Stem Cell Clinic

Blood cell separation market Share 2020 In-Depth Analysis of Industry Growth Trends & Forecast up to 2027 – The Daily Chronicle

By Stell Cell Research

Global Blood cell separation market 2020 industry research report gives Advancement strategies and plans are talked about just as assembling procedures and cost structures are likewise examined. blood cell separation Market Report states import/send out utilization, organic market Figures, cost, value, income and gross edges. This report also studies the global blood cell separation market status, competition landscape, market share, growth rate, future trends, market drivers, opportunities and challenges, sales channels and distributors. Regionally, this report categorizes the production, apparent consumption, export and import of blood cell separation in North America, Europe, China, Japan, Southeast Asia and India.

The Global blood cell separation market 2020 research provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Global blood cell separation Market Share analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analysed. This report also states import/export consumption, supply and demand Figures, cost, price, revenue and gross margins. For each manufacturer covered, this report analyses their blood cell separation manufacturing sites, capacity, production, ex-factory price, revenue and market share in global market.

Highlights of the Report:

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The global blood cell separation market is anticipated to rise at a considerable rate during the forecast period, between 2020 and 2026. In 2020, the market was growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

blood cell separation Market Report states import/send out utilization, organic market Figures, cost, value, income and gross edges. Research gives an outline of the business with orders, applications and industry chain structure. blood cell separation Market Report additionally gives information to the global markets including advancement patterns, aggressive scene examination, and key districts improvement status. Research gives an outline of the business with orders, applications and industry chain structure. blood cell separation Market Report additionally gives information to the global markets including advancement patterns, aggressive scene examination, and key districts improvement status.

Global blood cell separation Market Report 2020 provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

Frequently Asked Questions:

What is the scope of the report?

This market study covers the global and regional market with an in-depth analysis of the overall growth prospects in the market. Furthermore, it sheds light on the comprehensive competitive landscape of the global market. The report further offers a dashboard overview of leading companies encompassing their successful marketing strategies, market contribution, recent developments in both historic and present contexts.

An Overview of the Impact of COVID-19 on this Market:

The emergence of COVID-19 has brought the world to a standstill. We understand that this health crisis has brought an unprecedented impact on businesses across industries. However, this too shall pass. Rising support from governments and several companies can help in the fight against this highly contagious disease. There are some industries that are struggling and some are thriving. Overall, almost every sector is anticipated to be impacted by the pandemic.

We are taking continuous efforts to help your business sustain and grow during COVID-19 pandemics. Based on our experience and expertise, we will offer you an impact analysis of coronavirus outbreak across industries to help you prepare for the future.

To get the short-term and long-term impact of COVID-19 on this Market.

Please visit: https://www.fortunebusinessinsights.com/blood-cell-separation-market-103347

Regional Analysis:

The global blood cell separation market is expected to be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is anticipated to lead the global blood cell separation market due to an increasing prevalence of chronic disorders (cancer, cardiovascular diseases) in the U.S. According to the National Cancer Institute, about 1,735,350 new cancer cases were reported in 2018 in United States. Also, the availability of improved healthcare facilities and research and development in blood cell separation are responsible factors for its dominance. Europe is likely to have substantial market growth throughout the forecast period owing to the rising geriatric population, and rising prevalence of chronic disorders. Asia Pacific and Latin America are expected to register fast market growth during the forecast period due to the increasing number of chronic disorders, and rising awareness about the blood cell separation technologies among the people. On the other hand, the Middle East and Africa is projected to have a lucrative growth in blood cell separation market in the upcoming years owing to the lack of enough research and development activities in blood cell separation technologies due to limited availability of resources

List of TOP KEY PLAYERS in blood cell separation Market Report are

The major companies in the global blood cell separation market report includes Thermo Fisher Scientific Inc., Beckman Coulter, Inc., GENERAL ELECTRIC COMPANY, Merck KGaA, STEMCELL Technologies Inc.,Bio-Rad Laboratories, Inc., TERUMO BCT, INC. and other prominent players.

The Global blood cell separation market 2020 research provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Global blood cell separation Market Share analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analysed.

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Which market dynamics affect the business?

The report provides a detailed evaluation of the market by highlighting information on different aspects which include drivers, restraints, opportunities, and threats. This information can help stakeholders to make appropriate decisions before investing.

What are the key segments in the market?

By Product

o Reagents

o Kits

o Beads

o Centrifuges

o Flow Cytometers

o Filtration Systems

By Cell Type

ByTechnique

By Application

By End-User

By Geography

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Blood cell separation market Share 2020 In-Depth Analysis of Industry Growth Trends & Forecast up to 2027 - The Daily Chronicle

COVID-19 Outbreak- Global Circulating Tumor Cells Market 2019 analysis with Key Players, Applications, Trends and Forecasts by 2026 – The Daily…

By Stell Cell Research

The global Circulating Tumor Cells market focuses on encompassing major statistical evidence for the Circulating Tumor Cells industry as it offers our readers a value addition on guiding them in encountering the obstacles surrounding the market. A comprehensive addition of several factors such as global distribution, manufacturers, market size, and market factors that affect the global contributions are reported in the study. In addition the Circulating Tumor Cells study also shifts its attention with an in-depth competitive landscape, defined growth opportunities, market share coupled with product type and applications, key companies responsible for the production, and utilized strategies are also marked.

This intelligence and 2026 forecasts Circulating Tumor Cells industry report further exhibits a pattern of analyzing previous data sources gathered from reliable sources and sets a precedented growth trajectory for the Circulating Tumor Cells market. The report also focuses on a comprehensive market revenue streams along with growth patterns, analytics focused on market trends, and the overall volume of the market.

Moreover, the Circulating Tumor Cells report describes the market division based on various parameters and attributes that are based on geographical distribution, product types, applications, etc. The market segmentation clarifies further regional distribution for the Circulating Tumor Cells market, business trends, potential revenue sources, and upcoming market opportunities.

Download PDF Sample of Circulating Tumor Cells Market report @ https://hongchunresearch.com/request-a-sample/41494

Key players in the global Circulating Tumor Cells market covered in Chapter 4: Rarecells Diagnostics ApoCell Miltenyi Biotech Canopus Bioscience Nanostring Technologies IV Diagnostics Biocept Adnagen Ikonisys Vitatex Creatv Microtech

In Chapter 11 and 13.3, on the basis of types, the Circulating Tumor Cells market from 2015 to 2026 is primarily split into: Ex-Vivo Positive Selection In-Vivo Positive Selection Negative Selection Microchips & Single Spiral Micro Channel

In Chapter 12 and 13.4, on the basis of applications, the Circulating Tumor Cells market from 2015 to 2026 covers: Tumorigenesis Research EMT Biomarkers Development Cancer Stem Cell Research Others

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2026) of the following regions are covered in Chapter 5, 6, 7, 8, 9, 10, 13: North America (Covered in Chapter 6 and 13) United States Canada Mexico Europe (Covered in Chapter 7 and 13) Germany UK France Italy Spain Russia Others Asia-Pacific (Covered in Chapter 8 and 13) China Japan South Korea Australia India Southeast Asia Others Middle East and Africa (Covered in Chapter 9 and 13) Saudi Arabia UAE Egypt Nigeria South Africa Others South America (Covered in Chapter 10 and 13) Brazil Argentina Columbia Chile Others

The Circulating Tumor Cells market study further highlights the segmentation of the Circulating Tumor Cells industry on a global distribution. The report focuses on regions of North America, Europe, Asia, and the Rest of the World in terms of developing business trends, preferred market channels, investment feasibility, long term investments, and environmental analysis. The Circulating Tumor Cells report also calls attention to investigate product capacity, product price, profit streams, supply to demand ratio, production and market growth rate, and a projected growth forecast.

In addition, the Circulating Tumor Cells market study also covers several factors such as market status, key market trends, growth forecast, and growth opportunities. Furthermore, we analyze the challenges faced by the Circulating Tumor Cells market in terms of global and regional basis. The study also encompasses a number of opportunities and emerging trends which are considered by considering their impact on the global scale in acquiring a majority of the market share.

The study encompasses a variety of analytical resources such as SWOT analysis and Porters Five Forces analysis coupled with primary and secondary research methodologies. It covers all the bases surrounding the Circulating Tumor Cells industry as it explores the competitive nature of the market complete with a regional analysis.

Brief about Circulating Tumor Cells Market Report with [emailprotected]https://hongchunresearch.com/report/circulating-tumor-cells-market-41494

Some Point of Table of Content:

Chapter One: Report Overview

Chapter Two: Global Market Growth Trends

Chapter Three: Value Chain of Circulating Tumor Cells Market

Chapter Four: Players Profiles

Chapter Five: Global Circulating Tumor Cells Market Analysis by Regions

Chapter Six: North America Circulating Tumor Cells Market Analysis by Countries

Chapter Seven: Europe Circulating Tumor Cells Market Analysis by Countries

Chapter Eight: Asia-Pacific Circulating Tumor Cells Market Analysis by Countries

Chapter Nine: Middle East and Africa Circulating Tumor Cells Market Analysis by Countries

Chapter Ten: South America Circulating Tumor Cells Market Analysis by Countries

Chapter Eleven: Global Circulating Tumor Cells Market Segment by Types

Chapter Twelve: Global Circulating Tumor Cells Market Segment by Applications 12.1 Global Circulating Tumor Cells Sales, Revenue and Market Share by Applications (2015-2020) 12.1.1 Global Circulating Tumor Cells Sales and Market Share by Applications (2015-2020) 12.1.2 Global Circulating Tumor Cells Revenue and Market Share by Applications (2015-2020) 12.2 Tumorigenesis Research Sales, Revenue and Growth Rate (2015-2020) 12.3 EMT Biomarkers Development Sales, Revenue and Growth Rate (2015-2020) 12.4 Cancer Stem Cell Research Sales, Revenue and Growth Rate (2015-2020) 12.5 Others Sales, Revenue and Growth Rate (2015-2020)

Chapter Thirteen: Circulating Tumor Cells Market Forecast by Regions (2020-2026) continued

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NOTE: Our report does take into account the impact of coronavirus pandemic and dedicates qualitative as well as quantitative sections of information within the report that emphasizes the impact of COVID-19.

As this pandemic is ongoing and leading to dynamic shifts in stocks and businesses worldwide, we take into account the current condition and forecast the market data taking into consideration the micro and macroeconomic factors that will be affected by the pandemic.

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COVID-19 Outbreak- Global Circulating Tumor Cells Market 2019 analysis with Key Players, Applications, Trends and Forecasts by 2026 - The Daily...

Global Cancer Stem Cells Market 2020 with Impact of COVID-19 Outbreak | Thermo Fisher Scientific, Promocell, Bionomics, Abbvie – The Daily Chronicle

By Stell Cell Research

A new report published byMarketQuest.biztitled,Global Cancer Stem Cells Market 2020 by Company, Type and Application, Forecast to 2025offers an insightful evaluation of the market. The report presents exhaustive research details about the market highlighting the global Cancer Stem Cells market status, market size, value chain structure, and forecast details from 2020 to 2025 years. The report delivers a brief assessment related to the current and futuristic market conditions based on the gathered information on the market. Based on this the forecast analysis and future opportunities of the market have been predicted. In this latest report, the research analysts have tried to cover all the participants in the market. The market is classified based on product types and end-customer applications, key players, and topological zones.

NOTE: Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers post COVID-19 crisis. The report aims to provide an additional illustration of the latest scenario, economic slowdown, and COVID-19 impact on the overall industry.

DOWNLOAD FREE SAMPLE REPORT:https://www.marketquest.biz/sample-request/4425

The report focuses on important aspects such as in-depth analysis of the latest developments, industry drivers, challenges, with key company profiles and strategies of players. Then the report offers product classification, important concepts, and other industry-specific parameters. The study on the global Cancer Stem Cells market was carried out using an approach and hypotheses of standard and tailor-made research methodology. Along with that, the research report covers the major market players and their competitors along with their game-changing business strategic analysis. The report sheds light on the key factors according to present business strategies and events such as alliances, mergers and acquisitions, and new product launches. Readers will also find production, revenue, and average price shares by manufacturers.

The competitive vendors covered in this report are:Thermo Fisher Scientific, Promocell, Bionomics, Abbvie, Miltenyi Biotec, Merck Kgaa, Oncomed Pharmaceuticals, Stemline Therapeutics, Lonza, Macrogenics, Irvine Scientific, Biotime, Stemcell Technologies, Sino Biological

Regions/countries covered in the market report are:North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

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Additionally, The Report Includes Crucial Points:

Industry Preface: The first section of the research study touches on an overview of the global Cancer Stem Cells market, status and outlook, and product scope. Additionally, it provides highlights of key segments of the global market, i.e. regional, type, and application segments.

Industry Major Manufacturers Analysis: Global industry production sites and area served, product introduction, application and specification, production, revenue, ex-factory price and gross margin main business and markets served

Profiling Key Players: The report provides company profiling for a decent number of leading players in the global Cancer Stem Cells market.

Market Regional Outlook Analysis: This analysis totally based on two things one for regional production analysis and the other for regional consumption analysis.

The report demonstrates adequately identified most profit-generating growth hubs in the global Cancer Stem Cells market. The report then serves the observations and the comments from the research analysts and the market experts. Finally, the research study takes a critical look at the current status and future outlook for the consumption/sales of these products, by the end users and applications.

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Global Cancer Stem Cells Market 2020 with Impact of COVID-19 Outbreak | Thermo Fisher Scientific, Promocell, Bionomics, Abbvie - The Daily Chronicle

Automated Cell Cultures Market Size, Analytical Overview, Key Players, Growth Factors, Demand, Trends And Forecast to 2027 – The Daily Chronicle

By Stell Cell Research

HiMedia Laboratories

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Additionally, the report is furnished by the advanced analytical data from SWOT analysis, Porters Five Forces Analysis, Feasibility Analysis, and Investment Return Analysis. The report also provides a detailed analysis of the mergers, consolidations, acquisitions, partnerships, and government deals. Along with this, an in-depth analysis of current and emerging trends, opportunities, threats, limitations, entry-level barriers, restraints and drivers, and estimated market growth throughout the forecast period are offered in the report.

Market Breakdown:

The market breakdown provides market segmentation data based on the availability of the data and information. The market is segmented on the basis of types and applications.

Global Automated Cell Cultures Market, by Applications:

drug development stem cell research regenerative medicine cancer research

Global Automated Cell Cultures Market, by Type:

finite cell line cultures infinite cell line cultures

Global Automated Cell Cultures Market, by Consumables:

Media Sera Reagents

Global Automated Cell Cultures Market, by Instruments:

automated cell culture storage equipment automated cell culture vessels automated cell culture supporting instruments bioreactors

Global Automated Cell Cultures Market, by End User:

biotech companies research organizations academic institutes

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The report provides additional analysis about the key geographical segments of the Automated Cell Cultures Market and provides analysis about their current and previous share. Current and emerging trends, challenges, opportunities, and other influencing factors are presented in the report.

Regional analysis includes an in-depth study of the key geographical regions to gain a better understanding of the market and provide an accurate analysis. The regional analysis coversNorth America, Latin America, Europe, Asia-Pacific, and the Middle East & Africa.

Objectives of the Report:

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Automated Cell Cultures Market Size, Analytical Overview, Key Players, Growth Factors, Demand, Trends And Forecast to 2027 - The Daily Chronicle

Autologous Stem Cell and Non-Stem Cell Based Therapies MARKET 2020 |INDUSTRY ANALYSIS, SIZE, SHARE, TRENDS, MARKET DEMAND, GROWTH, OPPORTUNITIES AND…

By Stem Cell Medical Center

This report focuses on the Global Autologous Stem Cell and Non-Stem Cell Based Therapies Market trends, future forecasts, growth opportunities, key end-user industries, and market players. The objectives of the study are to present the key developments of the market across the globe.

The latest research report on Autologous Stem Cell and Non-Stem Cell Based Therapies market encompasses a detailed compilation of this industry, and a creditable overview of its segmentation. In short, the study incorporates a generic overview of the Autologous Stem Cell and Non-Stem Cell Based Therapies market based on its current status and market size, in terms of volume and returns. The study also comprises a summary of important data considering the geographical terrain of the industry as well as the industry players that seem to have achieved a powerful status across the Autologous Stem Cell and Non-Stem Cell Based Therapies market.

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Autologous Stem Cell and Non-Stem Cell Based Therapies Market Segmentation

By Type Autologous Stem Cell, Non-Stem Cell,

By Application Medical Centers and Universities, Clinical Laboratories,

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region.

Global Autologous Stem Cell and Non-Stem Cell Based Therapies Market: Competitive Landscape This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2020.

The major players in the market ANTRIA (CRO) (U.S.), BIOHEART (U.S.), BRAINSTORM CELL THERAPEUTICS (U.S.), CYTORI (U.S.), DENDREON CORPORATION (U.S.), FIBROCELL (U.S.), GENESIS BIOPHARMA (U.S.), GEORGIA HEALTH SCIENCES UNIVERSITY (U.S.), NEOSTEM (U.S.), OPEXA THERAPEUTICS (U.S.), ORGENESIS (U.S.), REGENEXX (U.S.), REGENEUS (AUSTRALIA), TENGION (U.S.), TIGENIX (BELGIUM), VIRXSYS (U.S.)

Global Autologous Stem Cell and Non-Stem Cell Based Therapies MarketThis research report providesCOVID-19 Outbreakstudy accumulated to offer Latest insights about acute features of the Autologous Stem Cell and Non-Stem Cell Based Therapies Market. The report contains different market predictions related to marketsize, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market. It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary andSWOT analysis.It presents the360-degreeoverview of the competitive landscape of the industries. Autologous Stem Cell and Non-Stem Cell Based Therapies Market is showing steadygrowthandCAGRis expected to improve during the forecast period.

The main sources are industry experts from the global Autologous Stem Cell and Non-Stem Cell Based Therapies industry, including management organizations, processing organizations, and analytical services providers that address the value chain of industry organizations. We interviewed all major sources to collect and certify qualitative and quantitative information and to determine future prospects. The qualities of this study in the industry experts industry, such as CEO, vice president, marketing director, technology and innovation director, founder and key executives of key core companies and institutions in major biomass waste containers around the world in the extensive primary research conducted for this study We interviewed to acquire and verify both sides and quantitative aspects.

Global Autologous Stem Cell and Non-Stem Cell Based Therapies Market: Regional Analysis The report offers in-depth assessment of the growth and other aspects of the Autologous Stem Cell and Non-Stem Cell Based Therapies market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

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Complete Analysis of the Autologous Stem Cell and Non-Stem Cell Based Therapies Market:

Comprehensive assessable analysis of the industry is provided for the period of 2020-2025 to help investors to capitalize on the essential market opportunities.

The key findings and recommendations highlight vital progressive industry trends in the global Autologous Stem Cell and Non-Stem Cell Based Therapies market, thereby allowing players to improve effective long term policies

A complete analysis of the factors that drive market evolution is provided in the report.

To analyze opportunities in the market for stakeholders by categorizing the high-growth segments of the market

The numerous opportunities in the Autologous Stem Cell and Non-Stem Cell Based Therapies market are also given.

Report Answers Following Questions:

What are the factors driving the growth of the market?

What factors are inhibiting market growth?

What are the future opportunities in the market?

Which are the most dynamic companies and what are their recent developments within the Autologous Stem Cell and Non-Stem Cell Based Therapies Market?

What key developments can be expected in the coming years?

What are the key trends observed in the market?

TABLE OF CONTENT

1 Report Overview

2 Global Growth Trends

3 Market Share by Key Players

4 Breakdown Data by Type and Application

5 United States

6 Europe

7 China

8 Japan

9 Southeast Asia

10 India

11 Central & South America

12 International Players Profiles

13 Market Forecast 2020-2025

14 Analysts Viewpoints/Conclusions

15 Appendix

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Autologous Stem Cell and Non-Stem Cell Based Therapies MARKET 2020 |INDUSTRY ANALYSIS, SIZE, SHARE, TRENDS, MARKET DEMAND, GROWTH, OPPORTUNITIES AND...

Finding The Achilles Heel of A Killer Parasite – Newswise

By Stem Cell Medical Center

Newswise DALLAS Sept. 24, 2020 Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published online today in Science, could change the course of this disease that kills up to 250,000 people a year.

About 240 million people around the world have schistosomiasis mostly children in Africa, Asia, and South America in populations that represent the poorest of the poor, says study leader James J. Collins III, Ph.D., associate professor in UTSWs department of pharmacology.

Most of those infected survive, but those who die often suffer organ failure or parasite-induced cancer. Symptoms can be serious enough to keep people from living productive lives, Collins says.

The parasite that causes this disease has a complicated life cycle that involves stages in both freshwater snails and mammals. Dwelling in mammalian hosts circulatory systems, schistosomes feed on blood and lay copious numbers of eggs, all while causing an array of symptoms including abdominal pain, diarrhea, bloody stool, or blood in the urine. Larval worms are released from snails into water, where the flatworms then may infect humans by penetrating the skin. Schistosomiasis may become a chronic disease that affects the person for years.

Only one drug, praziquantel, is available to treat this condition. However, Collins explains, it is of limited use it doesnt kill all intramammalian stages of the schistosome life cycle, and it has a variable cure rate in some endemic settings. Theres been little interest by pharmaceutical companies in developing new drugs for this disease, he adds, because there is no monetary incentive to do so. Consequently, relatively few studies have been devoted to understanding schistosomes basic biology, which might reveal inherent weaknesses that could serve as targets for new drugs.

To that end, Collins and his colleagues embarked upon two separate studies one at the cellular level and another at the molecular level to better understand these organisms.

In the first study, the researchers delved into the cell types that make up these flatworms. Although the worms are multicellular organisms composed of a variety of unique tissue types, researchers knew little about the different cell populations in these parasites.

With a goal to create an atlas of cell types in Schistosoma mansoni one of the schistosome species that commonly causes schistosomiasis Collins and his team used a technique called single-cell RNA sequencing that distinguishes individual cell types based on their unique gene expression patterns. With this method, they identified 68 molecularly unique clusters of cells, including a population of stem cells that form the gut. When the researchers used a targeted approach called RNA interference (RNAi) to shut down the activation of a key gene in these cells, the resulting worms couldnt digest red blood cells a key to their growth and a pivotal part of the pathology they cause.

In the second study, the researchers used RNAi to sort out the function of about 20 percent of S. mansonis protein coding genes 2,216 in total. Previously, only a handful of genes in these organisms had been assessed.

By deactivating the genes one by one, Collins and his colleagues identified more than 250 genes crucial for survival. Using a database of pharmacological compounds, the researchers then searched for drugs that had the potential to act on proteins produced by these genes, identifying several compounds with activity on worms. The team also uncovered two protein kinases a group of proteins renowned for their ability to be targeted by drugs that are essential for muscle function. When these kinases were inhibited, the worms became paralyzed and eventually died, suggesting that drugs targeting these proteins could eventually treat people with schistosomiasis. A next step in the research will be to search for inhibitors of these proteins.

Collins notes that these strides in understanding the basic biology of schistosomes could eventually lead to new treatments to save untold lives in places where schistosomiasis is endemic.

This is a very important disease that most people have never heard of, he says. We need to invest and invigorate research on these parasites.

UTSW researchers who contributed to the first study include George Wendt, Lu Zhao, Rui Chen, and Michael L. Reese. UTSW researchers who contributed to the second study include Jipeng Wang, Carlos Paz, Irina Gradinaru, and Julie N. R. Collins.

The first study was supported by grants from the National Institutes of Health (R01 R01AI121037, R01 R01AI150715, R21 R21AI133393, and F30 1F30AI131509-01A1, the Welch Foundation (I-1948-20180324 and I-1936-20170325), the National Science Foundation (MCB1553334), the Burroughs Wellcome Fund, the Wellcome Trust (107475/Z/15/Z), and the Bill and Melinda Gates Foundation (OPP1171488).

The second study was supported by grants from the National Institutes of Health (R01AI121037), the Welch Foundation (I-1948-20180324), the Burroughs Wellcome Fund, and the Wellcome Trust (107475/Z/15/Z and 206194).

James Collins is Rita C. and William P. Clements, Jr. Scholar in Biomedical Research.

About UTSouthwestern Medical Center

UTSouthwestern, one of the premier academic medical centers in the nation, integrates pioneering biomedical research with exceptional clinical care and education. The institutions faculty has received six Nobel Prizes, and includes 23 members of the National Academy of Sciences, 16 members of the National Academy of Medicine, and 13 Howard Hughes Medical Institute Investigators. The full-time faculty of more than 2,500 is responsible for groundbreaking medical advances and is committed to translating science-driven research quickly to new clinical treatments. UTSouthwestern physicians provide care in about 80 specialties to more than 105,000 hospitalized patients, nearly 370,000 emergency room cases, and oversee approximately 3 million outpatient visits a year.

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Finding The Achilles Heel of A Killer Parasite - Newswise

SHE Initiative Shines Light on Gender Disparities in Oncology Workforce – Targeted Oncology

By Stem Cell Medical Center

The Association of Community Cancer Centers (ACCC) National Oncology Conference each year helps community oncologists approach both unique and typical challenges with innovative strategies. This year, one of the challenges addressed that has been increasingly raised throughout the year was the topic of disparities in the medical field.

To close out the ACCC 37th (Virtual) National Oncology Conference, keynote speaker Nick Smith-Stanley, MBA, addressed the topic of diversity and inclusion for women in medicine, and specifically in the field of oncology.

Smith-Stanley, associate director of finance and administration, Livestrong Cancer Institutes, Dell Medical School, associate director of administration and strategic planning, Department of Oncology, Dell Medical School, The University of Texas at Austin, explained the challenges faced by women in the oncology workplace and quantified the divide seen between the number of men and women in oncology and in positions of leadership in the medical field.

By discussing the lack of women in the field of oncology, he said, it will hopefully lead to developing strategies that address such challenges, which can then lead to real change.

He also presented how the Livestrong Cancer Institutes Dell Medical School has created a program that seeks to address this gap and give the future generation of women in medicine the tools they need to succeed.

The Growing Gender Divide Across a Medical Career Span

Oncology is known to be a male-dominated field in the healthcare space. Although the number of female students and physicians in the field has grown over the past few years, the proportion of women compared to men in medicine is still less than half. Further, the numbers get lower throughout the continuum of a medical career from medical student to physician to professor and then dean.

Smith-Stanley said that, encouragingly, for the first time in history, the number of female medical students is higher than the number of male students, but the difference is marginal. The rates decrease, however, over the course of a medical career. The number of female residents and fellows is below 50% and has not changed much in the last 10 years, and specific to oncology and hematology, the proportion of female residents and fellows is below about 45%.

Among practicing physicians, only 35% are female, and within the oncology/hematology field specifically, the rate is closer to one-third. However, this is increased from 10 years ago when the rate of female physicians was only about 28% overall and about 25% in the oncology field.

Within research in general, as of 2018, 50% of STEM (science, technology, engineering, and mathematics) positions were held by women, but specifically to science and engineering, only 28% of women hold positions in these fields.

Across all disciplines in science and oncology, we see women struggling to be considered for opportunities for promotion and leadership, Smith-Stanley said. One faculty member at Dell Medical School told us that throughout her career she has seen male colleagues with fewer accomplishments get promoted at the same time. In addition, she shared that at previous institutions, rules were not as rigid for promotion and tenure for men as they were for women, they were willing to bend the rules for men, but not for women. This shows that this is not only a personal or organizational issue, it is by far a systemic issue.

He pointed out that as a result, women hold fewer positions of leadership than men. Only 19% of department chairs were held by women in the year 2019 and only 21% of full professors are female.

This poses a greater problembecause of the lack of mentorship opportunities. If our students and junior faculty are unable to identify women in positions of leadership and mentorship to help guide their career then they are less likely to progress in their career as well, he commented.

He suggested that these rates reduce across the span of a medical career due to a lack of tools, mentorship, and support given to women in medicine.

Smith-Stanley offered some strategies to bridge the gender divide through organizational changes. Starting with culture, organizational leaders must embrace and promote an all-inclusive environment. Training on diversity and bias is one way to overcome these barriers and allow for change. Providing opportunities for professional development, including mentorship and networking, can also help to retain the women in the medical workforce.

Livestrong Cancer Institutes, he said, is one of the few cancer centers across the country that is led by a woman, S. Gail Eckhardt, MD, who is the director and associate dean of cancer programs at the company. As such, Dell Medical School is focused on addressing such healthcare disparities and leaders at the Livestrong Cancer Institutes feel that they have a responsibility to address the role that women play in cancer, research, and academics.

SHE Takes a Step Towards Overcoming Gender Disparities

The Livestrong Cancer Institute stressed the use of early education and mentorship to bridge the gender gap, which ultimately led to the development of the Summer Healthcare Experience (SHE) program in oncology. SHE is a free, immersive week-long program for introducing female-identifying high school juniors and seniors to a range of career opportunities in the cancer field. The program was launched in the summer of 2019 when 8 young women from Austin were selected with health program teachers and brought to the Dell Medical School to learn more about the various careers involved with cancer care.

The SHE program sought to empower young women to take control of their education and future careers by giving them tools to overcome challenges in the workplace. The high school students were given the opportunity to participate in research and interact with the clinical teams. Participating students also came away with a general knowledge of cancer, how it is treated, and the challenges that patients with cancer and their caregivers face. Additionally, the program promoted leadership skills and professionalism that could be used throughout their career, no matter the field.

During the week, the students worked with women in the cancer center to learn about cancer anatomy and how physicians work together for the care of patients with cancer. In the wet research lab, the students were able to see cell cultures and tumor slides and they also investigated different brain tumors in the neuro-oncology lab. The students were also able to join in on the molecular tumor boards to see the interaction between various departments for deciding on optimal care for a patient. In a survivorship session, the students were also able to meet with cancer survivors and their families and learn about their cancer journeys. Additionally, the students learned about health services research in the community and how health services researchers are investigating healthcare disparities in patients with cancer.

Throughout the week, the students were able to interact with female leaders from the cancer center, including center director Eckhardt, to hear about and learn from their experiences and the challenges they faced in their careers. They also met with a number of community organizations, from American Cancer Society to the Austin Center for Grief and Loss, to hear about how these organizations are assisting patients with cancer in the city.

Its not enough to just talk about equity and inclusion. You need to have people who are invested in the conversation and the desire to make a difference. Thats exactly what we saw in the first year of SHE, Smith-Stanley said.

The students were tasked with coming up with a comprehensive care plan for a cancer case based on all they learned during the week. These plans were then presented at the end of the week to faculty from Livestrong Cancer Institutes, Dell Medical Center, the students high school teachers, and their families.

We could not have been more thrilled with the results. They were confident, they were thoughtful, they were knowledgeable, they were compassionate. The transformation that we witnessed from Monday to Friday was remarkable, Smith-Stanley commented.

Moving forward, the Livestrong Cancer Institutes hopes to expand the SHE program to more students and extend the program to 2 weeks. The program also hopes to add in more biomedical research, entrepreneurship education, a college prep day, and even a post-program internship. Livestrong Cancer Institutes is also partnering with other organizations to spread the SHE program to 4 other cancer centers, and hopefully nationwide, although this expansion has been delayed by the coronavirus disease 2019.

Reference

Smith-Stanley N. Addressing the Disparities of Women in Oncology. Presented at: ACCC National Oncology Conference; September 14-18, 2020; Virtual.

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SHE Initiative Shines Light on Gender Disparities in Oncology Workforce - Targeted Oncology

Cell Therapy Manufacturing Market to be Worth USD 8 billion by 2030, predicts Roots Analysis – The Daily Chronicle

By Stem Cell Clinic

Roots Analysis has announced the addition of Cell Therapy Manufacturing Market (2nd Edition), 2018-2030 report to its list of offerings.

Natasha Thakur, the principal analyst, stated, The growing number of cell therapy candidates continues to create an increasing demand for facilities that offer manufacturing services for these complex pharmacological interventions. Presently, over 145 companies / organizations are actively offering manufacturing services for such products. The installed global manufacturing capacity is estimated to be over 1 billion sq ft, with the maximum capacity available in North America

The report presents opinions on several key aspects of the market. Among other elements, it includes:

The report features inputs from a number of eminent industry stakeholders. Thakur remarked, Most of the experts we spoke to confirmed that the manufacturing of cell therapies is largely being outsourced due to exorbitant costs associated with setting-up such facilities. The report features detailed transcripts of discussions held with the following experts:

The research also includes detailed profiles of the following players:

For additional details, please visithttps://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing-market-2nd-edition-2018-2030/209.hl or email [emailprotected]

Contact:

Gaurav Chaudhary

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Cell Therapy Manufacturing Market to be Worth USD 8 billion by 2030, predicts Roots Analysis - The Daily Chronicle

Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni – Science Magazine

By Somatic Stem Cells

Schistosome biology illuminated

Schistosomiasis is caused by a parasitic flatworm about which little is known. Therefore, options to combat human disease caused by schistosome infection are limited. To aid in our quest to develop treatments, two studies undertook molecular investigations of the parasite Schistosoma mansoni. By generating a single-cell atlas, Wendt et al. identified the developmental trajectory of the flatworm, including the blood-feeding gut required for its survival in the host. From these data, they found a gene required for gut development that, when knocked out through RNA interference, confers reduced pathology in infected mice. Wang et al. performed a large-scale RNA interference survey of S. mansoni and identified an essential pair of protein kinases that can be targeted by approved pharmacological intervention (see the Perspective by Anderson and Duraisingh). These molecular investigations add to our understanding of the schistosome parasite and provide biological information that may help to combat this neglected tropical disease.

Science, this issue p. 1644, p. 1649; see also p. 1562

Schistosome parasites kill 250,000 people every year. Treatment of schistosomiasis relies on the drug praziquantel. Unfortunately, a scarcity of molecular tools has hindered the discovery of new drug targets. Here, we describe a large-scale RNA interference (RNAi) screen in adult Schistosoma mansoni that examined the function of 2216 genes. We identified 261 genes with phenotypes affecting neuromuscular function, tissue integrity, stem cell maintenance, and parasite survival. Leveraging these data, we prioritized compounds with activity against the parasites and uncovered a pair of protein kinases (TAO and STK25) that cooperate to maintain muscle-specific messenger RNA transcription. Loss of either of these kinases results in paralysis and worm death in a mammalian host. These studies may help expedite therapeutic development and invigorate studies of these neglected parasites.

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Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni - Science Magazine

Human Embryonic Stem Cells Market – Growth, Trends, and Forecast (2020 – 2025) – GlobeNewswire

By Stell Cell Research

September 23, 2020 15:03 ET | Source: ReportLinker

New York, Sept. 23, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Human Embryonic Stem Cells Market - Growth, Trends, and Forecast (2020 - 2025)" - https://www.reportlinker.com/p05974111/?utm_source=GNW In the United States, two major government agencies, National Institutes of Health (NIH) and California Institute of Regenerative Medicine (CIRM), fund almost all the translational researches and regenerative medicine development in the country. It is estimated that the United States government invests around USD 800-900 million every year in stem cell research. Additionally, other factors such as the high prevalence of cardiac and malignant diseases, and rising demand for regenerative medicines are expected to drive the market.

Key Market Trends Stem Cell Biology Research Segment is Expected to Show Better Growth in the Forecast Years

Based on the application, it is segmented into regenerative medicine, stem cell biology research, tissue engineering, and toxicology testing. Stem cell biology research will show better growth, owing to the high prevalence of cardiac and malignant diseases. An article published by the ISSCR (International Society for Stem Cell Research) reported that the stem cells hold potential for the treatment of Parkinsons disease in humans. Recently, one of the market players, International Stem Cell Corporation (ISCO), received the patent covering methods for generating HLA homozygous parthenogenetic human stem cell lines from unfertilized eggs. The patent was issued in Australia. Furthermore, to boost the pace of stem cell research, the government is providing funding opportunities to researchers. Thus, owing to these factors, the market studied is expected to witness a high growth rate over the forecast period.

North America Dominates the Human Embryonic Stem Cells Market

The human embryonic stem cells market is expected to dominate in the North America region owing to extensive research activities, along with high burden of chronic diseases and genetic disorders in the region. The United States also shows a high incidence of other diseases, such as diabetes, heart disease, renal failure, and osteoporosis. Human embryonic stem cells have high potential for use in treatment and may become a standard of care for these diseases. Additionally, the FDA has approved clinical trials, which indicated the use of stem cells. Hence, these factors are expected to influence the growth of the human embryonic stem cells market over the forecast period.

Competitive Landscape The global players into the human embryonic stem cells market are Astellas Pharma Inc, PeproTech Inc, Lineage Cell Therapeutics Inc, Merck KGaA, PromoCell GmbH, STEMCELL Technologies Inc, Thermo Fisher Scientific and ViaCyte, Inc.

Reasons to Purchase this report: - The market estimate (ME) sheet in Excel format - 3 months of analyst support Read the full report: https://www.reportlinker.com/p05974111/?utm_source=GNW

About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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Human Embryonic Stem Cells Market - Growth, Trends, and Forecast (2020 - 2025) - GlobeNewswire

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