San Diego Stem Cell Clinic, Telehealth, Now Offering Knee Procedures for Cartilage Restoration

San Diego, California (PRWEB) October 28, 2014

The top stem cell clinic in San Diego, Telehealth, is now offering regenerative medicine procedures for the knee to help restore cartilage and avoid the need for joint replacement. The procedures are outpatient and performed by Board Certified doctors at Telehealth. Call (888) 828-4575 for more information and scheduling.

Hundreds of thousands of knee replacements are performed every year in the US, with most being extremely successful. However, it is a major surgery and there is a chance of complications such as infection or blood clot. Therefore, it is advisable to consider a stem cell procedure for the arthritic knee in an effort to delay or avoid the procedure.

Telehealth provides the procedures with several options, including platelet rich plasma therapy, bone marrow or fat derived stem cells, along with amniotic derived procedures. All of the procedures are outpatient and low risk.

In most cases, the procedures are covered in whole or partly by insurance. Telehealth will perform an insurance verification prior to one's procedure. The Board Certified doctors at the stem cell clinic in San Diego treat patients from a broad area in Southern California. There are several locations including La Jolla, Orange and Upland CA.

In addition to stem cell procedures for knee arthritis, TeleHealth also provides regenerative medicine options for tendon and ligament injuries, sports injuries along with hip, shoulder and ankle arthritis.

For those interested in avoiding knee replacement with a procedure that can potentially preserve or repair arthritic cartilage, call Telehealth at (888) 828-4575 and visit http://stemcelltherapyincalifornia.com/ for more information.

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San Diego Stem Cell Clinic, Telehealth, Now Offering Knee Procedures for Cartilage Restoration

My Pet World: Stem cell treatments show promise for some feline health issues

Q: You recently wrote about stem cell research, and I understand that stem cell therapy is being used to treat inflammatory bowel disease in cats. Do you have more details?

A: The Winn Feline Foundation has funded the research of Dr. Craig Webb and Dr. Tracy Webb of Colorado State University College of Veterinary Medicine to study the use of stem cells to treat inflammatory bowel disease in cats. Early results are promising.

Stem cell research in cats doesn't stop there. Dr. Glenn Olah, president of the Winn Feline Foundation, notes that Winn also funded stem cell studies to treat feline asthma and kidney disease. Results are hopeful, but it's simply too early to offer definitive answers.

"In some ways, stem cell studies in pets are ahead of (those in) people."

Q: About a month ago, I adopted a beautiful Burmese after she romanced me at the shelter. Once we got home, she wanted nothing to do with me. It's not that she isn't friendly. She loves my son and even sleeps with him. When I get up early to feed her, she stays away until I've left the room. My son suggested that the cat harbors resentment toward me because I took her from her cat friends. What can do to improve the situation?

A: "The good news is that it's very unlikely the cat harbors any resentment," said Winn Feline board member and feline veterinarian Dr. Drew Weigner, of Atlanta. "The bad news for you -- but good news for the cat and your son -- is that they developed a fast friendship.

Here are tips that might help the cat warm up to you:

Sit on the floor in an empty room with her. Close the door, but provide an empty box or two for the cat to hop into. Then, simply watch TV, or read a children's story out loud. Cats sometimes like that soft sing-song voice we tend to use when reading children's stories.

Wait until the cat comes to you. It may take several days, but eventually curiosity will out.

Next, take over feeding the cat, even if she waits for you to leave the room to eat.

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My Pet World: Stem cell treatments show promise for some feline health issues

Toxin-producing stem cells fight brain tumors where it matters most

When it comes to new tumor-fighting treatments, its often as much about location, location, location as it is the actual drug interaction. Cytoxin-producing stem cells produced by scientists at Harvard University lodge at the site of brain tumor removal to continually attack remaining tumor cells. As an alternative to drug treatments that can be invasive or ineffective, the researchers saw promising results against glioblastomas, which hold the dubious distinction of being the most common and most fatal brain cancer.

When surgery is performed to remove a brain tumor, tumor cells are left behind. The common course of treatment to eradicate those remaining cells involves inserting a catheter directly into the brain to dispenses drugs which would otherwise not make it through the blood-brain barrier. However, one particular toxin, Pseudomonas exotoxin (PE), while effective and tolerated by humans, has a very short half-life and when washed over the area where the tumor was removed, degrades before significant interaction occurs with the target cells.

The research team under the direction of Khalid Shah instead created stem cells that were capable of independently producing this cytotoxin. Prior to this research, PE and other toxins had been engineered to not enter (and thus subsequently destroy) any human cells they came into contact with. However, Shahs stem cells would need to have this resistance when the toxin was by design already inside the cell.

After genetically constructing a stem cell that produced a toxin that it also could resist, the next design trick involved encapsulating those cells inside a gel matrix that the lab had previously used to test other tumor-fighting techniques. Their previous research found that the matrix kept the cells and resulting toxins in close proximity to the tumor cells.

This cell-doped gel can then be placed within the cavity created when a tumor is removed and could potentially remove the need to insert catheters for recurring drug treatments. To test this technique, mice first were given different strains of glioblastomas, which is important because not all strains respond in the same way to treatments. Researchers then removed the tumors and inserted the stem cell matrix.

When mice treated in this fashion were compared with those who received the same drug via catheter, and those mice who only had surgery, median survival for those three groups fell out significantly in favor of the stem cell group at 79 days versus 48 for those receiving catheter treatment, and 26 for the control. Additionally, no tumors regrew in those mice with the stem cell matrix, a result not seen in the other groups.

The treatment could have some promising applications, such as engineering cells to dispense multiple toxins, or even based directly off the patients tumor. Shah predicts there could be clinical trials for this technique within five years.

The research was originally published in the journal Stem Cells.

Source: Harvard University

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Toxin-producing stem cells fight brain tumors where it matters most

Cellular Dynamics receives contract to make eye cells

Cellular Dynamics International(CDI) is getting a $1.2 million contract from the National Eye Institute, part of the National Institutes of Health, as part of an effort to fight macular degeneration, a condition that leads to loss of vision.

By reprogramming skin and blood samples from patients with age-related macular degeneration, CDI will create induced pluripotent stem cells and will turn them into human retina cells. The cells will be put back into the patient's eyes to treat the disorder.

Ten patients have been chosen for a pilot study of the process by the National Eye Institute, CDI said.

The Madison company said the process, called autologous cellular therapy, will be the first in the U.S. using a patient's own reprogrammed cells.

Publicly traded CDI was founded by UW-Madison stem cell pioneer James Thomson in 2004 and manufactures large quantities of human stem cells for drug discovery, safety screening and for stem cell banks.

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Cellular Dynamics receives contract to make eye cells

World Stem Cells Clinic Team of Doctors and StaffStem Cell …

World Stem Cells Clinic Team

Dr. Ernesto Gutierrez is a published and extensively educated physician. He is a graduate from the Universidad Anhuac Poniente, School of Medicine in Huixquilucan, Mexico and additionally holds a Masters Degree in Aesthetic and Anti-Aging Medicine from the Instituto Mexicano de Medicina Antienvejecimiento y Esttica, Guadalajara, Mexico.

His studies continued, with rotations in both Florida and Las Vegas. One of the significant aspects of Dr. Gutierrezs training background is his postgraduate training in Age Management medicine. His well rounded approach in the area of whole person medicine expands on the teams expertise to address a wide range of medical issues. This affords you the opportunity to maximizing your stem cell therapy and overall health. His specific medical interests include childhood disorders, such as Autistic Spectral disorder, which began during medical training with additional coursework in Prenatal Vigilance and Birth Defects Prevention presented by Laboratorios Silanes Toluca Mexico, 6 years ago. He holds Diplomat status and a Masters degree in Aesthetic and Anti-Aging Medicine. Dr. Gutierrez has spent considerable time in additional training in the US, with two specialty organization and is certified in Age Management Medicine from Cenegenics Medical Institute, Las Vegas, Nevada. He was a collaborator on two published studies including one concerning hematopoetic stem cell transplantation, at the Instituto Nacional de Cancerologia. His bilingual English and Spanish skills, both in medical and conversational applications, are excellent. Dr. Gutierrez has a thorough understanding of both the North and South American medical systems. As a patient you will experience his level of medical practice excellence.

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Dr. Fredy Sansores completed his subspecialty training in hematology at the prestigious Centro Medico Nacional 20 de Noviembre in Mexico City. This institution is one of the most important teaching and research hospitals in the country. It is ranked as one of the most coveted residency positions for postgraduate medical training, in Latin America. His inclination towards hematology started during his specialty training in internal medicine where he was the lead professor for the hematology module in a nation-wide continuing medical education program for general practitioners.

During his residency Dr. Sansores participated in numerous research papers involving bone marrow and autologous stem cell transplantation. This has enabled him to expand and accelerate our development of cutting edge therapeutic research and clinical therapies. The doctor has also participated in cord blood cryobiology which is a perfect complement to our new cryo banking division, for our patients stem cells. Currently, Dr. Sansores is also the lead physician responsible for the blood bank, in Playa del Carmen. This level of laboratory responsibility is a perfect complement to the strict requirements of our cellular facility. We are very fortunate to have Dr. Sansoress experience and expertise in stem cell treatments as part of our team effort to provide the superior quality of care that has distinguished World Stem Cells Clinic as an industry leader, since its inception.

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Dr. Marcial Maciel, MD is an internationally experienced physician with an extensive background in scientific research and applications as well as in clinical patient management. Maintaining a full academic scholarship, Marcial Maciel graduated as one of the top students in his class from one of the currently renowned medical universities in the country, Anhuac University. He graduated with an outstanding performance diploma his final exam of his career. Also, he achieved a high score in his first United States Medial Licensing Examination.

He has worked the intensive care unit at Floyd Medical Center, Rome, GA United States; under supervision and evaluation of Brijh Singh MD and Neurological Surgery Clinical Training, Las Vegas, NV United States; under supervision of Yevgeniy Khavkin MD and Clinical Internship, University of Aachen, Aachen Germany in Anesthesiology, Emergency, Medicine, Neurology, General Surgery and OBGYN. Dr. Marcial Maciel is Fluent Spanish, English, German. Understands French and has publications and presentations on subject such as Restrictive cardiomyopathy as a socio-medical condition, oxygen levels analysis on rats immunized with modified neural peptides with spinal cord lesion, Immunization with neural-derived antigens inhibits lipid peroxidation alter spinal cord injury, factors that influence self medication for respiratory diseases in Caritas Center of Primary Medical Attention and others.

With his years of experience in clinical and research immunology as well as patient management, he is currently working at World Stem Cells Clinic as part of the specialized physicians team and also actively participates in the improvement and design of stem cell research protocols to provide the best care possible to the patients of World Stem Cells Clinic.

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World Stem Cells Clinic Team of Doctors and StaffStem Cell ...

Global Stem Cells Group Announces Launch of Official Regenestem Network Website

MIAMI (PRWEB) October 27, 2014

Global Stem Cells Group has announced the launch of the official Regenestem Network website, dedicated to promoting the worlds largest and most recognizable membership organization of regenerative medicine practitioners. The Regenestem Network was developed to promote the Miami-based companys global expansion program and establish affiliate representatives able to bring stem cell treatments, therapies, training courses and conferences to communities worldwide.

In order to become a part of the Regenestem Network, medical practitioners are required to have more than five years experience in the health care industry that includes experience in regenerative medicine. In return, network physicians are entitled to a myriad of benefits and advantages built into the Regenestem Network membership model, including:

Global Stem Cells Group Founder and CEO Benito Novas says that Regenestem Network members also enjoy royalty-free income by committing to the companys established protocols and proven system for the best patient outcomes. Additional benefits of the Regenestem Network membership model include:

Unlike a typical franchise agreement, if you decide to leave us someday we dont take your company away from you, Novas says. We build high quality partnerships with leading stem cell scientists and physicians around the world by establishing mutually beneficial relationships based on professional respect and collaboration.

For more information on the Regenestem Network, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com, or call 305-224-1858.

About the Global Stem Cells Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.

Global Stem Cells Groups corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCGs six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.

To learn more about Global Stem Cells Group, Inc.s companies and for investor information, visit the Global Stem Cells Group website, email bnovas(at)regenestem(dot)com, or call 305-224-1858.

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Global Stem Cells Group Announces Launch of Official Regenestem Network Website

Stem Cell Treatment Centers | BioRegeneration Integrated …

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The stem cell treatments provided at the BioRegeneration Integrated Medical Centre are there to help you overcome any medical problem you may be experiencing. Located in a beautiful setting, the Stem Cell Treatment Centers are the perfect place to recover from an illness and get back on your feet. We also provide intravenous nutrient therapy, in addition to the stem cell treatments to enhance the speed of recovery. A stem cell treatment has saved many lives in the past, and continues to provide hope to the hopeless.

The treatments offered by the center are truly novel and unlike that which is offered in many countries around the world. They provide many patients with the chance to greatly improve their health in the most unique way possible. Every year stem cell treatments are being approved for more illness. So far there is full approval for most orthopedic cases including arthritis, sports injuries, ligament tears and fracture non-unions. There is also approval for Diabetes, Critical Limb Ischemia, Erectile Dysfunction, Emphysema and Chronic Bronchitis. Many other illnesses are still in the trial phase and the results are encouraging.

Location:

Casa Cassam Villa &

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Stem Cell Treatment Centers | BioRegeneration Integrated ...

Stem Cell Research Center – Rutgers University

Topics Latest Publications Moore, J.C., M.H. Sheldon, and R.P. Hart (2012) Biobanking in the Era of the Stem Cell: A Technical and Operational Guide, Colloquium Series on Stem Cell Biology, Morgan & Claypool Publishers, DOI: 10.4199/C00059ED1V01Y201206SCB002 : 86 pp. Ricupero, C. L., Swerdel, M. R., & Hart, R. P. (2013). Epigenome analysis of pluripotent stem cells. Methods in molecular biology (Clifton, N.J.), 997, 203-16. PubMed Moore, J.C., K. Atze, P. Yeung, A.J. Toro-Ramos, C. Camarillo, K. Thompson, C.L. Ricupero, M. Brenneman, R.I. Cohen and R.P. Hart (2010) Efficient, high-throughput transfection of human embryonic stem cells., Stem Cell Res Ther 1: 23. Abstract | PubMed Lakshmipathy, U., J. Davila and R.P. Hart (2010) miRNA in pluripotent stem cells., Regen Med 5: 545-55. Abstract | PubMed Moore, J.C., S. Sadowy, M. Alikani, A.J. Toro-Ramos, M.R. Swerdel, R.P. Hart and R.I. Cohen (2010) A high-resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines., Stem Cell Res 4: 92-106. Abstract | PubMed Goff, L.A., J. Davila, M.R. Swerdel, J.C. Moore, R.I. Cohen, H. Wu, Y.E. Sun and R.P. Hart (2009) Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors., PLoS One 4: e7192. Abstract | PubMed SCRC Facilities Procedures requiring non-federally funded lab space : Derivation of new ESC lines Working with non-approved lines

With the new NIH Stem Cell Guidelines now in place, there is much less of a restriction on working with NIH-approved stem cell lines in a federally-funded research laboratory. However, there are still some procedures that are not allowed in a federally-funded environment.

Since the SCRC was built without federal funds these procedures may be performed in this laboratory. Prior to planning such projects, please contact Dr. Martin Grumet, director of the SCRC. Your project will need approval from the Rutgers-UMDNJ ESCRO committee before work may begin.

The New Jersey Stem Cell Symposium is held each September at a convenient location in central New Jersey to bring together researchers from academics and industry. The focus is on current stem cell research and novel technologies. Opportunities for New Jersey scientists to present their work will be offered.

The 2013 Symposium will be held at the Bridgewater Marriott on Tuesday, September 24.

The Rutgers Stem Cell Research Center has partnered with the Rutgers University Cell & DNA Repository (RUCDR) to establish the NIMH Stem Cell Center. This new service of the RUCDR will archive source cells for making iPSC, will make iPSC from cells representing mental health disorders, and distribute both types of cells to NIMH-funded researchers.

With support from the New Jersey Commission on Science & Technology, the Rutgers Stem Cell Research Center has hosted several hands-on training courses in stem cell biology. For information on upcoming scheduled courses, please use this link.

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Stem Cell Research Center - Rutgers University

Canadian Stem Cell Experts Gather For Till-McCulloch 2014

The Till & McCulloch 2014 Stem Cell conference gets underway today in Ottawa.

Every year the conference, sponsored by the Stem Cell Network and the Center for the Commercialization of Regenerative Medicine, honors a leading Canadian researcher.

This years winner,Dr. Michael Rudnicki, is Senior Scientist and Director of the Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute.

Rudnickis lab focuses on the role that stem cells play in skeletal muscle regeneration and repair after injury.

To be chosen by your peers to receive the Till & McCulloch Award is a great honour, made finer by the fact that it will take place in my home city of Ottawa, said Dr. Rudnicki in the official press release of the conference released this morning.

Here is the full program of discussions and list of speakers.

One session will focus on current research in blood disorders and how these are making for better outcomes in the clinic. Dr. Guy Sauvageau of University of Montreal, who recently announced the discovery of a new drug to expand the number of usable stem cells in cord blood, will be presenting an overview of his findings.

Diseases and conditions where stem cell treatment is promising or emerging. (See Wikipedia:Stem cell#Treatments). Bone marrow transplantation is, as of 2009, the only established use of stem cells. Model: Mikael Hggstrm. To discuss image, please see Template talk:Hggstrm diagrams (Photo credit: Wikipedia)

Also on the agenda for discussion and debate will be the societal impact of stem cell research, including approaches in moving research towards clinical treatments for patients and theinvestigation of cancer stem cells and their role in the formation of tumors and their recurrence after treatments.

On the education and outreach side, the Stem Cell Network also plans t0 highlight its recent foray into online video, with its Stem Cell Shorts program, which can be accessed on Vimeo. You can follow the conference on Twitter via#TMM2014.

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Canadian Stem Cell Experts Gather For Till-McCulloch 2014

Team proposes benchmark to better replicate natural stem cell development in the laboratory environment

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In a study that will provide the foundation for scientists to better replicate natural stem cell development in an artificial environment, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Guoping Fan, professor of human genetics, have established a benchmarking standard to assess how culture conditions used to procure stem cells in the lab compare to those found in the human embryo.

The study was published online ahead of print in the journal Cell Stem Cell.

Pluripotent stem cells (PSCs) are cells that can transform into almost any cell in the human body. Scientists have long cultured PSCs in the laboratory (in vitro) using many different methods and under a variety of conditions. Though it has been known that culture techniques can affect what kind of cells PSCs eventually become, no "gold standard" has yet been established to help scientists determine how the artificial environment can better replicate that found in a natural state (in vivo).

Dr. Kevin Huang, postdoctoral fellow in the lab of Dr. Fan and a lead author of the study, analyzed data from multiple existing research studies conducted over the past year. These previously published studies used different culture methods newly developed in vitro in the hopes of coaxing human stem cells into a type of pluripotency that is in a primitive or ground-zero state.

Utilizing recently-published gene expression profiles of human preimplantation embryos as the benchmark to analyze the data, Dr. Huang and colleagues found that culture conditions do affect how genes are expressed in PSCs, and that the newer generation culture methods appear to better resemble those found in the natural environment of developing embryos. This work lays the foundation on the adoption of standardized protocol amongst the scientific community.

"By making an objective assessment of these different laboratory techniques, we found that some may have more of an edge over others in better replicating a natural state," said Dr. Huang. "When you have culture conditions that more consistently match a non-artificial environment, you have the potential for a much better reflection of what is going on in actual human development."

With these findings, Dr. Fan's lab hopes to encourage further investigation into other cell characteristics and molecular markers that determine the effectiveness of culture conditions on the proliferation and self-renewal of PSCs.

"We hope this work will help the research community to reach a consensus to quality-control human pluripotent stem cells," said Dr. Fan.

Explore further: Technique to make human embryonic stem cells more closely resemble true epiblast cells

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Team proposes benchmark to better replicate natural stem cell development in the laboratory environment