Stem Cell Clinic

How Hematopoietic Stem Cell Transplantation (HSCT) Market Will Dominate In Coming Years? Report Covering Products, Financial Information,…

By adminOctober 29, 2020Stell Cell Research

The Global Hematopoietic Stem Cell Transplantation (HSCT) Market report offers key insights into the worldwide Hematopoietic Stem Cell Transplantation (HSCT) market. It presents a holistic overview of the market, with an in-depth summary of the markets leading players. The report is inclusive of indispensable information related to the leading competitors in this business sector and carefully analyzes the micro- and macro-economic market trends. The latest report specializes in studying primary and secondary market drivers, market share, the leading market segments, and comprehensive geographical analysis. Vital information about the key market players and their key business strategies, such as mergers & acquisitions, collaborations, technological innovation, and trending business policies, is one of the key components of the report.

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The report covers extensive analysis of the key market players in the market, along with their business overview, expansion plans, and strategies. The key players studied in the report include:

China Cord Blood Corp, Pluristem Therapeutics Inc., CBR Systems Inc CellGenix Technologie Transfer GmbH, Cryo-Save AG Kite Pharma Inc., Regen Biopharma Inc., ViaCord Inc., BiolineRx, Cynata Therapeutics, Cesca Therapeutics Inc, Lonza Group Ltd, TiGenix N.V., Bluebird Bio, Cellular Dynamics International, and Escape Therapeutics Inc., among others.

Furthermore, our market analysts have drawn focus to the significant impact of the COVID-19 pandemic on the global Hematopoietic Stem Cell Transplantation (HSCT) market and its key segments and sub-segments. The grave aftereffects of the pandemic on the global economy, and subsequently, on this particular business sphere, have been enumerated in this section of the report. The report considers the key market-influencing parameters, delivering a detailed future impact assessment. The Hematopoietic Stem Cell Transplantation (HSCT) market has been devastated by the pandemic, which has culminated in drastic changes to the market dynamics and demand trends.

In market segmentation by types of Hematopoietic Stem Cell Transplantation (HSCT), the report covers-

In market segmentation by applications of the Hematopoietic Stem Cell Transplantation (HSCT), the report covers the following uses-

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Moreover, the research report thoroughly examines the size, share, and market volume of the Hematopoietic Stem Cell Transplantation (HSCT) industry in the historical years to forecast the same valuations over the forecast duration. It offers exhaustive SWOT analysis, Porters Five Forces analysis, feasibility analysis, and investment return analysis of the Hematopoietic Stem Cell Transplantation (HSCT) market, assessed using certain effective analytical tools. The report also provides strategic recommendations to market entrants to help them navigate around the entry-level barriers.

The global Hematopoietic Stem Cell Transplantation (HSCT) market is geographically categorized into:

The following timeline is considered for market estimation:

Historical Years: 2017-2018

Base Year: 2019

Estimated Year: 2020

Forecast Years: 2020-2027

Key Coverage of the Report:

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How Hematopoietic Stem Cell Transplantation (HSCT) Market Will Dominate In Coming Years? Report Covering Products, Financial Information,...

Hyperbaric Oxygen Therapy (HBOT)Market: Is Covid19 testing the healthcare industry? – PRnews Leader

By adminOctober 29, 2020Gene Therapy Clinics

The rise in prevalence of chronic diseases worldwide is propelling the global hyperbaric oxygen therapy market size growth says Fortune Business Insights in their new study. The study is titled Hyperbaric Oxygen Therapy (HBOT)Market Size, Share and Global Trend By Product (Monoplace oxygen chambers, Multiplace oxygen chambers, Topical oxygen chambers, Portable oxygen chambers), By Application (Decompression Sickness, Wound Healing, Infectious diseases, Gas Embolism, Carbon monoxide poisoning, Others), By End Users (Hospitals, Ambulatory care centers, Outpatient clinics, Standalone hyperbaric treatment centers) and Geography Forecast 2026.

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Hyperbaric Oxygen Therapy (HBOT)Market: Is Covid19 testing the healthcare industry? - PRnews Leader

The good news about breast cancer – The Gazette

By adminOctober 29, 2020Gene Therapy Clinics

By Maggie Ireland, for The Gazette

October as Breast Cancer Awareness Month shines a spotlight on the battle against breast cancer and the developments in diagnosing and treating the disease that inspire hope for the future.

Breast cancer remains very common. Its still the most common cancer in women, said Dr. Ingrid Lizarraga, a clinical associate professor of surgery and breast surgeon at the University of Iowa Hospitals and Clinics in Iowa City.

But it is no longer the most common cause of death for women it is now the second most common cause of cancer death for women after lung cancer. We know a lot

more about breast cancer than we ever did before. The vast majority of women who have breast cancer will do great.

Admittedly, a breast cancer prognosis largely depends on the type of breast cancer you have and the stage at which it is diagnosed. The good news is that the prognosis has improved considerably over the years.

Mortality rates are decreasing, thanks to improved screenings and improved treatment, said Dr. Rasa Buntinas, an oncologist at PCI in Cedar Rapids. At our cancer center, 80 percent of women are diagnosed at an early stage stage 0 or stage 1 and that means a better chance of survival.

More screening options have become available in recent years.

Mammograms are still what we recommend, Lizarraga said. 3-D mammograms have been around for about five years and can be really helpful for women with dense

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breasts. The recognition that breast density affects how you screen is important. Whole breast ultrasounds can also be useful.

For women with abnormal findings, a breast MRI is an option.

Discussing your personal risk factors with your doctor is the best way to determine what screenings are best for you.

The latest developments in genetic testing can further pinpoint specific risk factors.

Weve identified a set of genes that puts you at high risk for developing breast cancer, and we can test for this gene, Lizarraga said. The trick is to find those at risk who need the genetic testing. If you have concerns, talk to your doctor so they can assess your risk and give you better guidance on a screening regimen.

Today, the widely accepted recommendation is for most women to begin getting an annual mammogram at age 40.

If you have any risk factors at all, start at 40. But the latest you should start is at age 45. And you should screen every year, Lizarraga said. When youre younger, the odds are lower, but the stakes are higher.

In the past, all women were encouraged to do a monthly self-exam, but thats no longer the case.

Self-exams are no longer recommended, Buntinas said. They tended to lead to more testing and biopsies but really didnt improve outcomes. The recommendation now

is breast self-awareness. Be aware of how your breasts look and feel, and report changes to your doctor.

Lizarraga agrees that a woman should trust her instincts if she senses something is wrong.

You know your body better than anyone else, she said. It doesnt just have to be a lump it could be a different appearance of the skin or the nipple. Pay attention to how you feel and how you look, and advocate for yourself if you notice something.

Many developments have been made in treating breast cancer, particularly metastatic breast cancer, Buntinas said.

Were really getting a much better understanding of tumor biology, she said. Specific targets are being identified to better improve treatments and provide more of a personalized medicine approach. In practice, these treatments are really improving survival.

Its an exciting time in the treatment of breast cancer, Lizarraga said, because things pretty much change every day.

If a woman needs a mastectomy, we can give you a result that looks much closer to what your native breast looks like, she said. The attitude used to be that you shouldnt worry about how it looks, because you should be grateful you dont have cancer, but thats not accepted anymore.

Advancements also are being made in addressing the side effects of treatment, like lymphedema, the swelling of a womans arm or hand that can follow the removal of lymph nodes.

Weve gotten better at figuring out more effective techniques that result in less lymphedema, Lizarraga said. Were also now better able to save a womans breasts if she prefers to do that.

The biggest advances in treatment, however, have been in systemic therapies, or the use of drugs to reach cancer cells anywhere in the body, she said.

Almost all women with breast cancer will get some form of systemic treatment pills or therapy.

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Weve become increasingly targeted with treatment, Lizarraga said. We start by figuring out which type of breast cancer you have. We now have genomic tests, so we can test the DNA of the tumor itself to see how likely it is to recur. That actually allows us to figure out whether a woman will benefit from chemotherapy or not.

Thats huge because we can limit the toxic treatment when its not going to be beneficial.

Treatment is more targeted than ever.

We match severity of treatment to the severity of disease, Lizarraga said. Weve figured out how to make things more personal in a lot of cases, weve changed the timing of treatment. In the past, you often came in, had surgery and then began the next form of treatment, like chemotherapy or pills.

Now, we often provide treatment before surgery and then personalize what is needed next.

Lizarraga said women of all ages need to know breast cancer is common but treatable, as long as its caught early.

If you do have a family history, be sure to get evaluated to see if genetic testing is appropriate, she said.

And know that who treats you is important, too.

Get a second opinion make sure the person youre seeing is someone who knows specifically about breast cancer treatment and the latest developments. Advocate for

yourself.

Both doctors agree the prognosis for breast cancer patients is brighter than ever.

The outlook is very positive and hopeful for the future, Buntinas said.

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Coronavirus Outbreak: C-Arms Industry Fights Back with Well-defined Business Strategies – PRnews Leader

By adminOctober 29, 2020Gene Therapy Clinics

As chronic diseases become more widespread, the global C-arms market is expected to grow considerably during the forecast period. Fortune Business Insights shares valuable market analysis in its report, titled C-arms Market Size, Share and Global Trend By Size (Mini C-arms, Compact C-arms, Full-size C-arms, Others), By Application (Cardiology, Urology, Neurology, Orthopaedics, Others), By Type (Fixed, Mobile), By Technology (Image Intensifiers, Flat Panel Detectors), By End User (Hospitals, Specialty Clinics, Diagnostics & Imaging Centers, Others), and Geography Forecast till 2026. The report also incorporates a comprehensive evaluation of emerging market trends and factors that will impact the market.

The report covers:

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Leading Players operating in the C-Arms Market are:

Key players are involved in mergers and acquisition to strengthen their market position. Owing to increasing competition frequent innovations are taking place in the market. Some of the companies operating the industry are:

Segmentation of the Global C-arms Market

By Size

By Application

By Type

By Technology

By End User

By Geography

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Retinitis Pigmentosa (Retinitis) Market Analysis by 24 Key Players, Types, Applications and Growth Opportunities to 2025 – The Think Curiouser

By adminOctober 29, 2020Gene Therapy Clinics

The market study on the global Retinitis Pigmentosa (Retinitis) market will encompass the entire ecosystem of the industry, covering major regions namely North America, Europe, Asia Pacific, South America, Middle East & Africa, and the major countries falling under those regions.

Firstly, the Retinitis Pigmentosa (Retinitis) Market Report provides a basic overview of the industry including definitions, classifications, applications and chain structure. The Retinitis Pigmentosa (Retinitis) market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status.

Key Players covered in this report are Sanofi, Amgen, Amarantus Bioscience Holdings, Acucela, Applied Genetic Technologies Corp, Asklepios BioPharmaceutical, Astellas Pharma, Caladrius Biosciences, Dompe Farmaceutici SpA, Dormant Projects, GenSight Biologics SA, Grupo Ferrer Internacional SA, ID Pharma, InFlectis BioScience, Ionis Pharmaceuticals, Mimetogen Pharmaceuticals, Ms Science Corp, Nanovector srl, Novartis AG, Novelion Therapeutics, ProQR Therapeutics, ReNeuron Group Plc, SanBio, Shire (Takeda Pharmaceutical), Spark Therapeutics.

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We Empower industries through current Market Trends, Business Intelligence, Qualitative & Quantitative Market Assessment and Solutions for the critical challenges

The Global Retinitis Pigmentosa (Retinitis) Market report focuses on global major leading industry players providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out.

The major types mentioned in the report are General Treatment, Traditional Chinese Medicine, Gene Therapy, The Surgical Treatment, Others and the applications covered in the report are Hospitals, Eye Clinics, Others, etc.

Major Points covered in this report are as below

The Retinitis Pigmentosa (Retinitis) industry development trends and marketing channels are analyzed. Finally, the feasibility of new investment projects are assessed and overall research conclusions offered.

With the tables and figures, the report provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

Development policies and plans, manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand figures, cost, price, revenue and gross margins.

The Retinitis Pigmentosa (Retinitis) Market report provides key statistics on the market status of the Retinitis Pigmentosa (Retinitis) manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.

We can also provide the customized data for separate regions like North America, United States, Canada, Mexico, Asia-Pacific, China, India, Japan, South Korea, Australia, Indonesia, Singapore, Rest of Asia-Pacific, Europe, Germany, France, UK, Italy, Spain, Russia, Rest of Europe, Central and South America, Brazil, Argentina, Rest of South America, Middle East and Africa, Saudi Arabia, Turkey, Rest of Middle East and Africa

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Major Points from the Table of Contents

1 Retinitis Pigmentosa (Retinitis) Market Overview

2 Global Retinitis Pigmentosa (Retinitis) Market Competition by Manufacturers

3 Global Retinitis Pigmentosa (Retinitis) Capacity, Production, Revenue (Value) by Region)

4 Global Retinitis Pigmentosa (Retinitis) Supply (Production), Consumption, Export, Import by Region

5 Global Retinitis Pigmentosa (Retinitis) Production, Revenue (Value), Price Trend by Type

6 Global Retinitis Pigmentosa (Retinitis) Market Analysis by Application

7 Global Retinitis Pigmentosa (Retinitis) Manufacturers Profiles/Analysis

8 Retinitis Pigmentosa (Retinitis) Manufacturing Cost Analysis

9 Industrial Chain, Sourcing Strategy and Downstream Buyers

10 Marketing Strategy Analysis, Distributors/Traders

11 Market Effect Factors Analysis

12 Global Retinitis Pigmentosa (Retinitis) Market Forecast

13 Research Findings and Conclusion

14 Appendix

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Retinitis Pigmentosa (Retinitis) Market Analysis by 24 Key Players, Types, Applications and Growth Opportunities to 2025 - The Think Curiouser

Global Induced Pluripotent Stem Cells (iPSCs) Market 2020 with COVID-19 After Effects Growth Drivers, Top Key Players, Industry Segments and Forecast…

By adminOctober 29, 2020Induced Pluripotent Stem Cells

The research document entitled Global Induced Pluripotent Stem Cells (iPSCs) Market 2020 by Company, Type and Application, Forecast to 2025 by MarketsandResearch.biz covers a host of metrics like supply-demand ratio, market frequency, market trends, dominant players of market driving factors, challenges, future prospects contains a forecast of 2020 and ending 2025. The report reveals the key elements influencing the market, the constraints, and the difficulties that could stop the market development. The report focuses on defining, describing, and analyzing the market competition landscape, market share, and development plans in future years. It sheds light on the key segments expected to dominate the market such as product type, application, and regions.

Market Dynamics:

The report explains an evaluation of the restraints, drivers and presents room for strategic planning. Factors that overshadow the global Induced Pluripotent Stem Cells (iPSCs) market growth are pivotal as they can be understood to compose different bends for getting hold of profitable opportunities. The regional segmentation has been analyzed in terms of business opportunities, demand & supply, and revenue generation potential. It also encompasses the analysis of the technical barriers, other issues, and cost-effectiveness affecting the market.

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NOTE: Our report highlights the major issues and hazards that companies might come across due to the unprecedented outbreak of COVID-19.

Then our industry analysts project the supply chains, market share, growth opportunities, market sizing, cost, applications, technologies, import & export, companies. The report provides a detailed overview of the supplier landscape, combative analysis, and key market strategies to gain a global Induced Pluripotent Stem Cells (iPSCs) market outlook, market trend, market forecast, market demand, market sales & price on competing companies. The region and segment that is expected to witness the fastest growth as well as to dominate the market has been indicated in the report. This research report recognizes the industrial base, productivity, manufacturers, strengths, recent trends, features.

Key players profiled in the global Induced Pluripotent Stem Cells (iPSCs) market include: Fujifilm Holding Corporation (CDI), ReproCELL, Astellas Pharma Inc, Ncardia, Cell Inspire Biotechnology, Sumitomo Dainippon Pharma, Pluricell Biotech, Fate Therapeutics, Inc

In market segmentation by types, the report covers: Human iPSCs, Mouse iPSCs

In market segmentation by applications, the report covers the following uses: Academic Research, Drug Development and Discovery, Toxicity Screening, Regenerative Medicine, Others

The report explores Induced Pluripotent Stem Cells (iPSCs) business policies, trading, market channels, market volume, providers of raw material and customer data, demand & supply ratio. Apart from that, geographic division relies on North America (United States, Canada and Mexico), Europe (Germany, France, United Kingdom, Russia and Italy), Asia-Pacific (China, Japan, Korea, India, Southeast Asia and Australia), South America (Brazil, Argentina), Middle East & Africa (Saudi Arabia, UAE, Egypt and South Africa).

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Global Induced Pluripotent Stem Cells (iPSCs) Market 2020 with COVID-19 After Effects Growth Drivers, Top Key Players, Industry Segments and Forecast...

Induced Pluripotent Stem Cells (iPSCs) Market 2019 | How The Industry Will Witness Substantial Growth In The Upcoming Years | Exclusive Report By…

By adminOctober 29, 2020Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells (iPSCs) Market Forecast 2020-2026

The Global Induced Pluripotent Stem Cells (iPSCs) Market research report provides and in-depth analysis on industry- and economy-wide database for business management that could potentially offer development and profitability for players in this market. This is a latest report, covering the current COVID-19 impact on the market. The pandemic of Coronavirus (COVID-19) has affected every aspect of life globally. This has brought along several changes in market conditions. The rapidly changing market scenario and initial and future assessment of the impact is covered in the report. It offers critical information pertaining to the current and future growth of the market. It focuses on technologies, volume, and materials in, and in-depth analysis of the market. The study has a section dedicated for profiling key companies in the market along with the market shares they hold.

The report consists of trends that are anticipated to impact the growth of the Induced Pluripotent Stem Cells (iPSCs) Market during the forecast period between 2020 and 2026. Evaluation of these trends is included in the report, along with their product innovations.

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The Report Covers the Following Companies: Fujifilm Holding Corporation (CDI) Ncardia Sumitomo Dainippon Pharma Astellas Pharma Inc Fate Therapeutics, Inc Pluricell Biotech Cell Inspire Biotechnology ReproCELL Induced Pluripotent Stem Cells (iPSCs

By Types: Human iPSCs Mouse iPSCs Human iPSCs had a market share of 89% in 2018, followed by Mouse iPSCs. Induced Pluripotent Stem Cells (iPSCs

By Applications: Academic Research Drug Development and Discovery Toxicity Screening Regenerative Medicine

Furthermore, the report includes growth rate of the global market, consumption tables, facts, figures, and statistics of key segments.

By Regions:

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Years Considered to Estimate the Market Size: History Year: 2015-2019 Base Year: 2019 Estimated Year: 2020 Forecast Year: 2020-2026

Important Facts about Induced Pluripotent Stem Cells (iPSCs) Market Report:

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Global Induced Pluripotent Stem Cells Market Analysis by Size: 2025, Impact of Covid-19 on Industry Chain, Market Growth, Drivers | Business Overview…

By adminOctober 29, 2020Induced Pluripotent Stem Cells

BrainStorm Cell Therapeutics Inc.

The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Induced Pluripotent Stem Cells in 2020. This report helps users in comprehending the key product segments and their future developments. And also provide the perspectives for the impact of COVID-19 from the long and short term. The Induced Pluripotent Stem Cells market declared the influence of the crisis on the industry chain, especially for marketing channels. Timely update the industry economic revitalization plan of the country-wise government.

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The Induced Pluripotent Stem Cells market analysis and forecast by types, by applications, by regions, SWOT analysis which is included the industry growth rate, market constraints and challenges, characteristics and business expansion plans for the upcoming years.

on the basis of types, the Induced Pluripotent Stem Cells market from 2015 to 2025 is primarily split into:

The report assesses the key opportunities in the market and the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2025).

Geographical Segmentation:

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Years considered for this report:

Key questions answered in this report:

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Detailed TOC of Induced Pluripotent Stem Cells Market Report Growth, Challenges and Forecast to 2020-2025:

1 COVID-19 Impact on Induced Pluripotent Stem Cells Market Overview

1.1 Product Definition and Market Characteristics

1.2 Global Induced Pluripotent Stem Cells Market Size

1.3 Induced Pluripotent Stem Cells Market Segmentation

1.4 Global Macroeconomic Analysis

1.5 SWOT Analysis

2 COVID-19 Impact on Induced Pluripotent Stem Cells Market Dynamics

2.1 Induced Pluripotent Stem Cells Market Drivers

2.2 Induced Pluripotent Stem Cells Market Constraints and Challenges

2.3 Emerging Market Trends

2.4 Impact of COVID-19

2.4.1 Short-term Impact

2.4.2 Long-term Impact

3 Associated Industry Assessment

3.1 Supply Chain Analysis

3.2 Industry Active Participants

3.2.1 Suppliers of Raw Materials

3.2.2 Key Distributors/Retailers

3.3 Alternative Analysis

3.4 The Impact of Covid-19 From the Perspective of Industry Chain

Continued

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Global Induced Pluripotent Stem Cells Market Analysis by Size: 2025, Impact of Covid-19 on Industry Chain, Market Growth, Drivers | Business Overview...

The Induced Pluripotent Stem Cells Market To Witness A Major Breakthrough In The Form Of A Double-Digit CAGR Of 7% – KYT24

By adminOctober 29, 2020Induced Pluripotent Stem Cells

Market Report Summary

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Read Full Press Release Below

The healthcare industry has been focusing on excessive research and development in the last couple of decades to ensure that the need to address issues related to the availability of drugs and treatments for certain chronic diseases is effectively met. Healthcare researchers and scientists at the Li Ka Shing Faculty of Medicine of the Hong Kong University have successfully demonstrated the utilization of human induced pluripotent stem cells or hiPSCs from the skin cells of the patient for testing therapeutic drugs.

The success of this research suggests that scientists have crossed one more hurdle towards using stem cells in precision medicine for the treatment of patients suffering from sporadic hereditary diseases. iPSCs are the new generation approach towards the prevention and treatment of diseases that takes into account patients on an individual basis considering their genetic makeup, lifestyle, and environment. Along with the capacity to transform into different body cell types and same genetic composition of the donors, hiPSCs have surfaced as a promising cell source to screen and test drugs.

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Company Profile

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In the present research, hiPSC was synthesized from patients suffering from a rare form of hereditary cardiomyopathy owing to the mutations in Lamin A/C related cardiomyopathy in their distinct families. The affected individuals suffer from sudden death, stroke, and heart failure at a very young age. As on date, there is no exact treatment available for this condition.

This team in Hong Kong tested a drug named PTC124 to suppress specific genetic mutations in other genetic diseases into the iPSC transformed heart muscle cells. While this technology is being considered as a breakthrough in clinical stem cell research, the team at Hong Kong University is collaborating with drug companies regarding its clinical application.

The unique properties of iPS cells provides extensive potential to several biopharmaceutical applications. iPSCs are also used in toxicology testing, high throughput, disease modeling, and target identification. This type of stem cell has the potential to transform drug discovery by offering physiologically relevant cells for tool discovery, compound identification, and target validation.

A new report by Persistence Market Research (PMR) states that the globalinduced pluripotent stem or iPS cell marketis expected to witness a strong CAGR of 7.0% from 2018 to 2026. In 2017, the market was worth US$ 1,254.0 Mn and is expected to reach US$ 2,299.5 Mn by the end of the forecast period in 2026.

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Customization to be the Key Focus of Market Players

Due to the evolving needs of the research community, the demand for specialized cell lines have increased to a certain point where most vendors offering these products cannot depend solely on sales from catalog products. The quality of the products and lead time can determine the choices while requesting custom solutions at the same time. Companies usually focus on establishing a strong distribution network for enabling products to reach customers from the manufacturing units in a short time period.

Entry of Multiple Small Players to be Witnessed in the Coming Years

Several leading players have their presence in the global market; however, many specialized products and services are provided by small and regional vendors. By targeting their marketing strategies towards research institutes and small biotechnology companies, these new players have swiftly established their presence in the market.

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Emulate Signs Collaborative Agreement with the FDA to Apply Lung-Chip to Evaluate Safety of COVID-19 Vaccines and Protective Immunity Against…

By adminOctober 29, 2020Induced Pluripotent Stem Cells

Oct. 29, 2020 11:00 UTC

Agency-wide CRADA agreement also includes studies with Brain-Chip in Alzheimers disease, Intestine-Chip in microbiome health, and Liver-Chip in individualized toxicity responses

BOSTON--(BUSINESS WIRE)-- Emulate, Inc.. announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the U.S. Food and Drug Administration (FDA) to enable multiple studies across FDA offices in priority research areas, including programs to evaluate COVID-19 vaccines and understand human immune response against SARS-CoV-2, the virus that causes COVID-19.

Under the CRADA, the FDA will use a range of Organ-Chips from Emulate to study the safety, efficacy, and mechanisms of drugs regulated by the FDA. The initial studies use Organ-Chipswhich are able to recreate the natural physiology of specific human tissues and organsin areas where conventional cell culture and animal-based testing methods have limitations in reflecting human biology and disease mechanisms that are not yet understood, such as Alzheimers disease and COVID-19. This new CRADA agreement follows the successful completion of the first Emulate CRADA with the FDA initiated in 2017 that focused on toxicity studies using the Liver-Chip.

We are excited to continue our relationship and collaborative work with the FDA, combining Emulates expertise with leading researchers at the FDA to explore how our Organ-Chips can lead to new ways to improve standards, understand disease and drug mechanisms, and better evaluate the safety and efficacy of products for human use, said Jim Corbett, Chief Executive Officer of Emulate. The FDA is a valued stakeholder and strategic collaborator as our Human Emulation System continues to be adopted for the evaluation of pharmaceuticals and other products that are reviewed and approved by regulatory authorities to protect and improve human health.

The FDA has a long history of supporting efforts to develop new regulatory tools that have the potential to refine, reduce, or replace animal testing, said FDA Chief Scientist, Rear Admiral Denise Hinton. Our deep engagement in research collaborations like this one is crucial to advancing technologies like Organ-Chips that may help identify toxicity, efficacy, and disease susceptibility earlier in product development. A robust commitment to science is at the core of our public health mission and helping to facilitate advancements in regulatory science reflects our dedication to fostering the development of critical medical products to address public health threats like COVID-19.

COVID-19 Lung-Chip study to advance understanding of protective immunity and vaccine safety

The Lung-Chip study, which will be led by the FDAs Center for Biologics Evaluation and Research (CBER), aims to address one of the most important questions regarding protective immunity against SARSCoV-2: why individuals experience a wide spectrum of disease severity and what constitutes a real protection against future infection. The Emulate human Lung-Chip offers the unique functionality of mechanical strain and dynamic fluid flow to recreate the microenvironment found in the human lung. Highlights of the study objectives include:

We are enthusiastic to collaborate with essential regulatory partners like the FDA to apply our unique Organ-on-Chips platform to advance the understanding of the SARS-CoV-2 virus and to do our part in bringing safe and effective COVID-19 vaccines and treatments to the world, Lorna Ewart, PhD, Executive Vice President, Scientific Liaison of Emulate. There is a time-sensitive need to contribute our technology and expertise to support the FDA with their COVID-19 response, and over time, there will continue to be a need to understand longer-term protective immunity and vaccine safety.

Studies with multiple Organ-Chips support areas of emerging disease biology and drug mechanisms

The CRADA is led by the FDAs Office of the Chief Scientist, allowing for studies across FDA offices with Organ-Chips from Emulate. Through the CRADA, multiple installations of the Human Emulation System will be established in several FDA laboratories.

In addition to the COVID-19 study, other projects that will be initiated under the CRADA include:

More information about how Emulate is enabling COVID-19 research can be found in the companys latest blog post.

About Emulate, Inc.

Emulate Inc. is a privately held company that creates living products for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System includes three components: Zo Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and diseaseoffering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Each of Emulates proprietary Organ-Chipsincluding the liver, intestine, and kidneycontains tiny hollow channels lined with tens of thousands of living human cells and tissues and is approximately the size of an AA battery. An Organ-Chip is a living, microengineered environment that recreates the natural physiology and mechanical forces that cells experience within the human body. Our founding team pioneered the Organs-on-Chips technology at the Wyss Institute for Biologically Inspired Engineering at Harvard University. Emulate holds the worldwide exclusive license from Harvard University to a robust and broad intellectual property portfolio for the Organs-on-Chips technology and related systems. For more information, please visit http://www.emulatebio.com.

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