FDA Approves Monjuvi(R) (tafasitamab-cxix) in Combination with Lenalidomide for the Treatment of Adu – PharmiWeb.com

DGAP-News: MorphoSys AG / Key word(s): Regulatory Approval 01.08.2020 / 01:43 The issuer is solely responsible for the content of this announcement.

FDA Approves Monjuvi(R) (tafasitamab-cxix) in Combination with Lenalidomide for the Treatment of Adult Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

- First FDA approval of a second-line treatment for adult patients with relapsed or refractory DLBCL, helping fill a high unmet medical need

- FDA granted Monjuvi Fast Track, Breakthrough Therapy and Priority Review designations

- MorphoSys and Incyte will co-commercialize Monjuvi in the United States

- Joint analyst and investor conference call and webcast scheduled for Monday, August 3, 2020 at 8:00 a.m. EDT / 2:00 p.m. CEST

PLANEGG/MUNICH, Germany - August 1, 2020 and WILMINGTON, Del. - July 31, 2020 MorphoSys AG (FSE: MOR; Prime Standard Segment; MDAX & TecDAX; NASDAQ:MOR) and Incyte (Nasdaq:INCY) today announced that the U.S. Food and Drug Administration (FDA) has approved Monjuvi(R) (tafasitamab-cxix) in combination with lenalidomide for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) not otherwise specified, including DLBCL arising from low grade lymphoma, and who are not eligible for autologous stem cell transplant (ASCT).1 Monjuvi, a humanized Fc-modified cytolytic CD19 targeting monoclonal antibody, has been approved under accelerated approval by the U.S. FDA based on overall response rate (ORR). Continued approval may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). The FDA decision represents the first approval of a second-line treatment for adult patients who progressed during or after first-line therapy.

DLBCL is the most common type of non-Hodgkin lymphoma in adults worldwide2, characterized by rapidly growing masses of malignant B-cells in the lymph nodes, spleen, liver, bone marrow or other organs. It is an aggressive disease with about one in three patients not responding to initial therapy or relapsing thereafter.3 In the United States each year approximately 10,000 patients are diagnosed with relapsed or refractory DLBCL who are not eligible for ASCT.4,5,6

"We are incredibly proud that the FDA has approved Monjuvi in combination with lenalidomide as the first treatment in second-line for patients with relapsed or refractory DLBCL, and we thank all the health care professionals, patients and families involved in our Monjuvi trials," said Jean-Paul Kress, M.D., Chief Executive Officer, MorphoSys. "This approval marks an important step in MorphoSys' transformation into a fully integrated biopharmaceutical company. We remain committed to developing innovative treatments to improve the lives of patients with serious diseases."

"The FDA approval of Monjuvi in combination with lenalidomide helps address an urgent unmet medical need for patients with relapsed or refractory DLBCL in the United States," said Herv Hoppenot, Chief Executive Officer, Incyte. "At Incyte we are committed to advancing patient care and are proud to bring this new and much-needed targeted therapeutic option to appropriate patients and the clinical community."

"The FDA approval of Monjuvi brings a new treatment option to patients in dire need across the United States," said Professor Gilles Salles, M.D., Chair of the Clinical Hematology Department at the University of Lyon, France, and lead investigator of the L-MIND study. "Today's FDA decision offers new hope for patients with this aggressive form of DLBCL who progressed during or after first-line therapy."

The FDA approval was based on data from the MorphoSys-sponsored Phase 2 L-MIND study, an open label, multicenter, single arm trial of Monjuvi in combination with lenalidomide as a treatment for adult patients with relapsed or refractory DLBCL. Results from the study showed an overall response rate (ORR) of 55% (primary endpoint), including a complete response (CR) rate of 37% and a partial response rate (PR) of 18%. The median duration of response (mDOR) was 21.7 months (key secondary endpoint).1 Warnings and Precautions for Monjuvi included infusion-related reactions (6%), serious or severe myelosuppression (including neutropenia (50%), thrombocytopenia (18%), and anemia (7%)), infections (73%) and embryo-fetal toxicity. Neutropenia led to treatment discontinuation in 3.7% of patients. The most common adverse reactions (>= 20%) were neutropenia, fatigue, anemia, diarrhea, thrombocytopenia, cough, pyrexia, peripheral edema, respiratory tract infection, and decreased appetite.

The FDA previously granted Fast Track and Breakthrough Therapy Designation for the combination of Monjuvi and lenalidomide in relapsed or refractory DLBCL. FDA Breakthrough Therapy designation is intended to expedite development and review of drug candidates. It is granted if preliminary clinical evidence indicates that the drug candidate may demonstrate substantial improvement over existing therapies in the treatment of a serious or life-threatening disease. The Biologics License Application (BLA) for Monjuvi was granted Priority Review and approved under the FDA's Accelerated Approval program.

Monjuvi is expected to be commercially available in the United States shortly. MorphoSys and Incyte will co-commercialize Monjuvi in the United States. Incyte has exclusive commercialization rights outside the United States.

MorphoSys and Incyte are committed to supporting patients throughout their treatment journeys and are working together to help lower patient access barriers. As part of this commitment, the Companies have launched My Mission Support, a robust patient support program offering financial assistance, ongoing education and other resources to eligible patients who are prescribed Monjuvi in the United States. Program information will be available online at http://www.MyMissionSupport.com.

Conference Call Information MorphoSys and Incyte will host an analyst and investor conference call and webcast on Monday, August 3, 2020 at 8:00 a.m. EDT / 2:00 p.m. CEST. The live webcast and replay will be available via http://www.morphosys.com and investor.incyte.com.

To access the conference call, please dial 877-407-3042 for callers in the United States or +1 201-389-0864 for callers outside the United States. When prompted, provide the conference identification number 13706810.

If you are unable to participate, a replay of the conference call will be available for 90 days. The replay dial-in number for the United States is 877-660-6853 and the dial-in number for international callers is +1 201-612-7415. To access the replay, you will need the conference identification number 13706810.

About L-MIND The L-MIND trial is a single arm, open-label Phase 2 study (NCT02399085) investigating the combination of tafasitamab and lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who have had at least one, but no more than three prior lines of therapy, including an anti-CD20 targeting therapy (e.g., rituximab), who are not eligible for high-dose chemotherapy or refuse subsequent autologous stem cell transplant The study's primary endpoint is overall response rate (ORR). Secondary outcome measures include duration of response (DoR), progression-free survival (PFS) and overall survival (OS). In May 2019, the study reached its primary completion.

For more information about L-MIND, visit https://clinicaltrials.gov/ct2/show/NCT02399085.

About Monjuvi(R) (tafasitamab-cxix) Monjuvi is a humanized Fc-modified cytolytic CD19 targeting monoclonal antibody. In 2010, MorphoSys licensed exclusive worldwide rights to develop and commercialize tafasitamab from Xencor, Inc. Tafasitamab incorporates an XmAb(R) engineered Fc domain, which mediates B-cell lysis through apoptosis and immune effector mechanism including antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP).

Monjuvi is approved by the U.S. Food and Drug Administration in combination with lenalidomide for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) not otherwise specified, including DLBCL arising from low grade lymphoma, and who are not eligible for autologous stem cell transplant (ASCT).

In January 2020, MorphoSys and Incyte entered into a collaboration and licensing agreement to further develop and commercialize Monjuvi globally. Monjuvi will be co-commercialized by Incyte and MorphoSys in the United States. Incyte has exclusive commercialization rights outside the United States.

A marketing authorization application (MAA) seeking the approval of tafasitamab in combination with lenalidomide in the EU has been validated by the European Medicines Agency (EMA) and is currently under review for the treatment of adult patients with relapsed or refractory DLBCL, including DLBCL arising from low grade lymphoma, who are not candidates for ASCT.

Tafasitamab is being clinically investigated as a therapeutic option in B-cell malignancies in a number of ongoing combination trials.

Monjuvi is a registered trademark of MorphoSys AG. XmAb(R) is a registered trademark of Xencor, Inc.

Important Safety Information What are the possible side effects of MONJUVI? MONJUVI may cause serious side effects, including:

- Infusion reactions. Your healthcare provider will monitor you for infusion reactions during your infusion of MONJUVI. Tell your healthcare provider right away if you get chills, flushing, headache, or shortness of breath during an infusion of MONJUVI.

- Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with MONJUVI, but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with MONJUVI. Tell your healthcare provider right away if you get a fever of 100.4 F (38 C) or above, or any bruising or bleeding.

- Infections. Serious infections, including infections that can cause death, have happened in people during treatments with MONJUVI and after the last dose. Tell your healthcare provider right away if you get a fever of 100.4 F (38 C) or above, or develop any signs and symptoms of an infection.

The most common side effects of MONJUVI include:

- Feeling tired or weak

- Diarrhea

- Cough

- Fever

- Swelling of lower legs or hands

- Respiratory tract infection

- Decreased appetite

These are not all the possible side effects of MONJUVI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before you receive MONJUVI, tell your healthcare provider about all your medical conditions, including if you:

- Have an active infection or have had one recently.

- Are pregnant or plan to become pregnant. MONJUVI may harm your unborn baby. You should not become pregnant during treatment with MONJUVI. Do not receive treatment with MONJUVI in combination with lenalidomide if you are pregnant because lenalidomide can cause birth defects and death of your unborn baby.

- You should use an effective method of birth control (contraception) during treatment and for at least 3 months after your final dose of MONJUVI.

- Tell your healthcare provider right away if you become pregnant or think that you may be pregnant during treatment with MONJUVI.

- Are breastfeeding or plan to breastfeed. It is not known if MONJUVI passes into your breastmilk. Do not breastfeed during treatment for at least 3 months after your last dose of MONJUVI.

You should also read the lenalidomide Medication Guide for important information about pregnancy, contraception, and blood and sperm donation.

Tell your healthcare provider about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Please see the full Prescribing Information for Monjuvi, including Patient Information, for additional Important Safety Information.

About MorphoSys MorphoSys is a commercial-stage biopharmaceutical company dedicated to the discovery, development and commercialization of exceptional, innovative therapies for patients suffering from serious diseases. The focus is on cancer. Based on its leading expertise in antibody, protein and peptide technologies, MorphoSys, together with its partners, has developed and contributed to the development of more than 100 product candidates, 27 of which are currently in clinical development. In 2017, Tremfya(R), marketed by Janssen for the treatment of plaque psoriasis, became the first drug based on MorphoSys' antibody technology to receive regulatory approval. Headquartered near Munich, Germany, the MorphoSys group, including the fully owned U.S. subsidiary MorphoSys US Inc., has ~500 employees. More information at http://www.morphosys.com.

Tremfya(R) is a registered trademark of Janssen Biotech.

About Incyte Incyte is a Wilmington, Delaware-based, global biopharmaceutical company focused on finding solutions for serious unmet medical needs through the discovery, development and commercialization of proprietary therapeutics. For additional information on Incyte, please visit Incyte.com and follow @Incyte.

MorphoSys Forward-Looking Statements This communication contains certain forward-looking statements concerning the MorphoSys group of companies, including the expectations regarding tafasitamab's ability to treat patients with relapsed or refractory diffuse large B-cell lymphoma, the further clinical development of tafasitamab, including ongoing confirmatory trials, additional interactions with regulatory authorities and expectations regarding future regulatory filings and possible additional approvals for tafasitamab as well as the commercial performance of tafasitamab. The words "anticipate," "believe," "estimate," "expect," "intend," "may," "plan," "predict," "project," "would," "could," "potential," "possible," "hope" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. The forward-looking statements contained herein represent the judgment of MorphoSys as of the date of this release and involve known and unknown risks and uncertainties, which might cause the actual results, financial condition and liquidity, performance or achievements of MorphoSys, or industry results, to be materially different from any historic or future results, financial conditions and liquidity, performance or achievements expressed or implied by such forward-looking statements. In addition, even if MorphoSys' results, performance, financial condition and liquidity, and the development of the industry in which it operates are consistent with such forward-looking statements, they may not be predictive of results or developments in future periods. Among the factors that may result in differences are MorphoSys' expectations regarding risks and uncertainties related to the impact of the COVID-19 pandemic to MorphoSys' business, operations, strategy, goals and anticipated milestones, including its ongoing and planned research activities, ability to conduct ongoing and planned clinical trials, clinical supply of current or future drug candidates, commercial supply of current or future approved products, and launching, marketing and selling current or future approved products, the global collaboration and license agreement for tafasitamab, the further clinical development of tafasitamab, including ongoing confirmatory trials, and MorphoSys' ability to obtain and maintain requisite regulatory approvals and to enroll patients in its planned clinical trials, additional interactions with regulatory authorities and expectations regarding future regulatory filings and possible additional approvals for tafasitamab as well as the commercial performance of tafasitamab, MorphoSys' reliance on collaborations with third parties, estimating the commercial potential of its development programs and other risks indicated in the risk factors included in MorphoSys' Annual Report on Form 20-F and other filings with the U.S. Securities and Exchange Commission. Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements. These forward-looking statements speak only as of the date of publication of this document. MorphoSys expressly disclaims any obligation to update any such forward-looking statements in this document to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements, unless specifically required by law or regulation.

Incyte Forward-Looking Statements Except for the historical information set forth herein, the matters set forth in this press release contain predictions, estimates and other forward-looking statements, including without limitation statements regarding: tafasitamab's ability to treat patients with relapsed or refractory diffuse large B-cell lymphoma, the further clinical development of tafasitamab, including ongoing confirmatory trials , additional interactions with regulatory authorities and expectations regarding future regulatory filings and possible additional approvals for tafasitamab as well as the commercial performance of tafasitamab. These forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially, including unanticipated developments in and risks related to: obtaining regulatory approval for this planned collaboration; research and development efforts related to the collaboration programs; the possibility that results of clinical trials may be unsuccessful or insufficient to meet applicable regulatory standards or warrant continued development; other market or economic factors, including other scientific developments; unanticipated delays; the effects of market competition; risks associated with relationships between collaboration partners; the impact of governmental actions regarding pricing, importation and reimbursement for pharmaceuticals; and such other risks detailed from time to time in each company's reports filed with the U.S. Securities and Exchange Commission, including Incyte's annual report on Form 10-Q for the quarter ending March 31, 2020 and MorphoSys' Annual Report on Form 20-F for the fiscal year ended December 31, 2019. Each party disclaims any intent or obligation to update these forward-looking statements.

References

1. Monjuvi(R) (tafasitamab-cxix) Prescribing Information. Boston, MA, MorphoSys.

2. Sarkozy C, et al. Management of relapsed/refractory DLBCL. Best Practice Research & Clinical Haematology. 2018 31:209-16. doi.org/10.1016/j.beha.2018.07.014.

3. Skrabek P, et al. Emerging therapies for the treatment of relapsed or refractory diffuse large B cell lymphoma. Current Oncology. 2019 26(4): 253-265. doi.org/10.3747/co.26.5421.

4. DRG Epidemiology data.

5. Kantar Market Research (TPP testing 2018).

6. Friedberg, Jonathan W. Relapsed/Refractory Diffuse Large B-Cell Lymphoma. Hematology Am Soc Hematol Educ Program 2011; 2011:498-505. doi: 10.1182/asheducation-2011.1.498.

For more information, please contact:

01.08.2020 Dissemination of a Corporate News, transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement.

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FDA Approves Monjuvi(R) (tafasitamab-cxix) in Combination with Lenalidomide for the Treatment of Adu - PharmiWeb.com

Animal Stem Cell Therapy Market Growth, Trends and Value Chain 2019-2025 – Owned

Animal Stem Cell Therapy Market 2018: Global Industry Insights by Global Players, Regional Segmentation, Growth, Applications, Major Drivers, Value and Foreseen till 2024

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Global Stem Cell Assay Market 2020 Trends Analysis and Coronavirus (COVID-19) Effect Analysis | Key Players Market With COVID-19 Impact Analysis, In…

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Cell Therapy Manufacturing Market is estimated to reach close to USD 11 Billion by 2030, predicts Roots Analysis – Market Research Posts

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Cell Therapy Manufacturing Market is estimated to reach close to USD 11 Billion by 2030, predicts Roots Analysis - Market Research Posts

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The Global Cytokine market swot is provided for the international markets including progress trends, competitive landscape breakdown, and key in regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed.

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The Cytokine Market is expected to witness a CAGR of 7.9% during the forecast period. North America dominate the global market due to the increasing prevalence of cancer in that region.

Increased Acceptance in Cancer Therapy

Cytokines are critical for tumor immune surveillance, and have demonstrated therapeutic anti-tumor activity in murine models and in the clinical treatment of several human cancers. To date, two cytokines have FDA approval as single agents for cancer treatment: high-dose, bolus IL-2 for metastatic melanoma and renal cell carcinoma and IFN- for the adjuvant therapy of Stage III melanoma. So, increased acceptance in cancer therapy is driving market of Global Cytokine Market. Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. Mesenchymal stem cells (MSCs) have emerged as major new cell technology, with a diverse spectrum of potential clinical applications. So, its potential contribution in stem cell therapy is also driving the Global Cytokine Market. Additionally, potential biomarker for neonatal sepsis is also contributing towards the growth of Global cytokine market.

Short Half-Lives of Drug

Cytokines have inherently short half-life, which necessitates prolonged administration of cytokine therapies. This is a major problem in maintaining an effective dose over a long period. This becomes an even greater issue when cytokine is administered systematically. The short half-life of cytokines, the production of cytokines by cells in peripheral blood preparations, and the potential degradation make the stability, treatment, and storage of biological samples important factors in circulating cytokine measurement, analysis, and interpretation. Additionally, lacks of specificity in cytokines is also restraining the growth of Global Cytokine Market.

North America is dominating the market

North America is dominating the cytokine market due to the rising prevalence of cancer in that region. Numerous animal tumor model studies have demonstrated that cytokines have broad anti-tumor activity and this has been translated into a number of cytokine-based approaches for cancer therapy. As per the Cancer Statistics in 2016, an estimated 1.6 million new cases of cancer were diagnosed in the United States, with prevalence expected to rise to almost 19 million by 2024. Augmenting growth in the R&D of cancer therapy, along with lesser side effects (as compared to chemotherapy) have predisposed cytokine therapy, which is a non-specific immunotherapy. This factor has increased the market share of cytokines, among cancer therapies in the United States.

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The global Cytokine market covers the vision of participant analysis by product types, market share, applications, sales, and revenue.

Highlighted points of Cytokine Market Size:

Key Developments in the Cytokine Market:

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Functional Coil Coatings Market 2020 Industry Insights by Share, Emerging Trends, Regional Analysis, Segments, Prime Players, Drivers, Growth Factor and Foreseen till 2026

Functional Coil Coatings Market 2020 Industry Insights by Share, Emerging Trends, Regional Analysis, Segments, Prime Players, Drivers, Growth Factor and Foreseen till 2026

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Global Cytokine Market 2020 Top Countries Data Industry Size, Share, Business Growth, Revenue, Trends, Market Demand Penetration and Forecast to By...

What’s On The Ballot? A Summary Of The 12 State Propositions For November 2020 Election – KHTS Radio

When Santa Clarita residents cast their ballots in November during the 2020 election, they will have the opportunity to vote on a dozen state propositions ranging from cash bail to affirmative action.

At the beginning of July, the Office of the California Secretary of State posted the 12 statewide ballot measures that had qualified for the 2020 election on Nov. 3.

Out of the dozen state propositions set to be voted on in November, eight were placed on the ballot by citizens and special interests, while four were put on by state legislators.

With issues ranging from lifting the decades-old ban on affirmative action to the fate of the cash bail system in California, here are the 12 state propositions Santa Clarita residents are set to vote on in November.

Bonds

Only one state bond measure made it onto the ballot this year, with this one going towards the funding of stem cell research.

Prop 14: Authorize Bonds to Continue Funding Stem Cell and Other Medical Research

This proposition would authorize $5.5 billion in state general obligation bonds to fund grants from the California Institute of Regenerative Medicine to educational, non-profit, and private entities for three things:

As part of this, $1.5 billion would also go towards funding research and therapy for Alzheimers, Parkinsons, stroke, epilepsy and other brain and central nervous system diseases and conditions, according to the propositions text.

See Related: COC Measure E Committee, COC Foundation Fined $14,500 For Campaign Violations

The California Institute for Regenerative Medicine was initially created after California voters passed Proposition 71 in 2004, which allowed the state to borrow roughly $3 billion to create the institute.

While payments on the bond would be postponed for an initial five years, money from the states General Fund would be used to pay back the estimated $7.8 billion cost of the bond (principal of $5.5 billion, interest of $2.3 billion).

Housing/Real Estate

There are three measures on the 2020 ballot that pertain to housing and real estate, including the controversial issues of rent control and the split roll tax.

Prop 15: Increases Funding for Public Schools, Community Colleges, and Local Government Services by Changing Tax Assessment of Commercial and Industrial Property

More commonly known as the split roll tax, this proposition would require certain commercial and industrial properties to be taxed based on their current market value, as opposed to the market value when the property was originally purchased.

Proposition 15 would overturn a portion of Proposition 13, a measure passed by California voters in 1978 that capped property taxes from increasing as the market value of a piece of property increased.

Residential and agricultural properties would be exempt from the measure, as well as commercial and industrial properties with a combined value of $3 million or less.

State officials say that an estimated $7.5 billion to $12 billion would be generated each year, the majority of which would go towards public schools and local governments.

Prop 19: ACA 11: The Home Protection for Seniors, Severely Disabled, Families, and Victims of Wildfire or Natural Disasters Act

This measure would allow eligible homeowners to transfer their tax assessments anywhere within the state and allow tax assessments to be transferred to a more expensive home with an upward adjustment

Additionally, it would increase the number of times that a person over the age of 55 or an individual with severe disabilities can transfer their tax assessments from one to three.

The measure also requires that any homes that a person inherits and does not use as a principal residence to be reassessed using the market value at the time of the transfer.

The majority of funds raised by this measure would go towards combating wildfires, as well as local counties.

Prop 21: Expands Local Governments Authority to Enact Rent Control on Residential Property

This proposition would amend state law to allow local governments to establish rent control on residential properties over 15 years old.

State legislators had previously passed a law in 2019 that set a seven percent ceiling on how much landlords can raise their rents each year.

The measure exempts single-family homes owned by landlords with no more than two properties.

If the measure is passed, state officials estimated a potential reduction in state and local revenues of tens of millions of dollars per year in the long term, depending on the actions that local communities take.

Civil Rights

The largest section of the 2020 ballot is dedicated to various civil rights issues ranging from affirmative action to lifting some voting restrictions.

Prop 16: ACA 5: Government Preferences

Proposition 16 would repeal an amendment to the state constitution that bans the practice of affirmative action within state institutions.

Passed in 1996, Proposition 209 amended the California Constitution to prohibit any public agency from discriminating against, or granting preferential treatment to, any individual or group on the basis of race, sex, color, ethnicity or national origin.

See Related: Senator Scott Wilk Votes To Put Repeal Of State Affirmative Action Ban On November Ballot

Republican State Senator Scott Willk, who represents Santa Clarita Valley as part of the 21st Senate District, crossed the aisle and voted to put this measure on the ballot, stating at the time that with the conversations many citizens have been having around their dinner tables the past few weeks, it is reasonable to let voters revisit this issue.

The measure was introduced by Democratic Assemblywoman Shirley Weber of San Diego.

Prop 17: ACA 6: Elections: Disqualification of Electors

If passed, Proposition 17 would allow individuals who were out of prison on parole for a felony conviction to vote.

Under the California Constitution, felons are disqualified from voting until both their imprisonment and parole are completed.

Proposition 17 would amend the state constitution to allow felons out on parole to vote, restoring the right to vote to an estimated 40,000 Californians.

The measure was introduced by Democratic Assemblyman Kevin McCarty of Sacramento.

Prop 18: ACA 4: Elections: Voting Age

This measure would allow 17-year-olds to vote in primary and special elections, provided that they will be 18 at the time of the subsequent general election.

This is the first time that such a measure has made it onto the ballot, despite lawmakers pushing similar efforts several times in the past.Similar measures have already been approved in at least 18 other states, as well as Washington D.C.

The proposition was introduced by Democratic Assemblyman Kevin Mullin of San Mateo

Prop 24: Amends Consumer Privacy Laws

Proposition 24 would expand consumer data privacy laws in the state of California, which are already considered the strongest in the nation.

Under this measure, consumers would be allowed to:

In addition to prohibiting businesses from retaining personal information for longer than reasonably necessary, the measure also triples maximum penalties for certain violations concerning consumers under the age of 16.

The proposition would also establish the California Privacy Protection Agency in order to enforce and implement consumer privacy laws, and impose administrative fines.

Criminal Justice

Two measures pertaining to criminal justice are on the ballot this year, with one addressing the future of the cash bail system within the state of California.

Prop 20: Restricts Parole for Non-Violent Offenders. Authorizes Felony Sentences For Certain Offenses Currently Treated Only as Misdemeanors

If passed, Proposition 20 would add crimes to the list of violent felonies for which early parole is restricted, allow prosecutors to charge certain misdemeanor crimes with felony charges, and require people convicted of specified misdemeanors to submit to collection of DNA samples for a state database.

Under the measure, those who are convicted of domestic violence, as well as other crimes that are currently categorized as nonviolent, would no longer be considered for early parole.

See Related: Dozens Of Residents Protest Against Human Trafficking In Valencia

Additionally, the passage of the proposition would make specific types of theft and fraud crimes such as firearm theft, vehicle theft, and unlawful use of a credit card chargeable as misdemeanors or felonies, rather than just misdemeanors.

The ballot initiative also establishes two new types of crimes in state code (serial crime and organized retail crime), which could be charged as either a misdemeanor or a felony.

Prop 25: Referendum to Overturn a 2018 Law That Replaced Money Bail System with a System Based on Public Safety Risk

This measure looks to uphold contested legislation that replaces Californias cash bail system with risk assessments for detained suspects awaiting trials.

In 2018, state legislators passed Senate Bill 10, which eliminated the cash bail system, and instead gave judges the role in determining whether or not an arrested individual should be held in jail or not leading up to their trial based on the risk that they pose to others or themself.

The law also restricts pretrial detentions for many misdemeanor charges.

Voting yes on Proposition 25 would uphold the 2018 law, while voting no would overturn it and bring back cash bail to California.

Labor

The final two ballot initiatives on this years ballot involve labor regulations, including a vote on whether or not to reclassify ride-share drivers as independent contractors.

Prop 22: Changes Employment Classification Rules for App-Based Transportation and Delivery Drivers

Proposition 22 would reclassify drivers for ride-share apps or food delivery services as independent contractors, essentially overturning a significant portion of Assembly Bill 5 (AB 5), which was passed in September of 2019.

This would exempt companies such as Uber and Lyft from standard wage and hour restrictions.

In exchange, companies with independent-contractor drivers would be required to provide specified alternative benefits, such as minimum compensation and healthcare subsidies, vehicle insurance, and sexual harassment policies.

The ballot initiative was largely funded by Uber, DoorDash and Lyft.

Prop 23: Authorizes State Regulation of Kidney Dialysis Clinics. Establishes Minimum Staffing and Other Requirements

This ballot initiative would require at least one licensed physician on site during treatment at outpatient kidney dialysis clinics.

Clinics would also be required to report data on dialysis-related infections to the state health department, as well as obtain consent from the same department before closing.

Additionally, Proposition 23 would prohibit clinics from discriminating against patients based on the source of payment for care.

State officials estimate that the measure would likely increase dialysis costs, resulting in increased state and local health care costs by tens of millions of dollars each year.

Ed. Note: The full text for all of the ballot measures can be read here.

KHTS FM 98.1 and AM 1220 is Santa Claritas only local radio station. KHTS mixes in a combination of news, traffic, sports, and features along with your favorite adult contemporary hits. Santa Clarita news and features are delivered throughout the day over our airwaves, on our website and through a variety of social media platforms. Our KHTS national award-winning daily news briefs are now read daily by 34,000+ residents. A vibrant member of the Santa Clarita community, the KHTS broadcast signal reaches all of the Santa Clarita Valley and parts of the high desert communities located in the Antelope Valley. The station streams its talk shows over the web, reaching a potentially worldwide audience. Follow @KHTSRadio on Facebook, Twitter, and Instagram.

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What's On The Ballot? A Summary Of The 12 State Propositions For November 2020 Election - KHTS Radio

Covid-19 Impact on Global Adipose Derived Stem Cell Therapy Market Strategies, Comparison, Shares, Demand, Supply, Challenges and Forecast to 2026 -…

The report on Adipose Derived Stem Cell Therapy, gives an in-depth analysis of Global Adipose Derived Stem Cell Therapy Market based on aspects that are very important for the market study. Factors like production, market share, revenue rate, regions and key players define a market study start to end. This report gives an overview of market valued in the year 2019 and its growth in the coming years till 2026. The report is based on the in-depth view of Adipose Derived Stem Cell Therapy industry on the basis of market growth, market size, development plans and opportunities offered by the global Adipose Derived Stem Cell Therapy market. The energetic aspects studied in this report include SWOT analysis, feasibility and forecast information.

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Major companies of this report:

AlloCure Mesoblast Cellleris Antria Intrexon Celgene Corporation Tissue Genesis Cytori Therapeutics Corestem Pluristem Therapeutics Cyagen BioRestorative Therapies Lonza Pluristem Therapeutics Celltex Therapeutics Corporation iXCells Biotechnologies

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Moreover, the report provides historical information with future forecast over the forecast period. Some of the important aspects analyzed in the report includes market share, production, key regions, revenue rate as well as key players. This Adipose Derived Stem Cell Therapy report also provides the readers with detailed figures at which the Adipose Derived Stem Cell Therapy market was valued in the historical year and its expected growth in upcoming years. Besides, analysis also forecasts the CAGR at which the Adipose Derived Stem Cell Therapy is expected to mount and major factors driving markets growth. The study on global Adipose Derived Stem Cell Therapy market, offers deep insights about the Adipose Derived Stem Cell Therapy market covering all the crucial aspects of the market.

Adipose Derived Stem Cell Therapy Market Segmentation by Type:

Autologous Stem Cells Allogeneic Stem Cells

Adipose Derived Stem Cell Therapy Market Segmentation by Application:

Therapeutic Application Research Application

In addition, the report include deep dive analysis of the market, which is one of the most important features of the market. Furthermore, the need for making an impact is likely to boost the demand for the experts which are working in the market. Moreover, an in depth analysis of the competitors is also done to have an estimate for the market. The Adipose Derived Stem Cell Therapy market has its impact all over the globe. On global level Adipose Derived Stem Cell Therapy industry is segmented on the basis of product type, applications, and regions. It also focusses on market dynamics, Adipose Derived Stem Cell Therapy growth drivers, developing market segments and the market growth curve is offered based on past, present and future market data. The industry plans, news, and policies are presented at a global and regional level.

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At Orbispharma we curate the most relevant news stories, features, analysis and research reports on the important challenges undertaken by the pharmaceutical and related sectors. Our editorial philosophy is to bring you sharp, focused and informed perspective of industries, the end users and application of all upcoming trends into the pharma sector. Orbispharma believes in conversations that can bring a change in one of the most crucial economic sectors in the world. With these conversations we wish our customers to make sound business decisions with right business intelligence.

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Covid-19 Impact on Global Adipose Derived Stem Cell Therapy Market Strategies, Comparison, Shares, Demand, Supply, Challenges and Forecast to 2026 -...

Personalized Cell Therapies Market Trends, Outlook, and Opportunity Analysis up to 2021 focuses on major key players PCT Cell Therapy Services, LLC…

The latest fundamental insights on Personalized Cell Therapies Market with COVID-19 Industry Impact, Forecast Development Scope, and Growth Prospects 2021-2026 is released by PBI. Every market driver, Personalized Cell Therapies marketing channel, growth-driving segments, risk analysis & mitigation is given in this report. The dynamic effects on worldwide Personalized Cell Therapies economies and crucial primary & secondary data sources offered in this study. The Personalized Cell Therapies Industry competitive landscape, regional analysis, future patterns, Top companies, current development rate, & gross margin status is provided.

The Personalized Cell Therapies Industry landscape view, demand, revenue, market share & pricing structure analysis is offered. The changing Industry dynamics, plans, CAGR, COVID-19 impact on consumer demand, availability of raw materials is analyzed completely. The market development rate during 2020-2025 with past & present industry performance is assessed in this report.

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The top companies & competitive landscape study is as follows:

PCT Cell Therapy Services, LLC (U.S),S. Stem Cell, Inc. (U.S),Bellicum Pharmaceuticals, Inc. (U.S),Saneron CCEL Therapeutics, Inc. (U.S),StemGenex (U.S),Vericel Corporation.(U.S)

By Cell Type

Market Analysis By Regions

Asia-Pacific (China, Japan, Korea, India and Southeast Asia)

North America (United States, Canada and Mexico)

Europe (Germany, France, UK, Russia and Italy)

South America (Brazil, Argentina, Columbia)

Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

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Below is the TOC of the report:

Executive Summary

Assumptions and Acronyms Used

Research Methodology

Personalized Cell Therapies Market Overview

Personalized Cell Therapies Supply Chain Analysis

Personalized Cell Therapies Pricing Analysis

Global Personalized Cell Therapies Market Analysis and Forecast by Type

Global Personalized Cell Therapies Market Analysis and Forecast by Application

Global Personalized Cell Therapies Market Analysis and Forecast by Sales Channel

Global Personalized Cell Therapies Market Analysis and Forecast by Region

North America Personalized Cell Therapies Market Analysis and Forecast

Latin America Personalized Cell Therapies Market Analysis and Forecast

Europe Personalized Cell Therapies Market Analysis and Forecast

Asia Pacific Personalized Cell Therapies Market Analysis and Forecast

Middle East & Africa Personalized Cell Therapies Market Analysis and Forecast

Competition Landscape

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Personalized Cell Therapies Market Trends, Outlook, and Opportunity Analysis up to 2021 focuses on major key players PCT Cell Therapy Services, LLC...

Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies Market Size, Share, Types, Products, Trends, Growth, Applications and Forecast 2020 to 2027…

New Jersey, United States,- The research report on Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies market comprises of insights in terms of pivotal parameters such as production as well as the consumption patterns alongside revenue estimations for the projected timeframe. Speaking of production aspects, the study offers an in-depth analysis regarding the manufacturing processes along with the gross revenue amassed by the leading producers operating in this business arena. The unit cost deployed by these producers in various regions during the estimated timeframe is also mentioned in the report.

Significant information pertaining to the product volume and consumption value is enlisted in the document. Additionally, the report contains details regarding the consumption graphs, Individual sale prices, and import & export activities. Additional information concerning the production and consumption patterns are presented in the report.

In market segmentation by manufacturers, the report covers the following companies-

Exploring the growth rate over a period

Business owners looking to scale up their business can refer this report that contains data regarding the rise in sales within a given consumer base for the forecast period, 2020 to 2027. Product owners can use this information along with the driving factors such as demographics and revenue generated from other products discussed in the report to get a better analysis of their products and services. Besides, the research analysts have compared the market growth rate with product sales to enable business owners to determine the success or failure of a specific product or service.

By Type

By Application

Regions Covered in the Global Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies Market:

The Middle East and Africa (GCC Countries and Egypt)

North America (the United States, Mexico, and Canada)

South America (Brazil etc.)

Europe (Turkey, Germany, Russia UK, Italy, France, etc.)

Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Highlights of the Report:

Accurate market size and CAGR forecasts for the period 2020-2026

Identification and in-depth assessment of growth opportunities in key segments and regions

Detailed company profiling of top players of the global Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies market

Exhaustive research on innovation and other trends of the global Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies market

Reliable industry value chain and supply chain analysis

Comprehensive analysis of important growth drivers, restraints, challenges, and growth prospects

The scope of the Report:

The report offers a complete company profiling of leading players competing in the global Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies marketwith a high focus on the share, gross margin, net profit, sales, product portfolio, new applications, recent developments, and several other factors. It also throws light on the vendor landscape to help players become aware of future competitive changes in the global Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies market.

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Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage, and more. These reports deliver an in-depth study of the market with industry analysis, the market value for regions and countries, and trends that are pertinent to the industry.

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Stem Cell And Platelet Rich Plasma Prp Alopecia Therapies Market Size, Share, Types, Products, Trends, Growth, Applications and Forecast 2020 to 2027...