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Kleo Pharmaceuticals and Celularity Enter into Research Collaboration to Rapidly Develop Allogeneic NK Cell Combination Therapies for COVID-19 and…

NEW HAVEN, Conn., May 21, 2020 (GLOBE NEWSWIRE) -- Kleo Pharmaceuticals, Inc., a leading company in the field of developing next-generation, fully synthetic bispecific compounds designed to emulate or enhance the activity of biologics, and Celularity, Inc., a leading developer of allogeneic, or off-the-shelf, natural killer (NK) cell therapies, today announced a preclinical research collaboration to rapidly advance synergistic combinations of each companys technology platform as potential treatments for COVID-19 and multiple myeloma.

The collaboration comes at an opportune time for both companies. Earlier this year, Kleo received IND authorization from the U.S. Food and Drug Administration (FDA) to test its CD38-targeting antibody recruiting molecule (ARMTM) in combination with autologous NK cells in a clinical study. In early April, Celularity received FDA authorization to evaluate one of its allogeneic NK cell products, CYNK-001, in COVID-19 infected adults. CYNK-001 is the only cryopreserved allogeneic, off-the-shelf Natural Killer (NK) cell therapy being developed from placental hematopoietic stem cells. It also is being investigated as a treatment for acute myeloid leukemia (AML), multiple myeloma (MM), and glioblastoma multiforme (GBM).

We look forward to working with Celularity to advance the ARMTM technology platform across multiple drug programs, said Doug Manion, MD, CEO of Kleo Pharmaceuticals. Celularitys cryopreserved allogeneic NK cells easily combine with the ARMTM platform, which is expected to facilitate NK cell targeting toward cancerous tumors or sites of viral infection. Celularitys CEO Robert Hariri, MD, PhD added, We quickly realized the advantages of Kleos synthetic bifunctional technology, and the synergistic potential between ARMTM molecules and our allogeneic NK cells. The speed and modularity of the Kleo platform allow for the development of ARMTM-allogeneic NK cell combination therapies across a wide variety of indications.

When used in combination with NK cells, ARMTM molecules behave similarly to chimeric antigen receptors, though their synthetic nature eliminates the need for genetic engineering. ARMTM molecules associate with NK cells via IgG antibodies bound to a first moiety, while also containing an interchangeable and customizable second moiety. Selection of the second moiety can be used to confer affinity of an ARMTM-NK cell complex against a biological target, such as the spike protein of COVID-19 particles or CD38 expressed on the surface of multiple myeloma hematologic tumors, ultimately facilitating NK-cell mediated destruction of target cells. This modular design allows ARMTM molecules to be broadly applicable across a range of drug programs.

About Kleo Pharmaceuticals, Inc.

Kleo Pharmaceuticals is a unique biotechnology company developing next-generation, bispecific compounds designed to emulate or enhance the activity of biologics based on the groundbreaking research of its scientific founder Dr. David Spiegel at Yale University. Kleos compounds are designed to direct the immune system to destroy cancerous or virally infected cells and are currently in development for the treatment of various diseases, including multiple myeloma and COVID-19. Compared to biologics, Kleos compounds are smaller and more versatile, leading to potentially improved safety and efficacy. They are also much faster and more efficient to design and produce, particularly against novel targets. Kleo develops drug candidates based on its proprietary technology platforms, all of which are modular in design and enable rapid generation of novel immunotherapies that can be optimized against specified biological targets and combined with existing cell- or antibody-based therapies. These include Antibody Recruiting Molecules (ARMs) and Monoclonal Antibody Therapy Enhancers (MATEs). Biohaven Pharmaceutical Holding Company (NYSE:BHVN) and PeptiDream Inc. (Nikkei:PPTDF) are investors in Kleo Pharmaceuticals. For more information visit http://kleopharmaceuticals.com.

About Celularity

Celularity, headquartered in Warren, N.J., is a clinical-stage cell therapeutics company delivering transformative allogeneic cellular therapies derived from the postpartum human placenta. Using proprietary technology in combination with its IMPACT platform, Celularity is the only company harnessing the purity and versatility of placental-derived cells to develop and manufacture innovative and highly scalable off-the-shelf treatments for patients with cancer, inflammatory and age-related diseases. To learn more, please visit http://www.celularity.com.

Forward-Looking Statements

This news release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company's management. All statements, other than statements of historical facts, included in this press release regarding the Company's plans and objectives, expectations and assumptions of management are forward-looking statements. The use of certain words, including the words "estimate," "project," "intend," "expect," "believe," "anticipate," "will, "plan," "could," "may" and similar expressions are intended to identify forward-looking statements. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

CONTACT INFORMATION

LifeSci Advisors (Investors)

Irina Koffler

646-970-4681

ikoffler@lifesciadvisors.com

Kleo Pharmaceuticals (Media)

Brian Dowd

(203) 643-9172

bdowd@kleopharmaceuticals.com

Celularity Inc. Media Contact:

Dani Frank

Factory PR

celularity@factorypr.com

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Kleo Pharmaceuticals and Celularity Enter into Research Collaboration to Rapidly Develop Allogeneic NK Cell Combination Therapies for COVID-19 and...

Blocking the deadly cytokine storm is a vital weapon for treating COVID-19 – The Conversation US

The killer is not the virus but the immune response.

The current pandemic is unique not just because it is caused by a new virus that puts everyone at risk, but also because the range of innate immune responses is diverse and unpredictable. In some it is strong enough to kill. In others it is relatively mild.

My research relates to innate immunity. Innate immunity is a persons inborn defense against pathogens that instruct the bodys adaptive immune system to produce antibodies against viruses. Those antibody responses can be later used for developing vaccination approaches. Working in the lab of Nobel laureate Bruce Beutler, I co-authored the paper that explained how the cells that make up the bodys innate immune system recognize pathogens, and how overreacting to them in general could be detrimental to the host. This is especially true in the COVID-19 patients who are overreacting to the virus.

I study inflammatory response and cell death, which are two principal components of the innate response. White blood cells called macrophages use a set of sensors to recognize the pathogen and produce proteins called cytokines, which trigger inflammation and recruit other cells of the innate immune system for help. In addition, macrophages instruct the adaptive immune system to learn about the pathogen and ultimately produce antibodies.

To survive within the host, successful pathogens silence the inflammatory response. They do this by blocking the ability of macrophages to release cytokines and alert the rest of the immune system. To counteract the viruss silencing, infected cells commit suicide, or cell death. Although detrimental at the cellular level, cell death is beneficial at the level of the organism because it stops proliferation of the pathogen.

For example, the pathogen that caused the bubonic plague, which killed half of the human population in Europe between 1347 and 1351, was able to disable, or silence, peoples white blood cells and proliferate in them, ultimately causing the death of the individual. However, in rodents the infection played out differently. Just the infected macrophages of rodents died, thus limiting proliferation of the pathogen in the rodents bodies which enabled them to survive.

The silent response to plague is strikingly different from the violent response to SARS-CoV-2, the virus that causes COVID-19. This suggests that keeping the right balance of innate response is crucial for the survival of COVID-19 patients.

Heres how an overreaction from the immune system can endanger a person fighting off an infection.

Some of the proteins that trigger inflammation, named chemokines, alert other immune cells like neutrophils, which are professional microbe eaters to convene at the site of infections where they can arrive first and digest the pathogen.

Others cytokines such as interleukin 1b, interleukin 6 and tumor necrosis factor guide neutrophils from the blood vessels to the infected tissue. These cytokines can increase heartbeat, elevate body temperature, trigger blood clots that trap the pathogen and stimulate the neurons in the brain to modulate body temperature, fever, weight loss and other physiological responses that have evolved to kill the virus.

When the production of these same cytokines is uncontrolled, immunologists describe the situation as a cytokine storm. During a cytokine storm, the blood vessels widen further (vasolidation), leading to low blood pressure and widespread blood vessel injury. The storm triggers a flood of white blood cells to enter the lungs, which in turn summon more immune cells that target and kill virus-infected cells. The result of this battle is a stew of fluid and dead cells, and subsequent organ failure.

The cytokine storm is a centerpiece of the COVID-19 pathology with devastating consequences for the host.

When the cells fail to terminate the inflammatory response, production of the cytokines make macrophages hyperactive. The hyperactivated macrophages destroy the stem cells in the bone marrow, which leads to anemia. Heightened interleukin 1b results in fever and organ failure. The excessive tumor necrosis factor causes massive death of the cells lining the blood vessels, which become clotted. At some point, the storm becomes unstoppable and irreversible.

One strategy behind the treatments for COVID is, in part, based in part on breaking the vicious cycle of the cytokine storm. This can be done by using antibodies to block the primary mediators of the storm, like IL6, or its receptor, which is present on all cells of the body.

Inhibition of tumor necrosis factor can be achieved with FDA-approved antibody drugs like Remicade or Humira or with a soluble receptor such as Enbrel (originally developed by Bruce Beutler) which binds to tumor necrosis factor and prevents it from triggering inflammation. The global market for tumor necrosis factor inhibitors is US$22 billion.

Drugs that block various cytokines are now in clinical trials to test whether they are effective for stopping the deadly spiral in COVID-19.

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Blocking the deadly cytokine storm is a vital weapon for treating COVID-19 - The Conversation US

HKBU invents nanostructure that stimulates growth of stem cells for Parkinson’s disease treatment – PRNewswire

Parkinson's disease is one of the most common neurodegenerative diseases. It is commonly diagnosed in people over the age of 60. It arises from the degeneration of dopaminergic neurons (i.e., dopamine-producing nerve cells) in the substantia nigra, a complex and critical region of the brain. This results in impaired body movement and issues with the body's motor systems, with common symptoms including shaking and difficulty with walking.

While current treatments cannot cure Parkinson's disease completely, stem cell therapy is one of the most promising potential treatments.It involves cultivating stem cells for differentiation into new and healthy cells, tissues or organs which can then be transplanted to human body to replace damaged or dead cells.

Conventional stem cell culturing techniques require a large number of additional growth factors in a culture medium. The chemicals used may stimulate the growth of cancer cells and increase the risk of developing tumours after transplantation to human body. Besides, the brainlike structures obtained from this method usually poorly resemble their counterparts in the brain. Efficiency of the conventional culturing techniques is low as the process spans more than a month, resulting in a high risk of contamination.

Reducing differentiation time and cancer risk

The pioneering nanomatrix, developed by a research team led by Professor Ken Yung Kin-lam, Professor of the Department of Biology and Dr Jeffery Huang Zhifeng, Associate Professor of the Department of Physics at HKBU, can induce the rapid and specific differentiation of neural stem cells into miniature substantia nigra-like structures (mini-SNLSs). These mini-SNLSs mainly comprise of dopaminergic neurons and they can replace the damaged or degenerated cells in the substantia nigra in the brain.

The nanomatrix consists of a silica plate coated with a nanostructure layer. Thickness of the nanomatrix is only 550 to 730 nm, yet there are trillions of nanozigzag structures on the surface which can initiate the growth of neural stem cells into mini-SNLSs without the use of chemical growth factors.

"When the neural stem cells come into physical contact with our tailor-made nanozigzag matrix in vitro, the 'physical massage' can induce the cells to differentiate rapidly into the desired dopaminergic neurons. A self-organised mini-brain-like structure can be developed in only two weeks with risk of carcinogenesis substantially reduced," said Dr Huang.

Encouraging results in rat models

The research team carried out further laboratory tests with mini-SNLSs in a rat model. They transplanted mini-SNLSs cultured with the nanozigzag matrix into the brains of rats with Parkinson's disease that exhibited severe motor asymmetry and rotation, which are major symptoms of Parkinson's disease.

Starting from the 8th week after the transplantation, all rats showed improvements and a progressive reduction in rotation. In the 18th week, dopaminergic neurons were seen and widely spread around the primary transplantation site. In addition, no tumourlike characteristics were detected. In contrast, rats in the control group without transplantation showed no signs of improvement.

Differentiation of other functional cells

"The results showed that these mini-brain-like structures exhibited excellent survival and functionality in the brains of rats and resulted in the early and progressive improvement of Parkinson's disease in rats in vivo. It lays the foundation for research into stem cell therapies that may ultimately cure Parkinson's disease," said Professor Yung.

"By varying the stiffness, density and arrangement of the nanozigzags, or the shape of the matrix layer, the neural stem cells can be differentiated into different desirable functional cells. The invention has shown great potential for the treatment of other incurable diseases, such as Alzheimer's disease and certain types of cancer," Professor Yung added.

The research discovery was published in the academic journal Advanced Science. The research team has been granted a US patent for the nanozigzag matrix.

Apart from HKBU scientists, the research team also included Dr King Lai Wai-chiu, Associate Professor of the Department of Mechanical and Biomedical Engineering at City University of Hong Kong, and a number of other researchers.

Media enquiries:

Wong Suk-lingof the Communication and Public Relations Office (3411 2119, [emailprotected]).

SOURCE Hong Kong Baptist University (HKBU)

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HKBU invents nanostructure that stimulates growth of stem cells for Parkinson's disease treatment - PRNewswire

Global Stem Cells Group Announces the Launch of its New Division VITA NOVAS – PR Web

VITA NOVAS POSTER

MIAMI (PRWEB) May 21, 2020

Having the cushion of an already established worldwide network and 10 years of experience of GSCG, VITA NOVAS has already gained ground with the inherited reputation of quality, innovation, and professionalism. The VITA NOVAS program delivers micro-nutrients , vitamins and stimulating biological products intravenously, guaranteeing an effective way for the ingredients to become immediately available to the cells. This greatly decreases the time it takes for the medication or supplements to take effect. Patient-centered carved out packages The Shield, the Fighter, and the Lightening are delivered on-demand to homes, offices, or hotels administered by certified healthcare professionals.

Believing on the precept of Prevent-Protect-Thrive, VITA NOVAS aspires to set standards in the industry, and committed to ensure in-home, and personalized patient service; keeping them away from hospitals and emergencies. VITA NOVAS offers infusion packages, mixed with essential fluids, electrolytes, vitamins, and antioxidants as a powerful cocktail to stimulate the immune system and help bolster it to assist in fighting infections and diseases. In-line with the evolved life pattern of social distancing, the process of treatment at VITA NOVAS is as simple as:

Select Your Service Area

Schedule a video consultation with our local doctors to discuss your possible treatment plan

Receive the treatment at home

We have combined elements of Tele-health with Regenerative therapy, IV wellness infusions, and a direct-to-consumer model intending to serve at the patients place of residence, due to convenience and social distancing practices, explains Benito Novas , CEO of VITA NOVAS.

The secret behind the VITA NOVAS program is the provision of assistance and prime incentives to medical professionals. Once a physician joins the network, the company provides training and support that they will need in order to set-up run, and market their practices. They enjoy geography and specialization exclusively as well as a strong network of patients referrals, increased revenues, and conduct consultations from home.

Global Stem Cells Group, with golden track record and experience of a decade, is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products, and solutions. Founded in 2010 by Benito Novas, the company combines dedicated researchers, physicians, patient educators, and solution providers with the shared goal of meeting the growing worldwide need for leading-edge Regenerative Medicine treatments. Global Stem Cells Groups corporate mission is to make the promise of Regenerative medicine a reality for patients around the world. With each of GSCGs six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art regenerative technology, while adhering to the highest medical standards.

VITA NOVAS can help, to find your service area, please visit: http://www.vitanovas.net To know more about the company, visit http://www.stemcellsgroup.com

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Global Stem Cells Group Announces the Launch of its New Division VITA NOVAS - PR Web

Not All Cancer Research Money Is Going Away During COVID University of Chicago Receives $10-million Gift For Cell Therapy – SurvivorNet

As the coronavirus pandemic goes on, cancer researchers around the country tell SurvivorNet that they fear their funding will be diverted to research on the virus. However there are bright spots. The University of Chicago says it just received a $10 million gift from an investor to fund their cellular therapy research for certain types of cancer. The money was provided by David Jonas, the CEO of JVC Investment Partners. The research will be conducted at David and Etta Jonas Center for Cellular Therapy.

Jonas donated the money to University of Chicago specifically because of Dr. Michael Bishops work. Dr. Bishop is a Professor of Medicine at the University of Chicago and is a hematologist and oncologist. He specializes in treatments for leukemia and lymphomas and his research deals with relapse after stem cell transplantation.

RELATED:AML Relapse How IDH-Inhibitor Drugs Work To Achieve Remission Before Stem-Cell Transplant

The funding will be put towards improving stem cell therapy, like CAR-T cell therapy.

Cell therapy has been revolutionary for patients with blood cancers This has been a game changer because these are patients who wouldve inevitably died. Their average life expectancy wouldve been six months. But CAR-T cells have permitted some of these patients to achieve complete remissions, says Dr. Bishop in a Chicago Tribune article about the fund.

This fund will help more researchers join the team to better advance therapies. This grant from Jonas comes at a time when cancer research is not gaining as much funding as COVID-19 research efforts.

The Charity organization Cancer Research U.K (CRUK) announced that due to COVID-19, many research areas are not receiving as much funding. Existing grants are being cut by 10% while research centers are being cut by 20%. Overall, CRUK is looking at over $54 million being cut from their research portfolio this year.

The charity admitted toThe Daily Telegraphthat the impact of this pandemic could set back the cancer research effort within the U.K potentially for many years, but the disruption in cancer research is proving to be a world-wide issue.

Researchers told SurvivorNet that newclinical trials in the United States may be pauseddue to restrictions in place during COVID-19. With that being said, it seems that some private donors are attempting to balance out these cuts through personal donations to research groups like Jonas is doing for University of Chicago.

Learn more about SurvivorNet's rigorous medical review process.

As the coronavirus pandemic goes on, cancer researchers around the country tell SurvivorNet that they fear their funding will be diverted to research on the virus. However there are bright spots. The University of Chicago says it just received a $10 million gift from an investor to fund their cellular therapy research for certain types of cancer. The money was provided by David Jonas, the CEO of JVC Investment Partners. The research will be conducted at David and Etta Jonas Center for Cellular Therapy.

Jonas donated the money to University of Chicago specifically because of Dr. Michael Bishops work. Dr. Bishop is a Professor of Medicine at the University of Chicago and is a hematologist and oncologist. He specializes in treatments for leukemia and lymphomas and his research deals with relapse after stem cell transplantation.

The funding will be put towards improving stem cell therapy, like CAR-T cell therapy.

Cell therapy has been revolutionary for patients with blood cancers This has been a game changer because these are patients who wouldve inevitably died. Their average life expectancy wouldve been six months. But CAR-T cells have permitted some of these patients to achieve complete remissions, says Dr. Bishop in a Chicago Tribune article about the fund.

This fund will help more researchers join the team to better advance therapies. This grant from Jonas comes at a time when cancer research is not gaining as much funding as COVID-19 research efforts.

The Charity organization Cancer Research U.K (CRUK) announced that due to COVID-19, many research areas are not receiving as much funding. Existing grants are being cut by 10% while research centers are being cut by 20%. Overall, CRUK is looking at over $54 million being cut from their research portfolio this year.

The charity admitted toThe Daily Telegraphthat the impact of this pandemic could set back the cancer research effort within the U.K potentially for many years, but the disruption in cancer research is proving to be a world-wide issue.

Researchers told SurvivorNet that newclinical trials in the United States may be pauseddue to restrictions in place during COVID-19. With that being said, it seems that some private donors are attempting to balance out these cuts through personal donations to research groups like Jonas is doing for University of Chicago.

Learn more about SurvivorNet's rigorous medical review process.

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Not All Cancer Research Money Is Going Away During COVID University of Chicago Receives $10-million Gift For Cell Therapy - SurvivorNet

Scientists to study how lungs respond to worm infections – UC Riverside

A biomedical scientist at the University of California, Riverside, has received a five-year,$3.3 million grant from the National Institutes of Health, or NIH, to investigate lung immune responses to parasitic worm infections.

The research will explore how macrophages, a type of white blood cell, mediate tissue repair following infection-induced injury.

We will focus on a macrophage-secreted protein, RELMalpha, in mice and evaluate two aspects of its function in worm infection: how it regulates worm killing and how it promotes lung stem-cell growth to repair injured tissue, said Meera G. Nair, an associate professor of biomedical sciences in the School of Medicine and the grants principal investigator.

Nairs lab has generated a transgenic mouse that will allow her team to track and view the RELMalpha-expressing macrophages and also specifically delete RELMalpha in macrophages.

RELM, or resistin-like molecules, constitute a family of proteins secreted by mammals and highly expressed in infectious and inflammatory diseases. One of these proteins, RELMalpha, is quickly triggered in the mouse body following infection and serves to protect the body's tissues. Its homologue in humans, called resistin, is responsible more for protecting the body than attacking the parasite.

In collaboration with Tara M. Nordgren, an assistant professor of biomedical sciences and a lung immunologist at UC Riverside, Nair will investigate the stem cell-mediated mechanisms of lung tissue repair and the translational significance of the research teams findings by evaluating resistins effect on tissue repair in donor human tissue.

Tolerance to infections, or disease tolerance, is a mechanism used by host organisms to fight parasites or pathogens that attack the host. Nair explained that host disease tolerance is especially important in infections with macroparasites, such as helminths, that cause significant tissue damage.

Investigating these host disease tolerance mechanisms may be applicable to the treatment of tissue injury and inflammation, she said. The grant will allow us to investigate how RELMalpha contributes to host disease tolerance to helminths.

Nair and Nordgren will be joined in the research by Adler R. Dillman, an assistant professor of nematology at UCR, to investigate how RELMalpha regulates macrophage-parasite interaction and parasite development. The project will involve the participation of two postdoctoral researchers, three graduate students, and two undergraduates.

According to Nair, the teams evaluation of repair and anti-inflammatory mechanisms to promote lung tissue homeostasis may have relevance for COVID-19 infections, where severe pathological outcomes are related to excessive lung tissue damage and an inability to control the inflammatory response.

Nair has already formed partnerships with local medical centers as a result.

We soon plan to investigate if the underlying immunoregulatory mechanisms we identify in the NIH-funded project could provide insight into the pathogenesis of lung diseases such as infections due to SARS-CoV-2, the virus that causes COVID-19, specifically focusing on how COVID-19 has impacted our community in the Inland Empire, she said.

Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the NIH under Award Number R01AI153195. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Header image shows Meera G. Nair. (Carrie Rosema)

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Scientists to study how lungs respond to worm infections - UC Riverside

Global Stem Cell Therapy Market 2020: Growth, Demand, Service, Types, Applications, Key Players and Industry Forecast till 2025 – News Distinct

Global Stem Cell Therapy Market Analysis with forecast period 2020 to 2025 provides an in-depth analysis of market growth factors, future assessment, country-level analysis, Stem Cell Therapy industry distribution, and competitive landscape analysis of major industry players. The research report of global Stem Cell Therapy market report offers the extensive information about the top most makers and sellers who are doing great and are directly working right in the market now and which have great market area according to the country and region and other aspects that affect the growth of any company or industry. The report exhibits both Stem Cell Therapy market quantitative as well as qualitative data with tables and figures displayed in the form of bar graphs, and pie charts.

A leading research firm, Adroit Market Research added a latest industry report on Global Stem Cell Therapy Market consisting of 110+ pages during the forecast period and Stem Cell Therapy Market report offers a comprehensive research updates and information related to market growth, demand, opportunities in the Market.

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Global Stem Cell Therapy market study includes a thorough analysis of the overall competitive landscape and the company profiles of leading market players involved in the global Stem Cell Therapy market. Moreover, crucial specifics such as growth drivers as well as the expected growth rate of the Stem Cell Therapy market during the forecast period are included in the report. The report also details the potential growth aspects along with the restraints of this industry vertical. Further, the presented study offers accurate insights pertaining to the different segments of the global Stem Cell Therapy market such as the market share, value, revenue, and how each segment is expected to fair post the COVID-19 pandemic.

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Global Stem Cell Therapy market report estimates the revenue, industry size, types, applications, players share, production volume, and consumption to get an understanding of the demand and supply chain of the market. The report encompasses technical data, raw materials, volumes, and manufacturing analysis of the global Stem Cell Therapy market. The research study delivers future projections for prominent opportunities based on the analysis of the subdivision of the market. The study meticulously unveils the market and contains substantial details about the projections with respect to industry, remuneration forecast, sales graph, and growth prospects over the forecast timeline.

Global Stem Cell Therapy market is segmented based by type, application and region.

Based on Type, the market has been segmented into:

Based on cell source, the market has been segmented into,

Adipose Tissue-Derived Mesenchymal SCsBone Marrow-Derived Mesenchymal SCsEmbryonic SCsOther Sources

Based on application, the market has been segmented into:

Based on therapeutic application, the market has been segmented into,

Musculoskeletal DisordersWounds & InjuriesCardiovascular DiseasesGastrointestinal DiseasesImmune System DiseasesOther Applications

The market overview section highlights the Stem Cell Therapy Market definition, taxonomy, and an overview of the parent market across the globe and region wise. To provide better understanding of the global Stem Cell Therapy Market, the report includes in-depth analysis of drivers, restraints, and trends in all major regions namely, Asia Pacific, North America, Europe, Latin America and the Middle East & Africa, which influence the current market scenario and future status of the global Stem Cell Therapy Market over the forecast period.

Key Highlights Questions of Stem Cell Therapy Market:What will be the size of the global Stem Cell Therapy market in 2025?Which product is expected to show the highest market growth?Which application is projected to gain a lions share of the global Stem Cell Therapy market?Which region is foretold to create the most number of opportunities in the global Stem Cell Therapy market?Will there be any changes in market competition during the forecast period?Which are the top players currently operating in the global Stem Cell Therapy market?

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Global Stem Cell Therapy Market 2020: Growth, Demand, Service, Types, Applications, Key Players and Industry Forecast till 2025 - News Distinct

Global Stem Cells Market 2020 | Demand and Scope with Outlook, Business Strategies, Challenges and Forecasts to 2026 – Cole of Duty

Global Stem Cells Market 2020 by Manufacturers, Regions, Type and Application, Forecast to 2026 aims to target the major concepts related to market growth, major types, and various end users applicable, regional analysis, productivity structure, current market situation. The market report is a proficient and deep analysis of the present situation and challenges. The report offers analysis with regards to the past and current market situation of the global Stem Cells market. The report highlights all introducing income segmentation and also a firm sketch of the top players. It comprises streamlined financial data obtained from various research sources. The report analyzes the market players, sub-segments and sections, product category, and major improvements in the market.

Overview of The Report:

Top players are examined for revenue areas manufacturing, market rivalry, capacity, sales (value), moderate price, fabricating base supply and market share, and product types. The report also computes the limits and strong points of the players. The report studies key opportunities in the market and segmentation of market size, by volume and value, on the basis of application type and geography. The report focuses on innovative trends, implementing reasonable pricing stats in the competitive market. The overall description of the global Stem Cells market will assist our viewers to comprehend the market in the best way. It sheds light on the industry parameters by accessing the market growth, consumption volume, the upcoming market trends, and the different prices variation for the forecast year from 2020 to 2026.

NOTE: Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers post COVID-19 crisis. The report aims to provide an additional illustration of the latest scenario, economic slowdown, and COVID-19 impact on the overall industry.

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The report covers a number of the players in the market, including: CCBC, Vcanbio, Boyalife, Beikebiotech,

Segmentation by product type and analysis of the market: Umbilical Cord Blood Stem Cell, Embryonic Stem Cell, Adult Stem Cell, Other

Segmentation by application and analysis of the market: Diseases Therapy, Healthcare

The scope of the report covers market eventualities to a comparative rating between major players, price, and profit of the required market regions. This report covers North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa). It focuses on the foremost and the progressing countries from every region in detail.

The report represents the ongoing marketing trends that are faced by the market competitors, the ups, and downs in the global Stem Cells market. Subsequently, it discovers the worlds main Stem Cells industry market requirements, for example, demand, distribution, profit, production, capacity, and promote growth speed and prediction, etc. The company further divides even the economy, by state also from application/type for its landscape analysis.

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Global Stem Cells Market 2020 | Demand and Scope with Outlook, Business Strategies, Challenges and Forecasts to 2026 - Cole of Duty

Stem Cell Assay Market Growing Demand, Overview and Business Outlook to 2027 | Merck & Co., Thermo Fisher Scientific, GE Healthcare, Agilent…

Stem Cell Assay Market 2020 report covers key business segments and wide scope geographies to get deep dive analyzed industry data. The company profiles of top Market players will provide financial analysis listing the company revenue, and market share. The past and present revenue of top players will offer forecast revenue estimates and growth rates. Stem Cell Assay Market research report provide the details about industry overview and analysis about Manufacturing Cost Structure, Revenue, Gross Margin, Consumption Value, Sale Price, Major Manufacturers, Distributors with Development Trends and Forecast 2027.

The report includes the latest coverage of the impact of COVID-19 on the Stem Cell Assay industry. The incidence has affected nearly every aspect of the business domain. This study evaluates the current scenario and predicts future outcomes of the pandemic on the global economy.

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Brief Introduction to the research report.

Table of Contents (Scope covered as a part of the study)

Top players in the market

Research framework (presentation)

Research methodology adopted by CMI

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The key players profiled in this report include: Merck & Co., Thermo Fisher Scientific, GE Healthcare, Agilent Technologies, Bio-Rad Laboratories, Promega Corporation, Cell Biolabs, PerkinElmer, Miltenyi Biotec, HemoGenix, Bio-Techne Corporation, STEMCELL Technologies, and Cellular Dynamics International.

The global Stem Cell Assay market is anticipated to rise at a considerable rate during the forecast period, between 2020 and2027. In 2020, the market was growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon. The Global Stem Cell Assay market 2020 research provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Stem Cell Assay Market 2020 global industry research report is a professional and in-depth study on the Stem Cell Assay market trends, share, size, growth, as well as industry analysis.

Detailed Segmentation:

By Product Type-InstrumentsReagents & KitsBy Cell Type Adult Stem CellsInduced Pluripotent Stem CellsMesenchymal Stem CellsNeural Stem CellsHematopoietic Stem CellsUmbilical Cord Stem CellsHuman Embryonic Stem CellsBy Process Cell CultureEngineeringDifferentiationCharacterizationOthersBy Application -ResearchDrug Discovery & DevelopmentRegenerative Medicine

Regions included:

o North America (United States, Canada, and Mexico)

o Europe (Germany, France, UK, Russia, and Italy)

o Asia-Pacific (China, Japan, Korea, India, and Southeast Asia)

o South America (Brazil, Argentina, Colombia)

o Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, and South Africa)

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Research objectives

To study and analyse the global Stem Cell Assay Market Size (value and volume) by key regions/countries, product type and application, history data and forecast to 2027.

To understand the structure of Stem Cell Assay market by identifying its various sub segments.

Focuses on the key global Stem Cell Assay manufacturers, to define, describe and analyse the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

To analyse the individual Stem Cell Assay market trends, prospects, and their contribution to the total market.

To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).

To project the consumption of Stem Cell Assay submarkets, with respect to key regions (along with their respective key countries).

To analyse competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.

To strategically profile the key players and comprehensively analyse their growth strategies.

Stem Cell Assay Market report provides detailed coverage of Stem Cell Assay industry and main market trends. The Stem Cell Assay Market research includes historical and forecast market data, demand, application details, price trends, and company shares of the leading Stem Cell Assay by geography. The Stem Cell Assay Market report splits the market size, by volume and value, on the basis of application type and geography.

Important Key questions answered in Stem Cell Assay market report:

What will the market growth rate, Overview, and Analysis by Type of Stem Cell Assay market in 2027?

What are the key factors affecting market dynamics? What are the drivers, challenges, and business risks in Stem Cell Assay market?

What is Dynamics, This Overview Includes Analysis of Scope and price analysis of top Manufacturers Profiles?

Who Are Opportunities, Risk and Driving Force of Stem Cell Assay market? Knows Upstream Raw Materials Sourcing and Downstream Buyers.

Who are the key manufacturers in space? Business Overview by Type, Applications, Gross Margin, and Market Share

What are the opportunities and threats faced by manufacturers in the global market?

In the end, Stem Cell Assay Market report provides details of competitive developments such as expansions, agreements, new product launches, and acquisitions in the market for forecasting, regional demand and supply factor, investment, market dynamics including technical scenario, consumer behaviour, and end use industry trends and dynamics, capacity, spending were taken into consideration.

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Table of Contents

Report Overview: It includes the Stem Cell Assay market study scope, players covered, key market segments, market analysis by application, market analysis by type, and other chapters that give an overview of the research study.

Executive Summary: This section of the report gives information about Stem Cell Assay market trends and shares, market size analysis by region and analysis of global market size. Under market size analysis by region, analysis of market share and growth rate by region is provided.

Profiles of International Players: Here, key players of the Stem Cell Assay market are studied on the basis of gross margin, price, revenue, corporate sales, and production. This section gives a business overview of the players and shares their important company details.

Regional Study: All of the regions and countries analyzed in the Stem Cell Assay market report is studied on the basis of market size by application, the market size by product, key players, and market forecast.

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Stem Cell Assay Market Growing Demand, Overview and Business Outlook to 2027 | Merck & Co., Thermo Fisher Scientific, GE Healthcare, Agilent...

Plant Stem Cell For Cosmetics Market New Investments Expected To Boost The Demand By 2027 – News Distinct

The Latest Research Report on Global Plant Stem Cell For Cosmetics Market Update 2020 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. Providing info like market competitive situation, product scope, market overview, opportunities, driving force, and market risks. Profile the Top Key Players of Plant Stem Cell For Cosmetics, with sales, revenue, and global market share of Plant Stem Cell For Cosmetics are analyzed emphatically by landscape contrast and speak to info. Upstream raw materials and instrumentation and downstream demand analysis are additionally administrated. The Plant Stem Cell For Cosmetics market business development trends and selling channels square measure analyzed. From a global perspective, It also represents the overall industry size by analyzing qualitative insights and historical data.

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[NOTE: This report Sample includes; Brief Introduction to the research reportTable of Contents (Scope covered as a part of the study)Top players in the marketResearch framework (Structure of the actual report)The research methodology adopted by Stratagem Market Insights]

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In terms of region, this research report covers almost all the major regions across the globe such as North America, Europe, South America, the Middle East, and Africa, and the Asia Pacific. Europe and North America regions are anticipated to show an upward growth in the years to come. While Plant Stem Cell For Cosmetics Market in Asia Pacific regions is likely to show remarkable growth during the forecast period. Cutting edge technology and innovations are the most important traits of the North America region and thats the reason most of the time the US dominates the global markets. Plant Stem Cell For Cosmetics Market in the South America region is also expected to grow in the near future.

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Plant Stem Cell For Cosmetics Market New Investments Expected To Boost The Demand By 2027 - News Distinct