Global Precision Cancer Therapies Market 2020: Analysis, Industry Growth, Current Trends and Forecast till 2025 – The Daily Philadelphian

The recently updated and published report titled Global Precision Cancer Therapies Market 2020 by Company, Type and Application, Forecast to 2025, by MarketQuest.biz comprises an exhaustive study of the market that gathers important and crucial information of market size, growth rate, market possibilities, and market revenue forecast from 2020-2025. The report can assist the stakeholders to understand key trends and prospects in the global Precision Cancer Therapies market as well as identify the growth opportunities and competitive scenarios. Crucial aspects covered in the report include key market trends, key dominating players, chapter-wise segregation. Mainly, the report promotes an ambitious landscape of the market, business overview, their policies, and recent developments.

NOTE: Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers post COVID-19 crisis. The report aims to provide an additional illustration of the latest scenario, economic slowdown, and COVID-19 impact on the overall industry.

Company Profiles:

Every market participant needs to be familiar with the competitive scenario in the global Precision Cancer Therapies industry. The industry research report layouts historical and forecast market data, demand, application details, price trends, and company shares of the leading player by geography. The industry analysts have examined the strategic activities of the competitors to help the key players increase their competitiveness. The report studies the progress of leading players based on crucial parameters, including market share, new developments, global reach, local competition, price, and production. Some of the major companies included in the report are: Abbott Laboratories, Aveo Pharmaceuticals, OncoGenex Pharmaceuticals, Bayer HealthCare, AstraZeneca, GlaxoSmithKline, Boehringer Ingelheim, Hospira

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The study provides an in-depth overview of country-level break-up classified as potentially high growth rate territory, countries with the highest market share in past and current scenario. Some of the regional break-up classified in the study are: North America (United States, Canada and Mexico), Europe (Germany, France, United Kingdom, Russia and Italy), Asia-Pacific (China, Japan, Korea, India, Southeast Asia and Australia), South America (Brazil, Argentina), Middle East & Africa (Saudi Arabia, UAE, Egypt and South Africa)

Market segmentation by product: Hormone Therapy, Immunotherapies, Targeted Therapy, Monoclonal Antibody Therapy, Gene Therapy

Market segmentation by application: Hospitals, Diagnostic Centers, Oncology Clinics, Research Institutes

In the regional analysis, the report highlights the prospective region, which is estimated to generate opportunities in the global Precision Cancer Therapies market in the forthcoming years. The report incorporates data regarding the supply and demand situation, the competitive scenario, and the challenges for market growth. Components such as market drivers, restraints, challenges, and opportunities for the market are explained in detail. The report additionally provides a complete assessment of the expected behavior about the future market and changing market scenario.

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Key Deliverables of The Report Are As Follows:

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This report can be customized to meet the clients requirements. Please connect with our sales team ([emailprotected]), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on +1-201-465-4211 to share your research requirements.

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MarketQuest.biz is a leading global Market Research agency providing expert research solutions, trusted by the best. We understand the importance of knowing what global consumers watch and buy, further using the same to document our distinguished research reports. MarketQuest.biz has worldwide presence to facilitate real market intelligence using latest methodology, best-in-class research techniques and cost-effective measures for worlds leading research professionals and agencies. We study consumers in more than 100 countries to give you the most complete view of trends and habits worldwide. MarketQuest.biz is a leading provider of Full-Service Research, Global Project Management, Market Research Operations and Online Panel Services.

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Global Precision Cancer Therapies Market 2020: Analysis, Industry Growth, Current Trends and Forecast till 2025 - The Daily Philadelphian

Cutting-edge Treatment Offers Hope to Infant With Spinal Muscular Atrophy – Adventist Review

November 17, 2020

By Sheann Brandon, Loma Linda University Health

Loma Linda University Childrens Hospital in Loma Linda, California, United States, recently gave its first administration of a new gene replacement therapy to an infant who screened positive for spinal muscular atrophy(SMA). SMA is the top genetic killer of children under the age of two, and the treatment potentially provides a symptom-free life for the patient.

Childrens Hospital physicians said the new drug therapy Zolgensma is a revolution in neurological pediatric care.

This therapy represents a new opportunity for us to intervene and change childrens long-term prospects, and sometimes if we can treat the disease in time, we can restore them to full health, David Michelson, chief of the division of child neurologyand director of the pediatric muscular dystrophy association clinics at Childrens Hospital, said. This therapy is a chance to wipe a patients health slate clean.

The patient was diagnosed with SMA through the state of Californias newborn screening program. Even though the patient seemed perfectly healthy during the first weeks of life, the health-care team worked against the clock to treat the patient before the first onset of symptoms. Studies have shown that infants who receive the therapy as soon after diagnosis as possible have better outcomes than those who receive delayed treatment.

SMA is a rare genetic disease that causes a persons muscles to weaken and become smaller over time. In an infant, this affects development, including crawling, walking, sitting, and head control. Severe types of SMA affect the muscles used for swallowing and breathing and, untreated, lead to ventilator dependence and a high risk of mortality.

According to Michelson, the patients neurologist, there are four types of SMA. These types differ in their severity and at what age they will manifest in a persons body. SMA type I, the most common of the severe forms, can present in infants as early as three months and is often fatal by the age of two.

The new therapy involves one of only three approved drugs to treat SMA in children under two and is the only single-dose treatment option for SMA patients. Hospitals across the country are only beginning to provide this therapy to qualifying patients since the treatment received U.S. Food and Drug Administration (FDA) approval in May 2019.

Michelson said he and his team dont yet know exactly how the treatment will affect the patient.

We may not know how much we helped, since we were able to treat him before he developed symptoms, Michelson said. Best case scenario is he will never develop any symptoms of the disease.

The original version of this story was posted on the Loma Linda University Health news site.

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Cutting-edge Treatment Offers Hope to Infant With Spinal Muscular Atrophy - Adventist Review

Molecular Testing With Universal Method Comparable to Traditional Method in Hereditary Solid Tumors – Targeted Oncology

In multiple solid malignancies, including breast, ovarian, colorectal, and pancreatic cancers, there is a subset of patients with a hereditary predisposition for these diseases, but the current testing criteria do not mention this subset. In an effort to provide more information of genetic testing in this population, a study of Memorial Sloan Kettering Cancer Center (MSKCC) patients was conducted to test the traditional guideline-based method of testing versus universal testing of a broad cancer patient population over a 5-year period.

A total of 7235 patients were included in the analysis and tested for 76 to 88 cancers. Through this study, investigators uncovered pathogenic and likely pathogenic (P/LP) variants in 7.5% (95% CI 6.6%- 8.4%) of 3,341 patients with breast cancer, 17.4% (95% CI, 14%- 21.6%) of 384 those with ovarian cancer, 13.5% (95% CI, 9.8%- 18%) of 252 patients with colorectal, and 8.8% (95% CI, 5.1%-14.8%) of 136 patients with pancreatic cancer.

Overall, the study found that testing with universal method was comparable to the guideline-based method, implying that universal testing can expand genetic testing to patient populations who are in need but are currently underserved.

In an interview with Targeted Oncology during the 2020 Association for Molecular Pathology (AMP) Annual Meeting, Ozge Ceyhan-Birsoy, PhD, assistant directorof the Laboratoryfor Molecular Medicine, MSKCC, discussed genetic testing methods for patients with hereditary predisposition and the molecular research underway at MSKCC to improve testing in this patient population.

TARGTED ONCOLOGY: In recent years, what advances have we see in cancer genetics?

Ceyhan-Birsoy: There have been significant advances in the range of genetic testing options for cancer patients in recent years. More patients are now able to receive molecular testing on their tumors to identify optimal targeted therapies for their cancer and germline genetic testing to uncover hereditary cancer predisposition. A paired analysis of tumor and normal DNA is increasingly being adapted, which improves the interpretation of both somatic and germline mutations. Additionally, incorporation of RNA analysis has expanded the scope of mutations that can be detected and characterized. Finally, the use of cell-free DNA now allows us to profile a patients tumor using only their blood.

TARGETED ONCOLOGY: How can hereditary predisposition inform oncologist for care/treatment decisions?

Ceyhan-Birsoy: Identifying hereditary mutations that predispose patients to cancer has important implications for their treatment and management. There are established targeted therapies available now for certain germline defects. For instance, germline mutations in certain homologous recombination and mismatch repair genes can predict response to PARP inhibitor and immune-checkpoint inhibitor therapies, respectively. Some therapies may pose high risk for patients with particular gene mutations, such as radiation therapy risks for patients with germline TP53 mutations. In addition, identifying hereditary cancer predisposition is critical to allow timely surveillance and prophylactic interventions for future cancers that the patient may be at higher risk of developing. As germline mutations are heritable, this information provides the opportunity for early surveillance in the patients family members, as well.

TARGETED ONCOLOGY: Can you explain how this MSKCC study came about?

Ceyhan-Birsoy: Genetic testing for hereditary cancer predisposition is traditionally performed in a guideline-dependent and targeted manner. In current practice, only patients who meet established criteria from national and professional organizations receive genetic testing and typically get tested for a small number of genes selected based on their tumor type, age of onset, and family histories. MSKCC has been 1 of the first institutes to pilot a universal testing approach for cancer patients, providing comprehensive germline testing of all known cancer predisposition genes without pre-selection of patients based on traditional genetic testing criteria. We have been performing both targeted and universal testing for our patients since 2015.

In this study, we aimed to understand how the yields (positive rates) of these 2 testing approaches compare to each other in greater than 4000 patients who had traditional and more than 9,000 patients who had universal testing at MSKCC in the past 5 years. We also assessed whether universal testing identified additional findings that would have been missed in a targeted testing approach for any given patient.

TARGETED ONCOLOGY: What are the key results of this analysis?

Ceyhan-Birsoy: We saw that universal germline testing without preselection of patients based on current guidelines yielded comparable rates of positive results to traditional guideline-dependent testing approach, particularly in patients with breast, ovarian, and pancreatic cancers. In addition, universal testing uncovered mutations that predispose to other cancers in about 9% of patients in genes that are not routinely tested for their diagnosis. Approximately half of those conferred high to moderate risk to cancer and about 40% of them implicated early surveillance or prophylactic surgery recommendations to prevent other cancers.

TARGETED ONCOLOGY: What is a key takeaway from your AMP 2020 presentation and explain the implications of these findings?

Ceyhan-Birsoy: Our results suggest that the preselection of patients for genetic testing based on the current guidelines may not significantly increase the likelihood of identifying a germline mutation in certain patient populations. A universal and comprehensive testing approach further provides the benefit of identifying hereditary risk for other cancers, allowing early surveillance and prophylactic interventions.

TARGETED ONCOLOGY: How can this information be applied in oncology clinics?

Ceyhan-Birsoy: Our study underlies the advantages of universal and comprehensive testing for cancer patients. However, there are many challenges that may limit the application of this approach for all cancer patients, including the cost of testing, resources needed to provide pre-test and post-test genetic counseling to patients, and the potential to discover more variants of uncertain significance that may lead to higher number of inconclusive results. Future efforts should be dedicated to providing wider groups of cancer patients access to genetic testing, which can aid in their clinical care and in the care of their family members.

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Molecular Testing With Universal Method Comparable to Traditional Method in Hereditary Solid Tumors - Targeted Oncology

Alpha Thalassemia Market Research Provides an In-Depth Analysis on the Future Growth Prospects and Industry Trends Adopted By the Competitors |…

Global Alpha Thalassemia Market 2025 Report Provides Porters Five Forces Analysis Illustrates the Potency of Buyers & Suppliers Operating in the Industry & the Quantitative Analysis of The Global Market from 2019 to 2025 is Provided to Determine the Market Potential.

Alpha Thalassemia Market Data and Acquisition Research Study with Trends and Opportunities 2019-2025 The study of Alpha Thalassemia market is a compilation of the market of Alpha Thalassemia broken down into its entirety on the basis of types, application, trends and opportunities, mergers and acquisitions, drivers and restraints, and a global outreach. The detailed study also offers a board interpretation of the Alpha Thalassemia industry from a variety of data points that are collected through reputable and verified sources. Furthermore, the study sheds a lights on a market interpretations on a global scale which is further distributed through distribution channels, generated incomes sources and a marginalized market space where most trade occurs.

Along with a generalized market study, the report also consists of the risks that are often neglected when it comes to the Alpha Thalassemia industry in a comprehensive manner. The study is also divided in an analytical space where the forecast is predicted through a primary and secondary research methodologies along with an in-house model.

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The following manufacturers are covered: Bluebird Bio Novartis Kiadis Pharma Acceleron Pharma

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Segment by Regions North America Europe China Japan

Segment by Type Iron Chelating Drugs Gene Therapy

Segment by Application Hospitals Private clinics Other

For a global outreach, the Alpha Thalassemia study also classifies the market into a global distribution where key market demographics are established based on the majority of the market share. The following markets that are often considered for establishing a global outreach are North America, Europe, Asia, and the Rest of the World. Depending on the study, the following markets are often interchanged, added, or excluded as certain markets only adhere to certain products and needs.

Here is a short glance at what the study actually encompasses: Study includes strategic developments, latest product launches, regional growth markers and mergers & acquisitions Revenue, cost price, capacity & utilizations, import/export rates and market share Forecast predictions are generated from analytical data sources and calculated through a series of in-house processes.

However, based on requirements, this report could be customized for specific regions and countries.

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Major Point of TOC:

Chapter One: Alpha Thalassemia Market Overview

Chapter Two: Global Alpha Thalassemia Market Competition by Manufacturers

Chapter Three: Global Alpha Thalassemia Production Market Share by Regions

Chapter Four: Global Alpha Thalassemia Consumption by Regions

Chapter Five: Global Alpha Thalassemia Production, Revenue, Price Trend by Type

Chapter Six: Global Alpha Thalassemia Market Analysis by Applications

Chapter Seven: Company Profiles and Key Figures in Alpha Thalassemia Business

Chapter Eight: Alpha Thalassemia Manufacturing Cost Analysis

Chapter Nine: Marketing Channel, Distributors and Customers

Chapter Ten: Market Dynamics

Chapter Eleven: Global Alpha Thalassemia Market Forecast

Chapter Twelve: Research Findings and Conclusion

Chapter Thirteen: Methodology and Data Source 13.1 Methodology/Research Approach 13.1.1 Research Programs/Design 13.1.2 Market Size Estimation 13.1.3 Market Breakdown and Data Triangulation 13.2 Data Source 13.2.1 Secondary Sources 13.2.2 Primary Sources 13.3 Author List 13.4 Disclaimer

About HongChun Research: HongChun Research main aim is to assist our clients in order to give a detailed perspective on the current market trends and build long-lasting connections with our clientele. Our studies are designed to provide solid quantitative facts combined with strategic industrial insights that are acquired from proprietary sources and an in-house model.

Contact Details: Jennifer Gray Manager Global Sales + 852 8170 0792 [emailprotected]

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Alpha Thalassemia Market Research Provides an In-Depth Analysis on the Future Growth Prospects and Industry Trends Adopted By the Competitors |...

Intrathecal Pumps Market 2020 Industry Size and Share Evolution to 2026 by Growth Insight, Trends – The Daily Philadelphian

The Global Intrathecal Pumps Market to gain from rapid technological advancements taking place in the market. Recently Fortune Business Insights has published a report, titled Intrathecal Pumps Market Size, Share and Global Trend By Medication (Baclofen, Hydromorphone Morphine, Clonidine, Midazolam, Bupivacaine, Ziconotide), By Application (Pain Management, Spasticity Management), By End Users (Hospitals & Clinics, Ambulatory Surgery Centers, Others), and Geography Forecast till 2026

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Intrathecal Pumps Market 2020 Industry Size and Share Evolution to 2026 by Growth Insight, Trends - The Daily Philadelphian

$30 billion to fight COVID-19 over next five years – Sydney Morning Herald

NSW will commit $29.6 billion to a COVID-19 health and economic package over the next five years following unprecedented emergency health spending to weather the pandemic.

Treasury forecasters are working on an assumption that a vaccine will be available by mid-next year, with an estimated 20 per cent of people vaccinated by October.

NSW will spend a total of $1.6 billion on COVID-19 programs in 2020-2021 including $500 million to support COVID clinics, quarantine programs, extra pathology testing and contact tracing.Credit:Getty/Lisa Maree Williams

Social distancing restrictions are likely to be maintained until a vaccine is widely available and most of the population immunised.

Up to $1.6 billion of the COVID-19 response budget will be used for 2020-2021 health programs, including $500 million to support clinics, quarantine programs, extra pathology testing and contact tracing.

More than $458 million will be used to fast track elective surgeries delayed by the pandemic and $20 million will accelerate COVID-specific research and clinical trials.

Some $385 million will be used to purchase additional personal protective equipment.

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Treasurer Dominic Perrottet described the mental health toll as one of the pandemics most insidious hidden costs.

More than $66 million will fund additional mental health clinicians and peer workers, expanding the Police, Ambulance and Clinical Early Response model, enhancing therapeutic activities in inpatient units, increasing capacity and responsiveness of the Mental Health line and expanding virtual mental health services

Overall health spending accounted for one third of the total NSW Budget, Health Minister Brad Hazzard said.

It included $66 million over three years beginning in 2021-22 to fund additional specialist mental health clinicians. Almost $56 million over four years will go to end of life and palliative care, including 5000 additional non-clinical End of Life Support, specialist allied health professionals, education and training, and bereavement and psychosocial support services.

Almost $50 million in 2020-2021 will fund access to lifesaving cell and gene therapies, including CAR T-cell therapy for children and young adults with acute lymphoblastic leukaemia, adults with diffuse large B-cell lymphoma, as well as gene therapy services for blinding eye disease and children with spinal muscular atrophy, and monoclonal antibody therapy for children with neuroblastoma.

A $17 million-pilot program will provide in-home care for pregnant women suffering from hyperemesis gravidarum (severe morning sickness), and Tresillian and Karitane will receive more than $10 million over four years to extend virtual residential parenting services.

There is $10 million over four years to plan and undertake a NSW stroke ambulance pilot project geared towards rapid diagnosis and treatment of strokes.

The governments hospital building boom over the past several years continues. Treasurer Dominic Perrottet said the 29 upgraded hospitals and health facilities announced before the 2019 election would be under way before March 2023.

The Australian Medical Association NSW said it was concerned by the state government's continued emphasis on funding health infrastructure over current funding for staffing and resourcing.

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"Hospitals and healthcare staff are struggling to meet patient demand," AMA NSW President Dr Danielle McMullen said.

The recent concerns raised about resourcing and services at Blacktown Hospital highlight the importance of funding all hospitals appropriately," she said.

Dr McMullen was also concerned funding to fast track elective surgeries wont move the needle enough to improve patient access.

We can see that access is deteriorating and wait times are getting worse," she said. "Patients are waiting more than a year for elective surgery in some cases and we know these figures only tell half the story.

Get our Coronavirus Update newsletter for the day's crucial developments and the numbers you need to know. Sign up toThe Sydney Morning Herald'snewsletterhereandThe Age'shere.

Kate Aubusson is Health Editor of The Sydney Morning Herald.

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$30 billion to fight COVID-19 over next five years - Sydney Morning Herald

Community Cord Blood Banking saves life of child with aplastic anaemia – The Hindu

Community Cord Blood Banking, a stem cell banking initiative introduced by LifeCell in 2017, has helped save the life of a seven-year-old girl from Nashik in Maharashtra who was suffering from aplastic anaemia, a rare and serious blood disorder.

In a major breakthrough, a team of senior doctors from LOTUS Institute of Haematology, Oncology and Bone Marrow Transplantation, recently conducted Indias first dual cord blood transplant through an unrelated donor using Community Stem Cell Banking. People familiar with the development said the transplant was challenging because no apt bone marrow donors were available and the cost of retrieval of matching units from public cord blood banks would have been high.

The girls parents, as members of LifeCell Community Bank, placed a request for two matching cord blood units after the childs sibling was found to be only a 50% (4/8) match. Two high-quality matches (7/8) were found in the registry, which fulfilled the requirement for umbilical cord blood transplantation. The parents could withdraw the matched units at no extra expense, which would have cost around 45 lakh per unit.

Mayur Abhaya, MD, LifeCell International said, The purpose of Community Cord Blood Banking is to ensure easy and rapid access to stem cells for every Indian without the hurdles of public and private banking models. While stem cells from the umbilical cord blood can be procured from global public banks, the probability of finding a match for a patient of Indian origin is less than 10% because of the low inventory of available units plus the big issue of donor dropouts.

Mr. Abhaya said, Luckily, since the family was a part of LifeCells community banking programme, they could gain quick, free access to the huge inventory of over 50,000 qualified and consented units available at LifeCell, which provides greater than 97% probability of finding a match.

In majority of blood-related disorders treatable by transplants, patients own stem cells are not suitable. Hence, the best donor is a close family member, usually a sibling. However, in this case, there was only a 50% match with the sibling, thus needing a match from an unrelated donor, LifeCell said in a statement. It said while a regular stem cell transplant requires a dose of 25 million cells per kg of the patients weight, for aplastic anaemia, the recommended minimum dose is 40 million cells per kg, which is not easy to find.

The community banking model made it possible and the child received a timely transplant with an encouraging prognosis. Just 18 days after the transplant, white blood cells were completely engrafted, and platelets and red blood cell production also increased drastically, the statement added.

Dr. Pritesh Junagade, director, LOTUS Hospital, expressed surprise that the retrieval process for two cord blood units was smooth and at no additional cost to the patient as compared to other banking models.

Tasneem Bohari, the childs father, said: It was two years ago that my daughter was diagnosed with aplastic anaemia. At the time of diagnosis, the doctors had suggested she would need a stem cell transplant eventually and it would be the best possible treatment in the future.

The family did research and made enquiries about which stem cell bank to opt for as they were expecting their second child. It was during this time that their friends and relatives suggested LifeCell to them. Their doctor also suggested that they could go ahead and preserve their babys stem cell with LifeCell.

At the time of preservation, we didnt have much idea about Community Stem Cell Banking and its benefits, but today we are happy to associate with LifeCell, who have helped my daughter lead a quality life through cord blood transplant, Mr. Bohari said.

Community Cord Blood Banking allows sharing of preserved umbilical cord stem cells from a common pool amongst the members of the community. The model offers greater and easier access to donor stem cells, unlimited retrievals at the cost of one enrolment, and a higher probability for finding a close match for potentially life-saving treatments.

This facility ensures complete protection to the child, siblings, parents, and maternal and paternal grandparents from more than 80 disorders treatable by stem cells.

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Community Cord Blood Banking saves life of child with aplastic anaemia - The Hindu

Arya Lloyd: Father launches global search for blood stem cell donor to save his 12-year-old daughter – Sky News

A surgeon has launched a global search for a blood stem cell donor to save the life of his seriously ill 12-year-old daughter.

Arya Lloyd first complained of stomach pains in May this year, and initially her parents thought they were general growing pains.

But when the pains persisted, Arya was referred to St Mary's Hospital in Paddington, London, and was diagnosed with the blood disorder aplastic anaemia.

Doctors say her best chance of survival is through a blood stem transplant.

Her parents Geraint Lloyd, 45, a consultant general surgeon at the Lister Hospital in Stevenage, and dentist Brundha Lloyd, 47, have been told they would only be a 50% match at best and that Arya needs a 10/10 match.

Ordinarily the best match would be from a sibling, but she is an only child so her best hope now rests with a stranger.

Mr Lloyd, from Cambridge, said: "Our world was turned on its head when we were given Arya's devastating diagnosis.

"It is with us always, and we're doing all we can to provide her with a second chance of life.

"I am a surgeon who has spent half my life looking after people with serious medical problems and cancer, but nothing prepares you for this.

"The world is a very different place now we know Arya is so unwell."

The family is working with international blood cancer charity DKMS in search of a donor.

Arya's mixed heritage - being Indian and Caucasian - makes the search for a donor more challenging.

Mrs Lloyd has family in America and India, and DKMS has branches in both countries, so a global search to find Arya her match is on.

Although the UK has a diverse population, patients from a black, Asian or other minority background have a 20% chance of finding the best possible stem cell donor match, compared to 69% from northern European backgrounds, DKMS said.

Mr Lloyd said: "We're at the mercy of others right now. We need their support."

DKMS has reported a steep decline in new donors coming forward since March due to COVID-19.

EastEnders actor Priya Davdra is working with DKMS to encourage more people, particularly those from Asian communities, to sign up as potential blood stem cell donors.

"It broke my heart when I heard about Arya's situation," she said.

"To think what she and her family must be going through is just so awful."

She has signed up as a potential donor and urged others to do so.

DKMS is seeking potential blood stem cell donors from all backgrounds.

If you are aged between 17 and 55 and in good general health, you can support Arya and the other 2,000 people in need of a lifesaving transplant by registering online at dkms.org.uk/en/arya for a home swab kit

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Arya Lloyd: Father launches global search for blood stem cell donor to save his 12-year-old daughter - Sky News

Blood Cancer: Science Reveal Five Easily Missed Signs of Leukemia – Science Times

Experts diagnose someone with a blood cancerapproximately every three minutes in the United States. Every year, new blood cancer reports account for10 percent of new diagnoses of cancer.

There are typically three separate types of blood cancers, according toExpress.co.uk. These include leukemia, lymphoma, and myeloma. Signs and symptoms vary based on the form of blood cancer an individual has.

Major factors in leukemia survival rates include early diagnosis and management. Read on to find out more about some of the signs of early blood cancer that you can never miss.

(Photo : Dan Kitwood/Getty Images/Cancer Research UK) CAMBRIDGE, UNITED KINGDOM - DECEMBER 09: A fridge of chemical solutions which contain nutrients that are needed to 'feed' cells and keep them alive for laboratory experiments, at the Cancer Research UK Cambridge Institute on December 9, 2014 in Cambridge, England. Cancer Research UK is the world's leading cancer charity dedicated to saving lives through research. Its vision is to bring forward the day when all cancers are cured. They have saved millions of lives by discovering new ways to prevent, diagnose and treat cancer, and as such the survival rate in the UK has doubled in the last 40 years. Cancer Research UK funds over 4,000 scientists, doctors and nurses across the UK, more than 33,000 patients who join clinical trials each year and a further 40,000 volunteers that give their time to support the work.

According toHematology.org, most blood cancers begin in the bone marrow - where blood is made. These cancers disrupt the development and work of your blood. The stem cells transform into three types of blood cells-white, red, or platelets in the bone marrow.

When anyone has blood cancer, and irregular blood cell's development influences the regular output of blood cells. These cancer cells inhibit the regular functions of your blood such as preventing excessive bleeding or combating diseases. There are three major types of tumors in the blood: leukemia, lymphoma, and myeloma.

Leukemia is a disease that induces the massive development of irregular white blood cells in your blood marrow. This stops bacteria from being combated by the body. These cells often hinder platelets and red blood cells from being formed by the bone marrow.

Plasma cell cancer is myeloma. The antibodies in your body are produced by these white blood cells to combat and resist illnesses and diseases. This cancer can disrupt the immune system of your body and render you susceptible to infection.

Lymphoma hinders the lymphatic function that generates immune cells and removes the body from surplus fluids. Abnormal lymphocytes, along with other cells, can accumulate and gather in the lymph nodes. The body's immune system is weakened by these cancerous cells.

Blood cancer signs differ, like leukemia. Here are certain signs of blood cancer that you can look out for. Many of these signs may sound like the flu and maybe simple to ignore.

If the body produces leukemia, blood cells are destroyed by the disease, so it is impossible for your body to produce safe blood cells. You can experience anemia, and light skin is one of the major signs of anemia. Also, your hands can feel cold to the touch.

A typical symptom in certain diseases is exhaustion. You can see the doctor if you feel more worn out than usual and note a drastic difference in your energy.

Your blood cells aid the functioning of the immune system. The body's immune system does not normally work when certain cells are unhealthy, leading you to get sick more frequently. Frequent fevers and pneumonia are some of the most prominent first signs of leukemia.

You can also keep an eye on any shortness of breath if you are feeling energy depleted. You can take care if you feel short of breath any more quickly during physical exercise.

You can bleed more than usual because the body does not produce enough platelets. You might even more often get a bloody nose. Other modifications connected to your blood that you can look out for include:

No one is sure of what induces leukemia or other cancers of the blood, and there is no means of stopping it. Many factors in the environment, including smoking, pollution, and radiation, may lead to this disease's growth. The past of the family may also play a part in your chance of leukemia.

ALSO READ: Coronavirus Survivors Twice as Likely to Develop Mental Disorders - Study

Check out more news and information on Medicine and Healthon Science Times.

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Blood Cancer: Science Reveal Five Easily Missed Signs of Leukemia - Science Times

BioRestorative Therapies Emerges from Chapter 11 Reorganization Other OTC:BRTX – GlobeNewswire

November 20, 2020 07:00 ET | Source: BioRestorative Therapies, Inc.

MELVILLE, N.Y., Nov. 20, 2020 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (BioRestorative or the Company) (OTC: BRTX), a life sciences company focused on stem cell-based therapies, announced today that its amended joint plan of reorganization has become effective and it has emerged from Chapter 11 reorganization. Pursuant to the confirmed plan of reorganization, the Company has received $3,848,000 in financing. The confirmed plan of reorganization also provides for additional funding, subject to certain conditions, of $3,500,000 less the sum of the debtor-in-possession financing provided to the Company during the reorganization (approximately $1,227,000) and the costs incurred by the debtor-in-possession lender.

In connection with the reorganization, Lance Alstodt has been appointed the Companys President, Chief Executive Officer and Chairman of the Board. Mr. Alstodt said, This process has been a long and challenging journey for the Company. Im inspired by the great resolve and execution from our employees, professionals and investors. We are very pleased that all requirements have been met for us to emerge. Allowed creditor claims have been fully satisfied and, as importantly, our equity holders have retained their shares in this exciting new opportunity. We were able to preserve all of our intellectual property assets and look forward to initiating our Phase 2 clinical trial.

Based upon the Companys emergence from Chapter 11 reorganization, FINRA has removed the Q at the end of its trading symbol. Shareholders do not need to exchange their shares for new shares.

About BioRestorative Therapies, Inc.

BioRestorative Therapies, Inc. (www.biorestorative.com) develops therapeutic products using cell and tissue protocols, primarily involving adult stem cells. Our two core programs, as described below, relate to the treatment of disc/spine disease and metabolic disorders:

Disc/Spine Program (brtxDISC): Our lead cell therapy candidate, BRTX-100, is a product formulated from autologous (or a persons own) cultured mesenchymal stem cells collected from the patients bone marrow. We intend that the product will be used for the non-surgical treatment of painful lumbosacral disc disorders. The BRTX-100 production process utilizes proprietary technology and involves collecting a patients bone marrow, isolating and culturing stem cells from the bone marrow and cryopreserving the cells. In an outpatient procedure, BRTX-100 is to be injected by a physician into the patients damaged disc. The treatment is intended for patients whose pain has not been alleviated by non-invasive procedures and who potentially face the prospect of surgery. We have received authorization from the Food and Drug Administration to commence a Phase 2 clinical trial using BRTX-100 to treat persistent lower back pain due to painful degenerative discs.

Metabolic Program (ThermoStem): We are developing a cell-based therapy to target obesity and metabolic disorders using brown adipose (fat) derived stem cells to generate brown adipose tissue (BAT). BAT is intended to mimic naturally occurring brown adipose depots that regulate metabolic homeostasis in humans. Initial preclinical research indicates that increased amounts of brown fat in the body may be responsible for additional caloric burning as well as reduced glucose and lipid levels. Researchers have found that people with higher levels of brown fat may have a reduced risk for obesity and diabetes.

Forward-Looking Statements

This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events or results to differ materially from those projected in the forward-looking statements as a result of various factors and other risks, including, without limitation, those set forth in the Company's latest Form 10-K filed with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and the Company undertakes no obligation to update such statements.

CONTACT: Email: ir@biorestorative.com

BioRestorative Therapies, Inc.

Melville, New York, UNITED STATES

http://www.biorestorative.com

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