Stem Cell Clinic

Beverly Hills Orthopedic Institute Now Offering Stem Cell Procedures for Rotator Cuff Injuries with Double Board …

By Stem Cell Doctors

Beverly Hills, California (PRWEB) April 21, 2014

Beverly Hills Orthopedic Institute is now offering stem cell procedures for rotator cuff injuries including tendonitis and tears. The procedures have been helping patients avoid the need for surgery and are provided by a Double Board Certified orthopedic doctor, Dr. Raj. Call (310) 438-5343 for more information and scheduling.

Shoulder pain due to rotator cuff tendonitis and tears affects millions of Americans. it can lead to considerable disability. For an individual who likes to participate in sports activities, a rotator cuff injury can make it impossible. If surgery is undertaken, it can lead to months of rehabilitation and have potential complications.

Dr. Raj is a Double Board Certified Beverly Hills orthopedic surgeon who has been a pioneer in the usage of stem cell procedures for shoulder conditions. This includes using amniotic derived stem cell injections, which contain a lot of regenerative qualities. These include a high concentration of stem cells, growth factors, antimicrobial properties and hyaluronic acid. All of these components assist with repair and regeneration of damaged rotator cuff tissue, and frequently allow the patient to obtain pain relief and avoid surgery.

In addition, Dr. Raj also utilizes bone marrow derived stem cell injections. This procedure involves a short harvesting of bone marrow from the hip area, with immediate processing to concentrate stem cells and injection into the affected area at the same setting. Platelet rich plasma therapy is also offered as well.

Several times, Dr. Raj has been named one of the top orthopedic doctors in Los Angeles. He is also an ABC News Medical Correspondent and a WebMD Medical Expert. For more information and scheduling for stem cells for rotator cuff tears and tendonitis, call (310) 438-5343.

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Beverly Hills Orthopedic Institute Now Offering Stem Cell Procedures for Rotator Cuff Injuries with Double Board ...

Stem Cells: Get Facts on Uses, Types, and Therapies

By Stem Cell Medicine

Stem cell facts Stem cells are primitive cells that have the potential to differentiate, or develop into, a variety of specific cell types. There are different types of stem cells based upon their origin and ability to differentiate. Bone marrow transplantation is an example of a stem cell therapy that is in widespread use. Research is underway to determine whether stem cell therapy may be useful in treating a wide variety of conditions, including diabetes, heart disease, Parkinson's disease, and spinal cord injury. What are stem cells?

Stem cells are cells that have the potential to develop into many different or specialized cell types. Stem cells can be thought of as primitive, "unspecialized" cells that are able to divide and become specialized cells of the body such as liver cells, muscle cells, blood cells, and other cells with specific functions. Stem cells are referred to as "undifferentiated" cells because they have not yet committed to a developmental path that will form a specific tissue or organ. The process of changing into a specific cell type is known as differentiation. In some areas of the body, stem cells divide regularly to renew and repair the existing tissue. The bone marrow and gastrointestinal tract are examples areas in which stem cells function to renew and repair tissue.

The best and most readily understood example of a stem cell in humans is that of the fertilized egg, or zygote. A zygote is a single cell that is formed by the union of a sperm and ovum. The sperm and the ovum each carry half of the genetic material required to form a new individual. Once that single cell or zygote starts dividing, it is known as an embryo. One cell becomes two, two become four, four become eight, eight to sixteen, and so on; doubling rapidly until it ultimately creates the entire sophisticated organism. That organism, a person, is an immensely complicated structure consisting of many, many, billions of cells with functions as diverse as those of your eyes, your heart, your immune system, the color of your skin, your brain, etc. All of the specialized cells that make up these body systems are descendants of the original zygote, a stem cell with the potential to ultimately develop into all kinds of body cells. The cells of a zygote are totipotent, meaning that they have the capacity to develop into any type of cell in the body.

The process by which stem cells commit to become differentiated, or specialized, cells is complex and involves the regulation of gene expression. Research is ongoing to further understand the molecular events and controls necessary for stem cells to become specialized cell types.

Medically Reviewed by a Doctor on 1/23/2014

Stem Cells - Experience Question: Please describe your experience with stem cells.

Stem Cells - Umbilical Cord Question: Have you had your child's umbilical cord blood banked? Please share your experience.

Stem Cells - Available Therapies Question: Did you or someone you know have stem cell therapy? Please discuss your experience.

Medical Author:

Melissa Conrad Stppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

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Stem Cells: Get Facts on Uses, Types, and Therapies

Stanford scientists identify source of most cases of invasive bladder cancer

By Stem Cell Medical Center

PUBLIC RELEASE DATE:

20-Apr-2014

Contact: Krista Conger kristac@stanford.edu 650-725-5371 Stanford University Medical Center

STANFORD, Calif. A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.

Their study, conducted in mice, is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers. It's also the first to show that most bladder cancers and their associated precancerous lesions arise from just one cell, and explains why many human bladder cancers recur after therapy.

"We've learned that, at an intermediate stage during cancer progression, a single cancer stem cell and its progeny can quickly and completely replace the entire bladder lining," said Philip Beachy, PhD, professor of biochemistry and of developmental biology. "All of these cells have already taken several steps along the path to becoming an aggressive tumor. Thus, even when invasive carcinomas are successfully removed through surgery, this corrupted lining remains in place and has a high probability of progression."

Although the cancer stem cells, and the precancerous lesions they form in the bladder lining, universally express an important signaling protein called sonic hedgehog, the cells of subsequent invasive cancers invariably do not a critical switch that appears vital for invasion and metastasis. This switch may explain certain confusing aspects of previous studies on the cellular origins of bladder cancer in humans. It also pinpoints a possible weak link in cancer progression that could be targeted by therapies.

"This could be a game changer in terms of therapeutic and diagnostic approaches," said Michael Hsieh, MD, PhD, assistant professor of urology and a co-author of the study. "Until now, it's not been clear whether bladder cancers arise as the result of cancerous mutations in many cells in the bladder lining as the result of ongoing exposure to toxins excreted in the urine, or if it's due instead to a defect in one cell or cell type. If we can better understand how bladder cancers begin and progress, we may be able to target the cancer stem cell, or to find molecular markers to enable earlier diagnosis and disease monitoring."

Beachy is the senior author of the study, which will be published online April 20 in Nature Cell Biology. He is the Ernest and Amelia Gallo Professor in the School of Medicine and a member of the Stanford Cancer Institute and the Stanford Institute for Stem Cell Biology and Regenerative Medicine. He is also a Howard Hughes Medical Institute investigator. Kunyoo Shin, PhD, an instructor at the institute, is the lead author.

Bladder cancer is the fourth most common cancer in men and the ninth most common in women. Smoking is a significant risk factor. There are two main types of the disease: one that invades the muscle around the bladder and metastasizes to other organs, and another that remains confined to the bladder lining. Unlike the more-treatable, noninvasive cancer which comprises about 70 percent of bladder cancers the invasive form is largely incurable. It is expensive and difficult to treat, and the high likelihood of recurrence requires ongoing monitoring after treatment.

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Stanford scientists identify source of most cases of invasive bladder cancer

Umbilical cord blood transplants become standard

By Stem Cell Medical Center

Sarah and Marc discovered that in the Philadelphia area, even if parents realized umbilical cords were more than just waste products of childbirth, there was no easy way to donate the tissue. So they established the Mason Shaffer Foundation to change that.

This month, Temple University Hospital launched a program in collaboration with the foundation and the New Jersey Cord Blood Bank to educate expectant parents and enable them to donate in a convenient way - at no charge to them or Temple. The foundation provides the educational material, and the cord-blood bank covers the collection costs, which are offset by health insurance reimbursement for transplants.

Three years ago, Lankenau Medical Center in Wynnewood became the foundation's first cord-blood donation center.

Temple, however, is expected to help fill the desperate need for a more racially diverse cord-blood stockpile. That need was recognized by the federal Stem Cell Therapeutic and Research Act of 2005, which included funding that will help underwrite the first year of Temple's program.

Of the 3,200 babies delivered at Temple each year, 65 percent are African American, and 30 percent are Hispanic.

"Ethnically diverse groups are underrepresented as cord-blood donors and have a lower chance of finding a matched donor," said Dimitrios Mastrogiannis, Temple's director of maternal fetal medicine.

"Our biggest challenge is building diversity," echoed Roger Mrowiec, scientific director of Community Blood Services in Montvale, N.J., which runs the New Jersey Cord Blood Bank. "A Caucasian has about a 95 percent chance of finding a match. For Hispanics, that falls to 70 percent, and for African Americans, it's only 60 percent."

Mrowiec spoke at a Temple news conference where the grown-ups were happily upstaged by the foundation's eponymous poster boy. Although Mason is small for his age and blind in his left eye, his transplant cured his disease: malignant infantile osteopetrosis.

"Do you know why we're here?" his mother asked him.

"Because I got cells that fixed my bones," the precocious preschooler piped up.

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Umbilical cord blood transplants become standard

Colorado Clinic Now Accepting New Pain Management Patients at Three Locations in Northern Colorado Including Boulder …

By Stem Cell Clinic

Greeley, Colorado (PRWEB) April 21, 2014

The top pain management clinics in Northern Colorado, Colorado Clinic, now are accepting patients at three locations in Boulder, Greeley and Loveland. Treatment is provided by a Double Board Certified pain management doctor with most insurance being accepted.

Colorado Clinic offers a number of services dedicated for pain relief. This includes sports medicine treatment, medical and interventional pain therapies and hormone replacement therapy. With the various treatments, there are over 50 therapy options to customize for patient needs.

In addition to conventional pain treatments such as epidural injections and pain medication, Colorado Clinic also provides several cutting edge options. This includes regenerative medicine with stem cell procedures and platelet rich plasma therapy. Also, radiofrequency ablation, spinal cord stimulator implants, kyphoplasty and medial branch blocks are offered as well.

All types of acute and chronic pain conditions are treated at each location including back and neck pain, arthritis, sciatica, degenerative disc disease, fibromyalgia, RSD, headaches and much more.

All of the Colorado Clinic locations accept most insurances including Medicare, PPO's, some HMO's, Colorado Workers Compensation, Personal Injury Liens and self pay as well. To initiate treatment, call the closest location: Loveland Pain Management (970) 221-9451 Boulder Pain Management (303) 444-4141 Greeley Pain Management (970) 396-6994

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stem cell therapy treatment for Global Developmental Delay with Severe Mental Retardation – Video

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stem cell therapy treatment for Global Developmental Delay with Severe Mental Retardation
improvement seen in just 3 months after stem cell therapy treatment for Global Developmental Delay with Severe Mental Retardation by dr alok sharma, mumbai, ...

By: Neurogen Brain and Spine Institute

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stem cell therapy treatment for Global Developmental Delay with Severe Mental Retardation - Video

stem cell therapy treatment for cerebral palsy with mental retardation with low vision by dr alok – Video

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stem cell therapy treatment for cerebral palsy with mental retardation with low vision by dr alok
improvement seen in just 3 months after stem cell therapy treatment for cerebral palsy with mental retardation with low vision by dr alok sharma, mumbai, ind...

By: Neurogen Brain and Spine Institute

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stem cell therapy treatment for cerebral palsy with mental retardation with low vision by dr alok - Video

Cancer Stem Cells Linked to Drug Resistance

By Stem Cell Treatment

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Newswise Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

The findings, published in the April 20, 2014 online issue of Nature Cell Biology, may point to new therapeutic opportunities for reversing drug resistance in a range of cancers, including those in the lung, pancreas and breast.

There are a number of drugs that patients respond to during their initial cancer treatment, but relapse occurs when cancer cells become drug-resistant, said David Cheresh, PhD, Distinguished Professor of Pathology and UC San Diego Moores Cancer Center associate director for Innovation and Industry Alliances. We looked at the cells before and after they became resistant and asked, What has changed in the cells?

Cheresh and colleagues investigated how tumor cells become resistant to drugs like erlotinib or lapatinib, known as receptor tyrosine kinase inhibitors and commonly used in standard cancer therapies. They found that as drug resistance occurs, tumor cells acquire stem cell-like properties that give them the capacity to survive throughout the body and essentially ignore the drugs.

Specifically, the scientists delineated the molecular pathway that facilitates both cancer stemness and drug resistance, and were able to identify existing drugs that exploit this pathway. These drugs not only reverse stem cell-like properties of tumors, but also appear to re-sensitize tumors to drugs that the cancer cells had developed resistance to.

The good news is that weve uncovered a previously undefined pathway that the tumor cells use to transform into cancer stem cells and that enable tumors to become resistant to commonly used cancer drugs, said Cheresh.

Based on these findings, Hatim Husain, MD, an assistant professor who treats lung and brain cancer patients at Moores Cancer Center, has designed a clinical trial to attack this pathway in patients whose tumors are drug-resistant. The trial will be open to patients with lung cancer who have experienced cancer progression and drug resistance to erlotinib. It is expected to begin in the next year.

Resistance builds to targeted therapies against cancer, and we have furthered our understanding of the mechanisms by which that happens, said Husain. Based on these research findings we now better understand how to exploit the Achilles heel of these drug-resistant tumors. Treatments will evolve into combinational therapies where one may keep the disease under control and delay resistance mechanisms from occurring for extended periods of time.

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Cancer Stem Cells Linked to Drug Resistance

Top Phoenix Foot and Ankle Specialist, Valley Foot Surgeons, Now Offering Stem Cell Procedures for Healing Diabetic …

By Stem Cell Treatment

Phoenix, Arizona (PRWEB) April 21, 2014

The top foot and ankle specialists in Arizona at Valley Foot Surgeons are now offering stem cell treatments for diabetic wounds. The treatments may propel these difficult wounds to heal in a much shorter time frame than they would without regenerative medicine therapy. The stem cell doctor is a four-time Phoenix Magazine Top Doc Winner; call (480) 994-5977 for more information and scheduling.

With up to a third of individuals suffering from diabetes (or pre-diabetes), wounds and ulcers are becoming more common all the time in the foot and ankle area. Due to the immunocompromised state of diabetics, it can be extremely difficult for the human body to naturally heal these wounds. Sometimes, they persist for years, become infected, and may lead to an eventual need for an amputation.

At Valley Foot Surgeons, Phoenix Top Doc Richard Jacoby is now offering stem cell treatments for diabetic wounds. These treatments are performed as an outpatient and involve subcutaneous injections of amniotic derived stem cell material around the wound.

The procedure offers several benefits in addition to a hefty concentration of stem cells. The material is immunologically privileged and does not cause a rejection reaction. It is processed from an FDA regulated lab.

The amniotic derived stem cells assists with the creation of new blood vessels to help heal the wounds and also contains a significant amount of growth factors. The stem cell material also has antimicrobial properties, helping avoid infection.

Along with the stem cell procedures, Valley Foot Surgeons offers laser treatment simultaneously which further helps with the healing process. With approximately 100 stem cell procedures performed so far for diabetic wounds, the outcomes have been nothing short of incredible.

Wounds have been healing, and much faster than with conventional methods. For more information and treatment with the top foot and ankle stem cell doctor in Phoenix and Scottsdale, call (480) 420-3499.

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Top Phoenix Foot and Ankle Specialist, Valley Foot Surgeons, Now Offering Stem Cell Procedures for Healing Diabetic ...

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