Stem Cell Therapeutics Adopts Shareholder Rights Plan

TORONTO, ONTARIO--(Marketwired - Sep 17, 2013) - Stem Cell Therapeutics Corp. (TSX VENTURE:SSS)(SCTPF), a biopharmaceutical company developing cancer stem cell-related therapeutics, today announces that it has adopted a shareholder rights plan (the "Plan") effective September 16, 2013. The Company will be seeking shareholder approval of the Plan at its next annual general and special meeting of shareholders.

The Plan is designed to ensure the fair and equal treatment of shareholders in connection with any take-over bid for outstanding common shares of the Company. The Plan is not intended to prevent or deter take-over bids that offer fair treatment and value to shareholders, but is designed to encourage offers that represent fair value to all shareholders. The Plan seeks to provide shareholders with adequate time to properly assess a take-over bid without undue pressure. It also provides the Board of Directors with adequate time to fully assess an unsolicited take-over bid, to allow competing bids to emerge, and, if applicable, to explore other alternatives to the take-over bid to maximize shareholder value.

Under the terms of the Plan, one right will be issued by the Company for each outstanding Stem Cell Therapeutics ("SCT") common share at the close of business on September 16, 2013, and for each SCT common share issued in the future (subject to the terms of the Plan). The rights issued under the Plan become exercisable only if a person acquires or announces its intention to acquire 20% or more of the common shares of the Company without complying with the "Permitted Bid" provisions of the Plan or without the approval of SCT's Board of Directors.

Permitted Bids must be made to all holders of SCT common shares by way of a take-over bid circular prepared in compliance with applicable securities laws and, among other things, must be open for acceptance for a minimum of 60 days. If at the end of 60 days at least 50% of the outstanding common shares other than those owned by the offeror and certain related parties have been tendered and not withdrawn, the bidder may take-up and pay for the shares but must extend the bid for a further 10 days to allow other shareholders to tender to the bid.

If a take-over bid does not meet the Permitted Bid requirements of the Plan, the rights will entitle shareholders, excluding the shareholder or shareholders making the take-over bid, to purchase additional common shares of the Company at a substantial discount to the market price of the common shares at that time.

The Company is not adopting a Plan in response to any proposal to acquire control of the Company. The Plan is similar to plans adopted by other Canadian companies and ratified by their shareholders.

Although effective as of September 16, 2013, the Plan will be presented for ratification by the Company's shareholders at the next annual general and special meeting. If ratified by the shareholders, the Plan will have an initial term of 3 years.

About Stem Cell Therapeutics:

Stem Cell Therapeutics Corp. is a biopharmaceutical company advancing cancer stem cell discoveries into novel and innovative cancer therapies. Building on over half a century of leading and groundbreaking Canadian stem cell research, the company is supported by established links to a group of Toronto academic research institutes and cancer treatment centers, representing one of the world's most acclaimed cancer research hubs. The Company has two premier preclinical programs, SIRPaFc and a CD200 monoclonal antibody ("mAb"), which target two key immunoregulatory pathways that tumor cells exploit to evade the host immune system. SIRPaFc is an antibody-like fusion protein that blocks the activity of CD47, a molecule that is upregulated on cancer stem cells in AML and several other tumors. The CD200 mAb is a fully human monoclonal antibody that blocks the activity of CD200, an immunosuppressive molecule that is overexpressed by many hematopoietic and solid tumors. SCT's clinical stage programs include the recently in-licensed program focused on the structure of tigecycline, which is currently being evaluated in a multi-centre Phase I study in patients with acute myeloid leukemia ("AML"), as well as TTI-1612, a non-oncology asset that recently completed dosing in a 28-patient Phase I trial in interstitial cystitis ("IC") patients. For more information, visit http://www.stemcellthera.com.

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Stem Cell Therapeutics Adopts Shareholder Rights Plan


How Prolotherapy, PRP, Stem-Cell Therapy Work - Part 3 of 3 (8-13-13)
Jeff Ericksen, MD, an expert in Regenerative Medicine at the Kaplan Center for Integrative Medicine in McLean, Virginia, describes the effectiveness of using...

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Stem-cell therapy puts local vet on cutting edge

RICHMOND When most people think of stem-cell therapy, they think of cutting-edge medicine human medicine, that is.

What many dont realize is that the technology can be, and is, applied to our four-legged friends as well.

Jim Martin, DVM, a veterinarian who owns and operates four area animal care facilities, including the Waco Animal Hospital, has been using stem-cell therapy to help dogs, mainly with mobility problems, such as arthritis, joint pain and tendon and ligament damage.

The therapy can provide canine patients with renewed energy and freedom of movement.

Martin, associates, and staff members, have been using the procedure on dogs for about a year, with considerable success.

In Kentucky the use of stem-cell therapy has been mainly for horses, Martin explained, but added it works on canines as well.

The procedure doesnt come cheap. Martin said the cost ranges from about $1,800 to $2,200. That includes pre-testing to determine if the dog is a good candidate for the procedure, along with surgical anesthetic and other services necessary to complete the procedure.

Because the stem cells that are injected come from the animals own body, the risk of rejection or reaction is minimal.

The procedures are done in Martins Advanced Animal Care in Richmond, Central Kentuckys only full-service 24-hour-a-day animal hospital. He said a portion of that facility is dedicated to a care center, which treats animals with chronic conditions using not only stem-cell therapy, but also joint injections, laser therapy and even acupuncture.

The facility was the first in the area to offer stem-cell therapy, and Martin said it is the only one he knows of that offers the complete procedure, from the extraction of the stem cells to their implantation.

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Stem-cell therapy puts local vet on cutting edge

Fake Brownsville doctor arrested in stem cell scheme

BROWNSVILLE Federal authorities say a man who posed as a doctor was part of a scheme that used stem cells from the umbilical cords of women at a border maternity clinic to prey on the hopes of patients with incurable diseases.

A 19-page indictment unsealed this week accuses Francisco Dr. Frank Morales, 52, of Brownsville and co-defendants including the owner of a maternity clinic in Del Rio and a researcher in South Carolina of netting at least $1.5 million from procedures Morales performed in Mexico on patients he met in the United States.

Birth mothers at the Maternity Care Clinic were told their umbilical cords were being donated to a research facility.

Instead, they were sent to the researcher to extract stem cells that were sold to Global Laboratories, LLC, in Scottsdale, Ariz., which then sold them to Morales for his unauthorized procedures, the indictment alleges.

Customs and Border Protection officers arrested Morales Dec. 22 in Brownsville. He is to be arraigned in Houston, where the case is pending. Court records show he waived his right to a court-appointed attorney.

Clinic owner and licensed midwife Alberto Ramon, 48, of Del Rio, and researcher Vincent Dammai, 40, of Mount Pleasant, S.C., were arrested Tuesday. A warrant was also issued for Lawrence Stowe, 58, of Dallas, who has been charged in relation to the case and is considered a fugitive.

According to the National Institutes on Health, stem cells are unspecialized cells that can renew themselves and as such hold the promise of repairing or replacing worn-out or damaged tissue. But the research is young, and the U.S. Food and Drug Administration has not approved any stem cell therapies.

The indictment demonstrates the commitment of the FDA to protect the American public from the harms inherent in being exposed to unapproved new drugs, FDA Special Agent in Charge Patrick J. Holland said in a news release announcing the indictment Wednesday. The FDA will continue to aggressively pursue perpetrators of such acts and ensure they are punished to the full extent of the law.

Morales traveled the United States representing himself as an expert on stem cells derived from umbilical cord blood, falsely claiming he was affiliated with stem cell research at Duke, Harvard, and UCLA.

He told one patient, identified in court papers as M.E., that his treatment would drastically improve her symptoms from multiple sclerosis.

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Fake Brownsville doctor arrested in stem cell scheme

Southern California Medical Practice, TeleHealth, Now Offering Bone Marrow Derived Stem Cell Injections

Orange County, CA (PRWEB) September 16, 2013

The premier stem cell clinic in California, TeleHealth, is now offering bone marrow derived stem cell injections for numerous musculoskeletal conditions. The stem cell therapy is typically covered by insurance and is an excellent treatment for conditions such as degenerative arthritis, rotator cuff tendonitis, achilles tendonitis, tennis elbow and much more. For more information and scheduling, call (888) 828-4575.

TeleHealth offers treatment that is cutting edge and revolutionary. When it comes to regenerative medicine, bone marrow stem cell injections are excellent because they are outpatient, low risk and showing effective results. Being covered by insurance makes them additionally on the cutting edge at TeleHealth.

Stem cell therapy is the latest option for degenerative arthritis of the knees, shoulders, hips, ankles and more. Most treatments for arthritis until now have included excellent pain relief methods such as cortisone. However, the treatment has not altered the course of the disease, but simply acted as a "band aid" for pain relief. The bone marrow derived stem cell treatment has the potential to repair and regenerate arthritic joints.

Along with bone marrow derived injections, TeleHealth also offers fat derived stem cell injections along with platelet rich plasma therapy (PRP). These treatments have been revolutionary for pain relief and altering the course of the condition such as with tennis elbow, known as lateral epicondylitis. Most patients are able to avoid surgery and obtain pain relief.

To schedule with TeleHealth for treatments with bone marrow derived stem cell injections, call (888) 828-4575.

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Southern California Medical Practice, TeleHealth, Now Offering Bone Marrow Derived Stem Cell Injections

UC Davis stem cell researcher warns consumers to beware of unproven or dangerous stem cell treatments

In his day job, UC Davis scientist Paul Knoepfler probes the inner workings of stem cells and cancer cells and what makes them behave the way they do.

On the side, the father of three daughters blogs about costly, unproven stem cell treatments and provides guidance for those seeking experimental therapies.

Knoepfler is a rare stem cell researcher who regularly explores the most problematic aspects of stem cell therapies on the Internet in full public gaze. He considers himself an advocate for patients as well as a scientist, having survived an aggressive form of prostate cancer at the age of 42.

Now 46, Knoepfler began his blog in 2010, shortly after his cancer was diagnosed. His blogging has encountered resistance from some colleagues, who are uncomfortable with such public endeavors. But he has polished and expanded the blog to the point that it has received international recognition. He will receive an award in December at the World Stem Cell Summit in San Diego for his advocacy efforts.

This month he moved beyond cyberspace and published Stem Cells: An Insiders Guide (World Scientific Publishing). The book covers stem cells from A to Z and is aimed at the general reader, especially people considering stem cell therapy for themselves, a family member or friend.

The book comes during what has been described by Christopher Scott, a senior research scholar at Stanford University, as an epidemic of transplant clinics offering so-called cures and therapies both here and abroad. The international stem cell medical tourism business, widely promoted on the Internet, is taking in roughly $1 billion annually, according to an estimate in Stanford Medicine, a publication of the Stanford medical school.

Knoepfler is a believer in the potential and power of stem cells. But he says that some of the dubious stem cell treatments now being offered have resulted in deaths and injuries. Other unpleasant issues arise as well in stem cell research, including the tendency of some stem cells to generate cancer cells, and Knoepfler wants to talk about them.

Too often in the academic section of the stem cell field, people pussyfoot around the most important issues or do not even dare talk about them at all, says Knoepfler.

He is not on some crusade to dissuade people from getting risky stem cell procedures, but says safety and training need to be encouraged. Reckless behavior endangers the entire field, he says.

There is no better illustration of the risks of unlicensed stem cell treatments administered by untrained doctors than the recently reported case of a woman who received a stem cell facelift, only to have bone grow in her eye, he said, referring to a Scientific American report involving a Beverly Hills clinic.

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UC Davis stem cell researcher warns consumers to beware of unproven or dangerous stem cell treatments

Southern California Dermatologist Dr. Tess Mauricio: Regenerative Stem Cell Therapy w/Patient Marie – Video


Southern California Dermatologist Dr. Tess Mauricio: Regenerative Stem Cell Therapy w/Patient Marie
America #39;s Favorite Dermatologist, Dr. Tess Mauricio, talks Regenerative Stem Cell Therapy with her patient Marie, who is over 50 and now running Marathons! D...

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Southern California Dermatologist Dr. Tess Mauricio: Regenerative Stem Cell Therapy w/Patient Marie - Video

Orange County Regenerative Medicine Clinic, TeleHealth, Now Offering PRP Therapy Covered by Insurance

Orange, CA (PRWEB) September 11, 2013

The top stem cell therapy clinic in Orange County, TeleHealth, is now offering PRP therapy for degenerative arthritis and soft tissue injuries. The treatment is covered by insurance and represents an excellent method of repairing and regenerating injured tissue rather than simply masking pain. For more information and scheduling, call (888) 828-4575.

PRP therapy has recently become extremely popular in orthopedics and pain management due to multiple studies showing its benefit. One of these studies out of Hospital for Special Surgery showed the treatment relieved knee pain long term from degenerative arthritis and also helped preserve knee cartilage.

TeleHealth offers platelet rich plasma therapy as an outpatient service, and the stem cell therapy clinic accepts most major medical insurances along with Medicare, Workers Compensation and Personal Injury liens. The PRP therapy has very low risk because it involves taking blood from the patient, processing it, and then injecting it into the problem area. The PRP then calls in the body's stem cells for repair and regeneration.

In addition to PRP therapy, TeleHealth also offers stem cell injection therapy with bone marrow derived stem cell injection treatment and fat derived as well. These treatments are also performed as an outpatient and involve utilizing a patient's own tissue so the risks are very low and there are no ethical concerns.

For those interested in receiving platelet rich plasma therapy for degenerative arthritis or soft tissue injury covered by insurance, call (888) 828-4575.

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Orange County Regenerative Medicine Clinic, TeleHealth, Now Offering PRP Therapy Covered by Insurance

The Arrow Group of Animal Hospitals in Central Arizona Partners with Vet-Stem, Inc. to Bring Stem Cell Therapy to …

Poway, California (PRWEB) September 12, 2013

The Arrow Group of Animal Hospitals, out of Glendale, Arizona and their 17 Phoenix Metro area veterinary hospitals have partnered with California based Vet-Stem, Inc., the leading Regenerative Veterinary Medicine company, to bring stem cell therapy to their patients. Dogs that are suffering pain or inflammation from osteoarthritis or polyarthritis, joint or ligament issues, or muscle injuries, can now receive stem cell therapy.

The Arrow Group of Animal Hospitals hosted Vet-Stems Corey Orava, DVM for a week of training sessions to help all of their staff learn the ins and outs of stem cell therapy. Veterinarians and technicians benefited from hands-on labs and a continuing education course that will help them bring the best care to their patients and pet owners. Under the mentorship of Dr. Orava Dobson Ranch Animal Hospital, Fletcher Heights Animal Hospital, Surprise Animal Hospital and Animal Hospital at Anthem were able to perform their debut stem cell therapy cases during their initial week of offering the new service.

The Arrow Group of Animal Hospitals is a co-operative group of 17 individual small animal hospitals around the valley that are proud to offer the highest quality veterinary care possible. The doctors and staff at each hospital strive to build a long term relationship with their client families and their pets, always making recommendations in the pets best health interest. The Arrow Group of Animal Hospitals offer complete veterinary care from wellness, to vaccines, spays and neuters, dental, surgical and now regenerative medicine. Their animal hospital locations can be easily found at http://www.azpetvet.com.

About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine visit http://www.vet-stem.com or call 858-748-2004.

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The Arrow Group of Animal Hospitals in Central Arizona Partners with Vet-Stem, Inc. to Bring Stem Cell Therapy to ...

Adult Stem Cells Programmed Into Embryonic State

Scientists in Spain said on Wednesday they had made mature cells in living mice revert to their youthful, versatile state, in a step toward the goal of tissue regeneration by stem cells.

Right now, the technique is at its earliest stage and is hedged with safety questions, which makes it impossible to envisage in humans.

But, said the researchers, it opens up a new strategy leading to a beguiling end: that one day damaged tissue will be healed by simply reprogramming nearby adult cells into replacements for the lost or diseased area. A transplant would not be needed.

Stem cells have excited huge interest in medical research.

They are immature cells that differentiate into the specialized cells that comprise and maintain the human body.

In 2006, a team led by Shinya Yamanaka in Japan announced a breakthrough.

A clutch of four genes introduced into adult cells in a lab dish rewound these cells back to their baby state.

These so-called induced pluripotent stem cells -- known by their acronym of iPS -- have since become the most closely-followed innovation in the field.

Despite many hurdles, they are seen by some as being even more promising than embryonic stem cells, the "gold standard" for versatility but a source hotly opposed by moral conservatives.

Reporting in the journal Nature, a team led by Manuel Serrano and Maria Abad of the Spanish National Cancer Research Center created genetically-modified mice that carried the four "Yamanaka genes."

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Adult Stem Cells Programmed Into Embryonic State