Stem Cell Clinic

Canadians More Than Ever are Seeking Cosmetic Procedures of All Types to Look and Feel Best – Press Release – Digital Journal

By Platelet Rich Plasma Injections

In Canada in the past few years, there is a widespread interest in cosmetic procedures, especially the less invasive ones. The less invasive procedures can make phenomenal differences in how a person looks and feels. Because technology is now advanced and the procedures more available and therefore more affordable, more Canadians, are taking the leap towards cosmetic enhancements. Some of the most popular treatments include Botox injections for wrinkle reductions especially around the eye area and forehead. Botox is otherwise known as botulinum toxin and can freeze the facial muscles causing patients to refrain from overuse of some facial muscles.

Dermal and lip fillers are also at the top of the list, and collagen is primarily used for these procedures

Other popular procedures with minimal downtime for recovery are CoolSculpting also known as cryolipolysis, hair loss and hair growth treatments, hair removal treatments, and acne, scar and skin discoloration treatments. CoolSculpting freezes fat cells before removal and is especially popular for those individuals that are seeking to reduce a double chin. Its sometimes referred to as a cool mini as it is also used on other smaller body areas.

No matter what the bodily concern, the new techniques can assist almost anyone

Canada MedLaser Mississauga provides almost all the newest in cosmetic minor enhancements. Hair removal is extremely popular as unwanted hair is killed painlessly at the root using lasers. Those that are suffering from hair loss and thinning hair can benefit from a new technique called Platelet Rich Plasma or PRP, which is also offered at the Mississauga location of CML. Platelet Rich Plasma is taken from ones own body and then injected into the scalp, increasing the chances of new hair growth. It is revolutionary and incredibly non-invasive and has helped individuals with thinning or lost hair who have tried other procedures unsuccessfully. This type of plasma is also called autologous conditioned plasma and is now being used for a wide variety of cosmetic and other medical procedures. It is a new method but seems successful for a variety of conditions both cosmetic and otherwise.

Other cutting-edge plastic surgery techniques can now offer relief from acne scarring and Rosacea

Canada MedLaser Mississauga is versed ina large variety of techniques even Microdermabrasion. In addition, spider vein removal is offered and although an older procedure, this procedure remains very popular. Mississauga CML embraces the new technologies and cosmetic procedures and Canadians can benefit now from the advancement in procedures. From Botox injections to dermal and lip fillers, anti-wrinkle injections, all types of hair removal procedures, and hair thinning and loss as well as hair regrowth treatments, these procedures remain the most popular treatments in Canada today.

About Canada MedLaser Mississauga

This cosmetic clinic is in the Mississauga, Ontario region and specializes in cutting-edge technologies for cosmetic procedures. Botox injections for wrinkle reduction, dermal fillers and lip fillers, hair loss treatments, and hair regrowth treatments are offered alongside such procedures as CoolSculpting. Acne and scar removal as well as other skin conditions can be treated also. There is an online form, email and phone, with free consultations offered. Hours are geared towards the hectic schedule of consumers also and the staff is friendly and well-trained. There is a blog that focuses on explaining the new types of treatments.

Media ContactCompany Name: Canada MedLaser MississaugaContact Person: Media RelationsEmail: Send EmailPhone: 647-494-7764Address:1705 Lakeshore Road City: West MississaugaState: Ontario, L5J 1J4Country: CanadaWebsite: https://canadamedlaser.ca/location/

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Canadians More Than Ever are Seeking Cosmetic Procedures of All Types to Look and Feel Best - Press Release - Digital Journal

Stem Cells Market is expected to reach US$270.5 billion by 2025, TMR – BioSpace

By Adult Stem Cells

The global stem cells market is predicted to witness players seeking funds from international organizations for developing new therapies. With a view to cement their position in the market, players could take to the adoption of partnerships and collaborations with pharmas. This could also help them to expand their product portfolios. While these factors are expected to enhance market growth, there could be a few others helping with strong demand for stem cells.

Transparency Market Research (TMR) foresees the global stem cells market to earn a US$270.5 bn by the completion of 2025 while registering a 13.8% CAGR for the forecast tenure 2017-2025. In a research led by University of Singapores (NUS) Professor G.V. Shivashankar and the FIRC Institute of Molecular Oncology (IFOM), it has been found that mature cells can be confined to reprogram them into re-deployable stem cells. Interestingly, this could be achieved without direct genetic modification.

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Induced Pluripotent Stem Cells as Emerging Segment of Market

There are various types of products available in the global stem cells market: induced pluripotent, human embryonic, and adult stem cells. Among these, the market could find adult stem cells collecting a larger share in the coming years. Their demand could increase due to their potential to multiply into trillions of specialized cells capable of repairing tissue damage and lowering the risk of rejection.

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North America Banks on Massive Investments to Lead Market

On the regional front, the global stem cells market is prognosticated to find North America taking a leading position in the near future. By the end of the forecast period, the region could earn US$167.3 bn. The following factors are anticipated to augur well for the regional market.

North America could be trailed by Europe during the course of the forecast period. Medical tourism in European countries such as Germany could push the growth of the market in the region. Germany welcomes patients from the U.S., Canada, and even other countries. On the other hand Asia Pacific is expected to grow at a faster CAGR of 14.6%.

Some of the key players operating in the global stem cells market are STEMCELL Technologies Inc., Astellas Pharma Inc., Cellular Engineering Technologies Inc., BioTime Inc., Takara Bio Inc., U.S. Stem Cell, Inc., BrainStorm Cell Therapeutics Inc., Cytori Therapeutics, Inc., Osiris Therapeutics, Inc., and Caladrius Biosciences, Inc.

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Stem Cells Market is expected to reach US$270.5 billion by 2025, TMR - BioSpace

New sickle cell disease treatments are helping people live longer and giving them a higher quality of life – PhillyVoice.com

By Adult Stem Cells

Treatment for sickle cell disease has come a long way since the 1970s when the life expectancy of people living with it was less than 20 years.

People with sickle cell disease are not only living longer life expectancy is now 42 to 47 years of age but are enjoying a better quality of life, too.

"In the Philadelphia area, there has been great pediatric care for sickle cells disease and because of that people who have it are living very well," said Dr. Farzana Sayani, a hematologist at Penn Medicine.

Sayani is the director of a comprehensive sickle cell program focusing on adults living with the disease. Penn also has an active transition program for youth transitioning from a pediatric institution to adult care.

Sickle cell disease is an inherited red blood cell disorder that affects about 100,000 Americans.It is most often found in people of African or Hispanic descent.About 1 in 365 African-American babies are born with sickle cell disease, according to Sayani.

People who have the disease inherit an abnormal type of hemoglobin in their red blood cells, called Hemoglobin S, from both their mother and father.When only one parent has the hemoglobin S gene, a child will have the sickle cell trait, but usually does not develop the disease. But they may pass it on to their children.

Hemoglobin is the protein in the blood responsible for carrying oxygen to the rest of the body. Hemoglobin S causes red blood cells to become stiff and sickle-shaped. Instead of being round in shape, they look like crescent moons.

Sickle cells are sticky and can bind together, blocking the flow of blood and preventing oxygen from getting where it needs to go in the body. This causes sudden attacks of pain referred to as a pain crisis.

There are severaldifferent types of sickle cell disease.Hemoglobin SS, also known as sickle cell anemia, is the most common and most severe type of sickle cell disease.

Anemia occurs when red blood cells die at a rate faster than the body can replace them. Normal red blood cells generally live for 90 to 120 days. Sickled cells only live for 10 to 20 days. This shorter life-to-death cycle is harder for the body to sustain.

Another form,Hemoglobin SC, is not as severe as sickle cell anemia, but it can still cause significant complications, Sayani said.Other forms include Hemoglobin S0 thalassemia, Hemoglobin S+ thalassemia, Hemoglobin SD and Hemoglobin SE.

Sickle cell disease screening is a mandatory part of newborn screenings in Pennsylvania.

If the screening is positive, the family is informed and plugged into the health care system in order to receive the proper care.

If the disease is not diagnosed at birth, a blood test can confirm it at any age in which symptoms start to surface.

The severity of sickle cell disease can vary.

Each individual is affected differently, making it difficult to predict who will get what complications, Sayani said. That is why a comprehensive sickle cell program is so important.

Early signs include a yellowish tint to the skin or jaundice, fatigue and a painful swelling of the hands and feet.

"Young children with sickle cell disease may be tired, not eat very well and have delayed growth," Sayani said. "They may also develop anemia, be at greater risk of infection and start to experience pain crises."

Acute pain crises, also known as vaso-occlusive crises, can lead to long stays in the hospital to manage the crippling pain. Children with sickle cell disease also tend to experience delayed growth and puberty.

As a person with sickle cell disease grows older, the sickled red blood cells start to affect various organs, bones and joints.

This can lead to acute chest syndrome, which occurs when damaged lung tissues makes it difficult to breathe. Brain complications, including stroke, are possible.People with sickle cell disease are also prone to heart damage, eye problems, and infections like chlamydia, salmonella and staphylococcus. Chronic and acute pain is common.

There are different types of medicine that can help manage sickle cell disease.

Last year, an oral medicine was approved that makes sickle cells less likely to sickle. So was an intravenous medicine that has been shown to reduce pain crises and hospitalizations by 50%. Some people living with sickle cell disease also may need regular blood transfusions.

Hydroxyurea has also been used successfully for many years to reduce pain crises and the need for blood transfusions and hospitalizations.

Currently, blood and bone marrow transplant is the only way to cure the disease. But it is not an option for everyone because of the difficulty of finding a well-matched stem cell donor.

A related donor is best but only about a third of sickle cell patients have a donor that is related and fully-matched, Sayani said.

While these transplants have a 85% or more success rate, they also are associated with significant risks, including organ dysfunction, infection and graft vs. host disease which can be quite debilitating.

Transplants completed in children have the best results, Sayani said. But because of the risks involved, doctors only suggest it for patients with severe forms of the disease.

Early clinical trials with gene therapy are also showing promise, she added.

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New sickle cell disease treatments are helping people live longer and giving them a higher quality of life - PhillyVoice.com

Olive Oil Consumption Could Lead to a ‘Younger Brain’ in the Elderly, Researchers Say – Olive Oil Times

By Adult Stem Cells

As people age, the more their brains could benefit from the action of an important component in olive oil.

New research has revealed the deeper effects of hydroxytyrosol (HTyr): Not only does it protect brain functions from aging, but it may even restore the vitality of brain neurons, and multiply them.

Italian scientists at the National Research Center (CNR) investigated how hydroxytyrosol works in those portions of the brain that generate new neurons throughout life. They discovered that HTyr impacts brain activities far beyond its well-known neuroprotective effects.

Researchers at the CNR Biochemistry and Cellular biology Lab (CNR-Ibbc) were able to show how the administration of the compound in the elderly may reverse neuronal aging, combining the protection of the active neurons and the generation of new ones.

Hydroxytyrosol oral consumption by young and older animals within amonth shows not only how the new neurons generated by the brain in that timeframe are protected, but it also hints how in older animals it stimulates the multiplication of stem cells, said Felice Tirone, chief scientist and author of the study published in Faseb Journal. It is from those cells that new neurons are generated.

Tirone and his colleagues explained that HTyr activates neurogenesis in the dentate gyrus of an adult, where new neurons are generated, by increasing survival of new neurons and decreasing apoptosis. The neurons multiplication effect is only found in aged brains.

We also found how the antioxidant activity of hydroxytyrosol activates asort of cleaning treatment for nervous cells, in the sense that it washes away several byproducts of brain aging like the lipofuscin, which are debris found in neuron cells, Tirone explained.

The whole array of these effects hints at the possibility of reversing some of the most known effects of brain aging.

Olive oil is at the core of the Mediterranean diet and, as often reported in these pages, its regular consumption has been scientifically linked to health improvements in humans of any age at every latitude.

The new research hints at anew series of products that could help to relieve the reduction of cognitive abilities in aging humans.

CNR scientists underlined in apress statement that hydroxytyrosol is not only found in olive oils people usually consume but also in the byproducts of olive oil production.

That process impacts on the environment, but the biological waste it produces holds great quantities of hydroxytyrosol. By upgrading procedures and means, by splitting the good compounds from the other byproducts, oil mills could obtain hydroxytyrosol while also reducing the environmental impact of their activities, said Tirone.

The CNR statement explained that scientists could verify how the new neurons produced in the brain of the aged individuals actually enter the neuronal circuits and fuel neuronal functionality.

The daily intake of the compound in our study is similar to the dose ahuman could ingest with an enriched diet or food integrators. Still, the most efficient intake of hydroxytyrosol would happen through olive oil consumption, said Laura Micheli, one of the CNR-Ibbc researchers who signed the study.

Scientists also explained that future research will have to verify the behavioral effects of the increased neuron production and the extent of the HTyr treatment of neural aging.

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Olive Oil Consumption Could Lead to a 'Younger Brain' in the Elderly, Researchers Say - Olive Oil Times

Proteostasis Therapeutics and CF Europe Announce Completion of Patient Enrollment for CHOICES, the First-Ever Personalized Medicine-Based Study in…

By Adult Stem Cells

Ex Vivo Testing Phase Underway with Tissue Samples Collected from More than 500 Adult CF Patients; Enrollment Target Exceeded

Clinical Testing Phase to Begin in 2H 2020

Company Expects CHOICES to Potentially Serve as the Basis for an MAA in 2021

BOSTON, Feb. 24, 2020 /PRNewswire/ --Proteostasis Therapeutics, Inc. (NASDAQ:PTI), a clinical stage biopharmaceutical company dedicated to the discovery and development of groundbreaking therapies to treat cystic fibrosis (CF) and CF Europe, the federation of 48 national CF Associations in Europe, today announced the completion of enrollment of 502 patients with CF for HIT-CF, a European-based initiative that is paving the path to personalized medicine through the CHOICES clinical trial. CHOICES will test PTI drug combinations in an ex vivo study and then in a clinical trial to assess the predictability of the organoid assay for clinical benefit.

For the ex vivo portion, organoids derived from tissue samples provided by patients enrolled in the study are evaluated for responsiveness to investigational CFTR modulators, including Proteostasis' CFTR potentiator, corrector and amplifier, dirocaftor (DIR), posenacaftor (POS) and nesolicaftor (NES), respectively. Based on an individual's organoid response, patients will be invited to progress to the next portion of the study which is a placebo controlled, double blind, crossover study known as the CHOICES trial (Crossover trial based on Human Organoid Individual response in CF - Efficacy Study).

The results from CHOICES may serve as the basis for a potential Marketing Authorization Application with the European Medicines Agency (EMA) in 2021 through a novel regulatory pathway. This strategic initiative is led by the HIT-CF consortium, funded through the European Commission's Horizon 2020 program. The CHOICES clinical study is part of PTI's broader clinical development strategy for its CFTR modulator candidates that also includes the MORE trial in CF subjects with the most common F508del homozygous genotype.

"The enrollment of more than 500 patients across Europe in the first phase of the HIT-CF project is a testament to the strategic imperative this program holds for both the patient and treatment community," said Geoffrey Gilmartin, M.D., M.M.Sc., Chief Medical Officer of Proteostasis Therapeutics. "With the successful translation of activity from organoids to patients, this study has the potential to usher in a personalized medicine approach to CF. This approach would begin with patients who have less common mutations, but could ultimately serve the broader CF community by delivering personalized treatment choices that maximize benefit based on each patient's responsiveness to therapy."

"We are excited that Proteostasis is participating in the HIT-CF project and supporting our efforts to bring CF treatment to more people across Europe," said Jacquelien Noordhoek, President of CF Europe and representative of the Netherlands Cystic Fibrosis Society (NCFS). "Enrolled individuals are a portion of the approximately 2,300 adults in the European patient registry who are not eligible for any currently approved modulator due to their genotype and the HIT-CF project represents the only option to explore potential benefit of disease modifying drugs for this group. Putting patients with CF first is our highest priority. We are looking forward to continuing our partnerships and providing Europeans with CF the best possible care."

About Organoids

Organoids are cell cultures that grow in a culture dish with properties similar to those of the organ from which they are derived. Because organoids are made from stem cells, they contain the same mutations as the person from whom the biopsies are derived. Investigational drugs which target the basic defect of CF can be used in an organoid system to evaluate rare mutations where the drugs may have a positive effect.

Unlikein vitrosystems such as human bronchial epithelial (HBE) cells, which are derived from lungs that have been removed from CF patients, or the engineered rat-derived FRT cell line (which has had false positive clinical results), rectal organoids are cultured from tissues obtained through a minimally invasive and painless procedure from donors who then become eligible to participate in a clinical study. Organoids can provide valuable insights for donors, including their likelihood of achieving improvements in pulmonary function and reductions in sweat chloride concentration with CFTR modulators based on theex vivoresponse to those drugsi.

Story continues

About HIT-CF Europe

HIT-CF Europe is a research project which aims to provide better treatment and better lives for people with cystic fibrosis (CF) and rare mutations. To achieve this, drug candidates are first tested on patient-derived organoids in qualified laboratories acrossEurope. Subsequently, based on the measured signal in the organoids, a smaller group of patients will be invited to participate in clinical trials with investigational molecules from participating pharmaceutical companies.

All participating centers are part of theEuropean Cystic Fibrosis Society Clinical Trial Network (ECFS-CTN). The project has received funding from theEuropean Union'sHorizon 2020 research and innovation program under grant agreement number 755021. For more information, visitwww.hitcf.org.

About Proteostasis Therapeutics, Inc.

Proteostasis Therapeutics, Inc.is a clinical stage biopharmaceutical company developing small molecule therapeutics to treat cystic fibrosis and other diseases caused by dysfunctional protein processing. Headquartered inBoston, MA, theProteostasis Therapeuticsteam focuses on identifying therapies that restore protein function. For more information, visitwww.proteostasis.com.

Safe Harbor

This release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including but not limited to statements regarding the potential of PTI drug combinations, expectations regarding ex vivotesting of our proprietary combinations in organoids and clinical evaluation in CF patients, the expected timing for enrollment, completion and reporting of results of our CHOICES Phase 3 clinical trial, our commitment to expanding available therapeutic options for CF patients and the intended goals of the CHOICES trial and the ability to serve as a potential basis for future marketing approval. Words such as "aim," "may," "will," "expect," "anticipate," "estimate," "intend," and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially from those expressed or implied by the forward-looking statements, and we, therefore cannot assure you that our plans, intentions, expectations or strategies will be attained or achieved. Such risks and uncertainties include, without limitation, the potential of our proprietary combination therapies for the treatment of CF, the potential benefit of our proprietary combination therapies to patients, expected completion of our clinical studies and cohorts for our clinical programs, initiation of a pivotal or registrational study, the possibility final or future results from our drug candidate trials (including, without limitation, longer duration studies) do not achieve positive results or are materially and negatively different from or not indicative of the preliminary results reported by the Company (noting that these results are based on a small number of patients and small data set), uncertainties inherent in the execution and completion of clinical trials (including, without limitation, the possibility that FDA or other regulatory agency comments delay, change or do not permit trial commencement, or intended label, or the FDA or other regulatory agency requires us to run cohorts sequentially or conduct additional cohorts or pre-clinical or clinical studies), in the enrollment of CF patients in our clinical trials in a competitive clinical environment, in the timing of availability of trial data, in the results of the clinical trials, in possible adverse events from our trials, in the actions of regulatory agencies, in the endorsement, if any, by therapeutic development arms of CF patient advocacy groups (and the maintenance thereof). For a discussion of other risks and uncertainties, and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, see the section entitled "Risk Factors" in our most recent Form 10-Q, as well as discussions of potential risks, uncertainties, and other important factors in our subsequent filings with the Securities and Exchange Commission. We assume no obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, unless required by law.

CONTACTS:

Investors:David Pitts / Claudia StyslingerArgot Partners212.600.1902david@argotpartners.com/ claudia@argotpartners.com

Media:David RosenArgot Partners212.600.1902david.rosen@argotpartners.com

HIT-CF Project Coordination:HIT-CF ConsortiumUniversity Medical Centre Utrecht (The Netherlands)HITCF@umcutrecht.nl

i Berkers et al, Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis Cell Reports 26, 17011708,February 12, 2019

View original content:http://www.prnewswire.com/news-releases/proteostasis-therapeutics-and-cf-europe-announce-completion-of-patient-enrollment-for-choices-the-first-ever-personalized-medicine-based-study-in-cystic-fibrosis-301009650.html

SOURCE Proteostasis Therapeutics, Inc.

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Proteostasis Therapeutics and CF Europe Announce Completion of Patient Enrollment for CHOICES, the First-Ever Personalized Medicine-Based Study in...

Austin Aries Confirms Why He Was At AEW Dynamite This Week – 411mania.com

By Stem Cell Clinic

It was reported earlier this week that both DDP and Austin Aries were at this weeks AEW Dynamite taping, where it was rumored they were pitching a stem cell venture to the company.

Aries confirmed the story, noting that he works for the company Bioxcellerator, a stem cell therapy clinic.

He told Bodyslam.net: I work for BioX. I did have meetings about partnerships and collaborations with both DDP and DDPY Brand as well as AEW.

He previously revealed on Instagram that he joined the company as the Director of Athletic Performance Division.

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BIG ANNOUNCEMENT!!! . Many of you know that I went down to Medellin, Colombia in December for @bioxcellerator_ #stemcelltherapy, and now after a couple months, my neck and lower back feel really good. I was honestly so impressed with the entire @bioxcellerator_ operation. So much so, that upon returning I had conversations about joining the @bioxcellerator_ team in some capacity. . With that, I am EXTREMELY EXCITED TO ANNOUNCE that I have officially joined BioXcellerator as Director Of Athletic Performance Division. My role will be to continue connecting high level athletes, entertainers and influencers with all the amazing benefits of @bioxcellerator_ #stemcelltherapy. As someone whose passion is helping people, I couldnt pass up the opportunity to be a part of this company that is changing lives with their cutting edge #stemcelltherapy. . So, anyone whos been thinking about, or interested in finding out more about BioXcellerator stem cell therapy, Im your guy! Please DM or email me at [emailprotected] Heres to all our improved health and happiness in 2020 and beyond! . . #bioxcellerator #bioxmen #bioxwomen #stemcell #stemcells #stemcelltherapy #medellin #colombia

A post shared by Austin Aries (@austinhealyaries) on Feb 17, 2020 at 8:49am PST

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Austin Aries Confirms Why He Was At AEW Dynamite This Week - 411mania.com

Plant Stem Cell Market: Segmentation, Industry trends and Development to 2016 2024 – Instant Tech News

By Stell Cell Research

The Most Recent study on the Plant Stem Cell Market Research provides a profound comprehension of the various market dynamics like trends, drivers, the challenges, and opportunities. The report further elaborates on the micro and macro-economic elements that are predicted to shape the increase of the Plant Stem Cell market throughout the forecast period (2019-2029).

The introduced study elucidates the crucial indicators of Market growth which comes with a thorough analysis of this value chain, CAGR development, and Porters Five Forces Analysis. This data may enable readers to understand the quantitative growth parameters of this international industry that is Plant Stem Cell .

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The Plant Stem Cell market report focuses on major growth trajectories such as drivers, restraints, challenges and opportunities that will have a significant impact on the incontinence devices market growth in the forecast duration. Besides this, the report lists various segments of the market and the competitive landscape of the market with base and forecast figures and the estimated CAGRs. Adding to that, the list of significant players and their plan of action for drawing better revenues is available in the report. Furthermore, key industry developments and interesting insights into the market, along with current incontinence devices market trends, are also provided in the report.

competitive landscape and key product segments

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Plant Stem Cell Market: Segmentation, Industry trends and Development to 2016 2024 - Instant Tech News

3D Cell Culture Market 2019 Insights on Trends, Application, Types & Users Analysis 2025 | Thermo Fisher Scientific, Nanofiber Solutions, Advanced…

By Stell Cell Research

3D cell culture market trends are increasing in the occurrence of cancer. Use of 3D cultures in the detection of the phenotypic changes is encouraging the acceptance of healthcare facilities and the activities of R&D. Growth in the acceptance of organ transplantation and tissue engineering for chronic diseases is anticipated to fuel the research during the forecast period.

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Moreover, for implementing the culture by using micro-fabricated tissue component is projected to offer the 3D cell culture market with various opportunities. For the better representation, it is very important to incorporate the 3D cell culture system in the activities of research are fueling the development of new methods and materials, boosting the global 3D cell culture market growth.

3D cell culture market trends are increasing in the occurrence of cancer. Use of 3D cultures in the detection of the phenotypic changes is encouraging the acceptance of healthcare facilities and the activities of R&D. The advantages completed by the use of 3D in the stem cells and oncology are providing various opportunities leveraged for the development of 3D cell culture in the therapeutic purposes in the future. 3D cell culture is appropriate for the modeling because of the similarity they offer to the morphology of cells or organs. Various options of 3D cell culture are available on the basis of scaffold-free, 3D bioreactor system and scaffold-based. The appearance of the protocols, kits, and 3D optimized assays with the maturity in the different assay techniques development is propelled to supplement the 3D cell culture market growth.

Increase in the research activities related to the rise in the organizations investing in the development of 3D cell culture is expected to boost the 3D cell culture market across the globe. Investments by the research organizations and manufacturers, 3D cell culture market is burgeoning because of the growth in the demand for the organ transplantation. This is expected to be the important factors responsible for the growth of 3D cell culture market. Using the animals in the testing and the research activities of pharmaceuticals, where 3D cell culture can be a substitute for an animal used for the testing and research purpose and will play a major role in the development of 3D cell culture market in the coming years. Laboratories, biotechnology entities, hospitals, pharma companies, and research institutes are progressively developing the 3D cell culture market. Growth in the usage of the 3D cell culture technique in pharmaceuticals for studying the drug doses impact will foster the 3D cell culture market during the forecast period.

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Global 3D cell culture market was segmented into end-user, application, product type, and region. Based on end-user, 3D cell culture market is divided into academic institutes, contract research laboratories, and pharmaceutical & biotechnology companies. Based on application, the market is divided into regenerative medicine, drug discovery, stem cell research, and cancer research. On the basis of product type, the market is divided into services, microchips, bioreactors, gels, and scaffold-based platforms. Scaffold-based platforms are further sub-divided into scaffold-free platforms, solid scaffolds, nano-porous scaffolds, micro-porous scaffolds, and macro-porous scaffolds.

Geographically, regions involved in the global 3D Cell Culture market are Europe, North America, Asia Pacific, Latin America, and Middle East & Africa. Europe is dominating the 3D cell culture market. North America holds the largest 3D cell culture market share.

Key players involved in the global 3D cell culture market are Thermo Fisher Scientific, Nanofiber Solutions, Advanced Biomatrix, Dickinson and Company and more.

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Key Segments in the Global 3D Cell Culture Market are-

By End-User, market is segmented into:

By Application, market is segmented into:

By Product Type, market is segmented into:

By Regions market is segmented into:

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3D Cell Culture Market 2019 Insights on Trends, Application, Types & Users Analysis 2025 | Thermo Fisher Scientific, Nanofiber Solutions, Advanced...

NASA to send equipment to International Space Station to research Improving Shoes, Showers, 3D Printing – Clarksville Online

By Stell Cell Research

Houston, TX A variety of science investigations, along with supplies and equipment, launch to the International Space Station on the 20th SpaceX commercial resupply services mission.

The Dragon cargo spacecraft is scheduled to leave Earth March 2nd from Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida. Its cargo includes research on particle foam manufacturing, water droplet formation, the human intestine and other cutting-edge investigations.

Airbus workers unpack the Bartolomeo platform at NASAs Kennedy Space Center in Florida in preparation for its launch to the International Space Station. The platform, manufactured by Airbus Defence and Space, hosts multiple external payloads in low-Earth orbit. (NASA)

The space station, now in its 20th year of continuous human presence, provides opportunities for research by government agencies, private industry, and academic and research institutions.

Such research supports Artemis, NASAs missions to the Moon and Mars, and leads to new technologies, medical treatments and products that improve life on Earth.

Particle foam molding is a manufacturing process that blows thousands of pellets into a mold where they fuse together. The shoe company Adidas uses this process to make performance midsoles, the layer between the sole of a shoe and the insole under your foot, for its products.

The BOOST Orbital Operations on Spheroid Tesellation (Adidas BOOST) investigation looks at how multiple types of pellets behave in this molding process. Using one type of pellet creates a foam with the same properties throughout the sole component. Using multiple pellet types can allow engineers to change mechanical properties and optimize shoe performance and comfort. Removing gravity from the process enables a closer look at pellet motion and location during the process.

Results of this investigation could demonstrate the benefits of microgravity research for manufacturing methods, contributing to increased commercial use of the space station. New processes for particle foam molding could benefit a variety of other industries, including packaging and cushioning materials.

The Bartolomeo facility, created by ESA (European Space Agency) and Airbus, attaches to the exterior of the European Columbus Module. Designed to provide new scientific opportunities on the outside of the space station for commercial and institutional users, the facility offers unobstructed views both toward Earth and into space.

Airbus is collaborating with the United Nations Office of Outer Space Affairs to offer UN Member States the opportunity to fly a payload on Bartolomeo. Developing countries are particularly encouraged to participate, and the mission is devoted to addressing the UNs Sustainable Development Goals. Bartolomeo is named for the younger brother of Christopher Columbus.

Droplet Formation Studies in Microgravity (Droplet Formation Study) evaluates water droplet formation and water flow of Delta Faucets H2Okinetic showerhead technology. Reduced flow rates in shower devices conserve water, but also can reduce their effectiveness.

That can cause people to take longer showers, undermining the goal of using less water. Gravitys full effects on the formation of water droplets are unknown, and research in microgravity could help improve the technology, creating better performance and improved user experience while conserving water and energy.

Insight gained from this investigation also has potential applications in various uses of fluids on spacecraft, from human consumption of liquids to waste management and use of fluids for cooling and as propellants.

Human intestine cells forming microvilli inside Emulates Intestine-Chip. (Emulate)

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company Emulates human innervated Intestine-Chip (hiIC). This Organ-Chip device enables the study of organ physiology and diseases in a laboratory setting. It allows for automated maintenance, including imaging, sampling, and storage on orbit and data downlink for molecular analysis on Earth.

A better understanding of how microgravity and other potential space travel stressors affect intestine immune cells and susceptibility to infection could help protect astronaut health on future long-term missions. It also could help identify the mechanisms that underlie development of intestinal diseases and possible targets for therapies to treat them on Earth.

Self-assembly and self-replication of materials and devices could enable 3D printing of replacement parts and repair facilities on future long-duration space voyages. Better design and assembly of structures in microgravity also could benefit a variety of fields on Earth, from medicine to electronics.

Called self-assembled colloidal structures, these are vital to the design of advanced optical materials, but control of particle density and behavior is especially important for their use in 3D printing. Microgravity provides insight into the relationships among particle shape, crystal symmetry, density and other characteristics.

Functional structures based on colloids could lead to new devices for chemical energy, communication, and photonics.

The Multi-use Variable-g Platform (MVP) used for the MVP Cell-03 experiment, shown with the MVP door removed and two carousels inside. (Techshot Inc.)

Generation of Cardiomyocytes From Human Induced Pluripotent Stem Cell-derived Cardiac Progenitors Expanded in Microgravity (MVP Cell-03) examines whether microgravity increases the production of heart cells from human-induced pluripotent stem cells (hiPSCs).

HiPSCs are adult cells genetically reprogrammed back into an embryonic-like pluripotent state, which means they can give rise to several different types of cells. This makes them capable of providing an unlimited source of human cells for research or therapeutic purposes.

For MVP Cell-03, scientists induce the stem cells to generate heart precursor cells, then culture those cells on the space station for analysis and comparison with cultures grown on Earth.

These heart cells or cardiomyocytes (CMs) could help treat cardiac abnormalities caused by spaceflight. In addition, scientists could use them to replenish cells damaged or lost due to cardiac disease on Earth and for cell therapy, disease modeling and drug development. Human cardiac tissues damaged by disease cannot repair themselves, and loss of CMs contributes to eventual heart failure and death.

These are just a few of the hundreds of investigations currently aboard the orbiting laboratory. For daily updates, follow @ISS_Research, Space Station Research and Technology News or our Facebook. Follow the ISS National Lab for information on its sponsored investigations. For opportunities to see the space station pass over your town, check out Spot the Station.

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NASA to send equipment to International Space Station to research Improving Shoes, Showers, 3D Printing - Clarksville Online

Artificial Blood Substitutes Market Overview, Analysis, Trends, Size, Outlook and Forecast to 2028 – News Parents

By Stell Cell Research

Artificial Blood Substitutes Market: Overview

The global artificial blood substitutes market is predicted to register stellar growth rate in the forthcoming years. The presence of a large patient population that requires blood transfusion during surgeries, trauma, and for other blood disorders, which remains unmet due to shortage of blood supply has necessitated creation of artificial blood substitutes.

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Artificial blood substitutes are primarily used to mimic oxygen carrying capacity of biological blood and expand the blood volume in the human body. Use of artificial blood substitutes is at present considered an alternate method for blood transfusion. Further research is underway to develop more alternate methods for blood transfusion, including developing human red blood cells (RBCs) from stem cells of donors blood.

The research report provides an in-depth analysis of the artificial blood substitutes market over the forecast period. The report covers each and every key aspect pertinent to the market, including market dynamics, segmentation, and competitive scenario. The assessment of artificial blood substitutes market presented herein could serve as a valuable guide for both existing market participants, and the ones seeking entry in this market.

Artificial Blood Substitutes Market: Competitive Landscape and Notable Developments

The initial clinical trials for blood substitutes are recorded as early as early 1600, wherein milk, beer, urine, sheeps blood, and perfluorochemicals were administered as blood substitutes for animal and human subjects.

In successive periods, clinical trials of milk transfusion, including goats milk in large quantities were carried out but in vain. Clinical trials also involved injecting human milk that were futile too, which led researchers concede human milk not to be a substitute for blood.

With continual extensive research, over long periods, scientists have attained some success to develop blood substitutes. Artificial blood thus far developed can substitute red blood cells. While biological human blood performs several different functions, artificial blood performs the sole purpose of transporting oxygen and carbon dioxide in the body.

Established biotechnology companies in the ambit are engaged to develop blood substitutes. Such pursuits primarily involve developing oxygen carriers similar or above the capacity of biological blood. With concerted efforts of some top-notch biotechnology companies, namely HEMARINA SA, KaloCyte Inc. and Hemoglobin Oxygen Therapeutics LLC blood substitutes are available as oxygen carrier based on hemoglobin and perfluorocarbon-based oxygen carrier.

Nevertheless, presence of several well-established biotechnology companies engaged in the development of blood substitutes portrays a competitive yet moderately consolidated vendor landscape of the artificial blood substitutes market.

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Artificial Blood Substitutes Market: Key Trends

Worldwide, excessive blood loss due to traumatic injuries and diseases is responsible for vast number of deaths every year. Limited availability of fresh blood and small storage periods of fresh blood for such situations have necessitated development of artificial blood substitutes.

With continual experiments over long periods, scientists have thus far been able to create substitutes to mimic oxygen carrier capacity of biological blood. Development of perfluorochemical-based oxygen carrier and hemoglobin-based oxygen carrier and provide thrust to the artificial blood substitutes market.

Besides this, advent of stem cell therapy is poised to create new opportunities for demand of artificial blood substitutes.

However, on the downside, lower shelf life of artificial blood products and stringent regulatory approval process for these products restrain the growth of artificial blood substitutes market.

Artificial Blood Substitutes Market: Regional Outlook

North America is at the fore for demand within overall artificial blood substitutes market. Presence of advanced healthcare combined with awareness of individuals for alternate demonstrated therapies account for leading revenue share of the region.

Continual advances in stem cell therapy further indicates sustained growth of artificial blood substitutes market in the region.

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Artificial Blood Substitutes Market Overview, Analysis, Trends, Size, Outlook and Forecast to 2028 - News Parents

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