Category Archives: Stem Cell Treatment


Stem cell therapy: Facts worth noting – Worldnews.com

The Food and Drug Administration (FDA or USFDA) is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments. The FDA is responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), veterinary products, and cosmetics.

The FDA also enforces other laws, notably Section 361 of the Public Health Service Act and associated regulations, many of which are not directly related to food or drugs. These include sanitation requirements on interstate travel and control of disease on products ranging from certain household pets to sperm donation for assisted reproduction.

The FDA is led by the Commissioner of Food and Drugs, appointed by the President with the advice and consent of the Senate. The Commissioner reports to the Secretary of Health and Human Services. The 21st and current Commissioner is Dr. Margaret A. Hamburg. She has served as Commissioner since February 2009.

The FDA has its headquarters at White Oak, Maryland.[3] The agency also has 223 field offices and 13laboratories located throughout the 50states, the United States Virgin Islands, and Puerto Rico.[4] In 2008, the FDA started opening offices in foreign countries, including China, India, Costa Rica, Chile, Belgium, and the United Kingdom.[5]

The FDA comprises several offices and centers. There are

In recent years, the agency began undertaking a large-scale effort to consolidate its operations in the Washington Metropolitan Area from its main headquarters in Rockville and several fragmented office buildings in the vicinity to the former site of the Naval Ordnance Laboratory in the White Oak area of Silver Spring, Maryland.[3][6] When the FDA arrived, the site was renamed from the White Oak Naval Surface Warfare Center to the Federal Research Center at White Oak. The first building, the Life Sciences Laboratory, was dedicated and opened with 104 employees on the campus in December 2003. The project is slated to be completed by 2013.

While most of the Centers are located around the Washington, D.C., area as part of the Headquarters divisions, two offices - the Office of Regulatory Affairs (ORA) and the Office of Criminal Investigations (OCI) - are primarily field offices with a workforce spread across the country.

The Office of Regulatory Affairs is considered the "eyes and ears" of the agency, conducting the vast majority of the FDA's work in the field. Consumer Safety Officers, more commonly called Investigators, are the individuals who inspect production and warehousing facilities, investigate complaints, illnesses, or outbreaks, and review documentation in the case of medical devices, drugs, biological products, and other items where it may be difficult to conduct a physical examination or take a physical sample of the product. The Office of Regulatory Affairs is divided into five regions, which are further divided into 13 districts. Districts are based roughly on the geographic divisions of the federal court system. Each district comprises a main district office, and a number of Resident Posts, which are FDA offices located away from the district office to serve a particular geographic area. ORA also includes the Agency's network of laboratories, which analyze any physical samples taken. Though samples are usually food-related, some laboratories are equipped to analyze drugs, cosmetics, and radiation-emitting devices.

The Office of Criminal Investigations was established in 1991 to investigate criminal cases. Unlike ORA Investigators, OCI Special Agents are armed, and are not focused on the technical aspects of the regulated industries. OCI agents pursue and develop cases where criminal actions have occurred, such as fraudulent claims, or knowingly and willfully shipping known adulterated goods in interstate commerce. In many cases, OCI will pursue cases where Title 18 violations have occurred (e.g. conspiracy, false statements, wire fraud, mail fraud), in addition to prohibited acts as defined in Chapter III of the FD&C Act. OCI Special Agents often come from other criminal investigations backgrounds, and work closely with the Federal Bureau of Investigation, Assistant Attorney General, and even Interpol. OCI will receive cases from a variety of sources, including ORA, local agencies, and the FBI, and will work with ORA investigators to help develop the technical and science-based aspects of a case. OCI is a smaller branch, comprising about 200 agents nationwide.

The FDA frequently works in conjunction with other federal agencies including the Department of Agriculture, Drug Enforcement Administration, Customs and Border Protection, and Consumer Product Safety Commission. Often local and state government agencies also work in cooperation with the FDA to provide regulatory inspections and enforcement action.

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Stem cell therapy: Facts worth noting - Worldnews.com

[International version] Linda van Laake: "We want to work together to improve stem cell treatment" – Video


[International version] Linda van Laake: "We want to work together to improve stem cell treatment"
Dr Linda van Laake is assistant professor and specialist registrar in Cardiology at the University Medical Center Utrecht and Hubrecht Institute. She carries...

By: UniversiteitUtrecht

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[International version] Linda van Laake: "We want to work together to improve stem cell treatment" - Video

Stem Cell Treatments for Chronic Bronchitis in 2013 |

Overview: What Are Stem Cell Treatments for Chronic Bronchitis?

Stem cell treatments for chronic bronchitis are one of the latest advancements in chronic bronchitis treatments available today, and are being utilized in clinical settings around the world. Once considered an alternative form of treatment for chronic bronchitis and other forms of lung disease, stem cell therapies for chronic bronchitis are becoming increasingly more common as they provide consistent positive results for patients suffering from mild, moderate, and severe forms of chronic bronchitis. Stem cells and other forms of regenerative medicine are helping people improve their quality of life and breathe easier.

Adipose (Fat-Derived) Stem Cell Procedure & Venous (Blood-Derived) Stem Cell Procedure for Chronic Bronchitis

Lung Institute utilizes adult autologous stem cells, derived from the patients own body, for the adipose (fat-derived) stem cell procedure and the venous (blood-derived) stem cell procedure. These stem cells are extracted, isolated, and immediately reintroduced to the affected lung tissue, where they then divide and replicate into healthy cells specialized to that tissue. The use of autologous stem cells in transplantation is considered to be more reliable than stem cells from another individual as there is a much lower probability of rejection. Both adipose stem cells and venous stem cells have shown anti-inflammatory properties beneficial to patients with lung disease.

Adult stem cells have the ability to self-renew indefinitely, meaning they have the capability to divide many times and specialize in the repair of damaged organs while still sustaining the original undifferentiated cell. The adipose procedure is always performed in conjunction with the venous procedure, while the venous procedure may be chosen to be performed on its own depending on the nature of the patients condition and health history.

Lung Institute does not use any type of embryonic or fetal stem cells in their procedures.

Autologous Mesenchymal Stem Cells

During the adipose procedure human mesenchymal stem cells (hMSCs) are extracted from the patients adipose tissue. hMSCs are immune-modulatory and versatile due to their secreted bioactive molecules, giving them anti-inflammatory and regenerative properties. Because of this, these highly specialized cells have the potential orchestrate the complex reparative processes needed to restore diseased lung tissues. Human mesenchymal stem cells are not only utilized in the restoration of damage lung tissue, but are also capable of regenerating into multiple phenotypes, including cells capable of forming bone, cartilage, muscle, marrow, tendon/ligament, adipocytes (adipose tissue) and connective tissue.

As a result of hMSCs intrinsic capability to differentiate into various phenotypes of mature cells while secreting cytokines and natural growth factors at the site of tissue damage, they have significant therapeutic capacity in sufferers of chronic bronchitis.

In the adipose procedure, following the extraction of hMSCs from fat tissue, hematopoetic stem cells are also extracted through the use of an IV. Both types of stem cells are then washed and separated in the lab. They are then immediately inserted into the patients body intravenously once again for the molecular cueing of regenerative pathways in damaged lung tissues.

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Stem Cell Treatments for Chronic Bronchitis in 2013 |

Tackling Huntington’s disease with stem cell therapy in mice

The neurodegenerative disorder Huntingtons disease (HD) is characterised by diminished muscle coordination, cognitive impairment and behavioural changes. It is a genetic disorder caused by the expansion of a CAG trinucleotide repeat in the gene encoding the huntingtin protein. This results in the degeneration of nerve cells, starting with those in the striatum of the brain. At present there is no treatment for this disease, nor any means to slow down its progression. Current therapies therefore focus on managing symptoms. Research is underway to determine whether stem cell therapies could reduce the neuropathological deficits brought on by HD and in doing so slow disease progression. A recent study published in Stem Cell Research & Therapy by Gary Dunbar from Central Michigan University, USA and colleagues, probes the potential of mesenchymal stem cells in treating a mouse model of HD.

Immunohistochemical analysis of low passage (left) and high passage (right) umbilical cord mesenchymal stem cells (blue) transplanted into the striata of R6/2 mice. Stained for NeuN (red) and GFAP (green). Image source: Fink et al, Stem Cell Research & Therapy, 2013, 4:130

Dunbar and colleagues used the R6/2 mouse model of HD to test the efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs). R6/2 mice express the N-terminal portion of the human huntingtin gene, containing a highly expanded CAG repeat, and consequently develop progressive neurological phenotypes resembling the disease in humans. At five weeks of age, R6/2 mice were transplanted with either low passage or high passage UC-MSCs, and were followed for six weeks. The mice underwent a number of behavioural tests, including the rotarod task to assess balance, the Morris water maze and the limb-clasping response. They were subsequently sacrificed for histological analysis. Wild-type and sham-operated R6/2 mice served as the controls.

R6/2 mice treated with high passage UC-MSCs performed better on the rotarod task compared with untreated R6/2 mice at ten weeks of age, although the improvement was transient. The most promising effects of treatment with high passage UC-MSCs were seen in the reduction of neuropathological deficits. The researchers found that untreated R6/2 mice had significantly smaller brain areas than wild-type animals, suggesting brain atrophy. This effect was mitigated in mice treated with high passage UC-MSCs, which showed no difference from wild-type mice in measures of brain area. Transplantation of high passage UC-MSCs into R6/2 mice also preserved substantially more metabolic activity in striatal brain tissue compared with untreated animals.

Although no long-term effects on behaviour were observed in this study, the fact that UC-MSCs significantly reduced neuropathological deficits suggests that stem cells could have therapeutic value in the management of HD.

Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

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Tackling Huntington’s disease with stem cell therapy in mice

Janice Dickinson’s Freak Accident and Stem Cell Healing – Us …

Janice Dickinson is on the mend! "On July 7 I had an accident at Rite Aid," Dickinson, 58, tells Us Weekly. "I was walking out of the parking lot and turned to say something to the parking attendant. As soon as I looked back to where I was walking, the bar knocked me out on top of my head."

PHOTOS: Celebrity health scares

The worlds first supermodel headed to a Los Angeles hospital where she underwent a series of tests, leading to a diagnosis of a concussion "with damage to my neck, shoulder blades, back and knee. Ever since then, my life has been miserable," she explained. While Dickinson had the support of her fianc, Dr. Robert "Rocky" Gerner, whom she calls "my right arm" and "my knight in shining armor," she eventually sought treatment in China with longtime friend, Dr. Brian Mehling, founder of Blue Horizon Stem Cells.

PHOTOS: Supermodels: Then and now

Mehling suggested that Dickinson try a stem cell treatment commonly used in China, where stem cells are harvested in a laboratory and then injected into the patients problem area. "In Janice's case," Mehling tells Us about her September procedure, "they injected some stem cells to the spinal fluids so that it could get into the central nervous system and the other half of the cells were injected through an IV in her hand and that would treat the peripheral problem." Dickinson tells Us, "I was back to my normal self instantaneously! I woke up feeing just energized, jazzed to new levels." The outspoken former Americas Next Top Model judge laments that she still cant wear heels 4-and-a-half-months after her accident, and that she will have to have the treatment again, but is still thrilled with the results.

PHOTOS: Memorable reality TV moments

Impressed by the stem cell technology, she also started using and promoting Blue Horizon Special Skin Serum (which does not actually contain stem cells). "This is absolutely the greatest tonic fountain of youth that I've ever found in my life," Dickinson tells Us. The I'm a CelebrityGet Me Out of Here! alum has been using this serum all over her body to improve her skin. "I had all these scars from a gardening accident and all those little scars on my arms and forearms just disappeared! It's spooky!" Mehling and Dickinson are offering Us Weekly readers a $50 discount on their Blue Horizon Special Skim Serum with the code JaniceLovesUs at their website.

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Bone Marrow Transplantation and Peripheral Blood Stem Cell …

What are bone marrow and hematopoietic stem cells?

Bone marrow is the soft, sponge-like material found inside bones. It contains immature cells known as hematopoietic or blood-forming stem cells. (Hematopoietic stem cells are different from embryonic stem cells. Embryonic stem cells can develop into every type of cell in the body.) Hematopoietic stem cells divide to form more blood-forming stem cells, or they mature into one of three types of blood cells: white blood cells, which fight infection; red blood cells, which carry oxygen; and platelets, which help the blood to clot. Most hematopoietic stem cells are found in the bone marrow, but some cells, called peripheral blood stem cells (PBSCs), are found in the bloodstream. Blood in the umbilical cord also contains hematopoietic stem cells. Cells from any of these sources can be used in transplants.

What are bone marrow transplantation and peripheral blood stem cell transplantation?

Bone marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) are procedures that restore stem cells that have been destroyed by high doses of chemotherapy and/or radiation therapy. There are three types of transplants:

Why are BMT and PBSCT used in cancer treatment?

One reason BMT and PBSCT are used in cancer treatment is to make it possible for patients to receive very high doses of chemotherapy and/or radiation therapy. To understand more about why BMT and PBSCT are used, it is helpful to understand how chemotherapy and radiation therapy work.

Chemotherapy and radiation therapy generally affect cells that divide rapidly. They are used to treat cancer because cancer cells divide more often than most healthy cells. However, because bone marrow cells also divide frequently, high-dose treatments can severely damage or destroy the patients bone marrow. Without healthy bone marrow, the patient is no longer able to make the blood cells needed to carry oxygen, fight infection, and prevent bleeding. BMT and PBSCT replace stem cells destroyed by treatment. The healthy, transplanted stem cells can restore the bone marrows ability to produce the blood cells the patient needs.

In some types of leukemia, the graft-versus-tumor (GVT) effect that occurs after allogeneic BMT and PBSCT is crucial to the effectiveness of the treatment. GVT occurs when white blood cells from the donor (the graft) identify the cancer cells that remain in the patients body after the chemotherapy and/or radiation therapy (the tumor) as foreign and attack them. (A potential complication of allogeneic transplants called graft-versus-host disease is discussed in Questions 5 and 14.)

What types of cancer are treated with BMT and PBSCT?

BMT and PBSCT are most commonly used in the treatment of leukemia and lymphoma. They are most effective when the leukemia or lymphoma is in remission (the signs and symptoms of cancer have disappeared). BMT and PBSCT are also used to treat other cancers such as neuroblastoma (cancer that arises in immature nerve cells and affects mostly infants and children) and multiple myeloma. Researchers are evaluating BMT and PBSCT in clinical trials (research studies) for the treatment of various types of cancer.

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Stem Cell Therapy Research Dr. Steenblock Umbilical Cord Stem …

We stand at the threshold of a new and exciting medicine of Regeneration where transplants of stem cells can potentially restore function to injured, diseased and debilitated tissues and organs.

Embryonic-like stem cells found in umbilical cord blood!

Umbilical cord blood was first used for blood and immune system disorders about 18 years ago.For the past several years, new possibilities for their use in a wider variety of health conditions, genetic disorders and anti-aging treatmentshave beengaining support with various multipotent stem cells and progenitor cells being discovered in the cord blood. In fact, embryonic-like stem cells have actually been found in umbilical cord blood and are beingused in clinical researchnow for various neurological disorders outside the United States. Dr. Colin McGuckin and associates from the U.K. have published preliminary findings on these embryonic-like stem cells.

Whether the health challenge is Alzheimer's Disease, Stroke, Traumatic Brain Injury, Cerebral Palsy, Spinal Cord Injuries, Parkinson's Disease, Heart Disease, Diabetes, Blindness or Immune Deficiencies, the results of preliminary animal and human studies have been very promising.

With each passing year, the field is growing exponentially and we invite you to find out more about this exciting new field of regenerative medicine.

This website is sponsored by the Steenblock Research Institute, a 501(c)(3)California non-profit corporation dedicated to educating the public about safe and effective alternatives for difficult medical cases. Contribute to our on-going projects in researching medical alternatives here.

UMBILICAL CORD STEM CELL THERAPY by David Steenblock, D.O. and Anthony Payne, Ph.D.

This book presents case studies of umbilical cord stem cells being used to treat patients with cancer, cerebral palsy, stroke, ALS, MS and other challenging medical conditions.

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Stem Cell Therapy Research Dr. Steenblock Umbilical Cord Stem ...

Adult Stem Cells – Therapies and Treatments –

Life-Saving Stem Cells - Discover, Learn, ShareNearly everyone inside and outside of the medical and scientific community agrees that stem cell research represents one of the most exciting and promising frontiers for treating people with a myriad of diseases and conditions. Stem cell research and treatments represent perhaps mankind's greatest opportunity to fulfill that ancient call to "heal the sick," relieve suffering and improve the quality of life for untold millions of people.

This website provides scientific facts and concise information for those of us who are not scientists, researchers or medical professionals. You will learn answers toquestions like ..."Who is benefitting from stem cell research and therapies today?" and "What types of stem cells are working?" In addition, basic questions such as"What is a stem cell?""Why do we need stem cell research?" are answered.

The video patient profiles featured on this site emphasize ADULT stem cell advances with the goal of informing and the hope of inspiring you to take action. These real-life stories represent a small sampling of people and the many diseases and conditions now being helped by adult stem cells naturally found in the human body. Stem Cell Research Facts illustrates how current adult treatments and therapies directly impact the lives of patients and their families today - as opposed to debating themerits of other types of stem cell research.

We invite you to discover, learn and share the incredible possibilites of stem cell research. We welcome your feedback and encourage you to return for the latest developments in the world of stem cell research. Thank you!

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Adult Stem Cells - Therapies and Treatments -

Regenerative Medicine Inst – Stem Cell Therapy Mexico Stem …

PUTTING PATIENTS FIRST Regenerative Medicine Instituteis a multispeciality group of Board Certified physicians and allied health professionals working together to meet the needs of patients and families living with chronic degenerative disease. They work to streamline the referral process, share information with other healthcare personnel, communicate and work with primary care physicians and case managers, research treatments and procedures to find the best options for treating the causes of degenerative disease, and participate in drug trials and research.

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History of Stem Cell Treatment | Guidelines to follow when choosing stem cell therapy

Scientists have long been fascinated by the power of stem cells, which has led to current stem cell treatment. These adaptive cells have the potential to develop into different kinds of cells, depending upon what the human body needs them to be. They act as a personal repair system, uniquely able to regenerate damaged tissue. Better yet, stem cells divide without limit, giving the body a fighting chance to fight degeneration. While scientists have long suspected the potential of stem cells in healing, 1973 was the first time physicians were able to successfully perform the first stem cell transplant between unrelated patients. Stem cell therapy has mushroomed since that time as physicians realized that the same stem cells used to fight diseases such as leukemia can also treat Alzheimer's disease, COPD, heart disease and other degenerative conditions.

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Regenerative Medicine Inst - Stem Cell Therapy Mexico Stem ...