Stem Cell Clinic

Experience in Stem Cell Therapy – Video

By adminJuly 5, 2013Uncategorized

Experience in Stem Cell Therapy
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Experience in Stem Cell Therapy - Video

Yevheniya Shevchenko – High School Stem Cell Research Intern June 2013 – Video

By adminJuly 5, 2013Stem Cell Treatment

Yevheniya Shevchenko - High School Stem Cell Research Intern June 2013
The CIRM Creativity Awards support summer internship programs that introduce high school students to stem cell science and foster the next generation of scie...

By: California Institute for Regenerative Medicine

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Yevheniya Shevchenko - High School Stem Cell Research Intern June 2013 - Video

CIDG investigating stem cell doctors

By adminJuly 5, 2013Stem Cell Treatment

Manila, Philippines --- A government official has sought the aid of the Criminal Investigation and Detection Group (CIDG) to investigate doctors who performed stem cell therapy on him which left him "weaker."

A lawyer for Dangerous Drugs Board Chairman Antonio Villar told a media forum yesterday that he is bent on filing charges against the foreign medical team who performed the controversial medical procedure on him at a posh hotel.

"We must first have an investigation on the matter prior to our filing of criminal raps against the three foreign doctors and other individuals who performed the therapy at a five-star hotel in Mandaluyong," said lawyer Claire Pagayanan said.

"The lead doctor was from Germany while the other two doctors and some nurses who assisted them were from Thailand," Pagayanan said.

Senior Supt. Francisco Esguerra, head of the CIDG-Anti-Fraud and Commercial Crime Division, confirmed that Villar is seeking an investigation into the medical team for allegedly performing a bogus stem cell treatment that cost him 15,000 euros.

Esguerra said they expect to identify the foreign suspects and their Filipino cohort in the coming days since Villar has already agreed to cooperate in the investigation.

"We immediately coordinated with the PMA (Philippine Medical Association) and through their help, we were able to convince him (Villar) to file a case," said Esguerra.

During their conversation on Wednesday, Esguerra said Villar disclosed that he met the German physician through a Filipino middleman who told him that stem cell therapy would make him feel young.

"Apparently, he had been hearing about the positive results of stem cell therapy and that is the reason why he agreed," said Esguerra.

"We have to make a thorough investigation because Chairman Villar's case has grave implications, particularly concerning the health of those who are being duped by false claims on the benefits of stem cell procedures," said Senior Inspector Nino Lope Briones said.

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CIDG investigating stem cell doctors

Police probe ‘bogus’ stem cell treatment done on DDB exec

By adminJuly 5, 2013Stem Cell Treatment

A German national and his Thai cohorts are being pursued by Philippine authorities for allegedly conducting a bogus stem cell therapy on a government official for the price of P840,000.

Senior Superintendent Francisco Esguerra of the Criminal Investigation and Detection Group (CIDG) said they are already coordinating with the victim, Dangerous Drugs Board chairman Antonio Villar, for their investigation.

We immediately coordinated with the PMA [Philippine Medical Association] and through their help, we were able to convince him [Villar] to file a case, said Esguerra, who heads the Anti-Fraud and Commercial Crime Division of the CIDG.

Stem cell therapy has been blamed for the deaths of three politicians, according to the Philippine Medical Association (PMA), as it warned the public against unaccredited foreign doctors who are conducting the treatment usually in five-star hotels.

Esguerra said Villar told them that he met the supposed German physician through a Filipino middleman, who had told him that stem cell therapy would make him feel young.

Apparently, he had been hearing about the positive results of stem cell therapy and that is the reason why he agreed, said Esguerra, recalling his conversation with Villar on Wednesday.

He was expecting that he would feel young again, instead he felt sickly after the therapy, he added.

Esguerra also learned from Villar that the procedure was conducted in a posh hotel.

Esguerra said they hope to file a string of criminal charges against the German physician and his group as soon as Villar completes turning over evidence that could be used in the probe. We are also coordinating with the Bureau of Immigration for the identification and other legal actions of those involved, said Esguerra, adding they are expecting the German and his Thai cohorts to have already fled the country.

Investigators are now banking on the Filipino middleman to shed light on the incident.

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Police probe 'bogus' stem cell treatment done on DDB exec

Philippine official sues doctors for fake stem cell treatment

By adminJuly 5, 2013Stem Cell Treatment

Jeannette I. Andrade

Philippine Daily Inquirer

Publication Date : 05-07-2013

At the age of 64, Antonio Villar Jr., chair of the Philippines'Dangerous Drugs Board (DDB), wanted to get rid of the aches and pains that come with aging.

So when he was told about a stem cell procedure, he agreed to the treatment, for which he paid 16,000 euros (US$20,600), in the hope that it would rejuvenate him and make him live longer.

Instead, he felt weaker and feared the procedure even put his life at risk.

Alleging that he was duped into what he now described as a bogus stem cell treatment at a posh hotel in Mandaluyong City in Metro Manila, Villar had asked the police to investigate the group, composed mostly of foreigners, whom he blamed for his failing health.

On Thursday, Villar sent his lawyer, Claire Pagayanan, to a news forum to announce that he was considering filing charges against a German, three Thais and their Filipino agent for the fake stem cell procedure he went through on June 9 last year.

Pagayanan said that after the treatment, Villars prostate gland expanded and he had to undergo radiation therapy.

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Philippine official sues doctors for fake stem cell treatment

DDB chief sues doctors for fake stem cell treatment

By adminJuly 5, 2013Stem Cell Treatment

By Jeannette I. Andrade Philippine Daily Inquirer

Human embryonic stem cells can become any cell in the body. AFP FILE PHOTO

At the age of 64, Antonio Villar Jr., chair of the Dangerous Drugs Board (DDB), wanted to get rid of the aches and pains that come with aging.

So when he was told about a stem cell procedure, he agreed to the treatment, for which he paid 16,000 euros (P854,000), in the hope that it would rejuvenate him and make him live longer.

Instead, he felt weaker and feared the procedure even put his life at risk.

Alleging that he was duped into what he now described as a bogus stem cell treatment at a posh hotel in Mandaluyong City, Villar had asked the police to investigate the group, composed mostly of foreigners, whom he blamed for his failing health.

Pagayanan said that after the treatment, Villars prostate gland expanded and he had to undergo radiation therapy.

With what has been happening caused by the stem cell treatment, he now comes forward to save those who may be victims of fraudulent stem cell therapy, said the lawyer.

Pagayanan said that Villar had submitted a sworn statement and medical abstracts of his condition before and after the treatment to the Criminal Investigation and Detection Group (CIDG).

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DDB chief sues doctors for fake stem cell treatment

Stem cell clinic offers new hope to "Milko"

By adminJuly 5, 2013Stem Cell Treatment

Topics: stem cell therapy, tyson litfin

TYSON "Milko" Litfin is glad to be back home and hopeful stem-cell treatment in Germany will help repair his broken back.

As the QT reported last month, Tyson had a freak motocross crash on May 6 last year that left him paralysed from the waist down.

Desperate to walk again, the 21-year-old, from Grandchester, went to Germany to try stem-cell treatment, returning this week.

"I'm half jet lagged, I think, from the big flight but as soon as I came home I went to the gym and went to physio yesterday.

"They said I won't see any major change until the three-week mark," Tyson said yesterday.

However, he said the doctor who treated him seemed positive about his recovery.

"He said they'd never had anyone get nothing, so you'd definitely get something back. They just can't tell you what it would be," Tyson said.

"They reckon you need to give it six months and do intensive physio, gym, electronic stimulation, floating in a pool.

"He said the people who got the best results come straight back and go straight back into physio and being healthy."

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Stem cell clinic offers new hope to "Milko"

Stem cell gene therapy for sickle cell disease advances toward clinical trials

By adminJuly 5, 2013Stell Cell Research

July 1, 2013 Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells (HSC) from the bone marrow of patients with sickle cell disease (SCD) to treat the disease. The study was led by Dr. Donald Kohn, professor of pediatrics and microbiology, immunology and molecular genetics in the life sciences.

Kohn introduced an anti-sickling gene into the HSC to capitalize on the self-renewing potential of stem cells and create a continual source of healthy red blood cells that do not sickle. The breakthrough gene therapy technique for sickle cell disease is scheduled to begin clinical trials by early 2014. The study was published online in the Journal of Clinical Investigation.

Gene Therapy

Kohn's gene therapy approach using HSC from patient's own blood is a revolutionary alternative to current SCD treatments as it creates a self-renewing normal blood cell by inserting a gene that has anti-sickling properties into HSC. This approach also does not rely on the identification of a matched donor, thus avoiding the risk of rejection of donor cells. The anti-sickling HSC will be transplanted back into the patient's bone marrow and multiplies the corrected cells that make red blood cells without sickling.

"The results demonstrate that our technique of lentiviral transduction is capable of efficient transfer and consistent expression of an effective anti-sickling beta-globin gene in human SCD bone marrow progenitor cells, which improved the physiologic parameters of the resulting red blood cells." Kohn said.

Kohn and colleagues found that in the laboratory the HSC produced new non-sickled blood cells at a rate sufficient for significant clinical improvement for patients. The new blood cells survive longer than sickled cells, which could also improve treatment outcomes. The success of this technique will allow Kohn to begin clinical trials in patients with SCD by early next year.

Sickle Cell Disease

Affecting more than 90,000 patients in the US, SCD mostly affects people of Sub-Saharan African descent. It is caused by an inherited mutation in the beta-globin gene that makes red blood cells change from their normal shape, which is round and pliable (like a plastic bag filled with corn oil), into a rigid sickle-shaped cell (like a corn flake). Normal red blood cells are able to pass easily through the tiniest blood vessels, called capillaries, carrying oxygen to organs such as the lungs, liver and kidneys. But due to their rigid structure, sickled blood cells get stuck in the capillaries and deprive the organs of oxygen, which causes organ dysfunction and failure.

Current treatments include transplanting patients with donor HSC, which is a potential cure for SCD, but due to the serious risks of rejection, only a small number of patients have undergone this procedure and it is usually restricted to children with severe symptoms.

CIRM Disease Team Program

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Stem cell gene therapy for sickle cell disease advances toward clinical trials

Stem-cell cocktail produces human liver tissue in mice

By adminJuly 5, 2013Stell Cell Research

Published: Wednesday, July 3, 2013, 6:42p.m. Updated: Wednesday, July 3, 2013

An international stem cell research team reported on Wednesday that they have grown functioning human liver tissues in mice.

The human liver buds implanted in the mice represent a first experimental step in growing replacement organs from stem cells for transplants, such as liver, pancreas and kidneys, says the research team headed by Japan's Takanori Takebe of the Yokohama City University Graduate School of Medicine. The team relied on a cocktail of so-called induced stem cells grown to resemble the nascent liver bud cells used in the experiment.

The liver bud is formed at the very early stage of development normally in humans, maybe around five or six weeks, Takebe said. We basically mimicked this very early transition process of the liver-bud-forming process.

Discovered in 2006, induced stem cells are grown from mature tissues, typically skin cells, into the unspecialized stem cell state that allows for their cultivation into a wide variety of cell types, from brain to blood to liver cells.

Implanted into mice, the liver buds released human liver enzymes much more effectively than more copious amounts of liver precursor cells implanted alone in mice. The buds also developed blood vessels and grew to resemble normal liver tissues within about two days of implantation. As a final test, the researchers induced a kind of chemically induced liver failure that resembles the disease in people in 12 of the mice, and they report that implanted liver buds helped the mice survive.

Despite the effort's success, Takebe warned that implants of such tissues in human patients are at least a decade away, after tests of their long-term growth and safety.

Stem-cell therapy wipes out HIV in 2 patients

By adminJuly 5, 2013Stell Cell Research

LONDON - Two men with HIV have been off AIDS drugs for several months after receiving stem-cell transplants for cancer that appear to have cleared the virus from their bodies, researchers reported on Wednesday.

Both patients, who were treated in Boston and had been on long-term drug therapy to control their HIV, received stem-cell transplants after developing lymphoma, a type of blood cancer.

Since the transplants, doctors have been unable to find any evidence of HIV infection, Timothy Henrich of Harvard Medical School and Brigham and Women's Hospital in Boston told an International AIDS Society conference in Kuala Lumpur.

While it is too early to say for sure that the virus has disappeared from their bodies altogether, one patient has now been off antiretroviral drug treatment for 15 weeks and the other for seven weeks.

Last July Henrich first reported that the two men had undetectable levels of HIV in their blood after their stem-cell treatment, but at that time they were still taking medicines to suppress HIV.

Using stem-cell therapy is not seen as a viable option for widespread use, since it is extremely expensive, but the latest cases could open new avenues for fighting the disease, which infects about 34 million people worldwide.

The latest cases resemble that of Timothy Ray Brown, known as "the Berlin patient", who became the first person to be cured of HIV after receiving a bone marrow transplant for leukaemia in 2007. There are, however, important differences.

While Brown's doctor used stem cells from a donor with a rare genetic mutation, known as CCR5 delta 32, which renders people virtually resistant to HIV, the two Boston patients received cells without this mutation.

"Dr. Henrich is charting new territory in HIV eradication research," Kevin Robert Frost, chief executive officer of the Foundation for AIDS Research, which funded the study, said in a statement.

Scientific advances since HIV was first discovered more than 30 years ago mean the virus is no longer a death sentence and the latest antiretroviral AIDS drugs can control the virus for decades.

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Stem-cell therapy wipes out HIV in 2 patients