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Global Platelet Rich Plasma Market Recent Trends and Developments, Challenges and Opportunities, key drivers and Restraints over the Forecast Period…

Global Platelet Rich Plasma MarketIndustry Trends and Forecast to 2027 New Research Report Added to Databridgemarketresearch.com database. The report width Of pages : 350 Figures: 60 And Tables: 220 in it. The report makes available an overview of the industry which is gaining momentum in the last few years. The market report uses a range of steps for collecting, recording, analysing and interpreting market data to make this report all-inclusive. It also offers an outline of the industry that might promote interest among prospective investors, large corporations and everyday users who could participate in the next big opportunity or make their lives just a little easier. The Global Platelet Rich Plasma Market report comprises of the list of leading competitors, strategic industry analysis and the insights of key factors influencing the industry.

Global Platelet Rich Plasma Market is expected to rise from its initial estimated value of USD 182.10 million in 2018 to an estimated value of USD 519.83 million by 2026, registering a CAGR of 14.01% in the forecast period of 2019-2026. This rise in market value can be attributed to the increasing usage of platelet rich plasma therapy in therapeutic areas.

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Global Platelet Rich Plasma Market by Type (Pure p Platelet-Rich Plasma, leukocyte-rich platelet-rich plasma, pure platelet-rich fibrin, leukocyte-rich platelet-rich fibrin), Origin (Allogeneic prp, Autologous prp, Homologous prp), Application (Orthopedics, Dermatology, Dental, Cardiac muscle injury, Nerve injury, others), End-user (Hospitals & Clinics, Research Institutions), Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) Industry Trends & Forecast to 2026

Competitive Analysis:

Global platelet rich plasma market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of platelet rich plasma market for global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Key Market Competitors: Global Platelet Rich Plasma Market

Few of the major competitors currently working in the Platelet Rich Plasma market are T-Biotechnology (Turkey), Arthrex, Inc (U.S.)., Terumo BCT, Inc. (U.S.) , EmCyte Corporation (U.S.), DePuySynthes (U.S.), Zimmer Biomet Holdings, Inc (U.S.), Stryker (U.S.) , Glofinn OY (Finland), Dr. PRP America (U.S.), AdiStem, Ltd. (Australia), Arteriocyte Medical Systems, Inc. (U.S.), CellMedix Holdings, LLC (U.S.), Exatech, Inc (U.S.) . Cesca Therapeutics, Inc. (US), Nuo Therapeutics, Inc.(US), Regen Lab SA (Switzerland),. Cytomedix Inc. (US), China Biologic Products Inc. (CHINA), CSL Ltd.(Australia) , Biotest AG(Germany) , Among Others.

Market Definition: Global Platelet Rich Plasma Market

Platelet rich plasma is used in surgical procedures to repair augment tissue and enhance repairing of soft tissue. Platelet rich plasma therapy relieves pain by promoting long lasting healing of musculoskeletal conditions and it is used for treatment of arthritis, tendonitis, ligament sprain and tear.

Market Drivers

Market Restraints

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Segmentation: Global Platelet Rich Plasma Market

Key Developments in the Market:

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Global Platelet Rich Plasma Market Recent Trends and Developments, Challenges and Opportunities, key drivers and Restraints over the Forecast Period...

Insiders Advice: Prevent Shoulder Surgery With These 5 Options (12/17/20) – Southeast Missourian

Thursday, December 17, 2020

The shoulder joint is the most mobile and least stable joint in your body. The more mobile a joint is, the less stable it is; and the more stable a joint, is the less mobile it is. If a joint is functioning properly, it will not degenerate or cause pain.

When a joint stops functioning correctly, it breaks down and becomes painful, causing us to not move it as much. This results in it becoming dehydrated and reduces joint space, causing damage, degeneration, and pain.

The most common shoulder issues are degeneration and rotator cuff injuries.

Traditional medical treatments include steroid injections, medications, and surgery, which focus on reducing the pain, symptoms, and have inherent risks and downtime. They also dont focus on restoring the function of the joint to stop the damaging process.

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Here are some of the functional medical treatments available at PC Medical Centers:

1. PRP (Platelet Rich Plasma) injections Plasma is injected into the shoulder joint, improving the healing response and function of the joint as well as increasing the joint space.

2. Regenerative Medicine injections High in Mesenchymal Stem Cells, this injection helps tissues regrow and heal.

3. Lidocaine and Sterile Solution injections Adds fluid to the joint and increases the joint space, improving the ability to move the joint.

4. Physical Therapy PT helps improve joint stability by improving the muscle tone around the joint.

5. Chiropractic Care Helps improve joint mobility by adjusting the joint, which improves the function.

Other options include Laser Therapy, Acupuncture, Myofascial Release (muscle work), and nutrition. Our goal is to get the patient back to doing what they would like, with little to no downtime. We assess the patient, identify the functional limitations, and create a personalized plan to restore the function to the joint.

Call 573-335-9188 by the end of December to schedule your free consultation with PC Medical Centers.

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Insiders Advice: Prevent Shoulder Surgery With These 5 Options (12/17/20) - Southeast Missourian

Walking The Tight Rope With Dinelson Lamet | RotoGraphs Fantasy Baseball – fangraphs.com

Stability is important in fantasy baseball, especially when it involves early-round picks. When we talk stability it can mean two things. It can mean stability of health or stability of skill set. With your early-round picks you of course want players with very few holes in their skills and players who stay on the field. I now present you with someone who teeters on a tight rope with both health and skill set: Dinelson Lamet.

Feeding off his late surge in 2019 Lamet came into 2020 like a tiger eyeing down its prey. He pounced on the competition lighting a fire from within and produced a phenomenal 2.09 ERA, .086 WHIP, and 27 K-BB%. A fantastic season for sure. He was able to have an elite season by changing his pitch mix and throwing his slider over 50% of the time. A true Patrick Corbin blueprint.

Lamets slider could arguably be called the best pitch in baseball. Last season it produced a .197 wOBAcon, 23 SwStr%, and 19.7 pVAL. It induced weak contact, created whiffs, and was utilized to perfection. It was utilized so well that his 19.7 pVAL was the highest of any pitch in baseball. The next closest was Marco Gonzales fastball which had a 14.3 pVAL (love me some Marco). Overall a great pitch. One small flaw to point out about Lamets slider is his command.

All over the place. It looks like he wants to push it low and away but he was only able to achieve that 40% of the time, a percentage that ranks second-worst in the league. Whats crazy is that even when he leaves it in the heart of the plate it still produces great results. Opposing hitters only had a .068 ISO and .103 wOBA against it. Compare that to Kenta Maedas slider which had a .524 ISO and .456 wOBA when left in the same location. That is clearly a testament as to how good his slider is that even when he misses, it doesnt matter. Im curious as to if that can continue.

Next up is his four-seam fastball, a pitch he threw 37% of the time. Meaning his slider and fastball make up for 91% of his pitches, making him a two-pitch pitcher (problem number one). The fastball took some big strides this year compared to last season.

Dinelson Lamets Fastball

This shows you the chain reaction of Lamets four-seam development. The velocity rose over one mile per hour causing an uptick in vertical movement. Because of the increased movement hitters werent able to jump on it like the season before. Although the overall 2020 numbers arent exactly great compared to the league average, they were good enough to elevate his game.

If you stopped right there everything seems great for Lamet besides the obvious caveat of only having two pitches. Here is the problem with Lamets new increased velocity. In the month of August, his fastball averaged 97.2 MPH. In all five of his starts it sat over the 97.0 mark. Come September his fastball average 96.9 MPH. Only two of his five starts did he eclipse 97.0 MPH. The way I interpret this is Lamet knew it was a short season, he knew he could push his velocity and it eventually started to normalize on him.

On the chart you can see the massive decline as the season went on. But you see where it climbs back up towards the end of the season? For two starts in September he pushed it back up to 97 MPH and what do you think happens when you push your arm too hard? In his last start of the year Lamet was pulled with bicep tightness.

The bicep issue turned into an elbow issue, symptoms of biceps and elbow injuries can show up in similar ways. Since there is no ligament damage the Padres decided to go the PRP (platelet-rich plasma therapy) route. This is a big issue because not only has Lamet needed Tommy John surgery in the past but pitchers who have had PRP injections have ended up needing the surgery anyway. Look no further than his former teammate Garrett Richards.

This makes Lamet a major injury risk, but lets say he takes the shots and it works. How will he be able to push his fastball velocity for an entire season? We have to expect regression on his fastball and when that happens you get the 2019 version of Dinelson Lamet. That leaves you with a 4.07 ERA, 1.26 WHIP, and 24 K-BB% from your likely SP2.

Does taking a player in the first four rounds who is walking on a tight rope sound like someone youd like to roster? With a current overall ADP of 65 and as the 24th pitcher off the board Dinelson Lamet becomes a spine-chilling acquisition. Reaching the other side is unlikely and falling one way or the other seems evident.

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Walking The Tight Rope With Dinelson Lamet | RotoGraphs Fantasy Baseball - fangraphs.com

Facts you should know about Osteoarthritis – The New Indian Express

Express News Service

KOCHI: Osteoarthritis, commonly known as OA, is a joint disease caused by the disintegration of cartilage in a joint in the body. It is primarily found in weight-bearing joints such as the ankle and knee but also arises in joints of the hand as a result of daily activity. Knee joint OA is a progressive disorder. The degeneration of the articular cartilage (white tissue that protects bones from rubbing against each other) causes knee pain, stiffness and a weakened joint structure.

While cartilage serves as a natural cushion between the bones, synovial fluid lubricates and supplies adequate oxygen to the joint, facilitating smooth joint motion in a healthy individual. Over time, the cartilage weakens and becomes thinner, resulting in roughness around the joint. As this develops, pain and swelling of the knee come into play, making everyday movements such as walking or sitting laborious. Stage one OA is minor and is usually accompanied by minimal pain or discomfort. The joint looks normal on x-ray.

In stage two, bone deposits called Osteophytes grow in number around the joint as the cartilage weakens further. Stiffness aggravates, especially after the person stays in a sitting position for long periods of time.Moderate OA or stage three is when day-to-day activities such as walking, running, bending and kneeling cause distress owing to loss of cartilage and inflammation. As OA advances into the severe stage four, symptoms are very prominent. Cartilage breaks down, joint fluid reduces, diagnosis shows bone against bone contact and even walking becomes painful.

To boost overall joint health, an anti-inflammatory diet may be followed. This includes antioxidant-rich foods like fruits and vegetables, extra virgin olive oil and low-fat dairy products like cheese, milk and yogurt which are high in vitamin D and calcium. Excess body weight can increase pressure around the knee joint and, in turn, cause inflammation.

Immediate pain relief for OA is possible with standard medications such as Paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), opioids, superficial creams, etc. To reduce unbearable pain, direct steroid injections have also been employed in the past. PRP or Platelet Rich Plasma is a newly-found regenerative therapy that is extremely effective for knee OA. When PRP is injected into the joint, its dose is certified according to need.

The technique has been proven to greatly reduce knee pain and stiffness, gradually bringing back ease of movement to the patient. This process, combined with other medicines and physiotherapy, triggers the natural healing tendencies of the patients blood.Severe cases of OA are treated with surgeries such as total knee replacement (TKR) or high tibial osteotomy (HTO).The author is a consultant orthopaedic surgeon at Regencare, Kochi.

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Facts you should know about Osteoarthritis - The New Indian Express

Garrett Richards is the epitome of a risk-reward free agent – Bless You Boys

Free agent righthander Garrett Richards is one of the most successful what could have been stories of the past decade. Eye-popping stuff sabotaged by a lengthy injury history have made him a staple on lists of buy low candidates in fantasy baseball over the past few seasons. Yet despite it all, hes still put together a nice career thus far in the majors. The Detroit Tigers are in a situation where they can afford to place a small bet here, and Richards may offer more bang for your buck than any free agent out there.

Of course, theres a good reason why hes potentially available to a non-contender like the Tigers at this point in his career. While hed be a fascinating project to gift to new pitching coach Chris Fetter, Richards is something of a wild card at this point due to a mishandled elbow injury. Hes as likely to miss half the season as to give you 25 starts. Of course, you can pick up seemingly durable pitchers and get the same result, as the Al Avila led Tigers have proven repeatedly.

The odyssey of Garrett Richards elbow began in 2016. After three full seasons in the majors for the Los Angeles Angels, he was coming off a 2015 season in which he spun 207 13 quality innings and appeared to be coming into his own as a durable young starting pitcher who might be a tweak or two from stardom. Unfortunately, he suffered a partial tear to his UCL early in 2016 and missed most of the season. The solution would normally be Tommy John surgery, but Richards and the Angels, desperate to get back to the playoffs, elected instead to try platelet rich plasma injections. The hope was to use that treatment in combination with rehabilitation and get him back on the mound in 2017 rather than losing the whole season to surgery. This, like many decisions about pitchers the Angels have made in recent years, turned out terribly.

Richards ultimately made just six starts in 2017. He suffered a nerve issue in his biceps the first week of the season, and while imaging seemed to indicate that his UCL was undamaged, a string of related issues kept him off the field most of the season. Things seemed more promising in 2018. Richards came into the season apparently healthy, upped his breaking ball usage, and was posting the best strikeout rates of his career. It all came undone during a July 10th start against the Seattle Mariners. His UCL finally blew out and there was no other recourse than to finally undergo Tommy John surgery well over two years after the initial injury occurred.

Richards became a free agent after the 2018 season, and the San Diego Padres offered a two-year speculative deal hoping hed be fully healthy in time for them to cash in with him in 2020. Richards got back on the mound for a few innings late in the 2019 season, and miraculously his stuff was intact. He wasnt great for the Padres in 2020, but its par for the course to have some struggles returning from Tommy John surgery. What was encouraging was the fact that he was able to make 10 starts, stay healthy, and look pretty good at times. The Padres decided to put him in the bullpen in September in preparation for a super-reliever role in the postseason, but a 4.03 ERA, 4.28 FIP performance returning from Tommy John surgery is still fairly strong.

One of the wilder parts of this whole saga is that Richards has basically looked unchanged throughout. His fastball velocity has held up consistently despite the injury issues. His calling card, and the reason hes consistently of interest to pitching honks, is the elite spin rates he produces on his fastball, slider, and curveball, and those metrics have also remained elite throughout the injuries as well. His physical ability remains relatively undiminished.

Apart from the injury history, the one relative weakness for Richards has been the underwhelming movement on his fourseam fastball. In 2020, he averaged 95.1 mph, with a spin rate of 2626 rpms. Only 11 starters with 300 fastballs registered in Statcast this season threw harder. Only Trevor Bauer posted a higher average spin ratewhich is a story in itselfthan Richards did. Yet hes never managed anything like the kind of whiff rates produced by the Justin Verlanders and Max Scherzers of the power stuff set. Richards fastball spin is actually quite inefficient, as he checks in with well below average vertical and horizontal movement.

In an era when strikeouts rule, a fastball that doesnt generate many whiffs just isnt going to be highly valued, but in Richards case that can also be a little deceiving. His fastball does produce plenty of weak contact. Even in seasons when the average exit velocity of fastballs put into play spiked for him, he still gives up little power because his heavy, weird fourseamer is hard to lift with authority. Over the last four seasons combined, hitters have posted an ISO of just .155 and six total home runs against it. In some ways, Richards fastball is actually reminiscent of Spencer Turnbulls heater, another fourseamer with above average spin rate, but which somehow moves more like a power sinker.

Richards backs the fastball with a nasty pair of breaking balls. The slider is his main out pitch, checking in at 88.5 mph with a spin rate of 2893 rpms, premium spin rate for that class of pitch. Over the years hes really leaned into the slider and at this point he throws fastballs or sliders over 90 percent of the time. He does have a fairly monstrous curveball in his back pocket as well. He spins the curve in with an average of 3299 rpms, which is best in its class level spin rate as well. Each has well above average depth and Richards gets a lot of whiffs with each of them.

In recent years he hasnt commanded either pitch quite as well, leading to the occasional meatball, but overall his control has never been a problem. He doesnt issue that many free passes, but he hasnt always had consistent command and bite on his stuff either. The hope would be that with Richards now finally beyond his elbow issues, his old home run suppressing ways may return with sharper command.

This is actually a pretty good time for the Tigers to take a risk on an oft-injured but talented pitcher. His case is a bit of an extreme, but betting on pitchers returning to form in their second season following a return from Tommy John is a smart move, assuming said team isnt pinning their whole playoff hopes on it. Richards will still draw offers from contending teams, so it isnt a particularly likely fit, but if Al Avila could manage to add him to the rotation for 2021, suddenly the pitching staff has a chance to be pretty interesting. If things went well, theyd also have a pretty good trade chip.

Of course, the issue we havent addressed is fitting Richards into the rotation. MLB Trade Rumors projects a contract of two years, $16 million. That should easily be within range of the Tigers budget even assuming theyd like to add a veteran to both the outfield, the infield, and to address the catcher position. On a yearly AAV basis, Richards would cost roughly as much as Matt Boyd and Michael Fulmer would make in arbitration combined over the next two seasons. Of course he has more upside than either, and is less risky in terms of injuries than Fulmer.

On paper, the Tigers 2021 rotation is Spencer Turnbull, Matt Boyd, Michael Fulmer, Casey Mize, and Tarik Skubal, but apart from Turnbull there are questions marks with the whole group. And as we laid out a few weeks ago, even if all five current starters are healthy and perform relatively well, theyre still not going to provide the Tigers nearly enough innings to get through the season. Figuring out how to manage workloads is obviously now A.J. Hinch and Chris Fetters job, and theyre well aware the Tigers are going to need more pitching to avoid pushing their young prospects unwisely.

Theres been a lot of discussion among Tigers fans this offseason about what constitutes aggressive moves to get better versus simply spending on the top free agents. Sure, it could go wrong, but a minor two year investment doesnt constitute any real financial risk either. Richards is a pretty good example of a player who isnt particularly risky and has good upside. The Tigers will probably have to beat some other offers to land him, and they should.

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Garrett Richards is the epitome of a risk-reward free agent - Bless You Boys