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Researchers find that fish oil may help with depression – Jill Lopez

By Adult Stem Cells

A study published inMolecular Psychiatryshows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

Using stem cells from adults with a clinical diagnosis of depression, theUniversity of Illinois at Chicagoresearchers who conducted the study also found that fish oil, when tested in the model, created an antidepressant response.

UIC's Mark Rasenick, principal investigator of the study, says that the research provides a number of novel findings that can help scientists better understand how the brain works and why some people respond to drug treatment for depression, while others experience limited benefits from antidepressant medication.

"It was also exciting to find scientific evidence that fish oil -- an easy-to-get, natural product -- may be an effective treatment for depression," said Rasenick, UIC distinguished professor of physiology and biophysics and psychiatry at the College of Medicine.

Major depressive disorder, or depression, is the most common psychiatric disorder. Around one in six individuals will experience at least one depressive episode in their lifetime. However, antidepressant treatment fails in about one-third of patients.

In the study, the UIC researchers used skin cells from adults with depression that were converted into stem cells at Massachusetts General Hospital and then directed those stem cells to develop into nerve cells. The skin biopsies were taken from two types of patients: people who previously responded to antidepressant treatment and people who have previously been resistant to antidepressants.

When fish oil was tested, the models from treatment-sensitive and treatment-resistant patients both responded.

Rasenick says the response was similar to that seen from prescription antidepressants, but it was produced through a different mechanism.

"We saw that fish oil was acting, in part, on glial cells, not neurons," said Rasenick, who is also a research career scientist at Jesse Brown VA Medical Center and president and chief scientific officer at Pax Neuroscience, a UIC startup company. "For many years, scientists have paid scant attention to glia -- a type of brain cell that surrounds neurons -- but there is increasing evidence that glia may play a role in depression. Our study suggests that glia may also be important for antidepressant action.

"Our study also showed that a stem cell model can be used to study response to treatment and that fish oil as a treatment, or companion to treatment, for depression warrants further investigation," Rasenick said.

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Researchers find that fish oil may help with depression - Jill Lopez

Adipose Tissue-derived Stem Cell Therapy Market Share Analysis, Application, Strategies of Key Players & Forecast to 2025 – Daily Research…

By Stem Cell Treatment

The Global Adipose Tissue-derived Stem Cell Therapy Market report offers users the detailed study of the market and its main aspects. The study on Global Adipose Tissue-derived Stem Cell Therapy Market, offers profound understandings about the Adipose Tissue-derived Stem Cell Therapy Market covering all the essential aspects of the market. The report provides competitive pipeline landscape of the Global Factors like production, market share, revenue rate, regions and key players define a market study start to end. This report gives an overview of market valued in the year 2019 and its growth in the coming years till 2025.

This study covers following key players: The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report: Breakdown data in in Chapter 3. AlloCure Tissue Genesis Antria Cellleris Corestem Celgene Corporation Mesoblast Cytori Therapeutics Pluristem Therapeutics Intrexon Lonza BioRestorative Therapies Pluristem Therapeutics iXCells Biotechnologies Cyagen Celltex Therapeutics Corporation

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The study is done with the help of analysis such as SWOT analysis and PESTEL analysis. It consists of the detailed study of current market trends along with the past statistics. The past years are considered as reference to get the predicted data for the forecast period. The report covers complete analysis of the Adipose Tissue-derived Stem Cell Therapy Market on the basis of regional and Global level. Various important factors such as market trends, revenue growth patterns market shares and demand and supply are included in almost all the market research report for every industry.

There are different marketing strategies that every marketer looks up to in order to ace the competition in the Global market. Some of the primary marketing strategies that is needed for every business to be successful are Passion, Focus, Watching the Data, Communicating the value To Your Customers, Your Understanding of Your Target Market. There is a target set in market that every marketing strategy has to reach. In addition, it also covers political and social factors which is likely to affect the growth of the market. It also covers and analysis several segments which are present in the market. A significant development has been recorded by the market of Adipose Tissue-derived Stem Cell Therapy, in past few years. It is also for it to grow further. Various important factors such as market trends, revenue growth patterns market shares and demand and supply are included in almost all the market research report for every industry.

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Market segment by Type, the product can be split into Segmentation by type: breakdown data from 2015 to 2020 in Section 2.3; and forecast to 2025 in section 10.7. Autologous Stem Cells Allogeneic Stem Cells

Segmentation by application: breakdown data from 2015 to 2020, in Section 2.4; and forecast to 2025 in section 10.8. Therapeutic Application Research Application

This report also splits the market by region: Breakdown data in Chapter 4, 5, 6, 7 and 8. Americas United States Canada Mexico Brazil APAC China Japan Korea Southeast Asia India Australia Europe Germany France UK Italy Russia Middle East & Africa Egypt South Africa Israel Turkey GCC Countries

The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report: Breakdown data in in Chapter 3. AlloCure Tissue Genesis Antria Cellleris Corestem Celgene Corporation Mesoblast Cytori Therapeutics Pluristem Therapeutics Intrexon Lonza BioRestorative Therapies Pluristem Therapeutics iXCells Biotechnologies Cyagen Celltex Therapeutics Corporation

Market segment by Application, split into Segmentation by application: breakdown data from 2015 to 2020, in Section 2.4; and forecast to 2025 in section 10.8. Therapeutic Application Research Application

One of the ways for the estimation for the growth of the market is estimation of the market share by the regions which is likely to contribute to the growth of the market in the estimated forecast period. In this, the growth and fall of each region is covered which is likely to boost the growth of the Adipose Tissue-derived Stem Cell Therapy Market. In addition, to determine and use precise methods, research methodology such as the qualitative and quantitative data is used for the estimation and determination of the Global Adipose Tissue-derived Stem Cell Therapy Market.

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Adipose Tissue-derived Stem Cell Therapy Market Share Analysis, Application, Strategies of Key Players & Forecast to 2025 - Daily Research...

Induced Pluripotent Stem Cells Market Outlook With Key Player, Regions, CAGR of 12.2%, and Specification, Cost Analysis, Price and Gross Margin by…

By Adult Stem Cells

Final Report will add the analysis of the impact of COVID-19 on this industry.

Global Induced Pluripotent Stem Cells Market Research Report 2015-2026 is a historical overview and in-depth study on the current & future market of the Induced Pluripotent Stem Cells industry. The report represents a basic overview of the Induced Pluripotent Stem Cells market share, status, competitor segment with a basic introduction of key vendors, top regions, product types and end industries. This report gives a historical overview of the Induced Pluripotent Stem Cells market trends, growth, revenue, capacity, cost structure, and key drivers analysis.

Request a sample copy of the report https://www.industryresearch.biz/enquiry/request-sample/15898863

The report offers detailed coverage of the Global Induced Pluripotent Stem Cells market which includes industry chain structure, definitions, applications, and classifications. The global Induced Pluripotent Stem Cells market analysis is provided for the international markets including development trends, competitive landscape analysis, investment plan, business strategy, opportunity, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, industry share, policy, price, revenue and gross margins.

Pluripotent stem cells are embryonic stem cells that have the potential to form all adult cell types and help in repairing of damaged tissues in the human body. An induced pluripotent stem cells, or iPSCs, are taken from any tissue (usually skin or blood) from a child or an adult and is genetically modified to behave like pluripotent stem cells or embryonic stem cells.

iPSCs market is in emerging state mainly due to its ability to make any cell or tissue the body might need to encounter wide range of diseases like diabetes, spinal cord injury, leukaemia or heart disease, these cells can potentially be customized to provide a perfect genetic match for any patient.

Market Analysis and Insights: Global Induced Pluripotent Stem Cells Market

The global Induced Pluripotent Stem Cells market size is projected to reach US$ 92 million by 2026, from US$ 82 million in 2020, at a CAGR of 12.2%% during 2021-2026.

Global Induced Pluripotent Stem Cells Scope and Market Size

Induced Pluripotent Stem Cells market is segmented by Type, and by Application. Players, stakeholders, and other participants in the global Induced Pluripotent Stem Cells market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2015-2026.

Enquire before purchasing this report https://www.industryresearch.biz/enquiry/pre-order-enquiry/15898863

Report Scope And Segmentation Table:

Types:

Hepatocytes, Fibroblasts, Keratinocytes, Amniotic Cells, Others,

Applications:

Academic Research, Drug Development And Discovery, Toxicity Screening, Regenerative Medicine,

Key Players:

Fujifilm Holding Corporation, Astellas Pharma, Fate Therapeutics, Bristol-Myers Squibb Company, ViaCyte, Celgene Corporation, Aastrom Biosciences, Acelity Holdings, StemCells, Japan Tissue Engineering, Organogenesis,

CAGR 2021-2026:

12.2%

Market Size 2020:

USD 82 million

Market Size 2026:

USD 92 million

Historical Years:

2015-2019

Base Year:

2019

With tables and figures helping analyze worldwide Global Induced Pluripotent Stem Cells market growth, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

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Induced Pluripotent Stem Cells Market Report Contains Following Points in TOC:

Chapter 1: Induced Pluripotent Stem Cells Market Product Overview, Market Segment, Size, Sales, Growth Rate, Price by Type

Chapter 2: Global Induced Pluripotent Stem Cells Market Competition, Sales, Price, Base Distribution, Sales Area, Product Types, and Trends by Company

Chapter 3: Induced Pluripotent Stem Cells Company Basic Information, Manufacturing Base and Competitors, Product Category, Applications and Specifications, Price and Gross Margin (2015-2026)

Chapter 4: Induced Pluripotent Stem Cells Market Status, Size, CAGR, Revenue, Price, Gross Margin and Outlook by Regions

Chapter 5: Induced Pluripotent Stem Cells Market Sales, and Share Segment by Application/End Users

Chapter 6: Global Induced Pluripotent Stem Cells Market Sales, Revenue, Growth Rate Forecast (2021-2026)

Chapter 7: Induced Pluripotent Stem Cells Upstream Raw Materials, Price, Key Suppliers, Cost Structure, Manufacturing Expenses, Industrial Chain Analysis

Chapter 8: Marketing Strategy Analysis, Distributors

Chapter 9: Research Findings and Conclusion

Detailed TOC of Global Induced Pluripotent Stem Cells Market @ https://www.industryresearch.biz/TOC/15898863

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Induced Pluripotent Stem Cells Market Outlook With Key Player, Regions, CAGR of 12.2%, and Specification, Cost Analysis, Price and Gross Margin by...

Stem Cell Cartilage Regeneration Market 2020 Global Industry Size, Segments, Share and Growth Factor Analysis, Top Key Players Research Report 2026 |…

By Stell Cell Research

Global Stem Cell Cartilage Regeneration Market 2020 Industry Research Report is an inside-out and expert examination on the flow condition of the Global Stem Cell Cartilage Regeneration industry. In addition to that, this latest investigative report sorts the global Stem Cell Cartilage Regeneration market by end client, type, area, and top players/brands. This report further elaborates various factors affecting the market drivers and development. Stem Cell Cartilage Regeneration market also puts forward insights into market size, crucial markers, review, as well as the most recent net edge, income, types, patterns, along with provincial figure and examination.

Get a Sample PDF of report at https://www.researchreportsworld.com/enquiry/request-sample/15528414

The global Stem Cell Cartilage Regeneration market is anticipated to rise at a considerable rate during the forecast period, between 2020 and 2026. In 2020, the market was growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

The Global Stem Cell Cartilage Regeneration market 2020 research provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Global Stem Cell Cartilage Regeneration Market Share analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed.

Final Report will add the analysis of the impact of COVID-19 on this industry.

Under COVID-19 Outbreak, how the Stem Cell Cartilage Regeneration Industry will develop is also analyzed in detail in Chapter 1.7 of the report. In Chapter 2.4, we analyzed industry trends in the context of COVID-19 for Stem Cell Cartilage Regeneration Market. In Chapter 3.5, we analyzed the impact of COVID-19 on the product industry chain based on the upstream and downstream markets for Stem Cell Cartilage Regeneration Market. In Chapters 6 to 10 of the report, we analyze the impact of COVID-19 on various regions and major countries on Stem Cell Cartilage Regeneration Market. In chapter 13.5, the impact of COVID-19 on the future development of the industry is pointed out.

To Understand How COVID-19 Impact is Covered in This Report. Get Sample copy of the report at https://www.researchreportsworld.com/enquiry/request-covid19/15528414

The report can help to understand the market and strategize for business expansion accordingly. In the strategy analysis, it gives insights from marketing channel and market positioning to potential growth strategies, providing in-depth analysis for new entrants or exists competitors in the Stem Cell Cartilage Regeneration industry.This report also states import/export consumption, supply and demand Figures, cost, price, revenue and gross margins. For each manufacturer covered, this report analyzes their Stem Cell Cartilage Regeneration manufacturing sites, capacity, production, ex-factory price, revenue and market share in global market.

Global Stem Cell Cartilage Regeneration Market Report 2020 provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

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List Of TOP KEY PLAYERS in Stem Cell Cartilage Regeneration Market Report are

Get a Sample Copy of the Stem Cell Cartilage Regeneration Market Report 2020

The report also focuses on global major leading industry players of Global Stem Cell Cartilage Regeneration Market Share providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out. With tables and figures helping analyse worldwide Global Stem Cell Cartilage Regeneration Market Forecast this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

The Global Stem Cell Cartilage Regeneration Market Trends, development and marketing channels are analysed. Finally, the feasibility of new investment projects is assessed and overall research conclusions offered.

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On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into

On the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including

Some of the key questions answered in this report:

Major regions covered in the report:

Major Points from Table of Contents:

1 Report Overview 1.1 Study Scope 1.2 Key Market Segments 1.3 Regulatory Scenario by Region/Country 1.4 Market Investment Scenario Strategic 1.5 Market Analysis by Type 1.5.1 Global Stem Cell Cartilage Regeneration Market Share by Type (2020-2026) 1.5.2 Cell based approaches 1.5.3 Non-cell based approaches 1.6 Market by Application 1.6.1 Global Stem Cell Cartilage Regeneration Market Share by Application (2020-2026) 1.6.2 Hyaline cartilage 1.6.3 Fibrocartilage 1.6.4 Other 1.7 Stem Cell Cartilage Regeneration Industry Development Trends under COVID-19 Outbreak 1.7.1 Global COVID-19 Status Overview 1.7.2 Influence of COVID-19 Outbreak on Stem Cell Cartilage Regeneration Industry Development 2. Global Market Growth Trends 2.1 Industry Trends 2.1.1 SWOT Analysis 2.1.2 Porters Five Forces Analysis 2.2 Potential Market and Growth Potential Analysis 2.3 Industry News and Policies by Regions 2.3.1 Industry News 2.3.2 Industry Policies 2.4 Industry Trends Under COVID-19 3 Value Chain of Stem Cell Cartilage Regeneration Market 3.1 Value Chain Status 3.2 Stem Cell Cartilage Regeneration Manufacturing Cost Structure Analysis 3.2.1 Production Process Analysis 3.2.2 Manufacturing Cost Structure of Stem Cell Cartilage Regeneration 3.2.3 Labor Cost of Stem Cell Cartilage Regeneration 3.2.3.1 Labor Cost of Stem Cell Cartilage Regeneration Under COVID-19 3.3 Sales and Marketing Model Analysis 3.4 Downstream Major Customer Analysis (by Region) 3.5 Value Chain Status Under COVID-19 4 Players Profiles 4.1 BioTissue Technologies 4.1.1 BioTissue Technologies Basic Information 4.1.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.1.3 BioTissue Technologies Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.1.4 BioTissue Technologies Business Overview 4.2 Anika Therapeutics 4.2.1 Anika Therapeutics Basic Information 4.2.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.2.3 Anika Therapeutics Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.2.4 Anika Therapeutics Business Overview 4.3 Biomet 4.3.1 Biomet Basic Information 4.3.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.3.3 Biomet Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.3.4 Biomet Business Overview 4.4 Smith & Nephew 4.4.1 Smith & Nephew Basic Information 4.4.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.4.3 Smith & Nephew Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.4.4 Smith & Nephew Business Overview 4.5 EMD Serono 4.5.1 EMD Serono Basic Information 4.5.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.5.3 EMD Serono Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.5.4 EMD Serono Business Overview 4.6 Zimmer 4.6.1 Zimmer Basic Information 4.6.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.6.3 Zimmer Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.6.4 Zimmer Business Overview 4.7 CellGenix 4.7.1 CellGenix Basic Information 4.7.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.7.3 CellGenix Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.7.4 CellGenix Business Overview 4.8 Sanofi Aventis 4.8.1 Sanofi Aventis Basic Information 4.8.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.8.3 Sanofi Aventis Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.8.4 Sanofi Aventis Business Overview 4.9 DePuy (Johnson & Johnson) 4.9.1 DePuy (Johnson & Johnson) Basic Information 4.9.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.9.3 DePuy (Johnson & Johnson) Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.9.4 DePuy (Johnson & Johnson) Business Overview 4.10 Genzyme 4.10.1 Genzyme Basic Information 4.10.2 Stem Cell Cartilage Regeneration Product Profiles, Application and Specification 4.10.3 Genzyme Stem Cell Cartilage Regeneration Market Performance (2015-2020) 4.10.4 Genzyme Business Overview 5 Global Stem Cell Cartilage Regeneration Market Analysis by Regions 5.1 Global Stem Cell Cartilage Regeneration Sales, Revenue and Market Share by Regions 5.1.1 Global Stem Cell Cartilage Regeneration Sales by Regions (2015-2020) 5.1.2 Global Stem Cell Cartilage Regeneration Revenue by Regions (2015-2020) 5.2 North America Stem Cell Cartilage Regeneration Sales and Growth Rate (2015-2020) 5.3 Europe Stem Cell Cartilage Regeneration Sales and Growth Rate (2015-2020) 5.4 Asia-Pacific Stem Cell Cartilage Regeneration Sales and Growth Rate (2015-2020) 5.5 Middle East and Africa Stem Cell Cartilage Regeneration Sales and Growth Rate (2015-2020) 5.6 South America Stem Cell Cartilage Regeneration Sales and Growth Rate (2015-2020)

Continued

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Stem Cell Cartilage Regeneration Market 2020 Global Industry Size, Segments, Share and Growth Factor Analysis, Top Key Players Research Report 2026 |...

Global Stem Cell Assay Market 2020: Business Opportunities, Industry Size & Share, Key Applications, Demands, Growth, Trends Analysis and Forecast…

By Stell Cell Research

Final Report will add the analysis of the impact of COVID-19 on this industry.

Global Stem Cell Assay Market Research Report 2015-2026 is a historical overview and in-depth study on the current & future market of the Stem Cell Assay industry. The report represents a basic overview of the Stem Cell Assay market share, status, competitor segment with a basic introduction of key vendors, top regions, product types and end industries. This report gives a historical overview of the Stem Cell Assay market trends, growth, revenue, capacity, cost structure, and key drivers analysis.

Request a sample copy of the report https://www.industryresearch.biz/enquiry/request-sample/15874875

The report offers detailed coverage of the Global Stem Cell Assay market which includes industry chain structure, definitions, applications, and classifications. The global Stem Cell Assay market analysis is provided for the international markets including development trends, competitive landscape analysis, investment plan, business strategy, opportunity, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, industry share, policy, price, revenue and gross margins.

The demand of global stem cell assay is increasing.

Market Analysis and Insights: Global Stem Cell Assay Market

The global Stem Cell Assay market size is projected to reach US$ 843 million by 2026, from US$ 750.5 million in 2020, at a CAGR of 11.4%% during 2021-2026.

Global Stem Cell Assay Scope and Market Size

Stem Cell Assay market is segmented by Type, and by Application. Players, stakeholders, and other participants in the global Stem Cell Assay market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2015-2026.

Enquire before purchasing this report https://www.industryresearch.biz/enquiry/pre-order-enquiry/15874875

Report Scope And Segmentation Table:

Types:

Viability, Purification, Identification,

Applications:

Regenerative Medicine, Clinical Research,

Key Players:

Merck, Thermo Fisher Scientific, GE Healthcare, Agilent Technologies, Bio-Rad Laboratories, Promega, Cell Biolabs, PerkinElmer, Miltenyi Biotec, HemoGenix, Bio-Techne, STEMCELL,

CAGR 2021-2026:

11.4%

Market Size 2020:

USD 750.5 million

Market Size 2026:

USD 843 million

Historical Years:

2015-2019

Base Year:

2019

With tables and figures helping analyze worldwide Global Stem Cell Assay market growth, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

Purchase this report (Price 3900 USD for a single-user license) https://www.industryresearch.biz/purchase/15874875

Stem Cell Assay Market Report Contains Following Points in TOC:

Chapter 1: Stem Cell Assay Market Product Overview, Market Segment, Size, Sales, Growth Rate, Price by Type

Chapter 2: Global Stem Cell Assay Market Competition, Sales, Price, Base Distribution, Sales Area, Product Types, and Trends by Company

Chapter 3: Stem Cell Assay Company Basic Information, Manufacturing Base and Competitors, Product Category, Applications and Specifications, Price and Gross Margin (2015-2026)

Chapter 4: Stem Cell Assay Market Status, Size, CAGR, Revenue, Price, Gross Margin and Outlook by Regions

Chapter 5: Stem Cell Assay Market Sales, and Share Segment by Application/End Users

Chapter 6: Global Stem Cell Assay Market Sales, Revenue, Growth Rate Forecast (2021-2026)

Chapter 7: Stem Cell Assay Upstream Raw Materials, Price, Key Suppliers, Cost Structure, Manufacturing Expenses, Industrial Chain Analysis

Chapter 8: Marketing Strategy Analysis, Distributors

Chapter 9: Research Findings and Conclusion

Detailed TOC of Global Stem Cell Assay Market @ https://www.industryresearch.biz/TOC/15874875

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Global Stem Cell Assay Market 2020: Business Opportunities, Industry Size & Share, Key Applications, Demands, Growth, Trends Analysis and Forecast...

New Study Finds Novel Hyperbaric Oxygen Therapy Protocol Can Improve Cognitive Function of Healthy Older Adults – Yahoo Finance

By Stell Cell Research

Research from the Sagol Center for Hyperbaric Medicine and Research Published in Peer Reviewed Journal Aging first to Show Enhanced Brain Function and Improved Cognitive Capabilities Resulting from Novel Hyperbaric Oxygen Therapy Treatment

TEL AVIV, Israel, July 15, 2020 /PRNewswire/ -- The Sagol Center for Hyperbaric Medicine and Researchat Shamir Medical Center, and Tel Aviv University today announced that, for the first time in humans, a peer-reviewed study has demonstrated that hyperbaric oxygen therapy (HBOT) can significantly enhance the cognitive performance of healthy older adults.

The main areas of improvement were attention, information processing speed and executive function, in addition to global cognitive function, all of which typically decline with age. Moreover, there was a significant correlation between the cognitive changes and improved cerebral blood flow in specific brain locations.

The study was published on July 15, 2020 in the peer reviewed journal Aging, entitled: Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial.

Professor Shai Efrati and Dr. Amir Hadanny designed the study based on a unique HBOT protocol developed at the Sagol Center over the past 10 years. The randomized controlled clinical trial included 63 healthy adults (>64) who underwent either HBOT(n=33) or a control period (n=30) for three months. The study's primary endpoint included a change in general cognitive function measured by a standardized comprehensive battery of computerized cognitive assessments before and after the intervention or control. Cerebral blood flow (CBF) was evaluated by a novel magnetic resonance imaging technique for brain perfusion.

"Age-related cognitive and functional decline has become a significant concern in the Western world. Major research efforts around the world are focused on improving cognitive performance of the so-called 'normal' aging population," said Prof. Efrati, Director of the Sagol Center for Hyperbaric Medicine and Research. "In our study, for the first time in humans, we have found an effective and safe medical intervention that can address this unwanted consequence of our age-related deterioration."

"Over years of research, we have developed an advanced understanding of HBOT's ability to restore brain function. In the past, we demonstrated HBOT's potential to improve/treat brain injuries such as stroke, traumatic brain injury and anoxic brain injury (due to sustained lack of oxygen supply) by increasing brain blood flow and metabolism," explained Amir Hadanny, MDS, Chief Medical Research Officer of TheSagol Center for Hyperbaric Medicine and Research and author of the aging study. "This landmark research could have a far-reaching impact on the way we view the aging process and the ability to treat its symptoms."

During HBOT, the patient breaths in pure oxygen in a pressurized chamber where the air pressure is increased to twice that of normal air. This process increases oxygen solubility in the blood that travels throughout the body. The added oxygen stimulates the release of growth factors and stem cells, which promote healing. HBOT has been applied worldwide mostly to treat chronic non-healing wounds.

There is a growing body of evidence on the regenerative effects of HBOT. Sagol Center researchers have demonstrated that the combined action of delivering high levels of oxygen (hyperoxia) and pressure (hyperbaric environment), leads to significant improvement in tissue oxygenation while targeting both oxygen and pressure sensitive genes, resulting in restored and enhanced tissue metabolism. Moreover, these targeted genes induce stem cell proliferation, reduce inflammation and induce generation of new blood vessels and tissue repair mechanisms.

"The occlusion of small blood vessels, similar to the occlusions which may develop in the pipes of an 'aging' home, is a dominant element in the human aging process. This led us to speculate that HBOT may affect brain performance of the aging population," Prof. Efrati explained. "We found that HBOT induced a significant increase in brain blood flow, which correlated with cognitive improvement, confirming our theory. One can conjecture that similar beneficial effects of HBOT can be induced in other organs of the aging body. These will be investigated in our upcoming research."

Story continues

The research group leader, Professor Shai Efrati, who serves as Director of The Sagol Center for Hyperbaric Medicine and Research, also disclosed his role with Aviv Scientific LTD, which has developed a comprehensive program that includes HBOT treatment, cognitive and physical training and nutritional coaching, to enhance brain and body performance of aging adults based on the Sagol HBOT protocol at Aviv Clinics. Prof. Efrati serves as Chair of Aviv Scientific's Medical Advisory Board.

About the Sagol Center for Hyperbaric Medicine and Research

The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center (formerly Assaf Harofeh Medical Center), is a global leader in advancing the understanding of the impact of hyperbaric medicine on cognitive and physical function. Serving as one of the largest Hyperbaric centers worldwide, the Sagol Center offers highly advanced large multiplace chambers, treating more than 200 patients daily. Research conducted at the Center has proven that brain rejuvenation is possible across a wide range of neurological pathologies and illnesses.

Media Contact:

Nicole Grubner Finn Partners for The Sagol Center for Hyperbaric Medicine and Research +1-929-222-8011 nicole.grubner@finnpartners.com

View original content:http://www.prnewswire.com/news-releases/new-study-finds-novel-hyperbaric-oxygen-therapy-protocol-can-improve-cognitive-function-of-healthy-older-adults-301093757.html

SOURCE The Sagol Center for Hyperbaric Medicine and Research

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New Study Finds Novel Hyperbaric Oxygen Therapy Protocol Can Improve Cognitive Function of Healthy Older Adults - Yahoo Finance

Animal Stem Cell Therapy Market Forecast by 2026: Expected to reach USD 291.6 million, at a CAGR of 37.3% during 2021-2026 – Cole of Duty

By Stem Cell Treatment

Final Report will add the analysis of the impact of COVID-19 on this industry.

Global Animal Stem Cell Therapy Market Research Report 2015-2026 is a historical overview and in-depth study on the current & future market of the Animal Stem Cell Therapy industry. The report represents a basic overview of the Animal Stem Cell Therapy market share, status, competitor segment with a basic introduction of key vendors, top regions, product types and end industries. This report gives a historical overview of the Animal Stem Cell Therapy market trends, growth, revenue, capacity, cost structure, and key drivers analysis.

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The report offers detailed coverage of the Global Animal Stem Cell Therapy market which includes industry chain structure, definitions, applications, and classifications. The global Animal Stem Cell Therapy market analysis is provided for the international markets including development trends, competitive landscape analysis, investment plan, business strategy, opportunity, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, industry share, policy, price, revenue and gross margins.

Animal stem cell therapy is a usage of animals stem cell to treat a disease or disorder. The ability of stem cell is to divide and differentiate into a cell with specialized function useful for repairing body tissues damaged by injury or disease. The animal stem cell therapy process involves three steps which include collection of stem cell sample from animals and preparing the sample to concentrate the stem cells. Finally, the therapy includes transferring the stem cells into the injured site for treatment. Animal stem cell therapy increases the expectancy of life in animals with no side effects. It is available for the treatment of arthritis, degenerative joint disorders, tendon, and ligaments injuries in animals. Stem cell therapy is most often used to treat dogs, cats, and horses. But recent developments made it possible to use animal stem cell therapy in tiger, pig, etc. Present animal stem cell therapy is studied in treatments of the inflammatory bowel, kidney, liver, heart and immune-mediated diseases respectively.

The classification of animal stem cell therapy includes dogs, horses and others. And the proportion of dogs in 2017 is about 50.42%, and the proportion is in increasing trend from 2013 to 2017.

Market Analysis and Insights: Global Animal Stem Cell Therapy Market

In 2019, the global Animal Stem Cell Therapy market size was US$ 31 million and it is expected to reach US$ 291.6 million by the end of 2026, with a CAGR of 37.3% during 2021-2026.

Global Animal Stem Cell Therapy Scope and Market Size

Animal Stem Cell Therapy market is segmented by region, by country, company, type, application and by sales channels. Players, stakeholders, and other participants in the global Animal Stem Cell Therapy market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region, by country, company, type, application and by sales channels for the period 2015-2026.

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Report Scope And Segmentation Table:

Types:

Dogs, Horses, Others,

Applications:

Veterinary Hospitals, Research Organizations,

Key Players:

Medivet Biologics LLC, VETSTEM BIOPHARMA, J-ARM, U.S. Stem Cell, Inc, VetCell Therapeutics, Celavet Inc., Magellan Stem Cells, Kintaro Cells Power, Animal Stem Care, Animal Cell Therapies, Cell Therapy Sciences, Animacel,

CAGR 2021-2026:

37.3%

Market Size 2020:

USD 31 million

Market Size 2026:

USD 291.6 million

Historical Years:

2015-2019

Base Year:

2019

With tables and figures helping analyze worldwide Global Animal Stem Cell Therapy market growth, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

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Animal Stem Cell Therapy Market Report Contains Following Points in TOC:

Chapter 1: Animal Stem Cell Therapy Market Product Overview, Market Segment, Size, Sales, Growth Rate, Price by Type

Chapter 2: Global Animal Stem Cell Therapy Market Competition, Sales, Price, Base Distribution, Sales Area, Product Types, and Trends by Company

Chapter 3: Animal Stem Cell Therapy Company Basic Information, Manufacturing Base and Competitors, Product Category, Applications and Specifications, Price and Gross Margin (2015-2026)

Chapter 4: Animal Stem Cell Therapy Market Status, Size, CAGR, Revenue, Price, Gross Margin and Outlook by Regions

Chapter 5: Animal Stem Cell Therapy Market Sales, and Share Segment by Application/End Users

Chapter 6: Global Animal Stem Cell Therapy Market Sales, Revenue, Growth Rate Forecast (2021-2026)

Chapter 7: Animal Stem Cell Therapy Upstream Raw Materials, Price, Key Suppliers, Cost Structure, Manufacturing Expenses, Industrial Chain Analysis

Chapter 8: Marketing Strategy Analysis, Distributors

Chapter 9: Research Findings and Conclusion

Detailed TOC of Global Animal Stem Cell Therapy Market @ https://www.industryresearch.biz/TOC/15904448

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Animal Stem Cell Therapy Market Forecast by 2026: Expected to reach USD 291.6 million, at a CAGR of 37.3% during 2021-2026 - Cole of Duty

New Study Finds Novel Hyperbaric Oxygen Therapy Protocol Can Improve Cognitive Function of Healthy Older Adults – PRNewswire

By Stem Cell Medicine

TEL AVIV, Israel, July 15, 2020 /PRNewswire/ -- The Sagol Center for Hyperbaric Medicine and Researchat Shamir Medical Center, and Tel Aviv University today announced that, for the first time in humans, a peer-reviewed study has demonstrated that hyperbaric oxygen therapy (HBOT) can significantly enhance the cognitive performance of healthy older adults.

The main areas of improvement were attention, information processing speed and executive function, in addition to global cognitive function, all of which typically decline with age. Moreover, there was a significant correlation between the cognitive changes and improved cerebral blood flow in specific brain locations.

The study was published on July 15, 2020 in the peer reviewed journal Aging, entitled: Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial.

Professor Shai Efrati and Dr. Amir Hadanny designed the study based on a unique HBOT protocol developed at the Sagol Center over the past 10 years. The randomized controlled clinical trial included 63 healthy adults (>64) who underwent either HBOT(n=33) or a control period (n=30) for three months. The study's primary endpoint included a change in general cognitive function measured by a standardized comprehensive battery of computerized cognitive assessments before and after the intervention or control. Cerebral blood flow (CBF) was evaluated by a novel magnetic resonance imaging technique for brain perfusion.

"Age-related cognitive and functional decline has become a significant concern in the Western world. Major research efforts around the world are focused on improving cognitive performance of the so-called 'normal' aging population," said Prof. Efrati, Director of the Sagol Center for Hyperbaric Medicine and Research. "In our study, for the first time in humans, we have found an effective and safe medical intervention that can address this unwanted consequence of our age-related deterioration."

"Over years of research, we have developed an advanced understanding of HBOT's ability to restore brain function. In the past, we demonstrated HBOT's potential to improve/treat brain injuries such as stroke, traumatic brain injury and anoxic brain injury (due to sustained lack of oxygen supply) by increasing brain blood flow and metabolism," explained Amir Hadanny, MDS, Chief Medical Research Officer of TheSagol Center for Hyperbaric Medicine and Research and author of the aging study. "This landmark research could have a far-reaching impact on the way we view the aging process and the ability to treat its symptoms."

During HBOT, the patient breaths in pure oxygen in a pressurized chamber where the air pressure is increased to twice that of normal air. This process increases oxygen solubility in the blood that travels throughout the body. The added oxygen stimulates the release of growth factors and stem cells, which promote healing. HBOT has been applied worldwide mostly to treat chronic non-healing wounds.

There is a growing body of evidence on the regenerative effects of HBOT. Sagol Center researchers have demonstrated that the combined action of delivering high levels of oxygen (hyperoxia) and pressure (hyperbaric environment), leads to significant improvement in tissue oxygenation while targeting both oxygen and pressure sensitive genes, resulting in restored and enhanced tissue metabolism. Moreover, these targeted genes induce stem cell proliferation, reduce inflammation and induce generation of new blood vessels and tissue repair mechanisms.

"The occlusion of small blood vessels, similar to the occlusions which may develop in the pipes of an 'aging' home, is a dominant element in the human aging process. This led us to speculate that HBOT may affect brain performance of the aging population," Prof. Efrati explained. "We found that HBOT induced a significant increase in brain blood flow, which correlated with cognitive improvement, confirming our theory. One can conjecture that similar beneficial effects of HBOT can be induced in other organs of the aging body. These will be investigated in our upcoming research."

The research group leader, Professor Shai Efrati, who serves as Director of The Sagol Center for Hyperbaric Medicine and Research, also disclosed his role with Aviv Scientific LTD, which has developed a comprehensive program that includes HBOT treatment, cognitive and physical training and nutritional coaching, to enhance brain and body performance of aging adults based on the Sagol HBOT protocol at Aviv Clinics. Prof. Efrati serves as Chair of Aviv Scientific's Medical Advisory Board.

About the Sagol Center for Hyperbaric Medicine and Research

The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center (formerly Assaf Harofeh Medical Center), is a global leader in advancing the understanding of the impact of hyperbaric medicine on cognitive and physical function. Serving as one of the largest Hyperbaric centers worldwide, the Sagol Center offers highly advanced large multiplace chambers, treating more than 200 patients daily. Research conducted at the Center has proven that brain rejuvenation is possible across a wide range of neurological pathologies and illnesses.

Media Contact:

Nicole Grubner Finn Partners for The Sagol Center for Hyperbaric Medicine and Research +1-929-222-8011 [emailprotected]

SOURCE The Sagol Center for Hyperbaric Medicine and Research

https://www.shamir.org/en/unique-pages-default-aspx/the-sagol-center-for-hyperbaric-medicine-and-research/

Originally posted here:
New Study Finds Novel Hyperbaric Oxygen Therapy Protocol Can Improve Cognitive Function of Healthy Older Adults - PRNewswire

Orchard Therapeutics Announces Global License Agreements for Stable Cell Line Technology from GSK – BioSpace

By Stem Cell Treatment

BOSTON and LONDON, July 15, 2020 (GLOBE NEWSWIRE) -- Orchard Therapeutics (Nasdaq: ORTX), a global gene therapy leader, today announced that the company has entered into two worldwide royalty-bearing license agreements with GlaxoSmithKline plc (GSK) (LSE/NYSE: GSK) for use of their proprietary lentiviral stable cell line technology (LV-SCLT) for Orchards investigational hematopoietic stem cell gene therapies for Wiskott Aldrich syndrome (OTL-103 for WAS) and transfusion-dependent beta thalassemia (OTL-300 for TDT).

Utilization of a stable cell line provides an opportunity to generate lentiviral vector of consistently high titer and eliminates the need to purchase plasmids prior to the production of each viral vector batch, providing more efficient production processes and shorter lead times, said Bobby Gaspar, M.D., Ph.D., chief executive officer of Orchard. By increasing the efficiency of the vector manufacturing process, this technology can provide a key competitive advantage and supports our focus on manufacturing innovations that enable commercial scalability.

The LV-SCLT permanently and stably enables all the lentiviral vector components to be introduced into a cell line in one step. Selection and expansion of a resulting clonal producer line in either suspension or adherent culture can deliver consistent levels of high titer lentiviral production comparable to those seen using conventional methods. An overview of this technology, co-authored by Orchard and GSK scientists, was presented at the European Society of Gene & Cell Therapy (ESGCT) Annual Congress in October 2019 using work done in the OTL-300 program for TDT*. Under the licenses, GSK has granted patents and pending patent applications related to its LV-SCLT**.

Gaspar continued, We believe the work completed with OTL-300 utilizing a stable cell line can be leveraged and applied to future development plans in OTL-103 for WAS, which will be especially useful in a commercial setting given the large number of patients diagnosed and living with the disease.

Orchard plans to submit a biologics license application (BLA) and marketing authorization application (MAA) for OTL-103 for the treatment of WAS in the U.S. and EU, respectively, in 2021.

The terms of the license are not expected to have a material impact on Orchards financial position or near-term cash needs.

About OTL-103 and WAS OTL-103 is an ex vivo autologous hematopoietic stem cell gene therapy in development for the treatment of Wiskott Aldrich syndrome (WAS). WAS is a life-threatening inherited immune disorder that primarily affects males and is characterized by recurrent and severe infections, autoimmunity, eczema and severe bleeding episodes. It is caused by a mutation in the gene that produces the WAS protein, which results in abnormal function of white blood cells and low platelets. Without treatment, the median survival for children born with WAS is 14 years of age. The global incidence of WAS is estimated to be about one in every 100,000 male births per year***.

About Orchard Orchard Therapeutics is a global gene therapy leader dedicated to transforming the lives of people affected by rare diseases through the development of innovative, potentially curative gene therapies. Our ex vivo autologous gene therapy approach harnesses the power of genetically modified blood stem cells and seeks to correct the underlying cause of disease in a single administration. In 2018, Orchard acquired GSKs rare disease gene therapy portfolio, which originated from a pioneering collaboration between GSK and the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy. Orchard now has one of the deepest and most advanced gene therapy product candidate pipelines in the industry spanning multiple therapeutic areas where the disease burden on children, families and caregivers is immense and current treatment options are limited or do not exist.

Orchard has its global headquarters in London and U.S. headquarters in Boston. For more information, please visit http://www.orchard-tx.com, and follow us on Twitter and LinkedIn.

Availability of Other Information About Orchard Investors and others should note that Orchard communicates with its investors and the public using the company website (www.orchard-tx.com), the investor relations website (ir.orchard-tx.com), and on social media (Twitter and LinkedIn), including but not limited to investor presentations and investor fact sheets, U.S. Securities and Exchange Commission filings, press releases, public conference calls and webcasts. The information that Orchard posts on these channels and websites could be deemed to be material information. As a result, Orchard encourages investors, the media, and others interested in Orchard to review the information that is posted on these channels, including the investor relations website, on a regular basis. This list of channels may be updated from time to time on Orchards investor relations website and may include additional social media channels. The contents of Orchards website or these channels, or any other website that may be accessed from its website or these channels, shall not be deemed incorporated by reference in any filing under the Securities Act of 1933.

Forward-Looking Statements This press release contains certain forward-looking statements about Orchards strategy, future plans and prospects, which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include express or implied statements relating to, among other things, Orchards business strategy and goals, the therapeutic potential of Orchards product candidates, including the product candidate or candidates referred to in this release, Orchards expectations regarding the timing of regulatory submissions for its product candidates, the size of the potential markets for Orchards product candidates, and the effectiveness, efficiencies expected from and expected use of stable cell line technology. These statements are neither promises nor guarantees and are subject to a variety of risks and uncertainties, many of which are beyond Orchards control, which could cause actual results to differ materially from those contemplated in these forward-looking statements. In particular, these risks and uncertainties include, without limitation: the severity of the impact of the COVID-19 pandemic on Orchards business, including on clinical development and commercial programs; the risk that any one or more of Orchards product candidates, including the product candidate or candidates referred to in this release, will not be approved, successfully developed or commercialized; the risk of cessation or delay of any of Orchards ongoing or planned clinical trials; the risk that Orchard may not successfully recruit or enroll a sufficient number of patients for its clinical trials; the risk that prior results, such as signals of safety, activity or durability of effect, observed from preclinical studies or clinical trials will not be replicated or will not continue in ongoing or future studies or trials involving Orchards product candidates; the delay of any of Orchards regulatory submissions; the failure to obtain marketing approval from the applicable regulatory authorities for any of Orchards product candidates or the receipt of restricted marketing approvals; the risk of delays in Orchards ability to commercialize its product candidates, if approved; the risk that the market opportunity for its product candidates may be lower than estimated; and the risk that stable cell line technology is less effective than anticipated or does not yield the expected manufacturing efficiencies. Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements.

Other risks and uncertainties faced by Orchard include those identified under the heading "Risk Factors" in Orchards quarterly report on Form 10-Q for the quarter ended March 31, 2020, as filed with the U.S. Securities and Exchange Commission (SEC) on May 7, 2020, as well as subsequent filings and reports filed with the SEC. The forward-looking statements contained in this press release reflect Orchards views as of the date hereof, and Orchard does not assume and specifically disclaims any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

Contacts

Investors Renee Leck Director, Investor Relations +1 862-242-0764 Renee.Leck@orchard-tx.com

Media Molly Cameron Manager, Corporate Communications +1 978-339-3378 media@orchard-tx.com

*Zeguer JL, Acors S, Rana B, et al. A BAC-cloning platform for development of stable producer cell lines for commercial scale lentiviral vector manufacture. Hum Gene Ther 2019; 30:11, P056

**PCT/EP2016/078336 and PCT/EP2016/078334

***Source: Malik MA, Masab M. Wiskott-Aldrich Syndrome. [Updated 2019 Jun 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539838/

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Orchard Therapeutics Announces Global License Agreements for Stable Cell Line Technology from GSK - BioSpace

Vertex hires BMS vet Atkinson to shore up manufacturing for bustling cell and gene therapy pipeline – FiercePharma

By Stem Cell Treatment

Vertex has long been known for its cystic fibrosis brand, including fast-growing triple-combo med Trikafta. But Vertex has its eyes on much more than cystic fibrosis with a bustling cell and gene therapy pipeline, and now the company's found the manufacturing chief to help it get there.

Vertex has tapped Bristol Myers Squibb veteran E. Morrey Atkinson, Ph.D., as its senior vice president and head of commercial manufacturing and supply chain to help take the drugmaker's growing portfolio across the regulatory finish line.

Atkinson is the first major C-suite hire under new CEO Reshma Kewalramani, who took the helm earlier this year after switching from the chief medical officer role. His hiring will add an experienced hand in cell and gene therapy manufacturing as Kewalramani steers Vertex's growing and diversifiedpipeline to the commercial stage.

Until June, Atkinsonwas senior vice presidentof global manufacturing operations at Bristol and helped lead the manufacturing integration team for Bristol's $74 billion Celgene merger that closed in November.

In his previous roles at Eli Lilly and Cook Pharmica (now Catalent), Atkinson specialized in biologics manufacturing and led clinical productionfor some of the earliest viral vectors used in cell and gene therapies. Atkinson also spearheaded the building and qualification of commercial production facilities in the U.S. and Ireland, Vertex said.

RELATED:Vertex plans major Boston expansion to support gene, cell therapy ambitions

In June 2019, Vertexunveiled its plan to build a new cell and gene therapies research site in Boston after putting down $420 million to acquire Exonis Therapeutics and expand its existing partnership with CRISPR Therapeutics for multiple Duchenne muscular dystrophy candidates.

Vertex followed that investment up with its $950 million buy of Summa Therapeutics in September, adding the biotech'sstem cell-based diabetes treatments into the mix.

In November,Vertex was reportedly in advanced talks to lease a 256,000-square-foot facility in Boston's Innovation Square to house the drugmaker's planned cell and gene therapy unit.Vertex reportedly scoured the greater Boston region for a new foothold, including sites in Cambridge, Waltham and Watertown, but picked Innovation Square because its one of the most advanced projects in the neighborhood, on track to open in 2021.

So far, Vertexhasn't publicly announced the future home for its advanced therapies unit, though.The drugmaker is also running small-molecule investigational candidates in APOL1-mediated kidneydisease, beta thalassemia, sickle disease and alpha-1 antitrypsin deficiency through clinical testing.

RELATED:Vertex CEO Leiden touts gangbusters Trikafta launch in 'mic drop' earnings call

In the meantime, Vertex currently houses its entire continuous manufacturing center for its cystic fibrosis portfolio at a South Boston facility that employs 100, the drugmaker said.

That site has been running at full speed with sales for Vertex's latest CF launch, Trikafta, blowing past analyst consensus on its way to blockbuster status.

In the first quarter, Trikafta hit $895 million in sales after just five months on the market.Those sales are higher than Vertex's three established CF meds combined and put the drug well on track to hitSVB Leerink analyst GeoffreyPorges' prediction of$4.6 billion in annual sales by 2023 and $6.6 billion in 2025.

Trikafta's gangbusters launch came as a fitting sendoff for CEO Jeffrey Leiden, who moved over into the chairman role in favor of then-CMO Kewalramani.

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Vertex hires BMS vet Atkinson to shore up manufacturing for bustling cell and gene therapy pipeline - FiercePharma

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