Stem cell treatment holds hope for better stroke recovery

A new first-of-its kind pilot study has revealed that stem cell treatment can significantly improve recovery from stroke in humans.

The therapy uses a type of cell called CD34+ cells, a set of stem cells in the bone marrow that give rise to blood cells and blood vessel lining cells. Rather than developing into brain cells themselves, the cells are thought to release chemicals that trigger the growth of new brain tissue and new blood vessels in the area damaged by stroke.

The patients were treated within seven days of a severe stroke, in contrast to several other stem cell trials, most of which have treated patients after six months or later. The Imperial researchers believe early treatment might improve the chances of a better recovery.

Dr Soma Banerjee, Consultant in Stroke Medicine at Imperial College Healthcare NHS Trust, said that the treatment appeared to be safe and that it's feasible to treat patients early when they might be more likely to benefit.

However, it's too early to draw definitive conclusions about the effectiveness of the therapy and more tests to work out the best dose and timescale for treatment before starting larger trials, she further added.

The study is published in the journal Stem Cells Translational Medicine.

(Posted on 09-08-2014)

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Stem cell treatment holds hope for better stroke recovery

Cell Separation Technologies Market Expected to Reach USD 3.3 Billion Globally in 2019: Transparency Market Research

ALBANY, New York, August 8, 2014 /PRNewswire/ --

According to a new market report published by Transparency Market Research "Cell Separation Technologies Market (Technology: Gradient Centrifugation, MACS and FACS; Application: Stem Cell Research, Immunology, Neuroscience and Cancer Research) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019", the global cell separation technologies market was valued at USD 1.7 billion in 2012 and is expected to grow at a CAGR of 9.7% from 2013 to 2019, to reach an estimated value of USD 3.3 billion in 2019.

Browse the full Cell Separation TechnologiesMarket Report at http://www.transparencymarketresearch.com/cell-separation-technologies.html

Cells play an important role in the field of microbiology, biotechnology and bioscience which have wide application in pharmaceuticals and healthcare industries. Taking into consideration the increasing demand for cell therapies to treat chronic diseases, research activities targeting cellular therapies have increased tremendously in the last decade. Growth in cell therapy oriented research has escalated demand for cell separation technologies worldwide.

Out of the various types of technologies available in the market, magnetic activated cell sorting (MACS) technology was the major technology segment in 2012, with market share of more than 42.5% in the global cell separation technologies market. Further, fluorescence activated cell sorting (FACS) technology is estimated to capture the market share of rest of the technology segments during the forecast period owing to increased adoption of fluorescence activated cell sorting technology into cell purity sensitive research areas. It is estimated that the global FACS market will reach USD 1,078.5 billion in 2019 growing at a CAGR of 13.9% from 2013 to 2019.

Stem cell research was the major application segment by revenue in the cell separation technologies market in the year 2012. Rising demand for cell therapy and predictable potential of stem cells in the chronic disease treatment have raised the stem cell research activities globally and thereby has resulted in swift growth of the overall cell separation technologies market.

Related & Recently Published Reports by Transparency Market Research

Geographically, North America was the market leader in the global cell separation technologies market in 2012 mainly owing to availability of research funds, highly developed research infrastructure and higher rates of adoption of newer technologies in the practice. Further, growth of the North American cell separation technologies market is driven by factors such as technological advancement, higher healthcare spending and availability of supportive economy to conduct research. In addition, Asia-Pacific is estimated to be a potential market due to rapidly developing healthcare infrastructure on the basis of rapidly increasing medical tourism industry in the Asian countries, mainly in India and Malaysia, increased government support for biotech research and development and large pool of patients suffering from chronic diseases. Some of the key participants operating in this market include BD Bioscience, EMD Millipore, Mitenyi Biotec GmbH, and STEMCELL Technologies and Life Technologies (Thermo Fisher Scientific, Inc.).

The global cell separation technologies market is segmented as follows:

Cell Separation Technologies Market, by Technology

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Cell Separation Technologies Market Expected to Reach USD 3.3 Billion Globally in 2019: Transparency Market Research

Stem cell hope for stroke victims

Brain damage caused by strokes could be repaired through the use of stem cells in a discovery that may revolutionise treatment, a study has suggested.

Researchers at Imperial College London found that injecting a patient's stem cells into their brain may be able to change the lives of the tens of thousands of people who suffer strokes each year.

Their results have been called "one of the most exciting recent developments in stroke research".

Doctors said the procedure could become routine in 10 years after larger trials are conducted to examine its effectiveness.

Researcher Dr Paul Bentley, from the college's Department of Medicine, said: "Currently, the main form of treatment is an unblocking of the blood vessel, and that only helps one-third of the patients who are treated and only 10 per cent are eligible anyway. So we said, 'What about the other 90 per cent?' "

The team targeted patients who had suffered severe strokes involving a clot in a blood vessel in the middle of the brain. Typically, there is a high mortality rate in these patients and those who survive are often severely disabled, unable to walk, talk, feed or dress themselves. The experimental procedure was carried out on five such patients, aged 40 to 70, all of whom showed improvement over the following six months, and three were living independently.

Dr Madina Kara, a neuroscientist at the Stroke Association, said: "This is one of the most exciting recent developments in stroke research. However, it's still early days in stem cell research, but the findings could lead to new treatments for stroke patients in the future.

"In the UK, someone has a stroke every three and a half minutes, and around 58 per cent of stroke survivors are left with a disability."

The experimental procedure involved harvesting the patient's own bone marrow, which was then sent to a specialist laboratory so specific stem cells, called CD34+, could be selected. The patient then has a wire inserted into the area of the brain damage. Once there, the stem cells are released and the wire retracted. During the trials the whole process took half a day, but it is hoped that with refinement it could be reduced.

It is thought the cells work in two ways: by growing into small blood vessels that allow the brain to grow new nerves and brain tissue surrounding them, and by releasing anti-inflammatory chemicals that encourage tissue repair.

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Stem cell hope for stroke victims

Due to a radical new approach by stem cell bank BioEden future generations could be guaranteed a stem cell match

(PRWEB UK) 9 August 2014

Stem cell therapy and treatments continue to move on in finding cures for diseases that in the past were thought to be incurable. The success of stem cell treatment and therapy relies to a great extent on the ability for the patient to have a stem cell match. Although stem cell banking has been available for a number of years, the cost for many has been a barrier.

Specialist stem cell bank BioEden who operate in 21 countries have come up with a solution that brings this potentially life saving opportunity within an affordable range for the majority.

Their aim is to make stem cell therapy an affordable reality and hope that their new approach which includes a low monthly membership option will do just that.

As more and more people bank their children's stem cells for their future use, the problem of finding a stem cell match could become a thing of the past.

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Due to a radical new approach by stem cell bank BioEden future generations could be guaranteed a stem cell match

Edu Manzano considering stem-cell treatment for his back problem

Kasalukuyan daw uma-attend si Edu Manzano ng mga seminar tungkol sa stem cell therapy.

Nagbabalak kasi ang TV host na sumailalim sa nasabing treatment.

Subalit hindi 'tulad ng iba, kung saan pag-iwas sa mabilisang pagtanda ang dahilan, gagawin daw ito ni Edu para sa kanyang problema sa likod.

Sa panayam ng PEP.ph (Philippine Entertainment Portal) at ibang reporters kanina, August 7, sinabi ni Edu, In my case, its for my back because of the accidents that Ive suffered during mga stunts in my 30 years in the movie.

Nagbigay rin siya ng ilang patunay na hindi lamang para sa vanity ang stem-cell treatment.

Aniya, Actually, people are talking about stem cells now.

But there are still misconceptions about stem cells.

You know, its not always about youth.

"Ive seen a friend who had a heart attack.

I have a friend who has failing vision, declared legally blind, in-inject talaga sa mata, nakakakita na siya, nagmamaneho na siya.

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Edu Manzano considering stem-cell treatment for his back problem

Edu Manzano sa planong kasalan nina Luis at Angel: 'I dont think they need any pressure'

Subalit hindi 'tulad ng iba, kung saan pag-iwas sa mabilisang pagtanda ang dahilan, gagawin daw ito ni Edu para sa kanyang problema sa likod.

Sa panayam ng PEP.ph (Philippine Entertainment Portal) at ibang reporters nitong Huwebes, August 7, sinabi ni Edu, In my case, its for my back because of the accidents that Ive suffered during mga stunts in my 30 years in the movie.

Nagbigay rin siya ng ilang patunay na hindi lamang para sa vanity ang stem-cell treatment.

Aniya, Actually, people are talking about stem cells now.

But there are still misconceptions about stem cells.

You know, its not always about youth.

"Ive seen a friend who had a heart attack.

I have a friend who has failing vision, declared legally blind, in-inject talaga sa mata, nakakakita na siya, nagmamaneho na siya.

Unlike what people see about stem cell, instead of retaining your youthful look, it actually addresses certain ailments.

Ilan sa mga personalidad na umaming sumailalim na sa stem cell treatment ay ang aktres na si Lorna Tolentino, ang StarTalk host na si Lolit Solis, at si Senator Juan Ponce Enrile. GIVING FREEDOM TO HIS CHILDREN. Samantala, sinabi ni Edu na dahil sa pagbabago niya ng lifestyle, mas kaya na niya ngayong makipagsabayan sa kanyang mga anak na sina Luis, Addie, at Enzo.

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Edu Manzano sa planong kasalan nina Luis at Angel: 'I dont think they need any pressure'

Yoshiki Sasai Suicide: Japanese Stem Cell Scientist Found Dead In Kobe Facility

A Japanese scientist who was among a team of researchers accused of falsifying the results of two stem cell studies committed suicide Tuesday at a government science institute in western Japan. Yoshiki Sasai, deputy director of the Riken Center for Developmental Biology, was found by a security guard at the Kobe facility with a rope around his neck, the Associated Press reports. Authorities said he had suffered from cardiac arrest and was pronounced dead two hours later.

Sasai, 52, was considered an expert in embryonic stem cell research and co-authored two research papers published in January in the journal Nature that detailed a seemingly groundbreaking method of harvesting stem cells to grow new human tissue. Sasai and lead author Haruko Obokata reported having successfully altered ordinary mouse cells into versatile stem cells by immersing them in a mildly acidic solution. The resulting cells were named stimulus-triggered acquisition of pluripotency (STAP) cells.

The studies were initially praised as being on the cutting edge of stem cell treatment, but were quickly disputed when other scientists could not replicate the experimental procedure. The papers were retracted six months later after the journal found they contained erroneous data, among other flaws.

Scientists at RIKEN Center for Developmental Biology in Kobe are deeply concerned about the allegations regarding the recently reported STAP cells, the center said in a statement released in March. We wish to express our strong commitment to maintaining the highest level of scientific integrity to the public and the scientific community. We are fully aware that trust from the society is crucial for research activities carried out in RIKEN.

The scandal apparently affected Sasais health. Following the initial revelation that the research he was involved in may have been flubbed, he was hospitalized in March for stress, according to Riken spokesman Satoru Kagaya, who told reporters during a televised news conference on Tuesday that Sasai "seemed completely exhausted" when they talked over the phone in May.

Several suicide notes were found on Sasais secretarys desk, according to the Wall Street Journal. The content of the notes has not been made public, but officials said two of the notes were addressed to Riken officials, one of whom was Obokata.

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Yoshiki Sasai Suicide: Japanese Stem Cell Scientist Found Dead In Kobe Facility

Bong Revilla Jr. at Jinggoy Estrada, naalarma sa nangyari kay Lolit Solis

USAPANG CELL at stem cell.

Kuwento ito mismo ni Lolit Solis tungkol sa kanyang ikalawang stem cell treatment sa Germany kamakailan, kasamang muli ang alagang si Lorna Tolentino.

Like the first stem cell treatment she underwent more than a year ago, hindi ikinakailamuch less ikinahihiyani Nay Lolit na amining courtesy of her friend Dra. Vicki Belo ang milyong piso ring halaga ng nasabing medical breakthrough.

Malaki ang iginanda ng kundisyong pisikal ng talent manager-TV host makaraan ng unang gamutan. Mas gumaan daw ang kanyang pakiramdam.

But her diabetesthat manifested when she turned more than 60became burdensome sa puntong kinailangan na niyang mag-insulin. Ito ang itinuturong culprit ni Nay Lolit kung bakit bagamat matagumpay naman ang kanyang ikalawang stem cell treatment ay nawalan siya raw ng malay nang makauwi nat nagpapahinga sa kanyang West Fairview residence.

Dahil naalarma ang kanyang mga kaibigan most specially in showbiz, there was a seemingly endless barrage of phone calls after she regained her consciousness.

A concerned Bong Revillaalso her wardrang her up. Tanong daw nang tanong ang senador kung anong nangyari kay Nay Lolit at kung ano ang kailangan nito.

Moments later, ang nasa kabilang linya naman daw ng telepono ay si Jinggoy Estrada, na noong malamang libre lang naman ang naturang treatment ay ito pa raw ang nanita sa kanya na may halo namang malasakit, Eh, kasi naman, ang hilig-hilig mo sa libre, no! Hayan tuloy nangyari sa yo!

Realizing that Senator Jinggoy had a point, tumawa na lang daw si Nay Lolit.

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Bong Revilla Jr. at Jinggoy Estrada, naalarma sa nangyari kay Lolit Solis

Japanese scientist dies by suicide after stem-cell research scandal

A Japanese researcher at the centre of discredited research that was initially hailed as a potential breakthrough for stem-cell treatment, killed himself after months of stress and exhaustion, officials said on Tuesday.

Yoshiki Sasai, co-author of the high-profile research that had seemed to offer hope for replacing damaged cells or even growing new human organs, was found early on Tuesday at the Riken institute where he worked in Kobe, western Japan, police and the institute said.

It is confirmed as a suicide, said a police spokesman. It was a hanging.

Sasai, 52, had been hospitalized in March for stress and become less receptive to media inquiries during the controversy over the teams research, said Riken spokesman Satoru Kagaya.

The scientist had seemed completely exhausted in their last phone conversation around May or June, Kagaya told a televised news conference.

As deputy director of Rikens Center for Developmental Biology, Sasai supervised the work of lead author Haruko Obokata, which took the world of molecular biology by storm when it was published in the British journal Nature in January.

It was retracted after months of controversy that made front-page news in Japan and tarnished the countrys reputation for scientific research.

The journals editor-in-chief, Phil Campbell, issued a statement in London describing Sasais death as a true tragedy for science and an immense loss to the research community.

Yoshiki Sasai was an exceptional scientist and he has left an extraordinary legacy of pioneering work across many fields within stem cell and developmental biology, Campbell said.

It is very unfortunate that this happened, said the governments top spokesman, Chief Cabinet Secretary Yoshihide Suga. Mr Sasai contributed greatly in the field of developmental biology and was an internationally renowned researcher.

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Japanese scientist dies by suicide after stem-cell research scandal

Japanese scientist stem-cell scientist Yoshiki Sasai commits suicide

Yoshiki Sasai, who was embroiled in a stem-cell scandal, committed suicide He was found with a rope around his neck at science institute Riken in Japan Mr Sasai, 52, was deputy chief of Riken's Center for Developmental Biology He co-authored stem-cell research papers with falsified contents

By Ted Thornhill

Published: 06:20 EST, 5 August 2014 | Updated: 09:29 EST, 5 August 2014

A senior Japanese scientist embroiled in a stem-cell research scandal died on Tuesday in an apparent suicide, police said.

Yoshiki Sasai, who supervised and co-authored stem-cell research papers that had to be retracted due to falsified contents, was found suffering from cardiac arrest at the government-affiliated science institute Riken in Kobe, in western Japan, according to Hyogo prefectural police.

Sasai, 52, was deputy chief of Riken's Center for Developmental Biology.

Tragic:Yoshiki Sasai, who was embroiled in a stem-cell scandal, committed suicide and was found with a rope around his neck at his place of work

A security guard found him with a rope around his neck, according to Riken. Sasai was rushed to a hospital, but was pronounced dead two hours later.

Police and Riken said Sasai left what appeared to be suicide notes, but refused to disclose their contents.

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Japanese scientist stem-cell scientist Yoshiki Sasai commits suicide