Stem Cell Clinic

Father begins stem cell donation in life-saving cancer treatment for daughter

Mackenzie Furniss, nine, is suffering from an advanced form of childhood cancer but has a last chance of life thanks to a 300,000 treatment devised by a German doctor.

Her father, Jason, 39, has given his stem cells to be used in a bid to eradicate the life-threatening cancer.

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Mr Furniss and his wife, Kimberley, 29, from Sauchie, Clackmannanshire, raised 178,000 towards the treatment before the Scottish Government stepped in with the rest.

The German professor who devised the treatment, Peter Lang, arranged for the treatment to be carried out at the Royal Hospital for Sick Children at Yorkhill, Glasgow.

It is the first time the procedure - haploidentical stem cell transplantation - has been carried out north of the Border and only the second time in the UK.

Mackenzie's treatment started on Thursday and is expected to take six months, including six trips to Professor Lang's clinic near Stuttgart where she will have antibody treatment to reduce the risk of her father's stem cells being rejected.

Mrs Furniss said: "We are just looking forward to the treatment being finished. Mackenzie just wants it to be over now. It's not a simple procedure, and we know it will take a while.

"Mackenzie really just wants to get back to normal and see her friends and go and play."

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Father begins stem cell donation in life-saving cancer treatment for daughter

Chicago Stem Cell Treatment Center: The Future of Regenerative Medicine

Vernon Hills, IL (PRWEB) November 01, 2013

Chicago Stem Cell Treatment Center, a research affiliate of Cell Surgical Network (CSN) provide stem cell therapy for a variety of degenerative conditions by deploying non-embryonic adult mesenchymal stem cells from a patients own adipose tissue or fat (also called Stromal Vascular Fraction (SVF)). The Stromal Vascular Fraction is a broth that contains stem cells and growth factors. We harvest and deploy Stromal Vascular Fraction (SVF) at our Vernon Hills, Illinois location.

Your adipose derived adult stem cells are your body's natural healing cells. They are recruited by chemical signals emitted by damaged tissues to repair and regenerate your damaged cells. Under investigational protocols, adipose derived adult stem cells can be deployed to improve patients quality of life with a number of degenerative conditions and diseases.

We use adipose derived mesenchymal stem cells for deployment & clinical research. Early stem cell therapy research has traditionally been associated with the controversial use of embryonic stem cells. The new focus is on non-embryonic adult mesenchymal stem cells which are found in a person's own blood, bone marrow and fat. Recent technological advances enable us to use adipose derived stem cells with our closed system to keep sterility intact throughout the whole process.

Chicago Stem Cell Treatment Center uses autologous stem cells from a person's own fat that are easy to harvest safely under local anesthesia and are abundant in quantities.

Our current areas of study include; Orthopaedics, Neurology, Autoimmune and Ophthalmology conditions. If you think you may be a candidate for one of our stem cell protocols you may contact Gina Virgilio at (847) 367-8815. For more information please visit our website: http://www.chicagostemcellsinstitute.com.

About Chicago Stem Cell Treatment Center:

At the Chicago Stem Cell Treatment Center, we provide care for people suffering from diseases that may be alleviated by access to adult stem cell based regenerative treatment. The Center utilizes a fat transfer surgical technology to isolate and implant the patients own stem cells from a small quantity of fat harvested by liposuction on the same day. Patients who seek care at the Chicago Stem Cell Treatment Center are evaluated by a respective member of our multispecialty expert panel of Board Certified physicians representing many medical fields. The Chicago Stem Cell Treatment Center emphasizes quality and is highly committed to clinical research and the advancement of regenerative medicine.

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Chicago Stem Cell Treatment Center: The Future of Regenerative Medicine

Stem Cells Therapy

MARLBOROUGH, Mass.(BUSINESS WIRE)

Advanced Cell Technology, Inc. (ACT; OTCBB:ACTC), a leader in the field of regenerative medicine, announced today that its chief scientific officer, Robert Lanza, M.D., will be delivering a Keynote lecture at the World Conference on Regenerative Medicine being held in Leipzig, Germany October 23-25th. The Conference is considered one of the worlds largest and most influential events in stem cells and regenerative medicine, and provides a platform that brings scientists with an academic, clinical and industrial background together. Dr. Lanzas Lecture, entitled ES and iPS Cells Moving into the Clinic, will take place at 9:00 a.m. at the Congress Center Leipzig.

The World Conference will, as in past years, encompass a broad range of topics in regenerative medicine from biomaterials to biomarkers as well as regulation and stem cell technologies. The organizers expect more than 1,000 attendees and hundreds of papers with ground-breaking scientific insights and new results. Furthermore, the conference will host a large exhibition where international researchers and biotechnology companies can demonstrate the reach of current technologys translation and the implementation of research in products. In addition to Dr. Lanzas Keynote Lecture, the Conference will include presentations on cell and immunotherapy, stem cells, cell and tissue engineering, biomaterials and tissue interaction, models of regeneration, molecular mechanisms of regeneration, diagnostic and imaging of regeneration, and regulatory affairs.

About Advanced Cell Technology, Inc.

Advanced Cell Technology, Inc. is a biotechnology company applying cellular technology in the field of regenerative medicine. For more information, visit http://www.advancedcell.com.

Forward-Looking Statements

Statements in this news release regarding future financial and operating results, the relevance and applicability of clinical trials in animals to studying the effect of products in humans, future growth in animal and human research and development programs, potential new applications of and expanded indications covering our technology, the effects of donorless sources of stem cells on potency and the risk of communicable diseases in the manufacturing context, the existence and size of potential or existing market opportunities for the company, the effect of the companys products on the medical needs and quality of life of pets, and any other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not statements of historical fact (including statements containing the words will, believes, plans, anticipates, expects, estimates, and similar expressions) should also be considered to be forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements, including: limited operating history, need for and limited sources of future capital, failures or delays in obtaining regulatory approval of products, risks inherent in the development and commercialization of potential products, reliance on new and unproven technology in the development of products, protection of our intellectual property, and economic conditions generally. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in the companys periodic reports, including the Quarterly Report on Form 10-Q for the three months ended June 30, 2013. Forward-looking statements are based on the beliefs, opinions, and expectations of the companys management at the time they are made, and the company does not assume any obligation to update its forward-looking statements if those beliefs, opinions, expectations, or other circumstances should change. Forward-looking statements are based on the beliefs, opinions, and expectations of the companys management at the time they are made, and the company does not assume any obligation to update its forward-looking statements if those beliefs, opinions, expectations, or other circumstances should change. There can be no assurance that the Companys clinical trials will be successful.

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Stem Cells Therapy

Stem Cell Therapy & Stem Cell Treatment – Cell Therapy Center Emcell

Our Cell Therapy Center offers advanced patented methods of stem cell treatment for different diseases and conditions. The fetal stem cells we use are nonspecialized cells able to differentiate (turn) into any other cell types forming different tissues and organs. Fetal stem cells have huge potential for differentiation and proliferation and are not rejected by the recipients body more...

Stem cell therapy has proven to be effective for organs and tissues restoration, and for fight against the incurable and obstinate diseases. We treat patients with various diseases, such as diabetes mellitus, multiple sclerosis, Parkinsons disease, Duchenne muscular dystrophy, cancer, blood diseases and many others, including rare genetic and hereditary diseases. Among our patients there are also people willing to undergo anti-aging treatment. Stem cell treatment allows for achieving effects that are far beyond the capacity of any other modern method more...

For over 19 years, we have performed more than 7,500 transplantations of fetal stem cells to people from many countries, such as the USA, China, Italy, Germany, Denmark, UAE, Egypt, Russian Federation, Greece and Cyprus, etc. Our stem cell treatments helped to prolong life and improve life quality to thousands of patients including those suffering from the incurable diseases who lost any hope for recovery.

With Cell Therapy Center EmCell located in Kiev, Ukraine, we have numerous partners in various countries devoted to provide medical advice on EmCell stem cell treatment locally.

We are always open for medical, businessandscientificcooperation.

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Stem Cell Therapy & Stem Cell Treatment - Cell Therapy Center Emcell

Phoenix Stem Cell Clinic at Arizona Pain Now Offering Nonoperative Repair of Rotator Cuff Tears

Phoenix, Arizona (PRWEB) October 30, 2013

The Arizona Pain Stem Cell Institute is now offering patients the option to avoid surgery for rotator cuff disorders with stem cell injection therapy. There are multiple different types of treatment including bone marrow, fat, or amniotic derived stem cell injections along with PRP therapy. For more information and scheduling, call (602) 507-6550.

Millions of individuals suffer from rotator cuff disorders including tendonitis, bursitis and tears. For an unfortunate few, conventional treatments are unable to provide sufficient pain relief. With the advent of regenerative medicine treatments exists the potential for pain relief and increased function without the need for a procedure.

At Arizona Pain Stem Cell Institute, Board Certified and Award Winning pain management doctors in Phoenix offer the outpatient treatments which are low risk. The bone marrow and fat are harvested from the patient so there is minimal risk of infection or rejection, while the amniotic derived injections come from consenting donors and processed at an FDA regulated lab. The amniotic injections have been used over 10,000 times world wide without an adverse event.

Platelet rich plasma therapy is also provided at the Institute, with published studies showing satisfactory results for pain relief and increased function. This procedure involves a simple blood draw, with the blood being spun down immediately to concentrate platelets and growth factors for the best chance of healing.

Arizona Pain offers multiple locations, with the pain management doctors offering both medication management and interventional procedures. At the Stem Cell Institute, multiple research studies are ongoing which helps subsidize the cost of treatment.

For more information and scheduling, call (602) 507-6550.

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Phoenix Stem Cell Clinic at Arizona Pain Now Offering Nonoperative Repair of Rotator Cuff Tears

NEJM study evaluates early stem cell transplants for non-Hodgkin's lymphoma

PUBLIC RELEASE DATE:

30-Oct-2013

Contact: Jim Ritter jritter@lumc.edu 708-216-2445 Loyola University Health System

MAYWOOD, Ill. Performing early stem cell transplants in patients with aggressive non-Hodgkin's lymphoma does not improve overall survival in high-risk patients, according to a study published in the New England Journal of Medicine.

But early transplantation does appear to be beneficial among a small group of patients who are at the very highest risk, the study found.

Lead author is Patrick Stiff, MD, director of Loyola University Medical Center's Cardinal Bernardin Cancer Center. The study was developed by the SWOG cancer research cooperative group and funded by the National Cancer Institute. Stiff is chair of the SWOG Bone Marrow and Stem Cell Transplantation Committee.

The traditional first-line therapy for aggressive non-Hodgkin's lymphoma is a combination of four chemotherapy drugs. In recent years, physicians have added a fifth drug, the monoclonal antibody rituximab. This five-drug regimen is known as R-CHOP. The treatment typically puts patients into remission. But many patients relapse and go on to get an autologous stem cell transplant after second-line chemotherapy.

The study was designed to determine whether doing an early stem cell transplant without first waiting to see whether a patient relapses -- would increase survival.

The clinical trial included 40 sites in the United States and Canada. In addition to SWOG, the study included the Eastern Cooperative Oncology Group, Cancer and Leukemia Group B and Canadian NCIC Clinical Trials Group.

The study included 397 patients who were in defined groups of high risk or intermediate-high risk of relapsing. After initial chemotherapy, those who responded were randomly assigned to receive an autologous stem cell transplant (125 patients) or to a control group of 128 patients who received three additional cycles of the R-CHOP regimen. Enrollment began in 1999 and ended in 2007. (Some of the patients in the beginning of the study did not receive rituximab.)

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NEJM study evaluates early stem cell transplants for non-Hodgkin's lymphoma

Stem Cell Therapeutics Receives U.S. Orphan Drug Designation for the Use of Tigecycline to Treat Acute Myeloid Leukemia

TORONTO, ONTARIO--(Marketwired - Oct 31, 2013) - Stem Cell Therapeutics Corp. (TSX VENTURE:SSS)(SCTPF), an immuno-oncology company developing cancer stem cell-related therapeutics, today announced that it has been granted Orphan Drug designation by the U.S. Food and Drug Administration (FDA) for the use of tigecycline in the treatment of acute myeloid leukemia (AML).

Orphan Drug designation is granted to therapeutics treating rare diseases affecting less than 200,000 people in the U.S. The designation entitles the sponsor to seven years of market exclusivity as well as opportunities for additional funding and expert protocol assistance.

"Orphan Drug status significantly enhances the commercial potential of tigecycline in AML, a disease which is notoriously difficult to treat," said the company's Vice President, Drug Development, Dr. Penka Petrova. "Through its unique mechanism of action and synergy with existing AML therapies, tigecycline has the potential to positively impact the standard of care in this disease."

The company's program is based on Dr. Aaron Schimmer's published findings that tigecycline, an FDA-approved antibiotic, selectively targets leukemia cells and leukemic stem cells by inhibiting mitochondrial protein synthesis and thus shutting down the cells' energy supply. A Phase I Canadian and U.S. multicenter dose-escalation clinical trial in patients with relapsed or refractory AML is nearing completion.

"The Orphan Drug designation covers tigecycline as an active ingredient and is independent of the drug formulation," added Dr. Bob Uger, the company's Chief Scientific Officer. "We are investigating improved formulations of tigecycline, which we believe will be critical for the commercialization of this technology."

About Cancer Stem Cells:

The cancer stem cell (CSC) concept postulates that the growth of tumors is driven by a rare population of dedicated cells that have stem cell-like properties, including self- renewal. While the bulk of a tumor consists of rapidly proliferating cells and differentiated cells, neither of which is capable of self-renewal, a small population of CSCs provides for long-term maintenance of the cancer. Although the CSC concept was first postulated in the 1960s, it wasn't until 1994 that proof of their existence was demonstrated, when Dr. John Dick and colleagues in Toronto isolated CSCs (known as leukemic stem cells, or LSCs) from bulk acute myeloid leukemia cells. More recently, CSCs have been identified in many other human malignancies, including solid tumors such as bladder, brain, breast, colon, ovarian and prostate cancers. There is accumulating evidence that CSCs are resistant to conventional chemotherapies and radiation. Thus, CSCs are thought to be responsible for a phenomenon well known to oncologists: most patients will experience an initial response to conventional chemotherapies but will ultimately relapse. To cure cancer CSCs need to be destroyed, but the current armament of therapies is poorly equipped to do so.

About Stem Cell Therapeutics:

Stem Cell Therapeutics Corp. (SCT) is an immuno-oncology company advancing cancer stem cell discoveries into novel and innovative cancer therapies. Building on over half a century of leading and groundbreaking Canadian stem cell research, the company is supported by established links to a group of prominent Toronto academic research institutes and cancer treatment centers, representing one of the world's most acclaimed cancer research hubs. The Company has two premier preclinical programs, SIRPaFc and a CD200 monoclonal antibody (mAb), which target two key immunoregulatory pathways that tumor cells exploit to evade the host immune system. SIRPaFc is an antibody-like fusion protein that blocks the activity of CD47, a molecule that is upregulated on cancer stem cells in AML and several other tumors. The CD200 mAb is a fully human monoclonal antibody that blocks the activity of CD200, an immunosuppressive molecule that is overexpressed by many hematopoietic and solid tumors. SCT's clinical stage programs include the recently in-licensed program focused on the structure of tigecycline, which is currently being evaluated in a multi-centre Phase I study in patients with acute myeloid leukemia (AML), as well as TTI-1612, a non- cancer stem cell asset that recently completed a 28-patient Phase I trial in interstitial cystitis ("IC") patients. For more information, visit: http://www.stemcellthera.com.

Caution Regarding Forward-Looking Information:

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Stem Cell Therapeutics Receives U.S. Orphan Drug Designation for the Use of Tigecycline to Treat Acute Myeloid Leukemia

StemCells, Inc. Acquires Seminal Neural Stem Cell Patent Portfolio

NEWARK, Calif., Oct. 29, 2013 (GLOBE NEWSWIRE) -- StemCells, Inc. (STEM) today announced the acquisition of a portfolio of issued US and Canadian patents to which it had previously held an exclusive worldwide license. The portfolio broadly claims the manufacture and proliferation of purified populations of human neural stem cells and their use as therapeutics and as tools for drug discovery. The acquisition relieves the Company of all milestone and royalty obligations under the license agreements for products claimed by the patents, such as products derived from the Company's proprietary HuCNS-SC(R) cells (purified human neural stem cells). The patents arose from the groundbreaking research of Samuel Weiss, Ph.D., and Brent Reynolds, Ph.D., while at the University of Calgary. As consideration for the portfolio, the Company will issue 139,548 shares of common stock to Neurospheres Holdings Ltd., an intellectual property holding company affiliated with the University of Calgary.

"These Weiss and Reynolds patents have been recognized time and time again as the seminal intellectual property pertaining to purified populations of human neural stem cells," said Martin McGlynn, President and Chief Executive Officer of StemCells, Inc. "The potential value of these patents continues to grow in light of the encouraging data emerging from the clinical trials of our HuCNS-SC cells, and acquiring them outright on these terms was in the best interests of our stockholders.

"Moreover, we have sued a competitor, Neuralstem, Inc., for patent infringement under six of these patents. In the litigation, four of the six patents were submitted by Neuralstem for reexamination by the U.S. Patent and Trademark Office. All four survived reexamination and we look forward to having the opportunity to prove our case of infringement against Neuralstem in court."

Key claims of the acquired patents include, among other things, cultures of neural stem cells derived from any source, including embryonic, fetal, juvenile, or adult tissue; compositions of matter, again regardless of the source of the cells and regardless of whether the cells were grown in either suspension or adherent culture or derived from induced pluripotent stem (iPS) cell technologies. One of the acquired patents, U.S. Pat. No. 7,166,277, has a term extending to 2024 and claims the use of human neural stem cells to remyelinate endogenous host cells, such as to treat spinal cord injury.

About StemCells, Inc.

StemCells, Inc. is engaged in the research, development, and commercialization of cell-based therapeutics and tools for use in stem cell-based research and drug discovery. The Company's proprietary HuCNS-SC(R) cells (purified human neural stem cells) are currently in development as a potential treatment for a broad range of central nervous system disorders. In a Phase I clinical trial in Pelizaeus-Merzbacher disease (PMD), a fatal myelination disorder in children, the Company has shown preliminary evidence of progressive and durable donor-derived myelination in all four patients transplanted with HuCNS-SC cells. The Company is conducting a Phase I/II clinical trial in chronic spinal cord injury in Switzerland, Canada and the United States, and has reported positive interim data for the first three patients. The Company is also conducting a Phase I/II clinical trial in dry age-related macular degeneration (AMD) in the United States. In addition, the Company is pursuing preclinical studies in Alzheimer's disease, with support from the California Institute for Regenerative Medicine (CIRM). StemCells also markets stem cell research products, including media and reagents, under the SC Proven(R) brand. Further information about StemCells is available at http://www.stemcellsinc.com.

Apart from statements of historical fact, the text of this press release constitutes forward-looking statements within the meaning of the Securities Act of 1933, as amended, and the Securities Exchange Act of 1934, as amended, and is subject to the safe harbors created therein. These statements include, but are not limited to, statements regarding the prospect of enforcing the Company's intellectual property against infringers, the potential breadth and length of patent protection in the United States or in any other geography; the company's litigation prospects and potential recovery against Neuralstem; and the likelihood that any of the Company's intellectual property will be found to be valid and enforceable. These forward-looking statements speak only as of the date of this news release. The Company does not undertake to update any of these forward-looking statements to reflect events or circumstances that occur after the date hereof. Such statements reflect management's current views and are based on certain assumptions that may or may not ultimately prove valid. The Company's actual results may vary materially from those contemplated in such forward-looking statements due to risks and uncertainties to which the Company is subject, including uncertainties with respect to the fact that additional trials will be required to confirm the safety and demonstrate the efficacy of the Company's HuCNS-SC cells for the treatment of any disease or disorder; risks whether the FDA or other applicable regulatory agencies will permit the Company to continue clinical testing or conduct future clinical trials; uncertainties regarding the Company's ability to obtain the increased capital resources needed to continue its current and planned research and development operations and to continue its ongoing litigation against Neuralstem; uncertainties regarding the validity and enforceability of the Company's patents; litigation uncertainties; uncertainties as to whether the Company will become profitable; and other factors that are described under the heading "Risk Factors" disclosed in Part I, Item 1A in the Company's Annual Report on Form 10-K for the year ended December 31, 2012 and in its subsequent reports on Form 10-Q and Form 8-K.

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StemCells, Inc. Acquires Seminal Neural Stem Cell Patent Portfolio