Stem Cell Clinic

$500K Grant Supports Research on Muscle Growth in Pigs, With Broader Health Implications – Maryland Today

A $500,000 award from the U.S. Department of Agriculture National Institute of Food and Agriculture is supporting University of Maryland-led research to enhance pork production through improved muscle growth in pigs.

While early life nutrition is especially important for how muscles grow and develop, less is known about how these benefits can be passed from mother to offspring during pregnancy. For the $20 billion U.S. pork industry, increased and faster muscle growth would result in healthier animals, less feed and waste to raise that animal, and ultimately a more competitive and sustainable pork industry.

In partnership with the Uniformed Services University of the Health Sciences (USUHS), this work could also have future applications beyond the pork industry to optimize human performance and treat wounded service members.The key to these applications could lie in the epigenetic changes (or changes to how genes are expressed) and stem cell activity caused by a simple supplementbutyric acid.

Over the last decade, weve published some nutritional work in this area showing the impact of butyric acid and other dietary components on the activity of tissue-specific stem cells, and feeding butyric acid to pigs resulted in faster muscle growth, said Chad Stahl, professor and chair in the Department of Animal and Avian Sciences who is leading the research. If we are able to make the muscle fibers grow bigger because of the activity of these muscle stem cells, we want to see what happens if we are giving these compounds to the pregnant sow during fetal development.

Stahl conducted previous research in this area with his former student, Robert Murray Ph.D. 18. Now an assistant professor with USUHS and a lieutenant in the U.S. Navy, he is a co-investigator on this grant.

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$500K Grant Supports Research on Muscle Growth in Pigs, With Broader Health Implications - Maryland Today

EU approves bluebird bio’s CALD gene therapy Skysona – PMLiVE

The European Commission (EC) has approved bluebird bios gene therapy Skysona for the rare inherited neurological disease cerebral adrenoleukodystrophy (CALD).

The EC has cleared Skysona (elivaldogene autotemcel) for the treatment of early CALD in patients under the age of 18 years old with an ABCD1 gene mutation who do not have a matched sibling blood stem cell donor.

The approval is supported by data from the phase 2/3 Starbeam study as well as the ongoing phase 3 ALD-104 study.

In the phase 2/3 Starbeam study evaluating Skysona, 90% of CALD patients met the month 24 major functional disability- (MFD) free survival endpoint as of the last data cutoff date.

MFDs are the six severe disabilities commonly attributed to CALD, which have the most severe effect on a patients ability to function independently.

In addition, 26 out of 28 evaluable patients maintained a neurologic function score (NFS) less than or equal to one until month 24, with 24 of those patients having no change in their NFS.

All the patients who completed the Starbeam study enrolled for long-term follow-up in the LTF-304 study. The majority of patients that enrolled in LTF-304 96.3% - remained alive and maintained their MFD-free status through their last follow-up on study.

The median duration of follow-up was 3.2 years and 14 patients reached at least their year five follow-up visit.

bluebird bio was founded with the mission of developing a therapy to recode CALD on the genetic level, and todays announcement represents over twenty years of research and development that has laid the groundwork for future gene therapies to be possible, said Andrew Obenshain, president of severe genetic diseases at bluebird bio.

CALD is a progressive and fatal neurodegenerative disease that overwhelmingly affects males. It involves the breakdown of myelin the protective sheath of nerve cells in the brain that is responsible for muscle control and thinking.

The condition is caused by mutations in the ABCD1 gene that affect the production of ALDP which eventually causes damage to the adrenal cortex and white matter of the brain and spinal cord.

Skysona is designed to add functional copies of the ABCD1 gene into a patients hematopoietic stem cells (HSC).

Once this functional gene is added to a CALD patients stem cells, the patient's body can produce the adrenoleukodystrophy protein (ALDP), which is believed to allow for the breakdown of very-long-chain fatty acids that build up to toxic levels in the brain.

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EU approves bluebird bio's CALD gene therapy Skysona - PMLiVE

Biomedical Warming and Thawing Devices Market Revenue to Cross USD 308 Mn by 2027: Global Market Insights Inc. – Markets Insider

SELBYVILLE, Del., July 20, 2021 /PRNewswire/ -- According to the latest report "Biomedical Warming and Thawing Devices Market by Product (Manual, Automatic), Sample (Blood Products, Ovum/Embryo, Semen), End-use (Hospitals, Research Laboratories, Pharmaceutical Industry, Blood Banks and Transfusion Centers), Regional Outlook, Price Trends, Competitive Market Share & Forecast 2027", by Global Market Insights Inc., the market valuation of biomedical warming and thawing deviceswill cross $308 million by 2027.

Increasing volume of research in the biotechnology sector for development of regenerative medicine, precision surgery, personalized therapeutics and immunotherapy among others is augmenting the demand for thawing devices and is expected to grow significantly. According to a recently published report, in 2019 and 2020, the biotech sector witnessed double-digit growth related to fundraising from venture capitalists and co-developments, joint ventures and partnerships among biotech companies is further increasing the research activities. As per the Lancet journal, the global biomedical research expenditure is projected to reach around a quarter of a trillion U.S. dollars annually in the coming years. Increased funding and financial support for biotech research activities will further promote the use of cryopreserved samples.

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Biotechnology research incorporates cryopreserved cells, tissues and other products on a high scale. For instance, cryopreserved primary neuronal cells and cardiomyocytes are frequently utilized in neuroscience and cardiology research. Cryopreserved biologics are extensively deployed in biotech research in multiple fields such as stem cell research, discovery science, diagnostics development and genomics. These products are essential for supporting several cell-based applications, including stem cell therapy, assisted reproduction and tissue engineering. Ongoing developments in these areas have increased the clinical demand of cryopreserved products.With the growing utilization of cryopreserved cells, the demand for biomedical warming and thawing devices is anticipated to surge at an accelerated rate in the coming years. Moreover, the rising developments in bioengineered products intended to facilitate therapeutics in several diseases are further poised to fuel the biomedical warming and thawing devices market growth.

The automatic segment in the biomedical warming and thawing devices market was valued at over USD 59 million in 2020. The use of automated warming and thawing devices reduces several drawbacks of water-bath-based and conventional manual approaches. These devices incorporate mechanical heating mechanism, and computerized control and monitoring, thereby eliminating user-to-user variability and offers consistent process that exterminates the need of intervention from user. Automated thawing devices have an extensive range of applications and can be applied successfully to be used in non-cellular therapeutic materials including plasma samples. In addition, considering the quality assurance aspect in biomedical warming and thawing, automated systems offer standardized, rapid warming rate and temperature read-out of the thawing process in certain cases for monitoring traceability are driving the rising preference for automated systems.

The biomedical warming and thawing devices market for ovum/embryo segment will showcase 9.3% growth rate through 2027 led by the growing infertility rates and increasing adoption of in vitro fertilization (IVF) and embryo transfer. According to the Centers for Disease Control and Prevention (CDC), around 6% of married women in the U.S. belonging to the 15 to 44 years age group face infertility concerns and around 12% of women face difficulty carrying a pregnancy to term. The growing prevalence of infertility has led to acceptance of treatment measures such as in vitro fertilization (IVF) or embryo transfer that incorporates cryopreserved or thawed embryos. According to the National Embryo Donation Academy of U.S., there are approximately 1,000,000 embryos in storage in the country as of 2021 and the number has almost doubled with the number of embryos around 500,000 in 2011. Furthermore, the high success rate of embryo cryopreservation, the rising use of vitrification that provides enhanced outcomes and identical IVF pregnancy rates are further slated to promote the product demand. Patients are increasingly receiving embryo cryopreservation for a broad range of indications, and their number has increased significantly.

The pharmaceutical end-use segment in the biomedical warming and thawing devices market is anticipated to reach USD 35 million by 2027 on account of the increasing research spending and studies in the pharmaceutical sector. Stem cells, blood components and other tissues host a great potential for wide range of applications in pharmaceutical and medical research. Advancements in diagnostic technologies have facilitated growing utilization of cell-based functional assays in drug development and discovery process in the pharmaceutical industry. Screening assays that incorporate cryopreserved cells reduces day-to-day variation, eliminates passage effects that is hampering the research and improvises the precision and consistency of cell-based assay outcomes. Additionally, the launch of advanced products in the biomedical warming and thawing devices market that offers clinical benefits in research is further set to promote the product adoption rate.

Brazil's biomedical warming and thawing devices market is estimated to grow at 8.4% CAGR by 2027 owing to the rising incidence of accidental injuries across the country. According to the World Health Organization (WHO), the burden of road accidents and associated mortality is more than 1.2 million people on yearly basis and nearly over 90% of these accidents occur in low- and middle-income economies such as Brazil. Brazil's road accident mortality rate per 100,000 people is over 20 and is significantly higher than surrounding countries. As per the World Health Rankings, around 43,698 deaths were reported associated with road traffic accidental mortalities in Brazil, accounting for 3.96% of total deaths in 2018. The increasing incidence of accidents and accidental injuries would require blood transfusion for managing the patient's health, thereby fostering the demand for cryopreserved blood and blood components.

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Some of the major players operating in thebiomedical warming and thawing devices market are Helmer Scientific, Brook Life Sciences, Sartorius AG, Sarstedt AG & Co. KG, Boekel Scientific, Barkey, Cytiva, Cardinal Health, and BioLife Solutions. These companies are implementing several strategies such as product launches, research collaborations, distribution partnerships to strengthen their industrial positioning.

Table of Contents (ToC) of the report:

Chapter 3Biomedical Warming and Thawing Devices Market Insights

3.1 Industry segmentation

3.2 Industry landscape, 2016 - 2027 (USD Million)

3.3 Industry impact factors

3.3.1 Growth drivers

3.3.2 Industry pitfalls & challenges

3.4 Growth potential analysis

3.4.1 By product

3.4.2 By sample

3.4.3 By end-use

3.5 COVID-19 impact analysis

3.6 Porter's analysis

3.7 Competitive landscape, 2020

3.8 PESTEL analysis

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https://www.gminsights.com/toc/detail/biomedical-warming-and-thawing-devices-market

About Global Market Insights Inc.

Global Market Insights Inc., headquartered in Delaware, U.S., is a global market research and consulting service provider, offering syndicated and custom research reports along with growth consulting services. Our business intelligence and industry research reports offer clients with penetrative insights and actionable market data specially designed and presented to aid strategic decision making. These exhaustive reports are designed via a proprietary research methodology and are available for key industries such as chemicals, advanced materials, technology, renewable energy, and biotechnology.

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biomedical-warming-and-thawing.png Biomedical Warming and Thawing Devices Market Growth Predicted at 8.5% Through 2027: GMI Major biomedical warming and thawing devices market players include Helmer Scientific, Brook Life Sciences, Sartorius AG, Sarstedt AG & Co. KG, Boekel Scientific, Barkey, Cytiva, Cardinal Health, and BioLife Solutions.

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Biomedical Warming and Thawing Devices Market Revenue to Cross USD 308 Mn by 2027: Global Market Insights Inc. - Markets Insider

Secrets and pies: the battle to get lab-grown meat on the menu – The Guardian

Not a week goes by without Elliot Swartz receiving at least one request from researchers asking him where they can find cell lines (a cell culture developed from a single cell) for use in cellular agriculture an essential tool for creating lab-grown meat. One of the most important things that cell lines offer is that they enable researchers to just get started in this new field, says Swartz, who works in New York as a senior scientist at the Good Food Institute (GFI) a nonprofit focused on advancing cellular agriculture and bringing its products to our shelves and stomachs as quickly as possible. Helping researchers is a core part of his role. In the case of cell lines, however, theres very little he can do.

Swartzs response to the researchers is unfortunately always the same: at the moment, publicly available cell lines relevant for cellular agriculture dont really exist. That doesnt mean that theyre nowhere to be found. Upside Foods (previously Memphis Meats) has submitted several patents to protect cell lines it has developed, and companies such as Cell Farm Food Tech have built a business around selling cell lines for profit. Keeping discoveries behind closed doors is a pattern of behaviour found in private companies across the industry, which many believe is slowing down innovation.

Cellular agriculture is the use of animal cells or microbes to grow animal products, such as meat or milk, in bioreactors. The field gained prominence after Dutch scientist Mark Post unveiled the first cultured meat burger in 2013. Since then, cultured meats have been touted as a sustainable alternative to livestock farming, which is the leading cause of habitat destruction. Global demand for burgers and bacon is to increase over the coming decades, meaning more ecosystems will be bulldozed to accommodate the expanding market. This, in turn, will increase the risk of future pandemics, as biodiversity loss is linked to the emergence of new diseases. Moreover, efforts to cut carbon emissions will also fall short of Paris targets if we dont reduce our meat consumption, according to a special report published by the Intergovernmental Panel on Climate Change in 2019.

There is some progress. In Singapore last year, Eat Just became the first cultured meat company to gain regulatory approval to sell its product. But many technological, social, and economic hurdles remain before our supermarkets are filled with a variety of cultured cutlets. To surpass these hurdles, organisations including the GFI are pushing for a more public exchange of data, tools and ideas. As it stands, most research in the field is done by private companies which seem keen to protect their intellectual property.

Swartz says the lack of publicly available cell lines is a gatekeeper in getting people into the field, even though theres a lot of interest, adding that this isnt really an issue in other industries. Scientists looking for stem cells for research or clinical purposes can go to the government-funded UK Stem Cell Bank, and across the Atlantic, the nonprofit American Type Culture Collection hosts a reserve of cell lines that are mainly open access. Although repositories like this do include animal cells, that doesnt mean theyre suitable for generating meat.

What makes cell lines themselves so useful is that they are immortal and can multiply indefinitely, so they can be used as a standard model across the industry. Were not going to understand if our findings are true if different groups are using different cells with different features, Swartz continues. So cell lines are the first piece of the puzzle for getting cultivated meat to become an actual field of study. The GFI is filling the cell-line-shaped hole in cellular agriculture by funding the creation of lines that will be openly accessible, and making a repository to store them in. Kerafast a Boston-based bioresearch company will maintain this repository. Researchers not involved with the GFI are welcome to deposit cell lines too, as are private companies; anyone looking to use the cells must pay a small fee to cover the costs of storing and maintaining them. So far, only one academic group has deposited a cell line. The lines being worked on in academic groups are still in development, which is why we havent got that many yet, Swartz says.

The reluctance of private companies to share their cell lines may in part be because of how they are financed a GFI report found that of the $366m invested in cultured meat in 2020, only around $12m came from public sources. Controlling the vast majority of the capital in the industry means that the private sector can comfortably dictate the pace and direction of innovation, which the Breakthrough Institutes food and agriculture analyst Saloni Shah sees as an issue. With the government and public sector funding research you can set criteria and standards, and make sure the right kinds of technologies get funded so that the development of the sector accelerates and improves, says Shah.

The complaint that governments need to start investing in more sustainable food options is echoed by Isha Datar, the executive director of New Harvest another nonprofit focused on advancing cellular agriculture. She thinks one of the reasons the field lacks government funding is that it is a mix of tissue engineering, which is medically oriented, and food science. Cellular agriculture is kind of homeless and so it falls in between the cracks of the existing pillars of funding and how we think about science being separated, she says. Swartz also agrees that more public funding is needed, but he thinks it will only come after the technology has been scaled up. Does this industry scale? is going to be the key to opening the floodgate for governments funding this technology, he says. Open source research is going to be really important for bringing new ideas on how to scale this technology or lower costs.

Swartz also complains that secrecy is holding up the industry-wide adoption of other cheaper, more efficient materials. For example, all of the nutrients needed for animal cells to grow into chunks of meat are contained in the cell culture medium, but the industry standard foetal bovine serum is expensive, and must be extracted from the foetus of a slaughtered cow. Many startups claim to have developed alternatives, but they remain trade secrets. Companies tend not to patent these things, because by patenting a cell culture medium you have to include everything thats in there, which is open sourcing what the ingredients are, says Swartz.

Even if the cell line problem were solved, there would still be technological hurdles holding the field back from large-scale commercialisation. Using computer modelling to address these hurdles and accelerate the intensification of cultured meat production is a central goal of the Cultivated Meat Modeling Consortium (CMMC).

Modelling is a useful tool that allows researchers to simulate experiments before entering a laboratory. This helps to save on time and resources. In order to run more complicated simulations, however, modellers first need data from simpler experiments that detail the fundamental biological processes behind cultured meat production to understand the sum of the whole, we must first analyse the parts. Were experiencing quite some difficulty in getting the information we need to actually build models, says Jaro Camphuijsen, a researcher associated with the CMMC. Private companies they work with have shown resistance to sharing data and running certain experiments. We have been talking to a cultivated meat company quite a lot, and we often ask: What happens if you do this experiment? The answer is usually: We dont know, and We arent going to do that because the cells will die, Camphuijsen explains. But failed experiments, he says, can provide useful data points that often reveal more than successful tests. Experiments that go wrong actually provide lots and lots of information if you want to find out how these tiny systems of cells are behaving.

When asked to respond to accusations that industry secrets were slowing down innovation in the field, Uma Valeti, the CEO of Upside Foods, wrote in an email that the firm kickstarted the cultured meat movement when we were founded in 2015. Without that, the industry wouldnt be in the place it is today, where there are hundreds of companies, NGOs, academic groups and government institutions focusing on cultured meat, across every continent but Antartica. He adds that Upside is actively supportive of more open access research on cultured meat, and it has actively supported the development of public research institutions like the Cultured Meat Consortium.

What's the point of lab-grown meat when we can simply eat more vegetables? | Jenny Kleeman

Responding to the same accusations, Robert E Jones, head of public affairs at Mosa Meat, wrote: Few companies have done more than Mosa Meat to contribute to the open advancement of cellular agriculture. He adds that Mosa hoped the 2013 burger would trigger a moonshot level of public investment in research, and that there is something to be said for an innovation ecosystem that includes both private capital and public investments for a challenge as big as reforming the food system.

The idea that governments need to start investing in more sustainable food options is echoed by Datar. She has concerns about a field that lacks an academic basis and publicly accessible information. It means cellular agriculture is going to have to be more transparent than other industries, says Datar. I think we need a lot more data sharing and a lot more transparency if we are to create a better food system. Will private companies heed this call for more transparency and build on their claims that they are supportive of more open access research, or will they follow the approach in other sectors where financial gain has been prioritised over societal benefits? Campaigners hope the answer is one that puts the planet before profit margins.

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Secrets and pies: the battle to get lab-grown meat on the menu - The Guardian

A Recovery for All Of Us: New York City Invests $1 Billion in Life Sciences – Brooklyn Daily Eagle

Editors note: Job development in retail and high-tech is blooming along Brooklyns waterfront. From Brooklyn Navy Yard to Industry City and Brooklyn Army Terminal (BAT) literally billions of dollars are being invested in job growth. This EXPLAINER from the Citys EDC in June helps set the stage for a new announcement in the news about the latest development at BAT.

Mayor de Blasio and the NYC Economic Development Corporation (NYCEDC) announced on June 9 a plan to double the Citys $500 million investment in life sciences to $1 billion as part of LifeSci NYC, a commitment launched in the Mayors State of the City address to create jobs and establish New York City as the global leader in life sciences. This expanded initiative is expected to generate 40,000 jobs.

Mayor de Blasio kicked off this next chapter of the citys support for this industry by announcing aRequest for Proposals(RFP) to help advance the commercial research and development of new medicines, medical devices, diagnostics, materials, and research tools. The City will provide up to $112 million in City capital to award $20 million to support one or more innovation projects. Multiple awardees can access up to $20 million each.

New York City can do more than just fight back COVID-19. We can invest in fast-growing sectors like the life sciences to stop the next pandemic before it starts and become the public health capital of the world, said Mayor Bill de Blasio.This expansion will accelerate the growth of local researchers and businesses inventing the cures for whatever comes next. Its the key to our economic and public health recovery, and it will produce more effective and more equitable health outcomes for New Yorkers across the five boroughs.

A recovery for all requires making the City healthier giving every neighborhood and every household access to the best preventive health care and treatment available. To do that, we are committing today to make New York City the public health capital of the world. Todays investment will foster life sciences research, innovation and manufacturing, making the City the place where diagnostics, therapeutics and improvements in health care delivery are invented, tested and made available to the world, all while providing good-paying jobs to our incredibly talented, well-educated, and driven workforce, said Deputy Mayor for Housing and Economic Development Vicki Been. By doubling our original investment, we ensure both that health care will be fairer for all New Yorkers, and that New York City will bethe incubator for public health innovation full stop.

Strengthening our commitment to LifeSci NYC bolsters our pipeline of job opportunities in life sciences innovation and supports the creation of construction jobs as we build new infrastructure, saidSenior Advisor for Recovery Lorraine Grillo. This expanded investment in life sciences affirms New York Citys leadership in advancing public health, developing treatments, finding cures, and ensuring a recovery for all of us.

Building a healthier city means ensuring the life science sector is equipped with the greatest potential for cutting-edge technologies and treatments for all New Yorkers, saidRachel Loeb, president and CEO of the New York City Economic Development Corporation. With a diverse talent pool, a network of premier academic and medical institutions, New York City is positioned to grow as a global leader in life sciences research and innovation. Were thrilled to expand LifeSci NYC by investing in more talent, companies, and innovative spaces to help us recover and build a stronger economy for all.

Over the next decade, New York City will expand its investment to $1 billion to develop the life sciences industry by launching new commitments as part of LifeSci NYC. The program will invest an additional:

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I applaud Mayor de Blasio and NYCEDC for investing in the future of New York City with an additional investment of $500M to the citys life science initiative, LifeSci NYC, saidRep. Carolyn B. Maloney(NY-12). New York City has long been a national leader in life science innovation. This new investment will cement our city as a leader in life science innovation, critical to our preparedness for future pandemics, everyday illnesses, and other maladies affecting human health.

This pandemic has shown the need to invest in research and development of life sciences. The Bronx, the entire City and State of New York were drastically impacted by COVID-19, saidBronx Borough President Ruben Diaz Jr.Doubling the initial investment of $500 million to $1 billion dollars, will ensure New York City will stay at the forefront of cutting-edge discoveries, cures and treatments. In order to stay ahead we need to have secured infrastructure. As the Bronx Borough President, I know the need for up-to-date equipment and the announcement of the RFP for $20 million in capital to one or more recipients will assist them tremendously.

COVID-19 has had devastating consequences for Queens and the entire City, but we can prevent future health emergencies from having a similar impact by investing now in potentially life-saving research and development, saidQueens Borough President Donovan Richards Jr.We are proud that Long Island City in Queens is leading in life sciences innovation, and the investments announced today will help us go even further in the areas of pandemic prevention and preparedness. This funding shows our City is committed to the growing life sciences sector and will not let the lessons of COVID-19 go unheeded.

I applaud the forward thinking investments that the City will make as part of the LifeSci initiative to expand our capacity as a world leader in fighting pandemics and increase life sciences research and development, said Council Member Paul A. Vallone, Chair of the Committee on Economic Development, It is more important now than ever to ensure that we have a diversified economy in our city that spurs new research and creates jobs that will prevent future public health catastrophes.

Recovery means investing in long-term economic opportunities that will grow and physically stay in New York, and we continue to hear how the life science industry views our city as an important partner and geographic foothold into the future. The LifeSci NYC vision for the next decade fosters new businesses and equitably expands technical talent among our residents, which will help keep our city at the forefront of the economy of tomorrow, saidCouncil Member Carlina Rivera.

By taking a multi-factorial approach attentive to real estate, taxes, talented workers, academic collaborations, and cash the NYCEDC has dramatically expanded the life science industries in our city over the past few years, said Harold Varmus, MD, Weill Cornell Medicine. The Mayors decision to extend his successful initiative will sustain the progress already made and encourage further growth as the City recovers from the pandemic and increasingly recognizes the importance of the health-supporting sciences in its future economy.

It has been exciting for the Advisory Council to contribute to the excellent progress that New York City has made since 2016 in its journey to build a world class biotechnology ecosystem, saidVicki Sato, PhD, Professor of Management Practice, Harvard Business School. With Mayor de Blasios commitment to economic growth and the focused work of the EDC, we have visibility to 2M square feet of new laboratory space coming online by 2023, we have seen growth to over $2Bn of venture investment in 2020, we have launched a vibrant internship program that helps young people compete for important jobs, and most important, we have seen the creation of many new companies committed to improving healthcare. We look forward to continuing the work.

The Lasker Foundation joins leaders across New York City and beyond in celebrating the inspiring vision of a thriving life science ecosystem in our community, saidClaire Pomeroy, President, Albert and Mary Lasker Foundation. Building on our outstanding academic research and healthcare institutions, the increasing presence of biomedical companies and innovative start-ups, experienced investment institutions, and diverse engaged stakeholders, New York City is an ideal place for further growth and expansion of life sciences. As companies specializing in biotechnology, diagnostics, therapeutics, digital health and more choose the City as their preferred location, we see New York City as the home to future innovative breakthroughs that will support better health for all.

At Kallyope, we have witnessed first hand the benefits of being headquartered in New York City, saidNancy Thornberry, CEO, Kallyope.As an early-stage biotechnology company focused on pursuing novel therapeutics for diseases of high unmet need in a fundamentally new way, access to the Citys extraordinary talent pool, technologies, and academic centers has proven invaluable in our ability to deliver on our mission. We strongly encourage leaders across the industry to consider building their next life sciences venture in New York City.

New Yorks biotech ecosystem is unique in its diversity in the kinds of discoveries being made, in the kinds of scientists involved, and in the kinds of impacts that these will potentially have on the world, saidKevin Gardner, Director of Structural Biology Initiative, CUNY Advanced Science Research Center (ASRC). LifeSci NYC has played a transformational role in recognizing the strength of this diversity, and in turn ensuring that these great ideas and people get their chances to realize their potentials all while staying here in New York. I cant imagine a better investment for our city, our scientists and students, and our ideas.

LifeSci NYC has established New York as a hub for the life sciences and biotech industry, putting the city on the map for entrepreneurs starting new businesses, while spurring a flood of private sector investment, saidMaria Gotsch, President and CEO of the Partnership Fund for New York City. Last year, the industry hit a record high in jobs and venture capital funding, demonstrating New Yorks value as a central access point to other industries and commercial activity. The citys decision to double down on this initiative sends a strong message that New Yorks life science community is a smart bet and will play an essential role in the regions economic recovery.

About LifeSci NYC With a diverse talent pool, more than 100 disease-specialty foundations, 370 federally qualified health centers, 50 hospitals, and nine world-leading academic medical centers, New York City is home to one of the largest concentrations of life sciences research. Building on these advantages, NYCEDC established Lifesci NYC in 2016 to form industry partnerships, create thousands of good-paying jobs, and drive key life sciences investments in New York City. The program has helped cement New York Citys place on the map in life sciences, with pharmaceutical and biotech companies attracting more than $1 billion in annual venture investment in 2020 up from $130 million in 2016. The city has unlocked two million square feet of new life sciences innovation space, provided 400 students with paid internships at top life sciences companies, and opened six new incubators yielding 150 start-up companies every two to three years.

The Citys network of life sciences companies, institutions, and industry partners helped throughout the COVID-19 pandemic with broad response for testing, treatment, and vaccination programs. This included working directly with NYCEDC on the development of local supplies for PPE and test kits, the launch of the Pandemic Response Laban award for the local development of a rapid test at Columbia University and the ongoing development of a Pandemic Response Institute.

LifeSci NYC has invested $38 million in city capital to fundapplied research and development facilities at four of New York Citys leading scientific research institutions Columbia University, Einstein College of Medicine + Montefiore Medical Center, the New York Stem Cell Foundation, and Rockefeller University. In addition, the program has launched BioLabs @ NYULangone, the citys largest wet-lab incubator, and partnered withDeerfield Management and King Street Propertiesto develop more than 500,000 square feet of new lab space. The City will continue to build out research and development to establishLifeSci Avenue stretching from the Pandemic Response Institute in Kips Bay in the South through East Harlem in the North. This corridor will anchor the Citys public health vision with neighborhood clusters across the City Long Island City, Sunset Park, Central Brooklyn, Hudson Square, Manhattans West Side, West Harlem, Upper Manhattan, and Morris Park to build a complete network of life science innovation. To learn more about LifeSci NYC, visit lifesci.nyc.

About NYCEDC New York City Economic Development Corporation creates shared prosperity across New York Citys five boroughs by strengthening neighborhoods and creating good jobs. NYCEDC works with and for communities to provide them with the resources they need to thrive, and we invest in projects that increase sustainability, support job growth, develop talent, and spark innovation to strengthen the Citys competitive advantage. To learn more about our work and initiatives, please visit us onFacebook,Twitter, orInstagram.

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A Recovery for All Of Us: New York City Invests $1 Billion in Life Sciences - Brooklyn Daily Eagle