The Goal of Cardiac Stem Cell Therapy at Okyanos
Leslie Miller, M.D., F.A.C.C. and Okyanos Chief Science Officer, describes the goal of treating congestive heart failure and coronary artery disease patients with their own fat-derived stem...
By: Okyanos Heart Institute
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The Goal of Cardiac Stem Cell Therapy at Okyanos - Video
Adult Stem Cell Therapy Today: The Future is Here
Leslie Miller, M.D., F.A.C.C. and Okyanos Chief Science Officer, gives an overview of the benefits of adult stem cell therapy for severe heart disease patients. Okyanos provides Cardiac Cell...
By: Okyanos Heart Institute
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Adult Stem Cell Therapy Today: The Future is Here - Video
Freeport, Grand Bahama (PRWEB) October 02, 2014
Dr. Todd K. Malan, M.D., presented to the Grand Bahama Medical & Dental Association 14th Annual Scientific Educational Conference on the science, safety and efficacy of adipose- (fat) derived stem and regenerative cells (ADRCs) for ischemic heart disease and other unmet healthcare needs.
"It was an honor to participate in this conference with medical leadership that values this technology and works so tirelessly to serve the people of Grand Bahama," said Dr. Todd Malan." It is an opportunity for us to work closely with local doctors to improve the quality and standards of care for all patients."
Dr. Malan explained the interrelationship between tissue ischemia, inflammation, autoimmune response and cell death and how ADRCs have combined mechanisms known to assist in repairing multi-factorial illnesses associated with those issues.
According to Malan,The procedure begins with the extraction of a persons body fat, a process done using advanced water-assisted liposuction technology. The persons own adult stem cells are then separated from the fat tissue using a European Union-approved cell processing device."
Immediately following this, the cardiologist injects these cells into and around the low blood flow regions of the heart via a cathetera protocol which allows for better targeting of the cells to repair damaged heart tissue.
Adult stem cell therapy for heart disease is emerging as a new alternative for patients with severe heart conditions who want to live a normal life but are restricted in activities they can no longer do.
"As a leader in providing cell therapy, Okyanos is very excited to bring this innovative treatment to patients in a near-shore, regulated jurisdiction with a new standard of care, said Matt Feshbach, CEO of Okyanos. We welcome the opportunity to help those patients with limited options a chance to live a normal life.
Offering this minimally invasive adult stem cell treatment in their new cardiac catherization lab, Okyanos is scheduled to open in October in Freeport, Grand Bahama.
About Okyanos Heart Institute: (Oh key AH nos)
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Okyanos Presents the Science, Safety, and Efficacy of Adult Stem Cell Therapy
Tijuana, Mexico (PRWEB) October 01, 2014
On August 15, 2014 Regenerative Medicine Institute, Mexico (RMI) began seeing patients through a new ambulatory clinic. Although RMI has been serving patients at Hospital Angeles in Tijuana since 2009, patients with conditions not requiring a hospital stay are now able to be treated at the new ambulatory clinic, giving them more options in their treatment setting.
When it comes to stem cell treatment for heart disease, there are a number of new players, including Okyanos in the Bahamas. As these exciting new practices get off the ground, RMI continues to grow and build upon expertise gained throughout the past five years.
Physicians at RMI began their practice with the knowledge that adipose-derived adult autologous stem cells had the potential to help the body regenerate. It was with a great deal of excitement that they began to offer the option of adult stem cells to seriously ill patients from around the globe. With board certified specialists taking lead in each and every case, RMI developed 27 disease specific research protocols, submitting them for both IRB and government approval.
Through their experiences, RMI learned that not every condition could be treated as successfully as others. It is important that a patient be able to have confidence in his doctor, said Dr. Javier Lopez, Director of RMI. Our board of directors represents cutting-edge researchers and physicians from around the world. The reason we sought a board with such a strong pedigree is that we wanted to be held to the highest possible standards. When a protocol is successful we want to build upon it. When one does not work well, we seek to learn everything we can from it so that the greatest number of patients will benefit.
After five years of clinical practice and through collaboration with various research institutions, RMI has refined its practice and recognized the value of an ambulatory clinic to further serve its patients. In the new clinic physicians use stem cell therapy to treat type 2 diabetes and immunotherapy for serious conditions such as Alzheimers disease, arthritis, chronic kidney disease, hepatitis, lupus, Lyme disease, multiple sclerosis, and Parkinsons disease.
With a practice that offers services through both an ambulatory clinic as well as the state-of-the-art Hospital Angeles, RMI employs some of the most respected physicians and specialists in their field. Due to the sheer amount of research that has taken place over the course of the last five years, RMI has begun to offer a new and promising immunotherapeutic approach to cancer treatment.
Cancer is not a single disease, but rather a group of more than 100 distinct and different illnesses that all begin with cellular abnormalities. Our proprietary T Cell Modulator is a leucocyte extract whose purpose is to regulate immune function by controlling the production of signaling substances that influence immune cell activity, said Dr. Lopez.
As to the concerns patients may have in regard to receiving medical treatment in a foreign country, Dr. Lopez says, Even though many of us live and work in Tijuana, we understand the concerns of patients who may not be familiar with the city. For that reason, we encourage our patients to fly or drive into San Diego. We pick each patient up and shuttle them the few miles across the border to our clinic or Hospital Angeles. It is a routine trip for us and we have never faced a problem. Our ultimate goal is to keep our patients comfortable.
Dr. Lopez expresses enthusiasm as other programs, like Okyanos, open their doors for the first time. The media shares plenty of stories of international clinics with less-than-honest practices, but there are also amazing medical programs out there, doing the cutting-edge work that will help us get a handle on how most major health issues can be effectively dealt with.
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Stem Cell Treatment for Heart Disease
China tests stem cell therapy for heart disease
Monday marks World Heart Day. One of the most serious conditions is Chronic Heart Disease. It has no cure to date, but in China, scientists are hoping to find one, using stem-cell technology.
By: CCTV America
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China tests stem cell therapy for heart disease - Video
About cell therapy
Cell therapy is a new official direction in medicine, based on the use of regenerative potential of the adult stem cells, aimed at the treatment of a variety of serious diseases, rehabilitation of patients after injuries and fighting with the premature signs of aging. Stem cells are also considered to be the promising biological material for the creation of the prosthetic heart valves, blood vessels, trachea, they are also used as the unique biofiller for the reconstitution of bone defects and other purposes of the plastic and reconstructive surgery.
The scientists explain the regenerative mechanism of action of stem cells both by their ability to transform into the cells of blood, liver, myocardium, bone, cartilage or nervous tissue and thus restore damaged organs and also by the reovery of the functional activity of the other cells (through the so-called paracrine type) by means of the production of a variety of growth factors.
For clinical purposes, in most cases stem cells are obtained from the bone marrow and cord blood, it is also known that the amount of stem cells, sufficient for treatment, can be isolated from the peripheral blood of an adult person, but after pre-stimulation of hematopoiesis. In recent years there is an increasing number of reports worldwide on the clinical application of stem cells, derived from the placenta, adipose tissue, umbilical cord tissue, amniotic fluid, and even pulp of the milk teeth. Depending on the disease, age and condition of the patient, one or another source of stem cells may be preferred. Hematopoietic (blood-forming) stem cells are used for more than 50 years in the treatment of leukemia and lymphomas, and this treatment is commonly known as the bone marrow transplantation, but today hematopoietic stem cells, derived from umbilical cord blood and peripheral blood are more often used in the hematologic clinics of the world. At the same time, for the treatment of traumatic brain and spinal cord injuries, the stimulation of fractures and chronic wounds healing the mesenchymal stem cells are more preferred, being the precursors of the connective tissue. Mesenchymal stem cells are found in big quantity in fatty tissue, placenta, umbilical cord blood, amniotic fluid. Due to the immunosuppressive effects of mesenchymal stem cells, they are also used in the treatment of a variety of autoimmune diseases (multiple sclerosis, ulcerative colitis, Crohns disease, etc.), as well as post-transplantation complications (to prevent the rejection of the transplanted donor organ). For the treatment of cardiovascular diseases, including lower limbs ischemia, the umbilical cord blood is considered to be the most promising, as it contains a special kind of the endothelial progenitor stem cells, which can not be found in any other human tissue.
Cell therapy may be autologous (own cells are used) and allogeneic (donor cells are used). However, it is known that every nucleated cell in the human body has certain immunological characteristics (HLA-phenotype or immune passport), that is why the use of donor stem cells requires immunological compatibility. This fact determines the appropriateness of the banking of the own stem cells, frozen until the person is still young and healthy. In this aspect the human umbilical cord blood has undisputed medical and biological value as the source of several unique lines of stem cells. Collected in the first minutes of life, umbilical cord blood stem cells have the highest potential for proliferation (growth) and directed differentiation.
Stem cell therapy can be applied both intravenously like a drug, and directly into the damaged tissue. In recent years the method of intraosseous transplantation of cord blood stem cells is more widely used, contributing to the more rapid engraftment. Also a method of introducing stem cells directly into the coronary arteries (coronary heart disease, myocardial infarction) was introduced and it is called cellular cardiomyoplasty.
Cell therapy can be carried out both in monotherapy and complementary to the surgical or drug treatment.
Currently stem cells are successfully used in the treatment of about 100 serious diseases, and in some cases this is the only effective treatment.
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Cell therapy - Institute of Cell Therapy - ...
HUNTSVILLE, Ala. (WAAY) -- We hate to see our elderly loved ones start having trouble getting around. The same goes for our pets. They're part of the family too. Now there's a procedure that could help pets across the valley, in just one day.
For Tasha, Wednesday was a big day. The 12 year old black lab has a tough time getting around. She has hip dysplasia and arthritis. But this visit to Whitesburg Animal Hospital, should change that.
"In a week, they're better. Even in the first day or two, you'll see noticeable improvement," says Whitesburg veterinarian Dr. Mark Russell.
The hospital teamed up with MediVet America to offer a one-day stem cell procedure, the first in North Alabama. It can now activate sleeping stem cells in an animal's fat, then inject them right back into the damaged areas.
"The stem cells will repair and regenerate cartilage, tendons, whatever is lacking in that area," says Trey Smith, the Director of Lab Services for MediVet America.
In the past, the cells had to be sent to California to be activated. This quicker procedure has another benefit.
"We've relied on medications to try to control this, and that's pretty much all we had. And you get to a certain point, when the medication doesn't work anymore, and their quality of life is bad. That's not hardly worth it for them. This gives them a whole new option," Dr. Russell says.
"Probably 20 to 25 percent of dogs are arthritic and they're not very good at telling their owner they're hurting," adds Smith.
So, what should you look for?
Russell says, "When your pet starts slowing down, it may not be because they're getting older, it may be because they're hurt."
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Stem cell therapy for pets available in Huntsville
SEATTLE ( TheStreet) -- Seattle Genetics (SGEN) will seek to expand the approved use of its Hodgkin lymphomadrug Adcetris following positive results from a phase III study, the company announced Monday.
In the study (known as AETHERA), treatment with Adcetris in "high risk" Hodgkin lymphomapatients immediately after a stem-cell transplant led to a 43% reduction in the risk of disease progression compared to placebo. The result was statistically significant and met the primary endpoint of the study.The Hodgkin lymphoma patients enrolled in the study were deemed to be "high risk" because they had at least one factorthat made them more susceptible to disease relapse.
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Despite delaying disease progression, treatment with Adcetris did not prolong survival compared to placebo in the phase III study at this analysis, which the company blames partly on placebo patients "crossing over" to receive Adcetris once their disease progressed. Another survival analysis of the study will be conducted in 2016. Adcetris' safety profile was "generally consistent" with previous studies, the company said. No further details were disclosed, pending presentation of the results at a future medical meeting.
Adcetris is already approved to treat more advanced Hodgkin patients who don't respond to a stem cell transplant or who are not eligible for stem cell transplants. Seattle Genetics plans to submit the results from the AETHERA trial to the FDA, seeking approval to expand the drug's use.
Seattle Genetics estimates there are about 1,000 to 1,500 post-transplant Hodgkin lymphoma patients. This represents a modest increase in the number of patients eligible for Adcetris and not as significant a commercial opportunity as treating newly diagnosed Hodgkin lymphoma patients. Studies investigating Adcetris' role in front-line Hodgkin are underway but not yet completed.
Seattle Genetics shares are up 4% to $43 in Monday pre-market trading.
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Seattle Genetics Seeks Expanded Use of Lymphoma Drug Following Study Win
A spice commonly found in curries may boost the brain's ability to heal itself, according to a report in the journal Stem Cell Research and Therapy.
The German study suggests a compound found in turmeric could encourage the growth of nerve cells thought to be part of the brain's repair kit.
Scientists say this work, based in rats, may pave the way for future drugs for strokes and Alzheimer's disease.
But they say more trials are needed to see whether this applies to humans.
Spice injection
Researchers from the Institute of Neuroscience and Medicine in Julich, Germany, studied the effects of aromatic-turmerone - a compound found naturally in turmeric.
Rats were injected with the compound and their brains were then scanned.
Particular parts of the brain, known to be involved in nerve cell growth, were seen to be more active after the aromatic-turmerone infusion.
Scientists say the compound may encourage a proliferation of brain cells.
In a separate part of the trial, researchers bathed rodent neural stem cells (NSCs) in different concentrations of aromatic-tumerone extract.
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Brain Repair 'May Be Boosted By Curry Spice'
Sydney Swans star Adam Goodes is reportedly set to undergo revolutionary stem cell treatment in a bid to prolong his AFL career.
According to News Corp, Goodes has requested the treatment on his troublesome right knee after also undergoing the procedure in January.
He wants to do it again, Swans medico Dr Nathan Gibbs.
Its saved his career. He would have retired a year ago.
Speculation has mounted that Goodes will hang up the boots after Sydneys humiliating loss in the AFL grand final against Hawthorn.
The fire still burns ... It can't help but burn after that loss.
The 34-year-old was among very few Sydney players who played well in the shock defeat.
He hurt his right knee in the grand final 2012 which damaged joint surface, then he damaged the cartilage in the same knee against Port last year, Gibbs said.
Goodes looks shattered after the grand final. Source: Getty
It was terrible because it was the last thing he needed. The surface damage of his knee was extensive, the medial and lateral sides were pretty bad and he just couldnt recover from it.
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Revolutionary treatment to extend Goodes' career?