National Stem Cell Clinic: Stem Cell Therapy in Miami …

What Are Stem Cells?

The cells in your body have an amazing ability to transform into different types of tissues as required. Some may specialize as muscles, tendons, nerve tissue, or bone. Stem cells are a special type of cell that hasnt specialized yet. These cells are essentially a blank slate, capable of turning into a large number of body tissues.

By harvesting stem cells from your own body, doctors can program these tiny building blocks to become the exact type of tissue you need to heal an injury, be it cartilage for your joints or muscle proteins for repairs.

The first step is to harvest stem cells that are autologous or come from your own body. Bone marrow and fatty adipose tissue contain the largest concentration of stem cells in adults. Once doctors have the correct amount of stem cells, they inject these natural healing factors into the site of your injury along with your blood platelets. This activates the stem cells, causing them to start regenerating damaged tissue.

The possibilities of stem cells for regeneration and repair are virtually limitless, but their effects are especially desirable in areas of the body that were previously believed to be impossible to regenerate, such as cartilage. Here a few situations where stem cell therapy can make a significant difference:

There are a number of reasons why stem cell therapy is so desirable for injury and disease treatment:

At National Stem Cell Clinic (NSCC), we stay at the cutting edge of stem cell treatment. Here are two excellent treatment possibilities using autologous stem cells.

As a high-tech medical care clinic with top surgeons with extensive experience in cutting-edge medical treatments, we offer the most advanced regenerative tissue therapy available. At National Stem Cell Clinic, our expert physicians explain all treatment options available to you, as well as the benefits of each for reaching your personal recovery goals.

With an astonishing 95 percent success rate, we can help athletes make a quick recovery and keep going strong in their career. Stem cell therapy can also provide lasting pain relief for people with arthritis or other chronic pain conditions. To schedule an appointment or request additional information, reach out to us by phone or online.

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In the clinic for Aug. 6, 2020 | 2020-08-06 – BioWorld Online

Company Product Description Indication Status Phase I Dicerna Pharmaceuticals Inc., of Lexington, Mass. RG-6346 RNAi targeting hepatitis B virus mRNA Chronic hepatitis B virus infection In group C, 9 of 10 participants who received RG-6346 and a nucleoside analogue and completed the treatment period achieved 1 log10 IU/mL reduction in hepatitis B surface antigen (HBsAg) at day 112; mean reduction in HBsAg at day 112 was 1.39 log10 IU/mL for the 1.5-mg/kg dose, 1.80 log10 IU/mL for the 3-mg/kg dose and 1.84 log10 IU/mL for the 6-mg/kg dose Dicerna Pharmaceuticals Inc., of Lexington, Mass. Nedosiran RNAi targeting lactate dehydrogenase Primary hyperoxaluria 1, 2 and 3 (PH1, PH2 and PH3) In the Phyox3 open-label extension, 8 of 8 patients with PH1 achieved normalization or near-normalization urinary oxalate levels (Uox) at day 120 with a mean Uox of 0.404 mmol/1.73m2 BSA/24 hr; 1 of 3 patients with PH2 achieved normalization of Uox Personalized Stem Cells Inc., of Poway, Calif. PSC-01 Adipose-derived stromal vascular fraction cells Knee osteoarthritis Completed enrollment in the study; data expected by the end of 2020 Precigen Triple-Gene, a unit of Precigen Inc., of Germantown, Md. INXN-4001 Nonviral plasmid expressing SDF-1alpha, VEGF165 and S100A1 Chronic heart failure Half of the 10 patients had a 5-point improvement in their total KCCQ score 6 months after treatment; 4 of 8 evaluable patients had a >50-meter improvement in their 6-minute walk time at 6 months Tessa Therapeutics Pte Ltd., of Singapore CD30 CAR T Autologous cell therapy Relapsed/refractory Hodgkin lymphoma For the 41 patients, 1-year survival was 94% in phase I/II study; of patients with complete responses, 61% had no evidence of recurrence after 1 year Phase II Bioaegis Therapeutics Inc., of Morristown, N.J. rhu-pGSN Recombinant human plasma gelsolin Hospitalized patients with severe COVID-19 pneumonia Enrolled first patient in study testing 3 doses of the drug; primary endpoint is survival without organ failure and without mechanical ventilation, vasopressors or dialysis on day 14 Idorsia Pharmaceuticals Japan, unit of Idorsia Ltd, of Allschwil, Switzerland Daridorexant Dual orexin receptor antagonist Insomnia In dose-confirmation study in 47 adults in Japan, study drug showed dose-dependent decrease in wake after sleep onset (WASO) at day 1 and 2 and decreased latency to persistent sleep in dose-dependent manner; improvements seen on measures such as subjective WASO, subjective latency to sleep onset and subjective total sleep time Medicinova Inc., of La Jolla, Calif. Ibudilast (MN-166) Phosphodiesterases 4 and 10 inhibitor Alcohol use disorder Drug reduced the number of heavy drinking days compared to placebo (p=0.03) and attenuated alcohol cue-elicited activation in the bilateral ventral striatum (p=0.02) Nordic Nanovector ASA, of Oslo, Norway Betalutin CD37-targeting antibody-radionuclide conjugate Relapsed/refractory follicular lymphoma Independent review committee recommended company focus on the 15-MBq/kg Betalutin dosage arm and discontinue the 20-MBq/kg dose Phase III Boehringer Ingelheim International GmbH, of Ingelheim, Germany Ofev (nintedanib) Tyrosine kinase inhibitor Chronic fibrosing interstitial lung diseases with a progressive phenotype In the Inbuild study, at 52 weeks, 43.4% of patents taking Ofev had a >5% absolute decline in forced vital capacity (FVC), compared to 55% of patients taking placebo; >10% FVC was seen in 28.3% and 36.6% of patient taking Ofev and placebo, respectively Levo Therapeutics Inc., of Chicago LV-101 (intranasal carbetocin) Oxytocin-receptor agonist Prader-Willi syndrome Primary endpoint for the 9.6-mg dose of LV-10 was not met; 3.2-mg dose improved the Hyperphagia Questionnaire for Clinical Trials (HQ-CT) score (p=0.016); HQ-CT scores for combined doses produced a p-value of 0.055; 3.2-mg dose also improved clinical global impression of change (p=0.027) and the PWS Anxiety and Distress Behaviors Questionnaire (p=0.027) Novartis AG, of Basel, Switzerland Ofatumumab Monoclonal antibody targeting CD20 Relapsing forms of multiple sclerosis Data published in The New England Journal of Medicine showed drug reduced annualized relapse rate by 51% and 58% compared to teriflunomide in the Asclepios I and II studies, respectively (p<0.001 for both); drug reduced risk of confirmed disability worsening at 3 months by 34% (p=0.002) and at 6 months by 32% (p=0.01) Rafael Pharmaceuticals Inc., of Cranbury, N.J. CPI-613 (devimistat) Targets the mitochondrial tricarboxylic acid cycle Metastatic pancreatic cancer Completed target enrollment of 500 patients in the Avenger 500 study

Notes

For more information about individual companies and/or products, see Cortellis.

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In the clinic for Aug. 6, 2020 | 2020-08-06 - BioWorld Online

Cell Therapy Manufacturing Market to be Worth USD 8 billion by 2030, predicts Roots Analysis – Bulletin Line

Roots Analysis has announced the addition of Cell Therapy Manufacturing Market (2nd Edition), 2018-2030 report to its list of offerings.

Natasha Thakur, the principal analyst, stated, The growing number of cell therapy candidates continues to create an increasing demand for facilities that offer manufacturing services for these complex pharmacological interventions. Presently, over 145 companies / organizations are actively offering manufacturing services for such products. The installed global manufacturing capacity is estimated to be over 1 billion sq ft, with the maximum capacity available in North America

The report presents opinions on several key aspects of the market. Among other elements, it includes:

The report features inputs from a number of eminent industry stakeholders. Thakur remarked, Most of the experts we spoke to confirmed that the manufacturing of cell therapies is largely being outsourced due to exorbitant costs associated with setting-up such facilities. The report features detailed transcripts of discussions held with the following experts:

The research also includes detailed profiles of the following players:

For additional details, please visithttps://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing-market-2nd-edition-2018-2030/209.hl or email [emailprotected]

Contact:

Gaurav Chaudhary

+1-604-595-4954

Link:
Cell Therapy Manufacturing Market to be Worth USD 8 billion by 2030, predicts Roots Analysis - Bulletin Line

StemCells 21 Premium Stem Cell Treatments In Bangkok …

We organize our stem cell packages based on the size and complexity of your condition. Small, simple conditions require relatively few stem cells to treat them. Large, complicated conditions or conditions you wish to treat as quickly and as completely as possiblewill require larger volumes of stem cells to get the job done.

We currently offer four stem cell packages.

Condition Level

Treatment Type

Stem Cell Volume

I

Single Area of Focus & Treatment

50,000,000 stem cells

II

Multiple Areas of Focus, Simple Inflammatory Conditions, or Early Stage Disease

100,000,000 stem cells

III

Complex Conditions or Premium Option for Simple Conditions

200,000,000 stem cells

IV

Advanced Stage Disease or Fastest Possible Treatment for All Conditions

300,000,000+ stem cells

We select your supportive therapies based on your condition. Your supportive therapies will direct your stem cells to the impacted tissue that needs to be regenerated, trigger selective cell activity, and provide your body with additional biological building blocks to deliver a faster and more complete regeneration.

We offer many supportive therapies, that include but are not limited to:

We curate an additional set of simple supportive therapies that you will bring home with you after your treatment, and self-administer for one to three months. This take home set ensures that your stem cells and your impacted tissue continue to receive direction and building blocks to continue to regenerate after your initial treatment.

We typically provide a one to three-month supply of:

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‘Year of Preparations for the Next Fifty Years’ will contribute to country’s development process – WAM EN

ABU DHABI, 3rd August, 2020 (WAM) -- In 2020, the UAEs achievements, most notably the launch of the Hope Probe to Mars and the operation of Unit 1 of the Barakah Nuclear Power Plant, have proven that the "Year of Preparations for the Next Fifty Years" will significantly contribute to the countrys development process.

Despite the difficult circumstances facing the world caused by the coronavirus, COVID-19, pandemic, the UAE has succeeded in turning challenges into opportunities for innovation and development, which is reflected in its approach to limiting the spread of the virus through a range of creative measures, such as developing technology to discover the virus using lasers that generate results in a record time, using stem cell therapy for patients, and participating in global efforts to find a vaccine.

In 2020, the UAEs achievements reflect the national ambitions and wisdom of its leadership. The Hope Probe project involved nearly 200 Emirati engineers and researchers, who worked hard for six years to fulfil the UAE's dream to reach the Red Planet.

The Barakah Nuclear Power Plant also highlights the UAEs efforts to build the capacities of national cadres in this sector. Nearly 244 employees work for the Federal Authority for Nuclear Regulation, FANR, with 67 percent being Emiratis, of which 45 percent are in leading and managerial positions. Women also account for over 40 percent of the Authoritys employees.

Once all four units of the plant are commercially operating, the UAE's Barakah Nuclear Energy Plant will produce up to 25 percent of the country's electricity requirements while in parallel preventing the release of 21 million tons of carbon emissions each year.

On the level of combating COVID-19, Emirati national cadres and institutions joined the front line since the first day to discover the first case in the country, and contributed to achieving milestones at the global level.

In May, a patent was granted by the Ministry of Economy for the development of an innovative and promising treatment for COVID-19 infections using stem cells. The treatment was developed by a team of doctors and researchers at the Abu Dhabi Stem Cell Center, ADSCC, and involves extracting stem cells from the patients own blood and reintroducing them after activating them.

QuantLase Imaging Lab, the medical-research arm of the Abu Dhabi Stock Exchange-listed International Holdings Company, IHC, announced that it has developed novel equipment which enables for much faster mass screenings, with test results available in seconds and allowing testing on a wider scale.

The technology will reinforce the UAEs position as a hub of research and innovation, as scientists around the world scramble to devise a faster method of testing for patients suspected to have been infected with the coronavirus and potentially identifying carriers before they become infectious.

The first World Health Organisation, WHO, enlisted global clinical Phase III trial of Sinopharm CNBGs inactivated vaccine to combat COVID-19 started in Abu Dhabi.

The worlds first Phase III trial is the result of a cooperation partnership between Abu Dhabi based G42 Healthcare, currently at the forefront of the battle against COVID-19 in the UAE, and Sinopharm CNBG, the worlds sixth-largest vaccine manufacturer, ranked 169th on the Fortune Global 500 list of 2018.

The trials are being operated by health practitioners from Abu Dhabi Health Services, SEHA, who are providing facilities at five of their clinics in Abu Dhabi and Al Ain in addition to a mobile clinic to ensure the trials are readily accessible to volunteers participating in the programme.

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'Year of Preparations for the Next Fifty Years' will contribute to country's development process - WAM EN

MediVet Biologics Rebrands as Ardent Animal Health – PR Web

Ardent Animal Health

LEXINGTON, Ky. (PRWEB) August 03, 2020

Introducing Ardent Animal Health MediVet Biologics rebrands company and positions its platform of innovative products for transformative growth

MediVet Biologics is announcing a new name and a new look for its corporate brand as it relaunches itself as Ardent Animal Health.

In the years since its inception in 2016, the new Ardent Animal Health has developed into a global leader in the areas of veterinary regenerative medicine and oncology solutions for animals. The companys core mission is to develop affordable, innovative treatments for animal cancer and disease while supporting its veterinary partners in their efforts to make a positive impact on pet health.

The name Ardent captures the spirit of our organization as a company with fiery passion for innovation guided by compassion for the well-being of animals. The new brand translates the enormous and unique impact our veterinarian customers make each day in the lives of their patients. Our aim is to leverage our brand to accelerate connecting pet owners seeking advanced care to our expanding network of progressive veterinarian partners around the world," says Thomas Masterson, President of Ardent Animal Health.

Under its former brand of MediVet Biologics, Ardent Animal Health developed the first in-clinic adipose regenerative stem cell therapy kit, ActiStem Therapy. A major scientific advancement in animal regenerative medicine, the product offers an economic solution for owners of pets suffering from osteoarthritis, hip dysplasia, and ligament and cartilage injuries, as well as numerous mobility ailments. In addition to regenerative cells from fat, Ardent-certified hospitals offer other biologic treatments such as Platelet Rich Plasma, or PRP, a blood-derived treatment gaining popularity in human sports medicine.

Ardent Animal Health is unique for a company of its size, as it has surrounded its current and pipeline products with strong intellectual property and multiple collaborative university studies. This has allowed the company to grow, cementing its current technology, and look toward the future for its stem cell-based product pipeline candidates. Ardent Animal Health will launch with an extensive following of pet owners and veterinarians positively impacted by its products and services. The studies, passionate customers, and patient outcomes continue to provide momentum for the companys technology and products. Over 20,000 veterinary patients have received treatment of an Ardent Animal Health regenerative product or service.

Ardent Animal Health has also introduced cutting edge science to fight against canine cancer with its cancer vaccine service, K9- ACV, an immunotherapy vaccine generated from a canine patients own cancerous tumor. K9-ACV is designed to stimulate the canine patient's immune response to attack the cancer. We are looking to meet an unmet need in pet cancer, at the family veterinarian office when needed. 50% of dogs over the age of ten will develop some type of cancer, so there is a need for a broadly applicable approach that can improve lifespan at a reasonable cost. Our preliminary studies and extensive market research indicate this approach will provide access to pets that need it, Masterson said.

According to Mr. Masterson, the companys strength in these core innovative therapeutic areas will allow the organization to accelerate growth following its recent transition in both leadership and ownership. As a portfolio company of STUCK Fund 1, based in Milwaukee, WI, Ardent Animal Health will continue to develop novel approaches for early disease detection and treatments, with a focus on precision medicine for pets in need.

We will continue to focus much of our strategy in creating novel products and services utilized in veterinary hospitals. We believe that this approach is key to the future of animal health. It is important not only for value creation but to ensure veterinarians have the ability to diagnose and treat their patients with the same leading-edge strategies underway in human health. Our animal family members deserve it.

Disclaimer Experimental Cancer Vaccines created by Ardent Animal Health are provided under 9 CFR 103.3 via USDA Center for Veterinary Biologics oversight for use under supervision/prescription of a licensed veterinarian. Safety & efficacy have not been yet established.

About Ardent Animal Health

Since 2016 Ardent Animal Health based near Lexington, KY, has provided advanced medical strategies to veterinary hospitals around the world. Ardent provides regenerative medicine treatments such as ActiStem Therapy and PureVet PRP to veterinarians for pain and disease in companion and equine patients. Additionally, Ardent Animal Health is pursuing advanced strategies for detection and treatment of canine cancer. Through creation of its own intellectual property and strategic licensing partners, the companys portfolio includes current and future offerings aimed to raise the standard for animal healthcare.

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About STUCK Fund 1

Ardent Animal Health represents an innovation-focused element of the STUCK Fund 1 portfolio, as Ardent competes in the fast-growing and recession-resistant pet health sector. STUCK Fund 1, based in Milwaukee, WI, was founded in 2014 to live out the lessons the investment firms founders learned from growing its business into an international, $100 million organization. STUCK founders were honored with numerous accolades in their prior ventures, including the Muskego Manufacturing Business of the Year award and the Waukesha Business Alliance Manufacturing Business of the Year honor, among several others. Currently, the investment firm supports like-minded entrepreneurs to accelerate and sustain the growth of their businesses.

About

Media Contact: Matt Yeich (859)885-7111 matt@ardentanimalhealth.com

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27th Annual Luau and Legends of Surfing Invitational Set to Make Virtual Waves – UC San Diego Health

Participants gather for a group photo at the 2019 Luau and Legends of Surfing Invitational.

For the first time ever, surfers, scientists, physicians and survivors will come together virtually to support the fight against cancer at the annual Luau and Legends of Surfing Invitational on Aug. 9.

As UC San Diego events are being canceled or postponed because of the coronavirus pandemic, the annual fundraiser has transitioned to a virtual format to allow participants to support the fight against cancer from home.

Instead of surfing the ocean, participants are invited to surf the wave of cancer research as they Crowdsurf for a Cure, helping raise money for research, education and clinical care. All proceeds from the 27th annual Luau and Legends of Surfing Invitational will benefit Moores Cancer Center at UC San Diego Health and contribute to the Campaign for UC San Diego.

As we celebrate the 27th Luau and Legends of Surfing Invitational, it is inspiring to see the local community continue to support the breakthrough discoveries and life-saving treatment developed by Moores Cancer Center, said Dr. Scott M. Lippman, director of Moores Cancer Center at UC San Diego Health. While we cannot join together in person for this years event, cancer does not stop during the COVID-19 pandemic and neither does our commitment to finding new cures and treatments for this life-threatening disease. Thanks to the generous donations raised through the Luau, we can continue to provide our patients with the latest individualized treatment and excellence in patient care that is only available at an academic medical center like ours.

Sandra Dillon and Casey Turk. Photo Courtesy of Sandra Dillon.

The beloved fundraiserwhich has traded tuxedos for wet suits and ballrooms for beach views since its founding in 1993has brought in nearly $10 million for research and helped thousands of cancer patients through clinical trials, new treatments and delivering discoveries. Now, amid nationwide pandemic-related disruptions to the health sector, support towards ending this devastating disease continues to be critical.

For myelofibrosis patient and advocate Sandra Dillon, this support made all the difference in her journey with cancer. When doctors discovered a small lump behind Dillons ribcage in 2004which turned out to be an enlarged spleen, a symptom of myelofibrosisit came completely out of the blue. As a healthy 28-year-old, the last thing she expected was to be diagnosed with an extremely rare cancer with no real treatment options and a median survival rate of five to seven years.

What I thought was my whole life ahead of me was now just a few years, said Dillon, whose doctors tried to manage her symptoms as she slowly got sicker from the disease. I had such a hard time with my diagnosis and my experience. Knowing that there was no treatment that could stop myelofibrosis, I just didn't want to see doctors, be in a hospital or take any more tests. I kind of gave up on medicine in general and figured, Well, Ill just take the time that I've got left and that's all I've got.

Several years later, the trajectory of Dillons life changed completely when she moved to San Diego and was introduced to the team at Moores Cancer Center. Ridden with fear and hesitancy, she made the courageous decision to continue to fight for her life with support from her friends and husband, Casey Turk.

What I found at Moores Cancer Center was the exact opposite of what I was expecting. I was greeted with so much compassion and care at every level, said Dillon, who came to the center in 2011. Initially, I was afraid of being a pin cushion and just a number passing through a system. Instead, I found a home. Moores Cancer Center is a shining light of what treatment and health care can, and should, look like.

Dr. Catriona Jamieson

At Moores Cancer Center, Dillon met physician-scientist Dr. Catriona Jamieson, Deputy Director of Moores, who enrolled her in a clinical trial for a new drug called fedratinib designed to block cancer cell proliferation. The results were amazingin a few months, Dillon was revitalized with newfound energy, less pain and a whole new life.

However, when the promising cancer drug was discarded for safety concerns and its trial pulled, Jamieson and her team were forced to turn to alternate trials and treatments to halt Dillons disease. With the health of multiple patients depleting in the absence of fedratinib, Jamieson worked tirelessly alongside scientist, biotech executive and Moores Cancer Center Board Vice Chair John Hood, who has a doctorate in medical physiology and led early research on the drug, to fight to bring it back. When fedratinib was finally approved by the FDA in 2019, it was the first new therapy approved for myelofibrosis in nearly a decade. It is now available under the brand name Inrebic.

John Hood

Now that I am on the drug, I havent had to have a blood transfusion in over a year. I feel incredible again, said Dillon. What Dr. Jamieson and Hood have accomplished is incredibleits a blessing for me and an amazing testament to what is possible.

During the online fundraiser on Aug. 9, Jamieson and Hood will both be recognized with the Rell Sunn Award, which honors the memory of Rell Kapoliokaehukai Sunn, known as the First Lady of Surfing. Sunn was diagnosed with breast cancer at the age of 32, but rather than submitting to the disease, she lived life to the fullest until passing 15 years later in 1998. The Rell Sunn Award recognizes individuals who have made a difference in the battle against cancer and who embody the Aloha spirit.

This event has had a sustainably positive impact on our relentless drive to deliver new discoveries to the clinic with alacrity, and our unique capacity at Moores Cancer Center to develop personalized cancer stem cell, immunotherapy, and precision-medicine-guided targeted therapies for hopeful patients across economic strata, said Jamieson. To receive this award is such an extraordinary privilege considering that it honors Rell Sunn, a champion Hawaiian surfer who battled breast cancer and was the personification of hope, joy and the spirit of ganbatte, which is the Japanese word for never, ever, ever, give up.

Being honored based on a person like Sunn, by your peers and neighbors, is incredible. I feel very grateful for it, said Hood. I hope what we didfacing down the FDA with a small group in the company and doing everything we can to get it to the patientswould make her proud.

The virtual luau festivities kick off online on Aug. 9 at 5 p.m. Guests can expect to enjoy a program featuring: an address from Chancellor Pradeep K. Khosla, Vice Chancellor for Health Sciences Dr. David Brenner and CEO of UC San Diego Health Patty Maysent, messages from surf legends, Moores Cancer Center leaders, Polynesian dancers, live music and more. Attendees in the local region can also join in by pre-ordering a Dinner and Drinks packagea catered meal and cocktails with options to be picked up or delivered to their home to enjoy during the event. Featured artwork will be presented by Southern California surfer Andy Davis.

The Luau and Legends of Surfing Invitationals Crowdsurf for a Cure is free to register and to attend. Event sponsors include: Cooley LLP; Lina and Christian Waage; Lisa and Mike Rhodes; Valerie Ewell Armstrong and Sam Armstrong; BioMed Realty; ASML; Arey Jones; The Allergan Foundation; and Pfizer. For more information about sponsorship opportunities and event activities, visit the Luau and Legends of Surfing Invitational website. You can also get read more about the Moores Cancer Center at UC San Diego Health.

Gifts made through the 27th annual Luau and Legends of Surfing Invitationals Crowdsurf for a Cure also contribute to the Campaign for UC San Diegoa university-wide comprehensive fundraising effort concluding in 2022. Alongside UC San Diegos philanthropic partners, the university is continuing its nontraditional path toward revolutionary ideas, unexpected answers, lifesaving discoveries and planet-changing impact. For more information, visit campaign.ucsd.edu.

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27th Annual Luau and Legends of Surfing Invitational Set to Make Virtual Waves - UC San Diego Health

Celsius Therapeutics, Twist Bioscience, And More: News From July 2020 – Bio-IT World

July 30, 2020 |July featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including Celsius Therapeutics, Twist Bioscience, and more.

Celsius Therapeuticsannounced the signing of three collaboration agreements with the University of Oxford, Cleveland Clinic, and the LMU University Hospital Munich. In each agreement, Celsius will partner with leading academic scientists to access patient tissue samples and apply its proprietary single-cell genomics platform and machine learning capabilities to discover new insights into inflammatory bowel disease (IBD). Under these collaborations, Celsius will evaluate a large number of longitudinal (both pre- and post-treatment) samples, including biopsies from patients who respond to or fail anti-TNFa therapy (University of Oxford); Crohns disease patients who develop disease recurrence following intestinal resection (Cleveland Clinic); and children with very early onset IBD (LMU University Hospital Munich). Celsius will integrate single-cell RNA sequencing data from these samples with clinical data provided by its partners to identify novel drug targets and patient stratification approaches for specific patient subsets. Under the terms of each agreement, Celsius retains the ability to incorporate both the de-identified clinical information and longitudinal single-cell genomics data generated from these studies into its large and continuously growing database. Celsius plans to combine the knowledge generated by these agreements with other work using its single-cell genomics and machine learning algorithms to elucidate this complicated disease biology. Further, Celsius will combine these insights with orthogonal data sets derived from functional genomics and other approaches to verify biological mechanisms and validate potential drug targets. Press release

Twist Bioscienceannounced a partnership withTakeda for access to proprietary phage display libraries for the discovery, validation and optimization of antibodies in Takedas pipeline of biologics for oncology, rare diseases, neuroscience, and gastroenterology. Under the terms of the agreement, Twist Biopharma, a division of Twist Bioscience, will license to Takeda its Library of Libraries, a panel of synthetic antibody phage display libraries derived only from sequences that exist in the human body. Together, the companies will work to discover, validate and optimize new antibody candidates. In return, Takeda will pay Twist annual technology licensing fees, as well as milestones and royalties for all compounds discovered from the Twist phage display libraries. We look forward to applying our unique ability to generate robust, diverse and cutting-edge libraries together with Takedas deep insight into therapeutic drug discovery and development to truly forge new frontiers in bringing personalized therapies to patients worldwide, Emily M. Leproust, CEO and co-founder of Twist Bioscience, said in an official statement. Press release

LabVantage Solutionsannounced that the newly-released 8.5 edition of its LabVantageplatform offers a fully integrated Scientific Data Management System (SDMS). LabVantage SDMS ensures security and control against data loss or modification. The optional SDMS seamlessly interfaces with all elements of the LabVantage platform, including LIMS (laboratory information management system), ELN (electronic laboratory notebook), and LES (laboratory execution system). LabVantage 8.5 also includes a new and comprehensive Configuration Management and Transfer (CMT) feature for greater LIMS administration productivity and better control, along with a number of enhancements that make the LabVantage ELN easier to use. During these challenging times, we are especially proud to release LabVantage 8.5, which represents a major advance reflecting our commitment to making the advantages of digital transformation fully accessible to our customers, said John Heiser, CEO of LabVantage, in a press release. LabVantage 8.5s fully integrated SDMS is specifically designed for the LabVantage platform and provides major benefits to laboratory managers, with the aim of making their operations more efficient, productive, and secure. Our user-friendly, all-in-one SDMS offers seamless, continuous data integrity. Importantly, it allows managers to secure all of their data, not just the final results. The integrated SDMS automatically collects and protects all instrument and other relevant laboratory data as it is generated, which provides a rich informatics and analytical resource that enables better lab management, improved quality, and enhanced security. Full integration means that all relevant lab-generated data is collected automatically and rapidly made available to laboratory staff. Importantly, integration ensures data integrity and security by eliminating the need to transfer data between system components or to leave it with the instrument system, typically a weak link in the process. Press release

The Josep Carreras Leukaemia Research Institutehas created the OneChain Immunotherapeutics (OCI)spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis. The spin-off is being funded initially through a round of seed capital provided by Invivo Ventures, the Ministry of Industry, through CDTI-Innvierte, and the Josep Carreras Foundation, and it clearly makes the case for bringing the research carried out by Dr. Pablo Menndez's group closer to patients. Dr. Mendez is an ICREA research professor and the scientific director at the Josep Carreras Leukaemia Research Institute's Hospital Clnic-UB Campus. "OCI is the vehicle that will enable us to take all the work we have been doing over all these years and apply it to clinical use, Dr. Menndez said in an official statement. At the academic level it is very complicated to develop these strategies and manage all the regulatory mechanisms associated with the development of a product. OCI will enable us to carry out all the necessary steps so that all our knowledge can be available to patients." Press release

VantAIand TARA Biosystemsannounced the launch of a biology-driven, AI-enabled collaboration for accelerated cardiac drug development. The partnership will leverage TARAs state-of-the-artin vitrohuman biology models and VantAIs leading computational drug discovery capabilities to identify and develop new therapies to fight cardiac disease. Combining the power of VantAIs machine learning-enabled gene-disease mapping techniques with the rich, high-fidelity phenotypic data generated from TARAsin vitrohuman cardiac disease models, TARA and VantAI will identify novel drug targets linked to cardiac disease. Then, the team will use VantAIsin silicoplatform to produce novel molecules that effectively modulate these targets, many of which have been previously considered undruggable. VantAIs platform will prioritize modality strategies and use generative approaches to design precise chemistry that is effective while also displaying favorable pharmaceutical properties. The functional response of these novel molecules will then be evaluated in TARAs induced pluripotent stem cell-derived human cardiac tissue models, which include a repertoire of healthy, gene-edited, patient-derived, and drug-induced phenotypes of human disease. The TARA models represent a highly versatile platform for capturing robust physiologic endpoints of human cardiac function, including contractility, electrophysiology, calcium signaling, structure, as well as genomic, proteomic, and metabolic profiles. These comprehensive experimental results will be fed back to VantAIsin silicoplatform to both power further refinement of lead candidates and expand the VantAI-TARA joint data graph view of cardiac disease systems. Press release

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Celsius Therapeutics, Twist Bioscience, And More: News From July 2020 - Bio-IT World

David Karli Launches New Treatment for Patients with severe Arthritic Conditions – THISDAY Newspapers

Colorado-based doctor, David Karli, has announced the launch of a new bone marrow-derived stem cell injection program for patients with arthritic conditions and both acute and chronic soft tissue disorders of muscle, tendon and ligament.

The Elizabethtown College graduate is a former Chief Resident of the Harvard Medical School Department of Physical Medicine & Rehabilitation and runs a fitness programme for enterpreneurs with hectic schedules.

Dr Karlis avid interest in regenerative medicine and the development of non-surgical interventions for a variety of conditions has led to the development of Platelet Rich Plasma (PRP, Platelet Gel) and Bone Marrow Stem Cell injection therapy programs for patients with acute and chronic musculoskeletal injuries.

His work with The Steadman Clinic has lead to pioneering work in developing safe and effective use of biologics in orthopaedic medicine for both surgical and non-surgical applications.

A Diplomate of the American Board of Physical Medicine and Rehabilitation, Dr. Karli also maintains active membership in multiple professional societies. He was a recent co-investigator in the first Level I randomized, double-blind, placebo-controlled clinical trial researching the efficacy of PRP in chronic tennis elbow, a landmark study slated for publication in the American Journal of Sports Medicine.

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David Karli Launches New Treatment for Patients with severe Arthritic Conditions - THISDAY Newspapers

Dreambody.clinic – Stem Cells, HGH, TRT, Hormone …

Mesenchymal Stem Cell Therapy

At Dream Body Clinic we offer Mesenchymal Stem Cell Therapy Treatments for Autoimmune disorders, Chronic Degenerative disorders, Articulations, Cosmetic Issues and more.

Our Mesenchymal Stem Cells are derived from Umbilical cord (Wharton Jelly) and Placenta. All donors are under 30 years old and put through a stringent screening process to ensure we only have gold quality stem cells. This tissue that we derive from is the youngest possible source for stem cells. This means that the stem cells we administer are as young and healthy as possible. There is no chance of rejection as mesenchymal stem cells lack human leukocyte antigen (HLA). HLA is what the immune system looks for to detect intruders. Our stem cells are sourced in the best way possible and then cultivated to provide the tens of millions or hundreds of millions of stem cells needed for a successful stem cell therapy.

Our Mesenchymal Stem Therapy Treatments have many anti-aging benefits. We are able to effect the whole body with a stem cells anti-aging IV Treatment or focus on specific areas like the face or hair. The stem cells target inflammation and then fix the route cause. Chronic inflammation always speeds up aging so this is the first way anti-aging stem cells effect. Next they donate mitochondria to weak cells. The mitochondria are like the engines of the cells and by having fresh, new mitochondria they have more energy and work better. The stem cells have also been found to extend telomere length in at least 6 types of cells. It is believed that research will show they do this for even more cells. The stem cell facial treatment is able to restore collagen and fat below the surface of the skin. This fills in the lines and restores a youthful appearance. It also improves skin quality and thickness. The Stem Cell Hair Restoration Treatment allows hair follicles that are closing to re-open. They also help regenerate the existing hair. stem cell therapy for anti-aging is wonderful

Our Diabetes Stem Cell Treatment is extremely effective at mitigating the negative effects of Type 2 diabetes. The mesenchymal stem cell treatment for Type 2 diabetes is an IV of 300 Million mesenchymal stem cells. These stem cells send out cytokines that effectively reprogram the immune system to protect the pancreas instead of attacking it. This leads to stabilized blood glucose levels and proper insulin response. A proper diet with low sugar and low fast carbohydrates is needed to maintain results, but the stem cell treatment has a profound effect on Type 2 diabetes. Learn more about our Type 2 Diabetes Stem Cell Therapy.

Our Lyme Disease Stem Cell Treatment is extremely effective at mitigating the negative effects of Lyme disease. The mesenchymal stem cell treatment for Lyme disease is an IV of 300 Million mesenchymal stem cells. These stem cells send out cytokines that effectively reprogram the immune system to protect the body instead of attacking it. This leads to feeling normal again. Learn more about our Lyme Disease Stem Cell Treatment.

Our HGH Legal Fly & Buy Program is our longest running program that we have been doing for 8 years. It is legal to seek medical treatment abroad and return home with any prescribed medication. We start with a blood panel to make sure you are healthy and then prescribe the HGH to meet your country of origins law. For the USA that is 50 dose units and the rest of the world is a 90 day supply. We can legally send you home with up to 720 IU of pharmaceutical HGH like Norditropin HGH, Genotropin HGH or Humatrope HGH. That is enough for 2IU a day for a year. Learn more about our HGH Legal Fly & Buy Program.

Our Genotropin HGH Legal Fly & Buy Program is the best. We can legally send you home with up to 720 IU of Genotropin HGH. Enough for 2IU a day for a year. Buy HGH the legal way. Learn more about our Genotropin HGH Legal Fly & Buy Program.

Our Norditropin HGH Legal Fly & Buy Program is the best. We can legally send you home with up to 720 IU of Genotropin HGH. Enough for 2IU a day for a year. You can now buy HGH Legally! Learn more about our Norditropin HGH Legal Fly & Buy Program.

Our Humatrope HGH Legal Fly & Buy Program is the best. We can legally send you home with up to 720 IU of Humatrope HGH. Enough for 2IU a day for a year. You can finally buy HGH Legally! Learn more about our Humatrope HGH Legal Fly & Buy Program.

Our Testosterone Replacement Therapy TRT Legal Fly & Buy Program is the best. We can legally send you home with up to 100ml of Testosterone. That is enough to last 2 years at 1ml a week. You can finally buy TRT at the dose you want Legally! Learn more about our Testosterone Replacement Therapy TRT Legal Fly & Buy Program.

Our Proviron Legal Fly & Buy Program is the best. We can legally send you home with up to 80 boxes of proviron. You can finally buy Proviron at the dose you want Legally! Learn more about our Proviron Legal Fly & Buy Program.

Our Deca Durabolin Legal Fly & Buy Program is the best. We can legally send you home with up to 50 boxes of Deca Durabolin. You can finally buy Deca Durabolin at the dose you want Legally! Learn more about our Deca Durabolin Legal Fly & Buy Program.

Our Anavar (Oxandralone) Legal Fly & Buy Program is the best. We can legally send you home with up to 6 bottles of Anavar (Oxandralone). You can finally buy Anavar (Oxandralone) at the dose you want Legally! Learn more about our Anavar (Oxandralone) Legal Fly & Buy Program.

Our Modafinil Legal Fly & Buy Program is the best. We can legally send you home with up to 8 boxes of Modafinil. You can finally buy modafinil at the dose you want Legally! Learn more about our Modafinil Legal Fly & Buy Program.

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Dreambody.clinic - Stem Cells, HGH, TRT, Hormone ...