Global Stem Cell Media Market Competitive Dynamics and Industry Outlook 2025 – 3rd Watch News

Report Summary:,The global Stem Cell Media market report is a comprehensive study that encompasses top manufacturers, prospective market share, revenue, purchaser volume with respect to dealing volume and global segmentation for the Stem Cell Media industry. The report further includes market classification and definitions, product and industry overview, manufacturing specifications and cost structure, included raw materials and so on.

In addition to the vast definitive data, the report also sheds light on the past behavior of the market and an upcoming growth graph that is expected to venture in an upwards trajectory despite market fluctuations and trends.

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Market Segmentation:,The Stem Cell Media report follows an accumulated research methodology that is based on years of experience combined with structured data points acquired from proprietary sources. These methods function with thorough research and analysis split between primary and secondary research combined with an in-house data wrangling process. In general, the data points are gathered from a variety of sources such as vendor projections, product list, research papers and a detailed list of manufacturers. The analysis is than derived into quantitative market values such as qualitative and quantitative qualities, market forecast models, market segmentations and business models that revolve around the Stem Cell Media industry.

Moreover, the Stem Cell Media market report clarifies the market segmentation based on various parameters and attributes that can be classified on geographical region, product types and market applications.

The report provides a comprehensive analysis of the Stem Cell Media industry market by types, applications, players and regions. This report also displays the production, Consumption, revenue, Gross margin, Cost, Gross, market share, CAGR, and Market influencing factors of the Stem Cell Media industry in USA, EU, China,India, Japan and other regions, and forecast to 2025, from 2019.

Market Analysis by Players,Thermo Fisher,STEMCELL Technologies,Merck Millipore,Lonza,GE Healthcare,Miltenyi Biotec,Corning,CellGenix,Takara,PromoCell

Market Analysis by Regions:,USA,Europe,Japan,China,India,Southeast Asia,South America,South Africa,Others

Market Analysis by Types:,Pluripotent Stem Cell Culture,Hematopoietic Stem Cell Culture,Mesenchymal Stem Cell Culture,Others

Market Analysis by Applications:,Scientific Research,Industrial Production

The report also focuses on developing market trends, preferred market channels and market drivers & restraints to name a few.

Major Point of TOC:

Chapter One: Stem Cell Media Market Overview

Chapter Two: Global Stem Cell Media Competitions by Players

Chapter Three: Global Stem Cell Media Competitions by Types

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Chapter Four: Global Stem Cell Media Competitions by Application

Chapter Five: Global Stem Cell Media Production Market Analysis by Region

Chapter Six: Global Stem Cell Media Sales Market Analysis by Region

Chapter Seven: Imports and Exports Market Analysis

Chapter Eight: Global Stem Cell Media Players Profiles and Sales Data

Chapter Nine: Stem Cell Media Upstream and Downstream Analysis

Chapter Ten: Global Stem Cell Media Market Forecast (2017-2022)

Chapter Eleven: Research Findings and Conclusion, Continue

About HongChun Research:HongChun Research main aim is to assist our clients in order to give a detailed perspective on the current market trends and build long-lasting connections with our clientele. Our studies are designed to provide solid quantitative facts combined with strategic industrial insights that are acquired from proprietary sources and an in-house model.

Contact Details:Jennifer GrayManager Global Sales+ 852 8170 0792[emailprotected]

NOTE: Our report does take into account the impact of coronavirus pandemic and dedicates qualitative as well as quantitative sections of information within the report that emphasizes the impact of COVID-19.

As this pandemic is ongoing and leading to dynamic shifts in stocks and businesses worldwide, we take into account the current condition and forecast the market data taking into consideration the micro and macroeconomic factors that will be affected by the pandemic.

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Global Stem Cell Media Market Competitive Dynamics and Industry Outlook 2025 - 3rd Watch News

Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Development, Trends, Key Driven Factors, Segmentation And Forecast to 2020-2026 – Cole of…

Other

The report is a compilation of different studies, including regional analysis where leading regional Platelet Rich Plasma and Stem Cell Alopecia Treatment markets are comprehensive studied by market experts. Both developed and developing regions and countries are covered in the report for a 360-degree geographic analysis of the Platelet Rich Plasma and Stem Cell Alopecia Treatment market. The regional analysis section helps readers to become familiar with the growth patterns of important regional Platelet Rich Plasma and Stem Cell Alopecia Treatment markets. It also provides information on lucrative opportunities available in key regional Platelet Rich Plasma and Stem Cell Alopecia Treatment markets.

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Table of Content

1 Introduction of Platelet Rich Plasma and Stem Cell Alopecia Treatment Market

1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology

3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Outlook

4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market, By Deployment Model

5.1 Overview

6 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market, By Solution

6.1 Overview

7 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market, By Vertical

7.1 Overview

8 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market, By Geography

8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Competitive Landscape

9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix

11.1 Related Research

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Tags: Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Size, Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Trends, Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Growth, Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Forecast, Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Analysis Sarkari result, Government Jobs, Sarkari naukri, NMK, Majhi Naukri,

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Platelet Rich Plasma and Stem Cell Alopecia Treatment Market Development, Trends, Key Driven Factors, Segmentation And Forecast to 2020-2026 - Cole of...

The Impact of the Coronavirus on the Nerve Repair and Regeneration Market Growth, Trends and Competitive Landscape | P&S Intelligence – Cole of Duty

The prevalence of neurological disorders and chronic pain is increasing rapidly at the present time across the globe. Depression, fecal incontinence, epilepsy, Parkinsons, and Alzheimers are the different kinds of neurological disorders. As per the Alzheimers Association, about 5.35 million people aged 65 years and above were suffering from Alzheimers diseases in the U.S. in 2015. Apart from this, as per the Parkinsons Diseases Foundation, nearly 60,000 new cases of Parkinsons disease are reported each year in the U.S. Attributed to these reasons, the demand for efficient medical technologies, such as neuromodulation and neurostimulation devices, is increasing rapidly.

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The different applications of the nerve repair and regeneration devices are stem cell therapy, neurostimulation and neuromodulation surgeries, nerve grafting, and direct nerve repair/neurorrhaphy. Out of these, the largest demand for different nerve repair and regeneration devices was created for neurostimulation and neuromodulation surgeries in the past. Ambulatory surgery centers and hospitals & clinics are the major end users of the nerve repair and regeneration devices. Between these two, the hospitals & clinics category is predicted to witness the fastest growth in the coming years because of the surging patient pool, increasing geriatric population, and improving healthcare infrastructure.

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The potential of stem cell therapy in the field is predicted to create wide opportunities for players operating in the nerve repair and regeneration market. Stem cell therapy is an emerging branch of medicine which has the potential of restoring tissue and /or organ function in patients suffering from critical injuries or chronic diseases. According to clinical research findings, stem cell therapy provides better quality as compared to nerve graft surgeries. Moreover, research is going on in the field of stem cell therapy for its application in the treatment of Alzheimers disease and Parkinsons disease. This is further expected to drive the market in the near future.

About P&S Intelligence

P&S Intelligence is a provider of market research and consulting services catering to the market information needs of burgeoning industries across the world. Providing the plinth of market intelligence, P&S as an enterprising research and consulting company, believes in providing thorough landscape analyses on the ever-changing market scenario, to empower companies to make informed decisions and base their business strategies with astuteness.

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The impact of the coronavirus on the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Size, Analysis, and Forecast Report 2019-2023 Cole…

Companies in the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market are vying suggestive steps to tackle the challenges resulting from the COVID-19 (Coronavirus) pandemic. Exhaustive research about COVID-19 is providing present-day techniques and alternative methods to mitigate the impact on Coronavirus on the revenue of the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market.

The report on the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market provides a birds eye view of the current proceedings and advancements within the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies landscape. Further, the report ponders over the various factors that are likely to impact the overall dynamics of the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market over the forecast period (20XX-20XX) including the current trends, business expansion opportunities and restraining factors amongst others.

As per the market report suggested by ResearchMoz.us, the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market is expected to register a CAGR growth of ~XX% during the forecast period and attain a value of ~US$XX by the end of 20XX. Further, the report suggests that the growth of the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market is largely influenced by a range of factors including, emphasis on R&D innovations by market players, surging investments to increase product portfolio, and favorable regulatory policies among others.

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Questions Related to the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Explained:

Competitive Landscape

The report provides critical insights related to the leading players operating in the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market. The revenue generated, market presence, product range, and financials of each company are enclosed in the report.

The key players covered in this studyOrange County Hair Restoration CenterHair Sciences Center of ColoradoAnderson Center for HairEvolution Hair Loss InstituteSavola Aesthetic Dermatology CenterVirginia Surgical CenterHair Transplant Institute of MiamiColorado Surgical Center & Hair Institute

Market segment by Type, the product can be split intoPlatelet Rich Plasma InjectionsStem Cell TherapyMarket segment by Application, split intoDermatology ClinicsHospitals

Market segment by Regions/Countries, this report coversNorth AmericaEuropeChinaJapanSoutheast AsiaIndiaCentral & South America

The study objectives of this report are:To analyze global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies status, future forecast, growth opportunity, key market and key players.To present the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies development in North America, Europe, China, Japan, Southeast Asia, India and Central & South America.To strategically profile the key players and comprehensively analyze their development plan and strategies.To define, describe and forecast the market by type, market and key regions.

In this study, the years considered to estimate the market size of Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies are as follows:History Year: 2015-2019Base Year: 2019Estimated Year: 2020Forecast Year 2020 to 2026For the data information by region, company, type and application, 2019 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

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Regional Landscape

The regional landscape of the report provides resourceful insights related to the revenue share analysis of the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market in different regions. Further, the market attractiveness of each region provides players a clear understanding of the overall growth potential in each regional market.

End-User Analysis

The report provides an in-depth understanding of the various end-users of the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies along with the market share, size, and revenue generated by each end-user.

Important Information that can be extracted from the Report:

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The impact of the coronavirus on the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Size, Analysis, and Forecast Report 2019-2023 Cole...

Warning about stem cell treatments and COVID-19 – 10News

SAN DIEGO (KGTV) With the search for a coronavirus cure, researchers say unproven stem cell products are being pushed as treatment for COVID-19.

"I think these businesses kind of tap into very vulnerable populations. People who are looking for help, maybe theyre hopeful, maybe theyre desperate," said Leigh Turner, a bioethicist at the University of Minnesota.

Turner has been studying the direct-to-consumer marketing of stem cell therapies and related products for nearly a decade.

His recent paper about "Preying on Public Fears and Anxieties in a Pandemic" recently appeared in the journal Cell Stem Cell. He focused on businesses that were making marketing representations that were not compliant with federal law.

"Theyre not accurate. Theyre not evidence-based," Turner said.

His research said that businesses make vague claims on their websites about stem cell treatments for COVID-19. He mentioned one Southern California anti-aging clinic that used YouTube videos to promote "stem cell exosome" products that were shipped to clients homes.

Turner also wrote about an Arizona regenerative medicine that advertised stem cell therapy as a "precautionary measure" for preventing COVID-19.

"I think its both illegal and unethical," Turner said.

The FDA has sent letters to businesses in several states warning them about their unsubstantiated claims of coronavirus prevention and treatment.

"Do everything you can to avoid being scammed because this is a moment where there are a lot of people out there trying to do helpful things in all kinds of ways, but there are other individuals who see this as an opportunity to make money," Turner said.

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Warning about stem cell treatments and COVID-19 - 10News

Research frozen by COVID-19 begins to thaw – The Age

Last week, she was given the all-clear to start re-entering the lab after it closed in March due to COVID-19 restrictions.

"We fired up the lab and turned everything back on. It felt fantastic to be back working towards research goals," she said.

Professor Sharon Ricardo's lab was closed under COVID-19 restrictions.Credit:Jason South

Over the last few months, she has been churning through grant writing and zoom meetings.

She said her days spent video-conferencing and doing administrative work were "tiring but productive".

Professor Ricardo said a healthy balance between laboratory work and paperwork was important to her and her team as they "became researchers because we get excited about what we do".

They produce three-dimensional miniature kidneys from skin cells useful for disease modelling, called organoids.

The organoids are made by collecting patients' skin cells, developing them into stem cells, and "adding factors to the cell cultures to form mini kidneys," she said.

According to Professor Ricardo, the closure of the laboratories has seriously impeded some of her student's research.

One of her PhD students had one organoid experiment left to go when the restrictions came in to play and labs were closed.

"We had to freeze the lines and turn off all the incubators," she said.

The Universitys labs are reopening gradually. Hygiene and social distancing measures were being taken to ensure the safety of staff and students, she said.

"You go to the lab, perform what you need to do, and go home," said Professor Ricardo. Shes received strict instructions not to hang around the office.

Even with the new social distancing measures, she is very excited to be back with her colleagues.

"Every time I see somebody at work, I feel like I am seeing my best friend," she said.

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Universities Australia Chief Executive Catriona Jackson said COVID-19 has "upended almost every area of endeavour" across the university research sector.

"Australias researchers have pivoted their work to join the community in fighting the virus, from world-leading vaccine and treatment research to work on all aspects of the deep social and economic impact of the crisis," she said.

The pandemic has been devastating for the university research community. "The loss to university R&D [research and development] is estimated at $2.5 billion in 2020, placing at risk at least 38 per cent of research salaries," said Ms Jackson.

While specific regulations around reopening physical research facilities differ for each state and university, Ms Jackson said they are closely following guidance from medical authorities and government.

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Research frozen by COVID-19 begins to thaw - The Age

Animal Stem Cell Therapy Market Development, Trends, Key Driven Factors, Segmentation And Forecast to 2020-2026 – Cole of Duty

Research Organizations

The report is a compilation of different studies, including regional analysis where leading regional Animal Stem Cell Therapy markets are comprehensive studied by market experts. Both developed and developing regions and countries are covered in the report for a 360-degree geographic analysis of the Animal Stem Cell Therapy market. The regional analysis section helps readers to become familiar with the growth patterns of important regional Animal Stem Cell Therapy markets. It also provides information on lucrative opportunities available in key regional Animal Stem Cell Therapy markets.

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Table of Content

1 Introduction of Animal Stem Cell Therapy Market

1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology

3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Animal Stem Cell Therapy Market Outlook

4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Animal Stem Cell Therapy Market, By Deployment Model

5.1 Overview

6 Animal Stem Cell Therapy Market, By Solution

6.1 Overview

7 Animal Stem Cell Therapy Market, By Vertical

7.1 Overview

8 Animal Stem Cell Therapy Market, By Geography

8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Animal Stem Cell Therapy Market Competitive Landscape

9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix

11.1 Related Research

Get Complete Report

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Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage and more. These reports deliver an in-depth study of the market with industry analysis, market value for regions and countries and trends that are pertinent to the industry.

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Tags: Animal Stem Cell Therapy Market Size, Animal Stem Cell Therapy Market Trends, Animal Stem Cell Therapy Market Growth, Animal Stem Cell Therapy Market Forecast, Animal Stem Cell Therapy Market Analysis Sarkari result, Government Jobs, Sarkari naukri, NMK, Majhi Naukri,

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Animal Stem Cell Therapy Market Development, Trends, Key Driven Factors, Segmentation And Forecast to 2020-2026 - Cole of Duty

Stem Cell Alopecia Treatment Market 2020 Global Overview, Growth, Size, Opportunities, Trends, Leading Company Analysis and Forecast to 2026 – Cole of…

Sanford Burnham Prebys Medical Discovery Institute

All of the product type and application segments of the Stem Cell Alopecia Treatment market included in the report are deeply analyzed based on CAGR, market size, and other crucial factors. The segmentation study provided by the report authors could help players and investors to make the right decisions when looking to invest in certain market segments.

The Essential Content Covered in the Stem Cell Alopecia Treatment Market Report :

* Top Key Company Profiles.* Main Business and Rival Information* SWOT Analysis and PESTEL Analysis* Production, Sales, Revenue, Price and Gross Margin* Market Share and Size

The report is a compilation of different studies, including regional analysis where leading regional Stem Cell Alopecia Treatment markets are comprehensive studied by market experts. Both developed and developing regions and countries are covered in the report for a 360-degree geographic analysis of the Stem Cell Alopecia Treatment market. The regional analysis section helps readers to become familiar with the growth patterns of important regional Stem Cell Alopecia Treatment markets. It also provides information on lucrative opportunities available in key regional Stem Cell Alopecia Treatment markets.

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Table of Content

1 Introduction of Stem Cell Alopecia Treatment Market

1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology

3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Stem Cell Alopecia Treatment Market Outlook

4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Stem Cell Alopecia Treatment Market, By Deployment Model

5.1 Overview

6 Stem Cell Alopecia Treatment Market, By Solution

6.1 Overview

7 Stem Cell Alopecia Treatment Market, By Vertical

7.1 Overview

8 Stem Cell Alopecia Treatment Market, By Geography

8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Stem Cell Alopecia Treatment Market Competitive Landscape

9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix

11.1 Related Research

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New Stem Cell-Based Topical Solution Helps Bald People Regrow Hair – SciTechDaily

A clinical trial showed the ability of a stem cell-based topical solution to regrow hair in people with male/female pattern baldness.

The results of a clinical trial released today (May 18, 2020) in STEM CELLS Translational Medicinedemonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness.

Androgenetic alopecia (AGA) commonly known as male-pattern baldness (female-pattern baldness in women) is a condition caused by genetic, hormonal and environmental factors. It affects an estimated 50 percent of all men and almost as many women older than 50. While it is not a life-threatening condition, AGA can lower a persons self-esteem and psychological well-being. There are a few FDA-approved medications to treat hair loss, but the most effective can have side effects such as loss of libido and erectile dysfunction. Therefore, the search continues for a safer, effective treatment.

Adipose tissue-derived stem cells (ADSCs) secrete several growth hormones that help cells develop and proliferate. According to laboratory and experimental studies, growth factors such as hepatocyte growth factor (HGF), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF) and platelet-derived growth factor (PDGF) increase the size of the hair follicle during hair development.

A more enriched adipose-derived stem cells-constituent extract (ADSC-CE) with stem cell proteins is obtained by disruption of the ADSC membrane using a low frequency of ultrasound wave. Credit: AlphaMed Press

Recent studies have shown that ADSCs promote hair growth in both men and women with alopecia. However, no randomized, placebo-controlled trial in humans has explored the effects and safety of adipose-derived stem cell constituent extract (ADSC-CE) in AGA. We aimed to assess the efficacy and tolerability of ADSC-CE in middle-aged patients with AGA in our study, hypothesizing that it is an effective and safe treatment agent, said Sang Yeoup Lee, M.D., Ph.D., of the Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital in South Korea. He led the group of researchers, which also included colleagues from Pusan National University School of Medicine, Pusan National University Yangsan Hospital and T-Stem Co., Ltd.

The team recruited 38 patients (29 men and nine women) with AGA and assigned half to an intervention group that received the ADSC-CE topical solution and half as a control group that received a placebo. Twice daily, each patient applied the ADSC-CE topical solution or placebo to their scalp using their fingers.

At the end of 16 weeks, the group that received the ADSC-CEs had a significant increase in both hair count and follicle diameter, reported the studys senior author, Young Jin Tak, M.D., Ph.D.

Dr. Lee added, Our findings suggest that the application of the ADSC-CE topical solution has enormous potential as an alternative therapeutic strategy for hair regrowth in patients with AGA, by increasing both hair density and thickness while maintaining adequate treatment safety. The next step should be to conduct similar studies with large and diverse populations in order to confirm the beneficial effects of ADSC-CE on hair growth and elucidate the mechanisms responsible for the action of ADSC-CE in humans.

For the millions of people who suffer from male-pattern baldness, this small clinical trial offers hope of a future treatment for hair regrowth, said Anthony Atala, M.D., Editor-in-Chief ofSTEM CELLS Translational Medicineand director of the Wake Forest Institute for Regenerative Medicine. The topical solution created from proteins secreted by stem cells found in fat tissue proves to be both safe and effective. We look forward to further findings that support this work.

###

Reference: A Randomized, Double-blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia by Young Jin Tak, Sang Yeoup Lee, A Ra Cho and Young Sil Kim, 18 May 2020, STEM CELLS Translational Medicine.DOI: 10.1002/sctm.19-0410

AboutSTEM CELLS Translational Medicine:STEM CELLS Translational Medicine(SCTM), co-published by AlphaMed Press and Wiley, is a monthly peer-reviewed publication dedicated to significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices. SCTM is the official journal partner of Regenerative Medicine Foundation.

About AlphaMed Press: Established in 1983, AlphaMed Press with offices in Durham, NC, San Francisco, CA, and Belfast, Northern Ireland, publishes two other internationally renowned peer-reviewed journals:STEM CELLS, celebrating its 38th year, is the worlds first journal devoted to this fast paced field of research.The Oncologist, also a monthly peer-reviewed publication, entering its 25th year, is devoted to community and hospital-based oncologists and physicians entrusted with cancer patient care. All three journals are premier periodicals with globally recognized editorial boards dedicated to advancing knowledge and education in their focused disciplines.

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New Stem Cell-Based Topical Solution Helps Bald People Regrow Hair - SciTechDaily

Clinical Trial Shows Topical Stem Cell Treatment Leads to Hair Regrowth in Common Type of Baldness – Technology Networks

The results of a new clinical trial published in the journal STEM CELLS Translational Medicine demonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness.1

Unfortunately, there are only a few FDA-approved medications to treat hair loss, and these carry a myriad of associated side effects including a negative impact on sexual functioning. There is therefore a pertinent need to develop anti-hair loss treatments that lack such side effects.

Emerging research has demonstrated the potential application of stem cells, particularly adipose tissue-derived stem cells (ADSCs), in this space. ADSCs are a type of mesenchymal stem cell that secrete several growth hormones that facilitate cell development and proliferation.

As previous research has demonstrated that growth factors such as hepatocyte growth factor, vascular endothelial growth factor, insulin-like growth factor and platelet-derived growth factor increase the size of hair follicles during hair development, scientists have explored whether ADSCs can promote hair growth in men and women with alopecia.2,3 The results of such research have been positive, however, a randomized, placebo-controlled trial of such a therapeutic approach in AGA did not exist until now.

"Recent studies have shown that ADSCs promote hair growth in both men and women with alopecia. However, no randomized, placebo-controlled trial in humans has explored the effects and safety of adipose-derived stem cell constituent extract (ADSC-CE) in AGA," says Sang Yeoup Lee, M.D., Ph.D., of the Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital. "We aimed to assess the efficacy and tolerability of ADSC-CE in middle-aged patients with AGA in our study, hypothesizing that it is an effective and safe treatment agent."

Participants were instructed to apply 2mL of solution to the area in which they experienced hair loss, twice every day for a total of 16 weeks, massaging the solution into their scalp using their fingers. Each subjected visited the research center four times in total throughout the study, and were requested to keep a diary to record when they were using the solution.

To measure whether the solution was significantly impacting hair growth, the scientists measured changes in total hair number and hair thickness as confirmed by close contract photographs using a standardized technique. This was the primary efficacy variable. Photographs were taken at baseline, eight weeks and 16 weeks after using the product. At baseline, participants received a dot tattoo over their scalp to ensure that the photographs were taken at the same spot at each follow up. The secondary efficacy variables of the study included analysis of global photographs of the participants' scalps by an investigator, and self-evaluation of hair growth by the participants.

Whilst these results are promising, the authors note several limitations to the study. When assessing the secondary efficacy outcomes, the researchers found that the improvement score provided by the investigator was higher in the intervention group than the control, but this was not a significant increase. Additionally, the evaluation provided by the subject was lower in the intervention group. The scientists suggest that a contributing factor here could be the study duration, positing the idea that the length of time in which the participants were involved in the trial may not have been sufficient for them to notice a visual improvement. Furthermore, the self-report assessment could have been limited in validity as subjects may have been impacted by their own expectations towards the intervention. A solution to consider going forward could be to ask participants about their expectations regarding the magnitude of improvement at baseline.

Lee adds, "Our findings suggest that the application of the ADSC-CE topical solution has enormous potential as an alternative therapeutic strategy for hair regrowth in patients with AGA, by increasing both hair density and thickness while maintaining adequate treatment safety. The next step should be to conduct similar studies with large and diverse populations in order to confirm the beneficial effects of ADSC-CE on hair growth and elucidate the mechanisms responsible for the action of ADSC-CE in humans."

"For the millions of people who suffer from male-pattern baldness, this small clinical trial offers hope of a future treatment for hair regrowth," says Anthony Atala, M.D., Editor-in-Chief ofSTEM CELLS Translational Medicineand director of the Wake Forest Institute for Regenerative Medicine. "The topical solution created from proteins secreted by stem cells found in fat tissue proves to be both safe and effective. We look forward to further findings that support this work."

References:

1. Tak, Lee, Cho and Kim. (2020). A randomized, doubleblind, vehiclecontrolled clinical study of hair regeneration using adiposederived stem cell constituent extract in androgenetic alopecia. Stem Cells Translational Medicine. DOI: https://doi.org/10.1002/sctm.19-0410.

2. Ramdasi S, Tiwari SK. (2016). Growth factors and cytokines secreted in conditioned media by mesenchymal stem cells-promising possible therapeutic approach for hair regeneration. J Stem Cells. https://www.ncbi.nlm.nih.gov/pubmed/28296872.

3. Lee et al. (2001). Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation. J Dermatol Sci. 25:156-163.

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Clinical Trial Shows Topical Stem Cell Treatment Leads to Hair Regrowth in Common Type of Baldness - Technology Networks