DKMS-BMST Foundation India completes one year of operation in India – Express Healthcare

Celebrates milestone with registration of over 42,000 potential life savers in same time period in country

This World Blood Cancer Day, DKMS-BMST celebrates a milestone of registering over 42,000 potential lifesavers in a time period of one year in India. This group comprises of individuals who range from 18-50 years of age and have pledged to donate their blood stem cells to a blood cancer patient in need.

Focussed on helping patients with blood cancer and other blood disorders, DKMS-BMST has been able to save28unique lives in this period of one year including children diagnosed with blood cancer and other blood disorders like thalassemia.

Patients affected by blood cancer or thalassemia need a blood stem cell donation. Worldwide, only 30 per cent of them can find a match within their families and hence there is a dire need to find an unrelated donor. We started our operations in India last year with an intent to add potential blood stem cell donors of Indian ethnicity to the global database, so that patients (especially from this unique ethnicity) living in different parts of the world have a fair chance of finding a match and probably gain a second chance at life. We cannot thank enough, the people who are on-board and are helping us spread the word to add more and more people to this database,said Paul Patrick, CEO, DKMS BMST Foundation India.

Sharing his experience Mohd Saifulla, father to a 4-year-old thalassemia survivor said We went to multiple doctors trying to assess the problem our child had and thereafter to find a matching donor who could save her life. Receiving this transplant was the only chance of life for my daughter and we can never thank Debojyoti, a 28 year old software professional, enough, who donated his blood stem cells that matched our daughter. It is only because of organisations such as DKMS-BMST that people are coming forward to donate blood stem cells and save a life. My entire family is indebted to them for lifetime. Today my daughter is living a happy and healthy life and we are preparing to celebrate her fifth birthday this year that seemed like a dream to us up till a few years back.

Last year on World Blood Cancer Day, DKMS, one of the largest international blood stem cell donor centres in the world dedicated to the fight against blood cancer and blood disorders joined forces with Bangalore Medical Service Trust (BMST), a centre of excellence in blood banking, transfusion and immunohaematology adding India to the largest global repository of potential blood stem cell donors in the world. Every year, over 100,000 people in India are diagnosed with blood cancer or a blood disorder such asthalassemia or aplastic anaemia. Such life-threatening conditions can be managed by infusing a set of healthy blood stem cells from a suitable match. Since,ethnicity plays a crucial role in finding a matching donor, the ratio of potential blood stem cell donors from India needs to rise significantly, said Dr Latha Jagannathan, Director, DKMS BMST Foundation India.

Harsh, a blood stem cell donor registered with the foundation said,With very limited knowledge about blood stem cells I believed they were present only in the bone marrow and extracting them was a complex process. But to my surprise, the process is very similar to blood platelet donation. I strongly feel that anyone who is made aware that a simple process with zero complications can give you a chance to save a life will not hesitate from committing themselves towards the cause.

Capturing the challenges, the NGO faced in the country,Patrick said,We realised very early in India that a decision of this nature is not alone of the donor, but also involves his / her family. Hence, explaining the process, inculcating right awareness to break myths, updating people on the technological advances of blood stem cell donation and counselling them with medical experts has been our modus operandi in the country. Thus far, we have been able to conduct many physical drives to reach out to people urging them to register as potential donors. We plan to expand our reach to many more regions this year so that we are able to add potential donors from varied population groups in the country.

DKMS-BMST has organised over 1000donor registration drives in one year across various organisations such as corporates, educational institutes, hospitals and defence forces to spread awareness about blood stem cell donation and enroll more potential donors. Few names where physical drives have been conducted includes Mindtree, HSBC, HP enterprises, Christ University, RV College of Engineering, apart from public drives at Orion Mall Bengaluru, Lalbagh Botanical Garden etc.

In the current lockdown situation, the team is working tirelessly to ensure that patients whose donations were scheduled do not face any challenges and are organising awareness sessions through webinars and calling for registrations through the online portal:www.dkms-bmst.org/register.

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DKMS-BMST Foundation India completes one year of operation in India - Express Healthcare

World Blood Cancer Day 2020: Bring down your risk of this condition with easy diet tips – TheHealthSite

Bloodcanceris one of the most common types of cancer that generally affects people of all age groups. According to a report published by WHOs International Agency for Research on Cancer, India has the third-highest number of haematologicalcancers,popularly known as blood cancer. There was a time when cancer was considered an incurable disease, but over the recent years, the situations have changed drastically with the evolution in medical technology. This has made cancer treatments possible with up to 90 per cent survival chances. The World Blood Cancer Day is observed every year on May 28th around the world to show support for blood cancer patients. According to experts, early diagnosis in cancer, especially blood cancer, increases the chance of survival, thanks to evolved treatment modalities of the modern times. Also Read - World Blood Cancer Day 2020: Understanding the types and symptoms

Mostly, heamatological cancers originate in bone marrow, where blood is produced. This condition occurs when faulty blood cells affect the function of the normal ones that fend off infections and generate new cells. There are three types of blood cancers leukaemia, lymphoma and myeloma. In leukaemia, your body develops too many abnormal white blood cells (leukocytes) and makes it tough for your bone marrow to produce red blood cells. Lymphoma occurs when in the lymphocites while myeloma has its origin in the plasma cells of the blood. These are white blood cells produced in your bone marrow. Also Read - Researchers discover role of mutation in blood cancers

The prominent symptoms of blood cancer include chills, fatigue and weakness, night sweats, pain in the bones and joints, and swollen lymph nodes. It takes a toll on your immunity, making you susceptible to various infections and other conditions. Cancer also affects the rate at which your blood clots. So, small cuts or injuries may tend to bleed for a longer period of time. You may also experience unusual bruising, bleeding of the gums, and blood in stool. Women may go through heavy bleeding during their periods. Also Read - Today health tips: 6 lifestyle modifications to bring down your breast cancer risk

Experts are of the opinion that lymphoma in adults is 80-90 per cent curable and acute leukaemia in adults can be 40-50 per cent curable. However, many of the myeloma cases are incurable. The treatment for blood cancer mostly depends on the type of cancer, age of the patient and the severity of the cancer. On the basis of these factors, doctors may suggest chemotherapy, supportive care, stem cell transplantation, etc.

According to the guidelines of the American Oncology Institute, one can decrease the risk of blood can by following certain lifestyle measures. They include exercising regularly, eating healthy, avoiding exposure to herbicides, insecticides and radiations. Here are some simple dietary tips to bring down your chance of falling prey to this condition.

Eat generous amounts of vegetables and fruits, salads, beans and cereals in your diet. This will try increase your immunity.

These acids have anti-cancer properties. The best food sources could be fish, walnuts, soya bean, so on and so forth. You can also opt for fish oil supplements.

An antioxidant known as lycopene is present in tomatoes. It comes with cancer fighting properties. The best way to get lycopene from tomatoes is to heat them well. So, tomato soup can be a good option. You can also have it with other anti-oxidant rich veggies in the form of a salad.

Several studies have associated high intake of olive oil with cancer risk reduction. You can have this oil in your salads or sprinkle it on cooked veggies too. Also, try using olive oil while marinating your meat, fish or poultry.

Published : May 28, 2020 12:30 pm | Updated:May 28, 2020 1:17 pm

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World Blood Cancer Day 2020: Bring down your risk of this condition with easy diet tips - TheHealthSite

Studying the development of ovarian cancer with organoids – Science Codex

Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions of the female reproductive organs of the mouse. They found out that the cells of the oviduct, the equivalent of fallopian tubes in humans, are more prone to develop into tumors than those of the ovarian surface epithelium, the outer layer of the ovaries. In the future, such mini-versions, or organoids, of human tissue may be used to better understand how this disease, that is often diagnosed very late, develops. The researchers published their results in the scientific journal Nature Communications on the 27th of May.

High-grade serous ovarian cancer (hereafter referred to as simply "ovarian cancer") is the most common type of ovarian cancer and has the lowest rate of survival. It is often only diagnosed when it has already spread within the pelvis and abdomen, making it harder to treat. Because the early stages of ovarian cancer are not often observed, much is still unknown about the early development of the disease. We do know that ovarian cancer cells often have mutations, or mistakes, in certain genes, such as Trp53, a gene that is often mutated in many types of cancer, Brca1, a gene often mutated in breast cancer, Nf1 and Pten.

Organoids

Researchers in the group of Hans Clevers at the Hubrecht Institute used mini-versions of two parts of female reproductive tract of mice to study the early development of ovarian cancer. They grew mini-versions, or organoids, of the oviducts (in humans called the fallopian tubes) that transport the egg from the ovary to the uterus, and of the ovarian surface epithelium, the outer layer of the ovaries, in the lab from small pieces of tissue from mice. In these organoids, they recreated the mutations found in ovarian cancer. Using the state-of-the-art CRISPR-Cas9 genome editing approach, they mutated the genes Trp53, Brca1, Nf1 and Pten to study how these genes contribute to the development of a tumor.

Mutations

When mutations were introduced in three of the four genes, namely Trp53, Brca1 and either Nf1 or Pten, the organoids acquired characteristics of tumors, such as more densely packed cells and changes in chromosome number. In addition, when these organoids were transplanted back into mice, they developed into tumors that are similar to ovarian cancer tumors in humans.

The researchers found out that organoids from the oviduct were more likely to develop into tumors, grew faster and grew into larger tumors than the organoids from the ovarian surface epithelium. This suggests that ovarian cancer is more likely to originate in the oviduct, or the fallopian tube in humans, compared to the ovarian surface epithelium.

Earlier diagnosis and preventive care

Studying the development and progress of ovarian cancer in such organoid models may help to better understand how ovarian cancer develops in the body. Researchers in the group of Hans Clevers have previously shown that organoids can also be made from the human fallopian tube and the human ovarian surface epithelium. In the future, the researchers may also introduce the specific mutations found in ovarian cancer in these human organoids to further study the development of this disease.

Patients with a mutation in one of the Brca genes are at a high risk of ovarian cancer and can receive preventive treatment. This includes radical surgery in which both ovaries as well as the fallopian tubes are removed, leading to premature menopause in these women. The results in this study support the emerging view that the fallopian tube, not the ovarian surface epithelium around the ovaries, are the main origin for ovarian cancer, which may direct future changes in (preventive) treatment. For example, the Dutch Gynecological Oncology Group recently launched a clinical trial to study whether early removal of only the fallopian tubes and later removal of the ovaries can improve the quality of life for these patients, while also reducing the risk of ovarian cancer.

Knowing more about the development and progression of ovarian cancer may help doctors to better recognize ovarian cancer in the future, enabling earlier treatment and a higher chance of survival.

Publication

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids. Kadi Lhmussaar*, Oded Kopper*, Jeroen Korving, Harry Begthel, Celien P. H. Vreuls, Johan H. van Es, Hans Clevers. Nature Communications 2020.

*These authors contributed equally to this work

Hans Clevers is group leader at the Hubrecht Institute and the Princess Mxima Center for Pediatric Oncology, professor of Molecular Genetics at the UMC Utrecht and Utrecht University, and Oncode Investigator.

About the Hubrecht Institute

The Hubrecht Institute is a research institute focused on developmental and stem cell biology. It encompasses 23 research groups that perform fundamental and multidisciplinary research, both in healthy systems and disease models. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on Utrecht Science Park. Since 2008, the institute is affiliated with the UMC Utrecht, advancing the translation of research to the clinic. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL). For more information, visit http://www.hubrecht.eu.

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Studying the development of ovarian cancer with organoids - Science Codex

Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market 2020 Strategically Analysis of Each Submarket With Respect To Individual Growth…

Latest Report On Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market including Market Landscape, and Market size, Revenues by players, Revenues by regions, Average prices, Competitive landscape, market Dynamics and industry trends and developments during the forecast period.

The global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market is broadly analyzed in this report that sheds light on critical aspects such as the vendor landscape, competitive strategies, market dynamics, and regional analysis. The report helps readers to clearly understand the current and future status of the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market. The research study comes out as a compilation of useful guidelines for players to secure a position of strength in the global market. The authors of the report profile leading companies of the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market, Also the details about important activities of leading players in the competitive landscape.

Key companies operating in the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market include: , Orange County Hair Restoration Center, Hair Sciences Center of Colorado, Anderson Center for Hair, Evolution Hair Loss Institute, Savola Aesthetic Dermatology Center, Virginia Surgical Center, Hair Transplant Institute of Miami, Colorado Surgical Center & Hair Institute

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The report predicts the size of the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market in terms of value and volume for the forecast period 2020-2026. As per the analysis provided in the report, the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market is expected to rise at a CAGR of xx % between 2020 and 2026 to reach a valuation of US$ xx million/billion by the end of 2026. In 2020, the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market attained a valuation of US$ XX million/billion. The market researchers deeply analyze the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies industry landscape and the future prospects it is anticipated to create

Segmental Analysis

The report has classified the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies manufacturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies industry.

Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Segment By Type:

Platelet Rich Plasma Injections, Stem Cell Therapy

Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Segment By Application:

Dermatology Clinics, Hospitals

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies industry. In order to fulfill the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market include: , Orange County Hair Restoration Center, Hair Sciences Center of Colorado, Anderson Center for Hair, Evolution Hair Loss Institute, Savola Aesthetic Dermatology Center, Virginia Surgical Center, Hair Transplant Institute of Miami, Colorado Surgical Center & Hair Institute

Key questions answered in the report:

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TOC

Table of Contents Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Report by Company, Regions, Types and Applications, Global Status and Forecast to 2025 1 Industry Overview of Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies1.1 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Overview1.1.1 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Product Scope1.1.2 Market Status and Outlook1.2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Analysis by Regions1.2.1 North America1.2.2 Europe1.2.3 China1.2.4 Rest of Asia Pacific1.2.5 Central & South America1.2.6 Middle East & Africa1.3 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market by Type1.3.1 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Million US$) and Growth Comparison by Type (2014-2025)1.3.2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue Market Share by Type in 20181.3.3 Platelet Rich Plasma Injections1.3.4 Stem Cell Therapy1.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market by End Users/Application1.4.1 Dermatology Clinics1.4.2 Hospitals 2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Competition Analysis by Players2.1 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (Million US$) by Players (2014-2019)2.2 Competitive Status2.2.1 Market Concentration Rate2.2.2 Product/Service Differences2.2.3 Mergers & Acquisitions, Expansion Plans 3 Company (Top Players) Profiles and Key Data3.1 Orange County Hair Restoration Center3.1.1 Company Profile3.1.2 Main Business/Business Overview3.1.3 Products, Services and Solutions3.1.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.1.5 Recent Developments3.2 Hair Sciences Center of Colorado3.2.1 Company Profile3.2.2 Main Business/Business Overview3.2.3 Products, Services and Solutions3.2.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.2.5 Recent Developments3.3 Anderson Center for Hair3.3.1 Company Profile3.3.2 Main Business/Business Overview3.3.3 Products, Services and Solutions3.3.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.3.5 Recent Developments3.4 Evolution Hair Loss Institute3.4.1 Company Profile3.4.2 Main Business/Business Overview3.4.3 Products, Services and Solutions3.4.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.4.5 Recent Developments3.5 Savola Aesthetic Dermatology Center3.5.1 Company Profile3.5.2 Main Business/Business Overview3.5.3 Products, Services and Solutions3.5.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.5.5 Recent Developments3.6 Virginia Surgical Center3.6.1 Company Profile3.6.2 Main Business/Business Overview3.6.3 Products, Services and Solutions3.6.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.6.5 Recent Developments3.7 Hair Transplant Institute of Miami3.7.1 Company Profile3.7.2 Main Business/Business Overview3.7.3 Products, Services and Solutions3.7.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.7.5 Recent Developments3.8 Colorado Surgical Center & Hair Institute3.8.1 Company Profile3.8.2 Main Business/Business Overview3.8.3 Products, Services and Solutions3.8.4 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue (Value) (2014-2019)3.8.5 Recent Developments 4 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Type and Application (2014-2019)4.1 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Type (2014-2019)4.2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019)4.3 Potential Application of Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies in Future4.4 Top Consumer/End Users of Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies 5 North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook5.1 North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)5.2 North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)5.3 North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 6 Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook6.1 Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)6.2 Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)6.3 Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 7 China Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook7.1 China Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)7.2 China Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)7.3 China Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 8 Rest of Asia Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook8.1 Rest of Asia Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)8.2 Rest of Asia Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)8.3 Rest of Asia Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 9 Central & South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook9.1 Central & South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)9.2 Central & South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)9.3 Central & South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 10 Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Development Status and Outlook10.1 Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size (2014-2019)10.2 Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size and Market Share by Players (2014-2019)10.3 Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2014-2019) 11 Market Forecast by Regions and Application (2019-2025)11.1 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Regions (2019-2025)11.1.1 North America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.1.2 Europe Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.1.3 China Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.1.4 Rest of Asia Pacific Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.1.5 Central & South America Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.1.6 Middle East & Africa Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Revenue and Growth Rate (2019-2025)11.2 Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Size by Application (2019-2025)11.3 The Market Drivers in Future 12 Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market Dynamics12.1 Industry Trends12.2 Market Drivers12.3 Market Challenges12.4 Porters Five Forces Analysis 13 Research Finding /Conclusion 14 Methodology and Data Source14.1 Methodology/Research Approach14.1.1 Research Programs/Design14.1.2 Market Size Estimation14.1.3 Market Breakdown and Data Triangulation14.2 Data Source14.2.1 Secondary Sources14.2.2 Primary Sources14.3 Disclaimer14.4 Author List

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10 Things You Should Know About Dermal Fillers Before Getting Them Our Interview With Dr Nicholas Toscano On Juvederm – CelebMix

Dermal fillers are a popular choice for obtaining perfect lips or smoother skin, and we find out everything you need to know about them.

By Vicky Sidler

If youre looking for smoother skin, fuller cheeks, or plumper lips, youve likely read about dermal fillers quick, injectable treatments that can restore lost volume to your lips and cheeks. These minimally invasive procedures are designed to be long-lasting while looking completely natural, and they can have a rejuvenating effect on your appearance.

The procedure is also very low-risk, provided you go to a reputable doctor. As such, we spoke to Dr. Nicholas Toscano to find out everything you need to know about dermal fillers, from what to expect during the procedure to how to choose someone reliable to administer the fillers.

Dr. Toscano is responsible for some of the most beautiful lips in the modeling world, which he creates utilizing Juvderm lip fillers and platelet-rich plasma/platelet-rich fibrin know as the Dracula injection. He is currently the official dentist for roughly 20 modeling agencies in New York City, including The Lions, Wilhelmina, One Model Management, Heroes, Muse, Marilyn, Storm, Major models, Fusion, System, State, and others.

Juvderm fillers differ from Botox in that its not a neurotoxin. Instead, dermal fillers use hyaluronic acid, which is naturally found in the skin and gives you a radiant, hydrated appearance. Hyaluronic acid production decreases as you age, so these injections work well to restore lost volume to key parts of your face, such as your lips.

The procedure shouldnt be painful if it is carried out by a skilled doctor. The fillers contain a local anesthetic, and so no additional anesthetic is required during a basic dermal filler procedure. The simple, straight-forward takes between 15 and 30 minutes and involves only a few tiny injections directly into the skin. Youre able to apply makeup straight after the procedure and go back to work right away.

Youll be able to see the results of the procedure immediately. For best results, though, you will need to maintain your fillers over time through regular, repeated treatments.

A single treatment can make your lips plumper and your skin smoother for up to six months. Typically, results last between three to six months before a touch up is needed so you can expect to visit your doctor two or three times a year to maintain your look. If youre only looking to try fillers out once or twice, you can skip the maintenance without experiencing any long-term risks. The effects will fade away entirely and safely.

Fillers dont only need to be used to treat existing lines. They offer protection against developing lines as well, so dermal fillers can be used as a preventative measure against wrinkles. Research suggests that injectable hyaluronic acid-based dermal fillers can stimulate your skins collagen production, helping you to look younger for longer.

While the procedure is safe, its not a good idea to have the injections if you are pregnant or breastfeeding. Nor should you go if you have a sinus infection or are about to undergo a dental treatment since the pressure and stretching of the face could cause the fillers to become misplaced. Instead, wait a week or so before undergoing the procedure.

If you dont like the way your filler looks or if you want them adjusted, in most cases, it wont be a problem at all. Your doctor may inject additional filler to achieve the desired effect, or theres an enzyme for hyaluronic acid fillers that can be used to dissolve the filler completely and safely.

The last thing you want is to look like you had work done. Dermal fillers should look completely natural they should emphasize your beauty in a way thats impossible to pinpoint. The goal is for it to be imperceptible. Imagine that your face is a canvas and that you are looking for an artist whose work you like. Be sure to ask for before-and-after photos of real patients to get a good idea of the doctors style. Also, be sure to ask about their techniques, levels of experience, and your specific needs.

One of the biggest mistakes you can make is to get lured in by a price that seems too good to be true because it probably is. Treatments range between $650 to $2,000 depending on the amount of filler needed. Anything under that should cause you to ask questions. A syringe of filler costs doctors between $250 and $350, so no treatment should ever be priced at around that mark or lower. Counterfeit and diluted fillers are also a problem in the industry, so its essential that you find a reputable doctor (as explained in the point above). If you have any concerns at all, it might be a good idea to ask to see the box and ensure that it has a safety seal intact.

Dr. Nicholas Toscano is an extremely accomplished and highly respected dental surgeon with a rich career of experience. He spent 13 years with the United States Navy, where he completed a 4-year surgical residency at the prestigious Walter Reed National Military Medical Center, The Presidents Hospital in Bethesda, MD.

During his time in the Navy, he received two Navy and Marine Corps Commendation Medals, three Navy and Marine Corps Achievement Medals, a National Defense Service Medal, and Global War on Terrorism Medal. He acquired one of his Navy and Marine Corps Commendation Medal for definitive life-saving treatment of a patient.

He is also a diplomate of the American Board of Periodontology and the International Congress of Implantologists, and he has written over 30 papers published in peer-reviewed scientific journals on the subject of surgical therapy, cosmetic, and reconstruction of the mouth.

His long and established career, along with his glamorous list of happy customers, makes him the dentist of choice in New York City. His client list display the kinds of smiles that will have you doing a double-take, including the gorgeous Victorias Secret models, such as Candice Swanepoel, Helena Christensen, Jasmine Tookes, Romee Strijd, Josephine Skriver, Georgia Fowler, Frida Aasen, Vittoria Ceretti, Megan Williams, Lais Ribeiro, Daniela Braga, and Blanca Padilla. To make an appointment with Dr. Nicholas Toscano to discuss the option of dental implants or any other services, visit Instagram @drtoscanodds or his website http://www.manhattanperiodontist.com.

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10 Things You Should Know About Dermal Fillers Before Getting Them Our Interview With Dr Nicholas Toscano On Juvederm - CelebMix

EdiGene and Immunochina Announce Research and Development Collaboration to Develop Allogeneic CAR-T Therapy for Cancer – Business Wire

BEIJING, China & CAMBRIDGE, Mass.--(BUSINESS WIRE)--EdiGene, Inc., which develops genome editing technologies to accelerate drug discovery and develop novel therapeutics for a broad range of diseases, and Immunochinaa company dedicated to innovative gene and cellular technology today announced that they have formed a research and development collaboration to develop allogeneic CAR-T therapy for cancer.

Under this partnership, both companies will combine EdiGenes expertise in genome editing and allogeneic T-cell process with Immunochinas expertise in innovative CAR-T technology to develop potentially best-in-class allogeneic CAR-T therapeutics. Terms are not disclosed.

"EdiGene is a leading gene-editing company with cutting edge technology platform. It is our great pleasure to work with this team," said Ting He, Ph.D.founder and CEO of Immunochina, "Make the Incurable Curable, which is Immunochinas vision. We have accumulated considerable experience in late-stage hematological malignancies, with two IND approvals. Although a number of break throughs have been made by autologous T cells lately, allogeneic T cells could also play an important role in the future. The cooperation is a big step for both teams, and I believe we will make exciting discoveries together."

We are excited to collaborate with Immunochina, one of the leading clinical-stage CAR-T companies, said Dong Wei, Ph.D.CEO of EdiGene, We believe that allogeneic T-cell therapeutics has tremendous potential, by offering innovative T-cell therapies off the shelf with more effective quality control and lower cost. By combining the expertise of EdiGene and Immunochina, we will be well positioned to develop such therapeutics and advance to clinics, one step closer to help the cancer patients in need.

About EdiGene, Inc

EdiGene is a biotechnology company focused on leveraging the cutting-edge genome editing technologies to accelerate drug discovery and develop novel therapeutics for a broad range of genetic diseases and cancer. The company has established its proprietary ex vivo genome-editing platforms for hematopoietic stem cells and T cells, in vivo therapeutic platform based on RNA base editing, and high-throughput genome-editing screening to discover novel targeted therapies. Founded in 2015, EdiGene is headquartered in Beijing, with subsidiaries in Guangzhou, China and Cambridge, Massachusetts, USA. More information can be found at http://www.edigene.com.

About Immunochina

Immunochina is committed to the application of innovative gene and cellular technology for treatment of lethal diseases. The company owns integrated CAR-T platform, including core technologies such as large-scale viral vector production and primary immune cell processing. The pipeline includes several CAR-T candidates for treatment of advanced cancer, with two IND approvals. Founded in 2015, Immunochina is headquartered in Beijing. More information can be found at http://www.immunochina.com

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EdiGene and Immunochina Announce Research and Development Collaboration to Develop Allogeneic CAR-T Therapy for Cancer - Business Wire

Precision Medicine Market 2020: Industry Analysis and Detailed Profiles of Top Industry Players are Neon Therapeutics, Moderna, Inc, Merck & Co.,…

Global Precision Medicine market report provides an in-depth overview of Product Specification, technology, product type and production analysis considering major factors such as Revenue, Cost, Gross and Gross Margin. The company profiles of all the key players and brands that are dominating the Precision Medicine market with moves like product launches, joint ventures, merges and accusations which in turn is affecting the sales, import, export, revenue and CAGR values are mentioned in the report. The report is generated based on the market type, size of the organization, availability on-premises and the end-users organization type, and the availability in areas such as North America, South America, Europe, Asia-Pacific and Middle East & Africa.

Global Precision Medicine Marketto grow with a substantial CAGR in the forecast period of 2019-2026. Growing prevalence of cancer worldwide and accelerating demand of novel therapies to prevent of cancer related disorders are the key factors for lucrative growth of market

Key Market Players:

Few of the major competitors currently working in the global precision medicine market are Neon Therapeutics, Moderna, Inc, Merck & Co., Inc, Bayer AG, PERSONALIS INC, GENOCEA BIOSCIENCES, INC., F. Hoffmann-La Roche Ltd, CureVac AG, CELLDEX THERAPEUTICS, BIONTECH SE, Advaxis, Inc, GlaxoSmithKline plc, Bioven International Sdn Bhd, Agenus Inc., Immatics Biotechnologies GmbH, Immunovative Therapies, Bristol-Myers Squibb Company, Gritstone Oncology, NantKwest, Inc among others.

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Global Precision Medicine MarketBy Application (Diagnostics, Therapeutics and Others), Technologies (Pharmacogenomics, Point-of-Care Testing, Stem Cell Therapy, Pharmacoproteomics and Others), Indication (Oncology, Central Nervous System (CNS) Disorders, Immunology Disorders, Respiratory Disorders, Others), Drugs (Alectinib, Osimertinib, Mepolizumab,Aripiprazole lauroxil and Others), Route of Administration (Oral,Injectable), End- Users (Hospitals, Homecare, Specialty Clinics, Others), Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) Industry Trends and Forecast to 2026

Competitive Analysis:

The precision medicine market is highly fragmented and is based on new product launches and clinical results of products. Hence the major players have used various strategies such as new product launches, clinical trials, market initiatives, high expense on research and development, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of mass spectrometry market for global, Europe, North America, Asia Pacific and South America.

Market Drivers

Market Restraints

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Market Definition:

Precision medicines is also known as personalized medicines is an innovative approach to the patient care for disease treatment, diagnosis and prevention base on the persons individual genes. It allows doctors or physicians to select treatment option based on the patients genetic understanding of their disease.

According to the data published in PerMedCoalition, it was estimated that the USFDA has approved 25 novels personalized medicines in the year of 2018. These growing approvals annually by the regulatory authorities and rise in oncology and CNS disorders worldwide are the key factors for market growth.

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Key Developments in the Market:

Competitive Analysis:

Global precision medicine market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of global precision medicine market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Market Segmentation:

By technology:-big data analytics, bioinformatics, gene sequencing, drug discovery, companion diagnostics, and others.

By application:- oncology, hematology, infectious diseases, cardiology, neurology, endocrinology, pulmonary diseases, ophthalmology, metabolic diseases, pharmagenomics, and others.

On the basis of end-users:- pharmaceuticals, biotechnology, diagnostic companies, laboratories, and healthcare it specialist.

On the basis of geography:- North America & South America, Europe, Asia-Pacific, and Middle East & Africa. U.S., Canada, Germany, France, U.K., Netherlands, Switzerland, Turkey, Russia, China, India, South Korea, Japan, Australia, Singapore, Saudi Arabia, South Africa, and Brazil among others.

In 2017, North America is expected to dominate the market.

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Data Bridge Market Researchset forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.

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Precision Medicine Market 2020: Industry Analysis and Detailed Profiles of Top Industry Players are Neon Therapeutics, Moderna, Inc, Merck & Co.,...

Vegan diet, intense cardio and stem cell therapy How Mike Tyson managed to get ripped at 53 as boxing c – talkSPORT.com

Mike Tyson has attributed his incredible body transformation to stem cell therapy and a rigid vegan diet.

The youngest world heavyweight champion in history ballooned to more than 300lbs in weight at his heaviest almost a decade ago.

However, after drastically changing his diet and implementing revolutionary reparative medication, Iron Mike is looking more streamlined and more devastating than ever.

Tyson is reportedly considering making a return to the squared circle at the age of 53, with an announcement on his opponent expected this week.

Whilst training with UFC legends Vitor Belfort and Henry Cejudo, the former undisputed heavyweight champion displayed a significantly more shredded physique.

Prior to officially announcing his desire to return, Tyson was asked by rapper LL Cool J how he would get fighting fit in just six to eight weeks.

He told Rock the Bells Radio show on SiriusXM: Really I would just change my diet and just do cardio work. Cardio has to start, you have to have your endurance to go and do the process of training.

Mike Tyson

So something to do is get in cardio, I would try and get two hours of cardio a day, make sure you get that stuff in. Youre gonna make sure youre eating the right food.

For me its almost like slave food. Doing what you hate to do but doing it like its nothing. Getting up when you dont want to get up. Thats what it is. Its becoming a slave to life.

People think a slave to life is just enjoying drugs and living your life. Being a slave to life means being the best person you can be, being the best you can possibly be, and when you are at the best you can possibly be is when you no longer exist and nobody talks about you. Thats when youre at your best.

Tyson continued: My mind wouldnt belong to me. My mind would belong to somebody that disliked me enough to break my soul, and I would give them my mind for that period of time.

Six weeks of this and Id be in the best shape Ive ever dreamed of being in. As a matter of fact, Im going through that process right now. And you know what else I did, I did stem-cell research.

Stem-cell research (also known as regenerative medicine) promotes the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives.

It is the latest advancement in organ transplantation and uses cells instead of donor organs, which are limited in supply.

After LL Cool J asked if that meant Tysons white blood cells had been spun and then put back in, Tyson continued: Yes. As they took the blood it was red and when it came back it was almost transfluid [sic], I could almost see through the blood, and then they injected it in me. And Ive been weird ever since, Ive got to get balanced now.

Getty Images - Getty

The necessity to repair the former heavyweight champion was caused by the excessive weight gain following his retirement in 2005 and his hedonistic lifestyle.

Excessive cocaine abuse left the heavyweight in a serious state of bother and led him to adopt a vegan lifestyle.

He told Totally Vegan Buzz: I was so congested from all the drugs and bad cocaine, I could hardly breathe. Tyson also revealed in the interview, I had high blood pressure, was almost dying, and had arthritis.

During aninterviewwith Oprah Winfrey in 2013, Tysoncredits his plant-based diet for saving his life.

Getty Images

He said: Well, my life is different today because I have stability in my life. Im not on drugs.

Im not out on the streets or in clubs and everything in my life that I do now is structured around the development of my life and my family. I lost weight.

I dropped over 100lbs and I just felt like changing my life, doing something different and I became a vegan.

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Vegan diet, intense cardio and stem cell therapy How Mike Tyson managed to get ripped at 53 as boxing c - talkSPORT.com

Hair regeneration using stem cells to treat baldness – BioNews

26 May 2020

Stem cells derived from fat can lead to hair regrowth for people with a common type of baldness, according to a new study.

The South Korean researchersconducted a clinical trial into androgenetic alopecia (AGA), the most common cause of hair loss. The trial showed that the use of extracts of fat tissue termed adipose-derived stem cell constituent extract (ADSC-CE) increasedboth hair thickness and density in patients.

'Recent studies have shown that ADSCs promote hair growth in both men and women with alopecia. However, no randomised, placebo-controlled trial in humans has explored the effects and safety of ADSC-CE in AGA. We aimed to assess the efficacy and tolerability of ADSC-CE in middle-aged patients with AGA in our study, hypothesising that it is an effective and safe treatment agent,' said corresponding author Dr Sang Lee from Pusan National University Yangsan Hospital.

To make their solution, the team disrupted the membrane of stem cells found in fat tissues using a low-frequency ultrasound wave and enriched the secreted stem cell with protein. They recruited 38 patients 29 men and nine women with AGA for the clinical trial. One half applied the ADSC-CE lotion to their scalp with their fingers, and the other applied a placebo solution.

A dot was tattooed on the participants'scalps in order to compare the same spot over time. After 16 weeks, the group that used the ADSC-CE lotion presented a significant increase in hair density with 28.1 percent in comparison to 7.1 percent in the control group, and also hair thickness with 14.2 percent in comparison to 6.3 percent in the control group.

The results from this clinical trial, published in the journal Stem Cells Translational Medicine, presented no side-effects, and provide an alternative to current hair therapeutic strategies that have been associated with loss of libido and erectile disfunction.

Further research is required to understand the molecular mechanisms by which ADSC-CE can affect hair growth in humans. 'The next step should be to conduct similar studies with large and diverse populations in order to confirm the beneficial effects of ADSC-CE on hair growth and elucidate the mechanisms responsible for the action of ADSC-CE in humans,' said Dr Lee.

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Hair regeneration using stem cells to treat baldness - BioNews

Human Embryonic Stem Cell Market Analysis with Key Players, Applications, Trends and Forecast to 2027 – Jewish Life News

The Covid-19 (coronavirus) pandemic is impacting society and the overall economy across the world. The impact of this pandemic is growing day by day as well as affecting the supply chain. The COVID-19 crisis is creating uncertainty in the stock market, massive slowing of supply chain, falling business confidence, and increasing panic among the customer segments. The overall effect of the pandemic is impacting the production process of several industries including Life Science, and many more. Trade barriers are further restraining the demand- supply outlook.

The human embryonic stem cells are obtained from the undifferentiated inner mass cell of the human embryo and human fetal tissue. The human embryonic stem cell can replicate indefinitely and produce non-regenerative tissue such as myocardial and neural cells. This potential of human embryonic stem cell allows them to provide an unlimited amount of tissue for transplantation therapies to treat a wide range of degenerative diseases. Hence, human embryonic stem cells are used in the treatment of various diseases such as Alzheimers disease, cancer, blood and genetic disorders related to the immune system and others.

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The global human embryonic stem cell market is expected to grow in upcoming years, factors driving the growth of market are rise in incidences of neurological disorders, increase in investment by government and other organization for research activities, awareness among people about stem cell therapeutic potency for disease treatment. On the other hand emerging stem cell banking services is expected to offer lucrative opportunities in growth of human embryonic stem cell market.

Key Players Influencing the Market:

1. BD

2. Takara Bio Inc.

3. Geron

4. Thermo Fisher Scientific Inc.

5. ViaCyte, Inc.

6. R&D Systems, Inc.

7. QIAGEN

8. CellGenix GmbH

9. Vitrolife

10. Lonza

Market Segmentation :

The global human embryonic stem cell market is segmented on the basis of product type, application and end user. Based on product type, the market is segmented as totipotent stem cell, pluripotent stem cell and unipotent stem cell. On the basis of application, the global human embryonic stem cell market is segmented into regenerative medicine, stem cell biology research, tissue engineering and toxicology testing. Based on end users, the market is segmented as therapeutics companies, cell & tissue banks, tools & reagents companies and others.

The report provides a detailed overview of the industry including both qualitative and quantitative information. It provides overview and forecast of the global human embryonic stem cell market based on various segments. It also provides market size and forecast estimates from year 2017 to 2027 with respect to five major regions, namely; North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South & Central America. The human embryonic stem cell market by each region is later sub-segmented by respective countries and segments. The report covers analysis and forecast of 18 countries globally along with current trend and opportunities prevailing in the region.

The report analyzes factors affecting human embryonic stem cell market from both demand and supply side and further evaluates market dynamics effecting the market during the forecast period i.e., drivers, restraints, opportunities and future trend. The report also provides exhaustive PEST analysis for all five regions namely; North America, Europe, APAC, MEA and South & Central America after evaluating political, economic, social and technological factors effecting the human embryonic stem cell market in these regions.

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Human Embryonic Stem Cell Market Analysis with Key Players, Applications, Trends and Forecast to 2027 - Jewish Life News