery, orthopedics, and digestive health. The first patients are expected in 2023 at the Joe. C. Wen & Family Center for Advanced Care. The Chao Family Comprehensive Cancer Care and Ambulatory Care building, and the hospital will begin serving patients in 2023 and 2025, respectively.

Nancy and Geoffrey Stack Family Foundation was created by the longtime Orange County residents to support education, health and other vital community-based programs in Orange County and beyond. Geoffrey Stack is one of the founding partners of the Sares-Regis Group, a commercial and residential real estate development and management firm. Nancy Stack is founder and president of the Cystinosis Research Foundation, which supports medical research including stem cell research seeking a cure for the rare disease cystinosis.

If you want to learn more about supporting this or other activities at UCI, please visit the Brilliant Future website athttps://brilliantfuture.uci.edu. Publicly launched on Oct. 4, 2019, the Brilliant Future campaign aims to raise awareness and support for UCI. By engaging 75,000 alumni and garnering $2 billion in philanthropic investment, UCI seeks to reach new heights of excellence instudent success,health and wellness, research and more. UCI Health plays a vital role in the success of the campaign. Learn more by visiting https://brilliantfuture.uci.edu/uci-health/

About UCI Health:UCI Healthis the clinical enterprise of the University of California, Irvine. Patients can access UCI Health at primary and specialty care offices across Orange County and at its main campus,UCI Medical Center in Orange, Calif. The 459-bed acute-care hospital, listed among Americas Best Hospitals byU.S. News & World Reportfor 22 consecutive years, provides tertiary and quaternary care, ambulatory and specialty medical clinics, as well as behavioral health and rehabilitation services. UCI Medical Center is home to Orange Countys onlyNational Cancer Institute-designated comprehensive cancer center,high-risk perinatal/neonatal programandAmerican College of Surgeons-verified Level I adult and Level II pediatric trauma centerandregional burn center. It is the primary teaching hospital for theUCI School of Medicine. UCI Health serves a region of nearly 4 million people in Orange County, western Riverside County and southeast Los Angeles County. Follow us onFacebookandTwitter.

About the University of California, Irvine:Founded in 1965, UCI is the youngest member of the prestigious Association of American Universities and is ranked among the nations top 10 public universities byU.S. News & World Report. The campus has produced three Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UCI has more than 36,000 students and offers 224 degree programs. Its located in one of the worlds safest and most economically vibrant communities and is Orange Countys second-largest employer, contributing $7 billion annually to the local economy and $8 billion statewide. For more on UCI, visitwww.uci.edu.

Excerpt from:
Nancy and Geoffrey Stack Family Foundation give $2 million to UCI Health - UCI News

Promaxo Announces Six System Sales in the Third Quarter 2022 – The Bakersfield Californian

OAKLAND, Calif., Oct. 04, 2022 (GLOBE NEWSWIRE) -- Promaxo, Inc. (Promaxo or the Company), a medical imaging, robotics, and AI technology company, today announced the sale of six systems in the United States in the third quarter ending September 30, 2022. The system sales included both operating lease and revenue share agreements with physician practices in Florida, New Jersey, and Texas. Promaxos single-sided MRI with AI based imaging system, FDA cleared for in-office use, empowers practices and hospitals to accurately and seamlessly guide prostate interventions under the Promaxo MRI system.

In the third quarter, North Florida Urology Associates in Gainesville, FL, Avant Concierge Urology in Winter Garden, FL, Urology Center of Winter Park in Winter Park, FL, Sovereign Health System in Jersey City, NJ, Jersey Urology Group in Somers Point, NJ, and Urology America MSO in Austin, TX entered into agreements with Promaxo.

Dr. Sijo Parekattil, Director of Avant Concierge Urology and Associate Professor of Urology at the University of Central Florida said, Given our focus on leveraging the latest technologies, robotics and microsurgery in our urology practice, incorporating the Promaxo MRI system into our programs was a natural and synergistic next step. Coupled with the flexibility of commercial partnership programs offered by Promaxo, we are impressed with the ease at which we place the system in our office and with how quickly we begin to provide Promaxo MRI procedures to our patients.

With focused market penetration activities, we are pleased to add six new physician practices to Promaxos growing clinical network in the United States, maintaining our growth momentum through the third quarter 2022, said Dr. Amit Vohra, Founder and CEO of Promaxo. We are committed to making MRIs more accessible for interventions, as we continue to partner with physician offices through our flexible sales and financing programs.

About Sovereign Health System

Sovereign Health System is a multi-specialty community healthcare system, with primary and specialty medical care provided by the physicians of the Sovereign Health Medical Group, in addition to outpatient care provided by Sovereign Health Urgent Care, Sovereign Health Cancer Care, and Sovereign Health SurgiCare. Sovereign Health Medical Group has ten urology practice locations in New Jersey.

About North Florida Urology Associates

North Florida Urology Associates is a medical practice with clinics in Ocala, Gainesville, and The Villages, Florida. With a focus on promoting mens health for over 36 years, the practice has raised awareness and led its field in treating conditions such as prostate cancer, erectile dysfunction, and kidney stones by leveraging leading technologies. The practice utilizes technologies such as HIFU, ErosWave, cryosurgery, shockwave therapy, and stem cell therapy to address and treat their patients needs.

About Avant Concierge Urology

Avant Concierge Urology is a Central Florida urology practice, specializing in the treatment of conditions related to the kidneys, urinary bladder, adrenal glands, urethra, and male reproductive organs. Avant offers personalized, best-in-class surgical treatment options, with the intent to minimize downtime, scarring, and expenses. With focus on offering latest technologies, including digital microsurgery, Avant is the first and only in-office operator of the Karl STORZ 3D Vitom digital microsurgery system in the United States, offering patients a best-in-class surgery solution allowing for better precision and decreased recovery time.

About Jersey Urology Group

Jersey Urology Group is a comprehensive urology practice in southern New Jersey, with a team of top urology doctors in New Jersey offering patients state-of-the-art technologies and innovative therapies for the treatment of all urologic conditions. Urology services include treating kidney stones, prostate problems, infertility, and other complex urological issues.

About Urology Center of Winter Park

Urology Center of Winter Park, centrally located in Florida at Winter Park, utilizes state of the art, minimally invasive urological procedures in the diagnosis and treatment of all types of urological issues. The practice provides medical solutions dedicated to all aspects of urological care with the latest in minimally, and non-invasive techniques to reduce pain and hasten recovery. Services include urology, urologic surgery and urologic oncology.

About Urology America MSO

Urology America is a national, best-in-class urology platform founded in Central Texas by Urology Austin physicians and Gauge Capital. Urology Americas mission is to build a platform that provides unparalleled support to providers and care team, to deliver exceptional and comprehensive urological care, with compassion and service that exceeds expectations. Urology America is built with a focus on achieving returns through innovation and revenue growth. This includes drawing on expertise and collective experience to develop new services where applicable.

About Promaxo, Inc.

Promaxo was founded by a team of entrepreneurs and healthcare innovators to develop a minimally-invasive and patient-centric MRI and robotic platform. Based in Oakland, California, and backed by over 200 patents, the Companys mission is to improve lives through state-of-the-art medical imaging, robotics and AI capabilities. With a compact and adaptable MRI, Promaxo is redefining the standard of care by improving the quality and speed of patient diagnosis and interventions. The Company has formed numerous long-term and strategic partnerships with investor groups and corporation as it drives commercialization of the Promaxo MRI system.

To learn more about the technology behind the MRI system and its scope, please visit: Promaxo.com.

LinkedIn: Promaxo

Twitter: @Promaxo

Facebook: Promaxo

Investors

Gilmartin Group

Vivian Cervantes

e: IR@promaxo.com

Link:
Promaxo Announces Six System Sales in the Third Quarter 2022 - The Bakersfield Californian

Announcement of Training in Fort Lauderdale, Florida by The Global Stem Cells Group – Digital Journal

Recently, the Global Stem Cells Group announced plans to teach physicians the value and process behind incorporating regenerative medicine into their own clinical practices.

MIAMI 4 Octocber, 2022 Global Stem Cells Group, a multidisciplinary community of scientists and physicians that are working together to cure diseases and relieve human pain through the advancement of the field of regenerative medicine, announced today a plan of training in Fort Lauderdale on November 4th and 5th. This training aims to equip physicians with the value and knowledge behind incorporating regenerative medicine into their own clinical practice.Benito Novas, CEO of GSCG,is confident that the event will bring together a group of:

i. Doctors are seeking training, products, and equipment in regenerative medicine.

ii. Doctors who care for patients with conditions that can be treated with cell therapies

iii. Aesthetic doctors.

iv. Doctors who want to be up to date with the latest technologies and protocols

v. Doctors with an interest in new research on stem cells, MSC, Exosomes, and medical networks want to attract more clients.

The training course is intended to cover:

Hands-On portion:Doctors, in a controlled environment and guided by a team of medical professionals, will have the opportunity to see procedures being performed a few feet away and then get the opportunity to try them for themselves.

Review of stem cell biology

Characterization of cells, cell products, cytokines, and growth factors, as well as their capacity for regeneration.

Laboratory Processes

Clinical applications

Product validation

Practice Management

Patient acquisition

TheInternational Society for Stem Cell Application (ISSCA)has done intensive research on this topic and the team will take a lead in educating, training, and certification during the event. As a medical speciality, regenerative standards and certification are very important, which is why ISSCA will provide certificates after the training. By the end of the training course, you will understand everything you need to know to add adult stem cellbased procedures to your existing practice. As before, the united efforts of the seven major medical corporations will provide practitioners with a one-stop hub for stem cell solutions that adhere to the highest medical standards.

To find more about the courses and to make reservations for this particular event, head on to their website http://www.issca.us/autologous-miami-november/ .us email [emailprotected] or dial +1305 560 5337.

AboutISSCA

ISSCA is a multidisciplinary community that brings together scientists and physicians, all of whom aspire to treat diseases and relieve human pain through advances in science, technology, and the practice of regenerative medicine. ISSCA serves its members through innovations made to the speciality of regenerative medicine. The ISSCAs vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, training, research, education, and certification.

As a medical speciality, regenerative medicine standards and certifications are very important, which is why ISSCA provides certification training globally. This is because they want to encourage more physicians to practice regenerative medicine and make it accessible to benefit patients both nationally and worldwide. Incorporated under the Republic of Korea as a nonprofit entity, the ISSCAs main goal is to promote excellence and standards in the field of regenerative medicine. As a physician, missing this chance to book a personalized hands-on training session must cost you dearly. Contact +1 305 560 5337 to book as early as possible.

AboutGlobal Stem Cells Group

Global Stem Cells Group is the parent company of six companies that are dedicated to stem cell research, solutions, and technology training. The group was founded in 2012 and combines dedicated researchers, patient educators, and physician trainers with the shared goal of meeting the need for high-end stem cell solutions and treatments.

Given that the group has a singular focus in this field, it is uniquely positioned to become the global leader in cellular medicine. In addition, by bringing together leading professionals in cellular medicine, it can discover issues that the industry faces and focus its research and development in this area. This specialization has, undoubtedly, enabled it to come up with solutions that address some of the significant issues that most stakeholders are facing in the industry.

Global Stem Cells Group is a publicly traded company operating under the symbol MSSV.https://finance.yahoo.com/quote/mssv/

Media Contact Company Name: Global Stem Cells Group Contact Person: Benito Novas Email: Send Email Phone: (305) 560-5337 Address:Datran Center 9100 S Dadeland Boulevard, Suite 1500 City: Miami State: Fl 33156 Country: United States Website: https://www.stemcellsgroup.com/

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Announcement of Training in Fort Lauderdale, Florida by The Global Stem Cells Group - Digital Journal

Stem Cell Therapy Market with 8.18% CAGR : Industry Analysis By Future Demand, Top Players, Revenue and Growth Rate Through 2027 | 112 Report Pages -…

The size of the global Stem Cell Therapy market was estimated to be USD 11910.63 in 2021 and to increase to USD 19090.47 by 2028, with a forecasted CAGR of 8.18%. The majority of companies [Pharmicell Co., Ltd, MEDIPOST Co., Ltd., Nuvasive, Inc., RTI Surgical, Inc., Holostem Terapie Avanzate S.r.l., Cytori Therapeutics, Fibrocell Science, Inc., Osiris Therapeutics, Inc., Promethera Biosciences, RTI Surgical, Inc, Celgene Corporation, Anterogen Co., Ltd.] discussed in the report have focused on expansion, investment, acquisitions, delivery focus, portfolio expansion, and brand development.

Stem Cell Therapy Market Insights 2022 By Types (Adult Stem Cells, Human Embryonic, Induced Pluripotent Stem Cells, Very Small Embryonic Like Stem Cells), Applications (Regenerative Medicine, Drug Discovery and Development), By Segmentation, Regions and Forecast to 2028. The Global Stem Cell Therapy market Report provides In-depth analysis on the market status of the Stem Cell Therapy Top manufacturers with best facts and figures, meaning, Definition, SWOT and PESTAL analysis, expert opinions and the latest developments across the globe., the Stem Cell Therapy Market Report contains Full TOC, Tables and Figures, and Chart with Key Analysis, Pre and Post COVID-19 Market Outbreak Impact Analysis and Situation by Regions.

Stem Cell Therapy Market Research Report is spread across 112 Pages and provides exclusive data, information, vital statistics, trends, and competitive landscape details in this niche sector.

The global Stem Cell Therapy market size was valued at USD 11910.63 million in 2021 and is expected to expand at a CAGR of 8.18% during the forecast period, reaching USD 19090.47 million by 2027.

Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition.Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also in use. Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions, diabetes, heart disease, and other conditions.With the ability of scientists to isolate and culture embryonic stem cells, and with scientists growing ability to create stem cells using somatic cell nuclear transfer and techniques to create induced pluripotent stem cells, controversy has crept in, both related to abortion politics and to human cloning. Additionally, efforts to market treatments based on transplant of stored umbilical cord blood have been controversial.

The report combines extensive quantitative analysis and exhaustive qualitative analysis, ranges from a macro overview of the total market size, industry chain, and market dynamics to micro details of segment markets by type, application and region, and, as a result, provides a holistic view of, as well as a deep insight into the Stem Cell Therapy market covering all its essential aspects.

For the competitive landscape, the report also introduces players in the industry from the perspective of the market share, concentration ratio, etc., and describes the leading companies in detail, with which the readers can get a better idea of their competitors and acquire an in-depth understanding of the competitive situation. Further, mergers and acquisitions, emerging market trends, the impact of COVID-19, and regional conflicts will all be considered.

In a nutshell, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the market in any manner.

The Global Stem Cell Therapy market is anticipated to rise at a considerable rate during the forecast period, between 2022 and 2028. In 2021, the market is growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Final Report will add the analysis of the impact of COVID-19 And Russia Ukraine War on this industry.

TO KNOW HOW COVID-19 PANDEMIC AND RUSSIA UKRAINE WAR WILL IMPACT THIS MARKET REQUEST SAMPLE

Moreover, it helps new businesses perform a positive assessment of their business plans because it covers a range of topics market participants must be aware of to remain competitive.

Stem Cell Therapy Market Report identifies various key players in the market and sheds light on their strategies and collaborations to combat competition. The comprehensive report provides a two-dimensional picture of the market. By knowing the global revenue of manufacturers, the global price of manufacturers, and the production by manufacturers during the forecast period of 2022 to 2028, the reader can identify the footprints of manufacturers in the Stem Cell Therapy industry.

Get a Sample PDF of report https://www.360researchreports.com/enquiry/request-sample/21612397

As well as providing an overview of successful marketing strategies, market contributions, and recent developments of leading companies, the report also offers a dashboard overview of leading companies past and present performance. Several methodologies and analyses are used in the research report to provide in-depth and accurate information about the Stem Cell Therapy Market.

Which are the prominent Stem Cell Therapy Market players across the globe?

The current market dossier provides market growth potential, opportunities, drivers, industry-specific challenges and risks market share along with the growth rate of the global Stem Cell Therapy market. The report also covers monetary and exchange fluctuations, import-export trade, and global market

status in a smooth-tongued pattern. The SWOT analysis, compiled by industry experts, Industry Concentration Ratio and the latest developments for the global Stem Cell Therapy market share are covered in a statistical way in the form of tables and figures including graphs and charts for easy understanding.

Get a Sample Copy of the Stem Cell Therapy Market Report 2022

A thorough evaluation of the restrains included in the report portrays the contrast to drivers and gives room for strategic planning. Factors that overshadow the market growth are pivotal as they can be understood to devise different bends for getting hold of the lucrative opportunities that are present in the ever-growing market. Additionally, insights into market experts opinions have been taken to understand the market better.

Report further studies the market development status and future Stem Cell Therapy Market trend across the world. Also, it splits Stem Cell Therapy market Segmentation by Type and by Applications to fully and deeply research and reveal market profile and prospects.

On the basis of product type this report displays the production, revenue, price, market share and growth rate of each type, primarily split into:

On the basis of the end users/applications this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including:

Stem Cell Therapy Market Regional Analysis:

Which region is expected to hold the highest market share in the Stem Cell Therapy Market?

Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Stem Cell Therapy in these regions, from 2015 to 2027, covering

This Stem Cell Therapy Market Research/Analysis Report Contains Answers to your following Questions

Our research analysts will help you to get customized details for your report, which can be modified in terms of a specific region, application or any statistical details. In addition, we are always willing to comply with the study, which triangulated with your own data to make the market research more comprehensive in your perspective.

Inquire more and share questions if any before the purchase on this report at https://www.360researchreports.com/enquiry/pre-order-enquiry/21612397

With tables and figures helping analyse worldwide Global Stem Cell Therapy market trends, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

Table of Content

1 Stem Cell Therapy Market Overview 1.1 Product Overview and Scope of Stem Cell Therapy Market 1.2 Stem Cell Therapy Market Segment by Type 1.2.1 Global Stem Cell Therapy Market Sales Volume and CAGR (%) Comparison by Type (2017-2027) 1.3 Global Stem Cell Therapy Market Segment by Application 1.3.1 Stem Cell Therapy Market Consumption (Sales Volume) Comparison by Application (2017-2027) 1.4 Global Stem Cell Therapy Market, Region Wise (2017-2027) 1.4.1 Global Stem Cell Therapy Market Size (Revenue) and CAGR (%) Comparison by Region (2017-2027) 1.4.2 United States Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.3 Europe Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.4 China Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.5 Japan Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.6 India Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.7 Southeast Asia Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.8 Latin America Stem Cell Therapy Market Status and Prospect (2017-2027) 1.4.9 Middle East and Africa Stem Cell Therapy Market Status and Prospect (2017-2027) 1.5 Global Market Size of Stem Cell Therapy (2017-2027) 1.5.1 Global Stem Cell Therapy Market Revenue Status and Outlook (2017-2027) 1.5.2 Global Stem Cell Therapy Market Sales Volume Status and Outlook (2017-2027) 1.6 Global Macroeconomic Analysis 1.7 The impact of the Russia-Ukraine war on the Stem Cell Therapy Market

2 Industry Outlook 2.1 Stem Cell Therapy Industry Technology Status and Trends 2.2 Industry Entry Barriers 2.2.1 Analysis of Financial Barriers 2.2.2 Analysis of Technical Barriers 2.2.3 Analysis of Talent Barriers 2.2.4 Analysis of Brand Barrier 2.3 Stem Cell Therapy Market Drivers Analysis 2.4 Stem Cell Therapy Market Challenges Analysis 2.5 Emerging Market Trends 2.6 Consumer Preference Analysis 2.7 Stem Cell Therapy Industry Development Trends under COVID-19 Outbreak 2.7.1 Global COVID-19 Status Overview 2.7.2 Influence of COVID-19 Outbreak on Stem Cell Therapy Industry Development

3 Global Stem Cell Therapy Market Landscape by Player 3.1 Global Stem Cell Therapy Sales Volume and Share by Player (2017-2022) 3.2 Global Stem Cell Therapy Revenue and Market Share by Player (2017-2022) 3.3 Global Stem Cell Therapy Average Price by Player (2017-2022) 3.4 Global Stem Cell Therapy Gross Margin by Player (2017-2022) 3.5 Stem Cell Therapy Market Competitive Situation and Trends 3.5.1 Stem Cell Therapy Market Concentration Rate 3.5.2 Stem Cell Therapy Market Share of Top 3 and Top 6 Players 3.5.3 Mergers and Acquisitions, Expansion

4 Global Stem Cell Therapy Sales Volume and Revenue Region Wise (2017-2022) 4.1 Global Stem Cell Therapy Sales Volume and Market Share, Region Wise (2017-2022) 4.2 Global Stem Cell Therapy Revenue and Market Share, Region Wise (2017-2022) 4.3 Global Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.4 United States Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.4.1 United States Stem Cell Therapy Market Under COVID-19 4.5 Europe Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.5.1 Europe Stem Cell Therapy Market Under COVID-19 4.6 China Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.6.1 China Stem Cell Therapy Market Under COVID-19 4.7 Japan Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.7.1 Japan Stem Cell Therapy Market Under COVID-19 4.8 India Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.8.1 India Stem Cell Therapy Market Under COVID-19 4.9 Southeast Asia Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.9.1 Southeast Asia Stem Cell Therapy Market Under COVID-19 4.10 Latin America Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.10.1 Latin America Stem Cell Therapy Market Under COVID-19 4.11 Middle East and Africa Stem Cell Therapy Sales Volume, Revenue, Price and Gross Margin (2017-2022) 4.11.1 Middle East and Africa Stem Cell Therapy Market Under COVID-19

5 Global Stem Cell Therapy Sales Volume, Revenue, Price Trend by Type 5.1 Global Stem Cell Therapy Sales Volume and Market Share by Type (2017-2022) 5.2 Global Stem Cell Therapy Revenue and Market Share by Type (2017-2022) 5.3 Global Stem Cell Therapy Price by Type (2017-2022) 5.4 Global Stem Cell Therapy Sales Volume, Revenue and Growth Rate by Type (2017-2022) 5.4.1 Global Stem Cell Therapy Sales Volume, Revenue and Growth Rate of Adult Stem Cells (2017-2022) 5.4.2 Global Stem Cell Therapy Sales Volume, Revenue and Growth Rate of Human Embryonic (2017-2022) 5.4.3 Global Stem Cell Therapy Sales Volume, Revenue and Growth Rate of Induced Pluripotent Stem Cells (2017-2022) 5.4.4 Global Stem Cell Therapy Sales Volume, Revenue and Growth Rate of Very Small Embryonic Like Stem Cells (2017-2022)

6 Global Stem Cell Therapy Market Analysis by Application 6.1 Global Stem Cell Therapy Consumption and Market Share by Application (2017-2022) 6.2 Global Stem Cell Therapy Consumption Revenue and Market Share by Application (2017-2022) 6.3 Global Stem Cell Therapy Consumption and Growth Rate by Application (2017-2022) 6.3.1 Global Stem Cell Therapy Consumption and Growth Rate of Regenerative Medicine (2017-2022) 6.3.2 Global Stem Cell Therapy Consumption and Growth Rate of Drug Discovery and Development (2017-2022)

7 Global Stem Cell Therapy Market Forecast (2022-2027) 7.1 Global Stem Cell Therapy Sales Volume, Revenue Forecast (2022-2027) 7.1.1 Global Stem Cell Therapy Sales Volume and Growth Rate Forecast (2022-2027) 7.1.2 Global Stem Cell Therapy Revenue and Growth Rate Forecast (2022-2027) 7.1.3 Global Stem Cell Therapy Price and Trend Forecast (2022-2027) 7.2 Global Stem Cell Therapy Sales Volume and Revenue Forecast, Region Wise (2022-2027) 7.2.1 United States Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.2 Europe Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.3 China Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.4 Japan Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.5 India Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.6 Southeast Asia Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.7 Latin America Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.2.8 Middle East and Africa Stem Cell Therapy Sales Volume and Revenue Forecast (2022-2027) 7.3 Global Stem Cell Therapy Sales Volume, Revenue and Price Forecast by Type (2022-2027) 7.3.1 Global Stem Cell Therapy Revenue and Growth Rate of Adult Stem Cells (2022-2027) 7.3.2 Global Stem Cell Therapy Revenue and Growth Rate of Human Embryonic (2022-2027) 7.3.3 Global Stem Cell Therapy Revenue and Growth Rate of Induced Pluripotent Stem Cells (2022-2027) 7.3.4 Global Stem Cell Therapy Revenue and Growth Rate of Very Small Embryonic Like Stem Cells (2022-2027) 7.4 Global Stem Cell Therapy Consumption Forecast by Application (2022-2027) 7.4.1 Global Stem Cell Therapy Consumption Value and Growth Rate of Regenerative Medicine(2022-2027) 7.4.2 Global Stem Cell Therapy Consumption Value and Growth Rate of Drug Discovery and Development(2022-2027) 7.5 Stem Cell Therapy Market Forecast Under COVID-19

8 Stem Cell Therapy Market Upstream and Downstream Analysis 8.1 Stem Cell Therapy Industrial Chain Analysis 8.2 Key Raw Materials Suppliers and Price Analysis 8.3 Manufacturing Cost Structure Analysis 8.3.1 Labor Cost Analysis 8.3.2 Energy Costs Analysis 8.3.3 RandD Costs Analysis 8.4 Alternative Product Analysis 8.5 Major Distributors of Stem Cell Therapy Analysis 8.6 Major Downstream Buyers of Stem Cell Therapy Analysis 8.7 Impact of COVID-19 and the Russia-Ukraine war on the Upstream and Downstream in the Stem Cell Therapy Industry

9 Players Profiles 9.1 Pharmicell Co., Ltd 9.1.1 Pharmicell Co., Ltd Basic Information, Manufacturing Base, Sales Region and Competitors 9.1.2 Stem Cell Therapy Product Profiles, Application and Specification 9.1.3 Pharmicell Co., Ltd Market Performance (2017-2022) 9.1.4 Recent Development 9.1.5 SWOT Analysis 9.2 MEDIPOST Co., Ltd. 9.2.1 MEDIPOST Co., Ltd. Basic Information, Manufacturing Base, Sales Region and Competitors 9.2.2 Stem Cell Therapy Product Profiles, Application and Specification 9.2.3 MEDIPOST Co., Ltd. Market Performance (2017-2022) 9.2.4 Recent Development 9.2.5 SWOT Analysis 9.3 Nuvasive, Inc. 9.3.1 Nuvasive, Inc. Basic Information, Manufacturing Base, Sales Region and Competitors 9.3.2 Stem Cell Therapy Product Profiles, Application and Specification 9.3.3 Nuvasive, Inc. Market Performance (2017-2022) 9.3.4 Recent Development 9.3.5 SWOT Analysis 9.4 RTI Surgical, Inc. 9.4.1 RTI Surgical, Inc. Basic Information, Manufacturing Base, Sales Region and Competitors 9.4.2 Stem Cell Therapy Product Profiles, Application and Specification 9.4.3 RTI Surgical, Inc. Market Performance (2017-2022) 9.4.4 Recent Development 9.4.5 SWOT Analysis 9.5 Holostem Terapie Avanzate S.r.l. 9.5.1 Holostem Terapie Avanzate S.r.l. Basic Information, Manufacturing Base, Sales Region and Competitors 9.5.2 Stem Cell Therapy Product Profiles, Application and Specification 9.5.3 Holostem Terapie Avanzate S.r.l. Market Performance (2017-2022) 9.5.4 Recent Development 9.5.5 SWOT Analysis 9.6 Cytori Therapeutics 9.6.1 Cytori Therapeutics Basic Information, Manufacturing Base, Sales Region and Competitors 9.6.2 Stem Cell Therapy Product Profiles, Application and Specification 9.6.3 Cytori Therapeutics Market Performance (2017-2022) 9.6.4 Recent Development 9.6.5 SWOT Analysis 9.7 Fibrocell Science, Inc. 9.7.1 Fibrocell Science, Inc. Basic Information, Manufacturing Base, Sales Region and Competitors 9.7.2 Stem Cell Therapy Product Profiles, Application and Specification 9.7.3 Fibrocell Science, Inc. Market Performance (2017-2022) 9.7.4 Recent Development 9.7.5 SWOT Analysis 9.8 Osiris Therapeutics, Inc. 9.8.1 Osiris Therapeutics, Inc. Basic Information, Manufacturing Base, Sales Region and Competitors 9.8.2 Stem Cell Therapy Product Profiles, Application and Specification 9.8.3 Osiris Therapeutics, Inc. Market Performance (2017-2022) 9.8.4 Recent Development 9.8.5 SWOT Analysis 9.9 Promethera Biosciences 9.9.1 Promethera Biosciences Basic Information, Manufacturing Base, Sales Region and Competitors 9.9.2 Stem Cell Therapy Product Profiles, Application and Specification 9.9.3 Promethera Biosciences Market Performance (2017-2022) 9.9.4 Recent Development 9.9.5 SWOT Analysis 9.10 RTI Surgical, Inc 9.10.1 RTI Surgical, Inc Basic Information, Manufacturing Base, Sales Region and Competitors 9.10.2 Stem Cell Therapy Product Profiles, Application and Specification 9.10.3 RTI Surgical, Inc Market Performance (2017-2022) 9.10.4 Recent Development 9.10.5 SWOT Analysis 9.11 Celgene Corporation 9.11.1 Celgene Corporation Basic Information, Manufacturing Base, Sales Region and Competitors 9.11.2 Stem Cell Therapy Product Profiles, Application and Specification 9.11.3 Celgene Corporation Market Performance (2017-2022) 9.11.4 Recent Development 9.11.5 SWOT Analysis 9.12 Anterogen Co., Ltd. 9.12.1 Anterogen Co., Ltd. Basic Information, Manufacturing Base, Sales Region and Competitors 9.12.2 Stem Cell Therapy Product Profiles, Application and Specification 9.12.3 Anterogen Co., Ltd. Market Performance (2017-2022) 9.12.4 Recent Development 9.12.5 SWOT Analysis

10 Research Findings and Conclusion

11 Appendix 11.1 Methodology 11.2 Research Data Source

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Jcr Pharmaceuticals Co., Ltd. and Sysmex Establish A Joint Venture in the Field of Regenerative Medicine and Cell Therapy – Marketscreener.com

JCR Pharmaceuticals Co., Ltd. and Sysmex Corporation announced that they have established a joint venture (hereafter the "joint venture") for carrying out research and development, manufacture and sales of cell-based regenerative medicine products including hematopoietic stem cells and other stem cells. In recent years, the significant potential of regenerative medicine and cell therapy have been established in particular in areas that have traditionally been difficult to address with conventional chemically synthesized low molecular weight drugs1 or biopharmaceuticals2, such as the restoration of tissues and functions lost as a result of aging, illness, autoimmune diseases, or cancer. In particular, research and development on the therapeutic application of stem cells including hematopoietic stem cells, mesenchymal stem cells, and iPS cells have generated significant attention. Since its inception, JCR has been engaged in the research, development, manufacturing and sales of pharmaceutical products using regenerative medicine, genetic engineering, and gene therapy technologies to advance therapies in the rare disease field. This is exemplified in the field of regenerative medicine, by the approval of TEMCELL HS Inj.3, the first allogeneic regenerative medicine in Japan (Non-proprietary name: Human (allogeneic) bone marrow-derived mesenchymal stem cells) in February 2016 for the treatment of acute graft-versus-host disease (acute GVHD)4, a serious complication that develops after hematopoietic stem cell transplantation. In recent years, JCR has further streamlined and integrated its expertise around the establishment of groundbreaking medicines for the advancement of highly innovative medicines that could not be developed without such groundbreaking technologies. In the joint venture, the two companies aim to realize the social implementation of regenerative medicine and cell therapy by integrating JCR's expertise in developing, manufacturing and marketing regenerative medicine products, with Sysmex's expertise in quality control testing technology and knowledge of workflows efficiency using robotics technology, including IoT. AlliedCel Corporation, which is the corporate name of the joint venture following prior discussions regarding the alliance both companies, was established on October 3, 2022. The joint venture will advance programs of the potential for technology development and commercialization, including the project currently being promoted by both companies using hematopoietic stem cell proliferation technology. The name AlliedCel stands for the joint venture's aspiration to integrate knowledge and expertise from a broad set of collaborators and stakeholders including business partners, patients and their families, with the united goal of unleashing the power of cells in supporting patients in their need for life-changing therapies. Through the research and development of regenerative medicine products using diverse cells such as stem cells, AlliedCel aims to provide appropriate treatment options to patients and improve their prognosis.

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Jcr Pharmaceuticals Co., Ltd. and Sysmex Establish A Joint Venture in the Field of Regenerative Medicine and Cell Therapy - Marketscreener.com

ANDREWS MEDICINE AND CELLTEX THERAPEUTICS CORPORATION JOIN FORCES TO BRING CUTTING EDGE TECHNOLOGIES TO ATHLETIC INJURIES – PR Newswire

HOUSTON, Oct. 4, 2022 /PRNewswire/ -- James R. "Jim" Andrews, MD, Chairman and CEO of Andrews Medicine of Pensacola, Florida, and David G. Eller, Chairman and CEO of Celltex Therapeutics Corporation of Houston, Texas, announced today that together they will form a new biotechnology company to bridge the divide between stem cell research and the current treatment of athletic injuries. The jointly owned company will operate under the name of "Andrews Celltex Biologics".

The new company will undertake the operation of a Sports Injury Program that includes the Celltex-sponsored FDA developmental study associated with its Investigational New Drug (IND) for the use of Celltex-produced autologous Mesenchymal Stem Cells (MSCs) in the treatment of orthopedic indications. Andrews Medicine will participate in this FDA observed IND research study and will be responsible for selection of participants and administration for this new study. The new venture promises to bring the best medical orthopedic practices of Andrews Medicine for treatment of sports injuries with best practices of Celltex for production of therapeutic quality autologous MSCsas a regenerative component of the treatment. Andrews Celltex Biologics will break new ground with this combined effort. The goal is an FDA approved Biologic License for this Celltex product.

Dr. Andrews said: "I have always known that stem cells, when properly handled, can add value to already effective treatments of inflammatory conditions caused by injury or disease. I am delighted that the FDA has been working with Celltex for studying the safety and efficacy of this combination of Celltex-produced MSCs with traditional medical treatment of multiple sports injury indications. Our know-how and network of sports teams and physicians will add immediate value to our new joint company. I am convinced that Andrews Celltex Biologics will be a leader in this huge growth sector of health care coupled with regenerative medicine."

"Celltex is excited about the opportunity to join forces with one of the best orthopedic and sports medicine companies in the country," said David G. Eller, Chairman and CEO of Celltex. "It is a perfect match. Surgical treatments coupled with Celltex-produced regenerative MSCs will improve recovery time and remediation. This joint effort of the two leading companies in their field will bring cutting edge regenerative health care for sports injuries and beyond."

David Eller continued, "Over the past 11 years, Celltex has developed unique know-how and proprietary technology to produce, in its specially designed cGMP lab, millions of MSCs from a small extraction of a person's adipose tissue. The integrity and vibrancy of the MSCs are of therapeutic quality. Over one trillion MSCs have been produced by Celltex, in its cGMP lab, from individuals wanting their own stem cells reintroduced into their bodies by medical doctors to fight a variety of diseases, especially those caused by inflammatory conditions. Given the autologous nature of Celltex-produced stem cells, there have been no severe adverse events when these stem cells have been reintroduced into the individuals from whom the small, one-time adipose tissue sample had been extracted."

ABOUT ANDREWS MEDICINE OF PENSACOLA, FLORIDA

Andrews Medicine is an integrated healthcare platform built on five decades of research, innovation, and clinical expertise led by internationally recognized orthopaedic surgeon, Dr. James "Jim" Andrews. Widely known as the surgeon for elite athletes from around the world, Dr. Andrews is also a pioneering thought leader in the field of research, injury prevention, new surgical techniques, and practice management. Andrews Medicine brings this experience and expertise to healthcare systems, medical providers, sports organizations, and the communities they serve, ensuring that every patient has access to exceptional clinical care. Read more at: http://www.andrewsmedicine.com

ABOUT CELLTEX THERAPEUTICS CORPORATION

Founded in 2011, Celltex Therapeutics Corporation is a Houston, Texas-based biotechnology company that specializes in the manufacturing and cryopreservation of Mesenchymal Stem Cells (MSCs).Celltex is a leading commercial provider of autologous MSCs for therapeutic use. The Company uses its proprietary technology to isolate, cryopreserve and culture billions of undifferentiated and genetically stable MSCs in its state-of-the-art current Good Manufacturing Practices (cGMP)-compliant laboratory.The Company is dedicated to pioneering technological breakthroughs in regenerative medicine. For more information see: http://www.celltexbank.com

SOURCE Celltex Therapeutics Corporation

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ANDREWS MEDICINE AND CELLTEX THERAPEUTICS CORPORATION JOIN FORCES TO BRING CUTTING EDGE TECHNOLOGIES TO ATHLETIC INJURIES - PR Newswire

Regenerative Medicine For Heart Diseases: How It Is Better Than Conventional Treatments | TheHealthSite.co – TheHealthSite

The future possibilities of regenerative Medicine are endless. Know how regenerative medicine for heart diseases is better than conventional treatments.

Written by Longjam Dineshwori | Updated : October 5, 2022 9:52 AM IST

In the past few days, news of people dying due to cardiac arrest and heart attack during the festivities have been making headlines. Concerningly, increasing number of younger people, precisely adults who are in their 30s, are getting heart problems today. Health experts have been advising people to maintain a healthy lifestyle to prevent heart diseases or at least delay their onset. Also, tremendous advancements have been made in the field of cardiology making treatment of heart ailments more effective and less invasive. One of them is regenerative medicine, which is now being explored for the treatment of several diseases.

Get to more about regenerative medicine and its possibilities for treating heart diseases from Dr Pradeep Mahajan, Regenerative Medicine Researcher, Stem Rx Bioscience Solutions Pvt. Ltd, Navi Mumbai.

An alarming one out of four deaths in our country today is due to heart disease. This is largely due to our sedentary lifestyles, unhealthy eating habits, and stress. Barring the heart conditions that are present from birth (congenital) or that are passed down through the generations (inherited), heart diseases can be prevented or at least the onset can be delayed by maintaining a healthy lifestyle.

The field of cardiology (relating to the heart) has advanced tremendously, and there are several medications and surgical procedures that help patients maintain the functions of the heart. However, these call for invasive treatments and the need for life-long medications. Moreover, the side effects of medicines should also be taken into account.

Enter the field of Regenerative Cardiology! As the word suggests, this branch refers to utilising the natural healing potential of the body to repair and re-grow damaged heart tissues. Stem cells have been researched in several heart diseases to overcome the damage to the heart and facilitate healing. Not just stem cells, but cell-based products like exosomes, molecular chaperones, growth factors etc. have shown promise as well. Do not think about the technicalities, all these molecules are present in our body and researchers and clinicians are now working on how to apply these for the treatment of several diseases.

Commonly, we hear of blocks in the heart, infection, and weak muscles of the heart that do not pump blood properly leading to various diseases. With cell-based therapies, we can tackle each of these issues. Stem cells (the most basic 'unspecialized' cells of our body) can multiply and form various cells of the body, including heart cells. Similarly, cell products like exosomes are cargo packets they carry the required substances for repair and re-growth of tissues. These biological molecules have 'housekeeping functions, meaning that they ensure that any unwanted product and even bacteria/viruses are removed periodically from the body.

The possibilities of Regenerative Medicine for heart diseases are many blocks in the heart can be dissolved, blood supply can be improved, heart muscles can be strengthened, etc. because these biological molecules are capable of reducing inflammation (swelling) in the body, modify the immune system to function better, enhance the functions of other cells, etc. Since these are part of our own body, providing these molecules in the appropriate quantity at the desired site will enhance healing without side effects. In fact, there is ongoing research on growing healthy heart tissue in labs with these biological molecules to transplant them into the human body. Who knows, someday the whole heart might be grown in a lab! While the future possibilities are endless, the current cell-based therapies can be a definitive addition to enhance the outcomes of existing conventional treatments. Of course, rehabilitation and lifestyle modifications are mandatory to maintain the results.

A holistic approach is important one cannot simply rely on symptom management the core issues have to be targeted and Regenerative Medicine can do just that. The death rate due to heart disease can be reduced and patients will be able to have a better quality of life.

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Second-Line BCL Treatment Landscape Shifts From ASCT to CAR T-Cell Therapy – Targeted Oncology

Hematologic malignancies have been impacted heavily by the introduction of chimeric antigen receptor (CAR) T-cell therapy, which has demonstrated long remission in major clinical trials and received approvals by the FDA. CAR T-cell therapy provides a new option for patients with relapsed/refractory B-cell lymphoma (BCL).

The current treatment landscape for patients with relapsed/refractory [BCL] looks extremely promising, thanks to the positive results from clinical trials and thus the subsequent FDA approvals of these therapeutics, Manali Kamdar, MD, associate professor of medicine-hematology and clinical director of lymphoma services at the University of Colorado Medicine in Aurora, said in an interview with the SOHO Daily News beforethe 10th Annual Meeting of the Society of Hematologic Oncology (SOHO 2022).

Kamdars presentation on September 30, 2022, at 1:40 pm during the conference concerns the question of when to use CAR T-cell therapy vs autologous stem cell transplant (ASCT) in patients with relapsed/refractory aggressive BCL. She says the 3 phase 3 studies of CAR T-cell products that were presented at the 2021 American Society of Hematology Annual Meeting and Exposition (ASH 2021) have made a major difference in answering this question for high-risk patients.

Patients with diffuse large BCL who relapse within 12 months of frontline chemoimmunotherapy with R-CHOP (rituximab [Rituxan], cyclophosphamide, doxorubicin, vincristine [Oncovin], prednisone) are considered primary refractory, and these patients have very poor outcomes. In the past, they would receive salvage chemotherapy followed by an ASCT. Kamdar says only a quarter of these high-risk patients would achieve long-term remission following ASCT.

This led to an urgent need for CAR T-cell therapy in the second line for these patients. CAR T cells had shown efficacy for R/R BCL, leading to the approval of these therapies in patients with at least 2 prior lines of treatment, the first being axicabtagene ciloleucel (axi-cel; Yescarta) in 2017.1,2

The results of 3 pivotal phase 3 trials of CAR T-cell products were first presented at ASH 2021, comparing them with salvage chemotherapy and ASCT in patients with aggressive non-Hodgkin BCL who relapsed within 12 months of frontline chemoimmunotherapy. The ZUMA-7 trial (NCT03391466) that evaluated axi-cel and the TRANSFORM trial (NCT03575351) that evaluated lisocabtagene maraleucel (liso-cel; Breyanzi) showed significantly higher event-free survival (EFS) rates in patients who received CAR T-cell therapy vs ASCT, but the BELINDA trial (NCT03570892) that evaluated tisagenlecleucel (tisa-cel; Kymriah) failed to show improved EFS over standard-of-care second-line therapy.3-5 Kamdar plans to discuss the possible reasons for the different outcomes of these trials in greater detail in her presentation.

With axi-cel and liso-cel receiving FDA approvals as second-line therapy, CAR T-cell therapy stands to replace ASCT in this stage of sequencing.6,7 Within this high-risk R/R large BCL subset, I will have to say I no longer recommend an ASCT based on these 2 positive studies, and that we take patients to CAR T-cell therapy, Kamdar said.

Kamdars presentation will focus on the outcomes demonstrated by these trials, including the statistically significant EFS, progression-free survival, and complete response rate of CAR T-cell therapy. Additionally, she will discuss the manageable levels of toxicity seen in the 2 positive trials, with no grade 4 or 5 cytokine release syndrome or neurotoxicity being reported. Longer follow-up is needed to observe overall survival outcomes and other long-term impacts of these therapies.

Despite these results, CAR T-cell therapy is not an option for those who are chemotherapy-sensitive who relapsed more than 12 months after frontline therapy. Currently, ASCT remains the standard of care, Kamdar said. But itd be nice to see [whether] there is something else that can actually be better.

Additionally, the role of CAR T-cell therapy is being investigated in patients who are transplant-ineligible in the phase 2 TRANSCEND-PILOT 017006 study (NCT03483103) that evaluates liso-cel. Durable responses to liso-cel were reported in the primary analysis presented at the 2022 American Society of Clinical Oncology Annual Meeting.8

For patients with high-risk R/R BCL, Kamdar says its crucial to start referring patients for CAR T-cell therapy as soon as they are determined to be primary refractory. CAR T-cell therapy is certainly a process that takes time, because manufacturing of the cells requires a minimum of 17 to 34 days based on the construct you choose, she said. Additionally, insurance approvals and logistical concerns can cause further delays to starting therapy. CAR T-cell production time and accessibility may be improved by new approaches that are being investigated, including allogeneic CAR T cells that do not require patients to undergo leukapheresis.

One rising area of need is therapies for patients who fail CAR T-cell therapy, who may have limited treatment options if they are CD19 negative. Kamdar anticipates that novel therapies, including bispecific antibodies, bispecific T-cell engagers, and natural killer T cells, could fill this unmet need in patients with R/R BCL. [Approximately] 20% of patients [in recent trials of bispecific agents] may have actually received prior CAR T-[cell therapy], and they are showing a response in patients who have failed prior CAR T-cell therapy, she said.

She suggests novel time-limited bispecific therapies will not only benefit those who relapsed or who cannot receive CAR T-cell therapy, but they are also valuable for physicians who want to treat patients while waiting to start CAR T-cell therapy.

Kamdar is looking forward to discussing the shift from ASCT to CAR T-cell therapy in second-line therapy in greater detail at SOHO 2022. Im very excited to see all my colleagues after so long, Kamdar said. Im thrilled to be able to connect in person with everyone. Its been too long.

REFERENCES:

1. Schuster SJ, Svoboda J, Chong EA, et al. Chimeric antigen receptor T cells in refractory B-cell lymphomas.N Engl J Med. 2017;377(26):2545-2554. doi:10.1056/NEJMoa1708566

2. FDA approves CAR-T cell therapy to treat adults with certain types of large B-cell lymphoma. News release. FDA; October 18, 2017. Updated March 21, 2018. Accessed August 25, 2022. https://bit.ly/3ANA0k5

3. Locke FL, Miklos DB, Jacobson CA, et al. Axicabtagene ciloleucel as second-line therapy for large B-cell lymphoma.N Engl J Med. 2022;386(7):640-654. doi:10.1056/NEJMoa2116133

4. Kamdar M, Solomon SR, Arnason J, et al. Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma (TRANSFORM): results from an interim analysis of an open-label, randomised, phase 3 trial. Lancet. 2022;399(10343):2294-2308. Published correction appears in Lancet. 2022;400(10347):160.

5. Bishop MR, Dickinson M, Purtill D, et al. Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.N Engl J Med. 2022;386(7):629-639. doi:10.1056/NEJMoa2116596

6. FDA approves axicabtagene ciloleucel for second-line treatment of large B-cell lymphoma. FDA. April 1, 2022. Accessed August 25, 2022. https://bit.ly/3ANmZab

7. FDA approves lisocabtagene maraleucel for second-line treatment of large B-cell lymphoma. FDA. June 24, 2022. Accessed August 25, 2022. https://bit.ly/3Q52NVT

8. Seghal A, Hoda D, Riedell PA, et al. Lisocabtagene maraleucel (liso-cel) as second-line (2L) therapy for R/R large B-cell lymphoma (LBCL) in patients (pt) not intended for hematopoietic stem cell transplantation (HSCT): primary analysis from the phase 2 PILOT study. J Clin Oncol. 2022;40(suppl 16):7062. doi:10.1200/JCO.2022.40.16_suppl.7062

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Second-Line BCL Treatment Landscape Shifts From ASCT to CAR T-Cell Therapy - Targeted Oncology

Dr. Tania Small Appointed to the Board of Governors of the Accreditation Council for Medical Affairs – citybiz

Dr. Tania Small, MD

NEW YORK(BUSINESS WIRE)The Accreditation Council for Medical Affairs announces the appointment of Tania Small, MD, Global Head of Oncology Medical Affairs and Chair of R&D Diversity, Equity, and Inclusion Council at GSK, to its board of governors today.

The ACMA has both US and international presence in over 80 countries. It is highly recognized for its accredited board certification, and the Board-Certified Medical Affairs Specialist (BCMAS) program designed for pharmaceutical industry medical affairs and medical science liaison (MSL) professionals. Additionally, the ACMA is regarded as the pre-eminent thought leader in US and global medical affairs.

Through her leadership, Dr. Tania Small will make a significant contribution to the mission of ACAM as we continue to raise the bar for pharmaceutical executives with a focus on Medical Affairs and Medical Science Liaisons (MSLs).

We are honored to have Dr. Small join the ACMA Board. Tania is a highly respected professional in the life sciences industry. She is known for driving innovation that improves the experience and supports better outcomes of people living with cancer, said Dr. William Soliman, CEO and Founder of ACMA.

Dr. Small will play a critical role in helping to expand the mission of the ACMA in the life sciences industry. ACMA will continue to collaborate with the government, healthcare policy consortiums, pharmaceutical companies, and patient advocacy organizations to ensure that the ACMA continues to operate at the highest standards of ethics and compliance to achieve this broader mission.

I am honored to be joining the ACMA Board of Governors. They have been instrumental in positively shaping healthcare policy and dialogue. The ACMA is bringing forth a new era in the pharmaceutical industry by providing credible board certification for medical affairs / MSL professionals. An ACMA accreditation enhances MSL professionals ability to deliver upon their critical mission to healthcare providers and patients in need, said Dr. Small.

About Dr. Tania SmallTania Small, Global Head of Oncology Medical Affairs and Chair of R&D Diversity, Equity, and Inclusion Council at GSK, has built and leads an organization of medical professionals focused on patient-driven science. She is passionate about creating groundbreaking solutions that will successfully deliver transformational medicines and access mechanisms, which are needed to revolutionize both the experience and outcomes of people living with cancer and their treatment teams.

A board-certified pediatric hematologist/oncologist, Dr. Small has deep experience in clinical research and drug development. She was trained in hematology/oncology and bone marrow transplantation at Columbia University, where she also completed a genetic research fellowship. She subsequently continued her focus on both hematology and stem cell transplant at New York Presbyterian Hospital and received several grants for her translational research in gene therapy and regenerative medicine.

In previous roles with Novartis Oncology and Ipsen, Dr. Small successfully led the launch of multiple oncology therapies while overseeing programs for both clinical development and medical affairs. She has also led many patient-centered and diversity programs, working closely with the US FDA, Congress, and the American Society of Clinical Oncology (ASCO) to improve the diversity of enrollment in oncology clinical trials and elderly programs.

About Accreditation Council for Medical Affairs (ACMA)The Accreditation Council for Medical Affairs (ACMA) is highly regarded for its Board-Certified Medical Affairs Specialist (BCMAS) program. It is the worlds first and only board certification for MSL and medical affairs professionals. The ACMA offers a 360 suite of digital solutions for the life sciences industry, including market research, sentiment analysis, CRM tools, and more. The ACMA has the first ever Prior Authorization Certification Specialist (PACS) program to help streamline healthcare insurance hurdles. For more information, visit:www.medicalaffairsspecialist.org

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Dr. Tania Small Appointed to the Board of Governors of the Accreditation Council for Medical Affairs - citybiz