Category Archives: Stem Cell Doctors


Out of this world: Zionsville doctor sends osteoblast cells into space to study drug effects – Current in Carmel

Dr. Melissa Kacena and her team are continuing with the second phase of a two-part bone-healing study which involves mice and space.

Kacena and a team from the Indiana University School of Medicine planned two phases for a project. The first was to study femur fractures in 40 mice to learn the effects of bone-healing when introduced to weightlessness. The second examined results of two drugs when introduced to osteoblast cells in space.

Dr. Melissa Kacena is researching how osteoblast cells react to certain drugs while in space. (Photo illustration)

The first phase was completed in 2017. The second is ongoing.

Cells were launched on a SpaceX CRS-18 launch July 25 at Cape Canaveral, so that Kacena and other scientists could study the effects of a drug called bone morphogenetic protein-2, or BMP-2, which is commonly used to facilitate bone-healing in patients, and another called thrombopoietin, or TPO, most often used to increase platelets in blood that Kacena discovered can also be used to heal bone.

Dr. Tien-Min Gabriel Chu of the IU School of Dentistry co-invented the utility patent for the use of thrombopoietic agents for bone healing.

The osteoblast cells returned from space last month. An analysis should be complete by the end of the year.

Initially, the mice study was supposed to be conducted after the cell study, but because of problems with the cell spaceflight hardware that killed the cells, the order switched.We leap-frogged the order and did the bone-healing study first. We are still processing those tissues from the mice, and we are getting amazing data. Its very interesting, said Kacena, a Zionsville resident. Some data was recently published in scientific reports. We are finding some very interesting things that are not yet published. We are seeing what we hypothesized.

BMP-2, which orthopedic surgeons use for bone-healing, works through mechanical loading, so weight-bearing patients heal efficiently. The drug Kacena is proposing doesnt require loading for the bone to heal properly.

Ours has an advantage up in space flight, or if a patient is bedridden, she said.

The cells in space will be used to examine the effects of BMP-2 and TPO.

One of the reasons we are looking at this is BMP-2 has a risk of developing cancer, a small percentage, Kacena said.

Other side effects of BMP-2 include overgrowth of bone, which can cause spinal fusion.

If we can find something that doesnt have these side effects, this would be a better process, Kacena said.

Because bone cells grow differently in space, Kacena believes cell growth will improve if a patient takes TPO.

We think the cells with the TPO will grow better than the cells with BMP-2, she said

If research proves the hypothesis, TPO could be highly beneficial for astronauts who spend long periods of time in space.

If someone is bedridden or in space flight, they lose 1 to 3 percent of bone mass per month, Kacena said. Osteoporosis causes a loss of 1 percent per year. (Astronauts in space) are usually around 30 to 40 years old and theyre losing more (bone mass) in one month than somebody with osteoporosis loses in a year. Right now, we dont think bone mass stops or plateaus, so they may lose a third of their skeleton (mass), so we knew that testing these drugs on these cells is a good first indication whether it will be helpful in an unloaded environment in space.

The drug could also assist in healing fractures and benefit patients with osteoporosis or military veterans who have been injured while serving.

Thats our overall goal, to improve fracture healing for all patients the soldiers, people with osteoporosis or people in car accidents, Kacena said.

Kacena said the drug patent was approved and the team is moving forward with pre-clinical trials.

Melissa Kacena, center, observes as undergraduate Aamir Tucker, left, and post-doctoral fellow Paul Childress practice a surgical technique that will be used on 40 mice before they are launched into space for the first phase of a two-part project. (File photo by Ann Marie Shambaugh)

Although Dr. Melissa Kacena feels strongly about testing the effects of bone-healing drugs on mice and osteoblast cells in space, she also stresses the importance of STEM, or science, technology, engineering and mathematics, education for students. She invited eight Indiana University students to attend the space launch for the second phase of her project.I really care about STEM for kids in high school and kids in college. Thats why I really worked hard to give so many of my students the opportunity to come down there and see what was happening, Kacena said.

Most of the students were medical students.

Especially for me as Im getting older, theyre going to be my doctors eventually, and I want them to be really knowledgeable. What we learn in the clinic we can translate it to out of the clinic, and vice versa, she said.For more, visit medicine.iu.edu/blogs/bone-healing-in-space/.

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Out of this world: Zionsville doctor sends osteoblast cells into space to study drug effects - Current in Carmel

Man with terminal cancer battles back from coma to marry his childhood sweetheart – Mirror Online

A 26-year-old man told he had just 12 months to live pushed his wedding forward to marry the love of his life.

Dan Cassidy, from Accrington, was diagnosed with aggressive strain of leukaemia in March this year.

He had many things he wanted to do before he died, the the most important one was wedding his soul-mate Darcy Young.

The couple had been together 10 years and were able to push their wedding forward to tie the knot in July after they learned of Dan's tragic terminal cancer diagnosis.

"It was a perfect day," Dan told LancsLive .

"I wasn't feeling too good on the day, I don't know if that was the cancer or the nerves.

"I still had a great time but I couldn't be myself."

Dan was previously diagnosed with cancer in 2016 when he started to feel unwell while at a friend's barbeque.

He said: "I tried to stand up to go to the toilet and I just couldn't. I kept feeling a pain down my legs.

"My friend's wanted me to go out with them but once I was in the taxi I had to go back, I was in so much pain."

He continued: "We went to the hospital the next day and I was told I had leukaemia."

The doctor said that Dan had probably had the condition for two years and that the pain he was experiencing was from his white blood cells fighting aggressively against the cancer.

"He was in so much agony," said Darcy.

"He had dialysis to clean the blood but, whether it was the procedure or not, that caused him to have a bleed on the brain.

"He was transferred to Blackburn hospital and was put into an induced coma."

Things got worse for Dan as the doctors had to cease his cancer treatment while they dealt with the bleed.

But somehow he pulled through.

Following another bleed, brain surgery, strokes, rounds of chemotherapy and radiotherapy, Dan had a stem cell transplant from his mum and was discharged.

"Just before Christmas 2016, I came out of hospital," he said.

"Everything was working fine, I was feeling better and the cancer was in remission."

It was at this point that the 26-year-old decided that he wanted to ask Darcy a special question.

He said: "We have been together for 10 years, so we were due to get married.

"Obviously after I got out of hospital I just thought: life is so short."

Dan took Darcy to her grandparents' favourite place, Shireburn Arms, for a meal while her family decorated her room in secret.

He then gave her a box of chocolates with the words: 'Will you marry me?' iced onto them.

"He asked with chocolates," said Darcy.

"Thats how he asked me to be his girlfriend when I was 15."

The couple planned to marry in November 2019 and Dan continued to have regular check ups every three months.

In March this year Dan came out in a rash and was later told by a doctor that his cancer had returned.

"At the next appointment they said it had come back really aggressively," said Dan.

"They told me I had 12 months to live, that everyone that has had this before doesn't live past 12 months."

Darcy says the consultant was crying when she delivered the news to them.

"It didn't give us much hope," she said.

"She must have to deliver news like that all the time. I think I was in denial at first, I just thought: this can't be happening again."

Once Dan got his diagnosis the wedding became the main focus for the couple and they tied the knot in Clitheroe, in front of their family and friends.

Darcy said: "I didn't know if he would make it to the wedding but he did and it was so lovely.

"It was amazing to have all of our family and friends there to celebrate.

"All the venues and all the businesses we wanted to use made it happen for us - we couldn't ask for anything more."

The couple now live together with their dog Teddy, they are trying to enjoy the present day.

Darcy said: "We just want to seize the moment, every minute we can."

The couple want to share their story in the hope that more people will become aware of leukaemia and sign up to stem cell donor lists.

They continue to raise money for the charity Anthony Nolan who keep a register of stem cell donors.

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Man with terminal cancer battles back from coma to marry his childhood sweetheart - Mirror Online

2 Years Later, Retired Toms River Teacher Meets Bone Marrow Donor – wobm.com

It was more than two years when in a Hometown View segment I shared a story about Lael McGrath who I described at that time as a very active retired 2nd grade teacher from Toms River. Her story centered on learning in August of 2016 that she had acute myeloid leukemia with a recommendation that she undergo a bone marrow transplant as it was her best chance for a full recovery. She had that procedure done in December of 2016 and the segment I aired had to do with a thank you party she was hosting for the family and friends who made up her devoted support group. That party also served as the Be the Match swabbing event as McGrath sought those who might consider being a donor as clearly she knew the importance of that.

So lets move forward to last week when Lael emailed me to say that more than two years later she was going to meet her bone marrow donor in person. Actually, let me backtrack just a bit. After McGrath was diagnosed with AML she was referred to the Blood and Marrow Transplant Program at Rutgers Cancer Institute of New Jersey and RWJ University Hospital where they determined she was a candidate for a stem cell transplant. Unfortunately, none of her five siblings were a match so through the help of RWJ and the Be the Match donor registry the search begana successful one. As I said earlier McGrath had the surgery in December of 2016 and now almost three years later she is in remission and the grandmother of six has returned to that active lifestyle which includes running and yoga.

Now I can go on with the update. As in cases like this, the identity of the donor must remain anonymous for two years and after that period Lael learned that her lifesaver was 21-year old Wiebke Rudolph of Germany who placed herself on a donor registry at the age of 18. The two began communicating and last week just before McGraths 68th birthday they met face-to-face in what was an emotional get-together. Rudolph stayed at McGraths Toms River home and they were treated to a special reception last Friday at the hospital in New Brunswick which also included Laels doctors and other members of her care team.

Clearly Wiebke has now become an unofficial member of the McGrath family and this is one of those stories with a very happy ending. It also brings added attention to the importance of being a donor and for more you can visit http://www.bethematch.org.

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2 Years Later, Retired Toms River Teacher Meets Bone Marrow Donor - wobm.com

March to fight multiple myeloma scheduled this weekend – BlackburnNews.com

http://www.lasalle.ca By Adelle LoiselleSeptember 28, 2019 6:00am

Among the people taking part in this weekends Myeloma March in LaSalle, is Jennifer Radjenovich. She is doing it for her father.

Guido Vetorello was given just three years to live after he was diagnosed with multiple myeloma, but four years later he continues to do what he loves; play with his grandchildren, watch baseball, and travel with his wife.

Trouble started in 2015 when he was treated for anemia when he could not shake unusual fatigue. Unfortunately, the treatments did not work, and his family feared something else was wrong with him.

They were right.

Blood tests and a bone marrow biopsy came back positive for the life-threatening blood cancer affecting plasma cells.

Multiple myeloma or just myeloma is the second most common form of blood cancer. A release from the organizers of this years march said eight Canadians are diagnosed with it every day, and as of yet, doctors do not know what causes it, and there is no cure.

Like Guido, those with the disease can experience fatigue, but also excessive thirst, bone pain, numbness in the legs, nausea, and weight loss.

Unfortunately, Guido did not qualify for a stem cell transplant. Doctors decided it was too risky, but a new drug treatment looked promising, and they were right.

These days, Guido is relatively stable and has exceeded his doctors expectations. Although he undergoes chemotherapy treatments weekly, he is still around to watch his grandchildren grow.

My dad looks forward to going to his treatments every week because he knows they are giving him more time, said Jennifer Vettorello. In the four years since he was diagnosed, the research has been incredible with so many new treatment options available to patients. It gives me real hope that will be with us for some time.

The Vettorello family will be at the Vollmer Culture and Recreation Complex in LaSalle Sunday morning when the ninth annual march gets underway at 9 a.m.

Fundraising, which supports research, has helped almost double the lives of patients in the past 15 years.

Dr Sindu Kanjeekal, the Multiple Myeloma Clinical and Research Lead at the Windsor Regional Cancer Centre, said life expectancies are continuing on an upward trend.

Were now seeing incredibly promising treatment options that are helping us to stay ahead of the disease, he said. For the first time, we can actually say that were getting closer to finding a cure. Investing in research is critical, which is why raising funds is more important than ever.

Windsor-Essex is one of 28 communities across the country taking part in this years march.

The goal this year is $40,000, but across the country, marches are trying to raise $550,000.

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March to fight multiple myeloma scheduled this weekend - BlackburnNews.com

Taz Believes CM Punk Will Be At SmackDown On Fox Thinks Edge Could Pop Up On AEW Or SmackDown – Fightful

Taz has theories.

CM Punk has been in the headlines for the past week, beginning with a report on Sept. 27 that he had tested on-camera for WWE's upcoming studio show on Fox Sports 1; WWE Backstage. Punk was back in the headlines on Sept. 29 when news broke that he and Colt Cabana had settled their lawsuit.

With so much smoke surrounding CM Punk, former WWE announcer Taz believes a fire is about start.

"I think CM Punk is coming back to WWE," stated Taz on The Taz Show. "I know there's been some scuttlebutt about that and I believe when there's smoke there's fire. I believe he's gonna debut on Fox, without a doubt, on Friday. I believe that. Straight up. They're gonna go full-throttle with Fox."

For what it's worth, Booker T, who is set to co-host WWE Backstage alongside Renee Young, said he knows nothing about Punk testing on-camera for the show.

That wasn't the only theory Taz dropped on his show. On the latest edition of the Edge & Christian Pod of Awesomeness, Edge revealed that he would be stepping away from the podcast for the time being. Taz believes there's more to the story.

"If Edge can still go out there and do it at his age, he looks to be in great shape. If he can still get after it in the ring, I think that's great. This is something I gotta say. I know Edge has been looking into stem cell treatment because it would help his neck," said Taz. "I've heard stuff, that he wasn't medically cleared and apparently WWE's doctors aren't clearing him. But yet, they allowed him to do a spear. I'm a little confused on that. I got a feeling that Edge stopping his podcast, my conspiracy theory is, I think he's cleared by WWE. Or he ends up in another company. We've got a couple of big shows debuting this week. I've got a feeling The Rated R Superstar is gonna pop up somewhere. He pops up in WWE, I do think it would be SmackDown. Or AEW. You never know, he could pop up there."

Edge surprised many in the wrestling world when he not only made an appearance at WWE SummerSlam, but delivered a Spear to Elias. Following the appearance, Edge stated on his podcast that he's not as limited as people may think despite his neck injury.

While Edge and CM Punk are not confirmed for SmackDown on Fox, The Rock announced that he will return home on Friday when he appears on SmackDown.

If you use any of the quotes above please credit Taz Show with a h/t to Fightful for the transcription.

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Taz Believes CM Punk Will Be At SmackDown On Fox Thinks Edge Could Pop Up On AEW Or SmackDown - Fightful

Middlesbrough blood donor meets man she saved in Germany – The Northern Echo

A TEESSIDE woman, who three years ago donated blood stem cells to a stranger in Germany, met the man she saved for the very first time as he made the thousand-mile round trip to thank her in person.

Husband, father and grandfather Siegfried Siggi Wahl, 71, from Hattersheim in Germany, was diagnosed with chronic myeloid leukaemia in 2016.

After initial treatment proved unsuccessful, doctors told him his best chance of survival was a blood stem cell donation from a person with identical tissue type.

Luckily for him, just six months earlier his genetic twin, 50-year-old Jackie Wray, who runs a wedding venue in Great Ayton, signed up with donor charity DKMS in 2015 after seeing an appeal.

Shortly after being identified as Siggis perfect match, Jackie began the process of attending medicals and then donating her blood stem cells.

However, back in Germany, Siggis problems were not over. To prepare Siggi for the transfusion, his doctors began to administer a strong dose of chemotherapy to destroy his existing blood stem cells, ready to welcome the new ones, and if he did not receive Jackies healthy blood stem cells quickly, he was unlikely to survive.

As a courier arrived to escort Jackies blood stem cells from London to Frankfurt, news broke of the 2016 terrorist attack in France, and the courier was not able to leave the UK.

After an agonising wait, Jackies blood stem cells finally arrived in Frankfurt, and the transplant successfully went ahead.

UK law states whilst donors and their patients can communicate following the transplant, it must remain anonymous for the first two years. After this, if both parties are in agreement, their identities can be revealed and they can make arrangements to meet.

I loved receiving cards from Siggi, said Jackie. It used to make me cry every time. I would think thank god hes still alive.'

All I knew of Siggi is that he had a son and daughter my age, and a grandson and he used to play ice hockey when he was a young man. Its one of the reasons I was so excited to meet him, to hear his life story.

When he and his wife arrived at my house, there were lots of tears and lots of cuddling. They had made me a photo album with pictures of Siggi during his treatment and they bought me a little angel necklace because they say Im his angel. It was just so lovely and I will treasure it forever.

Siggi added: "It was beautiful. We hugged, and we both cried. It was like a fairy tale.

Jackie will come and visit me and my family in Germany next year to celebrate my birthday. She is just a good hearted person.

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Middlesbrough blood donor meets man she saved in Germany - The Northern Echo

Kevin Mwachiro: Keeper of Stories – Roads and Kingdoms

This week on The Trip podcast: talking African stories, LGBTQ rights in Kenya, and surviving cancer with Kevin Mwachiro.

One of the things, one of the unnerving things, that you first realize as a foreigner visiting Nairobi, is that many of your cohortthose other foreigners landing at Jomo Kenyatta airportseem to be looking right past the people, past the humans of Kenya. They are searching for animals. Nairobi is the worlds busiest transit hub for safari-goers. Theres even a national park inside the city limits, a park with wild warthogs and zebras and giraffes and the rest of the cast from The Lion King.

I am resolutely and proudly not here for a safari. It just feels, well, a little premature, a little colonial, like Id need to be wearing a pith helmet and khaki knee breeches. Maybe on my fifth visit I would go for a walkabout. But Nairobis wildlife will not be ignored. In Karen, the district Im staying innamed after Karen Blixen, who wrote Out of Africa nearbythe birds bring the safari to you. Kestrels and crakes and bee-eaters and bustards, sooty falcons and jacksons widowbirds all circle and sing and their song to me, Im sure, roughly translates as fuck you if you think youre too good for us.

But I stand firm. Itspeople Im most interested in, and if Ive found anything in two decades as a foreign correspondent and daydrinker, its that humans are endlessly fascinating, and occasionally even delightful. Case in point, this episodes guest, Kevin Mwachiroan openly gay athlete in a country where gay relationships are illegal, a survivor of a rare cancer who is also the sunniest person Ive met in ages. Kevin was a guest on one of the last episodes of Parts Unknown, when Bourdain and W. Kamau Bell came to Kenya, and it is my distinct human pleasure to have him, like Tony and Kamau before him, on this show.

Here is an edited and condensed transcript from my conversation with Joshua. Subscribers canlisten to the full episode here. If youre not on Luminary yet, subscribe and listen (and get a 1-month free trial) by signing uphere.

Nathan Thornburgh: All right, so this coffee is great. This is exciting. And I remember Colombians, God love them, make incredible coffee, Juan Valdez on down, but the national passion was instant coffee, and it was always very confusing. But its one of those things where you have this really valuable commodity, easy to export, and somehow I think its true in a lot of places that make the best coffees in the world where the average person is like, Well, Im not going to compete in the global market for these high quality beans. Im going to just be happy with the instant.

But what is Kenyan coffee drinking culture like? Is there some proportion of the population that recognizes that Kenya makes some amazing coffee and rolls with that?

Kevin Mwachiro: The thing with Java House, they make Kenyan coffee accessible to Kenyans, so to speak. Id say maybe middle-class Kenyans. Before that, we were getting high on instant coffee. You were paying a pretty penny for coffee. Then Java opened up and they had baristas there making coffee, good food as well, and youre like, Yeah, its not too bad.

Thornburgh: Yeah.

Mwachiro: But we are a tea-drinking nation.

Thornburgh: So coffee is still the number two?

Mwachiro: Coffee is number two. You go anywhere, people will offer you tea first. And not just teabag tea, but brewed tea with milk and that is it. Coffee, a smaller proportion of people drink coffee, and especially black coffee.

Thornburgh: So, I have been internet stalking you in your various talks and interviews. You have a very entertaining and interesting media profile, I guess you would say.

Mwachiro: Yeah. Entertaining is an interesting word to use.

Thornburgh: A lot of it is the kind of stuff that would give me pause: Getting up on stage, single person, telling a story, trying to hold an audience, and you do it really well, and Im interested in how you got into that. How did you decide, or maybe it just sort of fell into place, that this is what you were going to do for a living?

Mwachiro: I recently took on that label of a storyteller. I think this comes from my time at the BBC, and Ive told people this, I consider myself a custodian of peoples stories, even as a journalist. People gave me their stories and I told them to the wider world. I love hearing peoples stories, so I think through everything as a journalist, as an activist, as a podcaster, as a cancer survivor, and telling my own story, I think life handed me what Id been avoiding for a very long time, and now find myself doing it and people actually say I tell stories pretty well.

Thornburgh: Why had you been avoiding it?

Mwachiro: I love and I dont love being on stage. I dont like the attention, but I know once Im on stage I become a whole new, confident person, and I feel comfortable. And people, every time Im up on stage, were like, You are comfortable there. I used to act once up on a time and yeah, the stage is also home and Im now doing this. I think over time, its a question of valuing yourself, its been a journey to actually get here, and valuing my own story and realizing that I have a story to tell. And was it two, three years ago I gave a talk on, its like a Ted version of Kenya called Engage, and I spoke about finding my voice and that, I think, was a turning point for me. I used to moderate quite a bit before that, professionally, but now being on stage and telling people my own story and actually saying, This is me finding my voice, and sharing it and not feeling ashamed about whatever I have gone through has landed me now here with you.

Thornburgh: Yeah. Lets not make than an end point. This is a humble detour.

Mwachiro: And I realized I like sitting in front of a mic. When I used to work at the BBC, one of the requirements of the work as a journalist was to perform in front of a microphone and on camera. And I realized this is cool stuff, man. I do like cams, I do like microphones, I love audio, I love sound.

I believe in the spoken word.

Thornburgh: Well, lets talk about that. Obviously this is a medium that weve jumped into with great enthusiasm in podcasting. What is the state of podcasting in Kenya? Is it a word that people recognize or is your audience both kind of local and international? How do you look at podcasting in particular?

Mwachiro: Its very interesting you should say that. As I was buying coffee, I met another podcaster, a guy called Armani, and he

Thornburgh: Thats a very Brooklyn scene right there.

Mwachiro: Yeah.

Thornburgh: Here we are at the coffee shop, just a couple podcasters. All right.

Mwachiro: And he recently got into podcasting as well. He wants to bring other podcasters together. I would say its a very Nairobi-centric thing, and very middle class.

I wanted to get back into radio at one time. Id missed audio. I wanted to come up with content, spoken word, and when I talked to people about it, they were like, You should go into podcasting. Im like, No, I want to go back into mainstream radio. And then after some time I figured this might be my avenue, going into mainstream radio. I believe in the spoken word Whats the term we used to use? Anyway, spoken word radio. Im a big fan of that, NPR, BBC.

And thats my background. And I just like storytelling. I figured this is a way of getting Kenyans to listen, but I want to go mainstream. But after some time I realized, speaking to other podcasters, that this just might be an avenue to explore.

Thornburgh: Right.

Mwachiro: I saw it as very niche. As you know, everyones podcasting in the States, in Europe, and its not quite herethe audiences still listen to radio.

Thornburgh: Yeah.

Mwachiro: And commercial radio. And I love public service radio. I really do. And I wanted to go back into that, but that didnt quite happen. Then I started listening to podcasts, started meeting other Kenyan forerunners, forerunner podcasters, and liked what I was doing. I realized this is something that I could do. I started buying kits, good kits, listening to stuff on YouTube, tutorials, I rented quite a number of those, and came up with content. Hence, Nipe Story. Initially I wanted to have full podcasts, then after just trying I realized this is a lot of work, so I scaled down to Nipe Story, which is my podcast. But in general its a very urban thing here in Nairobi. People are beginning to recognize what it has and coming up with a lot of niche content.

Thornburgh: Yeah. Thats the thing about the promise of podcasting. You can find your audience and it doesnt have to be that big, but they can be with you deeply because they can find something thats just specific for their taste. I also, from my short time here in Nairobi, I see tremendous opportunity in podcasting because its all about cars and traffic

Mwachiro: Absolutely.

Thornburgh: and the commute.

Mwachiro: Yeah.

Thornburgh: So, you have so many human hours in the car.

Mwachiro: You have already an audience sitting in Nairobi traffic waiting to listen to stuff.

Thornburgh: Waiting for Nipe Story. So tell me about that show, what is it trying to do and how are you getting that done?

Mwachiro: Nipe Story is just trying to get people into listening to stories, Kenyan stories, African short story fiction. I love stories. I love reading fiction and yet again, I love listening to spoken word and this was my way of just getting involved in that. It started in, I think, December or November 2017.

Mwachiro: So I said, This is amazing, and its a simple goal, mate. Just to make people love listening to stories. And theres a lot of African creative writing going out there and Im hoping to provide a platform for that, and also for a lot of queer writing that doesnt get a platform, especially in this form. So I just want to do that with Nipe Story. I would love Nipe Story to have a Pan-African feel.

Mwachiro: First of all.

Thornburgh: So they could go across the continent and not just be for Kenyans.

Mwachiro: Absolutely. And sometimes when I look at the stats you get people listening in South Africa. But the thing that surprised me, theres a huge North America audience and a British audience as well, that surprises me.

Thornburgh: Yeah. I dont know. I could see the appeal, especially because one, theres a huge diaspora and two, it is a different Ive gotten to listen to some of the episodes and its beautiful in the way that the concerns are just different, the dialect, the accents are different, its transporting in some way. If these were presented from a local perspective in the States, you could have the same mission, the same mandate, but its just very different in the way that it plays and sounds and listens, and you can lose yourself in it.

Mwachiro: Thank you.

Thornburgh: And its interesting, I remember you did an interview in Berlin where you were talking about the flip side of thatparticularly talking about the context of, I think, queer filmwhere you were saying there are some really great films that you saw at the Teddys, where you were a judge, but that they didnt necessarily speak to you. It was just a different experience, because these are European or American filmmakers. That was the sense that I got from that, and there is a way where your experience just does have a local identity to it, right? I mean, its a very Kenyan thing, even though you have common cause with people who are trying to do fiction podcasts, with queer activists, with people in different countries, but your experience is going to be your own, and fairly specific here. So, Im interested in getting a sense from you, taking your temperature on where Kenya is at right now in that particular realm, in queer activism. It seems like a tough game right now.

Mwachiro: People say it is. I dont consider it a really tough game, because weve been here a long time, so were used to this. I had drinks with a friend yesterday whos visiting also from the States and he said, It must be tough being gay, and its a question these days I dont know how to answer. Because Im just doing my thing.

Its waking up Kenya to the reality that queer people are here and theres nothing you can do about it and were as Kenyan as you are.

Thornburgh: Youve always been here.

Mwachiro: Yeah, Ive always been here. Some of my girlfriends are like, Who comes up with single guys? I look at my phone book and Im like, I dont know single guys and if theres any single guys here, theyre dicks and I dont want to introduce you to them. My phone book is full of queer men and women. And Ive normalized that existence here.

Thornburgh: Yeah.

Mwachiro: But the fact that we lost the case in court that was trying to decriminalize gay sex. That was hurtful, that was painful.

Thornburgh: Yeah. I spoke with Wanuri about this too and I think especially for, its a three-year legal battle, but even longer than that, just an entire life of wishing this to be true.

Mwachiro: But the fact that we were actually in courtyou have to look at the positives. I remember some of the comments that I got on my page: Were not coming to Kenya. Were going to boycott. Im like, Why? Weve been in this space for quite a while and to find that 10, 12 years ago we never even thought that we would be in court.

Thornburgh: Yeah.

Mwachiro: But the fact that on the 24th of May, people showed up in court from all over, didnt care about the media glare, didnt care what people thought, but we were in court, mate.

Thornburgh: Yeah.

Mwachiro: That was powerful. And even before that, the first time they postponed it, we had activists come in from Uganda, Tanzania, and Nigeria. Such was the magnitude of what we were doing. And I dont think it will stop us. The fact that now people know that queer people do exist in Kenya. Theyve always known, but the fact that we are coming out strong, were waving the flag next to the Kenyan flag, and we are your brothers, your sisters, your sons, your daughters, your fathers, your husbands, your wives. Its sort of waking up Kenya to the reality that queer people are here and theres nothing you can do about it and were as Kenyan as you are.

So I think the space now and being involved with the Gay and Lesbian Coalition of Kenya and talking to people, its now wanting to move now to dialogues and getting Kenyans to come out in support of us. I feel weve been preaching to the choir for quite a while and its now engaging other members of society and saying, Yeah, you know, this is who we are. What do you want to know about us? How can you help? So that when we do go back to court, wed have other people speaking for us as well and not just ourselves.

Thornburgh: Yeah.

Mwachiro: That would be great. I mean if you look at the case, Botswana luckily won theirs and people were making direct comparisons and you cant look at it that way. This is the jealous coming up, its a very simplistic way of looking at life. That story is not that simple.

But the fact that I was in Botswana last year and the deputy mayor, whos a man living with albinism, came and opened the largest Pan-African LGBT conference that had happened on the continent. The fact that he was there was a huge thing. And I remember sitting there, like would we even get someone from the city coming to attend one of these?

Thornburgh: Yeah, you dont think Mike Sonkos showing up?

Mwachiro: No, I dont think so. I dont think so.

Thornburgh: Your entertaining rapper turned [governor] of Nairobi.

Mwachiro: No, lets not go there. He vexes my spirit, man.

Thornburgh: Mike Money.

Mwachiro: Thats how low we can go as a country.

Thornburgh: So yeah, that idea of building some sort of bridges to other parts of society, so youre not out here fighting alone.

Mwachiro: Absolutely. And then the fact that the President of Botswana gave out very positive statements about homophobia, saying that we cant be in this space and other people have spoken. We have a president who still describes us as non-issues.

Thornburgh: Right.

Mwachiro: So we need to get them to move from non-issues, but I keep on saying almost everything in Kenya is a non-issue. Thats why we are the way we are. So weve just been lumped with everything else. Fight corruption, not an issue. You know?

What do I have to lose now? My shit is out there. I think thats the way you take power from people.

Thornburgh: So many amazing, pressing issues that are actually non-issues.

Mwachiro: Exactly, so when that happened, and then I talked, and people were like, Oh, arent you annoyed? I said, No, Im not annoyed. The truth is, a lot of things that should be dealt with in the country that weve made non-issues, and we have been put into that category of non-issues with everything else.

Thornburgh: So you have joined the mainstream then by becoming a non-issue.

Mwachiro: We have, exactly that. So thats where the space is at. Im just hoping that the ruling has just made us as a movement stronger.

Thornburgh: Yeah.

Mwachiro: Will make us be very introspective in how our strategy going forward will be. And for me personally, I know its made me bolder, totally unapologetic about what I feel and the gay shit Im putting out there on my face.

Thornburgh: The Supreme Court has unleashed the wave of gay shit from Kevin.

Mwachiro: I wrote an article thats going up on this platform called Yellephant. Theyve been very kind in giving us an opportunity to put queer stories out there, two of my articles there, and Im like, Yes, we need it. And as a journalist Im taking I used to be slightly apologetic about it and Im like, Im just going to put stuff, Im just going to put the good journalist I think I am into this area where my energies are and where my life is involved in.

Thornburgh: Yeah.

Mwachiro: And come up with good journalism talking about queer Kenyans.

Thornburgh: Yeah.

Mwachiro: And what it is to be a queer Kenyan in Kenya.

Thornburgh: When you, I think it was a film festival or some sort of forum here that you were involved in that had the tag line Shame is a luxury we cant afford.

Mwachiro: Absolutely.

Thornburgh: But thats that kind of thing. Because certain things are stacked against you, you actually have to be bolder and brighter and kind of more out there. That seems to be your perspective on it.

Mwachiro: I was telling someone, what do I have to lose now? My shit is out there. I think thats the way you take power from people. Ive hung up my dirty laundry. I dont think its there, I just use that expression. I hang it there. So you can see Ive taken the power away from you.

Thornburgh: Right. Right. This sort of constant, ongoing This is the experience I think that gay people have had for a long time in the States. Its like this daily blackmail.

Mwachiro: Exactly. Exactly. Ive gone through a process and a journey, Nathan, where I didnt like myself pretty much, I didnt think I was worth something to a point where I know what Im worth and Im happy about who I am in this space. Life has dealt me numbers, thrown lemons at me and Ive made lemonade and Im dealing with that and moving on. I was telling a friend yesterday, You only have one life.

Thornburgh: Right. How are you going to spend it, huh?

Mwachiro: How are you going to spend it? And if this life is going to be used trying to make it easier for other queer individuals in Kenya, so be it, mate. And not just that, but also just trying to make a world, the world a better place for other folk, man.

Thornburgh: Yeah. I mean this is the thing also that I feel people understand very little of. I mean, clearly by some of the conversations were having in the United States, rights for LGBT, justice or rights for minority groups, its not even about them. Its about you and what kind of country youre going to be. And Im sure Botswana is looking at it holistically as well as all these goals they have as a nation, which include development, increased tourism, equal standing on the world stage, all of these things are hurt when they diminish the rights of some large percentage of their population. We have that same conversation in the States. Its not about being nice to gay people. Its about your quality of country.

Mwachiro: Absolutely. I like that. And just being nice to all people. Being nice to women. I think we as a country could do a much better job in being nicer to our women. Slight digression here, we still havent fulfilled that constitutional quota that requires 25% representation of women.

Thornburgh: Wow. Which isnt a big number.

Mwachiro: Its not a number, but

Thornburgh: Its not totally proportionate, but yeah, even that is beyond reach.

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Kevin Mwachiro: Keeper of Stories - Roads and Kingdoms

Mansfield’s Daniel Maberry has returned to coaching during battle with cancer, but his stay on sideline will be brief – The Dallas Morning News

Mansfield football coach Daniel Maberry was forced to take an 11-month break from coaching games as he battled an incurable disease.

The last two weeks, Maberry was finally feeling well enough that he could pause his fight with cancer and coach his first two games of the season. His return to the sideline will be brief, however.

The 47-year-old Maberry said Tuesday night that he hopes to coach Friday when Mansfield (1-3, 0-1 District 7-6A) plays South Grand Prairie (2-2, 1-0) at 7:30 p.m. at the Gopher-Warrior Bowl in Grand Prairie. But that will be his last game of the season, as he prepares to begin eight weeks of treatment in early October, with the first two weeks spent in the hospital.

"I plan to be on the sideline [Friday], but it will depend on what I can do," he said.

Maberry coached last Friday after getting radiation treatment earlier in the day. "It zaps you," he said, but he handled the head coaching duties while interim coach Greg George returned to his role as offensive coordinator.

"It was awesome," said Maberry, who had to take a break from coaching last season after Mansfield's game against DeSoto on Oct. 12, 2018. "Having an opportunity to coach my kids and be excited with them. I had been away from it for too long."

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Maberry was diagnosed with Stage 4 lymphoma in January 2018, but in June of that year doctors told him that his disease was basically in remission, and had become "inactive." That wouldn't be the last time he would hear that, only to see the lymphoma return.

Three to four months later, Maberry's disease had morphed into an aggressive form of non-Hodgkin's lymphoma called diffuse large B-cell lymphoma. After undergoing chemotherapy, Maberry was told in March that he was clear of it, that it was back in remission.

Maberry had a stem cell transplant in April, only for doctors to detect a small spot on his rib cage in early August. He started radiation treatment last week, but he's not giving up and credits his family and the Mansfield community with helping him throughout the grueling ordeal.

"God has used a lot of people to pick me up," he said. "It has been a kick in the gut every single time. It has been incredibly hard, but I can't allow this to rob me of my joy. I feel like I am going to get better. My faith is strong."

Twitter: @DMNGregRiddle

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Mansfield's Daniel Maberry has returned to coaching during battle with cancer, but his stay on sideline will be brief - The Dallas Morning News

What’s on TV Monday: The season premiere of ‘Bull’ on CBS – Los Angeles Times

SERIES

The Neighborhood Its been a year since Dave and Gemma (Max Greenfield, Beth Behrs) moved in, and now Dave wants to take a more active role in Calvins (Cedric the Entertainer) annual Yardecue event in the season premiere of the family comedy. 8 p.m. CBS

The Voice Gwen Stefani joins returning coaches Kelly Clarkson, John Legend and Blake Shelton on the first night of blind auditions in the season premiere. 8 p.m. NBC

Dancing With the Stars This new episode features the first elimination of the season. 8 p.m. ABC

9-1-1 What is expected to be a routine traffic stop uncovers a kidnapping in progress. Angela Bassett and Oliver Stark star in the season premiere with guest stars Tracie Thoms, Gavin McHugh, Bryan Safi and Christopher Cousins. 8 p.m. Fox

Country Music Will the Circle Be Unbroken? (1968-1972), the next installment of Ken Burns documentary series, chronicles the musical genre during the Vietnam war era. Kris Kristofferson, Bob Dylan and The Byrds go to Nashville to record. 8 p.m. KOCE and KPBS

Bob Hearts Abishola Billy Gardell stars as Bob, a Detroit businessman who lands in the hospital from the stress of running a family-owned compression-sock company. He starts to fall for Abishola (Folake Olowofoyeku), the Nigerian immigrant who is his cardiac nurse, and resolves to win her over. Christine Ebersole, Matt Jones and Maribeth Monroe (The Good Place) costar. 8:30 p.m. CBS

All Rise Simone Missick stars as a newly appointed judge who runs her court in her own unique way. Marg Helgenberger, Lindsay Mendez and Ruthie Ann Miles costar along with Wilson Bethel, Jessica Camacho and J. Alex Brinson. 9 p.m. CBS

Halloween Baking Championship John Henson kicks off the fifth season of this holiday-themed baking competition with a challenge for the eight bakers to create scary skeleton desserts. Carla Hall, Katie Lee and Zac Young are the judges. 9 p.m. Food Network

A Very Brady Renovation Steve and Leanne Ford team up with Christopher Knight and Eve Plumb to build out the kitchen and family room on the first floor. Also, the Brady backyard gets artificial turf. 9 p.m. HGTV

Prodigal Son This new crime drama stars Tom Payne (The Walking Dead) as a gifted criminal psychologist whose qualifications for helping the New York Police Department solve crimes include his father (Michael Sheen), a serial killer known as The Surgeon. Halston Sage, Bellamy Young (Scandal) and Lou Diamond Phillips also star. 9 p.m. Fox

Bull Distracted by his looming role as a new father, Bull (Michael Weatherly) lets his work at his jury consulting firm suffer, and Benny (Freddy Rodriguez), his top attorney, has quit in protest of some of Bulls recent and ill-advised romantic liaisons. Geneva Carr and Christopher Jackson also star. Yara Martinez and David Furr guest star in the season premiere. 10 p.m. CBS

Bluff City Law After the death of her mother, an attorney (Caitlin McGee) accepts an invitation from her estranged father (Jimmy Smits) to rejoin his prestigious Memphis law firm in this new legal drama. They try to reconnect as father and daughter while meshing their dramatically different courtroom styles. Scott Shepherd, Barry Sloane, Michael Luwoye, MaameYaa Boafo, Stony Blyden and Jayne Atkinson also star in this new drama. 10 p.m. NBC

The Good Doctor The third season of this medical drama opens the day after Shaun and Carlys (Freddie Highmore, Jasika Nicole) first date, which was, from his perspective, a disaster. 10 p.m. ABC

CBS This Morning Oprah Winfrey; Kevin Frazier. (N) 7 a.m. KCBS

Today (N) 7 a.m. KNBC

KTLA Morning News (N) 7 a.m. KTLA

Good Morning America (N) 7 a.m. KABC

Good Day L.A. Billy Bush (Extra Extra). Neurosurgeon Dr. Robert Louis; Elizabeth Wagmeister, Variety; Jerry Springer (Judge Jerry); Marcellas Reynolds. (N) 7 a.m. KTTV

Live With Kelly and Ryan John Goodman (The Conners); Robert Iger, Disney. (N) 9 a.m. KABC

The View Robert Iger, Disney. (N) 10 a.m. KABC

Rachael Ray Tom Payne (Prodigal Son). (N) 10 a.m. KTTV

The Wendy Williams Show (N) 11 a.m. KTTV

The Talk (N) 1 p.m. KCBS

The Dr. Oz Show A fertility clinics mistakes result in multiple women giving birth to other couples babies. (N) 1 p.m. KTTV

The Kelly Clarkson Show Trisha Yearwood; Erin Moriarty (The Boys); chef Keith Garrett. (N) 2 p.m. KNBC

Dr. Phil A private investigator says he has new information about the car crash in which Princess Diana died. (N) 3 p.m. KCBS

The Ellen DeGeneres Show Oprah Winfrey; Lil Nas X performs. (N) 3 p.m. KNBC

The Real Blac Chyna (The Real Blac Chyna); guest co-host Amanda Seales (book Small Doses). (N) 3 p.m. KTTV

The Doctors Employers pushing stem-cell treatments to workers; an Instagram body-slimming trend. (N) 3 p.m. KCOP

To the Contrary With Bonnie Erb Debate week. 6 p.m. KVCR

Amanpour and Company (N) 11 p.m. KCET; midnight KVCR; 1 a.m. KLCS

Conan Jeffrey Dean Morgan. (N) 11 p.m. TBS

The Tonight Show Starring Jimmy Fallon (Season premiere) Gwen Stefani; Ben Platt; Zac Brown Band performs. (N) 11:34 p.m. KNBC

The Late Show With Stephen Colbert Paul McCartney. (N) 11:35 p.m. KCBS

Jimmy Kimmel Live 11:35 p.m. KABC

The Late Late Show With James Corden Rob Corddry; Lake Bell; Anna Drezen. (N) 12:37 a.m. KCBS

Late Night With Seth Meyers Liza Koshy; Jade Bird performs. (N) 12:37 a.m. KNBC

Nightline (N) 12:37 a.m. KABC

A Little Late With Lilly Singh (N) 1:38 a.m. KNBC

NFL Football The Chicago Bears visit the Washington Redskins, 5 p.m. ESPN

NHL Preseason Hockey The Anaheim Ducks visit the Kings, 7:30 p.m. Fox Sports Net

For more sports on TV, see the Sports section.

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What's on TV Monday: The season premiere of 'Bull' on CBS - Los Angeles Times

Eyes on the Prize: The CBC Fights Blindness During Sickle Cell Awareness Month – The Root

Blood is the jet fuel of the body. It helps you jump, run, breathe and move with ease through the world. So imagine what happens if that fuel isnt running smoothly through your body. Its clogging your system, straining every valve, organ and extremity as youre slowly starved for air. That sounds excruciatingly painful, and thats exactly what 1 in 365 African Americans deal with who suffer from sickle cell anemia.

September is Sickle Cell Awareness Month and its common throughout the month to see awareness raising articles about famous people living with sickle cell, like actor Larenz Tate (Power), T-Boz from TLC, former Giants running back Tiki Barber or even Howard University President Wayne Frederick. You seldom see stories about what actions are being taken by scientists and researchers to make sickle cell disease and the dozens of medical consequences that stem from it a thing of the past. Thats why Rep. Sanford Bishop (D-Ga.) and the Congressional Black Caucus have decided to do something about it.

The reason most peoples blood runs smoothly through their bodies is that red blood cells are round and smooth, which allows them to slip through blood vessels with ease. For those with sickle cell, red blood cells have hardened into a C shape, (thus the sickle name); they clog the bloodstream and choke off vital oxygen to organs, causing pain, organ failure and, in some cases, death.

When a child is diagnosed with sickle cellsometimes even toddlersdoctors often warn parents about the childs potential limitations and prescribe proper therapy and medication to make sure he or she lives a long and healthy life. Unfortunately, like many other areas of the American healthcare system, not enough attention is paid to a disease that primarily affects African Americans, and many of the other consequences of sickle cell get missed.

Sickle cell retinopathy is overlooked by most pediatricians but even some specialized doctors, says Morton Goldberg, the director emeritus of the Wilmer Eye Institute at Johns Hopkins University in Baltimore. Dr. Goldberg has the tone of a man who has been in the trenches for years and is finally seeing a turning point in the war. He has been working on sickle cell retinopathy for over 50 years and talks about how the disease, because it is most common in African Americans, is often overlooked even though the consequences are utterly dire and easily preventable.

For the layman, sickle cell retinopathy is when the diseased blood cells cause clogging in the blood vessels around the eye, which can lead to a host of other complications, the most serious being blindness. There is equipment out there, even training that can help doctors diagnose sickle cell retinopathy early to give parents and patients the tools they need, but that need usually goes unmet. Why?

Theres been insufficient funding for the last 30 to 40 years, says Dr. Goldberg, which is why hes on board to promote H.R. 2620, the Faster Treatments and Cures for Eye Diseases Act proposed by Bishop.For far too long, we have had federally funded research sitting on the shelf, waiting for private investors to put it into practice, Congressman Bishop said. When it comes to turning research into cures, we must seek new ways to tackle old problems. The Eye bonds created by the Faster Treatments and Cures for Eye Diseases Act will give health research the boost it needs to help Americans. These bonds will fund research that has the potential to deliver new treatments for a range of conditions, including macular degeneration, glaucoma, blindness caused by diabetes and sickle cell disease, and many others. And this is just the first step, if this pilot program is successful, a similar approach could be used to support groundbreaking research for other conditions such as cancer, Alzheimers and Parkinsons disease.

Money is, of course, one of the main reasons why research into preventing blindness caused by other diseases often doesnt go anywhere or doesnt go far enough, especially when those suffering are from underserved communities to begin with. On top of blindness caused by sickle cell, retinopathy from diabetes causes 17 percent of vision loss in African Americansand blindness caused by glaucoma is twice as likely (3.4 percent) in African Americans as it is in white Americans (1.7 percent).

A lot of this is about access to care, says Dr. Carlton Haywood, a professor of biomedical ethics at Johns Hopkins. The bill proposed by Rep. Bishop has particular resonance with Haywood since he actually has sickle cell and has spent much of his career focusing on the impact of care and access for blood-borne diseases. Haywood, who was also a former patient of Dr. Goldberg, points out that even when a doctor may advise a family to look into the possibility of retinopathy, without funding for even the diagnosis, preventive or corrective surgeries could be astronomical.

All too often, the press and regular voters talk about all the things that Congress doesnt do. In the process, we forget about the kind of day-to-day grind work that members of Congress do every day to help people not just in their districts but across the nation.. The Faster Treatment and Cures for Eye Diseases Act is the kind of thing that everyone says they want Congress to pass (who isnt against blindness?), but it currently sits in the Energy and Commerce Committee, waiting for a vote in committee so that it can be voted on by the entire House. This is the kind of bill America wants to see, and this bill, both figuratively and literally, can make that happen.

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Eyes on the Prize: The CBC Fights Blindness During Sickle Cell Awareness Month - The Root