Stem Cell Clinic

Gary Pesselt: Vitality Healthcare is it worth the cost? – The Union of Grass Valley

Another seminar is again advertised in The Union. I first thought it might help my wife with neuropathy until I did some extensive research.

First off, Medicare does not cover stem cell injections. Bone marrow stem cell injections range from $2,000 to $5,000 or more. Read Consumer Research report at: https://www.consumerreports.org/medical-treatments-procedures/trouble-with-stem-cell-therapy.

Stem cell treatments are widely accepted only for two broad medical indications: to help treat a handful of blood disorders including leukemia and some forms of anemia and in some cases to help burn victims. Ask questions. Any doctor who offers stem cell therapy should be able to explain where the cells will come from, what will be done to them before theyre injected into your body, and how, exactly, they will resolve your illness or injury. He or she should also be able to offer you proof of safety and efficacy, even for experimental treatments. Dont rely on patient testimonials.

Stem cells survive much longer than ordinary cells, increasing the chance that they might accumulate genetic mutations. It might take only a few mutations for one cell to lose control over its self-renewal and growth and become the source of cancer. Please do your own research.

Gary Pesselt

Grass Valley

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Gary Pesselt: Vitality Healthcare is it worth the cost? - The Union of Grass Valley

Stem Cell Banking Market to Witness Robust Expansion throughout the Forecast 2017-2023: : Allied Market Research – GuruFocus.com

Stem cells can repair and self-renewal damaged cells and can thus be used to treat various medical conditions. These cells are stored as they have the potential for usage in the treatment of any medical conditions that the person can further from in the future. The collected stem cells are cryopreserved and stored for decades, which can be later used to treat large number of chronic diseases such as leukemia, thalassemia, and diabetes.

The global stem cell banking market was valued at $1,986 million in 2016, and is estimated to reach $6,956 million by 2023, registering a CAGR of 19.5% from 2017 to 2023. North America is the highest contributor in the stem cell banking market in 2016; however, Asia-Pacific is expected to witness the highest growth rate during the forecast period.

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Rise in number of births occurring globally, increase in R&D activities in regards with applications of stem cells, and surge in prevalence of fatal chronic diseases drive the growth of the market. The growth in GDP & disposable income globally is projected to help increase the number of stem cell units stored, which in turn boosts the market growth. However, legal and ethical issues related to stem cell collections and lack of acceptance and awareness in the developing regions are projected to hinder the market growth.

Among the cell type, the umbilical cord stem cell segment dominates the market, as these stem cells can be used to treat almost 80 diseases and the extraction process is easy and does to harm the newborn in any way. However, the adult stem cell segment is expected to register the highest growth rate during the forecast period.

Depending on bank type, the private stem cell banking is the dominant segment in the stem cell banking market. Although the number of public banks are more than private banks, the revenue generated by private stem cell banks are more, which contributes toward the growth of the market.

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Key Findings of the Stem Cell Banking Market:

Used stem cells is projected to grow at the highest rate among the utilization segment during the analysis period.

North America dominated global stem cell banking market in 2016, and is projected to continue its dominance in future.

China is expected to grow at the highest rate in the Asia-Pacific region during the forecast period.

Storage service segment was the largest contributor among the service type segments in 2016.

The private stem cell bank generated the highest revenue, and is expected to continue its dominance in future.

In 2016, North America was the major revenue contributor, owing to increase in awareness toward the benefits of storing stem cell and favorable regulatory scenario. However, Asia-Pacific is expected to witness the highest CAGR during the analysis period, due to high birth rate in populace countries such as India and China.

The key players operating in the global stem cell banking market include Cord Blood Registry, ViaCord, Cryo-Cell, China Cord Blood Corporation, Cryo-Save, New York Cord Blood Program, CordVida, Americord, CryoHoldco, and Vita34. Other prominent players in the value chain include Caladrius Biosciences, Cryoviva, Smart Cells International Ltd., Stemade Biotech, Cytori Therapeutics, Cellular Dynamics International, PerkinElmer, and Reelabs.

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Stem Cell Banking Market to Witness Robust Expansion throughout the Forecast 2017-2023: : Allied Market Research - GuruFocus.com

Stem Cell Therapy Market by Treatment,Application,End Users and Geography Forecast To 2026 – Weekly Spy

Stem Cell Therapy Market is expected to reach 202.77 billion by 2026 from 12.25 billion in 2017 at CAGR of 42.02%.(Detailed analysis of the market CAGR is provided in the report) stands for use of stem cells to treat or prevent disease or condition.Stem Cell Therapy Market

Bone marrow transplant and some therapies derived from umbilical cord blood are mainly used in stem cell therapy. Advancement, in order to establish new sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions, are increased in recent years. Stem Cell Therapy Market Researchers are making efforts to discover novel methods to create human stem cells. This will increase the demand as well as supply for stem cell production and potential investigation in disease management. Increasing investment & research grants for developing safe and effective stem cell therapy products, the growing patient base for target diseases, concentrated product pipelines, increasing approval of the new clinical trials, rapid technological advancement in genomics, and the rising awareness about the stem cell are expected to drive the growth of the Stem Cell Therapy solutions market during the forecast period.

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However, improper infrastructure, insufficient storage systems, nascent technology in underdeveloped economies, Ethical issues related to an embryonic stem cell, low patient acceptance rate, Difficulty in the preservation of stem cell are expected to restrain the market growth. North America is expected to be the largest growing region by 2026; the reason behind that is extensive funding by Government. However, Emerging countries like India, china, Korea have low growth rate as compared to Developed regions in 2017 but increase in awareness about stem cell therapy will lead the Asia Pacific to generate a significant level of revenue by 2026.Key Highlights of Stem Cell Therapy Market report

Detailed quantitative analysis of the current and future trends from 2017 to 2026, which helps to identify the prevailing market opportunities.Comprehensive analysis of factors instrumental in changing the market scenario, rising prospective opportunities, market shares, core competencies in terms of market development, growth strategies and identification of key companies that can influence this market on a global and regional scale.Assessment of Market definition along with the identification of key drivers, restraints opportunities and challenges for this market during the forecast period.Complete analysis of micro-markets with respect to individual growth trends, prospects, and contributions to the overall Stem Cell Therapy Solutions market.Stem Cell Therapy market analysis and comprehensive segmentation with respect to the Application, End users, Treatment, and geography to assist in strategic business planning.Stem Cell Therapy market analysis and forecast for five major geographies-North America, Europe, Asia Pacific, Middle East & Africa, Latin America, and their key regions.For company profiles, 2017 has been considered as the base year. In cases, wherein information was unavailable for the base year, the years prior to it have been considered.

Research Methodology:

The market is estimated by triangulation of data points obtained from various sources and feeding them into a simulation model created individually for each market. The data points are obtained from paid and unpaid sources along with paid primary interviews with key opinion leaders (KOLs) in the market. KOLs from both, demand and supply side were considered while conducting interviews to get an unbiased idea of the market. This exercise was done at a country level to get a fair idea of the market in countries considered for this study. Later this country-specific data was accumulated to come up with regional numbers and then arrive at a global market value for the stem cell therapy market.

Key Players in the Stem Cell Therapy Market are:

Chiesi Farmaceutici S.P.A Are:Gamida CellReNeuron Group, plcOsiris Therapeutics, Inc.Stem Cells, Inc.Vericel Corporation.Mesoblast, Ltd.

Key Target Audience:

Stem Cell Associations and OrganizationsGovernment Research Boards and OrganizationsResearch and consulting firmsStem Cell Therapy Market InvestorsHealthcare Service Providers (including Hospitals and Diagnostic Centers)Stem Cell Therapeutic Product Manufacturing OrganizationsResearch LabsClinical research organizations (CROs)Stem Cell Therapy Marketing PlayersPharmaceutical Product Manufacturing Companies

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Scope of the Stem Cell Therapy Market Report:

Stem Cell Therapy market research report categorizes the Stem Cell Therapy market based on Application, End users, Treatment, and geography (region wise). Market size by value is estimated and forecasted with the revenues of leading companies operating in the Stem Cell Therapy market with key developments in companies and market trends.Stem Cell Therapy Market, By Treatments:

Allogeneic Stem Cell TherapyAutologous Stem Cell Therapy

Stem Cell Therapy Market, By End Users:HospitalsAmbulatory Surgical CentersStem Cell Therapy Market, By Application:OncologyCentral Nervous System DiseasesEye DiseasesMusculoskeletal DiseasesWound & InjuriesMetabolic DisordersCardiovascular DisordersImmune System DisordersStem Cell Therapy Market, By Geography:

North AmericaEuropeAsia PacificMiddle East & AfricaLatin America

MAJOR TOC OF THE REPORT

Chapter One: Stem Cell Therapy Market Overview

Chapter Two: Manufacturers Profiles

Chapter Three: Global Stem Cell Therapy Market Competition, by Players

Chapter Four: Global Stem Cell Therapy Market Size by Regions

Chapter Five: North America Stem Cell Therapy Revenue by Countries

Chapter Six: Europe Stem Cell Therapy Revenue by Countries

Chapter Seven: Asia-Pacific Stem Cell Therapy Revenue by Countries

Chapter Eight: South America Stem Cell Therapy Revenue by Countries

Chapter Nine: Middle East and Africa Revenue Stem Cell Therapy by Countries

Chapter Ten: Global Stem Cell Therapy Market Segment by Type

Chapter Eleven: Global Stem Cell Therapy Market Segment by Application

Chapter Twelve: Global Stem Cell Therapy Market Size Forecast (2019-2026)

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Stem Cell Therapy Market by Treatment,Application,End Users and Geography Forecast To 2026 - Weekly Spy

Ixazomib Extends Survival in Multiple Myeloma for Patients Not Treated With Stem Cell Transplantation – Pharmacy Times

Ixazomib Extends Survival in Multiple Myeloma for Patients Not Treated With Stem Cell Transplantation

The phase 3 TOURMALINE-MM4 study evaluated single-agent oral ixazomib as first-line maintenance therapy versus placebo in 706 adult patients diagnosed with MM not treated with stem cell transplantation, who have completed 6 to 12 months of initial therapy and achieved a partial response or better.

New data from the study have demonstrated statistically significant improvement in PFS, meeting the primary endpoint of the trial, Takeda announced. According to the press release, this is the first industry-sponsored phase 3 trial to investigate the concept of switch maintenance, the use of medications not included in initial induction therapy, in this setting.

First approved by the FDA in November 2015, ixazomib is an oral proteasome inhibitor being studied across several MM treatment settings, according to Takeda. It is currently indicated in combination with lenalidomide and dexamethasone for the treatment of patients with MM who have received at least 1 prior therapy.

The TOURMALINE clinical development program includes ongoing clinical trials involving ixazomib in MM:

Reference

Phase 3 Trial Ninlaro (ixazomib) as First Line Maintenance Therapy Met Primary Endpoint in Multiple Myeloma Patients not treated with Stem Cell Transplantation [news release]. Takedas website. https://www.takeda.com/newsroom/newsreleases/2019/phase-3-trial-of-ninlaro-ixazomib-as-first-line-maintenance-therapy-met-primary-endpoint-in-multiple-myeloma-patients-not-treated-with-stem-cell-transplantation/. Accessed November 7, 2019.

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Ixazomib Extends Survival in Multiple Myeloma for Patients Not Treated With Stem Cell Transplantation - Pharmacy Times

Phase III trial of Ninlaro as first-line maintenance therapy meets PFS in multiple myeloma – The Cancer Letter

publication date: Nov. 8, 2019

The phase III Takeda TOURMALINE-MM4 study met its primary endpoint of progression-free survival in multiple myeloma not treated with stem cell transplantation.

The trial evaluated the effect of single-agent oral Ninlaro (ixazomib) as a first-line maintenance therapy versus placebo, and demonstrated statistically significant improvement in PFS, according to Takeda. TOURMALINE-MM4 is the first industry-sponsored phase III trial to explore the concept of switch maintenance, the use of medicines not included in initial induction therapy, in this setting.

Ninlaro is not approved for this specific use.

TOURMALINE-MM4 is a randomized, placebo-controlled, double-blind phase III study of 706 patients who have completed 6-12 months of initial therapy and achieved a partial response or better.

Inovio demonstrates 80% 6-month PFS in phase II glioblastoma multiforme study with INO-5401 + Libtayo

A phase II study (NCT03491683) of newly diagnosed glioblastoma multiforme combining Inovios INO-5401 and INO-9012 in combination with Libtayo (cemiplimab) showed that 80% (16 of 20) of MGMT gene promoter methylated patients and 75% (24 of 32) of unmethylated patients were progression-free at six months measured from the time of their first dose (n = 52), substantially exceeding historical standard-of-care data.

INO-5401 is a T cell-activating immunotherapy encoding for three tumor-associated antigens (hTERT, WT1, and PSMA). INO-9012 is an immune activator encoding IL-12, and Libtayo is a PD-1 blocking antibody developed by Regeneron Pharmaceuticals in collaboration with Sanofi.

The data were to be presented at the Society for Immunotherapy of Cancer 2019 Annual Meeting in National Harbor, MD, Nov. 6-10.

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Phase III trial of Ninlaro as first-line maintenance therapy meets PFS in multiple myeloma - The Cancer Letter

Tales of medical misinformation and misadventures – Stuff.co.nz

There's an old saying that "if you have your health, then you have everything".

Modern healthcare and society's approach to diseaseare covered in some new podcasts that are worth taking a deep diveinto.

Popculture podcast Endless Threadfinds weekly subject matter by diving into the enormousonline communities which congregate on Reddit. Presenters Ben Brock Johnson and Amory Sivertsonhave released a special five-part series called Infectious, which focuses on recent measles epidemics and the rise of the anti-vaccination movement.

At the centre of this story is the internet and the ways in which misinformation about vaccines and mistrust of medicines has been spread. This is a well-researched documentary series featuring medical experts, public health officials and parents and seeks to untangle fact from fiction.

Ben Brock Johnson, left, and Amory Sivertson, right, host the Endless Thread podcast, which dives into the world of vaccines and anti-vaxxers.

READ MORE:* Cryptoqueens and scam goddesses: Exploring fraud via podcasts* Podcasts that are an ode to nature* Why you need to listen to Dolly Parton's America

ENDLESS THREAD

The Endless Thread podcast delves into Reddit's vast communities to explore some of the most compelling stories the Internet has to offer.

Last Dayalso tackles an epidemic but in this case it is the United States' opioid crisis as seen through the lenses of family members who have lost a relative to an opioid overdose. The first episode charts the last day of life of presenterStephanie Wittels Wachs' brother, Harris Wittels, who died of an overdose at the age of 30 in 2015.

He was a comedian and TV writer who wrote for The Sarah SilvermanShow and Aziz Ansari's Master of None. This series provides a deeply personal look at the disease of addiction and how we as a society treat those suffering from it.

Stem cell treatment has been touted as a miracle option for pain and healing in patients and the latest Wondery podcast examines what happens when patients in Texas get a bad batch of stem cells.

Presented by medical journalist, Laura Biel, who also presented the hugely popular Dr Death podcast, Bad Batch exposes greed and desperation in this highly unregulated multi-million dollar industry.

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Tales of medical misinformation and misadventures - Stuff.co.nz