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Global Cell Sorting Market 2020 Industry Analysis by Manufacturers, Type, Application, End-User and Forecast 2025 – Bandera County Courier

A new research study titled Global Cell Sorting Market Report 2020, Forecast to 2025 has been presented by Magnifier Research which offers a comprehensive analysis on the market. Users can benefit from this complete market research report with all the required useful information about this market. The report covers the important components related to the top sellers of the global Cell Sorting industry that influence the market. However, it inspects the primary formats changing the dynamics of the market. Likewise, it covers related current affairs, which will be influencing the market. What more, it simplifies the essential sections and also the sub-sections that represents the recent zone.

Key Components Covered in The Report:

The research document is a detailed study on the growth, investment opportunities, market statistics, growing competition analysis, major key players, industry facts, important figures, sales, prices, revenues, gross margins, market shares, business strategies, top regions, demand, and developments. The report further estimates the global Cell Sorting industry esteem chain, powerful business strategies, cost, structure, creation limit, conveyance, market range, and limits usage rate. The market provides basic information of market members and organizing profiling, contact data, item/benefit beds, income development, revenue generation, and gross deals. This study also provides sales, revenue, and market share for each player covered in this report for a period between 2015 and 2020.

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Following are the topmost key players covered in this global Cell Sorting market research report:- NanoCellect Biomedical, Innovative Biochips, Cesca Therapeutics, Fluidigm, LumaCyte, Union Biometrica, LevitasBio, RareCyte, Cytonome, Namocell, STEMCELL Technologies, Akadeum Life Sciences

Together with geography at the worldwide forecast to 2025 is just absolutely professional and thorough. Moreover, the research study lists the major regional countries, focusing on the remarkable regions:- North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa).

The market segment based on product type includes:- Cancer Cell, Immune Cells, Microbial Cell, Red Blood Cell/Platelet, Stem Cell, Other

Applications mentioned in this report:- Cell Research, Biomedical Diagnosis, Other

Furthermore, the global Cell Sorting market has been divided into types, applications, and regions. This data provides a detailed and accurate country-wise volume analysis and region-wise market size analysis of the global market. The report further includes market shares for 2015 and 2025, for each of the above-mentioned segments. It also highlights the export and import of the market. It also analyses the regional distribution of the industry in terms of development trends.

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Magnifier Research is a leading market intelligence company that sells reports of top publishers in the technology industry. Our extensive research reports cover detailed market assessments that include major technological improvements in the industry. Magnifier Research also specializes in analyzing hi-tech systems and current processing systems in its expertise. We have a team of experts that compile precise research reports and actively advise top companies to improve their existing processes. Our experts have extensive experience in the topics that they cover. Magnifier Research provides you the full spectrum of services related to market research, and corroborate with the clients to increase the revenue stream, and address process gaps.

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Global Cell Sorting Market 2020 Industry Analysis by Manufacturers, Type, Application, End-User and Forecast 2025 - Bandera County Courier

Synthetic Stem Cells Market research by Growth, Competitive methods and Forecast to 2026 – Latest Herald

Synthetic Stem Cells Market research report enhanced worldwide COVID19 Impact analysis on Market Size (Value, Production, Sales, Consumption, Revenue, and Growth Rate), Gross Margin, Industry Chain, Trends, Top Manufacturers, Development Trends, History and 6 Year Forecast. This Synthetic Stem Cells Market competitive landscapes provides details by topmost manufactures like (North Carolina State University, Zhengzhou University) with data such as Company Profiles, Trade Sales Volume, Gross, Cost, Industry Share By Type, Product Revenue , Specifications and Contact Information. Besides, Synthetic Stem Cells industry report helps to analyse competitive developments such as Joint Ventures, Strategic Alliances, Mergers and Acquisitions, New Product Developments, Research and Developments.

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Target Audience of the Synthetic Stem Cells Market in This Study: Key Consulting Companies & Advisors, Large, medium-sized, and small enterprises, Venture capitalists, Value-Added Resellers (VARs), Manufacturers, Third-party knowledge providers, Equipment Suppliers/ Buyers, Synthetic Stem Cells market Investors/Investment Bankers, Research Professionals, Emerging Companies, Service Providers.

Scope of Synthetic Stem Cells Market:Synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies. Additionally, these cells have better preservation stability and the technology is generalizable to other types of stem cells.

On the basis of product type, this report displays the shipments, revenue (Million USD), price, and market share and growth rate of each type.

Cardiovascular Diseases Neurological Disorders Other Diseases

On the basis on the end users/applications,this report focuses on the status and outlook for major applications/end users, shipments, revenue (Million USD), price, and market share and growth rate foreach application.

Cancers Wounds and Injuries Musculoskeletal Disorders Blood disorders

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Geographically, the report includes the research on production, consumption, revenue, Synthetic Stem Cells market share and growth rate, and forecast (2020-2026) of the following regions:

Key Developments in the Synthetic Stem Cells Market:

To describe Synthetic Stem Cells Introduction, product type and application, market overview, market analysis by countries, Synthetic Stem Cells market Opportunities, Market Risk, Market Driving Force;

To analyze the manufacturers of Synthetic Stem Cells market , with Profile, Main Business, News, Sales, Price, Revenue and Market Share in 2016 and 2020;

To display the competitive situation among the top manufacturers in Global, with sales, revenue and Synthetic Stem Cells market share in 2016 and 2020;

To analyze the key countries by manufacturers, Type and Application, covering North America, Europe, Asia Pacific, Middle-East and South America, with sales, revenue and Synthetic Stem Cells market share by manufacturers, types and applications;

To analyze the Synthetic Stem Cells market Manufacturing Cost, Key Raw Materials and Manufacturing Process etc.

To analyze the Industrial Chain, Sourcing Strategy and Downstream End Users (buyers);

To describe Synthetic Stem Cells market sales Channel, Distributors, Traders, Dealers etc.

To describe Synthetic Stem Cells market Research Findings and Conclusion, Appendix, Methodology and Data Source.

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Synthetic Stem Cells Market research by Growth, Competitive methods and Forecast to 2026 - Latest Herald

Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market 2020 Industry Size, Growth, Revenue, Global Statistics and Forecast to 2026 – Cole…

Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Report covers the Size, share, Growth Industry preparation models, producing method, situation and business operations of this Market. Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market industry report 2020-2026 report covers the most recent development establishing in the Market, development opportunities and situation.

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The report offers clearing sections of insights extracted by completely breaking down authentic and current improvements in the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market. It additionally gives second to none cutting edge estimations to different essential elements including Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market size, share, net profit, sales, revenue, and growth rate.

The key players covered in this study

The key players covered in this studyOrange County Hair Restoration CenterHair Sciences Center of ColoradoAnderson Center for HairEvolution Hair Loss InstituteSavola Aesthetic Dermatology CenterVirginia Surgical CenterHair Transplant Institute of MiamiColorado Surgical Center & Hair Institute

Key Points Describing Various Key Points:-

Manufacturing Analysis The Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market gives a section featuring manufacturing process investigation approved by means of essential data gathered through Industry specialists and Key authorities of profiled organizations.

Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Competition Leading professionals have been investigated depending on their company profile, product database, capacity, product/service value, transactions, and cost/revenue.

Demand & Supply and Effectiveness Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies report additionally provides distribution, Production, Consumption & EXIM (Export & Import).

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The Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Report covers an analytical view with complete information on product representations, sales, and revenue by sector, including manufacturing cost breakdown, industrial chain, market effect factors. The Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market size will grow from USD in 2020 to USD by 2026, at estimated CAGR values.

The Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies has been observing an impressive change in its size and value. The report introduces a detailed examination of the different segments and sub-sections of the market, including the product types, advancements, applications, industry verticals, and areas that are relied upon to command the Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market during the estimated forecast period.

Key Focused Regions in the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market:

South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market (Brazil, Argentina)

The Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market (South Africa, Saudi Arabia)

Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market (Spain, U.K., Italy, Germany, Russia, France)

North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market (U.S., Mexico, Canada)

Asia-Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market (China, Japan, India, Southeast Asia)

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Table of Contents Describing Detail Research Report:

1 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Overview

2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Competition by Manufacturers

3 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Retrospective Market Scenario by Region

4 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Historic Market Analysis by Type

5 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Historic Market Analysis by Application

6 Company Profiles and Key Figures in Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Business

7 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Manufacturing Cost Analysis

8 Marketing Channel, Distributors and Customers

9 Market Dynamics

10 Global Market Forecast

11 Research Finding and Conclusion

12 Methodology and Data Source

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Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market 2020 Industry Size, Growth, Revenue, Global Statistics and Forecast to 2026 - Cole...

How firms respond to opportunities created by pandemic will say a lot about their corporate cultures – NutraIngredients-usa.com

First off, a caveat: To say companies are profiting from the crisis sounds overly harsh, and is not meant to be so. But there has been a lot of in crisis opportunity like statements being made. And one of these opportunities is the opportunity to make money.

Any business that aims to operate for long has to turn a profit, and preferably every year. And even a company that be cast as cynically making hay while the pandemic sun shines is still keeping people employed, which is an important service in and of itself in this time of unprecedented job losses. Surviving this year is going to be a grave challenge for many firms, and the more that can stay in business, the better.

Certainly there are cynical profiteers on display. The Federal Trade Commission just announced a further 21 warning letters sent out to companies making improper disease claims. These run the gamut from dietary supplement companies, to those advocating injections of Vitamin C to stem cell clinics. One thing that unites them all in FTCs view: They do not have adequate research to back their findings. According the US Food and Drug Administration, there is to date no approved treatment for COVID-19.

Some industry stakeholders have moved to try to reign in potential excesses. The Global Organization for EPA and DHA Omega-3s (GOED) for example has warned members against making immunity claims connected to omega-3s. Any such claim in the current climate could be implied as COVID-19 treatment claim, and the trade group believes there is insufficient evidence to support either positive general or viral immunity outcomes in a healthy population.

Other immune health claims have abounded. Vitamin C and elderberry products have been flying off the shelves to the point that supplies have gotten very short, and astragalus and echinacea products are in high demand, too. I dont doubt the people marketing many of these products honestly believe in their benefits, and argue that having an immune system loaded with all of the tools it needs to perform at peak efficiency is the best way to go during these pandemic times. You do get the feeling, though, that if some consumers misunderstand and believe these products will actually help fight the virus directly, well, thats something theyre willing to live with.

Interestingly, a couple of companies that have dietary supplement ingredients that have actual, direct immune health data, Kerry with its Wellmune product and Embria Health Sciences (Cargill) with its EpiCor ingredient, have steered clear of any COVID-19 tie-ins. In a section on the virus on its website, Kerry merely says this: We remain committed to providing the best possible immune health ingredient through our dedication to safety, efficacy and scientific research. No nudge-nudge, wink-wink type statements like: We cant treat COVID-19, BUT . . . Embria has chosen to avoid mentioning COVID-19 altogether.

Some companies have chosen to be of service in other ways. Several manufactures of CBD ingredients, companies that have existing large ethanol supply chains for their primary hemp extractions, have opted to apply for rapid OTC approval to transition into hand sanitizer production. In this way they are meeting a critical need in the marketplace while also bolstering their own operations.

There has been some question in the CBD markets about a mismatch between extraction capacity and demand. While demand for the existing consumer products has held steady, because the federal regulatory logjam on the ingredient seems to have stalled, big CPG players have held back in launching SKUs containing hemp extracts. This has left some of these companies holding the bag for big investments made to meet a demand which has not yet materialized. Making hand sanitizer could be a way to make use of equipment, keep workers on the job and help the broader community while trying to weather this particular storm.

Other companies in the dietary supplements and functional foods industries have worked to help people impacted by the crisis directly. Companies like Modere and Liquid I.V. have donated products to first responders and doTerra has launched a fund raising drive to raise money for personal protective equipment purchases for health care workers.

Companies will find a variety of ways to respond to this crisis, and how they go about capitalizing on these opportunities will say a lot about their corporate cultures.

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How firms respond to opportunities created by pandemic will say a lot about their corporate cultures - NutraIngredients-usa.com

The Dermatologist Whos Obsessed With Sun Damage – The Cut

Photo: Courtesy of the Laser & Skin Surgery Center of New York

Dermatologist Robert Anolik treats some of New Yorks most discerning faces his clients include Stephanie Seymour and Kelly Ripa but that doesnt stop him from worrying about fictional characters, too. Over the past few weeks, he, his wife, and their 7- and 5-year-old kids have been watching The Singing Detective, an 80s-era BBC show about a hospitalized mystery writer.

It has great music in it, but my kids keep asking me all these questions about the main character, whos covered in psoriasis and has psoriatic arthritis, says Anolik, a dermatologist at the Laser & Skin Surgery Center of New York. All I can think about is how that patient could be helped dramatically today with the approach of medical dermatology.

Anolik was a protege of the late Dr. Fredric Brandt, who was well-known in the beauty world for popularizing Botox. But what initially drew him to cosmetic dermatology wasnt injections or chemical peels, but DNA, RNA, and proteins. As a molecular biology major at Princeton, he spent one summer at the Institute for Genomic Research, studying the science of sequencing the human genome. In medical school, I saw how protein sequence analysis touched every field in medicine, but particularly skin and aging, he says. I approach skin with that kind of molecular framework to make it healthy and beautiful.

During his dermatological training at NYU, Anolik landed a fellowship with famed dermatologist Roy Geronemus, director of the Laser & Skin Surgery Center. Brandt was also part of the practice, and when he wanted to divide his time more evenly between his Miami and New York practices, Anolik became his official associate.

He wanted someone who also had laser expertise, which he knew I had, says Anolik. Even though we looked like total opposites, our personalities clicked.

Five years later, tragedy struck and Brandt took his own life. Anolik seamlessly took over, with high-profile clients now trusting their complexions to him.

These days, until he can see those patients again, hes been volunteering at Bellevue Medical Center, tending to patients with post-op wounds and other surgery-related issues. Stuff that needs attention by a physician, he says. Theyre all so overwhelmed, so hopefully I can help decrease the burden.

Anolik spoke with the Cut about the calming presence of Angela Lansbury, his complicated relationship with fruit, and why now is the perfect time to exfoliate.

Whats your definition of beauty? The Keats line beauty is truth; truth beauty is a chestnut for a reason. When I look at a face, my goal is to reveal its truth, that is to let its beauty become manifest, which is why I work very hard to eliminate distortions, both external (e.g., sun damage) and internal (e.g., psychological negativity).

What do you think of when you hear the term clean beauty? I get wary when I hear it. I believe in the sentiment that drives the clean beauty concept. As a scientist, however, I also believe in rigorous study over intuition and guesswork. Just because something grows on a tree doesnt mean its safe and/or effective. And even the cleanest ingredients in too high a quantity can be dangerous. For example, drinking too much water will kill us. And, conversely, an ingredient that sounds strange or worrisomely artificial can, in fact, be beneficial. A word of caution for those experimenting with only clean or alternative therapies: If you believe something is strong enough to help you, its likely strong enough to hurt you as well. So dont overdo it! And be sure to consult with a board-certified dermatologist about safe strategies.

Where, if anywhere, in your beauty (or life) routine are you not quitethat clean, green, or sustainable? I drink diet soda. Its dumb and I know better, but I do it anyway.

Please fill in the blank as it pertains to beauty or wellness: I think about ______a lot. SUN DAMAGE.

What is the opposite of beautiful? An artificial appearance. Lips that are too big or faces that are frozen are not beautiful. And believe me, I cringe more than you do when its obvious someone has had work done. Just because we can do something in cosmetic dermatology, doesnt mean we should.

What is your morning skin-care routine? Alastin Gentle Cleanser or Neutrogena Ultra Gentle Cleanser, shave, sulfacetamide wash to reduce shave irritation, LaRoche-Posay Anthelios Melt-In Sunscreen Milk SPF 60, SkinMedica HA5 Rejuvenating Hydrator.

Whats the last product you use every night? A prescription retinoid, then moisturizer. Usually Alastin Ultra-Nourishing Moisturizer or Cerave Cream.

Who cuts your hair? Garren. Asking Garren to cut my hair is like asking van Gogh to paint on a milk carton. But hes my friend; he pretends not to mind.

Toothbrush of choice: My wife bought me a Sonicare but I still use the freebie from the dentist.

Razor of choice: Gilette Fusion 5.

Shaving cream of choice: Gillette Fusion Hydra Shave Gel Ultra-Sensitive.

Hand wash of choice: Dove Foaming Hand Wash.

Hand sanitizer of choice: Purell.

Fragrance of choice: Hermes Eau dorange verte Eau de cologne.

Bath or shower: Shower, with Olay Ultra Moisture Body Wash with Shea Butter, R&Co. Television Shampoo, Television Conditioner, and Acid Wash.

What was your first grooming product obsession? In third grade, I discovered mousse. Id blow-dry my hair with it. Maybe I watched St. Elmos Fire a few too many times.

Daily carry-all of choice: Prada nylon shoulder bag. A gift from Dr. Brandt. Prada was a favorite brand of his.

What do you splurge on? My wifes very particular about our sons footwear. Lots of tiny pairs of Air Jordans, Converse, Vans, and Adidas Gazelles by our front door.

What is your classic uniform (under your lab coat)? Black or navy Brooks Brothers pants and black or navy Ralph Lauren crew neck sweater.

Whose shoes are you usually wearing? Greats Royale sneakers.

What do you own too many of? Medical journals. I know at this point that the past issues are all online where I read the new ones, but theres something enjoyable about referencing them with your handwritten notes. At some point, theyll find their way to the recycling bin.

Any secret talent or skill you possess? I can juggle.

What is your own personal definition of misery? Fruit of any kind in my desserts. I love cake but Im crushed when it turns out to be carrot, and I cannot get enough ice cream but I pout when the flavor turns out to be strawberry.

What is your own personal definition of glee? Getting my cholesterol tested. I dont eat all that well, and Im not great about exercising, but my cholesterol is always low. I find that so gratifying.

Favorite way or place to spend a weekend? Nantucket. My wifes family has a house there, and they make fun of me when I wear my aqua socks to the beach.

What do you most often disagree with others about? People who insist they need to get a base tan before a tropical vacation. This is nuts. You should avoid getting a tan before your tropical vacation and during your tropical vacation and after your tropical vacation. Heres what you should get instead: sunscreen and sun-protective clothing.

What must you adjust or fix when you see it done incorrectly? Bad Botox on someone who comes in for a first-time consultation.

Favorite CBD product: Ridgway Hemp Love Balms.

What calms you down? Seinfeld reruns on Netflix. And when Im really feeling stressed: Murder, She Wrote reruns on Amazon Prime (dont judge).

Comfort food: Oreos and milk.

Vice snack: Chili-roasted pistachios and Empire Bakery house-made Twinkies.

What do you foresee as the top beauty and wellness trends for 2020? Combination therapy, specifically more one-day treatments that combine multiple lasers and injections. We have been developing this for years and are now presenting safety data on the subject.Also, laser-assisted drug therapy, such as resurfacing lasers followed by topical applications of skin-brightener serums and platelet-rich plasma. Heres what I hope is the top beauty/wellness trend in 2020: a public repudiation of non-board-certified dermatologists performing cosmetic dermatology procedures on people.

What treatment at your practice is misunderstood and should be morepopular? Laser resurfacing. Granted, this is already a very popular treatment in our office, but I believe it should be even more popular. Somepatients come in with misinformation that laser resurfacing thins theskin. Nothing could be further from the truth. In fact, it does theopposite. It targets collagen-producing cells in the dermis andgenerates a stronger, more resilient skin.

What treatment is currently your favorite (understanding that thiscould change all the time)? Botox. And it has been for years. Precise treatment avoids artificial outcomes and allows for a refined, rejuvenated, lifted, rested appearance.

What activity do you do when the stress becomes too much these days?Cook. Ive been spending a lot of time with my cast-iron skillet. My cast-iron pizza is a favorite.

What have you been binge-watching? Ozark season three for suspense how good is Tom Pelphrey as Laura Linneys brother? And Cheers for laughs.

What has been an upside to this crazy time for you? My time with my wife and young sons, except during the screaming. And the homeschooling. And the cleaning.

Whats a good beauty treatment for someone whos stuck at home? Exfoliation. A downside of exfoliation is it can sometimes leave the skin dry and flaky, but if youre staying home, thats okay!

Conversely, what in your own grooming routine are you less on top of these days?Shaving, although my wife prefers a cleaner look, so early signs of a beard appear only now and then.

When this is all over, what are the first three to five things youll do or places youll go? The office will be my first stop! I miss my amazing patients! I expect Ill be there in overtime mode for a while getting everyone in. Id love a flat white at Laughing Man in Tribeca, maybe a burger at Odeon. Also we watched King Kong with the kids during quarantine, so my oldest wants me to take him to the top of the Empire State Building. He thinks King Kongs going to be there. I havent had the heart to set him straight.

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The Dermatologist Whos Obsessed With Sun Damage - The Cut

Normal human uterus is colonised by clones with cancer-driving mutations that arise early in life, study finds – Cambridge Network

The work, just published in Nature, provides insights into the earliest stages of uterine cancer development.

The endometrium is the inner part of the uterus, more commonly known as the womb lining. It is regulated by hormones such as oestrogen and progesterone and enters different states during childhood, reproductive years, pregnancy and after menopause.

Uterine cancer is the fourth most common cancer in women in the UK, accounting for five per cent of all new female cancer cases. Around 9,400 new cases are diagnosed every year, leading to the death of 2,300 women. Most cases occur in the seventh and eighth decades. Since the early 1990s, the incidence of uterine cancer has risen by 55 per cent in the UK*.

All cancers occur due to changes in DNA, known as somatic mutations, which continuously occur in all of our cells throughout life. A tiny fraction of these somatic mutations can contribute to a normal cell turning into a cancer cell and are known as driver mutations, which occur within a subset of cancer genes.

This study used whole-genome sequencing to better understand the genetic changes in healthy endometrial tissue. The team developed technology to sequence the genomes of small numbers of cells from individual glands in the endometrial epithelium, the tissue layer that sheds and regenerates during a womans menstrual cycle.

Laser-capture microscopy was used to isolate 292 endometrial glands from womb tissue samples donated by 28 women aged 19 to 81 years**, before DNA from each gland was whole-genome sequenced. The team then searched for somatic mutations in each gland by comparing them with whole genome sequences from other tissues from the same individuals.

The researchers found that a high proportion of cells carried driver mutations, even though they appeared completely normal under the microscope. Many of these driver mutations appear to have arisen early in life, in many cases during childhood.

Dr Luiza Moore, the lead researcher based at the Wellcome Sanger Institute, said: Human endometrium is a highly dynamic tissue that undergoes numerous cycles of remodelling during female reproductive years. We identified frequent cancer driver mutations in normal endometrium and showed that many such events had occurred early in life, in some cases even before adolescence. Over time, these mutant stem cells accumulate further driver mutations.

Despite the early occurrence of the first cancer-driver mutations, it takes several decades for a cell to accumulate the remaining drivers that will lead to invasive cancer. Typically, three to six driver mutations in the same cell are required for cancer to develop. As such, the vast majority of normal cells with driver mutations never convert into invasive cancers. When an invasive cancer develops, it may have been silently evolving within us for most of our lifetime.

Dr Kourosh Saeb-Parsy, University of Cambridge and Director of the Cambridge Biorepository for Translational Medicine (CBTM), said: Incidence of uterine cancers have been steadily rising in the UK for several decades, so knowing when and why genetic changes linked to cancer occur will be vital in helping to reverse this trend. This research is an important step and wouldnt have been possible without the individuals who gifted precious samples for this study, including transplant donors and their families.

Professor Sir Mike Stratton, Director of the Wellcome Sanger Institute, added: New technologies and approaches to investigating DNA mutations in normal tissues are providing profound insights into the procession of genetic changes that convert a normal cell into a cancer cell. The results indicate that, although most cancers occur at relatively advanced ages, the genetic changes that underlie them may have started early in life and we may have been incubating the developing cancer for most of our lifetime.

*Information and statistics about uterine cancers are available from the Cancer Research UK website: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/uterine-cancer

**The Cambridge Biorepository for Translational Medicine (CBTM) supports research requiring human tissue that aims to improve healthcare for patients. Tissue samples used in this study were from post-mortem or transplant donors, with samples also coming from biopsies for non-endometrial diseases. The authors would like to acknowledge all those who provided tissue used in this study, one third of whom were post-mortem or transplant donors. Their generous contribution is incredibly important for facilitating research that will help to improve the quality of healthcare for patients. https://www.cbtm.group.cam.ac.uk/aboutus

Luiza Moore, Daniel Leongamornlert and Tim H. H. Coorens et al. (2020). The mutational landscape of normal human endometrial epithelium. Nature. DOI: 10.1038/s41586-020-2214-z

Image: Endometrial_glands_Luiza Moore_ Wellcome Sanger Institute

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Normal human uterus is colonised by clones with cancer-driving mutations that arise early in life, study finds - Cambridge Network

Study provides new insight into the neural circuitry underlying irritability and anxiety in youths – PsyPost

New neuroimaging research published in JAMA Psychiatry helps to untangle the links between irritability, anxiety, and brain functioning in youths. The findings suggest that irritability and anxiety have interactive, rather than additive, effects when processing negative social information.

I am a practicing child and adolescent psychiatrist. Over the years, I have met with families struggling with all types of anxiety and irritability, explained study author Joel Stoddard of the University of Colorado and Childrens Hospital Colorado.

When I was early in my career, I began to appreciate that even though anxiety and irritability seem like straightforward symptoms, their presentation is often intermingled. We simply dont know why they co-occur or conversely why a child might have one symptom but not the other.

Moreover, there was very little work looking at both symptoms together, especially without a focus on traditional mental health diagnoses. At the time this study started, mental health research was moving away from traditional diagnoses because most arent well grounded in biology. Though the transition has been difficult, it also gave clinical scientists room to restart simply, said Stoddard, who also leads the Emotion and Development Lab.

In this study we examined symptoms in a group of children diagnosed with clinically significant affective issues. Are these symptoms related to how the basic emotion recognition circuitry responds to facial expressions?

The researchers used functional magnetic resonance imaging to examine the brain activity of 115 youths aged 8 to 17 years as they completed a face emotion processing task. About 90 of the participants had been diagnosed with anxiety, disruptive mood dysregulation, and/or attention-deficit/hyperactivity disorders. The youths and their parents also completed assessments of the participants irritability and anxiety.

Stoddard and his colleagues found that high levels of both anxiety and irritability were associated with decreased connectivity between the amygdala and medial prefrontal cortex when viewing angry facial expressions. High levels of anxiety but low levels of irritability, on the other hand, were associated with increased connectivity in this brain circuit. The amygdala is known to be important for responses to threatening situations, while the medial prefrontal cortex is associated with decision-making processes.

This is a demonstration that the response of amygdala-centered brain networks to emotional expressions differs by anxiety and irritability in children who we might very well see in the clinic, Stoddard told PsyPost.

Had we looked at either symptom alone, we might have missed how they respond differently. For example, we observed that changes in the prefrontal-amygdala network during viewing angry faces differ by an individuals degree of anxiety or irritability. These differences offer important clues about the neural function youth who may express anxiety, irritability, or both. But these are clues, I dont think much more should be taken from this study by itself.

Increased irritability by itself, meanwhile, was associated with increased activity in several brain regions in response to angry faces and happy faces compared to fearful faces.

But as with all research, the study includes some limitations.

This study used functional magnetic imaging in children with serious emotional issues, these facts are the source of strengths and weaknesses. Clearly major strengths are that we examined the clinical population directly and used a noninvasive, largely safe method of measuring localized brain activity. However, it is very difficult to get a good brain signal from youngsters because they move, causing a blurry image (especially for network imaging), or get tired of the task (so their brain responses may change), Stoddard explained.

Also, we could not ethically ask the participants to stop their medications or pause therapy risking harm. Also, if we did so, we might be studying the effects of discontinuation. On the other hand, if we only invited kids who didnt need treatment, we might not study a group of youth who represent the conditions we see in clinics. We also didnt focus on anxiety and irritability in some conditions like bipolar disorder or active posttraumatic stress or in different cultural contexts. Though there are caveats with each aspect of the study, it represents an interesting result and considerable effort by participants and experts.

This type of work is critical to build a strong foundation for understanding the brain mechanisms. It is part of a growing body of literature that is revealing how brain networks function differently by development, experience, or clinical symptoms. I personally find this emerging literature satisfying, because I see complicated clinical pictures. Some stories are simpler, such as dysfunction in a single gene or brain region. These occasionally explain a lot for rare conditions, but rarely much for common conditions, Stoddard added.

This work was a team effort. I contributed to it as part of my research training fellowship at the National Institutes of Mental Health and as an assistant professor at the University of Colorado, School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry. I continue to have that latter title and am an outpatient psychiatrist at the Childrens Hospital Colorado. Im supported by all those organizations to study pediatric anxiety and irritability. The content is solely my responsibility and does not necessarily represent the official views of the National Institutes of Health, the University of Colorado, or Childrens Hospital Colorado.

The study, Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology, was authored by Joel Stoddard, Wan-Ling Tseng, Pilyoung Kim, Gang Chen, Jennifer Yi, Laura Donahue, Melissa A. Brotman, Kenneth E. Towbin, Daniel S. Pine, and Ellen Leibenluft.

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Study provides new insight into the neural circuitry underlying irritability and anxiety in youths - PsyPost

VIDEO: Is It Allergies or COVID-19? – HealthDay Live – HealthDay Coronavirus Liveblog

Regular exercise can potentially prevent life-threatening cases of COVID-19, according to a review from Zhen Yan, a top exercise researcher at the University of Virginia School of Medicine.

Cardiovascular exercise increases the production of an antioxidant called extracellular superoxide dismutase (EcSOD). Yan compiled a comprehensive review of existing research to find that increased levels of this antioxidant protect the lungs from developing a severe complication associated with COVID-19, called acute respiratory distress syndrome (ARDS). Even a single session of exercise increases the production of this lung-protecting antioxidant.

Some cases of COVID-19 progress to the lungs and cause ARDS, a condition in which fluid collects in the lungs and deprives the body of oxygen. ARDS is a major cause of death in COVID-19 patients. Around 20% to 42% of patients hospitalized with the virus develop ARDS, and approximately 45% of those that develop severe cases of ARDS will die, according to the U.S. Center for Disease Control and Prevention and prior research.

Yan's review suggests that exercise can prevent or reduce the severity of ARDS, according to a press release about the project. "Regular exercise has far more health benefits than we know. The protection against this severe respiratory disease condition is just one of the many examples," said Yan. The findings were published in the journal Redox Biology.

Read the full press release.

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VIDEO: Is It Allergies or COVID-19? - HealthDay Live - HealthDay Coronavirus Liveblog

How effective is PLX cell therapy in treating coronavirus? Experts answer all queries and more – India TV News

Pluristem Therapeutics or PLX cell therapyuses placentas to grow smart cells, and programs them to secrete therapeutic proteins in the bodies of sick people. It has just treated its first American COVID-19 patient after treating seven Israelis. The patients were suffering from acute respiratory failure and inflammatory complications associated with Covid-19. Now, this theraphy is being touted as a possible 'cure'' for the deadly coronavirus with scientisst conducting varied researches on the same. In an exclusive interaction with India TV, doctors from India and abroadcame together for discussing about how effective can cell therapy be in treating coronavirus. Dr Solomon from Israel, Dr Anil Kaul from the US, DrSanjeev Chaubey from Shanghai and Dr Padma Srivastv and Dr Harsh Mahajan from India threw light upon the stem cell therapy and the possibility of incorporating the same in treating COVID-19 pateints.

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How effective is PLX cell therapy in treating coronavirus? Experts answer all queries and more - India TV News

‘I Will Not Kill Children to Live’ – Church Militant

TYLER, Texas (ChurchMilitant.com) - The bishop of Tyler, Texas has issued a pastoral letterrousing Catholics to understandthe mortal dangerof any coronavirusvaccine developed using stem cells from aborted babiesand is urgingthemto fight.

Announcing his April 23 letter, Bp. Joseph Strickland encouraged "all who believe in the Sanctity of Life in the womb" to reflect on his message, as "it is critical for the whole human family."

In the letter, Strickland explainedthat the pandemichas opened his eyes to the dangerousreality ofthe "use of in line stem cells from aborted babies in developing vaccines."

"I urge you to join me, NOW, in passionately but prayerfully speaking out against this practice," he urged.

"We must insist that legislators create legislation which establishes the illegal and immoral nature of any use of the remains of aborted babies for research," said Strickland. "Further, we must insist that pharmaceutical companies comply with such legislation." he said.

"I believe this can be a significant building block in a culture of life which eliminates the taint of economic gain that too easily infects the abortion industry," the bishop added.

Strickland stressed that there are ethical ways to develop vaccines. "Scientists I've spoken with assure me that there is no medical necessity for using aborted children in order to develop the much-needed vaccine to protect us from this particular strain of Coronavirus," he noted. "Thankfully, ethical means are available and can prove to be just as effective in developing vaccines; umbilical cells, placental cells, adult stem cells and other sources of cells, including even those of insects, provide completely viable paths to an effective vaccine.""We all know the sad saga of abortion in our nation and throughout the world which continues to grow more diabolical even as we energetically proclaim, with ever deeper clarity, the precious gift of every unborn child," he lamented.

Strickland declaredthatthis new threat a coronavirus vaccine fashioned from the cells of murdered childrenmust be countered.

"Just because the crime of abortion is considered legal in our nation does not mean it is morally permissible to use the dead bodies of these children to cure a global pandemic," he warned. "Emphatically, this practice is evil."

The bishop recalled how recent popes have raised their voices in defense of life from conception to natural death and to warn about the dangers of scientific research unchecked by moral truth.

Pope St. John Paul II's 1995 encyclical "The Gospel of Life" (Evangelium Vitae) warned of the growingclash between the "culture of death" and the "culture of life," reiterating,"The killing of innocent human creatures, even if carried out to help others, constitutes an absolutely unacceptable act."

Bishop Strickland also pointed to Pope Emeritus Benedict XVI's 1987 "Respect for Human Life" (Donum Vitae), whichgave clear warning that"what is technically possible is not for that very reason morally admissible."

He noted these historic pontificalpleas have gone largely unheeded.

Twice in theletterin both his opening and his conclusion Stricklandpromisedto help those who join their voices with his, vowing to helpthem"navigate the storm" of the current troubled times"as best he can."

The bishop also pledged that in the upcoming week he will provide a guide to assist the faithful "in speaking the truth to your elected officials, the pharmaceutical industry, and your local community."The guidewillbe posted on theSt. Philip Institute of Catechesis and Evangelizationwebsite,a resource center dedicated to teaching the Faith.

Speaking with Church Militant, Dr. Stacy Trasancos, Executive Director of the St. Philip Institute,summed up the significance of the bishop'shistoric call:

If we stand with Bp. Strickland and let it be known that we will refuse a vaccine made from the exploitation of aborted children, then we can influence the research, development, and market. I don't want to find myself a year from now being required to accept an immorally produced vaccine knowing that I did not speak up when I had the chance. I won't leave that legacy to my children and grandchildren.

Trasancos added, "Bishop Strickland is asking us all, the entire human race, to stand up with him and say, 'I will not kill children to live.'"

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'I Will Not Kill Children to Live' - Church Militant