Home – Seattle Stem Cell Center

Dr. Tami is a certified physician in Aesthetic Medicine, and Integrative & Natural Medicine. She is the type of doctor that other doctors go to. Her unique combination of experience and expertise allows her to not only make her patients look great on the outside, but she is also uniquely qualified to treat patients using the newest and most cutting edge medical and nutritional therapies to heal and retard the effects of hard living, illness and age.

Many physicians treat symptoms, Dr. Tami discovers and treats root causes. What that mean for you is a real diagnosis and a program personally tailored for you by one of the top doctors in the country. Despite her high level of training and accolades her approach is holistic and cutting edge. She is committed to increasing the quality of life for all of her patients. She cares about each of her patients and treats them like family.

Additionally, Dr. Tami is on the faculty of the American Academy of Aesthetic Medicine, and lectures around the world on Aesthetics and Bio-identical hormones for men and women as well as the benefits of stem cell therapy. She is featured as the Health and Beauty Expert for King 5 Health Link regularly, has been the health expert for articles for Shape magazine and has hosted two radio shows about Aesthetic Medicine and cutting edge natural medicine and a best selling author.

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Stem Cell Therapy Doctors Scottsdale & Phoenix – Stem Cell …

Human stem cells are in your body to generate new and replacement cells, originating and repairing bone, muscle, cartilage, spinal discs and other specialized cells.

Our stem cell therapy doctors have used stem cell treatments to successfully to treat joint injuries and age-related joint degeneration, including osteoarthritis and osteoporosis.

Medical researchers have known for years that stem-cell therapy treatments have the potential to change the face of human aging and alleviate suffering. The capacity for stem cells to self-renew and give rise to ensuing generations offers potential for groups of tissues that can potentially replace diseased and damaged areas in the body, with minimal risk of rejection and side effects.

Your stem cells can buildnewcartilage, ligament and tendon tissue and restore the joints original function. Stem-cell therapy treatment is an alternative to joint replacement surgery. It is non-surgical and minimally invasive. It is low-risk: it doesnt permanently alter your structure with foreign materials as with joint replacement surgery. It leaves your options open.

Stem cells are the big guns of regenerative joint-repair therapy. The treatment concentrates your own stem cells at the site of an injury to exploit their ability to develop into the specific cell types needed to repair and restore your injured joint.

For stem-cell treatment, we will collect stem cells from your body, concentrate them and then precisely place them where healing is needed. Your bodys own healing process will take over from there.

Many of our patients have experienced significantly reduced pain with stem cell therapy we provide in Scottsdale and Phoenix, AZ.

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Stem Cell Therapy Doctors Scottsdale & Phoenix - Stem Cell ...

Find a stem cell transplant provider | CTCA

A stem cell transplant is a procedure that infuses healthy cells into the body to replace diseased or damaged bone marrow. Stem cell transplants are commonly used to treat cancers that affect the blood and lymphatic systems. Those cancers include leukemia, multiple myeloma, non-Hodgkin lymphoma and Hodgkin lymphoma. This treatment may also help patients recover from cancer treatments such as radiation therapy and chemotherapy.

The doctors who perform stem cell transplants at Cancer Treatment Centers of America (CTCA) are hematologists and/or medical oncologists who focus on treating hematologic cancers. These oncologists perform two main types of stem cell transplantation. Autologous transplant is a procedure where cells are collected from the patient's own bloodstream (peripheral blood stem cells). The cells are then frozen and stored, and after intensive therapy, they are transplanted in the patient. The other type of stem cell transplants are called allogeneic. This procedure involves harvesting stem cells from a donor whose tissue closely matches the patient.

It may take time after a stem cell transplant to rebuild your immune system to healthy levels. Your doctors actively monitor you in the weeks following the transplant and check your blood counts frequently. Doctors may prescribe medications, if necessary, and may perform blood transfusions to address infections or bleeding problems after the stem cell transplants.

To reduce the risk of complications and side effects, the stem cell transplant teams at our five CTCA hospitals, located across the United States, work with you to address your needs throughout the stem cell transplant process. The stem cell transplant team collaborates with other members of the patients care team, including supportive care clinicians who offer mind-body medicine, oncology rehabilitation, nutrition therapy, chiropractic care and other therapies to help manage side effects and improve the patients quality of life.

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Find a stem cell transplant provider | CTCA

StemCell | Ohio Stem Cell Treatment Center of Cleveland …

Welcome to OSCTC ! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

Welcome to OSCTC! The Ohio Stem Cell Treatment Center, an affiliate of the Cell Surgical Network (CSN) are devoted to advancing access and quality care in the area of adult stem cell regenerative medicine in order to help people suffering from a variety of inflammatory and degenerative conditions

Learn More

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StemCell | Ohio Stem Cell Treatment Center of Cleveland ...

stem cell doctors Archives – Stem Cell Therapy Phoenix

Elbow problems? You might suffer from lateral epicondylitis, most commonly known as tennis elbow, which is not a very accurate name considering that most professional tennis players never suffered from this condition. It often occurs to lots of individuals suffering from repetitive stress who do...

There are only a limited number of non-surgical options available in the treatment of arthritis. A large amount of treatments currently in use focus on providing symptomatic relief for the pain caused by arthritis, but do not provide a means to repair the damage that...

Achilles tendonitis, also known as Achilles tendinopathy is attributed to the overuse of the Achilles tendon. This is a common sports injury and one that it is also very difficult to treat since this is an area where there is poor blood circulation and cell...

There is a new branch of medicine forming to assist those who have suffered significant damage to the cartilage of their joints; whether by arthritic degradation or injury. Since cartilage does not regrow normally very well in the body without outside stimulation -such as microfracture surgery...

Both PRP and bone marrow stem cell injections are used in regenerative medicine. The two have been the subject of much interest over the past few years as clinical studies have been conducted to ascertain their benefits and uses in different treatments. Most patients with...

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stem cell doctors Archives - Stem Cell Therapy Phoenix

Our Doctors – Knee Stem Cells

Dennis M. Lox, M.D. Knee Stem Cell Treatments have been seen Across The Nation.

Dennis M Lox, M.D. is an expert in Knee Stem Cell Injections for those who seek an alternative to the unnecessary complex knee surgery of that in the past by providing Knee Stem Cell Treatment. Dennis M. Lox, M.D. has privately owned Medical Centers that do not partake in the fast chain franchise that other Stem Cell Centers are stuck doing, thus he is able provide a more personalized treatment for your particular injury.

Dennis M. Lox, M.D. centers have a professional, caring environment for patients looking for comfort in their time of need and provids follow-ups on your wellbeing to enhance your recovery. Dennis M. Lox, M.D. has been helping patients since 1990 nationally and internationally and has been the focus of the Stem Cell News Worldwide with his expertise and he continually researches new technologies to further Stem Cell advancements.

PUBLICATIONS:

Lox, D.M., Heine, M.W., and Lox, C.D., Hemostatic Alterations Resulting from Chronic Ethanol Ingestion during Tetracycline Therapy in the Rat, Neurobeh, Toxiocol: Vol. 7, 1985.

Lox, C.D. and Lox, D.M., Effects of Acute Ethanol Intoxication Combined with Secobarbitol Abuse on Homeostasis, General Pharm Vol. 16, 1985. 252-258.

PRESENTATIONS:

Lox, D.M., Sports Medicine and Stem Cells: A Clinical Transformation Presentation at the Select Biosciences Conference: Tissue Engineering and Bio printing, Boston, Massachusetts, February 2015

Lox, D.M., Clinical Regulation of Cytokine and Inflammatory Pathways with Autologous Stem Cell Therapy Presentation at the 17th Clinical Applications for Age Management Medicine Group, The Bellagio Hotel, Las Vegas, Nevada, October 2014

Lox, D.M., Moderator 3rd Annual International Conference on Tissue Science and Regeneration, Valencia, Spain, September 2014

Lox, D.M., Athletes and Avascular Necrosis Presentation at the 3rd Annual International Conference on Tissue Science and Regeneration, Valencia, Spain, September 2014 Lox, D.M., Managing Sports and Arthritic Complaints with Stem Cells, Presentation at the Select Biosciences Clinical Translation of Stem Cells, Palm Desert, California, April 2014

Lox, D.M., A Professional Football Player with Failed Knee Surgery: A Case of Treatment with Adipose Derived Stem Cells, Presentation at the Tissue Engineering and Regenerative Medicine International Society Asia Chapter (Termis AP) Annual Conference, Shanghai, China, Oct. 2013

Lox, D.M., Chronic Foot Pain in a Ballerina: Treatment with Regenerative Medicine Presentation at the Tissue Engineering and Regenerative Medicine International Society Asia Pacific Chapter (Termis AP) Annual Conference, Shanghai, China, October 2013

Lox, D.M., Knee Osteoarthritis: Quality of Life (Q o L) Measures Following Autologous Stem Cell Therapy Presentation at the International Cartilage Repair Society Annual Meeting, Izmir, Turkey, September 2013

Lox, D.M., Cytokine Modulation with Nutraceuticals as a Synergistic Mechanism for Regenerative Grafting in Osteoarthritis Repair Presentation at the Tissue Engineering and Regenerative Medicine International Society Meeting, Istanbul, Turkey, June 2013

Lox, D.M., Arthritis: Quality of Life (Q o L) Measures following Mesenchymal Stem Cell Therapy Presentation at the Tissue Engineering and Regenerative Medicine International Society Meeting, Istanbul, Turkey, June 2013

Lox, D.M., Can Healthcare Outcomes Be Quantified with Stem Cell Therapy in Osteoarthritis?

Presentation at the World Stem Cell Summit, West Palm Beach, Fl. December 2012

Lox, D.M., Regenerative Rehabilitation of an Elite Soccer Player, Presentation at the First Annual Symposium on Regenerative Rehabilitation, Pittsburgh, PA, November 3-4, 2011.

Lox, D.M., Regenerative Medicine and Tissue Engineering: Ethical Concerns with Health Care Reform, Presentation at the 2011 World Stem Cell Summit, Pasadena, CA on October 2011.

Lox, D.M., Autologous Adipose-Derived Stem Cells in the Rehabilitation of a Soccer Player, Presentation at the Stem Cells Europe 2011 Conference, Edinburgh, Scotland on July 2011.

Lox, D.M., Autologous Human Adipose-Derived Mesenchymal Stem Cells in Orthopedic Medicine: A Veterinary Correlate, Presentation at the 2nd North American Veterinary Regenerative Medicine Conference, Lexington, Kentucky on June 2011.

Lox, D.M., Regenerative Medicine Techniques in Musculoskeletal Medicine, Presented at the

11th Annual Conference of the International Neural Transplantation and Repair, Sand Key, FL on May 2011.

Lox, D.M., Current Regenerative Medicine Techniques, Tampa, Florida on July 10, 2010.

Lox, D.M., Complex Regional Pain Syndrome Course Presentation, American Academy of Physical Medicine and Rehabilitation Annual Assembly (Moderator: Dennis M. Lox, M.D. Speakers: Jose Ochoa, M.D., Gabor Racz, M.D., Dennis M. Lox, M.D.); Seattle, Washington on November 5, 1998.

Lox, D.M., New Treatments in Myofascial Pain and Fibromyalgia, Presented at the Morton Plant/Mease Health Education Center Countryside, Florida on December 13, 2001.

Lox, D.M., Acute Spinal and Pain Syndromes Presented to the Pinellas County Primary Care and OB/GYN physicians, sponsored by Knoll Pharmaceuticals, 1998.

Lox, D.M., Complex Musculoskeletal Assessment and Treatment, Presented to the Zenith Insurance Company; Sarasota, Florida on September 28, 1998.

Lox, D.M., Fibromyalgia, Presented to Cigna Health Care Physicians, sponsored by Health South Rehabilitation Corporation; Tampa, Florida on September 19, 1998.

Lox, D.M., Evaluation of the Difficult Pain Patient, Presented to the Pinellas County Orthopedic Journal Club, sponsored by Knoll Pharmaceuticals; Clearwater, Florida on September 8, 1998.

Lox, D.M., Fibromyalgia, Presented to the Travelers Insurance Company, sponsored by Health South Rehabilitation Corporation; Tampa, Florida on August 19, 1998.

Lox, D.M., Complex Pain Management, Presented to the Physicians of Collier County, sponsored by Knoll Pharmaceuticals; Naples, Florida on May 16, 1998.

Lox, D.M., Managing Pain in a Managed Care, Presented to the Pinellas County Podiatric Medical Association Meeting; Clearwater, Florida on April 14, 1998.

Lox, D.M., Complex Regional Pain Syndrome: The Historical Perspective from Bonica and Beyond, Presented at the 7th Annual John J. Bonica Vail Winter Pain Conference, sponsored by the Ohio State University Medical Center, College of Medicine, Department of Anesthesiology; Vail, Colorado on March 1998.

Lox, D.M., Pain Management, Presented to Lee County Physicians, sponsored by Knoll Pharmaceuticals; Ft. Myers, Florida in December 1998.

Lox, D.M., Managing Pain in a Managed Care Environment, Presented to the Pinellas County Physicians, sponsored by Knoll pharmaceuticals; Clearwater, Florida in December 1997.

Lox, D.M., Regional Pain Syndrome Update, Presented at the 74th Annual Meeting of the American Congress of Rehabilitation Medicine Pain ISIG; Boston, Massachusetts in September 1997.

Lox, D.M., Physical Medicine for Women Who Hurt all Over (Physical and Somatization Considerations, and Complex Regional Pain Syndrome Update, Presented at the 9th Annual OB/GYN Summer Symposium, Womens Health Care in the 90s, sponsored by the University of Oklahoma Health Sciences Center College of Medicine, Department of Obstetrics and Gynecology; Jackson Hole, Wyoming in August 1997.

Lox, D.M., Replacing the Terms of Reflex Sympathetic Dystrophy and Sympathetically Maintained Pain-An Uphill Battle, Presented at the 13th Annual Update in Physical Medicine and Rehabilitation, sponsored by the University of Utah School of Medicine, Division of Physical Medicine and Rehabilitation, Park City, Utah, March 1997.

Lox, D.M., Complex Regional Pain Syndrome, Presented to Claim Management, Utilization Management, Case Managers, Adjustors and Supervisors of the Travelers/Aetna Insurance Companies; Orlando, Florida in August 1996.

Lox, D.M., Soft Tissue Injuries/RSD/Fibromyalgia-The Rational or Irrational Approach to Diagnosis and Treatment, Presented to Claim Management, Utilization Management, Case Managers and Supervisors of Travelers Insurance Company; Tampa, Florida, 1996.

Lox, D.M., Overview of the Soft Tissue Injury/RSD/Fibromyalgia-The Rational or Irrational Approach to Diagnosis and Treatment, Presented to the Regional Adjustors and Personnel of Geico Insurance Company; Macon, Georgia in May 1996.

Lox, D.M., Causalgia/RSD/SMP-History and Treatment, Presented during the Re-Employment rules of Florida Workers= Compensation Conference, sponsored by the Southwest Chapter of NARPPS in May 1996 (2 CME credits).

Lox, D.M., RSD-Treatment Options for the 90s, Presented to the Florida Association of Rehabilitation Professionals in the Private Sector (FARPPS) in March 1996 (2 CME credits).

Lox, D.M., Causalgia/RSD/SMP-The 100 Year War, Presented to The Florida Association of Rehabilitation Professionals in the Private Sector in January 1996 (2 CME credits)

Lox, D.M., The Differential Diagnosis of Spinal Injuries, Presented to the Intracorp Rehabilitation Nurses in April 1992 (4 CME credits).

Lox, D.M., A Physiatrist Approach to Industrial Industries, Presented to the Florida Rehabilitation Nurses in May 1991 (4 CME credits).

Lox, D.M., Skiing Injuries: Prevention and Rehabilitation, Presented at the North American Medical and Dental Association Seminar; Vail, Colorado in February 1989.

Lox, D.M., The Failed Back Patient, Presented at the Annual Texas Physical Medicine and Rehabilitation Society Meeting; Austin, Texas in August 1989.

Lox, D.M., Dermatomal Somatosensory Evoked Potentials and Gadolinium-MRI in the Evaluation of Chronic Low Back Pain, Presented at the 50th Annual Session of the American Academy of Physical Medicine and Rehabilitation; San Antonio, Texas in November 1989.

Lox, D.M., The Evaluation and Treatment of Lumbar Spine Disorders, Presented at the University of Texas Health Science Center at San Antonio, Department of Allied Health; San Antonio, Texas in December 1988.

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Our Doctors - Knee Stem Cells

Embryonic stem cells | Cells | MCAT | Khan Academy

An overview of early development of a zygote to an embryo. Embryonic and somatic stem cells. Created by Sal Khan.

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About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.

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Embryonic stem cells | Cells | MCAT | Khan Academy

Crucial Differences Between Non-Embryonic and Embryonic Stem …

July 10, 2009 | by Jan F. Dudt | Topic: Faith & Society Print

We hear a lot about stem cells, which are front-and-center as a major policy debate in America, one that involves science, medicine, ethics, politics, and much more.

What are the issues? Whats at stake? What are embryonic and non-embryonic stem cells? What are the crucial differences and distinctions we need to make as a society and citizenry?

Stem-cell technologies are some of the newest and fastest developing biotechnologies. Typically, along with genetic engineering and cloning, these technologies constitute the kind of 21st century advances that make this the century of Biology.

A stem cell is a type of cell that is nonspecific in its function; in contrast, for instance, to a heart or brain cell, which is functionally specific. There are two major sources of stem cells: embryonic stem cells and non-embryonic stem cells. Embryonic stem cells are obtained from 5- to 12-day old embryos. Although removal of a stem cell from an embryo kills the embryo, the stem cells are valued for their potential to produce any type of cell. That is, they have high plasticity. Conversely, non-embryonic stem cells are found in large quantities in placenta, umbilical cord blood, amniotic fluid, and in essentially all adult organs or tissues, including bone marrow, fat, kidney, liver, pancreases, intestines, breast, lung, etc. Any of these non-embryonic stem cells have ample plasticity and can give rise to nearly any type of cells, including heart, liver, lung, muscle, etc.

Thus, the heart of the stem-cell controversy centers on the aforementioned fact that the extraction of stem cells from 5- to 12-day embryos kills the embryo. But thats not the only issue: In addition, stem cells derived from an embryonic human may, in turn, reject the person who receives them. This situation is called graft-versus-host-disease (GVHD). The problem can be avoided by producing an embryonic clone of the person needing the stem cells. However, the procedure produces an embryo that is indistinguishable from an embryo from a fertilized egg. This embryonic clone would be destroyed during the stem-cell harvesting required by the therapy. This type of cloning is called therapeutic cloning, since the production of a human baby is not the goal. (Reproductive cloning, producing a cloned human baby, has been universally outlawed.)

Another problem is that the embryonic stem cells can unpredictably cause cancer in the treated patient.

On the other hand, newly developed treatments associated with non-embryonic (adult) stem cells are way ahead of any hoped-for treatments associated with embryonic stem cells. Recent non-embryonic stem-cell therapies include treatments for non-healing bone breaks, healing damaged hearts, regenerating damaged muscles, correcting scoliosis, regenerating knee cartilage, treating thalassemia, osteoarthritis, diabetes, lupus, multiple sclerosis, spinal chord and nerve damage. Treatments to heal conditions associated with almost any organ or tissue are in view. These advances cast serious doubt on the need to develop embryonic stem-cell therapies, especially since embryonic technologies are morally objectionable, given that they require the death of the human embryo.

The use of ones own adult stem cells (autologous stem-cell transplant) is a way to avoid the problems of rejection and of killing human embryos. Also, certain types of adult stem cells (mesenchymal cells) can be harvested from anyone and changed in the lab (transdifferentiated) into a desired cell. In both of these stem-cell applications there are no adverse effects to the donor of the adult stem cells. The non-embryonic stem cells are safely harvested, purified from other cells and/or expanded in culture, and introduced into the patient without rejection. In another process, virtually any adult cell can be harvested from ones own body and treated to become cells capable of producing the needed cell type (induced pluripotent stem cells or iPS). These cells can also be cultured in the lab, and reintroduced into the patient. All of these sources of adult stem cells avoid the problem of having to use patented embryonic stem-cell lines that would be less available to the public.

And yet, the reputed plasticity of the embryonic stem cells continues to make the prospects of doing research on human embryos attractive to researchers who are uninhibited by the prospect of killing human embryos.

It is worth pointing out that, in terms of medical applications and treatments, two major facts are usually left out of these discussions: First, non-embryonic stem-cell treatments have been used to treat tens of thousands of patients, and with dramatic benefits. However, embryonic stem cells have not had one clinical trial with humans. Also, it has been clearly demonstrated that non-embryonic stem cells do not produce cancerous tumors in humans. Whether iPS cells share this non-tumorigenic quality is not yet clear. However, iPS cells have all of the medical application value hoped for in embryonic stem cells.

It must be noted that in a field as rapidly moving as stem-cell research, this situation will likely not be current for long. However, the current progress of stem-cell research as of spring 2009 speaks volumes regarding the effectiveness of non-embryonic vs. embryonic stem-cell research. The promises of embryonic stem-cell researchers are wildly overstated. The claims that embryonic stem-cell therapies will be available in five to 10 years rings hollow.

Aside from these scientific considerations, there are moral-religious matters of obvious concerns to Christians:

Christians committed to the sanctity of human life should look with favor on technologies that preserve and/or improve human life. Consequently, non-embryonic stem-cell advances should be embraced when they: 1) respect the consent and preserve the dignity of the stem-cell donors, 2) enhance the health of the stem-cell recipient, and 3) protect human life at every stage of development. Embryonic stem-cell harvesting remains problematic because the procedure destroys the smallest and most helpless members of the human family: embryos.

In truth, embryonic stem-cell use is being trumped by successful and surprising advances in adult and other non-embryonic stem-cell research. These advances protect the dignity of the donor and recipient while recognizing the value of all humans, regardless of their stage of life, from conception through old age. Hence, all frozen human embryos should be given a chance to be born, not given over to researchers to be destroyed for the sake of a research project.

Dr. Jan Dudt is a professor of biology at Grove City College and fellow for medical ethics with The Center for Vision & Values. He teaches as part of colleges required core course Studies in Science, Faith and Technology wherein students, among other things, study all of the major origins theories and are asked to measure them in the light of biblical authority.

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Crucial Differences Between Non-Embryonic and Embryonic Stem ...

Platelet-Rich Plasma For Arthritis | Dr. Colin MacLeod ND

Platelet-rich plasma (PRP) is a therapy which uses a component of a persons own blood to treat their osteoarthritis. PRP is a safe treatment which often gives significant benefit to people suffering from osteoarthritis including improvements in stiffness, pain and mobility.

PRP injections contain a high concentration of your own platelets. These platelets contain a large amount of growth factors, including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-), insulin-like growth factor (IGF), epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF)1.

Table 1. Growth factors involved in tissue repair2.

These growth factors trigger tissue repair in our natural healing and recovery process. When a high concentration of these growth factors is introduced into the area of an injured or arthritic joint the healing process is jump-started.

Some research has suggested that PRP improves the integrity of the joint cartilage by increasing the amount of cartilage producing cells (chondrocytes) and by decreasing their rate of cell death (apoptosis)3. This would conceivably lead to a larger number of chondrocytes actively producing healthy cartilage within the joint and a healthier joint as a result.

PRP is prepared by drawing and centrifuging a small sample of your own blood on the day of treatment. A centrifuge is a device which rapidly rotates, spinning a blood sample at a high speed causing it to separate into layers based on weight. After centrifugation the blood sample separates into a top layer of plasma which is transparent yellow in color (mostly water with some dissolved proteins) and a bottom thick, red layer (red blood cells). At the junction of the plasma and red blood cell layers sits a dense concentration of platelets. This platelet-rich layer of the plasma is the portion of the blood which is collected and used for injection.

PRP is given by injection into the affected site or the site of injury. For example, in cases of tennis elbow the PRP injection is made at the site of the affected common extensor tendon on the elbow and in plantar fasciitis the injection is given at the site of the damaged plantar fascia insertion on the heel of the foot. In the case of osteoarthritis the injury includes two entire joint surfaces. An osteoarthritic joint is treated by injecting PRP into an affected joint space. Since a joint is a closed compartment the PRP fluid stays within the joint, coating the affected joint surfaces and exerting its effect on them through its rich concentration of growth factors.

Many studies have been performed on PRP injections for osteoarthritis and the results have been near-unanimously positive, showing a reduction in pain and improvement in mobility among the people receiving the treatment. In total, 54 studies have investigated PRP as a treatment for osteoarthritis and all 54 of these studies have found that this treatment was beneficial4-57.

Some research has found that 3 PRP injections, with 1 month between each injection, is more effective and gives longer lasting results than only one or two injections33.

Platelet-rich plasma vs hyaluronic acid

Most PRP for osteoarthritis research has been on the knee. To date 44 studies have examined PRPs effect on knee osteoarthritis while the hip has 4 studies, the temporomandibular joint has 3 studies, the ankle has 2 studies and the thumb has 1 study.

Figure 1. Number of studies (by joint) examining platelet-rich plasma for osteoarthritis. Most research performed on knee joint. Although the studies have yet to be done I have also seen good results with osteoarthritis of other joints including the shoulder, wrist and other hand joints.

PRP injection treatments are quite safe, having very little in the way of reported adverse effects58. While most treatments for pain involve a synthetic medication-based therapy, PRP simply uses a component of a persons blood. PRP therefore carries very little risk of causing an allergic reaction. The most common adverse effect of PRP is discomfort at the site of treatment for 1-3 days. This is a common reaction as the mechanism of action of PRP involves a short-term inflammatory phase after treatment which can contribute to discomfort temporarily. As with any injection there is a small chance of infection. There is also a small chance of allergic reaction to the local anesthetic (numbing agent) which is used at the site of the injection.

PRP treatment can provide lasting results for people with osteoarthritis including reduced pain and improved mobility. Typically 3 treatments will be required to attain maximum benefit from PRP. PRP injections can be done 2-4 weeks apart without issue.

PRP injections are a long-term solution for osteoarthritis. While this treatment gives long term benefit some people may experience discomfort following treatment for 1-3 days. In order to deal with this possible discomfort it is best to reduce physical activity after a PRP injection to avoid additional discomfort of the region which was treated. Applying ice to the affected area will not inhibit the effectiveness of the PRP treatment and may help if the treated area is achy or sore.

The treated body part should be rested on the day of treatment and if discomfort remains then 2-3 days of avoiding heavy activity may be required to assist in recovering. Anti-inflammatories such as aspirin, ibuprofen and naproxen in general should not be taken for 2-7 days after a PRP treatment as they could theoretically dampen its effectiveness. Generally acetaminophen (Tylenol) is preferable to anti-inflammatories in this short term to manage any discomfort or pain which may be present.

People with active cancer or active infection are not candidates for PRP treatment. People with thrombocytopenia (low platelets) and people on blood thinners can have PRP treatment but some changes to the treatment may be required.

Naturopathic Doctor at MacLeod Naturopathic

Dr. Colin is a naturopathic doctor practicing in Upper Tantallon in the Halifax Area. He was born and raised in rural Cape Breton and returned to Nova Scotia to practice after finishing his naturopathic education in Toronto. His practice focuses on pain management and maintaining health through physical activity and diet. He utilizes platelet-rich plasma, neural prolotherapy and acupuncture to keep his patients pain-free so that they can stay physically active, social and healthy.

Last updated October 9, 2018

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Platelet-Rich Plasma For Arthritis | Dr. Colin MacLeod ND

Stem Cell Doctor West Bloomfield MI

Stem Cell Doctor West Bloomfield MI

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Our patients receive the most effective, Stem Cell Doctor West Bloomfield MI, safe, and advanced regenerative stem cell therapy available. Stem Cell Doctor West Bloomfield MI, Our unique umbilical cord stem cell therapy activates the bodys own self-healing mechanisms for cellular/tissue regeneration and repair. Stem Cell Doctor West Bloomfield MI,

Human umbilical cord blood stem cells contain mesenchymal stem cells and garner optimal regenerative results. Stem cell therapy is a safe option and does not require surgery. Patients recover faster and there is less potential for complications. Results have proven to far exceed the common surgery-based autologous procedures. There are no negative side effects and the cells are undifferentiated, therefore the body does not reject them. Umbilical cord stem cells have been used for over thirty years to help reduce the chance of organ transplant rejection.

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