Groundbreaking hip and stem cell surgery in Southampton

PUBLIC RELEASE DATE:

16-May-2014

Contact: Becky Attwood r.attwood@soton.ac.uk 44-023-805-92116 University of Southampton

Doctors and scientists in Southampton have completed their first hip surgery with a 3D printed implant and bone stem cell graft.

The 3D printed hip, made from titanium, was designed using the patient's CT scan and CAD CAM (computer aided design and computer aided manufacturing) technology, meaning it was designed to the patient's exact specifications and measurements.

The implant will provide a new socket for the ball of the femur bone to enter. Behind the implant and between the pelvis, doctors have inserted a graft containing bone stem cells.

The graft acts as a filler for the loss of bone. The patient's own bone marrow cells have been added to the graft to provide a source of bone stem cells to encourage bone regeneration behind and around the implant.

Southampton doctors believe this is a game changer. Douglas Dunlop, Consultant Orthopaedic Surgeon, conducted the operation at Southampton General Hospital. He says: "The benefits to the patient through this pioneering procedure are numerous. The titanium used to make the hip is more durable and has been printed to match the patient's exact measurements this should improve fit and could recue the risk of having to have another surgery.

"The bone graft material that has been used has excellent biocompatibility and strength and will fill the defect behind the bone well, fusing it all together."

Over the past decade Mr Dunlop and Professor Richard Oreffo, at the University of Southampton, have developed a translational research programme to drive bone formation using patient skeletal stem cells in orthopaedics.

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Groundbreaking hip and stem cell surgery in Southampton

The Stem Cell Blog | Adult Stem Cell Patient Empowerment

In STEM CELLS IN THE NEWS on May 8, 2014 at 5:47 pm

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But14 years late to the party. Reminds me of the last scene in Schindlers list. How many lives could have been saved? How much suffering could have been eased. Well, lets do the math.

in 2005 there were 2,448,000 deaths in the u.s. 4 of the top 6 killers were:

Heart disease (652,000 deaths) Cancer (559,000 deaths) Stroke (143,000 deaths) Diabetes (75,000 deaths)

There were a total of 1,429,000 deaths in 2005 from these 4 diseases and there are renowned stem cell treatment centers around the world that have been successfully treating patients with these disease for years. Around the world, people with these disease are actively receiving asc treatments and benefiting from them.

See more here:
The Stem Cell Blog | Adult Stem Cell Patient Empowerment

The Adult Stem Cell Foundation

ADULT STEM CELL THERAPY IS AVAILABLE NOW!

Australia - New Zealand - Asia & Pacific Rim - China - Italy

watch the latest video here

Our Foundation is a philanthropic (not for profit) charitable organization that will advise un-well people how to get access to Adult Stem Cell Therapy (ASCT). The Foundation will also promote a campaign showing how it is possible to prevent or limit the progression of these degenerative diseases to the general public. Degenerative disease is an uncontrolled escalating world problem that if not controlled has the ability to bankrupt our health systems. Very little is being done to control this epidemic in Degenerative Disease.

The purpose of the Foundation is to show that people suffering from a degenerative disease like Parkinsons, Multiple Sclerosis, Diabetes 1 & 2, Stroke, Alzheimers, Spinal Cord injuries, Liver diseases, Myocardial infarction, (to name a few) can now receive Adult Stem Cell Therapy that may change their quality of life for the better. That there is now HOPE.

The Foundation wants to especially help children suffering from any debilitating or degenerative disease, for example like Cerebral Palsy, Muscular Dystrophy, Autism, Spinal injuries, Cystic fibrosis, ADHD to name a few. Stem cell treatments have progressed in leaps and bounds in these areas and we have state of the art clinics that specialize in these types of child diseases. Children, because they are still growing can usually benefit substantially from an early intervention using stem cell therapies. Just fill out the Application Formfor a experimental transplant and we will be only to happy to advise both the parents or a fund raising group seeking to help a particular child.

The Adult Stem Cell Foundation has also become the Information Centre in Australasia for clinics that have demonstrated they abide by the highest medical standards, and have a proven track record with these therapies.

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The Adult Stem Cell Foundation

Ground breaking hip and stem cell surgery completed using 3D-printed implant

Doctors and scientists in Southampton have completed their first hip surgery with a 3D printed implant and bone stem cell graft.

The 3D printed hip, made from titanium, was designed using the patient's CT scan and CAD CAM (computer aided design and computer aided manufacturing) technology, meaning it was designed to the patient's exact specifications and measurements.

The implant will provide a new socket for the ball of the femur bone to enter. Behind the implant and between the pelvis, doctors have inserted a graft containing bone stem cells.

The graft acts as a filler for the loss of bone. The patient's own bone marrow cells have been added to the graft to provide a source of bone stem cells to encourage bone regeneration behind and around the implant.

Southampton doctors believe this is a game changer. Douglas Dunlop, Consultant Orthopaedic Surgeon, conducted the operation at Southampton General Hospital. He says: "The benefits to the patient through this pioneering procedure are numerous. The titanium used to make the hip is more durable and has been printed to match the patient's exact measurements -- this should improve fit and could recue the risk of having to have another surgery.

"The bone graft material that has been used has excellent biocompatibility and strength and will fill the defect behind the bone well, fusing it all together."

Over the past decade Mr Dunlop and Professor Richard Oreffo, at the University of Southampton, have developed a translational research programme to drive bone formation using patient skeletal stem cells in orthopaedics.

The graft used in this operation is made up of a bone scaffold that allows blood to flow through it. Stem cells from the bone marrow will attach to the material and grow new bone. This will support the 3D printed hip implant.

Professor Oreffo comments: "The 3D printing of the implant in titanium, from CT scans of the patient and stem cell graft is cutting edge and offers the possibility of improved outcomes for patients.

"Fractures and bone loss due to trauma or disease are a significant clinical and socioeconomic problem. Growing bone at the point of injury alongside a hip implant that has been designed to the exact fit of the patient is exciting and offers real opportunities for improved recovery and quality of life."

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Ground breaking hip and stem cell surgery completed using 3D-printed implant

Chances of stem cell hip surgery 'very slim'

Chances of stem cell hip surgery 'very slim'

6:00am Saturday 17th May 2014 in News By Melanie Adams, Health Reporter

IT IS a revolutionary new operation that uses a 3D hip printed from a machine.

But the chances of you having hip surgery using the state-of-the-art implant and stem cells is very slim - according to a Southampton expert.

Only a minority of hip replacement patients will have access to the sophisticated technique that was pioneered at Southampton General Hospital this week.

It is the first time that doctors and scientists in the city have done hip surgery using a 3D printed implant in combination with bone stem cells graft.

It is hoped that the new titanium hip, which was designed using the patient's CT scan and state-of-the-art technology, will last longer because it has been made to fit the patient's exact measurements.

Meryl Richards, from Hampshire, who has had hip troubles since she was involved in a traffic accident in the 1970's, was the patient to receive this revolutionary hip.

Vitali Goriainov, a clinical registrar working at the University of Southampton, told the Daily Echo that the operation offers an alternative for the most complicated of hip patients, like Mrs Richards who has had several operations on her hip but still suffered excruciating pain.

For these patients the surgery, which was conducted by Douglas Dunlop, Consultant Orthopaedic Surgeon, is now available and the hospital already has two more patients lined up for the operation.

Read the original post:
Chances of stem cell hip surgery 'very slim'

Ground breaking hip and stem cell surgery completed using 3D printed implant

Doctors and scientists in Southampton have completed their first hip surgery with a 3D printed implant and bone stem cell graft.

The 3D printed hip, made from titanium, was designed using the patient's CT scan and CAD CAM (computer aided design and computer aided manufacturing) technology, meaning it was designed to the patient's exact specifications and measurements.

The implant will provide a new socket for the ball of the femur bone to enter. Behind the implant and between the pelvis, doctors have inserted a graft containing bone stem cells.

The graft acts as a filler for the loss of bone. The patient's own bone marrow cells have been added to the graft to provide a source of bone stem cells to encourage bone regeneration behind and around the implant.

Southampton doctors believe this is a game changer. Douglas Dunlop, Consultant Orthopaedic Surgeon, conducted the operation at Southampton General Hospital. He says: "The benefits to the patient through this pioneering procedure are numerous. The titanium used to make the hip is more durable and has been printed to match the patient's exact measurements -- this should improve fit and could recue the risk of having to have another surgery.

"The bone graft material that has been used has excellent biocompatibility and strength and will fill the defect behind the bone well, fusing it all together."

Over the past decade Mr Dunlop and Professor Richard Oreffo, at the University of Southampton, have developed a translational research programme to drive bone formation using patient skeletal stem cells in orthopaedics.

The graft used in this operation is made up of a bone scaffold that allows blood to flow through it. Stem cells from the bone marrow will attach to the material and grow new bone. This will support the 3D printed hip implant.

Professor Oreffo comments: "The 3D printing of the implant in titanium, from CT scans of the patient and stem cell graft is cutting edge and offers the possibility of improved outcomes for patients.

"Fractures and bone loss due to trauma or disease are a significant clinical and socioeconomic problem. Growing bone at the point of injury alongside a hip implant that has been designed to the exact fit of the patient is exciting and offers real opportunities for improved recovery and quality of life."

Excerpt from:
Ground breaking hip and stem cell surgery completed using 3D printed implant

Ground breaking hip and stem cell surgery in Southampton

PUBLIC RELEASE DATE:

16-May-2014

Contact: Becky Attwood r.attwood@soton.ac.uk 44-023-805-92116 University of Southampton

Doctors and scientists in Southampton have completed their first hip surgery with a 3D printed implant and bone stem cell graft.

The 3D printed hip, made from titanium, was designed using the patient's CT scan and CAD CAM (computer aided design and computer aided manufacturing) technology, meaning it was designed to the patient's exact specifications and measurements.

The implant will provide a new socket for the ball of the femur bone to enter. Behind the implant and between the pelvis, doctors have inserted a graft containing bone stem cells.

The graft acts as a filler for the loss of bone. The patient's own bone marrow cells have been added to the graft to provide a source of bone stem cells to encourage bone regeneration behind and around the implant.

Southampton doctors believe this is a game changer. Douglas Dunlop, Consultant Orthopaedic Surgeon, conducted the operation at Southampton General Hospital. He says: "The benefits to the patient through this pioneering procedure are numerous. The titanium used to make the hip is more durable and has been printed to match the patient's exact measurements this should improve fit and could recue the risk of having to have another surgery.

"The bone graft material that has been used has excellent biocompatibility and strength and will fill the defect behind the bone well, fusing it all together."

Over the past decade Mr Dunlop and Professor Richard Oreffo, at the University of Southampton, have developed a translational research programme to drive bone formation using patient skeletal stem cells in orthopaedics.

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Ground breaking hip and stem cell surgery in Southampton

Stem Cells to The Rescue: Repairing The Hearts

FRESNO, Calif. (KFSN) --

"Grace is what's carried me through this," Minch told Ivanhoe.

Ten years ago, at just 49, the choir singer and her husband were told she would need a quadruple bypass.

"Now we are at the point where my heart is severely damaged and nothing is really helping," Minch said.

Doctors said a heart transplant was her only option, but she'll soon find out if she'll be accepted into a new trial that could use her own stem cells to help repair the once thought irreversible damage, "or even create new blood vessels within areas of the heart that have been damaged," Jon George, MD, Interventional Cardiologist, Temple University School of Medicine, told Ivanhoe.

First, stem cells are taken from a patient's bone marrow. Then using a special catheter and 3D mapping tool, the cells are injected directly into the damaged tissue.

"We have results from animal data that show blood vessels regrow in the patients that actually get stem cell therapy," Dr. George said.

It's a possible answer to Debbie's prayers.

Temple University Hospital is currently pre-screening patients for the trial. For more information, call 215-707-5340.

------

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Stem Cells to The Rescue: Repairing The Hearts

Langford's Hannah Day doing well in struggle with cancer

Langfords Hannah Day is all thumbs up after finding out her blood is currently cancer free, half way through her stem cell transplant process. Hannahs mother says the four-year-old is thriving.

image credit: Submitted photo

Langford resident Hannah Day has passed a milestone in her struggle against leukemia, her second cancer diagnoses in her short life.

Mother Brooke Ervin said four-year-old Hannah, who underwent a stem cell transplant with her mother as host, has had a recent biopsy come back revealing there are currently no traces of the cancer in her blood.

My stem cells are doing the job that (doctors) hoped that they would, Ervin said. Shes thriving. The doctors cant believe it. They just went in there and theyre chasing her around and joking with her and tickling her.

Hannah has been discharged from B.C. Childrens Hospital, though still has to attend clinic up to four times per week, keeping her family in Vancouver.

Thats the hugest and best news we could ever ask for, Ervin said of the discharge.

At the time of writing Day was on Day 54 since the transplant, with Day 100 being the big goal to get to. The process is causing Hannah to break out in burns, as the stem cells attack her body and burn her from the inside, Ervin said. This is an expected side effect, she added.

Despite the good news, Ervin is still being told there is a 60 per cent chance of a relapse, and if that happens there are no other treatment options, as the transplant has been Hannahs last hope for health.

The mood is high for all, even if the family isnt in the clear quite yet.

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Langford's Hannah Day doing well in struggle with cancer

#Shake4Mike: 'I wanted to be his rock in return'

He was still waiting to hear back from a job interview, so I assumed it was about that and I got really excited, she says. I tried to ring a few times, and eventually I got through over quite a patchy line. He said, 'I think Ive got leukaemia. When you hear those words, you know how serious it is. I just told him, 'Im going to get home as quickly as I can.

The news that followed was devastating. Mike, 29, was diagnosed with acute lymphoblastic leukaemia and is currently undergoing intense chemotherapy six times a week at Bristol Royal Infirmary. Such is the severity of his condition that doctors have said he needs a stem-cell transplant to save his life and time is running out.

As has been widely reported this week, his family, who live in Somerset, have only until the start of July, when his chemotherapy course ends, to find a suitable donor. Normally a third of people requiring the operation are able to find a sibling match. All of his three brothers have already been tested, but none has been successful.

He and his loved ones are now searching the Anthony Nolan stemcell donor register for a match with a stranger willing to help. The charity warns, however, that it can normally find a suitable donor for only around half the people who need a life-saving stem-cell transplant.

Kate, as a result, has taken matters into her own hands. This week, she launched a public campaign for people to sign up to the register, urging social media users to post silly videos of themselves shaking their faces from side to side something the couple used to film each other doing to promote the campaign she has called #Shake4Mike.

Her hope, of course, is that more signatories to the register will boost her fiancs chances of finding a donor and she has been inundated with responses. Some have been so funny theyve made me laugh out loud.

Indeed, in conversation, the Nottingham University graduate is strikingly upbeat and resilient. But optimism in the face of tragedy is a skill she has already been forced to master. In 2005, her 59-year-old father, David, died suddenly at the family home in Aylesbury, Buckinghamshire, after developing a blood clot following an operation on a hip he had broken skiing. He had just eaten his Sunday roast and walked on his crutches to the living room and died.

A few weeks later, her grandparents followed him. In 2008 her mother, Ali, invited her best friend, Simon Blackett, to move in to help support the family. Within two months, the 38-year-old suffered a fatal brain haemorrhage.

It was a year after this latest loss that the couple first met. Kate says her fianc has helped turn her life around and that, ever since she received that phone call in Burma, she has been determined to be his rock in return.

Still, the journey home was in itself enough to test her emotional strength. She remembers a horrendous 48-hour blur of buses and planes. Mum picked me up straight from Heathrow and drove me to the hospital. I thought when I saw her Id break down, but shes really strong and that helped so much. When I got to the hospital and saw him he looked pale, but other than that it was just a relief to be with him, says Kate.

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#Shake4Mike: 'I wanted to be his rock in return'