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How to Fight Fine Lines and Wrinkles, the K-beauty Way | Expert Insight, Product Recommendations – Allure

Korean dermatologists inject neurotoxins in a variety of different ways beyond what we are accustomed to in America. As Allure has often reported, Skin Botox is an extremely in-demand procedure in Seoul. Shallow pricks of botulism neurotoxins are inserted all over the face just below the surface for more of a smoothing effect than a muscle-freezing one. (You can check out our in-depth guide to Skin Botox.) Baby Botox is also a popular preventative option among younger patients, Dr. Chang says.

Botox is often used to lift jawlines and the corners of the mouth, says Cho Yun Joo, a board-certified dermatologist based in Seoul. The latter is done because the mouth is prone to drooping as we age. And Sang Wook Lee, a board-certified dermatologist at Seoul's Yezel Clinic, tells Allure that he also uses Botox to lift droopy undereye areas and give patients incredibly subtle facelifts. "I put it near the scalp to lift the face," he adds.

PRP

Skin Botox is often combined with platelet-rich plasma (PRP) therapy, a.k.a. a vampire facial, at Dr. Lee's clinic. Many of the Korean dermatologists I've interviewed over the years have lauded PRP's uncanny ability to improve fine lines and wrinkles and have called it the future of skin care. You can dive into the blood-based process here.

Sculptra

In December 2021, the U.S. Food and Drug Administration (FDA) approved the aesthetic use of Sculptra, a poly-L-lactic acid-based biostimulant that triggers the natural process of collagen production, to iron out fine lines and wrinkles. Prior to that, the FDA allowed it to be used only as a treatment for HIV patients experiencing lipoatrophy, or severe fat loss, in the face,Michael Somenek, MD, a Washington, DC-based, board-certified facial plastic surgeon and participant in the recent FDA study trials, told Allure. However, in Korea, it's long been another beloved injectable option alongside its Korean equivalents. Sculptra is often administered into nasolabial folds (or smile lines) and other areas of concern to boost collagen cell regrowth, Dr. Lee says. "The good thing about this is that it has long-term effects lasting up to three years," he adds.

People in Korea are less into facial fillers and favor injectables that replenish and boost collagen production on a cellular level, like Sculptra, Dr. Lee says. Consequently, hyaluronic acid-filled syringes, like Restylane and Juvderm, are more likely used to help moisturize the skin on a cellular level. (This procedure is nicknamed the "water glow injection.") In America, we are more accustomed to using them to augment and plump faces.

Skin Boosters

Koreans are also all about what's often called "skin booster shots," which do just that. I like to think of them as superpowered versions of my favorite skin-care products mainlined directly into my skin cells. I received the most popular skin booster the Chanel injection the last time I traveled to Seoul. Professionally known as Filoga 135, this shot is infused with amino acids, hyaluronic acid, and vitamins A, B, C, and E and injected all over the face for brighter, plumper skin in two weeks. It also helps stimulate collagen production for about three to four months.

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How to Fight Fine Lines and Wrinkles, the K-beauty Way | Expert Insight, Product Recommendations - Allure

‘Almost crawling to the bathroom’: Kentucky’s Kellan Grady reveals that he played through severe foot pain – The Athletic

After a once-promising season suddenly burst into flames, the same question we keep asking about Kentucky basketball in general also applies specifically to Kellan Grady, who was the Wildcats most reliable outside shooter until he wasnt. When Saint Peters delivered an unthinkable first-round NCAA Tournament upset, dazed and confused fans were left to wonder of both their team and its wayward marksman: What the hell just happened?

But thats the thing. It didnt just happen. Several things, over time, conspired against Grady and Kentucky. There was Sahvir Wheelers concussion (or maybe two). TyTy Washingtons ankle. Wheelers wrist. Washingtons ankle again. And again. Those injuries were widely reported. Heres one that wasnt: Both of Gradys feet were plagued by plantar fasciitis for months and got progressively worse under the heavy load he carried while the Wildcats other two starting guards struggled to stay on the court.

This actually started in June, Grady tells The Athletic. I knew then. But the only way to get rid of it fully is rest. If you have it bad, its like six weeks of rest. I needed to earn my spot. It was very competitive in the summer and fall. Especially in the fall, right when we started up again, I wasnt playing my best and I felt like I couldnt afford to take a bunch of time off to rest my feet. So I just decided to fight through it. Then once the season started, there was no way I was missing any games.

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'Almost crawling to the bathroom': Kentucky's Kellan Grady reveals that he played through severe foot pain - The Athletic

Anti-aging treatments by experts for women in their 40’s – India TV News

Image Source : FREEPIK

Anti-aging treatments by experts for women in their 40's

As we age there are many problems which we start to see especially in the face region. The two main issues that happen are sagging and loss of volume. Plus there are wrinkles that are seen on the forehead and side of the eyes giving a tired look to the face. If any person has a loss of volume this causes the face to look droopy. The options to restore volume are either HA (hyaluronic acid) fillers, which are a gel-like substance or our own fat.

These HA fillers last for 10-12 months and slowly dissolve in the body and need to be done again. Fat remains for 3-4 years at least and gives a very good improvement in skin texture as well!

Sagging happens as we age due to tissues losing their tone. There is a constant process of sagging that starts from the 30s and goes up as we age. The latest treatment option for correcting the sagging is by use of COG threads. These threads are made of a dissolving material called PLA which remains for 1.5-2 years. This thread lifting is done under local anaesthesia and needs only 2-3 days of recovery time.

For advanced sagging of the face in older people, we have to do a surgery called facelift and neck lift. This gives a very good improvement in facial appearance and makes a person look 15-20 years younger. Though surgical procedures have a downtime of 3-4 weeks for recovery, the result lasts for many years.

Wrinkles are caused by the action of specific muscles. These can be eliminated by injection of botulinum toxin ( Botox) in specific areas. It keeps you looking fresh and young much longer. It can also prevent or push back a facelift for decadesespecially when combined with a good sunscreen and skincare regimen. This remains effective for 6-8 months and then needs to be repeated. These injections are very safe and give a good anti-ageing effect due to the loss of wrinkles.

The latest advances in anti-ageing are Nano-fat injections and PRP. PRP Microneedling along with PRP rejuvenation. The treatment increases your natural collagen which helps firm the skin, fine lines, and sun damage. It has been a game-changer for my patients in their 40s that desire a long-term investment into their skin health. Our own fat and blood have a lot of regenerative cells. In Nano-fat treatment, a small amount of our fat is removed using a tiny needle, it is processed and the concentrate is injected in specific areas of the face to improve wrinkles, sagging and under-eye dark circles. Similarly, our own blood can be processed to get Platelet-rich plasma ( PRP) and inject this into specific areas of the face for anti ageing effect.

Aptos Threads are a great treatment to rejuvenate skin. When placed superficially, the threads act as a support system for thin or sagging skin while promoting collagen production. The threads also can improve redness and brown spots. In addition, threads can be placed anywhere on the face, neck, or chest. In combination with deep threads, which lift without adding volume, it can make a huge difference for over 40 skin.

Fractionated CO2 Laser Skin Resurfacing is another one of the most popular anti-ageingtreatments. This treatment literally erases wrinkles. It helps to treat sun damage and collagen formation and gives you better-looking skin. It helps make the skin look younger after 40.

There are a lot of advanced laser treatments, face tightening machines such as HIFU (High-Intensity Focussed Ultrasound) and Ultherapy which also give a good effect on skin laxity. Ultherapy works best for the loose skin on the neck and jawline that is just starting to sag. Its an ultrasound treatment that tightens existing collagen and promotes the growth of new collagen. It has zero downtime.

Some patients repeat the treatment every one to two years to keep their skin firm and tight. Which treatment is suitable for a person can be checked by their cosmetic plastic surgeon and a customised treatment plan can be made for best results.

With inputs fromDr Parag Telang,Plastic & Reconstructive Surgeon

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Anti-aging treatments by experts for women in their 40's - India TV News

Junshi Biosciences and Coherus Announce PD-1 Inhibitor Toripalimab Granted Orphan Drug Designation for Small Cell Lung Cancer in the United States

SHANGHAI, China and REDWOOD CITY, Calif., April 14, 2022 (GLOBE NEWSWIRE) -- Shanghai Junshi Biosciences Co., Ltd. (“Junshi Biosciences”, HKEX: 1877; SSE: 688180) and Coherus BioSciences, Inc. (“Coherus”) announced today that the United States Food and Drug Administration ("FDA") has granted Orphan Drug Designation (“ODD”) for toripalimab, a PD-1 inhibitor, for the treatment of small cell lung cancer (“SCLC”). ODD is granted to drugs intended to treat rare diseases with a patient population less than 200,000 in the United States. The designation provides incentives to advance development and commercialization of drugs that have the potential to provide benefit to patients with rare diseases.

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Junshi Biosciences and Coherus Announce PD-1 Inhibitor Toripalimab Granted Orphan Drug Designation for Small Cell Lung Cancer in the United States

Agios Announces Publication of Phase 3 ACTIVATE Study in New England Journal of Medicine Demonstrating Benefits of PYRUKYND® (mitapivat) for Adults…

– In Adults with Pyruvate Kinase (PK) Deficiency Who Are Not Regularly Transfused, PYRUKYND® Significantly Increased Hemoglobin Level, Decreased Hemolysis and Improved Patient-Reported Outcomes –

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Agios Announces Publication of Phase 3 ACTIVATE Study in New England Journal of Medicine Demonstrating Benefits of PYRUKYND® (mitapivat) for Adults...

Longeveron to Present at Longevity Leaders World Congress; Latinos and Alzheimer’s Symposium; International Frailty and Sarcopenia Research…

April events to highlight Longeveron’s commitment to developing cell therapeutics for chronic aging related diseases. April events to highlight Longeveron’s commitment to developing cell therapeutics for chronic aging related diseases.

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Longeveron to Present at Longevity Leaders World Congress; Latinos and Alzheimer’s Symposium; International Frailty and Sarcopenia Research...

BeyondSpring Files 2021 Annual Report on Form 20-F

NEW YORK, April 14, 2022 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (the “Company” or “BeyondSpring”) (Nasdaq: BYSI), a clinical stage global biopharmaceutical company focused on developing innovative cancer therapies to improve clinical outcomes for patients who have high unmet medical needs, today announced that it has filed its annual report on Form 20-F for the fiscal year ended December 31, 2021 with the U.S. Securities and Exchange Commission (“SEC”) on April 14, 2022. The annual report on Form 20-F, which contains the Company’s audited consolidated financial statements, can be accessed on the SEC’s website at www.sec.gov and on the Company’s website at www.beyondspringpharma.com under “Financials & Filings” in the Investors section.

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BeyondSpring Files 2021 Annual Report on Form 20-F

Immunicum AB: Immunicum to Participate in the New Cancer Research Consortium Oncode-PACT

Immunicum AB (“Immunicum” publ; IMMU.ST), a biopharmaceutical company focused on therapies addressing tumor recurrence and hard-to-treat established tumors, today announced that the company will participate in the public-private partnership Oncode-PACT, which will be supported by the National Growth Fund, an initiative of the Dutch Ministry of Economic Affairs and Climate Policy and the Ministry of Finance.

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Immunicum AB: Immunicum to Participate in the New Cancer Research Consortium Oncode-PACT