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Biopharma Develops Antibody and Stem Cell Therapies in the Fight Against COVID-19 – JD Supra

Updated: May 25, 2018:

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Biopharma Develops Antibody and Stem Cell Therapies in the Fight Against COVID-19 - JD Supra

University Of Miami Dr. Joshua Hare On Stem Cell Treatment – CBS Miami

CBSMiami.com Weather @ Your Desk 5-1-20 11PMCBS4 News chief meteorologist Craig Setzer's weather outlook for South Florida.

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University Of Miami Dr. Joshua Hare On Stem Cell TreatmentDr. Joshua Hare of the University of Miami Miller School of Medicine on stem cell research and treatment for COVID-19 patients.

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Baptist Hospital Patient Credits Stem Cell Treatment With Saving Her LifeThe FDA gave Baptist Health approval to test a stem-cell treatment on COVID-19 patients and so far it's come back with positive results.

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CBSMiami.com Weather @ Your Desk 5-1-20 5PMCBS4 News chief meteorologist Craig Setzer's weather outlook for South Florida.

Miami Farm Share Food Distribution Helps With Growing DemandFor many people across South Florida still out of work, it can be a struggle to put a meal on the table for their families, but food drives are helping those in need including a Farm Share food distribution held in Miami Friday morning where the need was obvious.

Miami Beach Continues Cautious ApproachOn Friday, the city of Miami Beach held a special virtual city commission meeting. Miami Beach residents were allowed to make comments or ask questions via Zoom. Many also tuned in on Facebook.

Miami-Dade Mayor Carlos Gimenez Reminds Everyone To Follow RulesMiami-Dade Mayor Carlos Gimenez is urging everyone planning to visit a park or a marina to follow the rules this weekend.

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CBSMiami.com Weather 5/1 12PMA sunny afternoon with highs near 84F.

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University Of Miami Dr. Joshua Hare On Stem Cell Treatment - CBS Miami

USC Professor Andrew P. McMahon elected to the National Academy of Sciences – USC News

Andrew P. McMahonwho is the W.M. Keck Provost and University Professor in USCs departments of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine, and Biological Sciences at the Dornsife College of Letters, Arts and Scienceshas been elected as a new member of the National Academy of Sciences in honor of his outstanding contributions to developmental biology. The National Academy of Sciences brings together nearly 3,000 leading researchers to provide objective, science-based advice on critical issues affecting the nationin accordance with an Act of Congress approved by President Abraham Lincoln in 1863.

Were delighted that Dr. McMahon is being recognized as a newly elected member of the National Academy of Sciences, said Dean Laura Mosqueda from the Keck School. Because new members are elected by current members, this represents recognition of Dr. McMahons achievements by his most esteemed peers in all scientific fields.

Being elected to the National Academy of Sciences is one of the highest honors that can be bestowed upon a scientist. Dr. McMahon has had a truly remarkable career in the field of developmental biology. This honor is well deserved. We are proud of Dr. McMahons accomplishments and of his contributions to research and education at USC, said USC Provost Charles F. Zukoski.

McMahons group is well-known for identifying key signals coordinating cell interactions directing the assembly, composition and functional organization of mammalian organ systems. This research led to the founding of a biotechnology startup and the first drug treatment for an invasive form of skin cancer.

Currently, the McMahon Lab has narrowed its focus from multiple organ systems to a single, exquisitely complex organ: the kidney. With one in 10 people worldwide affected by chronic kidney disease, McMahon has a pragmatic desire to advance stem cell research in response to this medical need.

His lab has uncovered detailed genetic and molecular clues about how developing kidneys form, as well as how adult kidneys respond to injury and disease. These discoveries inform efforts to build synthetic mini kidneys, called organoids, that can be used to study disease, identify potential drug therapies, and eventually provide functional tissue for transplantation.

McMahon laid the groundwork for his career in developmental biology when he was still a high school student in the United Kingdom, studying for his university entrance exams.

The great thing about sitting the exam for Oxford University was that it excused me from taking the regular classes at school and allowed me to just read things that I thought were interesting, he said. So I started reading books about how our genes worked.

During his undergraduate studies at Oxford University, McMahon became fascinated by how genes orchestrated the intricate process of human embryonic development.

Im always looking for answers to what I consider to be the most interesting question of all, said McMahon. How do our genes direct one cell, the egg, to generate the remarkable diversity of different cell types in our bodies?

He continued this line of inquiry during his PhD studies at University College London, and his postdoctoral training at the California Institute of Technology. He started his independent research career at the National Institute for Medical Research in London, then moved to the Roche Institute for Molecular Biology, before joining the faculty at Harvard University in 1993.

After a nearly 20-year career at Harvard, McMahon joined USC as the Director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research in 2012. He established a new Department of Stem Cell Biology and Regenerative Medicine, which he chairs, and recruited a large cohort of early-career scientists at the start of their faculty careers.

In addition to his most recent accolade from the National Academy of Sciences, McMahon is an elected fellow of the American Association for the Advancement of Science, the American Academy of Arts and Sciences, the European Molecular Biology Organization, and the Royal Society.

His group has published more than 300 primary research articles, and 22 US patents and 30 foreign patents have been issued around his research.

It may be a clich, but its true: this recognition is really a recognition of the many talented students, postdoctoral fellows and research staff I have been privileged to work with at several institutions throughout my career, said McMahon. I am glad my good fortune continues at USC.

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USC Professor Andrew P. McMahon elected to the National Academy of Sciences - USC News

AgeX Therapeutics Announces Reduction in Projected Cash Expenditures – BioSpace

AgeX plans to continue to pursue its licensing and collaboration strategy for its two primary technology platforms, UniverCyte immunotolerance technology, and PureStem cell derivation and manufacturing technology. Since the launch of its licensing and collaboration strategy in January 2020, AgeX delivered a research collaboration in Japan focused on developing universally transplantable cells for therapeutic use based on UniverCyte, and entered into a neural stem cell therapy research collaboration for neurological disorders utilizing PureStem at a California state university. AgeXs budgetary and personnel adjustments will result in the deferral of in-house work on the development of AgeX therapy product candidates, including AGEX-VASC1 and AGEX-BAT1, and its induced tissue regeneration (iTR) technology, and may also lead to outsourcing of some of that work, until further funding can be obtained to rebuild a research and development staff for one or more of those programs. Development of AgeXs iTR technology may be done at AgeXs subsidiary Reverse Bioengineering, Inc. subject to successful financing of the subsidiary.

About AgeX Therapeutics

AgeX Therapeutics, Inc. (NYSE American: AGE) is focused on developing and commercializing innovative therapeutics for human aging. Its PureStem and UniverCyte manufacturing and immunotolerance technologies are designed to work together to generate highly defined, universal, allogeneic, off-the-shelf pluripotent stem cell-derived young cells of any type for application in a variety of diseases with a high unmet medical need. AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes. AgeXs revolutionary longevity platform induced Tissue Regeneration (iTR) aims to unlock cellular immortality and regenerative capacity to reverse age-related changes within tissues. AGEX-iTR1547 is an iTR-based formulation in preclinical development. HyStem is AgeXs delivery technology to stably engraft PureStem cell therapies in the body. AgeX is developing its core product pipeline for use in the clinic to extend human healthspan, and is seeking opportunities to establish licensing and collaboration arrangements around its broad IP estate and proprietary technology platforms.

For more information, please visit http://www.agexinc.com or connect with the company on Twitter, LinkedIn, Facebook, and YouTube.

Forward-Looking Statements

Certain statements contained in this release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not historical fact including, but not limited to statements that contain words such as will, believes, plans, anticipates, expects, estimates should also be considered forward-looking statements. Forward-looking statements involve risks and uncertainties. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the business of AgeX Therapeutics, Inc. and its subsidiaries, particularly those mentioned in the cautionary statements found in more detail in the Risk Factors section of AgeXs most recent Annual Report on Form 10-K filed with the Securities and Exchange Commissions (copies of which may be obtained at http://www.sec.gov). Subsequent events and developments may cause these forward-looking statements to change. AgeX specifically disclaims any obligation or intention to update or revise these forward-looking statements as a result of changed events or circumstances that occur after the date of this release, except as required by applicable law.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200501005295/en/

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AgeX Therapeutics Announces Reduction in Projected Cash Expenditures - BioSpace

Big Boom in Stem Cell Antibody Market with a Growing CAGR During 2020-2027 | Rising Growth by Top Players- Thermo Fisher Scientific, Merck Group,…

The report titled, Stem Cell Antibody Market boons an in-depth synopsis of the competitive landscape of the market globally, thus helping establishments understand the primary threats and prospects that vendors in the market are dealt with. It also incorporates thorough business profiles of some of the prime vendors in the market. The report includes vast data relating to the recent discovery and technological expansions perceived in the market, wide-ranging with an examination of the impact of these intrusions on the markets future development.

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Big Boom in Stem Cell Antibody Market with a Growing CAGR During 2020-2027 | Rising Growth by Top Players- Thermo Fisher Scientific, Merck Group,...

Stem Cell Therapy Market Growth Opportunities, Challenges, Key Companies, Drivers and Forecast to 2026 Cole Reports – Cole of Duty

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Stem Cell Therapy Market Growth Opportunities, Challenges, Key Companies, Drivers and Forecast to 2026 Cole Reports - Cole of Duty

Exclusive Interview with Renowned Coronavirus Researcher Dr. Camillo Ricordi – The Jewish Voice

by Lieba Nesis

Having the opportunity to speak with Dr. Camillo Ricordi, one of the foremost experts on stem cell research, was nothing short of extraordinary. The 63-year-old scientist is director of the Diabetes Research Institute at the University of Miami. While his specialty is pancreatic islet transplantation for Type 1 Diabetes, when coronavirus came calling he sprung into action. Since January he has been working 16 hours a day 7 days a week to help his colleagues in China, Italy and the US battle the deadly affliction. He is now conducting a clinical trial with 24 patients to test the efficacy of stem cells in critically ill COVID-19 patients. The cells which are injected directly into the lung hone in on the injury and inflammation producing an army of 200 million cells to fight the complications of the illness. Here are excerpts of my conversation with this heroic doctor who is on the front lines of this drudgerous battle.

I began by asking Ricordi if he was caught unawares by the virus: to which he responded there were simulations and warnings from individuals such as Bill Gates since 2014. However, he acknowledged until you get hit you dont think its real. Ricordi believes the virus emanated from a Wuhan lab which the NY Post and Newsweek claim was financially backed by the NIH, the CDC and the WHO, with Dr. Fauci contributing $7.4 million to the Wuhan Virology Lab. Ricordi cited the position of 200 scientists who had expressed concern of potentiating virus research in bats due to the possibility of a catastrophic leak. Ricordi is in agreement with Nobel Prize Winner Luc Montagniers assertion that the virus was engineered by inserting genes from HIV into the coronavirus in a misfired bid to find an AIDS vaccine. The bat which has a high number and rate of virus mutations was the perfect medium for creating a marginally lethal, yet highly contagious disease. With the viruses high level of changeability Ricordi was dubious as to whether the precise source of origination would ever be discovered. He also expressed concern as to the efficacy of a vaccine, since it might protect against COVID-19 but be ineffectual when a different strain called COVID-20 and 21 appeared.

One of the tricks to fighting this disease is building a strong immune system through an anti-inflammatory diet and supplements such as Vitamin C, D, Omega 3, Zinc and Resveratrol, according to Ricordi. While he is optimistic the disease will diminish during the summer months, he is equally confident a second and stronger wave will hit in the winter if lockdown procedures are relaxed-akin to what has occurred in Japan where a second state of emergency was declared on April 6th. Ricordi mentioned that China destroyed a paper proving the virus was engineered replacing it with documentation confirming natural origin leading him to conclude the disease was in fact manipulated. Ricordi is of the opinion that a cocktail will eventually be used to successfully treat the disease. Remdesivir and Hydroxychloroquine, he conceded, show immense promise if used in correct dosages and at the incipient stages of the illness before the patient becomes critically ill.

Ricordi is the most often quoted expert on stem cell research where he has successfully prevented the acceleration of aging as well as kidney and eye disease in patients with Type 1 diabetes. He has currently diverted a number of resources from diabetes to the study of COVID-19 where he has injected his 4th critically ill COVID patient with stem cells in a double blind study-the results of which will be ready in two months. The cells which were retrieved from the placenta of a baby can be used to treat more than 10,000 patients. The injections are administered intravenously with the natural first filter being the targeted area of the lungs (unlike in diabetes where a catheter has to be inserted to ensure cell transmission to the pancreas) The FDA approved his trial in a record weeks time and the 24 critically ill patients who receive the cells should see effects in weeks. Ricordis optimism is backed by science since colleagues in Israel reported zero deaths after using stem cells in 6 critically ill coronavirus patients. China had similarly favorable outcomes with no deaths in 80 seriously ill patients. Furthermore, injecting the cells is a benign procedure that takes only 10 to 15 minutes to perform. Unlike other treatments, the availability of cells abound with more than 3.8 million births in the US last year providing viable placentas. Moreover, the benefits of building a large scale emergency response repository in the form of cell banks to treat Alzheimers, severe lung damage, diabetes, and kidney disease in between pandemics would be revolutionary.

Stem cells have not been heretofore utilized due to the FDAs stringent safety requirements. Furthermore, there are significant costs associated with clinical trials where environmental sterility and quality control are carefully monitored. Ricordi raised funds from private individuals-90 percent of whom were of Italian descent. In his next larger trial he will be addressing how to stop progression of the disease in less severe cases. Ricordi stressed the importance of wearing masks and socially distancing due to the viruses airborne nature; noting that contained spaces such as cruise ships, planes, hospitals and nursing homes were especially problematic. Ricordi is currently meeting with architects to discuss how to construct pandemic resistant buildings which use ultraviolet lights in bathrooms and avoid recycled air. Our entire future will be reinvented said Ricordi, as telemedicine and home monitoring of patients will soon become commonplace. He also predicted there will be future pandemics as the distance between animals and humans continues to narrow with monkeys and bats encroaching on human habitats and vice versa-due to limited space. Moreover, Ricordi remarked bioweapons and vaccines were a disaster waiting to happen. As Ricordi rushed to attend a pivotal meeting he casually mentioned his daughter was working as an ICU nurse in California-another reason this heroic warrior felt such an urgent calling to discover an imminent cure.

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Exclusive Interview with Renowned Coronavirus Researcher Dr. Camillo Ricordi - The Jewish Voice

Increasing Demand For Induced Pluripotent Stem Cell Market To Substantially Surge The Revenues Through The COVID-19 Lockdown Phase – Jewish Life News

A recent market study on the global Induced Pluripotent Stem Cell market reveals that the global Induced Pluripotent Stem Cell market is expected to reach a value of ~US$ XX by the end of 2029 growing at a CAGR of ~XX% during the forecast period (2019-2029). The impact of the COVID-19 pandemic on the global Induced Pluripotent Stem Cell market is discussed in the presented study.

The Induced Pluripotent Stem Cell market study encloses a thorough analysis of the overall competitive landscape and the company profiles of leading market players involved in the global Induced Pluripotent Stem Cell market. Further, the presented study offers accurate insights pertaining to the different segments of the global Induced Pluripotent Stem Cell market such as the market share, value, revenue, and more.

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The presented report segregates the Induced Pluripotent Stem Cell market into different segments to ensure the readers gain a complete understanding of the different aspects of the Induced Pluripotent Stem Cell market.

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Segmentation of the Induced Pluripotent Stem Cell market

Competitive Outlook

This section of the report throws light on the recent mergers, collaborations, partnerships, and research and development activities within the Induced Pluripotent Stem Cell market on a global scale. Further, a detailed assessment of the pricing, marketing, and product development strategies adopted by leading market players is included in the Induced Pluripotent Stem Cell market report.

Market Taxonomy

The global iPS cell market has been segmented into:

Cell Type

Application

End User

Region

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Increasing Demand For Induced Pluripotent Stem Cell Market To Substantially Surge The Revenues Through The COVID-19 Lockdown Phase - Jewish Life News

Stem Cell Alopecia Treatment Market Growth Opportunities, Challenges, Key Companies, Drivers and Forecast to 2026 Cole Reports – Cole of Duty

Sanford Burnham Prebys Medical Discovery Institute

Global Stem Cell Alopecia Treatment Market: Competitive Landscape

This section of the report lists various major manufacturers in the market. The competitive analysis helps the reader understand the strategies and collaborations that players focus on in order to survive in the market. The reader can identify the players fingerprints by knowing the companys total sales, the companys total price, and its production by company over the 2020-2026 forecast period.

Global Stem Cell Alopecia Treatment Market: Regional Analysis

The report provides a thorough assessment of the growth and other aspects of the Stem Cell Alopecia Treatment market in key regions, including the United States, Canada, Italy, Russia, China, Japan, Germany, and the United Kingdom United Kingdom, South Korea, France, Taiwan, Southeast Asia, Mexico, India and Brazil, etc. The main regions covered by the report are North America, Europe, the Asia-Pacific region and Latin America.

The Stem Cell Alopecia Treatment market report was prepared after various factors determining regional growth, such as the economic, environmental, technological, social and political status of the region concerned, were observed and examined. The analysts examined sales, production, and manufacturer data for each region. This section analyzes sales and volume by region for the forecast period from 2020 to 2026. These analyzes help the reader understand the potential value of investments in a particular country / region.

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The report provides an in-depth analysis of the size of the Stem Cell Alopecia Treatment world market, as well as recent trends and future estimates, in order to clarify the upcoming investment pockets.

The report provides data on key growth drivers, constraints and opportunities, as well as their impact assessment on the size of the Stem Cell Alopecia Treatment market.

Porters 5 Strength Rating shows how effective buyers and suppliers are in the industry.

The quantitative analysis of the Stem Cell Alopecia Treatment world industry from 2020 to 2026 is provided to determine the potential of the Stem Cell Alopecia Treatment market.

This Stem Cell Alopecia Treatment Market Report Answers To Your Following Questions:

Who are the main global players in this Stem Cell Alopecia Treatment market? What is the profile of your company, its product information, its contact details?

What was the status of the global market? What was the capacity, the production value, the cost and the profit of the market?

What are the forecasts of the global industry taking into account the capacity, the production and the value of production? How high is the cost and profit estimate? What will be the market share, supply, and consumption? What about imports and export?

What is market chain analysis by upstream raw materials and downstream industry?

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Tags: Stem Cell Alopecia Treatment Market Size, Stem Cell Alopecia Treatment Market Trends, Stem Cell Alopecia Treatment Market Growth, Stem Cell Alopecia Treatment Market Forecast, Stem Cell Alopecia Treatment Market Analysis

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Stem Cell Alopecia Treatment Market Growth Opportunities, Challenges, Key Companies, Drivers and Forecast to 2026 Cole Reports - Cole of Duty

Stem Cell Therapy: A Ray of Hope to End Global Pandemic of COVID-19 – Communal News

I would never have thought that a mutant flu virus could create that big panic in people at each and every corner of the world. In fact, the past few days in quarantine have really made me realize where exactly humanity is heading. For the majority of us, our lives are on a temporary hold while the world is dealing with the global pandemic of COVID-19.

In fact, the past three months have served as something of inflection for many countries and as the number of infected patients has surpassed onemillion, there is already a sense of worry looming across the industries. Since Coronavirus is a newly identified pathogen, there is no known pre-existing immunity observed in humans and therefore everyone is assumed to be susceptible.

While researchers all across the globe are putting efforts to develop an immediate treatment, there are speculations, based on credible evidence, that infected patients treated with Stem Cell Therapy are more likely tosurvive the disease. Specifically, mesenchymal stem cells can be effectively used to improve patients resistance to the SARS-CoV-2 virus-induced pneumonia as these cells have the potential to repair damaged tissues in the patients respiratory system leading to a speedy recovery.

Recent Trends

Looking at the efforts made by different pharmaceutical companies, I felt assured and hopeful as many patients have successfullyrecovered, while others are on the verge of getting discharged by using these novel classes of regenerative medicines.

What are the Key Hubs for Stem Cell Research?

With the virus strengthening its foothold in several countries across the globe, the threat of pandemic has become real and the question is are we ready?

As per the recent study published byRoots Analysis, the efforts for the development of stem cell therapies have been undertaken by players all across the globe, majority of the developers (45%) are based in Asia-Pacific regions; China, South Korea and Japan; followed by developed countries, such as the US, Germany, Belgium, Spain and the UK.

Roots Analysis, in its recent report, has captured the clinical and research landscape of stem cell therapy-based treatment. To know further, check out the report here.

Expert Opinion

In fact. several industry stakeholders are quite optimistic about the future market potential of stem cell-based therapies.

Bottom Line: Stay Cautious, Stay Hopeful!!

In the midst of the anxiety, worry, and uncertainty surrounding the COVID-19 pandemic, each day seems to bring news thats worse than the day before. However, remember this is not for the first time any pandemic outbreak has taken place in the history of mankind. About 200,000 (~20%) patients have already beenrecoveredfrom this disease. The sky is not falling and for sure, life would return to normal. Stay cautious, stay hopeful.

For further information check out the report here.

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Stem Cell Therapy: A Ray of Hope to End Global Pandemic of COVID-19 - Communal News