Canine Stem Cell Therapy Market: Market Growth Factors, Applications, Regional Analysis, Key Players and Forecasts by 2026 – PRnews Leader

AllTheResearchs published a research report on the Canine Stem Cell Therapy market, which represents a study for the period from 2020 to 2026. The research provides a near look at the market scenario and dynamics impacting its growth. This report highlights the crucial developments along with other events happening in the market which are marking on the growth and opening doors for future growth in the coming years. Additionally, the report is built based on the macro- and micro-economic factors and historical data that can influence the growth.

The global Canine Stem Cell Therapy market was valued at US$ 118.5 Mn in 2018 and is expected to reach US$ 240.7 Mn in 2026, growing at a CAGR of 9.3% during the forecast period.

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Key Players:

The global Canine Stem Cell Therapy market has been comprehensively analyzed and the different companies that occupy a large percentage of the market share in the regions mentioned have been listed out in the report. Industry trends that are popular and are causing a resurgence in the market growth are identified. A strategic profile of the companies is also carried out to identify the various subsidiaries that they own in the different regions and who are responsible for daily operations in these regions.

The Key Players Covered in Canine Stem Cell Therapy Market Study are:

How Report will help you to make decisions for business:

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Canine Stem Cell Therapy Market Segmentation

Canine Stem Cell Therapy market is split by Type and by Application. For the period 2015-2026, the growth among segments provide accurate calculations and forecasts for sales by Type and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.

Market Segmentation by Type:

Market Segmentation by Applications:

COVID-19 Impact on Canine Stem Cell Therapy Market:

The outbreak of COVID-19 has brought along a global recession, which has impacted several industries. Along with this impact COVID Pandemic has also generated few new business opportunities for Canine Stem Cell Therapy Market. Overall competitive landscape and market dynamics of Canine Stem Cell Therapy has been disrupted due to this pandemic. All these disruptions and impacts has been analysed quantifiably in this report, which is backed by market trends, events and revenue shift analysis. COVID impact analysis also covers strategic adjustments for Tier 1, 2 and 3 players of Canine Stem Cell Therapy Market.

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Research objectives:

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AllTheResearch was formed with the aim of making market research a significant tool for managing breakthroughs in the industry. As a leading market research provider, the firm empowers its global clients with business-critical research solutions. The outcome of our study of numerous companies that rely on market research and consulting data for their decision-making made us realise, that its not just sheer data-points, but the right analysis that creates a difference.While some clients were unhappy with the inconsistencies and inaccuracies of data, others expressed concerns over the experience in dealing with the research-firm. Also, same-data-for-all-business roles was making research redundant. We identified these gaps and built AllTheResearch to raise the standards of research support.

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Canine Stem Cell Therapy Market: Market Growth Factors, Applications, Regional Analysis, Key Players and Forecasts by 2026 - PRnews Leader

What Are the Treatment Options When Lymphoma Returns? – SurvivorNet

Dr. Stephen Schuster Penn Medicine

Finally entering into remission after youve gone through several weeks or months worth of treatment for non-Hodgkin lymphoma can feel like a huge victory. Sometimes remissions are long lasting, but in a certain percentage of people, the cancer can eventually return. If your cancer does stage a comeback, your doctor will be ready with another round of treatment that oncologists call second-line therapy.

What tools do we have for the second line? Well, the standard right now is the high-dose chemotherapy with autologous stem cell rescue approach, Dr. Stephen Schuster, medical oncologist at Penn Medicine, tells SurvivorNet. An autologous stem cell transplant gives you an infusion of your own stem cells the preliminary cells that will eventually grow into new blood cells to replace the ones chemotherapy destroys. It allows your doctor to give you very high doses of chemo to treat your cancer.

In the late 1980s and 1990s, stem cell therapy worked pretty well in about one-third of people who received it. But as doctors improved upon the first-line treatment in the early 2000s by combining chemotherapy with the monoclonal antibody rituximab (Rituxan) into a drug cocktail called R-CHOP, stem cell therapy no longer worked as well in the second line. The hunt was on for a new way to treat relapsed non-Hodgkin lymphoma.

Fortunately, several new and improved cancer treatments have been introduced, and other novel therapies are under investigation. It took us from the 1970s to the late 90s to improve on the four drug combination CHOP, which is still the standard, adding rituximab to that, Dr. Schuster says. Today, not only have the treatments gotten better, but the pace of new drug development has sped up, he says. Several new immunotherapies have come out, just in the last few years.

One new therapeutic option if your cancer has returned is immunotherapy harnessing the power of your immune system to go after your cancer. [Immunotherapy is] frequently discussed in the popular scientific literature, Dr. Schuster says. Some of it sounds like science fiction. Its very cool stuff.

One group of immunotherapy drugs, collectively known as the monoclonal antibodies, use a protein called an antibody to home in on a target on the surface of cancer cells. Rituxan is one such drug.

A few new immunotherapy drugs have been approved for non-Hodgkin lymphoma in recent years:

Chimeric antigen receptor (CAR) T-cell therapy is one of the newest high-tech cancer treatments. During this therapy, your treatment team will take your own immune cells, called T cells, and genetically modify and multiply them in a lab so that they attach to proteins on the surface of your lymphoma cells and attack them.

These treatments each work in a slightly different way. And they can be effective for people whove tried and failed at two previous treatments.

Were coming up with the best approaches for people who were not successfully treated by first- or second-line approaches, Dr. Schuster says.There are currently two FDA-approved CAR T products for people with diffuse large B-cell lymphoma who have failed two prior lines of treatment.

Say youve tried three separate treatments and your cancer has come back again. It can be frustrating to face yet another round of treatment, but here again, innovation is your friend.

Soon, another therapy called bispecific antibodies or bispecific T-cell engagers (BiTEs),is likely to be added to the mix, says Dr. Schuster. Unlike monoclonal antibodies, which attach to only one target, bispecific antibodies bind to two targets at once. They essentially pull together your immune cells and cancer cells to help your immune system more effectively treat your cancer.

With so many non-Hodgkin lymphoma therapies available, theres a much better chance that your doctor will eventually find something that works for your cancer. If youve been through several rounds of treatment without success, you can always consider enrolling in a clinical trial of a new and as-yet unapproved drug that be more effective than anything youve already tried.

Learn more about SurvivorNet's rigorous medical review process.

Dr. Stephen Schuster is a medical oncologist and director of the Lymphoma Program at Penn Medicine. He is also theRobert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research. Read More

Dr. Stephen Schuster Penn Medicine

What tools do we have for the second line? Well, the standard right now is the high-dose chemotherapy with autologous stem cell rescue approach, Dr. Stephen Schuster, medical oncologist at Penn Medicine, tells SurvivorNet. An autologous stem cell transplant gives you an infusion of your own stem cells the preliminary cells that will eventually grow into new blood cells to replace the ones chemotherapy destroys. It allows your doctor to give you very high doses of chemo to treat your cancer.

Fortunately, several new and improved cancer treatments have been introduced, and other novel therapies are under investigation. It took us from the 1970s to the late 90s to improve on the four drug combination CHOP, which is still the standard, adding rituximab to that, Dr. Schuster says. Today, not only have the treatments gotten better, but the pace of new drug development has sped up, he says. Several new immunotherapies have come out, just in the last few years.

One new therapeutic option if your cancer has returned is immunotherapy harnessing the power of your immune system to go after your cancer. [Immunotherapy is] frequently discussed in the popular scientific literature, Dr. Schuster says. Some of it sounds like science fiction. Its very cool stuff.

One group of immunotherapy drugs, collectively known as the monoclonal antibodies, use a protein called an antibody to home in on a target on the surface of cancer cells. Rituxan is one such drug.

A few new immunotherapy drugs have been approved for non-Hodgkin lymphoma in recent years:

Chimeric antigen receptor (CAR) T-cell therapy is one of the newest high-tech cancer treatments. During this therapy, your treatment team will take your own immune cells, called T cells, and genetically modify and multiply them in a lab so that they attach to proteins on the surface of your lymphoma cells and attack them.

These treatments each work in a slightly different way. And they can be effective for people whove tried and failed at two previous treatments.

Were coming up with the best approaches for people who were not successfully treated by first- or second-line approaches, Dr. Schuster says.There are currently two FDA-approved CAR T products for people with diffuse large B-cell lymphoma who have failed two prior lines of treatment.

Say youve tried three separate treatments and your cancer has come back again. It can be frustrating to face yet another round of treatment, but here again, innovation is your friend.

Soon, another therapy called bispecific antibodies or bispecific T-cell engagers (BiTEs),is likely to be added to the mix, says Dr. Schuster. Unlike monoclonal antibodies, which attach to only one target, bispecific antibodies bind to two targets at once. They essentially pull together your immune cells and cancer cells to help your immune system more effectively treat your cancer.

With so many non-Hodgkin lymphoma therapies available, theres a much better chance that your doctor will eventually find something that works for your cancer. If youve been through several rounds of treatment without success, you can always consider enrolling in a clinical trial of a new and as-yet unapproved drug that be more effective than anything youve already tried.

Learn more about SurvivorNet's rigorous medical review process.

Dr. Stephen Schuster is a medical oncologist and director of the Lymphoma Program at Penn Medicine. He is also theRobert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research. Read More

Excerpt from:
What Are the Treatment Options When Lymphoma Returns? - SurvivorNet

Philadelphia Based Company Wants to Bring Back the Dead With Stem Cells – Gilmore Health News

Waking up the dead science fiction or a Halloween night horror movie? No, thats the goal of Bioquarks ReAnima project. The project aims to restore neuronal activity in brain dead people by combining several techniques: stem cell injection, nerve stimulation, and laser.

Stem Cells

Stem cells are increasingly becoming a serious treatment option for many nervous disorders: Alzheimers, Parkinsons, brain injuries, etc. So why not repair the brains of the dead to bring them back to life? This idea, worthy of a science fiction (or horror) film, is the crazy project of a company based in Philadelphia: Bioquark.

Read Also: Old Human Cells Successfully Rejuvenated Via Stem Cell Technology

This is not the first time that the company wants to participate in such an experiment. In 2016, the ReAnima study was launched in Bangalore, India, together with Himanshu Bansal, an orthopedic surgeon at Anupam Hospital. His plan was to combine several techniques to revive 20 brain dead people.

ReAnima consisted of injecting patients with mesenchymal stem cells and peptides that help regenerate brain cells; these peptides were to be supplied by Bioquark. In addition to these injections, transcranial laser stimulation and nerve stimulation were planned. This project was stopped by the Indian authorities in November last year, as revealed then by Science magazine.

But the company did not admit defeat. This time, according to the company, they are close to finding a new location for their clinical trials. Ira Pastor, CEO of Bioquark, told the Stat website that the company would announce the process in Latin America in the coming months.

Read Also: HGH Improves Memory In Stroke Victims Study Shows

If the experiment follows the same protocol as planned in India, it may involve 20 people. The clinical trial would again involve the injection of the patients stem cells, fat, blood Then a mixture of peptides would be injected into the spinal cord to stimulate the growth of new nerve cells. This compound, called BQ-A, was tested on animal models with head trauma. In addition, the nerves would be stimulated by nerve stimulation and 15 days of laser therapy to stimulate the neurons to make nerve connections. Researchers could then monitor the effects of this treatment using electroencephalograms.

But such a protocol raises many questions: How would a clinical trial be conducted on officially deceased people? If the person recovers some brain activity, in what state would he be? Will families be given false hope with a treatment that may take a long time?

Read Also: UC San Diego: Adult Brain Cells Revert to Younger State Following Injury, Study Shows

There is no indication that such a protocol will work. The company has not even tested the entire treatment on animal models! The mentioned treatments, such as injection of stem cells or transcranial stimulation, were tested in other situations, but not in cases of brain death. In an article published in 2016, neurologist Ariane Lewis and bioethicist Arthur Caplan stressed that the experiment had no scientific basis and that it gave families false and cruel hopes of a cure.

Experiment to raise the dead blocked in India

Response to a trial on reversal of Death by Neurologic Criteria

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Philadelphia Based Company Wants to Bring Back the Dead With Stem Cells - Gilmore Health News

Next Steps: What to Do When the First Non-Hodgkin Lymphoma Treatment You Try Doesnt Work – SurvivorNet

Dr. Jennifer Crombie Dana-Farber Cancer Institute

About 60%of people with non-Hodgkin lymphoma, and specifically people with the most common subtype, diffuse large B-cell lymphoma, who go on the combination drug treatment R-CHOPwill be cured. Yet that still means about 40% of people will finish this treatment, only to discover that they still have to worry about their cancer.

Fortunately, the bounty of new treatments that have come out in recent years have given hope to people who didnt respond the first time around. Dr. Jennifer Crombie, medical oncologist at Dana-Farber Cancer Center, says she has good news for worried patients. If they fall into that subgroup of patients who dont have the response that were hoping for, or if their disease comes back after an initial remission, we do have other treatments, she tells SurvivorNet.

The typical next step if your cancer comes back or doesnt respond to R-CHOP is to get a different kind of chemotherapy than you had the first time. This is often called salvage chemotherapy. Each chemotherapy drug works a little bit differently for every person, and its possible that a new medicine will be more effective against your cancer.

Doctors follow up that second round of chemo with a stem cell transplant. These are patients own stem cells that we take from them and then give them back after additional chemotherapy, Dr. Crombie says.

Stem cells are the immature blood cells in your bone marrow. Some of them grow into the white blood cells that help your body fight infections. In non-Hodgkin lymphoma, those cells are abnormal. A transplant replaces the abnormal stem cells with healthy ones.

First, youll get high doses of chemotherapy to get rid of the damaged white blood cells. Then you get new, healthy stem cells either from yourself or a donor to repopulate your bone marrow. After a couple of weeks, the stem cells will start to make healthy new blood cells.

Because chemotherapy is part of the stem cell transplant, this treatment works best if your cancer is sensitive to chemotherapy. So you probably wont get a stem cell transplant unless your cancer is still sensitive to chemotherapy, Dr. Crombie says. But if you are responsive to chemotherapy, adding the stem cell transplant could put you into a lasting remission, or even cure your lymphoma.

What happens if a stem cell transplant doesnt keep your cancer at bay, or your cancer isnt sensitive to the salvage chemotherapy?

If the stem cell transplant doesnt put you into remission, your cancer comes back afterward, or your cancer doesnt respond to salvage chemotherapy, there is a new treatment that Dr. Crombie refers to as a breakthrough. Its called chimeric antigen receptor (CAR) T-cell therapy.

That is a novel therapy where a patients own immune cells, called T-cells, can be taken from the body and engineered in the lab, she says. Its sometimes referred to as a living therapy, because it uses actual living cells.

T-cells are the immune cells that help your body fight off germs. During this treatment, your doctor first separates out the T-cells from a sample of your blood. Those cells are then altered in a lab to make them produce special proteins chimeric antigen receptors on their surface. Then theyre multiplied, and millions of these cells go back into your body. Once there, the new fighter T-cells attach to a protein on the surface of cancer cells, and attack the cancer.

CAR T-cell therapy is also an exciting option for patients who havent been able to respond to chemotherapy before, or have had their disease come back despite prior therapy, Dr. Crombie says.

Now, researchers are investigating whether giving patients CAR-T cells earlier in treatment might keep their cancer away better than chemotherapy and stem cell transplant. The answer to that question is still unknown. Well have to await the data to see which is the better second choice in the future, Dr. Crombie tells SurvivorNet. Researchers are also studying the effectiveness of CAR-T cell therapy in other types of less aggressive non-Hodgkin lymphoma.

Learn more about SurvivorNet's rigorous medical review process.

Dr. Jennifer Crombie is a medical oncologist at Dana-Farber Cancer Institute in Boston, Massachusetts. She is also aninstructor in medicine at Harvard Medical School. Read More

Dr. Jennifer Crombie Dana-Farber Cancer Institute

Fortunately, the bounty of new treatments that have come out in recent years have given hope to people who didnt respond the first time around. Dr. Jennifer Crombie, medical oncologist at Dana-Farber Cancer Center, says she has good news for worried patients. If they fall into that subgroup of patients who dont have the response that were hoping for, or if their disease comes back after an initial remission, we do have other treatments, she tells SurvivorNet.

Doctors follow up that second round of chemo with a stem cell transplant. These are patients own stem cells that we take from them and then give them back after additional chemotherapy, Dr. Crombie says.

Stem cells are the immature blood cells in your bone marrow. Some of them grow into the white blood cells that help your body fight infections. In non-Hodgkin lymphoma, those cells are abnormal. A transplant replaces the abnormal stem cells with healthy ones.

First, youll get high doses of chemotherapy to get rid of the damaged white blood cells. Then you get new, healthy stem cells either from yourself or a donor to repopulate your bone marrow. After a couple of weeks, the stem cells will start to make healthy new blood cells.

Because chemotherapy is part of the stem cell transplant, this treatment works best if your cancer is sensitive to chemotherapy. So you probably wont get a stem cell transplant unless your cancer is still sensitive to chemotherapy, Dr. Crombie says. But if you are responsive to chemotherapy, adding the stem cell transplant could put you into a lasting remission, or even cure your lymphoma.

What happens if a stem cell transplant doesnt keep your cancer at bay, or your cancer isnt sensitive to the salvage chemotherapy?

If the stem cell transplant doesnt put you into remission, your cancer comes back afterward, or your cancer doesnt respond to salvage chemotherapy, there is a new treatment that Dr. Crombie refers to as a breakthrough. Its called chimeric antigen receptor (CAR) T-cell therapy.

That is a novel therapy where a patients own immune cells, called T-cells, can be taken from the body and engineered in the lab, she says. Its sometimes referred to as a living therapy, because it uses actual living cells.

T-cells are the immune cells that help your body fight off germs. During this treatment, your doctor first separates out the T-cells from a sample of your blood. Those cells are then altered in a lab to make them produce special proteins chimeric antigen receptors on their surface. Then theyre multiplied, and millions of these cells go back into your body. Once there, the new fighter T-cells attach to a protein on the surface of cancer cells, and attack the cancer.

CAR T-cell therapy is also an exciting option for patients who havent been able to respond to chemotherapy before, or have had their disease come back despite prior therapy, Dr. Crombie says.

Now, researchers are investigating whether giving patients CAR-T cells earlier in treatment might keep their cancer away better than chemotherapy and stem cell transplant. The answer to that question is still unknown. Well have to await the data to see which is the better second choice in the future, Dr. Crombie tells SurvivorNet. Researchers are also studying the effectiveness of CAR-T cell therapy in other types of less aggressive non-Hodgkin lymphoma.

Learn more about SurvivorNet's rigorous medical review process.

Dr. Jennifer Crombie is a medical oncologist at Dana-Farber Cancer Institute in Boston, Massachusetts. She is also aninstructor in medicine at Harvard Medical School. Read More

See more here:
Next Steps: What to Do When the First Non-Hodgkin Lymphoma Treatment You Try Doesnt Work - SurvivorNet

Stem Cell Therapy Market | Growth Strategies Adopted By Top Key Players,Future Trends ,Application Worldwide And Assessment To 2026 – PRnews Leader

Complete study of the global Stem Cell Therapy market is carried out by the analysts in this report, taking into consideration key factors like drivers, challenges, recent trends, opportunities, advancements, and competitive landscape. This report offers a clear understanding of the present as well as future scenario of the global Stem Cell Therapy industry. Research techniques like PESTLE and Porters Five Forces analysis have been deployed by the researchers. They have also provided accurate data on Stem Cell Therapy production, capacity, price, cost, margin, and revenue to help the players gain a clear understanding into the overall existing and future market situation.

The global Stem Cell Therapy market report reveals pertinent data on segment performance, growth potential in the coming years as well as vendor and manufacturer activities, aligning appropriately with consumption and production developments.

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The pandemic of Coronavirus (COVID-19) has affected every aspect of life worldwide. This has brought along several changes in market conditions. The rapidly changing industry scenario and initial and future assessment of the impact are covered in the report. The Stem Cell Therapy market report puts together a concise analysis of the growth factors influencing the current business scenario across various regions. Significant information pertaining to the industry analysis size, share, application, and statistics are summed in the report in order to present an ensemble prediction.

Some of the key reader queries that have been adequately addressed in the report include, top vendors and their growth triggering business strategies, regional outlook and growth hotspot identification, followed by prominent growth retardants, challenges and threat probability which result in dwarfed growth outlook. Further, to instill new market participation amongst novel enthusiast, this report clearly focuses teeming business opportunities that ensure smooth rise despite odds and growing competition.

Browse the complete report Along with TOC @ https://www.adroitmarketresearch.com/industry-reports/stem-cell-therapy-market

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Stem Cell Therapy industry. In order to fulfill the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Stem Cell Therapy Market Segmentation

Type Analysis of Stem Cell Therapy Market:

Based on cell source, the market has been segmented into,

Adipose Tissue-Derived Mesenchymal SCs Bone Marrow-Derived Mesenchymal SCs Embryonic SCs Other Sources

Applications Analysis of Stem Cell Therapy Market:

Based on therapeutic application, the market has been segmented into,

Musculoskeletal Disorders Wounds & Injuries Cardiovascular Diseases Gastrointestinal Diseases Immune System Diseases Other Applications

Key questions answered in the report:

1. What is the growth potential of the Stem Cell Therapy market? 2. Which product segment will grab a lions share? 3. Which regional market will emerge as a frontrunner in coming years? 4. Which application segment will grow at a robust rate? 5. What are the growth opportunities that may emerge in Stem Cell Therapy industry in the years to come? 6. What are the key challenges that the global Stem Cell Therapy market may face in future? 7. Which are the leading companies in the global Stem Cell Therapy market? 8. Which are the key trends positively impacting the market growth? 9. Which are the growth strategies considered by the players to sustain hold in the global Stem Cell Therapy market?

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Stem Cell Therapy Market | Growth Strategies Adopted By Top Key Players,Future Trends ,Application Worldwide And Assessment To 2026 - PRnews Leader

Here’s What Happens When Lab-Grown Mini-Lungs Are Exposed to SARS-CoV-2 – ScienceAlert

Scientists working on a lab-grown mini-lung are now using their living model to better understand the current pandemic and potential new treatments.

The most recent version of this unique organoid is based entirely on human stem cells, known to repair the deepest parts of our lungs. When the researchers exposed it to SARS-CoV-2, the results were illuminating.

Dropping just one of these self-renewing units into a dish containing a tailored growth solution can produce millions of cells in a clump that resembles the tiny air sacs in human lungs.

Known as alveoli, these balloon-like sacs have shown diffuse damage in fatal cases of COVID-19, and while this havoc is often attributed to a storm of immune cells called cytokines, we're still figuring out how lung injury actually comes about.

The new mini-model gives us a glimpse of the battle on a molecular scale, and while it's nowhere near as complex as a real human lung, that's also what makes it easier to control and observe.

The unique organoid includes just one type of lung stem cell, known as an alveolar type 2 epithelial cell (AT2), which has the ability to self-renew, differentiate into other lung cells, keep the sac open with surfactants, and directly bind to viruses.

When the SARS-CoV-2 virus was introduced into this organoid's dish, researchers say the virus quickly infected the AT2 cells and spread throughout the alveoli-like structure.

The infection also triggered an inflammatory response in the organoid, reducing the production and proliferation of surfactant and inducing cell death, sometimes in surrounding areas that hadn't even yet been touched by the virus.

"This is a major breakthrough for the field because we were using cells that didn't have purified cultures," explains Ralph Baric, an epidemiologist, microbiologist, and immunologist at the University of North Carolina.

"This is incredibly elegant work to figure out how to purify and grow AT2 cells in culture."

Analysing the gene expression of these mini-organs, researchers found the inflammatory state triggered by the SARS-CoV-2 infection led to the production of interferons, cytokines, chemokines, and activation of genes related to cell death.

What's more, these signatures showed "striking similarity" to what's seen in severe COVID-19 patients.The results also match recent growing evidence that suggests severe cases of COVID-19 trigger a cytokine storm that may leave the lungs susceptible to damage.

Most of these observations, however, come from autopsies and have not been observed in living tissue.

This newly-developed model is a unique and versatile new way to study respiratory viruses in action, and it shows how a cascade of defences within stem cells themselves may cause more damage than good.

"It was thought cytokine storm happened due to the large influx of immune cells, but we can see it also happens in the lung stem cells themselves," says cell biologist Purushothama Rao Tata from Duke University.

"Now we have a way to figure out how to energise the cells to fight against this deadly virus," he adds.

In another set of experiments on the mini-lung, researchers found that administering low doses of interferons before infection slowed the spread of the virus, whereas reducing interferons before infection worsened the damage.

This suggests interferons are somehow mediating the immune response in our alveoli, slowing the cascade of cell death as the lung tries to get ahead of the infection.

But this may not be the whole picture; it's just a small insight into what's going on.Other recent studies show that while interferons might be a helpful treatment at certain stages of infection, at other times they can make matters worse.

While there are still many kinks and details that need to be ironed out in their model, researchers hope they can one day grow mini-lungs on which hundreds of experiments can be run at the same time, allowing us to figure out how the lung responds to infection and also how we can best protect it.

There's never been a more important time to learn more.

The study was published in Cell Stem Cell.

The rest is here:
Here's What Happens When Lab-Grown Mini-Lungs Are Exposed to SARS-CoV-2 - ScienceAlert

Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant…

This article was originally published here

Br J Haematol. 2020 Oct 29. doi: 10.1111/bjh.17131. Online ahead of print.

ABSTRACT

Although new multiple myeloma (MM) therapies are effective in alleviating some disease-associated symptoms (e.g. bone pain, fatigue, functional decline), they can result in additional toxicities, further impacting health-related quality of life (HRQoL). Here, we compared HRQoL and safety of lenalidomide-bortezomib-dexamethasone [RVd (n = 445)], bortezomib-melphalan-prednisone [VMP (n = 77)] and Vd or VMP (n = 588) in patients with newly diagnosed MM (NDMM) from the Connect MM Registry, a large, USA, multicentre, prospective observational cohort study. Functional Assessment of Cancer Therapy-Multiple Myeloma subscale, EuroQol-5D overall score and Bone Pain Inventory HRQoL scores were significantly improved with RVd versus Vd/VMP. Serious adverse event rates were similar in all groups. Treatment with RVd maintained HRQoL in this real-world, largely community-based population of patients with NDMM.

PMID:33118614 | DOI:10.1111/bjh.17131

Link:
Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant...

Stem Cell Therapy Market: Applications and Regional Insights During the Forecasted Period 2020-2030 – PRnews Leader

Prophecy Market Insights has recently published the Stem Cell Therapy informational report which evaluates market size, growth rate, profit margin, raw material availability, impact strength, competition, technology, and environmental and legal factors.

The report covers all recent trends, opportunities, drivers, and restraints of the Stem Cell Therapy market coupled with their impact on demand over the forecast period. Additionally, the report provides a comprehensive view of the market by offering exhaustive value chain analysis. It provides in-depth information about value addition at each stage of the value chain.

Comprehensive information pertaining to fire alarm systems and its properties is provided in this section. This section also highlights the inclusions and exclusions, which help readers to understand the scope of the market report.

This segment includes factors that have emerged as key successful factors and strategies adopted by key market participants.

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The Stem Cell Therapy market report provides a detailed analysis of market players according to its production footprint, market share, and growth rate. The report also covers SWOT analysis (strengths, weaknesses, opportunities, and threats) of the players. Besides, the Stem Cell Therapy market study depicts the recent launches, R&D projects, agreements, and business strategies of the market players including market segmentation and regional analysis of the market.

The Stem Cell Therapy market study covers both the top-down and bottom-up approaches that have been used to calculate and authenticate the market size and estimate the scenario of various sub-markets in the global market. The report estimation size of the market both in terms of volume (x units) and value (Mn/Bn USD).

Stem Cell Therapy Market by Top Manufacturers:

Scope of the Market Research Report:

The report takes into account the impact of the novel COVID-19 pandemic on the market and provides a clear assessment of the estimated market fluctuations throughout the forecast period.

Important Questions Answered in Stem Cell Therapy Market Report:

Segmentation Overview:

Global Stem Cell Therapy Market, By Treatment Type:

Global Stem Cell Therapy Market, By Cell Source:

Global Stem Cell Therapy Market, By Indication:

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Stem Cell Therapy Market: Applications and Regional Insights During the Forecasted Period 2020-2030 - PRnews Leader

Innovations in the Rheumatoid Arthritis Stem Cell Therapy Field Likely to Aid the Growth of the Rheumatoid Arthritis Stem Cell Therapy Market 2018 to…

Fact.MR has recently published a report, titled [Global Rheumatoid Arthritis Stem Cell Therapy Market 2020 by Key Countries, Companies, Type and Application]. The research report provides an in-depth explanation of the various factors that are likely to drive the market. It discusses the future of the market by studying the historical details. Analysts have studied the ever-changing market dynamics to evaluate their impact on the overall market. In addition, the report also discusses the segments present in the market. Primary and secondary research methodologies have been used to provide the readers with an accurate and precise understanding of the overall The Rheumatoid Arthritis Stem Cell Therapy market. Analysts have also given readers an unbiased opinion about the direction companies will take during the forecast period.

The research report also includes the global market figures that provide historical data as well as estimated figures. It gives a clear picture of the growth rate of the market during the forecast period. The report aims to give the readers quantifiable data that is collected from verified data. The report attempts to answer all the difficult questions such as market sizes and company strategies.

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Competitive landscape

Global Rheumatoid Arthritis Stem Cell Therapy Market: Drivers and Restraints

The report explains the drivers shaping the future of the Rheumatoid Arthritis Stem Cell Therapy market. It evaluates the various forces that are expected to create a positive influence on the overall market. Analysts have studied the investments in research and development of products and technologies that are expected to give the players a definite boost. Furthermore, researchers have also included an analysis of the changing consumer behavior that is projected to impact the supply and demand cycles present in the global The Rheumatoid Arthritis Stem Cell Therapy market. Evolving per capita earnings, improving economic statuses, and emerging trends have all been studied in this research report.

The research report also explains the potential restraints present in the global The Rheumatoid Arthritis Stem Cell Therapy market. It evaluates the aspects that are likely to hamper the market growth in the near future. In addition to this assessment, it also provides a list of opportunities that could prove lucrative to the overall market. Analysts provide solutions for turning threats and restraints into successful opportunities in the coming years.

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Global Rheumatoid Arthritis Stem Cell Therapy Market: Regional Segmentation

In the successive chapters, analysts have studied the regional segments present in the global The Rheumatoid Arthritis Stem Cell Therapy market. This gives the readers a narrowed-view of the global market enabling a closer look at the elements that could define its progress. It highlights myriad regional aspects such as the impact of culture, environment, and government policies that influence the regional markets.

Global Rheumatoid Arthritis Stem Cell Therapy Market: Competitive Landscape

The last chapter of the global The Rheumatoid Arthritis Stem Cell Therapy market research report focuses solely on the competitive landscape. It studies the key players present in the market. In addition to a brief overview of the company, analysts shed light on their valuation and evolution. It also mentions the list of important products and the ones in the pipeline. The competitive landscape is analyzed by understanding the strategies of the companies and the initiatives they have taken in recent years to overcome the intensive competition.

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Innovations in the Rheumatoid Arthritis Stem Cell Therapy Field Likely to Aid the Growth of the Rheumatoid Arthritis Stem Cell Therapy Market 2018 to...

Stem Cell Umbilical Cord Blood Market to Enable the Stakeholders to Capitalize on the Prevailing Industry Opportunities with Investment Analysis By…

marketresearchhub Presents Stem Cell Umbilical Cord Blood Market Size, Status and Forecast 2020-2026 New Document to its Studies Database

This report, which has been published, is having a meaningful Stem Cell Umbilical Cord Blood market insight. It casts some lights on industry products and services. Along with those product applications, it also examined whether it reaches up to the end-users or not. This report on this Stem Cell Umbilical Cord Blood market has given an overall view of the recent technologies used and technological improvements. It also focuses on recent industry trends and which products are quite demanding from a customers perspective. This report is focused on every aspect of the forecast year 2026.

Stem Cell Umbilical Cord Blood Market dynamics analysis

This report is representing a whole market scenario on a global basis. In this report, we can also find the analysis growth of industries. Through this report, we can easily interpreter the level of market competition, different pricing models, the latest market trends, customer demand, etc. This report acknowledges the revenue model and market expansion of this Stem Cell Umbilical Cord Blood market. If you want to get that full market information, then this report can help you. It also gives a comprehensive knowledge about the demand and supply graph. Suppose that demand curves moved downward, then from this report, you can know about those factors responsible for its decline. Accordingly, you can know the responsible factors for the rising curve. This Stem Cell Umbilical Cord Blood market report gives a total knowledge about the market trend and improves its strategies and pricing model.

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In the competitive analysis section of the report, leading as well as prominent players of the global Stem Cell Therapy for Osteoarthritis market are broadly studied on the basis of key factors. The report offers comprehensive analysis and accurate statistics on revenue by the player for the period 2015-2020. It also offers detailed analysis supported by reliable statistics on price and revenue (global level) by player for the period 2015-2020. The key players covered in this study Mesoblast Regeneus U.S. Stem Cell Anterogen Asterias Biotherapeutics

Research and Methodology

For the research, the Stem Cell Umbilical Cord Blood markets research teams are adopted various high-end techniques. Industry best analysts are worked on this report. They collected data from various reliable sources and have taken samples of different market segments. They utilize both qualitative and quantitative data in this report. All data are based on primary sources, which are focused on the assessment year 2020-2026. For wise decision-making, they have also done SWOT analysis, which can also help them know their predicted future results. This report also helps to develop Stem Cell Umbilical Cord Blood market growth by improvising its strategic models.

segment by Type, the product can be split into Monotherapy Combination Therapy

Market segment by Application, split into Osteoarthritis (unspecified) Knee Osteoarthritis Shoulder Osteoarthritis Hip Osteoarthritis

Based on regional and country-level analysis, the Stem Cell Therapy for Osteoarthritis market has been segmented as follows: North America United States Canada Europe Germany France U.K. Italy Russia Nordic Rest of Europe Asia-Pacific China Japan South Korea Southeast Asia India Australia Rest of Asia-Pacific Latin America Mexico Brazil Middle East & Africa Turkey Saudi Arabia UAE Rest of Middle East & Africa

Regional and Country-level Analysis

The Stem Cell Umbilical Cord Blood market is analysed and market size information is provided by regions (countries).

The key regions covered in the Stem Cell Umbilical Cord Blood market report are North America, Europe, Asia Pacific, Latin America, Middle East and Africa. It also covers key regions (countries), viz, U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, India, Australia, Taiwan, Indonesia, Thailand, Malaysia, Philippines, Vietnam, Mexico, Brazil, Turkey, Saudi Arabia, U.A.E, etc.

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Table Of Content Covered In this Stem Cell Umbilical Cord Blood Market Report:

1 Report Overview

2 Global Growth Trends by Regions

3 Competition Landscape by Key Players

4 Breakdown Data by Type (2015-2026)

5 Breakdown Data by Application (2015-2026)

6 North America

7 Europe

8 China

9 Japan

10 Southeast Asia

11 India

12 Central & South America

13Key Players Profiles

14Analysts Viewpoints/Conclusions

NOTE : Our team is studying Covid-19 and its impact on various industry verticals and wherever required we will be considering Covid-19 footprints for a better analysis of markets and industries. Cordially get in touch for more details

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Stem Cell Umbilical Cord Blood Market to Enable the Stakeholders to Capitalize on the Prevailing Industry Opportunities with Investment Analysis By...