UAE stem cell therapy for coronavirus treats over 2000 patients, 1200 fully recover – MENAFN.COM

(MENAFN - Khaleej Times) The Abu Dhabi Stem Cell Centre (ADSCC) has now treated more than 2,000 patients suffering from Covid-19, with 1,200 already fully recovered from the effects of the virus.

ADSCC announced today that it had succeeded in ramping up the number of treatments from 73 in the initial clinical trial .

The large increase was as a result of a major effort by staff at the centre to treat as many people as possible following the UAE Government''s decision to make it available free of charge to all moderate-to-high risk Covid-19 patients in the country.

Also read: UAE expects Covid-19 vaccine by end of 2020 or early 2021

The Government''s decision came after the treatment, branded UAECell19, demonstrated efficacy and an impressive safety profile reflected in the absence of significant changes in adverse events reported, an absence of any unexpected serious reactions (such as anaphylaxis, allergic reactions or sudden death) and an absence of any lung complications as determined by radiological exams from inhalation of the nebulized product.

A team of doctors and researchers at ADSCC, led by Dr Yendry Ventura, announced in May that they had developed a new treatment for Covid-19 patients. UAECell19, an autologous stem cells based therapy, appears to help the body fight the virus and makes the disease less harmful.

Following an initial trial, researchers were able to conclude that UAECell19 reduced the duration of hospitalisation from 22 days to just six, when compared to patients who had received standard treatment.

Further analyses revealed that patients treated with the stem cells were 3.1 times more likely to recover in less than seven days than those treated with standard therapy, and 67 per cent of the patients who received the stem cells treatment owed this recovery to the new treatment.

ADSCC has since secured intellectual property rights protection for UAECell19, which opens the way for the treatment to be shared widely so more patients can benefit.

ADSCC said researchers are at various stages of several investigatory efforts to establish effectiveness (Phase 3 trial), optimal efficacy of dosage, and efficacy to treat other respiratory diseases such asthma, COPD, and cystic fibrosis.

MENAFN2606202000490000ID1100388978

The rest is here:
UAE stem cell therapy for coronavirus treats over 2000 patients, 1200 fully recover - MENAFN.COM

Mini-Organ Research Reveals What COVID-19 Does to the Body – Futurism

In order to understand how COVID-19 spreads throughout the body, ravaging it in myriad ways, doctors are growing miniature balls or organ-like tissue called organoids, and infecting them again and again.

The results, Nature News reports, are particularly troubling: the miniature lungs, livers, kidneys, hearts, intestines all showed signs of damage. The series of studies reveals with shocking clarity that COVID-19 can cause far more than a lung infection.

Of course, thats not exactly news. This harrowing list of survivors and medical workers horror stories gathered by SFGate includes heart attacks, strokes, long-term lung damage, incontinence, skin damage, and other serious complications for supposed mild cases of the coronavirus:

Thats just one of the many, many stories they gathered about the ways a road to recovery from COVID-19 is neither linear nor something that shouldnt be feared.

That said, for all their benefits, organoids are still imperfect. Per Nature, theyre far more simplistic than a full-sized organ. And because theyre not all connected in the same body, doctors can only use them to study the impacts on a single organ in isolation.

We know the cells die but we dont know how, Weill Cornell Medicine stem cell biologist Shuibing Chen told Nature of her study on miniature lungs.

Even though questions remain, its clear those impacts are serious. Various studies found that the coronavirus caused serious damage in several organs, and may lead to indirect damage in others. It also became clear that the coronavirus can infect and spread through blood vessels, leading to a more serious, widespread case.

To figure that out, biologists will need to develop more sophisticated and realistic organoids and try their experiments again, Nature reports.

It is too early to say how relevant they are, Bart Haagmans, an Erasmus MC virologist who ran a study on gut organoids, told Nature.

See the original post:
Mini-Organ Research Reveals What COVID-19 Does to the Body - Futurism

My Friend Was Struck by ALS. Heres How Hes Fighting Back – WIRED

Brian Wallach's left hand cramped and he dropped his pen. Ten minutes later, it happened again. Annoying. He'd spent months preparing for this case. He'd joined the US Attorney's Office, a dream job, almost three years earlier. He was in the midst of prosecuting the surviving member of a group that had smuggled guns into Chicago from Indiana. The trial was a few weeks away. And now these cramps. He chalked it up to stress and moved on.

That was April 2017. On July 31, Brian and his wife, Sandra Abrevaya, had their second daughter, jaundiced but otherwise healthy, so all three stayed in the hospital a week. That's when Brian started coughing, barking, unable to finish a sentence. Sandra told him to see a doctor, so he did. He ticked off every symptom he could think of: the cough, the cramp, and also a muscle twitch in his left arm.

That physician sent Brian to a neurologist the next day. The neurologist talked through Brian's symptoms, looked at his tongueit was subtly undulating, something Brian hadn't noticed. The doctor then told him the news: He likely had amyotrophic lateral sclerosis. ALS. Lou Gehrig's disease. If he was right, the doctor said, Brian had approximately six months to live.

That was the same day Sandra and their daughter had come home from the hospital. Brian barely knew what ALS was. It seemed impossible that it would have found him, much less imposed so strict a deadline.

Brian's first call on the drive home was not to Sandra but to Nick Morris, a neurologist at the University of Maryland and a friend from college. Before he could tell Sandra the news, he needed someone to help him process it. Nick obliged, explaining that there's no one definitive test for ALSin fact, a conclusive diagnosis often requires a monthslong process of elimination.

Sandra called in the middle of that conversation, and Brian switched over. She caught something in his voice. No, everything wasn't OK, he told her. No, he couldn't say it over the phone. Yes, he was on his way home.

Sandra paced while the girls napped. When he arrived she ran out to the car and jumped into the passenger seat. Nick was still on speakerphone. I need you to get off the phone because I don't know what's going on, Sandra said to them both. And then Brian told her.

That's not that bad, right?

No, Brian replied. It is.

I'll spare you some suspense. The neurologist was right about ALS, albeit for incomplete reasons, but he was wrong about the timetable. Three years later Brian is still alive.

ALS is a cruel disease. Motor neurons in the brain and spinal cord gradually degrade and then die, robbing the sufferer of control over their muscles. Eventually patients cannot move or speak or eat or breathe. There is no cure and, except in a minority of inherited cases, no known cause. Once symptoms appearin an arm or a leg or a handthe typical survival rate is three to five years. It is fatal in virtually all cases.

Brian was one of roughly 5,000 people in the US to receive an ALS diagnosis in 2017. He's one of more than 16,000 patients living with the disease in the country today. Each has faced some version of Brian's moment in the car: mortality in sharp relief. A loved one at home who doesn't yet know. A decision about how to spend whatever time they have left.

Brian and I have known each other for three decades. Our lives have played out as variations on the same theme: good schools, bad work-life balance, two kids, settled down hundreds of miles from where we grew up. He and Sandra told me this story when I visited them last spring. We were sitting in a bedroom addition of their suburban Chicago home, built with a ramp for the inevitable day that Brian's disease will confine him to a wheelchair.

View post:
My Friend Was Struck by ALS. Heres How Hes Fighting Back - WIRED

Who is Nick Cordero and how is he doing after his coronavirus battle? – The Sun

BROADWAY star Nick Cordero contracted coronavirus on March 20 of this year according to his wife Amanda Kloots.

The Tony Award-nominated actorfor Bullets over Broadway has been in the ICU since late March, with his other half keeping fans updated on his progress.

5

Earlier this year in May, Amanda tearfully revealed that Nick's condition was "going a little downhill."

Nick Cordero is a Canadian Broadway actor.

The 41-year-old has performed in the likes of A Bronx Tale The Musical, Waitress, and Rock of Ages.

He has collected several accolades for his theatre work over the years from the Outer Critics Circle and the Theatre World Awards.

Nick caught coronavirus earlier in March this year and has faced a series of ups and downs since he contracted the virus.

He was hospitalized in ICU after doctors first misdiagnosed him with pneumonia.

Nick has suffered a variety of complications as a result of COVID-19.

Doctors were not only forced to amputate his right leg because of blood clots, but the Broadway star has also had to undergo stem cell treatment to strengthen his lungs.

Nick's wife Amanda, who is single-handedly raising their one-year-old son Elvis while Nick is ill, regularly takes to Instagram to update fans on his condition.

5

In May, Amanda tearfully shared that Nick's condition was worsening.

"Nick has had a bad morning. Unfortunately, things are going a little downhill at the moment," she shared.

She added "I know that this virus is not going to get him down.

"This is not how his story ends. So just keep us in your thoughts and prayers, thank you."

A week beforehand, she announced that Nick was finally conscious after a month-long coma.

"This infection that is leftover from when he went into septic shock the last time is still in his lungs and just kind of sitting there. They are doing everything they can to clean it out every day but its just not getting better.

5

The mom-of-one also told fans doctors could "lower his vent settings" once the infection goes away.

That will begin the process of trying to get him breathing on his own.

She added: They are cleaning him out every day and hes on antibiotics, so it can happen and its gonna happen because like Ive said from the beginning, the doctor told me from the beginning, if we have a positive attitude, there are options.

"This infection is gonna go away and he is gonna get off that ventilator. And thats the only mindset that I have right now.

Nick is fighting for his life every day in that ICU and I know he isnt giving up. Were not giving up. Nobody is giving up.

Amanda, 38, recently updated fans that husband Nickhad a "great day" after visiting the actor at Cedars-Sinai hospital in LA on Sunday.

She told her Instagram followers: "He was having such a great day.

"He was more alert than I've seen him in a while and he was really following [with] his eyes a lot."

5

Amanda also revealed the sweet "little tradition" she has during her hospital visits to see Nick - playing and singing along to seventies track Our House by Crosby, Stills, Nash & Young.

She added: "I say a big prayer, hold his hand and give him a kiss and tell him we will live together in our house one day and keep fighting and it's going to happen."

5

Nick has spent a total of 82 days in ICU since he was infected with the coronavirus.

Nick's good day comes as a morale boost after Amanda revealed that a CT scan on his lungs confirmed that he would not survive a lung transplant.

Exclusive

Exclusive

"You feel like sometimes there's lots of hope and then sometimes there's not as much hope. We're basically trying to see if we can get him stable and strong enough to have more options," she said.

"It's monotonous and hard on a daily basis - very, very hard."

Read the original here:
Who is Nick Cordero and how is he doing after his coronavirus battle? - The Sun

Family of 18-year-old Doncaster boy who died of cancer raise thousands for charities that helped him – Doncaster Free Press

Joel Esan, 18, from Bessacarr, Doncaster sadly passed away on June 14, 2020 after he had been fighting a rare type of leukaemia, known as Acute Leukaemia of Ambiguous Lineage for the last two years.

Despite multiple rounds of chemotherapy, radiotherapy and a stem cell transplant from his mother, Joels aggressive form of cancer returned twice since he was first diagnosed at 16-years-old in 2018.

In April earlier this year, doctors told Joel that he only had three months to live because the leukaemia had returned and the disease had mutated meaning no further treatment could cure him.

Joel's final wish was for his family to raise money for the organisations that cared for him.

The 18-year-olds final wish was for his family to raise money for the charities that helped care for him, in particular The Teenage Cancer Trust, Clic Sargent, Laurens Legacy, Starlight and Anthony Nolan.

Joels relatives have fundraised 5,251 in just two days through their dedicated donation page to ensure other families and people like Joel can access help and support when they most need it.

His brother, Patrice Esan explained how it feels to have raised more than half of their 10,000 target.

"It just makes us so happy because we know Joel would have wanted us to raise this for those charities, Patrice said.

Joel pictured next to his sister, Charlotte, sister-in-law Zoe and brothers Patrice, Lee and Lewis.

"He would be happy looking down on us knowing we are doing a good job for him to continue his legacy and to help other people.

Joels family have expressed their thanks for the Haematology ward at The Royal Hallamshire Hospital in Sheffield who helped care for him and made the entire experience a touch less difficult to bear.

The 18-year-old spent his last moments surrounded by his loved ones in his family home.

Patrice added: He fought so hard and everything he did, he never complained about a single thing which was obviously a credit to him.

Joel (right) next to his brother Patrice (centre) and dad Femi (left).

"Even in his last moments he spoke to us and asked us to get out of bed and in those moments, he stood up in mine and my sister's arms and passed away in our arms.

"He kind of used his last strength to get up which was quite a sudden thing to happen and it was nice as a family to be together and to use his last strength to be with us.

"He was the best brother you could ask for.

Joels relatives are now urging people from Black, Asian and minority ethnic backgrounds (BAME) to register to donate their stem cells with Anthony Nolan, a charity which has a register for those who are willing to donate their stem cells to help people with blood cancers.

Its after Joel was unable to find a 100% match for his transplant and instead received cells from his Mum who was only a 50% match, which made it less effective.

White Europeans have almost 70% chance of finding a stem cell donor, while BAME people have less than 20% of finding a successful match according to Anthony Nolan.

Original post:
Family of 18-year-old Doncaster boy who died of cancer raise thousands for charities that helped him - Doncaster Free Press

Michael Schumacher: Everything There Is to Know About His Health, Condition, and Accident – Essentially Sports

Fate can be cruel at times. Even if youre on top of the world, having achieved everything, fate can snatch it all away in an instant. Michael Schumacher retired from F1 for the second time in 2012 but he didnt get very long to enjoy his time off from the racetrack. Heres everything we know about the F1 legend today and what happened on the fateful day of his skiing accident.

Before diving into the details, be warned that a lot of this information is mere speculation. The Schumacher family has rightfully kept the German drivers health condition under wraps. Therefore, take this information with a pinch of salt.

On December 29, 2013, mere days away from his 44th birthday, Michael Schumacher suffered a near-fatal accident whilst skiing in the French Alps. The 7 times World Champions head hit a rock while crossing an unpatrolled skiing area. Thankfully, he survived because of his ski helmet. However, his injuries were severe.

Brain injury resulted in Schumacher being placed in a medically induced coma. Michael regained consciousness only in June 2014. Following this, Schumacher left the hospital to recover and rehabilitate from his home in Switzerland.

There have been several conflicting reports regarding Schumachers condition and proceeding sequence of events. Some reports claim the 7 times World Champion is paralyzed and confined to a wheelchair. Moreover, some sources suggest Schumacher has difficulty speaking and is suffering from memory loss.

His family hasnt gone on record to speak about the F1 legends health. However, his manager revealed that Michael was slowly progressing and making small steps towards recovery.

Recently, many reports surfaced, claiming Schumacher was to undergo surgery. Allegedly, doctors planned on performing a stem cell surgery to regenerate Michaels nervous system.

The Schumacher family denied these reports, claiming they wouldnt opt for surgery, given the present condition. However, its still unclear if Schumacher does undergo surgery if and when the Coronavirus situation improves.

Michael Schumacher almost seemed immortal during his period of F1 domination. Schumacher always believed in never giving up and we can only hope The Michael conquers his injuries as soon as possible.

More:
Michael Schumacher: Everything There Is to Know About His Health, Condition, and Accident - Essentially Sports

Anonymous US stem cell donor saves the life of Norwich girl – Eastern Daily Press

PUBLISHED: 18:00 18 June 2020

Simon Parkin

Imogen Roe returned home to Norfolk after 100 days in isolation in hospital. Picture: Anna Dagless

Archant

Email this article to a friend

To send a link to this page you must be logged in.

Imogen Roe, from Norwich, had just turned six when she was treated for routine tonsillitis. But her worried parents, Anna and Dean, took her back to the doctors when they noticed abnormal bruising and a rash on her body.

They were told to take Imogen to their local hospital, and were soon confronted with the devastating diagnosis.

Mum Anna, 38, said: We suspected it was a reaction to penicillin at worst. But within an hour of being at our local hospital we were told it was leukaemia, and within 24 hours we were in Addenbrookes Hospital. It all happened so fast, I dont remember feeling much other than panic and shock.

Because of the aggressiveness of her leukaemia, young Imogen began two-and-a-half years of high dosage chemotherapy.

Anna said: Imogen was such a trouper, and very co-operative which made for a very easy patient!

I cannot believe how well she just got on with things; cannulas, nose tubes, general anaesthetics, surgery - even though at times she has been very scared about procedures.

During this time the family was divided, with Imogen and her mum in Addenbrookes, whilst Dad Dean, 39, stayed at home with their other two children, Imogens twin sister Charlotte, and older brother Liam, 11.

MORE: Esm, three, wins 19-month cancer battle but cannot celebrate traditional bell ringing

In January 2019, almost three years after her diagnosis, young Imogen finished her chemo and rang her end of treatment bell to huge applause from doctors, nurses, hospital staff - and her proud, but exhausted parents.

The young family were finally able to get their lives back on track, but unfortunately more heartbreaking news was just around the corner.

Anna said: It was July 2019, almost three years to the day since Imogens original diagnosis, and we had just bought a puppy and booked a family holiday abroad with friends. Then we noticed that familiar rash on her legs, and were told to bring her to hospital.

After undergoing tests, doctors confirmed the worst Imogen had relapsed and the leukaemia had come back.

Doctors revealed that, in addition to further chemotherapy, Imogens best chance of beating the disease was to have a blood stem cell transplant from a matching donor.

Imogens siblings were both tested, and the family were delighted to be told that her sister Charlotte was a 100% match.

However, after further tests, they were confronted with shocking news after a decade of thinking Charlotte and Imogen were non-identical twins, they were in fact identical, which meant that Charlotte would not be a suitable donor after all.

Doctors began looking for Imogens potential lifesaver elsewhere searching the worldwide register of potential blood stem cell donors, hoping to find a perfect stranger who happens to be Imogens genetic twin.

With Imogens life hanging in the balance a match was found. Cord blood, donated by a new mother in the USA and frozen nine years prior, was a perfect match for Imogen. This was the only suitable match for Imogen anywhere in the world.

MORE: How support, prayers and herbal rememdies helped nurse beat coronavirus

As the frozen cord blood was prepared to be flown from America to the UK, Imogen had 10 days of conditioning treatment prior to transplant; four days of extremely strong chemotherapy, and then eight sessions of total body irradiation, to prepare her to receive the new blood stem cells.

This is an incredibly vulnerable point in any treatment plan. The new marrow should, over a few weeks, start to regenerate within the body, but for Imogen, after 36 days of daily blood tests, there was still no sign of any new cells being manufactured.

Her mum said: It was a very serious situation as without any white cells to fight off infection, Imogen was extremely vulnerable even from her isolation room, as you can pick up bugs from your own body.

Ten days post transplant she got an infection, and she went into septic shock. This led to several serious viruses, a chest infection, and bacterial infection. We had the rapid response team on standby for a transfer to intensive care, but Imogen pulled through, just as her dad arrived after making the five hour journey from our home.

Imogen remained in isolation in Bristol for 99 days, fighting off multiple infections, whilst dad Dean travelled the five hours back and forth between home and the hospital to bring Anna clean clothes and supplies.

Finally, Imogen was transferred back to Addenbrookes to continue her recovery one step closer to home.

MORE: Wife of rugby star launches new business two years after being given a month to live

On March 13, in the midst of the Covid-19 pandemic, she was finally discharged and returned home to her mum, dad and siblings, who are now all self isolating.

It had been 170 days since she, or mum Anna, had seen any extended family.

Speaking about Imogens anonymous donor, Anna said the family were acutely aware of the luck involved in finding a match.

She said: Imogen had just one match. There are some people we know through our time in hospitals who were fortunate enough to have a selection of matches, and many others are still waiting for a match that may never come.

If you are aged between 17 and 55 and in general good health, you take the first step to register as a blood stem cell donor by registering for a home swab kit at dkms.org.uk

If you value what this story gives you, please consider supporting the Eastern Daily Press. Click the link in the yellow box below for details.

See the article here:
Anonymous US stem cell donor saves the life of Norwich girl - Eastern Daily Press

British boy who came to Singapore for treatment for aggressive cancer is ‘almost ready to go home’ – CNA

SINGAPORE: About nine months ago, doctors in the UK told Oscar Saxelby-Lees parents there was nothing more they could do for him all treatment options had been exhausted and there was only palliative care left for the little boy.

But after coming to Singapore for anexperimental treatment for acute lymphoblastic leukaemia, Oscar is now almost ready to go home after receiving news on Monday (Jun 15) he has been free of cancer for almost six months.

Since he was diagnosed in December 2018, he hasundergone rounds of chemotherapy, months in isolation, several stem cell transplants and a treatment in Singapore that only one other child in the world has received.

The six-year-old is set to undergo a check up later this week, and will hope to be given the all clear to fly home, his mother Olivia told CNA.

Hes like our little miracle. Its incredible, I couldnt express to you the feelings were feeling now, she said.

As long as all is okay and nothing needs to happen, or nothing needs to be changed, then we should be ready to go (home), which is incredible and for Oscar, is everything.

Hes a little boy who wants to experience life and to most of all, be with his family. He is really excited about it."

Going home will bringits own difficulties.

It is a huge step to go back. Singapore is our security net, and thats why its so hard for us as parents to kind of pack up and go and leave, Olivia explained.

I say a security net for us because when we go home, if anything were to happen to Oscar we are kind of worried because if anything did happen, where would you go?

But to just see our family again we are desperate just to get home to see people, just to see them.

"I know at the moment it is difficult, but just to have a cuddle, or you know, some support in front of us rather than over the phone or virtually its a real hard situation to be in.

COMPASSIONATE TREATMENT WAS LAST HOPE

The treatment atNUH was Oscars last hope. In the UK, doctors had battled for months to rid his body of the cancer.

But despite a stem cell transplant and four rounds of chemotherapy that left him very weak, the leukaemia kept coming back.Doctors told his parents there was no other treatment, and that the cancer would take his life.

The little boy from Worcester, England flew to Singapore after the family crowdfunded 500,000 (S$885,000) for a new form of treatment, in which immune cells from a patients blood aredrawn and equipped with a Chimeric Antigen Receptor (CAR-T).

The receptor binds itself to a specific protein on the cancer cell and activates the CAR-T cells to kill the cancer cells.

This particular form of CAR-T treatment is different and more difficult because the leukaemia cells resemble Oscars immunity system, Associate Professor Allen Yeoh, head of paediatric oncology at NUH, explained previously.

Oscar started treatment on Christmas Eve last year and three weeks later, was given the best news that there were no detectable cancer cells in his body the first major step. But there were always concerns the cancer could make a comeback, as it did previously.

Diseases like Oscars are really reluctant to give up, theyre quite vile, Olivia said. It gets progressively nasty.

IT HAS BEEN RELENTLESS

Over the last few months, Oscar has battled several conditions as a result of complications and undergone more surgeries and transplants.

He was diagnosed with both Graft versus host disease (GvHD) and Thrombotic microangiopathy(TMA) that caused him shaking spells, pain and weakness.

Brain damage also caused him problems with his mobility, and he uses a frame or needs a hand to walk.

Some of the side effects of the treatment have been relentless, Olivia said, adding that Oscar suffers from sickness, diarrhea, mood swings and mobility issues.

Hes had really bad tremors since he was diagnosed with brain damage post CAR-T (treatment). But he has done amazingly well with it, she said.

Hes had numerous side effects. It goes from something as simple as hair loss to, you know, real damage to the body. Oscar has struggled immensely from his mobility.

He's very frail, his legs are very weak. He is only just managing to walk without a (walking) frame.

Oscar was discharged just days after Singapore implemented a circuit breaker to curb the spread of COVID-19, and he has been battling the tremors while staying in.

Hes walking with a parents hand, or just about, maybe taking a couple of steps. Its like training a toddler again, and its really hard.

He's come so far but yet he's got so much to cope with on top. It's so hard.

But for Oscar, battling to get back on his feet is not new. When he first arrived in Singapore in November last year, he was so weak from the rounds of chemotherapy and months in isolation that bruises developed on his legs when he walked.

He manages to plow through, he's such a trooper. He really is in an inspiration to us.

It is a huge mountain of accomplishment for the six-year-old boy, Olivia said. We continue to remind him everyday of how far hes come, and how far he will go.

Olivia said they are "so grateful"to the medical staff at NUH for saving Oscars life.

The teams have been incredibly strong with us, and theyve supported our every decision, she said. They are just incredible."

She thanked Dr Frances Yeap, a consultant in paediatric oncology at the hospital and Prof Yeoh, who actually made us come here and forget about everybody elses opinion.

The nurses in Ward 8B at the hospital have also been a source of support for them, Olivia said.

They are a great team and the nurses. The consultants and the team have never doubted Oscar. We are so grateful. They have saved Oscars life.

See the article here:
British boy who came to Singapore for treatment for aggressive cancer is 'almost ready to go home' - CNA

Momenta clears a PhII hurdle on nipo but one big rival remains well in the lead in this packed field – Endpoints News

Beijing-based Sinovac has posted a positive preliminary snapshot of human data from the Phase I/II study of their vaccine for coronavirus, showing that the jab was able to safely spur protective antibodies in more than 90% of the volunteers involved.

The biotech reported Saturday that they had recruited 743 patients for the two-step trial, with 143 in Phase I and the rest in Phase II.

The neutralizing antibody seroconversion rate is above 90%, the company states, which concludes the vaccine candidate can induce positive immune response. Thats about all youre getting at this stage of the process, though, with little hard data in their statement to decipher.

Unlock this story instantly and join 83,600+ biopharma pros reading Endpoints daily and it's free.

SUBSCRIBE SIGN IN

The rest is here:
Momenta clears a PhII hurdle on nipo but one big rival remains well in the lead in this packed field - Endpoints News

Leukemia Therapeutic Market to Witness Exponential Rise in Revenue Share During the Forecast Period 2015 to 2021 – The Canton Independent Sentinel

Cancer is a disease of genes caused by uncontrolled growth of cells. These uncontrolled cells further migrate from the original site to other site through blood and lymph system. There are various type of cancer such as adrenal cancer, leukemia, bone cancer, blood cancer and others. Leukemia is a type of cancer which is formed in blood tissues. Leukemia occurs in bone marrow which is a soft tissue. Leukemia develops by the uncontrolled growth of blood cells in the bone marrow. Leukemia is also defined as a cancer of white blood cells. White blood cells prevent from various infections. Leukemia may be acute or chronic and it also affects red blood cells and platelets.

Some of the common symptoms of leukemia include fever, night sweats, weight loss, enlarged liver, frequent infections and swollen lymph nodes. Acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia and chronic lymphocytic leukemia are some of the different types of leukemia. Acute myeloid leukemia is most prominent in adult people and it is also known as acute myelogenous leukemia. Chronic myeloid leukemia is also known as chronic myelogenous leukemia. Leukemia therapeutics consists of three steps including induction therapy, consolidation therapy and maintenance therapy. Leukemia therapeutic includes chemotherapy, radiation and stem cell transplantation. Leukemia is diagnosed through physical test, blood test and biopsy. Leukemia is also diagnosed by cytogenetics, spinal tap and chest-X ray as suggested by the doctors.

For detailed insights on enhancing your product footprint, request for a Sample here @https://www.persistencemarketresearch.com/samples/3848

North America followed by Europe dominates the global leukemia therapeutics market due to rising incidence of cancer and growing aging population. Asia is expected to show high growth rate due to rising incidence of cancer. China and India are expected to be the fastest growing leukemia markets in Asia region. Some of the key driving forces for the leukemia therapeutic market in emerging countries are increasing R&D investment, large pool of patients and rising government funding.

In recent time there is increased use of leukemia therapeutic due to rising number of cancer diseases across the world. Rising aging population, lifestyle factors and increasing awareness for healthcare are some of the key driving factors for the growth of the global leukemia therapeutics market. In addition, innovative and targeted drug delivery is also fuelling the growth of the global leukemia therapeutics market. However, availability of large numbers of generic form of drugs and limited treatment options are some of the major factors restraining the growth of the global leukemia therapeutics market. In addition, high unmet need for diagnosis is also restraining the growth of the global leukemia therapeutics market.

To receive extensive list of important regions, ask for TOC here @https://www.persistencemarketresearch.com/toc/3848

Off label prescribing would support the growth of the global leukemia therapeutics market. In addition, limited number of market players would supports the entry of new market players. Innovative and safer therapies could develop an opportunity for growth of the global leukemia therapeutic market.

However, adverse effect caused by chemotherapy and radiation therapy could lead a challenge for the global leukemia therapeutics market. Some of the major companies operating in the global leukemia therapeutic market are

Read the rest here:
Leukemia Therapeutic Market to Witness Exponential Rise in Revenue Share During the Forecast Period 2015 to 2021 - The Canton Independent Sentinel