Infection Control in Cancer Therapy market maintaining a strong outlook heres why – Levee Report

The latest research report published by Ample Market Research Infection Control in Cancer Therapy Market with 150 + pages of business strategy analysis taken up by key and emerging players in the industry and provides know-how on current market growth, environment, innovations, drivers, opportunities, market perspective, and status.

Understanding the segments helps in identifying the importance of different factors that aid market growth. Some of the Major Companies covered in this Research are Kimberly Clark Corporation, 3M Healthcare Company, Honeywell International, Inc., Getinge Group AB, Sterigenics International, Sakura Global Holding Company, Arizant Healthcare Inc., Nordion, Cisa S.P.A., Steris Corporation, Nordion, Inc., Ahlstrom Filtration LLC, Membrana GmbH, Synergy Health, Plc, Advanced Sterilization Products Services, Inc etc.

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Browse in-depth TOC, market details, tables and figures on Infection Control in Cancer Therapy Market by Application (Radiation Therapy, Immunotherapy, Traditional Surgery, Stem Cell Transplant Therapy, Chemotherapy, Targeted Therapy, Photodynamic Therapy, Other, Market segment by Application, split into, Hospital, Pharmaceutical Companies, Medical device companies, Other), Product Type (Radiation Therapy, Immunotherapy, Traditional Surgery, Stem Cell Transplant Therapy, Chemotherapy, Targeted Therapy, Photodynamic Therapy, Other), Business Scope, Production, and Outlook, Estimate to 2025

At last, all parts of the Infection Control in Cancer Therapy Market are quantitatively also subjectively valued to think about the Global just as regional market equally. This market study presents basic data and true figures about the market giving a deep analysis of this market based on market trends, market drivers, constraints, and future prospects. The report supplies the worldwide monetary challenge with the help of Porters Five Forces Analysis and SWOT Analysis.

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The global impacts of the coronavirus disease 2019 (COVID-19) have significantly affected the Infrastructure in the overall market in 2020. The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor events restricted; over forty countries state of emergency declared; massive slowing of the supply chain; stock market volatility; falling business confidence, growing panic among the population, and uncertainty about future. Know more with the latest edition of Infection Control in Cancer Therapy Market Study; Early buyers will receive 20% customization free on report

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Customization of the report: The report can be tailored up to 3 companies or countries or 40 analyst hours according to your needs for added data.

The following points are highlighted on the basis of product- named segments and sub-market segments:

Infection Control in Cancer Therapy Market By Application/End-User (Value and Volume from 2019 to 2025) : Radiation Therapy, Immunotherapy, Traditional Surgery, Stem Cell Transplant Therapy, Chemotherapy, Targeted Therapy, Photodynamic Therapy, Other, Market segment by Application, split into, Hospital, Pharmaceutical Companies, Medical device companies, Other

Market By Type (Value and Volume from 2019 to 2025) : Radiation Therapy, Immunotherapy, Traditional Surgery, Stem Cell Transplant Therapy, Chemotherapy, Targeted Therapy, Photodynamic Therapy, Other

Infection Control in Cancer Therapy Market by Key Players: Kimberly Clark Corporation, 3M Healthcare Company, Honeywell International, Inc., Getinge Group AB, Sterigenics International, Sakura Global Holding Company, Arizant Healthcare Inc., Nordion, Cisa S.P.A., Steris Corporation, Nordion, Inc., Ahlstrom Filtration LLC, Membrana GmbH, Synergy Health, Plc, Advanced Sterilization Products Services, Inc

Geographically, this report is segmented into some key Regions, with the manufacture, depletion, revenue (million USD), and market share and growth rate of Infection Control in Cancer Therapy in these regions, from 2012 to 2022 (forecast), covering China, USA, Europe, Japan, Korea, India, Southeast Asia & South America and its Share (%) and CAGR for the forecasted period 2019 to 2025.

Key Development in the Market: This segment of the Infection Control in Cancer Therapy report fuses the major developments of the market that contains confirmations, composed endeavors, R&D, new thing dispatch, joint endeavors, and the relationship of driving members working in the market.

Informational Takeaways from the Market Study: The report Infection Control in Cancer Therapy matches the completely examined and evaluated data of the noticeable companies and their situation in the market considering the impact of Coronavirus. The measuring tools including SWOT analysis, Porters five powers analysis, and assumption return debt were utilized while separating the improvement of the key players performing in the market.

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Some important topic for stakeholders and business professionals to broaden their role in the Infection Control in Cancer Therapy Market :

Q 1. Which Region offers the most rewarding open doors for the market Ahead of 2020?

Q 2. What are probably the most encouraging, high-development scenarios for Infection Control in Cancer Therapy movement showcase by applications, types and regions?

Q 3. What segments grab most noteworthy attention in Infection Control in Cancer Therapy Market in 2019 and beyond?

Q 4. Who are the significant players confronting and developing in Infection Control in Cancer Therapy Market?

Q 5. What are the business threats and Impact of the COVID scenario Over the market Growth and Estimation?

For more information please read Content Table @: https://www.amplemarketreports.com/report/covid-19-outbreak-impact-on-global-infection-control-in-cancer-therapy-market-1862637.html

TOCs Main Pole:

Chapter 1 Infection Control in Cancer Therapy Market Business Overview

Chapter 2 Major Breakdown by Type [Radiation Therapy, Immunotherapy, Traditional Surgery, Stem Cell Transplant Therapy, Chemotherapy, Targeted Therapy, Photodynamic Therapy, Other]

Chapter 3 Major Application Wise Breakdown (Revenue & Volume)

Chapter 4 Manufacture Market Breakdown

Chapter 5 Sales & Estimates Market Study

Chapter 6 Key Manufacturers Production and Sales Market Comparison Breakdown

Chapter 8 Manufacturers, Deals and Closings Market Evaluation & Aggressiveness

Chapter 9 Key Companies Breakdown by Overall Market Size & Revenue by Type

Chapter 11 Business / Industry Chain (Value & Supply Chain Analysis)

Chapter 12 Conclusions & Appendix

Thank you for reading this article; you can also get a wise section or area report versions of individual chapters such as North America, Europe, or Asia.

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Infection Control in Cancer Therapy market maintaining a strong outlook heres why - Levee Report

Dad with incurable cancer takes on 300 mile cycle challenge ahead of stem cell transplant – HeraldScotland

A FATHER-of-two with a rare and incurable cancer is to take on a cycle challenge ahead of a potentially life-changing stem cell transplant.

Andrew Slorance, 49, was first diagnosed with mantle cell lymphoma, a member of the non-Hodgkins lymphoma family in 2015 and had since gone on to have one transplant.

However, while he has been on a cocktail of drugs to help suppress the cancer, which is incurable, he needs to undergo a second transplant this time with a stem cell donor transplant.

His operation is now scheduled to go ahead later this year following a slight delay with the impact of coronavirus, but before then he will be saddling up for a 300-mile bike challenge in aid of Cancer Research UK next month.

I didnt think I would see my 50th birthday at one point following my diagnosis, but with developments in medicine and science I have benefited, said Mr Slorance. The cycle challenge is a way of giving back and helping to raise money for much-needed research which could save lives. It is also a chance for me to get out on the bike and keep me fit for my next operation.

Mr Slorance thought he was just recovering from a gastric flu in summer 2015, but after still feeling tired and sluggish he decided to get checked out.

Following tests I was told I had a rare and incurable cancer called mantle cell lymphoma. By December, I was undertaking a gruelling four-month programme of chemotherapy before a life-prolonging stem cell transplant in spring 2016. At the time of diagnosis, the average life expectancy for MCL wasnt great, but science and luck have been on my side.

Last year, Mr Slorance relapsed but has benefited from a new drug that is controlling his current cancer ahead of his big operation in January next year.

He added: It wont last forever, though, and I need to face another stem cell transplant, this time the much more riskier donor or allogeneic transplant. If it goes well it could prove curative. But if it fails, well then that is another story. The drugs wont control the cancer forever so it is about getting to the point to make sure you can get the benefit of the drugs before going for the transplant.

With this one being a donor transplant there could be more chance of rejection like with any organ transplant, but the long-term benefits could be much greater. They cant say absolutely at the stage that the transplant is curative.

While waiting for his transplant date, Mr Slorance had found focusing on the cycle challenge and it has been all the more enjoyable being able to get out as shielding restrictions eased. He has been working from home in his role for the Scottish Government and had to take precautions in the family home.

Mr Slorance added: With four of us in the house we had to look at ways of socially distancing.

I was sleeping and working in a bedroom and judged my meal times separately from the family. It was great to get out in the garden, but even then I would have my own little area while the others would have theirs.

It has certainly been hard in these times when no-one has been able to hug one another.

Mr Slorance has been building up his mileage daily and is attempting to cover the 300 miles this month in case he cant manage in the official month of September.

After three months of shielding I finally got out for exercise on June 18. Ive bought myself an electric bike. Not as a cheat but because it helps to neutralise the many hills around my Edinburgh home.

The pills I am taking have a side-effect that can cause joint pain. I have also been sleeping on a bed settee since March. Those things combined have left me with excruciatingly painful and uncomfortable knees and shoulders.

Without the extra help of an electric bike theres no way Id be able to manage the effort needed to tackle the climbs, but I do put a lot of effort in on the flat.

Already he has been building up from seven miles a day while returning to his commute and has already raised more than 3,000.

Mr Slorance said: I hope I can raise as much money as I can for Cancer Research UK. Charities have been affected by lockdown and raising money has not been easy. In the past I have raised money for Maggies Centres, but this seemed a good way to help.

I already owe my extended life to cancer research and new treatments, but the median survival rate for MCL has only increased to six to seven years, so I could really benefit from more scientific advances.

To donate go to fundraise.cancerresearchuk.org/page/andrews-cycle-300-fundraising-page-202

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Dad with incurable cancer takes on 300 mile cycle challenge ahead of stem cell transplant - HeraldScotland

Impact Analysis of COVID-19 on Pluripotent Stem Cell Market Outlook 2018-2025 by Emerging Trends, Technology, Leading Companies, And Future Forecast -…

Kenneth Research has recently published a report on the Global and Southeast Asia Pluripotent Stem Cell Industry which is anticipated to grow by a CAGR of X% during the forecast period 2013-2025.

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Impact Analysis of COVID-19 on Pluripotent Stem Cell Market Outlook 2018-2025 by Emerging Trends, Technology, Leading Companies, And Future Forecast -...

Chromosomal Rearrangements Associated with Chemotherapeutic Drug Resistance | McDonnell Boehnen Hulbert & Berghoff LLP – JD Supra

Chemotherapeutic drug resistance is one reason cancer remains an unsolved clinical problem despite the efforts ever since President Nixon declared his "War on Cancer" in 1971. Cancer cells, due in part to the genetic destabilization characteristic of the disease, are capable of expressing genes (normal or aberrant) that permit the cell to avoid the cytotoxic effect of such drugs with the patient providing the situs of selection for and growth of resistant cells. The phenomenon is certain tumor types can have more deleterious consequences than in others, and this is particularly true for glioblastomas (and their non-malignant counterparts, gliomas), cancer of the cells that protect neurons in brain. That organ, confined to the skull, cannot accommodate tumor growth without damaging the brain with which it is confined.

The chemotherapeutic drug of choice for treating glioblastomas is temezolomide (TMZ), an oral alkylating agent that had its chemotherapeutic effect by introducing alkyl groups onto nucleotide bases (preferably at the N-7 and O-6 positions of guanine and N-3 position of adenine) in tumor cell DNA preferentially (due to the greater amount of DNA synthesis occurring in these cells) and disrupting the process leading to cell death (the O-6 methylation having the greatest capacity to induce apoptosis or programmed cell death).O-6-methylguanosnine DNA methyltransferase (MGMT) is the cellular enzyme responsible for repairing alkylated bases in DNA and reduced expression of this gene (e.g., by hypermethylation of the MGMT promoter) is a biomarker for TMZ sensitivity in gliomas and glioblastomas. Recently, a multinational team of researchers* reported genetic rearrangements associated with TMZ resistance, in a paper entitled "MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas" published in Nature Communications. This paper shows a subset of gliomas with rearrangements in the MGMT gene that produce overexpression of the gene and resistance as a result. These authors screened 252 TMZ-treated recurrent gliomas by RNA sequencing and found eight different MGMT genetic fusions (designated BTRC-MGMT,CAPZB-MGMT,GLRX3-MGMT,NFYC-MGMT,RPH3A-MGMT, andSAR1A-MGMTin high-grade gliomas, HGG, andCTBP2-MGMTandFAM175B-MGMT in low-grade gliomas, LGG, in the paper) in seven patients (6 females) with recurrent disease, created by chromosomal rearrangement (see Figure 1c from paper; shown below). These individuals' tumors showed "significantly higher" expression of the rearranged MGMT gene product.

Upon further study, the authors report that five of the eight rearranged genes were located on Chromosome 10 in the vicinity of the MGMT gene itself. The breakpoint in the MGMT was uniformly found at the boundary of exon 2 of the MGMT gene, at a point 12 basepairs upstream of the ATG translation "start" codon. In three of the rearrangements, the breakpoint in the partner gene in the genetic fusion was found in the 5' untranslated region (UTR). All fusions were found to be in-frame (i.e., the reading frame of the MGMT transcript was not disrupted) and the functional regions of the MGMT protein (the methyltransferase domain and DNA-binding domain) were intact. A more fine-structure mapping experiment in the genetic rearrangement resulting in FAM175B-MGMTfound that the fusion was the consequence of a deletion of 4.8 Mb.

The effect of these rearrangements on MGMT expression was elucidated using CRIPSR-Cas9 to produce the BTRC-MGMT, NFYC-MGMT, SAR1A-MGMT, and CTBP2-MGMT rearrangements in cells of two glioblastoma cell lines, U251 and U87. When these cells and their untreated counterparts were challenged by growth in vitro with TMZ, only cells bearing the rearrangements (as confirmed by PCR analysis) were shown to be TMZ resistant. Unlike genetic rearrangements in other cancers that produce fusion proteins (such as the abl-bcr gene produced in chronic myelogenous leukemia bearing the diagnostic Philadelphia chromosome), because most of the rearrangements found involving the MGMT gene were located upstream of the initiation codon of the MGMT gene these authors reasoned that these rearrangements produce increased expression of MGMT leading to TMZ resistance because the cells were better able to repair the methylation injury and replicate functionally. This hypothesis was supported by real-time quantitative PCR analysis of MGMT transcripts in cells bearing the rearrangements, that showed a "striking" increase in expression of MGMT-encoding transcripts (an observation also found in tumors from patients whose gliomas or glioblastomas showed these rearrangements), and Western blot analysis confirmed higher expression levels of the MGMT protein. In two of the rearrangements (BTRC-MGMT and NFYC-MGMT), higher molecular weight fusion proteins were detected as predicted from the genetic data. These results were also replicated in patient tumor-derived stem cells for the BTRC-MGMTandSAR1A-MGMT rearrangements.

These results, and the researchers' conclusion that these rearrangements caused TMZ resistance by overexpression of MGMT, were confirmed by re-establishing TMZ sensitivity in these cells in the presence of O6-benzylguanine (O6-BG), an MGMT inhibitor. These results were further confirmed by detection of double-strand breaks in DNA in these cells in the presence of TMZ and O6-BG.

The relevance of these results to TMZ resistance in vivo was demonstrated using nude mouse xenograft models bearing tumors produced using BTRC-MGMT U251 cells and U251 cells without the rearrangement as control; these cells also contained a recombinant luciferase gene. Mice containing the rearrangement showed no significant prolongation of lifespan in the presence or absence of TMZ, indicating tumor cell resistance, whereas TMZ treatment of nave U251 cells showed improved survival.

While hypomethylation of the native MGMT promoter is the most frequently change associated with TMZ resistance, the results presented in this paper illustrate an alternative mechanism for glioblastomas and gliomas to acquire resistance to TMZ, the only current chemotherapeutic drugs for these maladies. Because these rearrangements were found in patients with recurrent tumors, these authors hypothesize that the rearrangements were selected or by TMZ treatment. A similar rearrangement has also been found in another cancer, medulloblastoma, after TMZ relapse. These authors also suggest that detection of these rearrangements can be used clinically to determine appropriate treatment modalities, particularly for recurrent disease.

* Seve Ballesteros Foundation Brain Tumor Group, Molecular Oncology Programme, Spanish National Cancer Research Center; Division of Life Science, Department of Chemical and Biological Engineering, Center of Systems Biology and Human Health and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology; Beijing Neurosurgical Institute, Capital Medical University; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine; Department of Systems Biology, Columbia University; The Jackson Laboratory for Genomic Medicine; and Molecular Cytogenetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Center, CNIO, 28029, Madrid, Spain

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Chromosomal Rearrangements Associated with Chemotherapeutic Drug Resistance | McDonnell Boehnen Hulbert & Berghoff LLP - JD Supra

Boy, 4, may look fighting fit but only has months to live – unless you can save him – Mirror Online

His name means brave in Hindi. And for four year-old Veer Gudhka that couldnt be more appropriate.

For while the bubbly little boy might look fighting fit, he actually has just months to live.

Veer suffers from a rare blood disorder called Fanconi anaemia, which results in a decreased production of all types of blood cells.

But a stem cell donor will save his life.

In a heartfelt video message, the plucky toddler asks Sunday Mirror readers: Please be my life-saver? Will you be my superhero?

And today his family are appealing to those from BAME communities to help by signing up to the Anthony Nolan stem cell register.

Mum Kirpa and dad Nirav know the odds are stacked against them getting that all-important call because they are of Indian descent.

While 69 per cent of Northern European patients find the best possible stem cell match from a stranger, this drops to just 20 per cent for those with black, Asian or ethnic minority backgrounds.

Survival

Currently only two per cent of the population is on the UK stem cell register. And with Asians making up just six per cent of the UK population, there is a smaller pool of potential donors.

Veer was diagnosed with the blood disorder last August, after he started suffering from extreme fatigue, and was referred for tests.

Doctors said he would need a stem cell transplant within three years for a chance of survival.

They hoped to buy Veer some time by putting him on steroids to boost his blood counts. But his condition has deteriorated fast.

Recent tests at Great Ormond Street Hospital in London show he now has just three to four months to find a donor.

Kirpa and Nirav were both tested, along with Veers six-year-old sister Suhani, but none of them were a match.

A search on the global stem cell register also drew a blank.

And his dad has been trying to encourage his fellow countrymen and women in India to join the register.

They have even signed up a female battalion of the Indian Army.

Kirpa, 37, from Harrow, London, said: We just feel so scared were going to lose our cheeky, amazing little boy. To look at Veer you wouldnt know hes critically ill.

Like his name, hes been brave from the start. Hes undergone countless tests and hospital visits but has had a constant smile on his face.

"He knows he needs a superhero to step forward, but his optimism and enthusiasm are infectious and keep us all going.

She added: Going on the register is incredibly quick and donating cells if you match someone in need is painless.

You can join the Anthony Nolan stem cell register today.

Nine out of 10 people donate their stem cells through the bloodstream in a simple IV process called peripheral blood stem cell collection.

One in 10 will have their stem cells collected via the bone marrow itself, while under general anaesthetic. Doctors transplant the new, healthy cells via the patients bloodstream, where they begin to grow and create healthy red blood cells, white blood cells and platelets.

A perfect match from a donor can mean a lifelong cure.

Veers dad Nirav, 40, said: I only learned about the Anthony Nolan stem cell register two years ago and even then I assumed it would involve long and painful procedures.

We need to raise awareness to save lives in every community.

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Boy, 4, may look fighting fit but only has months to live - unless you can save him - Mirror Online

Post chemotherapy may leave patients vulnerable to infections – APN News

Published on August 7, 2020

Mr. Raktim Chattopadhyay, Founder & CEO, Esperer Onco Nutrition (EON)

The link between the immune system and cancer has been widely appreciated for over a century and was first highlighted by Rudolph Virchow over 150 years ago . The underlying basis for this relationship between cancer and immunity involves three basic principles of how the immune system acts to defend and protect an individual: it detects nonself antigens from pathogens or infected/malignant cells; it encompasses effector functions to specifically target and destroy the pathogen or infected/malignant cells while protecting the host, and it develops immunological memory via the adaptive immune responses for subsequent defence mechanisms following an injury or an attack against the host . Through this process, the immune system has acquired characteristics that give rise to the paradigm known as immunoediting, which provides a balance between immune surveillance and cancer progression in the realm of oncology.In the rapidly evolving field of immune-oncology, understanding the tumor-specific immune response enhances understanding of cancer resistance.

Most cancer patients know that chemotherapy weakens their immune systems, putting them at risk for viral and bacterial infections. A month or two after chemo ends, most people think their immune system has returned to normal. Research suggests that the effects of chemotherapy can compromise part of the immune system for up to nine months after treatment, leaving patients vulnerable to infections especially with certain type of chemotherapy treatment regimen.

So, cancer and cancer treatments can affect the immune system and other body systems in different ways. People with cancer might be more likely to get infections because of:

Cancer treatments can interfere with the way the immune system works. The damage can be short- or long-term. For example, if a person with cancer has their spleen removed due to cancer, this causes long-term damage because the spleen is part of the immune system. On the other hand, radiation therapy, immunotherapy, and chemotherapy, either alone or in combination can lead to short-term (temporary) immune system damage because they affect immune system blood cells for a fairly short period of time. Abone marrow or stem cell transplant uses very high-dose treatments to kill cancer cells that also damageimmune system cells for weeks to months.

Keeping the above in mind cancer patients must consider the following as per international guidelines:

Dont ignore minor symptoms. If you are feeling unwell, get to your doctor and get it checked out right away. What may be a minor issue could turn into something bigger.

Talk to your health care provider to make sure youre up to date on all of your vaccines. Many cancer patients after treatment should be able to receive many vaccines, including flu and pneumonia vaccines.

Exercise and eat healthfully. Those things never hurt immune response or your recovery.

If you smoke, try to quit.

If someone in your family or in your care has cancer, make sure youre up to date on vaccines and preventive care. The last thing you want to do is develop an infection that doesnt allow you to care for them or puts them at risk.

Since patients are most at risk right after theyve received chemo. Its really important to protect your family members when theyre at the highest risk for major infectious complications.

Supporting the immune system while battling cancer is imperative and one of the factors that aid in the healing process from the aftermath of the treatment therapy. Protective effects can be observed while balancing dietary and lifestyle needs, however, these alone do not promise an immunity boost. The immune system works as powerful weapon against disease, but it is a known fact that with cancer, immunity is at high risk where healthy cells are attacked causing a variety of side effects.

Cancer patients are at a natural high risk of malnutrition as chemotherapies, radiations and surgeries can lead to loss of appetite, stress, fatigue, anxiety making it difficult to eat with a high appetite loss. This leads to a significant reduced response in cancer treatment, increases risk of survival. Cancer cells replicate by division to replace old cells and multiply thus some damaged cells might migrate to other tissues causing tumour growth. The longer, cancer continues to grow the lesser possibilities are available for the immune system to recognize damaged cells and destroy them.

Vitamins, foods, minerals are recommended by doctors but a key concern to examine is are these long term & sustainable to ensure quality life for patients?

A need for preparing the body for heavy dose of cancer treatment at the time of diagnosis, during treatment and post procedure is important for long term risk benefits. All 3 phases are different and require nutritional care basis the cell biology of the body. Health supplements of the correct formulation with technology backed research can be an optimum solution. The supplements can bring about efficacy in the main therapy of cancer disease management and improve overall quality of life.

Time has come to focus on optimal physical and psycho-social well-being of the patient in cancer therapy. The treatment of a lethal and supposedly incurable disease like cancer takes a toll on people emotionally, financially and physically. The right approach for organizations to help mitigate the risks of cancer though various methods would be to have an all-inclusive outlook catering to all of the above effects. The goal should be to help and support the end user with a view of futuristic need for living a fulfilling life even after being cured, while focusing on every aspect of oncology. A certain kind of after care is always mandatory during & post treatment which could be complex and costly. Anticancer products is the future, which will have to align parallel in such a way so the therapy protocol can be made affordable to the receivers.

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Post chemotherapy may leave patients vulnerable to infections - APN News

Immatics Extends Cell Therapy Manufacturing Collaboration with UTHealth | 2020-08-06 | Press Releases – Stockhouse

Houston, Texas, Aug. 06, 2020 (GLOBE NEWSWIRE) --

Houston, Texas, August 6, 2020 Immatics N.V. (NASDAQ: IMTX; Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell redirecting cancer immunotherapies, today announced the extension of its cell therapy manufacturing collaboration with The University of Texas Health Science Center at Houston (UTHealth), in Houston, Texas. The continued collaboration grants Immatics access to UTHealth’s state-of-the-art cGMP manufacturing infrastructure at the Evelyn H. Griffin Stem Cell Therapeutics Research Laboratory, enabling continued production and supply of Immatics’ specialized, cell-based product candidates for testing in multiple clinical trials. Maximum capacity of the facility is anticipated at 48 ACTengine® T cell products per month. The new agreement will run until the end of 2024. Under the agreement, UTHealth will provide Immatics with exclusive access to three cGMP suites and support areas for the manufacturing of various Adoptive Cell Therapy (ACT) products. Therapeutic T cell production will be carried out by Immatics’ manufacturing personnel and will be supported by a UTHealth-Immatics joint quality team.

Steffen Walter, Ph.D., Chief Technology Officer at Immatics, commented: During the last five years, we have established a strong and productive partnership with UTHealth that has enabled the initiation of four ongoing clinical trials. As we remain focused on the development of our clinical pipeline, this extension of our collaboration with UTHealth will fulfill Immatics’ manufacturing needs for our early-stage ACT clinical programs for the next four years. Being able to rely on a partner with profound cell therapy expertise who is familiar with our technologies and can support cGMP cell therapy production is critical to ensuring the advancement of our clinical trials. We look forward to continuing this fruitful collaboration with the experts at UTHealth.”

Fabio Triolo, D.d.R., M.Phil., Ph.D., The Clare A. Glassell Distinguished Chair and Director of the Cellular Therapy Core at UTHealth, added: Signing the extended contract with Immatics fits into our strategy at UTHealth of supporting the development of new treatments for patients in need. We therefore look forward to continuing our collaboration and further leveraging the potential of our manufacturing capabilities.”

About Immatics’ ACT Programs ACTengine® is a personalized approach in which the patient’s own T cells are genetically modified to express a novel proprietary TCR cognate to one of Immatics’ proprietary cancer targets which are then reinfused back into the patient. Immatics’ latest proprietary ACTengine® manufacturing processes are designed to generate cell product candidates within a short six day manufacturing window and to deliver highly proliferative T cells, with the capability to infiltrate the patient’s tumor and function in a challenging solid tumor microenvironment. The process is designed to rapidly produce younger, better-persisting T cells capable of serial” killing tumor cells in vitro. Immatics’ is further advancing the ACT concept beyond individualized manufacturing with its product class ACTallo® which is being developed to generate off-the-shelf” cellular therapies.

More information on the clinical trials can be found at the following links: https://immatics.com/clinical-programs/ and https://clinicaltrials.gov/.

- ENDS - Notes to Editors

About Immatics Immatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets. This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer.

For regular updates about Immatics, visit http://www.immatics.com. You can also follow us on Twitter and LinkedIn.

About UTHealth Established in 1972 by The University of Texas System Board of Regents, The University of Texas Health Science Center at Houston (UTHealth) is Houston’s Health University and Texas’ resource for health care education, innovation, scientific discovery and excellence in patient care. The most comprehensive academic health center in the UT System and the U.S. Gulf Coast region, UTHealth is home to Jane and Robert Cizik School of Nursing, John P. and Kathrine G. McGovern Medical School and schools of biomedical informatics, biomedical sciences, dentistry and public health. UTHealth includes The University of Texas Harris County Psychiatric Center, as well as the growing clinical practices UT Physicians, UT Dentists and UT Health Services. The university’s primary teaching hospitals are Memorial Hermann-Texas Medical Center, Children’s Memorial Hermann Hospital and Harris Health Lyndon B. Johnson Hospital. For more information, visit http://www.uth.edu.

About the Evelyn H. Griffin Stem Cell Therapeutics Research Laboratory The Evelyn H. Griffin Stem Cell Therapeutics Research Laboratory, which is part of the Cellular Therapy Core at UTHealth, has been Immatics’ manufacturing partner since 2015. The site is a U.S. Food and Drug Administration (FDA)-registered and inspected cGMP facility that has received accreditation from the Foundation for Accreditation of Cellular Therapy (FACT) as well as certification from the Clinical Laboratory Improvement Amendment (CLIA) and the College of American Pathologists (CAP).

Forward-Looking Statements Certain statements in this press release may be considered forward-looking statements. Forward-looking statements generally relate to future events or Immatics’ future financial or operating performance. For example, statements concerning the timing of product candidates and Immatics’ focus on partnerships to advance its strategy are forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as may”, should”, expect”, intend”, will”, estimate”, anticipate”, believe”, predict”, potential” or continue”, or the negatives of these terms or variations of them or similar terminology. Such forward-looking statements are subject to risks, uncertainties, and other factors which could cause actual results to differ materially from those expressed or implied by such forward looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by Immatics and its management, are inherently uncertain. New risks and uncertainties may emerge from time to time, and it is not possible to predict all risks and uncertainties. Factors that may cause actual results to differ materially from current expectations include, but are not limited to, various factors beyond management's control including general economic conditions and other risks, uncertainties and factors set forth in filings with the Securities and Exchange Commission (SEC). Nothing in this presentation should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Immatics undertakes no duty to update these forward-looking statements.

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Immatics Extends Cell Therapy Manufacturing Collaboration with UTHealth | 2020-08-06 | Press Releases - Stockhouse

Potential Impact of COVID-19 Pandemic on Global Stem Cell Assay Coronavirus Impact Editon of Key Companies Merck, Thermo Fisher Scientific, GE…

Report is a detailed study of the Stem Cell Assay market, which covers all the essential information required by a new market entrant as well as the existing players to gain a deeper understanding of the market.The primary objective of this research report named Stem Cell Assay market is to help making reliable strategic decisions regarding the opportunities in Stem Cell Assay market. It offers business accounts, industry investors, and industry segments with consequential insights enhancing decision making ability.nicolas.shaw@cognitivemarketresearch.com or call us on +1-312-376-8303.

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Global and Regional Stem Cell Assay Market Segmentation by Type: Viability, Purification, Identification

Global Stem Cell Assay Market Segmentation by Applications: Regenerative Medicine, Clinical Research

Major Market Players with an in-depth analysis: Merck, Thermo Fisher Scientific, GE Healthcare, Agilent Technologies, Bio Rad Laboratories, Promega, Cell Biolabs, PerkinElmer, Miltenyi Biotec, HemoGenix, Bio Techne, STEMCELL

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Regional Analysis for Stem Cell Assay North America (United States, Canada) Europe (Germany, Spain, France, UK, Russia, and Italy) Asia-Pacific (China, Japan, India, Australia, and South Korea) Latin America (Brazil, Mexico, etc.) The Middle East and Africa (GCC and South Africa)

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Potential Impact of COVID-19 Pandemic on Global Stem Cell Assay Coronavirus Impact Editon of Key Companies Merck, Thermo Fisher Scientific, GE...

Canine Stem Cell Therapy Market Analysis Of Growth, Trends Progress And Challenges Till Upcoming Year – Connected Lifestyle

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Canine Stem Cell Therapy Market Analysis Of Growth, Trends Progress And Challenges Till Upcoming Year - Connected Lifestyle

Global Stem Cell Therapy for Osteoarthritis Market Research Study 2020 Insights with COVID-19 Impact Analysis by 2020Mesoblast, Regeneus, U.S. Stem…

Rising number of corona virus cases has impacted numerous lives and led to numerous fatalities, and has affected the overall economic structure globally. The Stem Cell Therapy for Osteoarthritis has analyzed and published the latest report on the global Stem Cell Therapy for Osteoarthritis market. Change in the market has affected the global platform. Along with the Stem Cell Therapy for Osteoarthritis market, numerous other markets are also facing similar situations. This has led to the downfall of numerous businesses, because of the widespread increase of the number of cases across the globe.href=mailto:nicolas.shaw@cognitivemarketresearch.com>nicolas.shaw@cognitivemarketresearch.com or call us on +1-312-376-8303.

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The major players in the Stem Cell Therapy for Osteoarthritis market are Mesoblast, Regeneus, U.S. Stem Cell, Anterogen, Asterias Biotherapeutics . Some of the players have adopted new strategies to sustain their position in the Stem Cell Therapy for Osteoarthritis market. A detailed research study is done on the each of the segments, and is provided in Stem Cell Therapy for Osteoarthritis market report. Based on the performance of the Stem Cell Therapy for Osteoarthritis market in various regions, a detailed study of the Stem Cell Therapy for Osteoarthritis market is also analyzed and covered in the study.

Report Scope: Some of the key types analyzed in this report are as follows: Monotherapy, Combination Therapy

Some of the key applications as follow: Osteoarthritis (unspecified), Knee Osteoarthritis, Shoulder Osteoarthritis, Hip Osteoarthritis

Following are the major key players: Mesoblast, Regeneus, U.S. Stem Cell, Anterogen, Asterias Biotherapeutics

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The report also provides detailed information on the research methodologies, which are used for the analysis of the Stem Cell Therapy for Osteoarthritis market. The methods are covered in detail in this section of the report. For the analysis of the market, several tools are used for the extraction of the market numbers. Among the several tools, primary and secondary research studies were also incorporated for the research study. These were further analyzed and validated by the market experts, to increase precision and make the data more reliable.

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Global Stem Cell Therapy for Osteoarthritis Market Research Study 2020 Insights with COVID-19 Impact Analysis by 2020Mesoblast, Regeneus, U.S. Stem...