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In Vitro Toxicology Testing Market to Exhibit Rapid Surge in Consumption in the COVID-19 Crisis 2024 – 3rd Watch News

[112 Report Pages] This market research report identifies Laboratory Corporation of America Holdings, Charles River Laboratories, Inc, Thermo Fisher Scientific, Eurofins Scientific, Agilent Technologies, Inc., as the major vendors operating in the global in vitro toxicology testing market. This report also provides a detailed analysis of the market by toxicology end points (systemic toxicity, cytotoxicity testing, genotoxicity testing, ocular toxicity, organ toxicity, dermal toxicity, neurotoxicity, and others), industry type (pharmaceutical and biopharmaceutical, cosmetics, chemical, diagnostics, and food industry), and region (North America, Europe, Asia Pacific, and Rest of the World).

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Infoholicsmarket research report predicts that theglobalin vitro toxicology testingmarketwill grow at a CAGR of8.2%during the forecast period 20182024.The market for in vitro toxicology testing is driven by high opposition to animal testing, increased cost related to animal-based toxicity testing, and increasing R&D expenditure for early stage toxicity testing. Whereas, the lack of in vitro models and decreased adoption rate are limiting the growth of the in vitro toxicology testingmarket to an extent.

According to the in vitro toxicology testingmarket analysis, Europe accounted for the largest share of the global in vitro toxicology testingmarket followed by North America in 2017. The reason is the upsurge in the investments by the European Commission in R&D to develop substitute methods to in vitro testing is driving the demand in this region. Asia Pacific is expected to grow at a high CAGR during the forecast period due to increasing number of contract research organizations offering testing services, advancements in healthcare infrastructure, increasing investments in the biopharmaceutical sector, and upward economic conditions in the region.

Competitive Analysis and Key Vendors:

There is an increase in collaborations between companies on in vitro testing of compounds. For instance, in December 2016, Evotec and Celgene entered into a drug discovery collaboration for neurodegenerative diseases. According to agreement terms, Celgene will use Evotecs unique induced pluripotent stem cell (iPSC) platform that enables systematic drug screening in patient-derived disease models. In June 2017, Censo Biotechnologies Ltd. collaborated with Evotec AG to source and provide patient-derived induced pluripotent stem cells to support Evotecs drug discovery iPSC platform. In addition, the companies are also coming up with new products for in vitro testing. For instance, in January 2018, STEMCELL Technologies Inc. released two product lines for organoid research that will enable scientists to create powerful models for studying human disease in the laboratory.

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Some of the In Vitro Toxicology Testing Market key vendorsare:

Other prominent vendors in the global in vitro toxicology testing market are Bio-Rad Laboratories, GE Healthcare, SGS SA, BioIVT, Abbott Laboratories, Gentronix Limited, Promega Corporation, MB Research Laboratories, Evotec AG (Cyprotex plc), Catalent, Inc., Qiagen N.V., and niche players.

In Vitro Toxicology Testing Market by Toxicology End Points:

In 2017, the systemic toxicity accounted for the highest market share due to the availability of a wide range of sub-studies, which ensure total analysis of toxicity and safety margin of the testing compounds.

In Vitro Toxicology Testing Market by Industry type:

In 2017, the pharmaceutical and biopharmaceutical industry occupied significant market share and the cosmetics industry is expected to hold a high percentage during the forecast period. Increased support of regulatory authorities to use in vitro and in silico methods instead of animal testing to check toxicology is driving the growth of the cosmetic industry.

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In Vitro Toxicology Testing Market Benefits:

The report provides detailed information about the services offered by in vitro toxicology testingin various therapeutic verticals and regions. With that, key stakeholders can find out the major trends, drivers, investments, and vertical players initiatives. Moreover, the report provides details about the major challenges that are going to have an impact on market growth. Additionally, the report gives complete details about the business opportunities to key stakeholders to expand their business and capture revenues in the specific verticals. The report will help companies interested or established in this market to analyze the various aspects of this domain before investing or expanding their business in the in vitro toxicology testingmarket.

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In Vitro Toxicology Testing Market to Exhibit Rapid Surge in Consumption in the COVID-19 Crisis 2024 - 3rd Watch News

First time ever successful operation with a single-use endoscope on immunodepressed child – Emergency-Live

The advantage of a single-use endoscope is that, since they do not have to be sanitized and reprocessed they do not expose to the danger of infections during endoscopic procedures. Thats why they turned out to be so useful in immunodepressed patients, like the child of this case.

Given the high costs, they are reserved for immunodepressed adult patients and have come back of great use in the middle of the pandemic emergency from COVID-19.

At the Policlinico Universitario A. Gemelli IRCCS (Italy) the disposable endoscope Exalt has been successfully used for the first time also on a pediatric immunodepressed child with congenital immunodeficiency. Thanks to the UOC team of Digestive Surgical Endoscopy directed by Professor Guido Costamagna, Professor of General Surgery at the Catholic University in Rome, this operation was possible-

Below, the official communication by Policlinico Gemelli.

Exalt is the name of the brand-new disposable endoscope model and was first used in the world at Policlinico Gemelli. It has been used to assist a 7-year-old child suffering from biliary narrowing who was dilated with this high-tech instrument, explains the note.

The most important thing about these disposable instruments (the one used is Boston Scientifics Exalt Model-D) is that, although expensive, they overcome all the problems linked to the meticulous disinfection and reprocessing that traditional endoscopes undergo after each use. When operating immunodepressed patients, such as the little patient admitted to the Policlinico Gemelli suffering from a very rare form of congenital immunodeficiency (DOCK8 deficiency, Dedicator of Cytokinesis 8), this fact is very important.

This rare disease exposed this child to a very high risk of infection.

The patient had developed primary sclerosing cholangitis while waiting for a hematopoietic stem cell transplant (marrow transplant). This is a disease that affects the biliary tract that causes bile to flow from the liver to the gallbladder and then to the duodenum and a narrowing of the biliary sphincter, to be treated by biliary sphinctomy using the ERCP (Endoscopic retrograde cholangiopancreatography) procedure, i.e. an incision of the outlet of the biliary tract in the duodenum, which is performed in endoscopy.

It is a delicate operation but necessary to prevent the stagnation of bile in the biliary tract. This may cause a possible infection (cholangitis), very dangerous in immunodepressed children, continues the official note of the polyclinic.

The endoscopic surgery was performed at the beginning of this month and the little one, assisted in collaboration with the doctors of the Pediatric Oncology Unit of Policlinico Gemelli, was discharged in excellent condition 48 hours after the treatment.

So far the Exalt single-use duodenoscope has been used only on adult patients, explains Professor Guido Costamagna director of the UO of Digestive Surgical Endoscopy Department. At Policlinico Gemelli, the medical staff have had it available since last March and they used it to treat two COVID-19 patients, in the middle of the pandemic.

For the first time in the world, we used this disposable endoscope on a 7-year-old girl weighing just 24 kilos.

The single-use endoscope (a duodenoscope, precisely) represents a still expensive device, but certainly very useful in selected cases, such as immunodepressed patients. According to our experience, Exalt can be used safely even in small pediatric patients.

The Exalt Model-D, the worlds first single-use endoscope was awarded by the US Food and Drug Administration (FDA) with the Breakthrough Device Designation last December and received the CE mark in January this year, concludes the official note.

Each year, 1.5 million ERCP procedures are performed worldwide, 500,000 of which are performed in Europe.

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Primary Sclerosing Cholangitis

SOURCE

Official Website of Policlinico Gemelli

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First time ever successful operation with a single-use endoscope on immunodepressed child - Emergency-Live

Quick and Simple Technology Enhances the Potential of Stem Cells To Differentiate Into Adult Cells – Technology Networks

Mouse embryoid body with multiple cell types (in different colours) generated in vitro after expression of miR-203 in stem cells. Credit: CNIO

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Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called mother cell because of its ability to give rise to a variety of different cell types, can be applied in regenerative medicine for diseases such as muscular and nervous system disorders, among others. Researchers and stem cell pioneers Sir John B. Gurdon and Shinya Yamanaka received the Nobel Prize in Physiology and Medicine in 2012 for this idea. However, one of the main limitations in the application of these cell therapies is the quality of the stem cells that can be generated in the laboratory, which impedes their use for therapeutic purposes. Now, a team from the Cell Division and Cancer Group of the Spanish National Cancer Research Centre (CNIO), led by researcher Marcos Malumbres, has developed a new, simple and fast technology that enhances in vitro and in vivo the potential of stem cells to differentiate into adult cells. The research results are published in The EMBO Journal.

In recent years, several protocols have been proposed to obtain reprogrammed stem cells in the laboratory from adult cells, but very few to improve the cells we already have. The method we developed is able to significantly increase the quality of stem cells obtained by any other protocol, thus favouring the efficiency of the production of specialised cell types, says Mara Salazar-Roa, researcher at the CNIO, first author of the article and co-corresponding author.

In this study, the researchers identified an RNA sequence, called microRNA 203, which is found in the earliest embryonic stages before the embryo implants in the womb and when stem cells still have their maximum capacity to generate all the different tissues. When they added this molecule to stem cells in the laboratory, they discovered that the cells ability to convert to other cell types improved significantly.

To corroborate this, they used stem cells of human and murine origin, and of genetically modified mice. The results were spectacular, both in mouse cells and in human cells. Application of this microRNA for just 5 days boosts the potential of stem cells in all scenarios we tested and improves their ability to become other specialised cells, even months after having been in contact with the microRNA, says Salazar-Roa.

According to the study, cells modified by this new protocol are more efficient in generating functional cardiac cells, opening the door to an improved generation of different cell types necessary for the treatment of degenerative diseases.

Malumbres, head of the CNIO Cell and Cancer Division Group, says: To bring this asset to the clinic, collaboration with laboratories or companies that want to exploit this technology is now necessary in each specific case. In this context, Salazar-Roa recently participated, in close collaboration with the CNIOs Innovation team, in prestigious innovation programs such as IDEA2 Global of the Massachusetts Institute of Technology (MIT) and CaixaImpulse of the la Caixa Foundation, from which they also obtained funding to start the development of this technology.

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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Quick and Simple Technology Enhances the Potential of Stem Cells To Differentiate Into Adult Cells - Technology Networks

California voters: Here are the 12 measures on the November ballot – San Francisco Chronicle

Californians will see a lengthy list of initiatives and referendums on the November ballot.

Secretary of State Alex Padilla has assigned proposition numbers to 12 measures that have qualified for the ballot, from funding for stem cell research to a repeal of the states ban on affirmative action and an expansion of consumer privacy laws. Each must be approved by a simple majority to become law.

Proposition 14: Stem cell research. Would re-fund the California Institute for Regenerative Medicine, the states stem cell agency, by allowing it to issue $5.5 billion in bonds for research, training and facilities construction.

Proposition 15: Limits on property taxes. Would rewrite Proposition 13, the landmark 1978 measure that limits property tax increases and allows residential and commercial property to be reassessed only when it is sold.

Prop. 15 would boost property taxes on large commercial and industrial property by allowing it to be reappraised more frequently. The added money would go to school districts and local governments. Prop. 13 rules for residential property would be unchanged.

Proposition 16: Affirmative action. A constitutional amendment, proposed by state legislators, that would reverse Californias voter-approved 1996 ban on affirmative action. It would repeal Proposition 209, which prohibits public universities, schools and government agencies from using race or sex in their admissions criteria, hiring and contract decisions.

Proposition 17: Parolee voting. A constitutional amendment, proposed by state legislators, that would restore the voting rights of all people on parole if theyve completed their state or federal prison terms.

Proposition 18: Voting age. A constitutional amendment, proposed by state legislators, that would allow 17-year-olds to vote in primary elections if they would turn 18 before the general election.

Proposition 19: Property tax transfers. A constitutional amendment, proposed by state legislators, that would allow people age 55 and older, and victims of wildfires and other disasters, to keep lower property tax rates when they move to new homes.

Proposition 20: Criminal justice. Would make changes to the criminal justice system by revising two earlier initiatives, Proposition 47 and Proposition 57. The new measure would expand the list of violent crimes for which there is no early release, adding sex trafficking of a child and felony domestic violence. It would also require DNA collection for those convicted of several types of misdemeanors.

Proposition 21: Rent control. Would reverse a ban on local rent control laws. It would repeal the Costa-Hawkins Rental Housing Act, which prohibits cities from passing rent control ordinances for housing built since 1995. Voters overwhelmingly rejected a similar measure in 2018.

An earlier version of this story erroneously stated that two additional measures could qualify for the November ballot. The window for qualifying has closed.

Proposition 22: Gig worker classification. Would exempt app-based drivers, including those working for Uber, Lyft and DoorDash, from a state law that classifies gig workers as employees. The companies want to undo part of AB5, Californias gig-worker law, which aims to classify their drivers as employees and make them eligible for benefits. Under the ballot measure, the companies could keep drivers as independent contractors while granting them some benefits and earnings guarantees.

Proposition 23: Kidney dialysis clinics. Would increase state regulation of kidney dialysis clinics. Among the proposed requirements: Clinics would be prohibited from discriminating against patients based on their source of payment.

Proposition 24: Consumer data privacy. Would expand Californias consumer privacy law, passed in 2018. The measure would triple penalties for companies that break laws regarding the collection and sale of childrens private information. It would also create a state agency to enforce consumer privacy protections.

Proposition 25: Cash bail. Would overturn a 2018 law that eliminates cash bail as a requirement to release people from jail before trial.

Dustin Gardiner is a San Francisco Chronicle staff writer. Email: dustin.gardiner@sfchronicle.com Twitter: @dustingardiner

Dustin Gardiner is a state Capitol reporter for The San Francisco Chronicle. He joined The Chronicle in 2019, after nearly a decade with The Arizona Republic, where he covered state and city politics. Dustin won several awards for his reporting in Arizona, including the 2019 John Kolbe Politics Reporting award, and the 2017 Story of the Year award from the Arizona Newspapers Association. Outside of work, he enjoys hiking, camping, reading fiction and playing Settlers of Catan. He's a member of NLGJA, the association of LGBTQ journalists.

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California voters: Here are the 12 measures on the November ballot - San Francisco Chronicle

Stem Cell Banking Market Global Industry Analysis and Opportunity and Forecast 2018 to 2028 – Cole of Duty

Global Stem Cell Banking Market: Overview

The demand within the global stem cell banking market is growing on account of advancements in the field of regenerative medicine. The medical fraternity has become extremely focused towards the development of artificial tissues that can infuse with the human body. Furthermore, medical analysis and testing has gathered momentum across biological laboratories and research institutes. Henceforth, it is integral to develop stem cell samples and repositories that hold relevance in modern-day research. The need for regenerative medicine emerges from the growing incidence of internal tissue rupture. Certain types of tissues do not recover for several years, and may even be damaged permanently. Therefore, the need for stem cell banking is expected to grow at a significant pace.

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In a custom report, TMR Research digs into the factors that have aided the growth of the global stem cell banking market. The global stem cell banking market can be segmented on the basis of bank size, application, and region. The commendable developments that have incepted across the US healthcare industry has given a thrust to the growth of the North America stem cell banking market.

Global Stem Cell Banking Market: Notable Developments

The need for improved regenerative medication and anatomy has played an integral role in driving fresh developments within the stem cell banking market.

Gallant has emerged as a notable market entity that has remained as the torchbearer of innovation within the global stem cell banking market. The company has recently launched stem cell banking for dogs, and has attracted the attention of the masses. As people become increasingly concerned about their pets, the new move by Gallant shall help the company in earning the trust of the consumers. Moreover, it can move several notches higher on the innovation index.

Cells4Life has also remained at the forefront of developments within the global stem cell banking market. After suffering backlash for its error in cord blood stem cell promotion, the company is expected to use effective public relation strategies to regain its value in the market.

Global Stem Cell Banking Market: Growth Drivers

Development of improved facilities for storage of stem cells has played an integral role in driving market demand. Furthermore, the unprecedented demand for improved analysis of regenerative medications has also created new opportunities within the global stem cell banking market. Medical research has attracted investments from global investors and stakeholders. The tremendous level of resilience shown by biological researchers to develop stem cell samples has aided market growth. Henceforth, the total volume of revenues within the global stem cell banking market is slated to multiply.

Commercialization of stem cell banks has emerged as matter of concern for the healthcare industry. However, this trend has also helped in easy storage and procurement of cells stored during the yester years of children. Presence of sound procedures to register at stem cell banks, and the safety offered by these entities, has generated fresh demand within the global market. New regional territories are opening to the idea of stem cell banking. Several factors are responsible for the growth of this trend. Primarily, improvements in stem cell banking can have favourable impact on the growth of the healthcare industry. Moreover, the opportunities for revenue generation associated with the development of functional stem cell banks has aided regional market growth.

The global stem cell banking market is segmented on the basis of:

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Stem Cell Banking Market Global Industry Analysis and Opportunity and Forecast 2018 to 2028 - Cole of Duty

Props To You, Californians: A Preview Of What’s On Your November Ballot – KPBS

After a bit of last-minute legislative maneuvering, the list of propositions that California voters will be asked to weigh in on has been more or less finalized.

This past week marked the deadline for citizens and special interests to snag their spot on the November ballot. Eight measures made the cut. They address matters as vital and/or esoteric as rent control, property tax law, dialysis clinic staffing requirements, stem cell research funding and the preservation or final dispatch of cash bail in California.

The same date also marked the deadline for legislators to place their preferred measures on the November ballot. But lawmakers have a bit more flexibility when it comes to deadlines they can just make new laws. On Monday, the Senate passed Senate Bill 300 to Gov. Gavin Newsom who signed it. The law effectively extended the Legislatures deadline to July 1.

(Technically, the deadline wasnt extended but created anew. The law calls for the Legislatures favored measures to go before voters in a whole new election conveniently to take place on the same day and same ballot as the ordinary November 3 election.)

That extension gave lawmakers a few extra hours to add four measures: two to expand voting rights, one that ends a 22-year-old ban on affirmative action, and one that is a tortuously complicated property tax measure that somehow ropes in Realtors, wildland firefighters and The Dude from the Big Lebowski.

Heres your November ballot preview:

These three measures, all placed on the ballot by the Legislature, had been introduced before protests against racism and police brutality swept the country. But as California lawmakers look for ways to play a role in the national debate about institutional barriers to equity and the meaning of citizenship, many legislators see these as particularly potent causes.

Prop. 16: Ending the ban on affirmative action

Who put it there: The Legislature, via a bill by San Diego Democrat Assemblymember Shirley Weber

Type: Constitutional amendment

What it would do: Allow schools and public agencies to take race and other immutable characteristics into account when making admission, hiring or contracting decisions.

In 1996 California voters passed Proposition 209, a constitutional amendment banning affirmative action at state institutions. The result was an immediate drop in Black and Latino enrollment at the states elite public universities. Some civil rights organizations have been trying to repeal Prop. 209 ever since.

Each of those attempts has been stymied by a coalition of Republicans, moderate Democrats and some progressive legislators who represent districts with large Asian American voting populations. This year, as in previous years, some of the most vocal and persistent opponents of the effort to reintroduce affirmative action have been Chinese-American political activists. They argue that boosting enrollment of students from underrepresented racial groups would come at the expense of overrepresented Asian American students.

Prop. 17: Restoring the right to vote to people on parole

Who put it there: The Legislature, via a bill by Sacramento Democrat Assemblymember Kevin McCarty.

Type: Constitutional amendment

What it would do: Allow Californians who are currently on parole to vote.

In 1974, California voters passed a ballot measure giving people who have committed felonies the right to vote once they complete their sentences and are no longer on parole.

Thanks to that law, there are some 40,000 Californians who are not in prison but unable to legally cast a ballot. But as with any criminal justice debate, this is also one about race. According to an estimate from 2016, two thirds of people on parole in the state are Latino or Black.

Prop. 18: Letting (some) 17 year olds vote (some of the time)

Who put it there: The Legislature, with a bill introduced by San Mateo Democrat Assemblymember Kevin Mullin.

Type: Constitutional amendment

What it would do: Allow 17-year-old U.S. citizens to vote in a primary and special election as long as they will turn 18 by the subsequent general election.

California Democrats have been on a decade-long tear increasing voting access. Same-day voter registration, automatic registration at the DMV and pre-registration of 16- and 17-year-olds are among the recent pro-vote innovations to come out of the Capitol.

Letting people under 18 vote would be yet another extension. Already 23 states let 17- year-olds vote in certain circumstances.

Democratic legislators have tried to do this six times before; this is the first to make the ballot.

This wouldnt be a California election without at least a few wildy contentious ballot measures about housing and property taxes.

Prop. 15: Split roll

Who put it there: Citizens. Campaign largely funded by the California Teachers Association, SEIU California and the Chan Zuckerberg Initiative.

Type: Constitutional amendment

What it would do: Tax some commercial property based on its market value, rather than the price at which it was purchased. This would raise property taxes on many large businesses across the state, increasing funding for schools and local government.

In 1978, California voters passed Proposition 13, placing a cap on property taxes, kicking off a nationwide anti-tax revolt and placing city and county budgets in a generation-spanning straitjacket.

By tying a landlords property tax payments to the original purchase price, Prop. 13 has been the gift that keeps on giving to property owners, particularly those lucky enough to have bought cheap real estate decades ago. Theres been bipartisan reluctance among lawmakers to touch it ever since, lest they incur the wrath of irate homeowners.

This initiative attempts to divide and conquer that political problem by repealing the property tax protections only for commercial landlords with more than $3 million in holdings. If this measure passes, those landowners would have to make tax payments based on the current value of their properties a tax hike for most resulting in an estimated $6.5 to $11.5 billion more for cities, counties and school districts.

Prop. 19: Property tax breaks and closing the Lebowski loophole

Who put it there: The Legislature, via a bill by San Mateo Democrat Assemblymember Kevin Mullin, but sponsored by the California Realtors.

Type: Constitutional amendment

What it would do: Allow homeowners who are over 55, disabled or victims of natural disaster to take a portion of their property tax base with them when they sell their home and buy a new one. It would also limit the ability of new homeowners who inherit properties to keep their parents or grandparents low property tax payments. Most of the additional money raised would go into a state fire response fund.

Weve seen this one before half of it, anyway. In 2018, the California Association of Realtors put a measure on the ballot allowing older or disabled homeowners to keep a portion of their Prop. 13 tax break. The Realtors argued that the current property tax rules disincentivize longtime homeowners from moving, trapping empty-nesters in houses that are too big for them and locking out new families. But because the measure would cost schools, counties and cities, it was opposed by organized labor and local government groups and failed by 20 points.

The Realtors tried again this year, but with an added fiscal sweetener. Under this proposal, anyone who inherits a home from their parents or grandparents would only be allowed to keep the low property taxes if they use the home as their primary residence and only on the first $1 million between the homes original purchase price and its market value. Inspiration for that caveat may have come from the Los Angeles Times, which tracked down a number of California scions, including The Big Lebowski star Jeff Bridges, who are still paying 1970-era property tax levels on their rental properties.

And then there was a last-minute wrinkle. In the final weeks of June, the Realtors sprang a deal: designating that most of the funding generated by the measure would go to fighting wildfires. That won the support of the influential California Professional Firefighters union. It also means the measure will be funding a public need that might be on many voters minds come November.

That bargain was struck after the Realtors had submitted their signatures, so with the help of Assemblyman Mullin, they passed it through the Legislature, pulling their original proposal just before the deadline.

Who put it on the ballot: Signatures, collected via an effort mostly funded by the AIDS Healthcare Foundation.

Type: Statute

What it would do: Allow cities to introduce new rent control laws, or expand existing ones.

Despite a 20-percentage point, 56-out-of-58 county defeat in 2018, a statewide rent control measure is back on the ballot.

Polling from that election season suggested that California voters generally liked rent control as a concept, but worried about the specifics of the proposal. Accordingly, this new initiative makes a few tweaks.

Under this one, cities would be allowed to apply new rent control ordinances only to homes that are at least 15 years old. And it exempts single-family homes owned by landlords with no more than two properties.

Just like last time, the measure is being pushed by the Los Angeles-based AIDS Healthcare Foundation and its pugnacious president Michael Weinstein. State lawmakers by passing a law last year that set a 7% ceiling on how much landlords can raise rents each year had hoped to ward off another attempt by Weinstein and company. They had no such luck.

California, the home of three-strikes sentencing, has spent the last decade rethinking its approach to criminal justice. Two measures on the November ballot, channeling the spirit of the 90s, are pushing to reverse that reversal.

Prop. 25: Ditch or keep cash bail

Who put it there: Signatures, via a campaign largely funded by the bail bond industry.

Type: Referendum

What it would do: Ask voters to either approve or strike down a state law that banished money bail from the state criminal justice system.

In 2018, acting on the advice of state Supreme Court Chief Justice Tani Cantil-Sakauye, legislators passed a bill ending cash bail in California. Rather than letting people pay their way out of jail while they await trial, the law gives judges the right to determine whether someone who is arrested should be kept behind bars based on the risk they are deemed to pose to themselves or others.

Moving quickly, the bail bond industry mounted a campaign to put the question on the ballot as a referendum. Voters will vote either Yes to keep the state law and end cash bail for good, making California the first state to do so, or No to keep the bail system.

Prop. 20: Rolling back Brown-era leniency

Who put it there: Signatures, via a campaign largely funded by law enforcement agencies.

Type: Constitutional amendment

What it would do: Allow prosecutors to charge repeat or organized petty theft as a felony, require probation officers to seek tougher penalties for those who violate the term of their parole three times, and exclude those who have been convicted of domestic violence and certain nonviolent crimes from early parole consideration.

Gov. Jerry Brown was famously allergic to talk of his legacy while in office. But if the former governor has one, it might be the effort he spent in his final two terms as governor supporting efforts to reverse the tough on crime policies he helped introduce during his first two terms in the 1970s and 80s.

In 2011, California legislators reduced punishments for parole violators. In 2014, voters passed Proposition 47, recategorizing some non-violent crimes as misdemeanors. In 2016, voters passed Proposition 57, giving inmates convicted of certain non-violent offenses a shot at early release.

This ballot measure would partially undo each of those.

Usually standoffs between employees and their bosses take place behind closed doors. In California, you often find them on the ballot.

Prop. 22: Self-employment for ride-hail and other app-drivers

Who put it there: Signatures, via a campaign mostly funded by Lyft, Uber and Doordash

Type: Statute

What it would do: Turn app-based drivers into independent contractors, exempting companies such as Lyft and Uber from standard wage and hour restrictions. It would also guarantee these drivers an earnings floor, a stipend to purchase health insurance and other minimum benefits.

Unless you happen to be an anti-vaccine protestor, the most controversial law of the 2019 legislative session was Assembly Bill 5. On its face, the law simply codified a state Supreme Court ruling, making it much harder for companies to treat their workers as independent contractors, rather than full-fledged employees. In practice, it upended the business models of Uber, Lyft, Doordash, Postmates and Instacart, all of which rely on an army of phone-toting gig-workers to provide their various services.

In the months since, all attempts at legislative compromise have fizzled, Californias Attorney General has sued Uber and Lyft for violating the new law and California regulators declared their drivers to be employees.

As a last-ditch effort, the various companies implicated have poured $110 million and counting to push a ballot measure that would simply exclude their drivers from the law. And throwing a bone to critics who say their drivers are mistreated, the measure also imposes some worker benefits and protections.

Prop. 23: Regulating dialysis clinics

Who put it there: Signatures, via an effort funded entirely by the Service Employees International Union-United Healthcare Workers West

Type: Statute

What it would do: Require dialysis clinics to have at least one physician on site at all times and to report patient infection data to California health officials.

DaVita Kidney Care and Fresenius Medical Care own the majority of the for-profit dialysis clinics in the state. For years, the Service Employees International Union-United Healthcare Workers union has been at war with them.

After unsuccessful efforts to unionize clinic staff, the union sponsored legislation to cap reimbursement rates to clinics and floated an array of possible ballot measures to boost their staff spending and cut their profits. In 2018, the union finally got one on the ballot: Prop 8, which would have set a cap on clinic profit margins.

The measure was soundly defeated, but only after the two companies spent over $111 million, making it the most expensive ballot campaign ever. This one isnt likely to be much cheaper.

Two measures on this years ballot aim to bolster laws and programs already on the books. Both campaigns are led by Bay Area real estate developers with a penchant for ballot box policymaking.

Prop. 24: Stronger consumer privacy laws (again)

Who put it there: Signatures, via a campaign funded entirely by Alastair and Celine Mactaggart.

Type: Statute

What it would do: Strengthen Californias already strongest-in-the-nation consumer privacy law and establish a California Privacy Protection Agency

In 2018, California lawmakers passed the California Consumer Privacy Act, giving consumers the right to find out what data companies are collecting about them, to opt out of having it collected and to have that data scrubbed. It was and remains the only law like it in the county. It was also a compromise. San Francisco real estate developer Alastair MacTaggart had been pushing for an even stricter ballot measure, but the Legislature stepped in, brokering a deal between MacTaggart and the tech industry.

Now MacTaggart is back. Along with setting up a state agency tasked with enforcing state privacy law, the measure would beef up financial penalties for violators and allow consumers to demand that personal information not be shared at all, rather than simply not sold.

Who put it there: Signatures via an effort mostly funded by Robert Klein, JDRF International and Open Philanthropy

Type: Bond

What it would do: Borrow $5.5 billion to fund stem cell research

In 2004, voters passed Proposition 71 to create the California Institute for Regenerative Medicine. The institute exists to channel state money toward stem cell research. Prop 71 also let the state borrow $3 billion to do that.

That pot of cash is now almost empty. Robert Klein, a Silicon Valley real estate developer who led the Prop. 71 effort and became the institutes first board chair, is leading the campaign for more.

Correction: This story has been corrected to reflect that Robert Klein was the first board chair of the California Institute for Regenerative Medicine.

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Korea to invest 2.8 trillion in promoting bio-health sector – Korea Biomedical Review

The government unveiled its plans to invest 2.8 trillion won ($2.3 billion) in developing new key technologies to foster the bio-health industry over the next decade.

The Ministries of Health and Welfare, Science and ICT, and Trade, Industry and Energy said on Friday that two interagency projects -- new drug development and regenerative medicine technology development -- had passed the preliminary feasibility study last month.

The two national projects are part of the Bio-Health Industry Innovation Strategy announced by the government in May last year.

In pursuing new drug development as a state project, the government will provide step-by-step support, starting from basic research, going through nonclinical and clinical trials, and reaching test manufacture and mass production.

According to the viability study, the project will likely create 2.1 trillion won in industrial production for 10 years from 2021, to emerge as the largest R&D project to be conducted by the Ministry of Health and Welfare.

The three ministries said they plan to support the project by abolishing barriers as if they were one ministry. To this end, they have established a unified administrative system for the project by building up their capabilities, providing integrated consultation and support customized to the needs of universities, research institutions, and businesses.

Through the project, the government aims to develop blockbuster new drugs, each with annual sales of more than 1 trillion won ($830 million) over the next decade while enhancing the pharmaceutical industry's competitiveness.

Concerning the development of regenerative medicine technology, the government will provide support throughout the period, from the core basics and the original technology to the clinical stage of therapeutic and therapeutic technologies for regenerative medicines.

The field of regenerative medicine, despite expectations as a future medical technology, has experienced limitations in developing new technologies because of the legal system.

After the National Assembly passed the Act on Safety and Support for Advanced Regenerative Medicine and Advanced Biopharmaceuticals last year, research and development conditions and ecosystems for the regenerative medicine field have made marked improvement.

Encouraged by the brighter prospect, the government has decided to invest 595.5 billion won in this area for 10 years from 2021.

It plans to focus on strengthening the technological competitiveness of stem cell therapy products and core technologies with high potential for future growth, such as gene therapy and tissue engineering materials.

"Through the development of the bio-health industry, we will develop innovative new drugs to treat rare, incurable diseases, protect health sovereignty through localization of pharmaceuticals and medical technologies, and strengthen public health," said Im In-taek, director-general of the Health Industry Policy Bureau in the health and welfare affairs ministry.

Based on the results of the recent preliminary feasibility study, the three related ministries will go all out for the project's success, Im added.

corea022@docdocdoc.co.kr

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Global Stem Cell Assay Market with COVID-19 After Effects Analysis by Key Players | GE Healthcare, Promega Corporation, Thermo Fisher Scientific,…

Stem Cell Assay Industry Overview Competitive Analysis, Regional and Global Analysis, Segment Analysis, Market Forecasts 2026

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The Stem Cell Assay market report also encompasses the details about all the market players that are operating in the Stem Cell Assay market. The market players includeGE Healthcare, Promega Corporation, Thermo Fisher Scientific, Merck KGaA, Bio-Rad Laboratories, Bio-Techne Corporation, Cellular Dynamics International, Cell Biolabs, Hemogenix, Stemcell Technologies.

The market analysis in the Stem Cell Assay market study starts with the market definition and scope. In the next section, there is a brief discussion about the target audience of the market. In the later section, a detailed information about the market growth factors and limitations are discussed along with the market opportunities and challenges that are being faced owing to arise of the pandemic. Research tools and methodologies were used while analyzing the Stem Cell Assay market.

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The major section that covers the overall market description is the market segmentation. The Stem Cell Assay market includes segments{Dermatology Stem Cell Assay, Cardiovascular Stem Cell Assay, Central Nervous System Stem Cell Assay, Oncology Stem Cell Assay, Other}; {Regenerative Medicine & Therapy Development, Drug Discovery and Development, Clinical Research, Other}. To study any market in detail the major components that need to be analyzed are its product type, application, end-use, the solution and the services that are offered. Details about all these segments helps better understand the market size and demand. Every aspect of every single segment was studied carefully and the impact of COVID-19 was also taken into consideration. Both numerical data and subjective information about every segment is included for better understanding. The regional presence of the Stem Cell Assay market is also included. The current market condition in each regions is explained thoroughly as to how the pandemic has affected the Stem Cell Assay market demand in a particular region.

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28 cool health things that started with a Canadian – Regina Leader-Post

Alzheimers in mice

Dr. Peter St George-Hyslopof the Weston Brain Institute identified a number of genes responsible for Alzheimers disease and nerve cell degeneration using mouse models. He has published nearly 400 papers on Alzheimers research.

In the early 2000s, he essentially cured Alzheimers in mice through the discovery that certain types of sugars would block the development of amyloid proteins, one of the hallmarks of Alzheimers.

Genomics

University of Torontos Brenda Andrews pioneered the field of functional genomics and systems biology to discover how genes and their protein products regulate cell function in health and disease. She is also an elected member of the National Academy of Sciences and a specialist in the application of artificial intelligence to personalized medicine.

Kathleen Dickson is a former chief technician from the Montreal Neurological Institute.

John Bergeron is the Emeritus Robert Reford Professor and a Professor of Medicine at McGill University.

Dont miss the latest on COVID-19, reopening and life. Subscribe to Healthings daily newsletterComing Out of COVID.

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28 cool health things that started with a Canadian - Regina Leader-Post

Lungs in Vitro Market 2020 Opportunities, Growth Analysis, Trends and Forecast by 2024 | ATCC, Lonza, Epithelix – 3rd Watch News

Competitive Market Research Report on Global Lungs in Vitro Market with focus on Industry Analysis, Growth Opportunities, Risk Analysis, Current Trends, Competitive Landscape, Investment Strategies and Forecast by 2024.

The report contains in-depth information on all the key aspects of the global Lungs in Vitro market. This report contains important data such as facts & figures, market research, market analysis, SWOT analysis, competitive landscape, regional analysis and future growth prospects. The report also contains qualitative and quantitative research which gives you a detailed analysis of the global Lungs in Vitro market. The report is perfect as you can see information on the recent developments, based on which you can make risk assessments and investments in the Lungs in Vitro industry.

Get The Sample Report PDF with Detail TOC & List of [emailprotected]https://marketresearchport.com/request-sample/5147

Leading Companies Covered:

ATCC, Lonza, Epithelix, Mattek, Emulate, Mimetas, Tissuse, Insphero, Cn Bio

This global Lungs in Vitro market research report has data of all the leading players operating in the industry. From their market shares in the industry, to their growth plans, recent development status, all important information has been compiled in the report to let you get an insightful look at the top players operating in the industry. The report includes the forecasts, analysis and discussion of important industry trends, market size, market share estimates and profiles of the leading industry players.

Market Research is Further Divided into Following Segments:

Market Segmentation by Product Types: 2D Cell Models, 3D Cell Models, Commercial 3D Cell Models, Inhouse 3D Cell Models

Market Segmentation by Applications: Drug Screening, Toxicology, 3D Model Development, Basic Research, Physiologic Research, Stem Cell Research, Regenerative Medicine

Regions Mentioned in the Global Lungs in Vitro Market:

The Middle East and Africa North America South America Europe Asia-Pacific Middle East Oceania Rest of the World

The data of the market research report has been studied, compiled and corroborated by leading industry experts and established authors. The format followed in the report is in accordance with most international market research reports. However, if you have any specific requirements, just get in touch with us, and we will customize the report accordingly as per your needs.

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Table of Content: 1 Industry Overview of Lungs in Vitro 1.1 Brief Introduction of Lungs in Vitro 1.1.1 Definition of Lungs in Vitro 1.1.2 Development of Lungs in Vitro Industry 1.2 Classification of Lungs in Vitro 1.3 Status of Lungs in Vitro Industry 1.3.1 Industry Overview of Lungs in Vitro 1.3.2 Global Major Regions Status of Lungs in Vitro

2 Industry Chain Analysis of Lungs in Vitro 2.1 Supply Chain Relationship Analysis of Lungs in Vitro 2.2 Upstream Major Raw Materials and Price Analysis of Lungs in Vitro 2.3 Downstream Applications of Lungs in Vitro

3 Manufacturing Technology of Lungs in Vitro 3.1 Development of Lungs in Vitro Manufacturing Technology 3.2 Manufacturing Process Analysis of Lungs in Vitro 3.3 Trends of Lungs in Vitro Manufacturing Technology

4 Major Manufacturers Analysis of Lungs in Vitro 4.1 Company 1 4.1.1 Company Profile 4.1.2 Product Picture and Specifications 4.1.3 Capacity, Production, Price, Cost, Gross and Revenue 4.1.4 Contact Information 4.2 Company 2 4.2.1 Company Profile 4.2.2 Product Picture and Specifications 4.2.3 Capacity, Production, Price, Cost, Gross and Revenue 4.2.4 Contact Information 4.3 Company 3 4.3.1 Company Profile 4.3.2 Product Picture and Specifications 4.3.3 Capacity, Production, Price, Cost, Gross and Revenue 4.3.4 Contact Information 4.4 Company 4 4.4.1 Company Profile 4.4.2 Product Picture and Specifications 4.4.3 Capacity, Production, Price, Cost, Gross and Revenue 4.4.4 Contact Information 4.5 Company 5 4.5.1 Company Profile 4.5.2 Product Picture and Specifications 4.5.3 Capacity, Production, Price, Cost, Gross and Revenue 4.5.4 Contact Information 4.6 Company 6 4.6.1 Company Profile 4.6.2 Product Picture and Specifications 4.6.3 Capacity, Production, Price, Cost, Gross and Revenue 4.6.4 Contact Information 4.7 Company 7 4.7.1 Company Profile 4.7.2 Product Picture and Specifications 4.7.3 Capacity, Production, Price, Cost, Gross and Revenue 4.7.4 Contact Information 4.8 Company 8 4.8.1 Company Profile 4.8.2 Product Picture and Specifications 4.8.3 Capacity, Production, Price, Cost, Gross and Revenue 4.8.4 Contact Information 4.9 Company 9 4.9.1 Company Profile 4.9.2 Product Picture and Specifications 4.9.3 Capacity, Production, Price, Cost, Gross and Revenue 4.9.4 Contact Information 4.10 Company ten 4.10.1 Company Profile 4.10.2 Product Picture and Specifications 4.10.3 Capacity, Production, Price, Cost, Gross and Revenue 4.10.4 Contact Information

5 Global Productions, Revenue and Price Analysis of Lungs in Vitro by Regions, Manufacturers, Types and Applications 5.1 Global Production, Revenue of Lungs in Vitro by Regions 2014-2019 5.2 Global Production, Revenue of Lungs in Vitro by Manufacturers 2014-2019 5.3 Global Production, Revenue of Lungs in Vitro by Types 2014-2019 5.4 Global Production, Revenue of Lungs in Vitro by Applications 2014-2019 5.5 Price Analysis of Global Lungs in Vitro by Regions, Manufacturers, Types and Applications in 2014-2019

6 Global and Major Regions Capacity, Production, Revenue and Growth Rate of Lungs in Vitro 2014-2019 6.1 Global Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019 6.2 Asia Pacific Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019 6.3 Europe Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019 6.4 Middle East & Africa Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019 6.5 North America Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019 6.6 Latin America Capacity, Production, Price, Cost, Revenue, of Lungs in Vitro 2014-2019

7 Consumption Volumes, Consumption Value, Import, Export and Sale Price Analysis of Lungs in Vitro by Regions 7.1 Global Consumption Volume and Consumption Value of Lungs in Vitro by Regions 2014-2019 7.2 Global Consumption Volume, Consumption Value and Growth Rate of Lungs in Vitro 2014-2019 7.3 Asia Pacific Consumption Volume, Consumption Value, Import, Export and Growth Rate of Lungs in Vitro 2014-2019 7.4 Europe Consumption Volume, Consumption Value, Import, Export and Growth Rate of Lungs in Vitro 2014-2019 7.5 Middle East & Africa Consumption Volume, Consumption Value, Import, Export and Growth Rate of Lungs in Vitro 2014-2019 7.6 North America Consumption Volume, Consumption Value, Import, Export and Growth Rate of Lungs in Vitro 2014-2019 7.7 Latin America Consumption Volume, Consumption Value, Import, Export and Growth Rate of Lungs in Vitro 2014-2019 7.8 Sale Price Analysis of Global Lungs in Vitro by Regions 2014-2019

8 Gross and Gross Margin Analysis of Lungs in Vitro 8.1 Global Gross and Gross Margin of Lungs in Vitro by Regions 2014-2019 8.2 Global Gross and Gross Margin of Lungs in Vitro by Manufacturers 2014-2019 8.3 Global Gross and Gross Margin of Lungs in Vitro by Types 2014-2019 8.4 Global Gross and Gross Margin of Lungs in Vitro by Applications 2014-2019

9 Marketing Traders or Distributor Analysis of Lungs in Vitro 9.1 Marketing Channels Status of Lungs in Vitro 9.2 Marketing Channels Characteristic of Lungs in Vitro 9.3 Marketing Channels Development Trend of Lungs in Vitro

10 Global and Chinese Economic Impacts on Lungs in Vitro Industry 10.1 Global and Chinese Macroeconomic Environment Analysis 10.1.1 Global Macroeconomic Analysis and Outlook 10.1.2 Chinese Macroeconomic Analysis and Outlook 10.2 Effects to Lungs in Vitro Industry

11 Development Trend Analysis of Lungs in Vitro 11.1 Capacity, Production and Revenue Forecast of Lungs in Vitro by Regions, Types and Applications 11.1.1 Global Capacity, Production and Revenue of Lungs in Vitro by Regions 2019-2024 11.1.2 Global and Major Regions Capacity, Production, Revenue and Growth Rate of Lungs in Vitro 2019-2024 11.1.3 Global Capacity, Production and Revenue of Lungs in Vitro by Types 2019-2024 11.2 Consumption Volume and Consumption Value Forecast of Lungs in Vitro by Regions 11.2.1 Global Consumption Volume and Consumption Value of Lungs in Vitro by Regions 2019-2024 11.2.2 Global and Major Regions Consumption Volume, Consumption Value and Growth Rate of Lungs in Vitro 2019-2024 11.3 Supply, Import, Export and Consumption Forecast of Lungs in Vitro 11.3.1 Supply, Consumption and Gap of Lungs in Vitro 2019-2024 11.3.2 Global Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024 11.3.3 North America Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024 11.3.4 Europe Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024 11.3.5 Asia Pacific Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024 11.3.6 Middle East & Africa Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024 11.3.7 Latin America Capacity, Production, Price, Cost, Revenue, Supply, Import, Export and Consumption of Lungs in Vitro 2019-2024

12 Contact information of Lungs in Vitro 12.1 Upstream Major Raw Materials and Equipment Suppliers Analysis of Lungs in Vitro 12.1.1 Major Raw Materials Suppliers with Contact Information Analysis of Lungs in Vitro 12.1.2 Major Equipment Suppliers with Contact Information Analysis of Lungs in Vitro 12.2 Downstream Major Consumers Analysis of Lungs in Vitro 12.3 Major Suppliers of Lungs in Vitro with Contact Information 12.4 Supply Chain Relationship Analysis of Lungs in Vitro

13 New Project Investment Feasibility Analysis of Lungs in Vitro 13.1 New Project SWOT Analysis of Lungs in Vitro 13.2 New Project Investment Feasibility Analysis of Lungs in Vitro 13.2.1 Project Name 13.2.2 Investment Budget 13.2.3 Project Product Solutions 13.2.4 Project Schedule

14 Conclusion of the Global Lungs in Vitro Industry 2019 Market Research Report

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