House seeks probe on stem-cell therapy link to solons’ deaths

Should there be a law on stem cell therapy? The House of Representatives (HOR) has no idea. And for the sake of finding answer, House leaders intend to consult with medical experts about the issues surrounding the procedure. Speaker Feliciano Sonny Belmonte Jr. admits lawmakers need an expert opinion before they take any legislative action on reports about the negative effects of the expensive treatment. At this point, we have absolutely no basis to say that it was wrong (or) it wasnt wrong (or) it should be regulated, it should not be regulated, Belmonte said. Belmonte issued the statement after the Philippine Medical Association (PMA) said it is looking into the recent deaths of three politicians, who died after receiving xenogenic treatment in Germany. PMA president Dr. Leo Olarte said his group is still trying to find out whether politicians died due to their illness or due to hypersensitive reaction from animal-based stem cell treatments they received. On Monday, Belmonte revealed that Camiguin Rep. Pedro Romualdo underwent stem cell treatment in Germany before he died in April due to pneumonia. Incoming Bohol Rep. Aris Aumentado also admitted his father, the late Bohol Rep. Erico Aumentado, had undergone similar treatment in September before he died last Christmas, also due to pneumonia. We are still awaiting the word of the experts and the medical experts, not political experts on how, if anything, is demanded from us, Belmonte said. Olarte, who is the spokesperson of Philippine Society for Stem Cell Medicine, cited initial information that the politicians received stem cell therapy that used sheeps. He reiterated that receiving animal-based stem cell is dangerous because it may trigger complications such as graft versus host reaction. The expert advised Filipinos and public officials to choose autologous adult stem cell treatment, which is derived from the patients own blood, bone marrow or fat. Last March, the Department of Health (DOH) has restricted hospitals and other facilities from using genetically-altered cells and tissues of human in carrying out stem-cell therapy and treatments in the country. Health secretary Enrique Ona added their department also prohibits the use of umbilical cord, fat-derived human stem cells, and live animal stem cells for the conduct of the procedure locally.

ONA released Administrative Order (AO) 2013-0012, which seeks to ensure the safety of people who want to undergo human stem cell and cell-based therapies.

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House seeks probe on stem-cell therapy link to solons' deaths

Doctors probe deaths of 3 Filipinos after stem cell treatment

Leila B. Salaverria and Jocelyn R. Uy

Philippine Daily Inquirer

Publication Date : 25-06-2013

The late Representative Erico Aumentado of the Philippines' Bohol province underwent stem cell therapy in Germany last September and felt like Superman before he died of pneumonia last Christmas at the age of 72, his son told the Inquirer on Monday.

Aris Aumentado, the incoming representative from Bohol, said his father felt better on his return from Germany that he got rid of his cane and wheelchair.

He was like Superman, he told reporters, a day after the Philippine Medical Association (PMA) issued a warning against the so-called xenogenic, or animal-based, stem cell therapy.

House Speaker Feliciano Belmonte Jr. also said on Monday that Camiguin Rep. Pedro Romualdo also underwent stem cell therapy before he died on April 24 at the age of 77, also of pneumonia.

Aris said his father was advised to rest after the German trip, but because he felt so good, he went around campaigning in his district.

He said that before the procedure, his father had already suffered from thrombosis in his leg because his sugar could not be controlled.

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Doctors probe deaths of 3 Filipinos after stem cell treatment

Cancer Treatment Center Of America Opening Stem Cell Center In NE Phila.

file photo (Credit: SAM PANTHAKY/AFP/Getty Images)

By Lynne Adkins

PHILADELPHIA (CBS) - A local facility is opening a new unit to help patients with certain types of cancer.

The stem cell transplant center at Cancer Treatment Centers of America in Northeast Philadelphia will help patients with such cancers as leukemia, lymphoma, and multiple myeloma. Dr. Pamela Crilley, chief of medical oncology, says the 17,000 square foot facility has eight rooms for patients undergoing stem cell transplants and more.

It has a dedicated infusion center for outpatient treatments and it also has a apheresis section where we will collect stem cells. It has cryopreservation laboratory, Dr. Crilley said this unit will allow the center to treat patients locally, instead of sending them to facilities in other parts of the country.

We have five facilities and so they may have been treated in a different facility than our location here, so this is really expanding what can be done at this location.

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Cancer Treatment Center Of America Opening Stem Cell Center In NE Phila.

After P900K stem cell therapy, PH official feels worse

MANILA - A government official on Thursday said he is no believer in stem cell therapy after undergoing the procedure but getting zero health benefits.

Speaking to radio dzMM, Dangerous Drugs Board chairman Antonio "Bebot" Villar said he was enticed to try out the procedure after hearing from other people about the near-miraculous effect of stem cell therapy.

He noted that even former President Joseph Estrada has attributed his rejuvenated health to stem cells.

"Kasi nababalitaan ko maganda itong stem cell. Ako ay madalas na [masakit] ang buto ko. Siguro nanghihina yung buto ko na at tsaka medyo mahina ang katawan ko kaya sinubukan ko ito," he said.

Villar said he paid 16,000 euros or more than P900,000 to Villamedica for stem cell therapy to cure aches and pains in his bones and general body weakness.

He said he underwent treatment with his wife at Makati Shangri-la hotel, along with at least a dozen others.

"July 9 may schedule na stem cell sa Shangri-la EDSA. Mga dose or kinse kami. Halos buong floor, yun chairman doctor kasama assistants na taga-Thailand," he said.

The DDB chief said he received several injections on the buttocks and ordered to stay in the hotel for a day so doctors could monitor their blood pressure. He said the stem cells were harvested from lambs.

He said that after the treatment, he tried to see if he got stronger but only felt worse.

"Ang lakas ng loob ko at naniniwala ako. Naglakad ako. Abay, sumakit ang mga paa ko. Parang wala itong epekto," he said.

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After P900K stem cell therapy, PH official feels worse

Shockwave Treatment increases the body’s own stem cell production and substantially reduces treatment costs

VIENNA, June 26, 2013 /PRNewswire/ --

On the occasion of the Congress of the International Society for Medical Shockwave Treatment (ISMST) in Salzburg experts present recent international research findings. They demonstrate that medical shockwave treatment stimulates the organism to produce more of its own stem cells to be used in the self-healing process. "In turn, this leads to the successful healing of wounds which otherwise would not heal or would require sophisticated surgery to heal", explains Rainer Mittermayr, Head of Wound Healing Department at the Ludwig Boltzmann Institute for experimental and clinical traumatology.

Shockwave treatment has shown impressive results in the healing of bones and wounds. It helps treating severe trauma cases, using non-invasive procedures. Slow and badly healing wounds such as the diabetic foot ulcer, which is responsible for about two thirds of all amputations, can be brought under control within a short period of time. Moreover, shockwave therapy is used in the treatment of osteoarthritis, cellulite and other medical conditions on a successful basis.

However, there is more: shockwaves also stimulate the mobilization of the stem cells to move to the specific location where they are needed and where they are transformed into the cell type required assisting with the healing process. "Comprehensive scientific studies have finally proven what we had already been able to observe in the treatment of thousands of patients with shockwaves here in Austria," says Mittermayr. Shockwaves initiate the formation of new blood vessels to grow into the tissue, and induce the formation of new tissue and, thus, the healing process - new blood flow to the heart muscle, the growth of new bone tissue and the growth of new skin over wounds. "It would be safe to assume that shockwaves will replace conventional stem-cell research within the next five to 10 years," is Mittermayr convinced.

Shockwaves are as effective as surgery. Just cheaper and less painful.

Recently published studies document that shockwaves are as successful as surgical methods in the treatment of non-healing bone fractures. However, this kind of therapy is superior to surgery in terms of rehabilitation: "Patients who received shockwave treatment showed significantly fewer and less severe complications," says Markus Gleitz, orthopedic surgeon and General Secretary of ISMST. Wolfgang Schaden, Head of the Shockwave department at the AUVA Trauma Centre Meidling adds: "The patients in question recover faster and are rehabilitated more quickly. This is much less painful for the patients and they get back on their feet more quickly and, thus, back to work much faster."

More information: http://auva.celumimagine.com/pindownload/login.do?pin=CHU3Y

Contact: Mag. Gabriela Sonnleitner Ketchum Publico Tel: +43-1-717-86-136 Email: gabriela.sonnleitner@ketchum-publico.at

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Shockwave Treatment increases the body's own stem cell production and substantially reduces treatment costs

DOH: Solons who died after stem cell therapy were sick

MANILA - Two congressmen who died after undergoing stem cell therapy abroad were already sick before getting treatment, Health Secretary Enrique Ona said Tuesday.

Speaking to reporters, Ona refused to say if stem cell treatment caused the deaths of congressmen Erico Aumentado and Pedro Romualdo. Both lawmakers died of pneumonia.

"First hindi ko alam yun. Second, ang information that we got: It has nothing to do Ibig sabihin, they were already very sick bago nagpa-so-called stem call, baka sakali," he said in the interview.

On the other hand, the health secretary said clinics or hospitals in the Philippines offering stem cell treatments should be duly licensed by the Department of Health.

Dapat yung mga clinic or mga ospital na gumagawa noon kailangang mayroong license, approved ngayon ng DOH. Kaya iinspekyunin sila," he said.

House Speaker Sonny Belmonte earlier confirmed Aumentado and Romualdo had died after undergoing stem cell treatment in Germany last year. He clarified that it has not been established whether stem cell therapy was the cause of death.

Belmonte said that after having stem cell therapy, the 2 felt rejuvenated and may have exerted themselves during the last election campaign.

Belmonte said Aumentado even started walking around without a cane.

Aumentado's son, Aristotle, earlier said his father had leg thrombosis for which he had to undergo bifemoral bypass and stem cell therapy .

After stem cell therapy, his father started walking without a cane, and sometimes had low-blood sugar. However, he said they forgot to get him stem cell treatment for his father's pneumonia, which he had before the stem cell treatment in Germany last September.

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DOH: Solons who died after stem cell therapy were sick

Giving hope: The promise of stem cell therapy

MANILA - As stem cell treatment begins to gain traction among Filipinos, a surgeon believes the country is now entering a new phase in medicine.

Dr. Levi John Lansangan, one of the founding members of the Philippine Stem Cell Society, said there is much promise in stem cell therapy because of the hope it gives to ailing patients.

"Before it was only physiologic, then it became pathologic, which deals with diseases. Then it became pharmacologic, wherein we give medicine. But now it is regenerative, wherein the body heals by itself," Lansangan told ANC's "Prime Time" on Wednesday.

Stem cell treatment involves harvesting stem cells, processing them, and injecting them back to the body.

Lansangan said the autologous treatment, which harvests stem cells from the patients own system, is the safest type of stem cell procedure.

The procedure may last for up to 4 hours, depending on the patients health. It may cost up to P1.6 million.

Stem cell treatment is believed to have the potential to cure illnesses including diabetes, heart ailments, brain damage such as Parkinsons and Alzheimers, osteoarthritis, stroke, baldness and even sports injuries.

The hardest thing to say to a patient is hopelessness. If you say there is no hope for the disease, it is very unacceptable for the patient. But with stem cell, were giving hope. Not hope in the sense that we are just giving placebo but hope that there is really something into it thats really big, Lansangan said.

But Lansangan warned that there are also risks involved in the process, particularly if stem cells are derived from animals such as rabbits and black sheep.

There are a lot of sources for stem cell. But the only stem cell sources approved by the DOH [Department of Health] come from the bone marrow, fats and blood of the patient itself. We dont recognize xenograph, or from animals. That is where the problem lies, he said.

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Giving hope: The promise of stem cell therapy

International Stem Cell Corporation to Present Data From Its Parkinson’s Disease Program at Society for Neuroscience …

CARLSBAD, CA--(Marketwired - Jun 27, 2013) - International Stem Cell Corporation (OTCQB: ISCO) (www.internationalstemcell.com) a California-based biotechnology company developing novel stem cell based therapies, announced today that it will present preliminary data from its IND-enabling study in Parkinson's disease at the Society for Neuroscience annual meeting in San Diego, CA on November 10th 2013.

The Society for Neuroscience is the world's largest organization of scientists and clinicians devoted to understanding the brain and nervous system. More than 30,000 people are expected to attend the annual meeting, making it one of the largest scientific and medical conferences in the world.

ISCO's Parkinson's disease program uses human parthenogenetic neural stem cells (hPNSC) which are a novel therapeutic cellular product derived from the company's proprietary histocompatible human pluripotent stem cells. hPNSC are self-renewing mulitpotent cells that are precursors for the major cells of the central nervous system. The ability of hPNSC to (i) differentiate into dopaminergic (DA) neurons and (ii) express neurotrophic factors such as glial derived neurotrophic factor (GDNF) and brain derived neurotrophic factor (BDNF) to protect the nigrostriatal system, offers a new opportunity for the treatment of Parkinson's disease, especially in cases where current small molecule approaches fail to adequately control the symptoms.

About International Stem Cell CorporationInternational Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells (hpSCs) and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs) hence avoiding ethical issues associated with the use or destruction of viable human embryos.ISCO scientists have created the first parthenogenetic, homozygous stem cell line that can be a source of therapeutic cells for hundreds of millions of individuals of differing genders, ages and racial background with minimal immune rejection after transplantation. hpSCs offer the potential to create the first true stem cell bank, UniStemCell. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology (www.lifelinecelltech.com), and stem cell-based skin care products through its subsidiary Lifeline Skin Care (www.lifelineskincare.com). More information is available at http://www.internationalstemcell.com.

Forward-looking StatementsStatements pertaining to anticipated developments, the potential benefits of research programs and products, and other opportunities for the company and its subsidiaries, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates,") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, regulatory approvals, need and ability to obtain future capital, application of capital resources among competing uses, and maintenance of intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the company's business, particularly those mentioned in the cautionary statements found in the company's Securities and Exchange Commission filings. The company disclaims any intent or obligation to update forward-looking statements.

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International Stem Cell Corporation to Present Data From Its Parkinson's Disease Program at Society for Neuroscience ...

Stem-cell treatment trials give family hope

By Clare Speak

For the Post

Five-year-old Nelly Vadoviov is the first Slovak child to undergo an experimental stem-cell treatment, using stem cells from the umbilical cord blood taken at her birth.

The pioneering treatment is for cerebral palsy and is being conducted during clinical trials at Duke University Hospital in the United States.

Nelly was picked to take part in the trial by the Cord Blood Center (CBC) Group, which coordinates and enables the participation of patients in clinical trials of the treatment as part of a project called Pomocnruka, or Helping Hand.

CBC has centers in six countries including Slovakia and the Czech Republic and works within many Czech maternity hospitals, offering collection and preservation of umbilical cord blood, which are rich in stem cells.

The cells are stored in private banks for future use by the child or relatives. There are high hopes among experts of stem-cell treatment of providing a cure for Cerebral Palsy, among other disorders.

According to CBC, most clinical trials for stem-cell treatment take place outside of Europe, which is why they began their cooperation with the U.S. hospital. So far, some 200 children worldwide have undergone the experimental treatment, most of them from the United States. There have been only a handful of patients from Europe.

"The main purpose of our project is to ensure that umbilical blood will not only be conserved but actively used in healing procedures," said Dr. Miroslav Kube, representing CBC. "Our vision is to secure the widest possible use of stem cells from umbilical blood in accordance with new emerging trends in global medicine care."

More than 150 children between the ages of 6 months and 6 years are involved in the program, and each will receive two injections over two years, one containing cord blood and the other a placebo solution. Nelly had her first injection in May this year, and neither her parents nor her doctors know whether she received the placebo or stem cells this time.

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Stem-cell treatment trials give family hope