Providing CAR T-Cell Therapy for Patients With DLBCL During COVID-19 – Targeted Oncology

Nilanjan Ghosh, MD, discusses the effect coronavirus disease 2019 had on using chimeric antigen receptor T-cell therapy to treat patients with diffuse large B-cell lymphoma.

Nilanjan Ghosh, MD, a hematologist and medical oncologist at the Levine Cancer Institute, Atrium Health, discusses the effect coronavirus disease 2019 (COVID-19) had on using chimeric antigen receptor (CAR) T-cell therapy to treat patients with diffuse large B-cell lymphoma (DLBCL).

Ghosh says that when the pandemic first started, he and other physicians thought it would not only affect CAR T-cell therapy but also stem cell transplants. CAR T-cell treatments for DLBCL include therapies such as axicabtagene ciloleucel (Yescarta) and tisagenlecleucel (Kymriah). There was a lot of uncertainty around how long the pandemic would last since it started abruptly with many acute cases, which filled intensive care units and hospital beds.

As the months went on, physicians adapted to treating patients during COVID-19, which Ghosh calls the new normal. As of October, the pandemic was not affecting the delivery of CAR T-cell therapy for clinical trials and treatment with standard of care in practices. At the beginning of COVID-19, he and his colleagues were doing their best to deliver standard-of-care CAR T therapy, but it did affect CAR T-cell delivery for clinical trials because of regulatory constraints. There were several months where accrual for these trials was limited, but over the past months, many of those constraints have been lifted and the clinical trials have opened back up.

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Providing CAR T-Cell Therapy for Patients With DLBCL During COVID-19 - Targeted Oncology

BioRestorative Therapies Emerges from Chapter 11 Reorganization – OrthoSpineNews

MELVILLE, N.Y., Nov. 20, 2020 (GLOBE NEWSWIRE) BioRestorative Therapies, Inc. (BioRestorative or the Company) (OTC: BRTX), a life sciences company focused on stem cell-based therapies, announced today that its amended joint plan of reorganization has become effective and it has emerged from Chapter 11 reorganization. Pursuant to the confirmed plan of reorganization, the Company has received $3,848,000 in financing. The confirmed plan of reorganization also provides for additional funding, subject to certain conditions, of $3,500,000 less the sum of the debtor-in-possession financing provided to the Company during the reorganization (approximately $1,227,000) and the costs incurred by the debtor-in-possession lender.

In connection with the reorganization, Lance Alstodt has been appointed the Companys President, Chief Executive Officer and Chairman of the Board. Mr. Alstodt said, This process has been a long and challenging journey for the Company. Im inspired by the great resolve and execution from our employees, professionals and investors. We are very pleased that all requirements have been met for us to emerge. Allowed creditor claims have been fully satisfied and, as importantly, our equity holders have retained their shares in this exciting new opportunity. We were able to preserve all of our intellectual property assets and look forward to initiating our Phase 2 clinical trial.

Based upon the Companys emergence from Chapter 11 reorganization, FINRA has removed the Q at the end of its trading symbol. Shareholders do not need to exchange their shares for new shares.

About BioRestorative Therapies, Inc.

BioRestorative Therapies, Inc. (www.biorestorative.com) develops therapeutic products using cell and tissue protocols, primarily involving adult stem cells. Our two core programs, as described below, relate to the treatment of disc/spine disease and metabolic disorders:

Disc/Spine Program (brtxDISC): Our lead cell therapy candidate,BRTX-100,is a product formulated from autologous (or a persons own) cultured mesenchymal stem cells collected from the patients bone marrow. We intend that the product will be used for the non-surgical treatment of painful lumbosacral disc disorders. TheBRTX-100production process utilizes proprietary technology and involves collecting a patients bone marrow, isolating and culturing stem cells from the bone marrow and cryopreserving the cells. In an outpatient procedure,BRTX-100is to be injected by a physician into the patients damaged disc. The treatment is intended for patients whose pain has not been alleviated by non-invasive procedures and who potentially face the prospect of surgery. We have received authorization from the Food and Drug Administration to commence a Phase 2 clinical trial usingBRTX-100to treat persistent lower back pain due to painful degenerative discs.

Metabolic Program (ThermoStem): We are developing a cell-based therapy to target obesity and metabolic disorders using brown adipose (fat) derived stem cells to generate brown adipose tissue (BAT). BAT is intended to mimic naturally occurring brown adipose depots that regulate metabolic homeostasis in humans. Initial preclinical research indicates that increased amounts of brown fat in the body may be responsible for additional caloric burning as well as reduced glucose and lipid levels. Researchers have found that people with higher levels of brown fat may have a reduced risk for obesity and diabetes.

Forward-Looking Statements

This press release containsforward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events or results to differ materially from those projected in the forward-looking statements as a result of various factors and other risks, including, without limitation, those set forth in the Companys latest Form 10-K filedwith the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and the Company undertakes no obligation to update such statements.

CONTACT: Email: ir@biorestorative.com

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BioRestorative Therapies Emerges from Chapter 11 Reorganization - OrthoSpineNews

Stem Cell Therapy Market 2020 Trends, Market Share, Industry Size, Growth, Sales, Opportunities, Analysis and Forecast To 2026 – The Daily…

This newly added research report presentation on global Stem Cell Therapy market unwinds with a crisp market definitions, overview and executive summary that allow report readers to dwell into crucial milestones pertaining to market segmentation, classification as well as technological overview and product portfolio advances that shape vendor preferences and activities, cost structure as well as overall gross margin of the market and industrial landscape.

The report significantly focuses over other details such as COVID-19 impact that have vitally influenced and catalyzed growth curve in global Stem Cell Therapy market.

Get PDF Sample Report of Stem Cell Therapy (COVID-19 Version) Market 2020, Click Here @ https://www.adroitmarketresearch.com/contacts/request-sample/691?utm_source=Pallavi

Scope of the Report

This aforesaid Stem Cell Therapy market has noted a growth estimate of xx million US dollars in 2020 and is also likely to show favorable growth worth xx million US dollars through the forecast tenancy until 2025, clocking at an robust CAGR of xx% through the forecast period, 2020-25.

The report has included significant details about various facets covering manufacturer activities to offset the challenges prevalent during COVID-19.

The report in the following sections, emphasizes details on various market players, stakeholders, and participants. Details on upstream and downstream developments, production and consumption patterns are also addressed in the report to influence holistic and balanced growth in the global Stem Cell Therapy market.

Segment-based Analysis: Global Stem Cell Therapy Market

To arrive at highly reliable, unbiased and logical deductions involving developments in global Stem Cell Therapy market, the report has been articulated across decisive information aligning with primary and secondary research practices to meet international standards of data gathering. Exclusive report contents suggest that the global Stem Cell Therapy market is effectively diversified into broad segments and categories encompassing type and application besides regional diversification.

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Stem Cell Therapy Market Segmentation

Type Analysis of Stem Cell Therapy Market:

Based on cell source, the market has been segmented into,

Adipose Tissue-Derived Mesenchymal SCs Bone Marrow-Derived Mesenchymal SCs Embryonic SCs Other Sources

Applications Analysis of Stem Cell Therapy Market:

Based on therapeutic application, the market has been segmented into,

Musculoskeletal Disorders Wounds & Injuries Cardiovascular Diseases Gastrointestinal Diseases Immune System Diseases Other Applications

Assessing Prominent Catalysts: Global Stem Cell Therapy Market

Driver Analysis: The report includes a lucid reference of the noteworthy factors that collectively steer high investment returns and market stability in global Stem Cell Therapy market. Barrier Assessment: The report in its subsequent sections broadly isolates the major deterrents and growth retarding factors that have remained crucial in growth regression, compounded by unprecedented pandemic outrage. Opportunity Identification: This Stem Cell Therapy market relevant report is a highly dependable information source to unravel new growth scope and untapped market opportunities. Information cited in this report section is likely to influence novel M&A mergers, collaborations as well as geographic and facility expansion programs to ensure optimistic returns.

Unraveling Competitive Landscape:

The report critically examines the competition diaspora, flagging frontline players as well as other notable key competitors likely to defend a crucial lead in global Stem Cell Therapy market despite soaring competition as well as fast changing dynamics.

Each of the mentioned profiles in the report has been thoroughly assessed and details on their company overview, business objectives and planning as well as SWOT review of the companies have been primarily focused in this report to ensure superlative reader comprehension and subsequent growth intensive business decisions and adequate competitive edge.

What to Expect from the Report

The report presents a detailed chapter on industry segmentation, proceeding further with sub-segments Holistic review and a thorough industry-based segmentation has also been provided for the growth span, 2020-25 The report clearly assigns a specifically dedicated section on evaluation of various industry challenges, threats, and pertinent growth barriers The report also lays focus on the threat probability of product substitutes and their potential towards growth prognosis.

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Stem Cell Therapy Market 2020 Trends, Market Share, Industry Size, Growth, Sales, Opportunities, Analysis and Forecast To 2026 - The Daily...

Animal Stem Cell Therapy Market 2020 Impact of COVID-19 | Size, Share & Latest Trends, Analysis Report by Manufacturers, Application, Type and…

Animal Stem Cell Therapy Market 2020 this report is including with the COVID19 Outbreak Impact analysis of key points influencing the growth of the market. Report provides a basic overview of the industry including definitions, classifications, applications and chain structure. The Animal Stem Cell Therapy market analysis is provided for the international markets including Development trends, competitive landscape analysis, and key regions development status. The Global Animal Stem Cell Therapy Market report focuses on global major leading industry players providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out. It presents the 360-degree overview of the competitive landscape of the industries. Animal Stem Cell Therapy Market is showing steady growth and CAGR is expected to improve during the forecast period.

Prominent Players Profiled in the Report are MediVet Biologic VETSTEM BIOPHARMA J-ARM Celavet Magellan Stem Cells U.S. Stem Cell Cells Power Japan ANIMAL CELL THERAPIES Animal Care Stem Cell Therapy Sciences VetCell Therapeutics Animacel Aratana Therapeutics

Based on the type of product, the global Animal Stem Cell Therapy market segmented into Veterinary Hospitals Horses Others

Based on the end-use, the global Animal Stem Cell Therapy market classified into Veterinary Hospitals Research Organizations

The research study concisely dissects the Animal Stem Cell Therapy Market and unearths valuable estimations pertaining to the profit projections, market size, sales capacity, and numerous other crucial parameters. Also, the Animal Stem Cell Therapy Market report appraises the industry fragments as well as the driving factors impacting the remuneration scale of this industry.

A Free report data (as a form of Excel Datasheet) will also be provided upon request along with a new purchase.

Animal Stem Cell Therapy Market Region Coverage (Regional Production, Demand & Forecast by Countries etc.):

Overview of the chapters analysing the global Animal Stem Cell Therapy Market in detail:

Chapter 1 details the information relating to Animal Stem Cell Therapy introduction, Scope of the product, market overview, Market risks, driving forces of the market, etc

Chapter 2 analyses the top manufacturers of the Animal Stem Cell Therapy Market by sales, revenue etc for the Forecast period 2020 to 2025

Chapter 3 analyze on the competition landscape amongst the top manufacturers based on sales, revenue, market share etc for the period 2020 to 2025.

Chapter 4 defines the global Animal Stem Cell Therapy market by regions and their market share, sales, revenue etc for the period 2020 to 2025.

Chapters 5 to 9 analyse the Animal Stem Cell Therapy regions with Animal Stem Cell Therapy countries based on market share, revenue, sales etc.

Chapter 10 and 11 contain the knowledge concerning market basis types and application, sales market share, growth rate etc for forecast period 2020 to 2025.

Chapter 12 focuses on the market forecast for 2020 to 2025 for the Animal Stem Cell Therapy Market by regions, type and application, sales and revenue.

Chapter 13 to 15 contain the transient details associate to sales channels, suppliers, traders, dealers, research findings and conclusion etc for the Animal Stem Cell Therapy Market.

Note In order to provide more accurate market forecast, all our reports will be updated before delivery by considering the impact of COVID-19.

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Animal Stem Cell Therapy Market 2020 Impact of COVID-19 | Size, Share & Latest Trends, Analysis Report by Manufacturers, Application, Type and...

Canine Stem Cell Therapy Market 2020 impact of COVID-19 on Industry Size, Share, Global Analysis, Development Status, Regional Trends, Opportunity…

Global Canine Stem Cell Therapy Market (2020) thoroughly scrutinizes the effects of a wide range of factors impacting the market drivers and development. Furthermore, it offers in-depth insights into the key producers, market outline, as well as conjecture and provincial investigation. This report also inspects the global Canine Stem Cell Therapy market wholesalers, deals channels, difficulties, openings, drivers, future patterns, development rate, market share, rivalry scene, and status. Geographically, this report provides the import, fare, clear utilization, and creation of Canine Stem Cell Therapy in Southeast Asia, Japan, China, Europe, North America and India.

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The global Canine Stem Cell Therapy market is anticipated to rise at a considerable rate during the forecast period, between 2020 and 2026. In 2020, the market was growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

The Global Canine Stem Cell Therapy market 2020 research provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Global Canine Stem Cell Therapy Market Share analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed.

Final Report will add the analysis of the impact of COVID-19 on this industry.

Under COVID-19 Outbreak, how the Canine Stem Cell Therapy Industry will develop is also analyzed in detail in Chapter 1.7 of the report. In Chapter 2.4, we analyzed industry trends in the context of COVID-19 for Canine Stem Cell Therapy Market. In Chapter 3.5, we analyzed the impact of COVID-19 on the product industry chain based on the upstream and downstream markets for Canine Stem Cell Therapy Market. In Chapters 6 to 10 of the report, we analyze the impact of COVID-19 on various regions and major countries on Canine Stem Cell Therapy Market. In chapter 13.5, the impact of COVID-19 on the future development of the industry is pointed out.

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The report can help to understand the market and strategize for business expansion accordingly. In the strategy analysis, it gives insights from marketing channel and market positioning to potential growth strategies, providing in-depth analysis for new entrants or exists competitors in the Canine Stem Cell Therapy industry.This report also states import/export consumption, supply and demand Figures, cost, price, revenue and gross margins. For each manufacturer covered, this report analyzes their Canine Stem Cell Therapy manufacturing sites, capacity, production, ex-factory price, revenue and market share in global market.

Global Canine Stem Cell Therapy Market Report 2020 provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

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List Of TOP KEY PLAYERS in Canine Stem Cell Therapy Market Report are

Get a Sample Copy of the Canine Stem Cell Therapy Market Report 2020

The report also focuses on global major leading industry players of Global Canine Stem Cell Therapy Market Share providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out. With tables and figures helping analyse worldwide Global Canine Stem Cell Therapy Market Forecast this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

The Global Canine Stem Cell Therapy Market Trends, development and marketing channels are analysed. Finally, the feasibility of new investment projects is assessed and overall research conclusions offered.

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On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into

On the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including

Some of the key questions answered in this report:

Major regions covered in the report:

Major Points from Table of Contents:

1 Canine Stem Cell Therapy Introduction and Market Overview 1.1 Objectives of the Study 1.2 Overview of Canine Stem Cell Therapy 1.3 Scope of The Study 1.3.1 Key Market Segments 1.3.2 Players Covered 1.3.3 COVID-19s impact on the Canine Stem Cell Therapy industry 1.4 Methodology of The Study 1.5 Research Data Source

2 Executive Summary 2.1 Market Overview 2.1.1 Global Canine Stem Cell Therapy Market Size, 2015 2020 2.1.2 Global Canine Stem Cell Therapy Market Size by Type, 2015 2020 2.1.3 Global Canine Stem Cell Therapy Market Size by Application, 2015 2020 2.1.4 Global Canine Stem Cell Therapy Market Size by Region, 2015 2025 2.2 Business Environment Analysis 2.2.1 Global COVID-19 Status and Economic Overview 2.2.2 Influence of COVID-19 Outbreak on Canine Stem Cell Therapy Industry Development

3 Industry Chain Analysis 3.1 Upstream Raw Material Suppliers of Canine Stem Cell Therapy Analysis 3.2 Major Players of Canine Stem Cell Therapy 3.3 Canine Stem Cell Therapy Manufacturing Cost Structure Analysis 3.3.1 Production Process Analysis 3.3.2 Manufacturing Cost Structure of Canine Stem Cell Therapy 3.3.3 Labor Cost of Canine Stem Cell Therapy 3.4 Market Distributors of Canine Stem Cell Therapy 3.5 Major Downstream Buyers of Canine Stem Cell Therapy Analysis 3.6 The Impact of Covid-19 From the Perspective of Industry Chain 3.7 Regional Import and Export Controls Will Exist for a Long Time 3.8 Continued downward PMI Spreads Globally

4 Global Canine Stem Cell Therapy Market, by Type 4.1 Global Canine Stem Cell Therapy Value and Market Share by Type (2015-2020) 4.2 Global Canine Stem Cell Therapy Production and Market Share by Type (2015-2020) 4.3 Global Canine Stem Cell Therapy Value and Growth Rate by Type (2015-2020) 4.3.1 Global Canine Stem Cell Therapy Value and Growth Rate of Allogeneic Stem Cells 4.3.2 Global Canine Stem Cell Therapy Value and Growth Rate of Autologous Stem Cells 4.4 Global Canine Stem Cell Therapy Price Analysis by Type (2015-2020)

5 Canine Stem Cell Therapy Market, by Application 5.1 Downstream Market Overview 5.2 Global Canine Stem Cell Therapy Consumption and Market Share by Application (2015-2020) 5.3 Global Canine Stem Cell Therapy Consumption and Growth Rate by Application (2015-2020) 5.3.1 Global Canine Stem Cell Therapy Consumption and Growth Rate of Veterinary Hospitals (2015-2020) 5.3.2 Global Canine Stem Cell Therapy Consumption and Growth Rate of Veterinary Clinics (2015-2020) 5.3.3 Global Canine Stem Cell Therapy Consumption and Growth Rate of Veterinary Research Institutes (2015-2020)

6 Global Canine Stem Cell Therapy Market Analysis by Regions 6.1 Global Canine Stem Cell Therapy Sales, Revenue and Market Share by Regions 6.1.1 Global Canine Stem Cell Therapy Sales by Regions (2015-2020) 6.1.2 Global Canine Stem Cell Therapy Revenue by Regions (2015-2020) 6.2 North America Canine Stem Cell Therapy Sales and Growth Rate (2015-2020) 6.3 Europe Canine Stem Cell Therapy Sales and Growth Rate (2015-2020) 6.4 Asia-Pacific Canine Stem Cell Therapy Sales and Growth Rate (2015-2020) 6.5 Middle East and Africa Canine Stem Cell Therapy Sales and Growth Rate (2015-2020) 6.6 South America Canine Stem Cell Therapy Sales and Growth Rate (2015-2020)

7 North America Canine Stem Cell Therapy Market Analysis by Countries 7.1 The Influence of COVID-19 on North America Market 7.2 North America Canine Stem Cell Therapy Sales, Revenue and Market Share by Countries 7.2.1 North America Canine Stem Cell Therapy Sales by Countries (2015-2020)

Continued

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Canine Stem Cell Therapy Market 2020 impact of COVID-19 on Industry Size, Share, Global Analysis, Development Status, Regional Trends, Opportunity...

Stem Cell Therapy Market, Share, Application Analysis, Regional Outlook, Competitive Strategies & Forecast up to 2026 – The Daily Philadelphian

Stem Cell Therapy Market Overview 2020 2026

This has brought along several changes in This report also covers the impact of COVID-19 on the global market.

The risingtechnology in Stem Cell Therapy Marketis also depicted in thisresearchreport. Factors that are boosting the growth of the market, and giving a positive push to thrive in the global market is explained in detail.

Get a Sample PDF copy of the report @ https://reportsinsights.com/sample/62076

Key Competitors of the Global Stem Cell Therapy Market are: Osiris Therapeutics NuVasive Chiesi Pharmaceuticals JCRPharmaceutical Pharmicell Medi-post Anterogen Molmed Takeda (TiGenix)

Historical data available in the report elaborates on the development of the Stem Cell Therapy on national, regional and international levels. Stem Cell Therapy Market Research Report presents a detailed analysis based on the thorough research of the overall market, particularly on questions that border on the market size, growth scenario, potential opportunities, operation landscape, trend analysis, and competitive analysis.

Major Product Types covered are: Autologous Allogeneic

Major Applications of Stem Cell Therapy covered are: Musculoskeletal Disorder Wounds & Injuries Cornea Cardiovascular Diseases

This study report on global Stem Cell Therapy market throws light on the crucial trends and dynamics impacting the development of the market, including the restraints, drivers, and opportunities.

The fundamental purpose of Stem Cell Therapy Market report is to provide a correct and strategic analysis of the Stem Cell Therapy industry. The report scrutinizes each segment and sub-segments presents before you a 360-degree view of the said market.

Market Scenario:

The report further highlights the development trends in the global Stem Cell Therapy market. Factors that are driving the market growth and fueling its segments are also analyzed in the report. The report also highlights on its applications, types, deployments, components, developments of this market.

Highlights following key factors:

:-Business descriptionA detailed description of the companys operations and business divisions. :-Corporate strategyAnalysts summarization of the companys business strategy. :-SWOT AnalysisA detailed analysis of the companys strengths, weakness, opportunities and threats. :-Company historyProgression of key events associated with the company. :-Major products and servicesA list of major products, services and brands of the company. :-Key competitorsA list of key competitors to the company. :-Important locations and subsidiariesA list and contact details of key locations and subsidiaries of the company. :-Detailed financial ratios for the past five yearsThe latest financial ratios derived from the annual financial statements published by the company with 5 years history.

Our report offers:

Market share assessments for the regional and country level segments. Market share analysis of the top industry players. Strategic recommendations for the new entrants. Market forecasts for a minimum of 9 years of all the mentioned segments, sub segments and the regional markets. Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations). Strategic recommendations in key business segments based on the market estimations. Competitive landscaping mapping the key common trends. Company profiling with detailed strategies, financials, and recent developments. Supply chain trends mapping the latest technological advancements.

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Stem Cell Therapy Market, Share, Application Analysis, Regional Outlook, Competitive Strategies & Forecast up to 2026 - The Daily Philadelphian

gift of life marrow registry announces new center for cell and gene therapy – The Boca Raton Tribune

Chamber Member Update

Boca Raton, FL, November 17 Every three minutes a person in the United States is diagnosed with a blood disease such as leukemia, immunodeficiencies and sickle cell. To deliver cutting-edge, lifesaving therapy services for stem cell transplantations and improve patient outcomes, the Gift of Life Marrow Registry has announced the newly opened the Gift of Life Center for Cell and Gene Therapy.

Located at Gift of Lifesheadquarters in Boca Raton, Fla., theCenter will provide transplant physicians, researchers, and cell and gene therapy developers with the donor cell products they need to help more patients than ever before. One of the Centers signature services will be a biobank of off-the-shelf, on-demand cell therapy products available for transplantation, as well as those for engineering and ethical research. The inventory will be comprised of products collected from super donors with high frequency genetic characteristics sourced from the Gift of Life Marrow Registry. These cells will be tested, processed and cryopreserved by the Centers cellular therapy laboratory.

Another specialty service is the Centers innovation program, which will collaborate with world-renowned South Florida research institutions to improve transplant outcomes, develop processes for cell expansion and much more.

While many advancements have been made in stem cell treatments for those with blood diseases, there are still critical barriers that can impeded success, said Gift of Life CEO and Founder Jay Feinberg.

The only registry in the world started and run by a transplant survivor, Gift of Life has pioneered key innovations in the stem cell transplantation and donation process. Last April, the organization become the first registry to operate an in-house stem cell collection center that has not only helped to bring stem cell donors to collection faster, but also greatly improves the experience for donors. Gift of life is also the first registry to use buccal cheek swabs at recruitment drives instead of blood draws and the first to do mobile registration, including the creation of a smart phone app to register individuals quickly and effectively.

Gift of Lifes overarching mission isto democratize celltherapy and ensure that every patient has an equal opportunity to receive the treatment that can save their lives, said Feinberg. Doing so requires innovation, passion and an entrepreneurial approach to the challenges at hand and we are excited to draw upon our 30 years of expertise as we embark on this next phase of our work.

About Gift of Life Marrow RegistryGift of Life Marrow Registry is a 501(c)(3) nonprofit organization headquartered in Boca Raton, Fla. The organization, established in 1991, is dedicated to saving lives by facilitating bone marrow and blood stem cell transplants for patients with leukemia, lymphoma, and other blood-related diseases. To learn more about Gift of Life Marrow Registry, visitwww.giftoflife.org.

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gift of life marrow registry announces new center for cell and gene therapy - The Boca Raton Tribune

Global Canine Stem Cell Therapy Industry Market Analysis, Key Company Profiles, Types, Applications and Forecast To 2026 – Royal Sutton News

A recent market research report added to repository of Credible Markets is an in-depth analysis of Global Canine Stem Cell Therapy Industry Market. On the basis of historic growth analysis and current scenario of Canine Stem Cell Therapy Industry market place, the report intends to offer actionable insights on global market growth projections. Authenticated data presented in report is based on findings of extensive primary and secondary research. Insights drawn from data serve as excellent tools that facilitate deeper understanding of multiple aspects of global Canine Stem Cell Therapy Industry market. This further helps users with their developmental strategy.

This report examines all the key factors influencing growth of global Canine Stem Cell Therapy Industry market, including demand-supply scenario, pricing structure, profit margins, production and value chain analysis. Regional assessment of global Canine Stem Cell Therapy Industry market unlocks a plethora of untapped opportunities in regional and domestic market places. Detailed company profiling enables users to evaluate company shares analysis, emerging product lines, scope of NPD in new markets, pricing strategies, innovation possibilities and much more.

For Better Understanding, Download FREE Sample Copy of Canine Stem Cell Therapy Industry Market Report @ https://www.crediblemarkets.com/sample-request/canine-stem-cell-therapy-industry-market-214209

Data presented in global Canine Stem Cell Therapy Industry market report allows users to realize their market entry potential and devise fruitful developmental strategies to fulfil their business goals. A report sample can be requested to view the report outline before you actually purchase it.

Key players in the global Canine Stem Cell Therapy market covered in Chapter 12:

MediVet Biologic VetStem Biopharma Stem Cell Vet Regeneus Ltd Okyanos Aratana Therapeutics Cell Therapy Sciences Medrego Magellan Stem Cells

In Chapter 4 and 14.1, on the basis of types, the Canine Stem Cell Therapy market from 2015 to 2025 is primarily split into:

Allogeneic Stem Cells Autologous Stem Cells

In Chapter 5 and 14.2, on the basis of applications, the Canine Stem Cell Therapy market from 2015 to 2025 covers:

Veterinary Hospitals Veterinary Clinics Veterinary Research Institutes

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2026) of the following regions:

United States, Canada, Germany, UK, France, Italy, Spain, Russia, Netherlands, Turkey, Switzerland, Sweden, Poland, Belgium, China, Japan, South Korea, Australia, India, Taiwan, Indonesia, Thailand, Philippines, Malaysia, Brazil, Mexico, Argentina, Columbia, Chile, Saudi Arabia, UAE, Egypt, Nigeria, South Africa and Rest of the World

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Some Points from Table of Content

COVID-19 Outbreak-Global Canine Stem Cell Therapy Industry Industry Market Report-Development Trends, Threats, Opportunities and Competitive Landscape in 2020

Chapter 1 Canine Stem Cell Therapy Industry Introduction and Market Overview

Chapter 2 Executive Summary

Chapter 3 Industry Chain Analysis

Chapter 4 Global Canine Stem Cell Therapy Industry Market, by Type

Chapter 5 Canine Stem Cell Therapy Industry Market, by Application

Chapter 6 Global Canine Stem Cell Therapy Industry Market Analysis by Regions

Chapter 7 North America Canine Stem Cell Therapy Industry Market Analysis by Countries

Chapter 8 Europe Canine Stem Cell Therapy Industry Market Analysis by Countries

Chapter 9 Asia Pacific Canine Stem Cell Therapy Industry Market Analysis by Countries

Chapter 10 Middle East and Africa Canine Stem Cell Therapy Industry Market Analysis by Countries

Chapter 11 South America Canine Stem Cell Therapy Industry Market Analysis by Countries

Chapter 12 Competitive Landscape

Chapter 13 Industry Outlook

Chapter 14 Global Canine Stem Cell Therapy Industry Market Forecast

Chapter 15 New Project Feasibility Analyses

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Points Covered in the Report

The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.

The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analysed 12 years data history and forecast.

The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.

Data and information by market player, by region, by type, by application and etc., and custom research can be added according to specific requirements.

The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Impact of Covid-19 in Canine Stem Cell Therapy Industry Market: Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost every country around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Canine Stem Cell Therapy Industry market in 2020. The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor/outdoor events restricted; over forty countries state of emergency declared; massive slowing of the supply chain; stock market volatility; falling business confidence, growing panic among the population, and uncertainty about future.

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Global Canine Stem Cell Therapy Industry Market Analysis, Key Company Profiles, Types, Applications and Forecast To 2026 - Royal Sutton News

Increasing Progenitor Cell Proliferation in the Sub-Ventricular Zone: A Therapeutic Treatment for Progressive Multiple Sclerosis? – DocWire News

Recent Pat Drug Deliv Formul. 2020 Nov 17. doi: 10.2174/1872211314999201117130123. Online ahead of print.

ABSTRACT

INTRODUCTION: The purpose of this study was to determine if pharmacological treatment could increase progenitor cell proliferation in the Sub-ventricular Zone of aged rats. Previous work had shown that increasing progenitor cell proliferation in this region correlated well (R2=0.78; p= 0.0007) with functional recovery in a damaged corpus callosum (white matter tract), suggesting that progenitor cell proliferation results in oligodendrocytes in this region.

METHODS: 10 month old male and female Sprague Dawley rats were fed the drugs for 30 days in cookie dough, then immunocytochemistry was performed on coronal brain sections, using Ki67 labeling to determine progenitor cell proliferation.

RESULTS: Female rats showed low endogenous (control) progenitor cell proliferation, significantly different from male rats (P<0.0001), at this age. Ascorbic Acid (20 mg/kg, daily for 30 days) increased progenitor cell proliferation overall, but maintained the innate gender difference in stem cell proliferation (P=0.001). Prozac (5 mg/kg, daily for 30 days) increased progenitor cell proliferation for females but decreased stem cell proliferation for males, again showing a gender difference (P<0.0001). Simvastatin (1 mg/kg for 30 days) also increased progenitor cell proliferation in females and decreased progenitor cell proliferation in males, leading to a significant gender difference.

DISCUSSION: The three drug combination (fluoxetine, simvastatin, and ascorbic acid, patent # 9,254,281) led to ~ 4 fold increase in progenitor cell proliferation in females, while male progenitor cell proliferation was highest with 50 mg/kg ascorbic acid. However, the ascorbic acid increase in proliferation appears to be only on the sides of the ventricles, which is not the region that normally gives rise to oligodendrocytes.

CONCLUSION: There are innate gender differences in progenitor cell proliferation at the Sub-Ventricular Zone at middle age in rats, possibly due to loss of estrogen in females. We also see notable gender differences in progenitor cell proliferation in the Sub ventricular Zone in the response to common drugs, such as fluoxetine, simvastatin and Vitamin C (ascorbic acid).

PMID:33208084 | DOI:10.2174/1872211314999201117130123

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Increasing Progenitor Cell Proliferation in the Sub-Ventricular Zone: A Therapeutic Treatment for Progressive Multiple Sclerosis? - DocWire News

Glycostem initiates phase I/IIa (pivotal) trial to evaluate the safety and efficacy of oNKord in patients with Acute Myeloid Leukemia (AML) -…

OSS, Netherlands, Nov. 20, 2020 /PRNewswire/ -- Glycostem Therapeutics B.V., a leading clinical-stage company focused on the development of therapeutic off-the-shelf Natural Killer (NK) cells, today announced the opening of a phase I/IIa trial for its lead product oNKord for the treatment of AML patients. The WiNK trial will enroll 33 AML patients at eight clinical sites based in five European countries. oNKord is the company's first-generation off-the-shelf allogeneic NK cellular immunotherapy product. Glycostem is furthermore developing a range of second (CAR-NK) and third generation (TCR-NK) NK products in-house.

"During our phase Isafety study, in which ten elderly AML patients were treated, we verified our lead productoNKordto be a safe therapeutic agent in the field of cellular immunotherapy. Interestingly, year 1 survival data showed promising efficacy outcome (80%) compared to historical cohort data (40%)," tells Troels Jordansen, CEO at Glycostem. "The opening of this phase I/IIa / pivotal trial is an important step and we are looking forward to the data from this study, which will allow us to draw conclusions regarding oNKord safety and tolerability and most importantly its efficacy for treatment of AML patients."

Professor Doctor Arnold Ganser, MD of Hannover Medical School in Germany and WiNK trial coordinating investigator said: "The preliminary efficacy data obtained with oNKord was very promising and NK-cells have proven to be highly capable of targeting cancer cells. Therefore, I am excited about participating and being able to enroll patients in the WiNK trial." He continues: "Currently there is a risk of relapse for 80% of the successfully treated patients. This new form of cellular treatment can change the lives and future prospects of many patients with AML worldwide who do not proceed to allogeneic hematopoietic stem cell transplantation, in particular elderly patients, who represent the majority of patients with AML."

WiNK is a prospective two-stage, open-label, single arm, multicenter phase I/IIa trial to evaluate the safety and efficacy of oNKord, an off-the-shelf, ex. vivo-cultured allogeneic NK cell preparation, in 33 adults with AML who are in complete morphologic remission with residual measurable disease and with no strong indication for hematopoietic stem cell transplantation.

A full description of the WiNK trialis published on http://www.clinicaltrial.gov.

About Glycostem

Netherlands-based Glycostem Therapeutics B.V., a clinical stage biotech company, develops allogeneic cellular immunotherapy to treat several types of cancer. By harnessing the power of stem cell-derived Natural Killer (NK) cells, Glycostem's products are a safer alternative to CAR-T-cells. Glycostem's lead product, oNKord, is manufactured from allogeneic raw material and is available off-the shelf. Thanks to its nine patent families, longstanding technical expertise and resources, as well as 'Orphan Drug Designation', Glycostem has secured a leadership position in the global NK-cell market.

oNKord is produced in a closed system in Glycostem's state-of-the-art and GMP (Good Manufacturing Practice) licensed production facility in the Netherlands, from which it can be distributed globally. The production technology includes ex vivo generation of high numbers of NK cells with a high degree of purity for clinical applications. oNKord successfully passed phase I clinical trial (elderly and frail AML patients), providing solid safety data and strong indication of clinical activity, including response on MRD (Minimal Residual Disease). Results indicate that oNKord may be safely infused in AML patients.

Glycostem is furthermore developing a range of CAR-NK and TCR-NK products in-house and in cooperation with global partners.

Contacts:

Glycostem Therapeutics BV Troels Jordansen Tel +31 6 1834 5326 [emailprotected] http://www.Glycostem.com

SOURCE Glycostem Therapeutics

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Glycostem initiates phase I/IIa (pivotal) trial to evaluate the safety and efficacy of oNKord in patients with Acute Myeloid Leukemia (AML) -...