Category Archives: Stell Cell Research


Late-Term Abortion and an Election in Virginia – Newsmax

Is there a point too far for even pro-choice Americans to accept when it comes to abortion?

Nick Bell is betting there is, and that point is after birth!

Bell, a Republican, is running for the legislature in the heavily Democratic 39th district in Virginia. Why? Because, he says, a friend sent him a video of Virginia Democrat Kathy Tran talking about the bill she was proposing (in January, tabled for now) to repeal restrictions on late-term abortions.

Asked how late in the third trimester could a physician perform an abortion because of the mothers mental health, Tran answered: I mean, through the third trimester. The third trimester goes all the way to 40 weeks.

When Governor Ralph Northam of Virginia doubled down in explaining the bill and supported infanticide in the now infamous interview on WTOP radio, saying that if a woman went into labor while an abortion was being performed, the infant would be delivered, the infant would be kept comfortable and the infant would be resuscitated if thats what the mother and the family desired, Bell realized someone needs to step up. This is about a fully-formed person literally on a table, crying; this has nothing to do with politics everyone can agree that that life must be protected. (You can see clips from the Tran and Northam videos in Bells campaign ad, here.)

Bell is correct that the majority of Americans understand this, are against late-term abortion, and aghast at infanticide. However, many are swayed by the relentless propaganda of the media in collusion with the abortion industry, who tell them they are misunderstanding the reach of such legislation.

Defenders of Tran and Northam repeat things like, this would only be for severely disabled fetuses, meaning that 1) it is ok to kill persons who are disabled; and 2) skirting the fact that the mother sometimes with the father gets to decide what is severe, which might mean inconvenient.

Proponents also say things like: Trust women! No women would choose a late-term abortion for anything but a heart wrenching, tragic situation.

Really? Why? Because all women are good? Because no women are coerced?

I wrote here about Melissa Ohden, whose mother was coerced into an attempted abortion, and whose grandmother, a nurse, instructed the doctor to let born-alive Melissa die on the table. But a nurse could not stand seeing the baby struggling to breathe and rushed her to the NICU, saving her life.

Another common rationale: Come on, these late-term or born-alive situations represent a tiny number of the overall abortion rate. So? If something is wrong, say, homicide, all kinds of it are wrong, even if some of the more gruesome methods let say, beheading account for a tiny number of the overall body count.

This is the kind of dangerous anti-logic spouted by Bells opponent, Vivian Watts, who, is so extreme, Bell says, she makes Tran look like an angel.

From her website:

When Life Begins: I believe the very complex decision of when life begins is deeply personal, moral decision.

Huh? I know that, even though it is quite obvious scientifically that a new life begins at conception, some like to argue that life doesnt begin until fertilization, or when a heartbeat is detected. But what Watts is saying is, its really up to us to decide, as long as we claim complexity. According to this reasoning, if a woman decides in a complex and personal manner that her daughters life doesnt begin until her fourth birthday, she should have the "right" to kill her three-year-old.

Watts goes on: "I will continue to defend that position in all of the challenging and complex ways that it comes before the Virginia General Assembly, including birth control; in vitro fertilization; a women's right to an abortion under Roe v. Wade; a persons right to have an advanced medical directive carried out; and stem cell research in the treatment of disease and disabilities."

To be clear: what she supports is Tran's bill, which goes far beyond Roe; she supports the killing of human embryos in stem cell research to aid treatment for people with diseases or disabilities, but only if those persons are not already killed just before or after birth because they have a disease or disability. And to top it off, she supports parents deciding on their own when life begins.

The bottom line is this: In a moral society, law is supposed to protect life.

Cant everyone can agree that life must be protected?

Lets hope Nick Bell's truth-telling rings loud and clear in Virginia.

Maria McFadden Maffucci is the editor of the Human Life Review, http://www.humanlifereview.com, a quarterly journal devoted to the defense of human life, founded in 1974 by her father, James P. McFadden, Associate Publisher of National Review. She is President of the Human Life Foundation, based in midtown Manhattan, which publishes the Review and supports pregnancy resource centers. Mrs. Maffuccis articles and editorials have appeared in the Human Life Review, First Things, National Review Online, National Review, Verily, and Crux. A Holy Cross graduate with a BA in Philosophy, she is married to Robert E. Maffucci, and the mother of three children. Her interests include exploring opportunities for individuals with special needs. To read more of her reports Click Here Now.

2019 Newsmax. All rights reserved.

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Late-Term Abortion and an Election in Virginia - Newsmax

AIVITA Biomedical Announces Publication Detailing Immune Mechanisms Leading to Complete Remission of Measurable Metastatic Melanoma in Patient Treated…

IRVINE, Calif., Oct. 30, 2019 /PRNewswire/ --AIVITA BiomedicalInc., a biotechnology company specializing in innovative stem cell applications, announced the publication of an article titled "Genomic, Proteomic, and Immunologic Associations with a Durable Complete Remission of Measurable Metastatic Melanoma Induced by a Patient-Specific Dendritic Cell Vaccine" in the journal Human Vaccines and Immunotherapeutics. Robert O. Dillman, M.D., Chief Medical Officer at AIVITA, Gabriel Nistor, M.D., Chief Science Officer, and Aleksandra J. Poole, Ph.D., Vice President, Research & Development, authored the article.

The article focuses on a melanoma patient treated in a prior Phase 2 study with AIVITA's immunotherapy, autologous dendritic cells loaded with autologous tumor antigens derived from tumor-initiating cells. The analyses concern the immune mechanism of action that led to a complete response in the patient with progressive, refractory, metastatic melanoma. The analyses included elucidation of the genes in the patient's tumor cells and normal cells, more than 100 blood markers before and after vaccination, and the patient's immune cells.

The article is available at Taylor & Francis Online here: https://doi.org/10.1080/21645515.2019.1680239

CLINICAL TRIAL DETAIL

OVARIAN CANCER

AIVITA's ovarian Phase 2 double-blind study is active and enrolling approximately 99 patients who are being randomized in a 2:1 ratio to receive either the autologous cancer stem cell-targeting immunotherapy or autologous monocytes as a comparator.

Patients eligible for randomization and treatment will be those (1) who have undergone debulking surgery, (2) for whom a cell line has been established, (3) who have undergone leukapheresis from which sufficient monocytes were obtained, (4) have an ECOG performance grade of 0 or 1 (Karnofsky score of 70-100%), and (5) who have completed primary therapy. The trial is not open to patients with recurrent ovarian cancer.

For additional information about AIVITA's AVOVA-1 trial patients can visit: http://www.clinicaltrials.gov/ct2/show/NCT02033616

GLIOBLASTOMA

AIVITA's glioblastoma Phase 2 single-arm study is active and is enrolling approximately 55 patients to receive the cancer stem cell-targeting immunotherapy.

Patients eligible for treatment will be those (1) who have recovered from surgery such that they are about to begin concurrent chemotherapy and radiation therapy (CT/RT), (2) for whom an autologous tumor cell line has been established, (3) have a Karnofsky Performance Status of > 70 and (4) have undergone successful leukapheresis from which peripheral blood mononuclear cells (PBMC) were obtained that can be used to generate dendritic cells (DC). The trial is not open to patients with recurrent glioblastoma.

For additional information about AIVITA's AV-GBM-1 trial please visit: http://www.clinicaltrials.gov/ct2/show/NCT03400917

MELANOMA

AIVITA's melanoma Phase 1B open-label, single-arm study will establish the safety of administering anti-PD1 monoclonal antibodies in combination with AIVITA's cancer stem cell-targeting immunotherapy in patients with measurable metastatic melanoma. The study will also track efficacy of the treatment for the estimated 14 to 20 patients. This trial is not yet open for enrollment.

Patients eligible for treatment will be those (1) for whom a cell line has been established, (2) who have undergone leukapheresis from which sufficient monocytes were obtained, (3) have an ECOG performance grade of 0 or 1 (Karnofsky score of 70-100%), (4) who have either never received treatment for metastatic melanoma or were previously treated with enzymatic inhibitors of the BRAF/MEK pathway because of BRAF600E/K mutations and (5) are about to initiate anti-PD1 monotherapy.

For additional information about AIVITA's AV-MEL-1 trial please visit: http://www.clinicaltrials.gov/ct2/show/NCT0374329

About AIVITA Biomedical

AIVITA Biomedical is a privately held company engaged in the advancement of commercial and clinical-stage programs utilizing curative and regenerative medicines. Founded in 2016 by pioneers in the stem cell industry, AIVITA Biomedical utilizes its expertise in stem cell growth and directed, high-purity differentiation to enable safe, efficient and economical manufacturing systems which support its therapeutic pipeline and commercial line of skin care products.

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SOURCE AIVITA Biomedical, Inc.

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AIVITA Biomedical Announces Publication Detailing Immune Mechanisms Leading to Complete Remission of Measurable Metastatic Melanoma in Patient Treated...

CHS teacher enjoys prepping students for life out on their own – Albuquerque Journal

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Angelica Williams poses in front of the periodic chart in her Cleveland High classroom. The daughter of educators, her father, Rudy Aragon, was once an assistant principal at Rio Rancho High School; before that Aragon was the varsity boys basketball coach at Los Lunas High School Current Observer sports editor Gary Herron covered his team for the Valencia County News-Bulletin.(Gary Herron/ Rio Rancho Observer)

Hows this response after telling your mother youve decided on a career?

When I told my mom I was gonna be a teacher, she cried, recalled Angelica Olivas, arguably one of the most-popular teachers at Cleveland High School.

It wasnt unanimous, but to anyone seated in the schools gymnasium a few weeks ago when the 2019 Stormcoming court was introduced, a majority of the court members touted Olivas as most-inspirational.

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Heres a sample of what members of the court said about her: She made one student believe in herself; she made another student smile on days she didnt want to; and she had taught a male student hard work, to stay focused and that mitochondria is the powerhouse of the cell.

In education, we dont feel appreciated all the time, Olivas said. For me, my appreciation comes when I get those accolades from students, preparing them for life.

My goal is to make a difference, she added. I build a really healthy rapport with my students; respect is a two-way street.

Olivass popularity didnt come as a surprise to CHS Principal Scott Affentranger.

Kids love her because she creates great relationships with them, he said. She cares and they see that she cares; she teaches and they see that she teaches. She is visible with kids after hours and at school events, and kids get to see that she loves teaching, loves to see them after hours in activities and athletics, and she is dedicated to the Storm and she wears that dedication on her sleeve.

She is a respected and valued CHS staff member and Im proud to be her colleague, Affentranger continued. Also, she teaches AP Biology, which is a tough course to teach, and as a student, take and do well in.

Affentranger said Olivas has taught at CHS since it opened in 2009, and is a good cheer coach.

Olivas who was a cheerleader, cross country runner and soccer and basketball player at Peasco High School is an assistant for the Storms new head cheerleading coach, Kyla (Ortega) LiRosi, a Storm alum. When the head coach abruptly resigned in the middle of last school year, LiRosi and Olivas shared head-coaching duties.

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This teaching career resulted when Olivas realized that following the long path to being in the medical profession would be tough for her as a young, single mother.

Growing up in northern New Mexico, she was the Class of 1998 valedictorian at Peasco High, where her father was the principal. She then headed to Colorado Springs, where she attended Colorado College.

I was gonna be a doctor. I had a daughter at an early age 19 and decided (as a college senior) to be a teacher, she said.

Thats about the time her mother, Tina Aragon, a former teacher, cried at hearing the news.

Olivas graduated on time, figuring she might be able to do lab work or research as a career.

Her first classroom job was in the eighth-grade wing at Rio Rancho Mid-High, team-teaching with the late Lori Sturgess.

My first year was chaotic, she recalled. I was 22 and teaching; I worked on alternative licensure because I was only qualified for biology.

A teacher in high school turned me on to biology, she recalled.

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Now, though, shes highly qualified in all the sciences and teaches a college-level class.

She also sponsors the Dream Makers Club at CHS, for students interested in the medical profession anything medical related, Olivas said.

She has about 40 students in that club, which she founded about six years ago.

Needless to say, the teaching profession has changed since Olivas was at PHS, namely because of social media.

We had pagers, she said, laughing at the memory. I think social media can be a positive thing. We have Chromebooks (but) we used cellphones in the past for research.

Ive seen a shift in students and their parents, she added. Most of the parents are pretty supportive.

Her favorite subject has changed, too.

We now have a better understanding of whats going on at the cellular level, she said. The human genome program has been huge; with stem-cell research, were still behind (other countries) because of regulations. Religious beliefs have held it back.

Many residents were happy to read that the states teachers received a 6-percent increase in their salaries this year.

Im making less money now than I was last year, Olivas admitted, after a 5-percent increase in their insurance premiums. Thats a little frustrating, but if we were doing it for the money, nobody would be doing it.

In this profession, every day is a different adventure, she said. Making a difference in one kids life is life-changing.

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CHS teacher enjoys prepping students for life out on their own - Albuquerque Journal

bluebird bio Reports Third Quarter 2019 Financial Results and Highlights Operational Progress – Business Wire

CAMBRIDGE, Mass.--(BUSINESS WIRE)--bluebird bio, Inc. (NASDAQ: BLUE) today reported financial results and business highlights for the third quarter ended September 30, 2019.

During the third quarter we advanced our country-by-country launch plans in Europe and, with the recent approval of the commercial drug product manufacturing specifications for ZYNTEGLO, we moved one step closer to our goal of treating patients suffering from TDT in early 2020, said Nick Leschly, chief bluebird. Also this quarter, we presented updated data from the Phase 2/3 Starbeam study in patients with CALD. To report that patients continued to be free of MFDs at up to five years of follow-up is something were tremendously proud to do for these families, and we look forward to advancing that program in the regulatory process next year. Looking ahead, we plan to provide clinical updates for ZYNTEGLO and across the rest of our portfolio, including LentiGlobin in sickle cell disease, bb21217 in multiple myeloma, and from our registration-enabling KarMMa study of ide-cel in patients with multiple myeloma by the end of this year. Id like to thank all the bluebirds around the globe for their tireless focus on doing the right thing for our patients weve seen amazing progress thus far in 2019 and I look forward to ending the year on a strong note.

Recent Highlights:

TDT

CALD

COMPANY

Upcoming Anticipated Milestones:

Third Quarter 2019 Financial Results

About bluebird bio, Inc.bluebird bio is pioneering gene therapy with purpose. From our Cambridge, Mass., headquarters, were developing gene therapies for severe genetic diseases and cancer, with the goal that people facing potentially fatal conditions with limited treatment options can live their lives fully. Beyond our labs, were working to positively disrupt the healthcare system to create access, transparency and education so that gene therapy can become available to all those who can benefit.

bluebird bio is a human company powered by human stories. Were putting our care and expertise to work across a spectrum of disorders by researching cerebral adrenoleukodystrophy, sickle cell disease, transfusion-dependent -thalassemia and multiple myeloma using three gene therapy technologies: gene addition, cell therapy and (megaTAL-enabled) gene editing.

bluebird bio has additional nests in Seattle, Wash.; Durham, N.C.; and Zug, Switzerland. For more information, visit bluebirdbio.com.

Follow bluebird bio on social media: @bluebirdbio, LinkedIn, Instagram and YouTube.

ZYNTEGLO, LentiGlobin and Lenti-D are trademarks of bluebird bio, Inc.

The full common name for ZYNTEGLO: A genetically modified autologous CD34+ cell enriched population that contains hematopoietic stem cells transduced with lentiviral vector encoding the A-T87Q-globin gene.

Forward-Looking StatementsThis release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding the companys financial condition, results of operations, as well as statements regarding the plans for regulatory submissions and commercialization for ZYNTEGLO and the companys product candidates, including anticipated regulatory milestones, planned commercial launches, planned clinical studies, as well as the companys intentions regarding the timing for providing further updates on the development and commercialization of ZYNTEGLO and the companys product candidates. Any forward-looking statements are based on managements current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, the risks that the preliminary positive efficacy and safety results from our prior and ongoing clinical trials will not continue or be repeated in our ongoing or future clinical trials, the risk of cessation or delay of any of the ongoing or planned clinical studies and/or our development of our product candidates, risks that the current or planned clinical trials of our product candidates will be insufficient to support regulatory submissions or marketing approval in the United States and European Union, the risk that we will encounter challenges in the commercial launch of ZYNTEGLO in the European Union, including in managing our complex supply chain for the delivery of drug product or in the adoption of value-based payment models or in obtaining sufficient coverage or reimbursement for our products if approved, the risk that our collaborations, including the collaboration with Celgene, will not continue or will not be successful, and the risk that any one or more of our product candidates, will not be successfully developed, approved or commercialized. For a discussion of other risks and uncertainties, and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, see the section entitled Risk Factors in our most recent Form 10-Q, as well as discussions of potential risks, uncertainties, and other important factors in our subsequent filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and bluebird bio undertakes no duty to update this information unless required by law.

bluebird bio, Inc.Consolidated Statements of Operations(in thousands, except per share data)(unaudited)

For the three months ended September 30,

For the nine months ended September 30,

2019

2018

2019

2018

Revenue:

Collaboration revenue

$

6,575

$

10,926

$

29,310

$

33,971

License and royalty revenue

2,335

602

5,367

1,365

Total revenues

8,910

11,528

34,677

35,336

Operating expenses:

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bluebird bio Reports Third Quarter 2019 Financial Results and Highlights Operational Progress - Business Wire

SCD, HIV Gene Therapy Efforts Get $200M from NIH, Gates Foundation – Sickle Cell Anemia News

The National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation will each invest $100 million over the next four years to speed the development of affordable gene therapies for sickle cell disease (SCD) and the human immunodeficiency virus (HIV) on a global scale.

This unprecedented collaboration focuses from the get-go on access, scalability and affordability of advanced gene-based strategies for sickle cell disease and HIV to make sure everybody, everywhere has the opportunity to be cured, not just those in high-income countries, said NIH Director Francis S. Collins, MD, PhD.

Seventy-five percent of babies born with SCD live in sub-Saharan Africa. It is hoped that experimental gene therapies would advance to clinical trials in the United States and relevant African countries within the next seven to 10 years, and that safe, effective, and inexpensive gene therapies be made available globally, including in low-resource settings where the cost and complexity of these therapies make them inaccessible to many.

In recent years, gene-based treatments have been groundbreaking for rare genetic disorders and infectious diseases, Trevor Mundel, MD, PhD, president of the global health program at the Bill & Melinda Gates Foundation said in a news release.

While these treatments are exciting, people in low- and middle-income countries do not have access to these breakthroughs. By working with the NIH and scientists across Africa, we aim to ensure these approaches will improve the lives of those most in need and bring the incredible promise of gene-based treatments to the world of public health, he added.

Hemoglobin is the protein in red blood cells that binds oxygen, allowing oxygen to be transported around the body. Mutations in the HBBgene, which encodes a component of hemoglobin, result in the formation of sickle hemoglobin that causes sickle cell anemia.

Currently, gene therapies for SCD involves altering the patients own hematopoietic stem cells (bone marrow cells that divide and specialize to produce blood cells including red blood cells). Genes are introduced into the cells using a modified, harmless virus (known as a viral vector). The cells are then transplanted back into the patient where they will produce healthy red blood cells. Gene therapy has an advantage over a bone marrow transplant, as it circumvents the complications associated with a bone marrow donation.

The first goal of the collaboration between the NIH and the Gates Foundation is to develop an easy-to-administer gene-based intervention to correct the mutations in the HBBgene or deliver a functional gene that will promote the production of normal levels of hemoglobin without the need to extract cells from patients and modify them in the lab before introducing the cells back. However, this strategy, known as in vivotreatment, requires the advancement of more efficient delivery systems that can deliver the gene therapy specifically to hematopoietic stem cells.

A second goal of the collaboration will be to work together with African partners and bring potential therapies to clinical trials.

Further research is required to understand the burden of SCD in sub-Saharan Africa and to screen newborns at high risk for the disease, a task that the National Heart, Lung and Blood Institute (NHLBI) has started to tackle by building the necessary infrastructure for clinical research.

The NIH and the Gates Foundation will help boost this infrastructure to allow point-of-care screening (for example, when infants receive vaccinations), and to initiate a standard of care. This will occur outside of the official collaboration.

Our excitement around this partnership rests not only in its ability to leverage the expertise in two organizations to reduce childhood mortality rates in low-resource countries, but to bring curative therapies for sickle cell disease and HIV to communities that have been severely burdened by these diseases for generations, said Gary H. Gibbons, MD, director of the NHLBI.

A persons health should not be limited by their geographic location, whether rural America or sub-Saharan Africa; harnessing the power of science is needed to transcend borders to improve health for all, he added.

Matshidiso Rebecca Moeti, the regional director for Africa at the World Health Organization said, We are losing too much of Africas future to sickle cell disease and HIV.

Beating these diseases will take new thinking and long-term commitment. Im very pleased to see the innovative collaboration announced today, which has a chance to help tackle two of Africas greatest public health challenges, Moeti added.

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

Total Posts: 94

Margarida graduated with a BS in Health Sciences from the University of Lisbon and a MSc in Biotechnology from Instituto Superior Tcnico (IST-UL). She worked as a molecular biologist research associate at a Cambridge UK-based biotech company that discovers and develops therapeutic, fully human monoclonal antibodies.

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SCD, HIV Gene Therapy Efforts Get $200M from NIH, Gates Foundation - Sickle Cell Anemia News

Global Cell Culture Protein Surface Coating Market: What it got next? Find out with the latest research available at ‘The Market Reports’ – Market…

Cell culture is a complex procedure in which cells are grown under controlled physical conditions outside the natural environment. These cells are used to develop model systems for research, study of cellular structure and functions, stem cell research, drug discovery and genetic engineering. Growing scope of cell culture and its applications has led to increased use of protein coated surfaces, as these provide better adhesion and proper nutrition for growth of the cells during cell culture.

Rising investment by government and market players in stem cell research and development activities is one of the major factors driving the cell culture protein surface coatings market. Becton, Dickinson and Company grants a total of USD 100,000 worth reagents every year to 10 scientists pursuing research activities in stem cells. Similarly, the European Union funded four stem cell research projects in its Seventh Framework Program for Research and Technological Development (2007 2013). High funding is leading to extensive stem cell research, resulting in increased use of cell culture protein surface coating products. Moreover, diverse applications of stem cells such as development of bone grafts and artificial tissue would fuel the demand for cell culture protein surface coatings during the forecast period. In addition, increasing cell culture applications in toxicology studies and cell-based assays would boost the demand for protein surface coating products. Currently, 2D cell culture is the most preferred technique by researchers worldwide due to lack of compelling data to switch to 3D cell culture.

The Americas accounted for the majority market share during 2016 and will continue to dominate the market during the forecasted period. The presence of highly developed healthcare infrastructure and the increasing demand for stem cell therapies and regenerative medicines for orthopedics, neurology, and autoimmune therapies are some of the major factors responsible for the markets growth in this region.

Access Report Details at: https://www.themarketreports.com/report/global-cell-culture-protein-surface-coating-market-research-report

The global Cell Culture Protein Surface Coating market is valued at xx million US$ in 2018 is expected to reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025.

This report focuses on Cell Culture Protein Surface Coating volume and value at global level, regional level and company level. From a global perspective, this report represents overall Cell Culture Protein Surface Coating market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.

Key companies profiled in Cell Culture Protein Surface Coating Market report are Corning, EMD Millipore, Thermo Fisher Scientific, Sigma-Aldrich and more in term of company basic information, Product Introduction, Application, Specification, Production, Revenue, Price and Gross Margin (2014-2019), etc.

Purchase this Premium Report at: https://www.themarketreports.com/report/buy-now/1412777

Table of Content

1 Cell Culture Protein Surface Coating Market Overview

2 Global Cell Culture Protein Surface Coating Market Competition by Manufacturers

3 Global Cell Culture Protein Surface Coating Production Market Share by Regions

4 Global Cell Culture Protein Surface Coating Consumption by Regions

5 Global Cell Culture Protein Surface Coating Production, Revenue, Price Trend by Type

6 Global Cell Culture Protein Surface Coating Market Analysis by Applications

7 Company Profiles and Key Figures in Cell Culture Protein Surface Coating Business

8 Cell Culture Protein Surface Coating Manufacturing Cost Analysis

9 Marketing Channel, Distributors and Customers

10 Market Dynamics

11 Global Cell Culture Protein Surface Coating Market Forecast

12 Research Findings and Conclusion

13 Methodology and Data Source

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Global Cell Culture Protein Surface Coating Market: What it got next? Find out with the latest research available at 'The Market Reports' - Market...

Global 3D Cell Culture Markets, 2019-2025: Cancer & Stem Cell Research Displays the Potential to Grow at Over 21.9% – ResearchAndMarkets.com -…

DUBLIN--(BUSINESS WIRE)--The "3D Cell Culture - Market Analysis, Trends, and Forecasts" report has been added to ResearchAndMarkets.com's offering.

The 3D Cell Culture market worldwide is projected to grow by US$2.2 Billion, driven by a compounded growth of 21%.

Cancer & Stem Cell Research, one of the segments analyzed and sized in this study, displays the potential to grow at over 21.9%. The shifting dynamics supporting this growth makes it critical for businesses in this space to keep abreast of the changing pulse of the market. Poised to reach over US$1.9 Billion by the year 2025, Cancer & Stem Cell Research will bring in healthy gains adding significant momentum to global growth.

Representing the developed world, the United States will maintain a 22.6% growth momentum. Within Europe, which continues to remain an important element in the world economy, Germany will add over US$82.5 Million to the region's size and clout in the next 5 to 6 years. Over US$106.9 Million worth of projected demand in the region will come from the rest of the European markets.

In Japan, Cancer & Stem Cell Research will reach a market size of US$135.6 Million by the close of the analysis period. As the world's second largest economy and the new game changer in global markets, China exhibits the potential to grow at 20.5% over the next couple of years and add approximately US$386.3 Million in terms of addressable opportunity for the picking by aspiring businesses and their astute leaders.

Presented in visually rich graphics are these and many more need-to-know quantitative data important in ensuring quality of strategy decisions, be it entry into new markets or allocation of resources within a portfolio. Several macroeconomic factors and internal market forces will shape growth and development of demand patterns in emerging countries in Asia-Pacific.

All research viewpoints presented are based on validated engagements from influencers in the market, whose opinions supersede all other research methodologies.

Competitors identified in this market include:

For more information about this report visit https://www.researchandmarkets.com/r/8wpjwb

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Global 3D Cell Culture Markets, 2019-2025: Cancer & Stem Cell Research Displays the Potential to Grow at Over 21.9% - ResearchAndMarkets.com -...

UCI IN THE NEWS OCT. 25, 2019 – UCI News

Orange County Register, Oct. 25, 2019Hyundai to test self-driving vehicles as shuttle service in IrvineBotRide is being marketed to UC Irvine students, who may not have cars or if they do, struggle to find parking, [Daniel] Han said. The company also is collaborating with researchers in the universitys business and engineering schools. Nick Schaffer, director of external relations for the UCI Paul Merage School of Business, called the collaboration an opportunity for our school and students to be on the forefront of digital transformation. As we prepare our students to be leaders in the digitally driven world, this immersive experience allows them to gain first-hand insight into how technology is disrupting the business landscape. [Subscription required, you can request an electronic copy of the article by sending an email to communications@uci.edu.]

The Stem Cellar, Oct. 25, 2019 (Video)A bridge to the future: training the next generation of stem cell scientistsOne of our recent Bridges graduates is Zach Wagoner. Zach was a biology student and wondering what to do next to help him get some experience for a job when someone told him about the Bridges program. That set him on a course that is changing his life. So how did the random conversation impact Zach? The team at the UC Irvine Sue and Bill Gross Stem Cell Research Center shot this video to answer that question.

The New York Times, Oct. 24, 2019Opinion: The United States Has Never Truly Been a DemocracyIts telling that many of the arguments about the end of democracy suggest its because weve given too much power to the masses, that weve become too democratic. Apaper byShawn Rosenberg, professor of political science and psychological science at the University of California, Irvine,claims that the problem is social media and that other technologies have disrupted the role of elites in guiding the masses through the intricacies of policy and economics. [Subscription required, campus-wide access provided by UCI Libraries. Sign-up here: AccessNYT.com]

Voice of OC, Oct. 25, 2019Cooperative Garden Promotes Food Self-Determination for Santa AnaThey are also setting up an aquaponics system, which UC Irvine donated. Giant plastic tanks sit empty, waiting to hold plants that will grow in water. A separate tank will hold fish, probably tilapia, and the fish waste will be filtered to provide nutrients for the plants. Volunteers from UC Irvine are coming on Nov. 16 to finish setting up the system and the public is invited to come and help.

Daily Pilot, Oct. 24, 2019Double, double toil and trouble a new exhibit on witchcraft opens at UC IrvineA new exhibit on witchcraft and its rise as a feminist identity is opening to the public Friday at the Langson Library at UC Irvine. We Are the Witches You Couldnt Burn tracks the history and evolution of witchcraft between the 16th and 21st centuries. Derek Quezada, outreach and public services librarian for UCI, said inspiration for the exhibit came out of work he was doing with a group of art history students to practice curation based on avant-garde Russian art. [Subscription required, you can request an electronic copy of the article by sending an email to communications@uci.edu.]

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UCI IN THE NEWS OCT. 25, 2019 - UCI News

Mini-brains may already be sentient and suffering, scientists warn – Big Think

Neuroscientists are "perilously close" to crossing serious ethical lines by experimenting with mini-brains that might be complex enough to feel pain. In fact, experiments with mini-brains (also called organoids) might have already crossed those lines.

"If there's even a possibility of the organoid being sentient, we could be crossing that line," Elan Ohayon, the director of the Green Neuroscience Laboratory in San Diego, California, told The Guardian. "We don't want people doing research where there is potential for something to suffer."

On Monday, Ohayon and his colleagues presented a computational study at Neuroscience 2019, the world's largest annual meeting of neuroscientists. The study aimed to establish guidelines for scientists to determine when exactly a mini-brain develops consciousness.

"Assessment informed by the models and associated dynamics suggests that current organoid research is perilously close to crossing this ethical Rubicon and may have already done so," the paper states. "Despite the field's perception that the complexity and diversity of cellular elements in vivo remains unmatched by today's organoids, current cultures are already isomorphic to sentient brain structure and activity in critical domains and so may be capable of supporting sentient activity and behavior."

Mini-brains are tiny lumps of tissue made from stem cells that are capable of generating rudimentary neural activity, and researchers use them in neuroscience experiments. The main benefit of mini-brains is that scientists can conduct important research that sheds light on the human brain all without having to use actual human or animal brains.

As Big Think's Robby Berman noted in March, mini-brains are relatively rudimentary. The most advanced organoid possesses a couple million neurons twice that of a cockroach, but far fewer than an adult zebrafish. The human brain, meanwhile, has some 100 billion neurons. But mini-brains are becoming more complex.

A 2018 study showed that organoids implanted in mouse brains are capable of attaching to the animal's blood supply and sprouting new connections. In another recent study, researchers created a mini-brain with retinal cells, which are the neurons that process visual information. In August, a paper published in Cell Stem Cell described how researchers developed an organoid that is capable of producing brain waves similar to those of premature human babies.

"We never had a brain organoid that can function like the human brain," biologist and researcher Alysson Muotri told Discover Magazine. "The electrical activity of these brain organoids are emitting something we see during normal human development. So, it's a strong indication that what we have should work and function like the human brain."

Some scientists think that mini-brains are still too rudimentary to experience anything like what humans would call pain, and therefore the community doesn't need to worry about creating a nightmarish torture scenario for mini-brains. But others argue that scientists should establish clear guidelines for consciousness so can stop experiments before they effectively create new way for beings to suffer.

"We don't really know actually where this is all going," Patricia Churchland, a Salk Institute professor emerita who studies the linkage between philosophy and neuroscience, told the San Diego Union-Tribune. "It's very, very difficult to predict the future in science, as in baseball."

In the computational study presented on Monday, the researchers discussed five domains through which consciousness might be defined: [1] compositional (e.g., atomic, molecular), [2] causal (e.g., genetic, evolutionary), [3] anatomical (e.g., cellular, network geometry, brain regions), [4] physiological (e.g., cellular, network, whole brain activity), and [5] behavioral (e.g., embodied, virtual). But they also noted a strange and alarming possibility:

"It is important to note that the observations in this computational study point at minimal guidelines and undoubtedly would fail to identify alternate forms of sentience."

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Mini-brains may already be sentient and suffering, scientists warn - Big Think

UK and China scientists developing new drugs to fight Tuberculosis – University of Birmingham

Micky Tortorella (GIBH) speaking at Guangzhou Municipal Government

University of Birmingham scientists have worked with partners in Guangzhou to develop new drugs that can tackle global health epidemics, which have an impact on Chinas rural communities.

Researchers at the University of Birmingham joined forces with their counterparts at the Guangzhou Institutes of Biomedicine and Health (GIBH) to develop a promising hit for anti-Tuberculosis therapy and initiate a drug discovery effort.

In order further to develop the drug and make it available to TB patients, particularly those with drug-resistant strains of the disease, Birmingham and GIBH are working to progress future development of the compounds through the independent spin-out company Legion.

University of Birmingham Vice-Chancellor Professor Sir David Eastwood heard more about the research project from the collaborative team during his recent visit to Guangzhou.

Professor Sir David Eastwood commented: The University of Birmingham is a world leader in molecular chemistry and biosciences, and our partnership with experts at GIBH is making promising progress in the fight against global health epidemics.

We are a global university with a civic outlook and I am delighted that our work with colleagues at GIBH is progressing development on compounds that could help to improve health outcomes for millions of people, particularly in communities across rural China.

The drug discovery effort has been led by Professor John Fossey and Dr Luke Alderwick, Director of the Birmingham Drug Discovery Facility - from the Universitys Schools of Chemistry and Biosciences. At GIBH, the efforts have been headed by Dr Cleopatra Neagoie, chemistry team leader and Micky Tortorella, Director of the Drug Discovery Pipeline.

Professor John S. Fossey commented: We designed and synthesised the first generation of molecules in Birmingham and a team of expert GIBH researchers synthesised and optimised the molecules. Thanks to a wider team involving our postgraduate students, we developed a number of compounds, which have great promise as therapeutic treatments.

Working online has been essential for us - allowing us smoothly to share project data across borders contributing greatly to the success and sustainability of our partnership. We look forward to a new chapter in drug development as GIBHs spinout company progresses our discoveries in China.

Teams based in Britain and China used innovative data sharing technology developed by the University of Birmingham to help them to work faster and more effectively whilst separated by thousands of kilometres.

One of the most important online tools they used is the University of Birminghams BEAR DataShare facility. This allows the team to share project-related data securely across the world even by mobile phone, using a specially developed app.

Resistant TB is an unmet medical need in China and this joint project is very important to the citizens of China. Great things are on the way and we are delighted that our research is now at the point where we can take it to the next level of development, commented Micky Tortorella.

GIBH is a high-profile research institute, run by the Chinese Academy of Sciences, the Peoples Government of Guangdong Province, and the Peoples Government of Guangzhou Municipality. Research areas include stem cell and regenerative medicine, chemical biology, public health, immunology and infectious diseases.

The University of Birmingham has a long-standing relationship with the city of Guangzhou, which is also the sister city of Birmingham itself. The University opened its Guangzhou Centre in 2011 and its China Institute has forged close links with partners in the city and beyond.

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UK and China scientists developing new drugs to fight Tuberculosis - University of Birmingham