Stem Cell Clinic

Global Autologous Cell Therapy Market 2020-2024 | Evolving Opportunities with Bayer AG and Brainstorm Cell Therapeutics Inc. | Technavio – Business…

By adminMarch 28, 2020Stem Cell Treatment

LONDON--(BUSINESS WIRE)--The global autologous cell therapy market is poised to grow by USD 1.97 billion during 2020-2024, progressing at a CAGR of almost 22% during the forecast period. Request free sample pages

Read the 120-page report with TOC on "Autologous Cell Therapy Market Analysis Report by Therapy (Autologous stem cell therapy and Autologous cellular immunotherapies), Application (Oncology, Musculoskeletal disorders, and Dermatology), Geography (North America, APAC, Europe, South America, and MEA), and the Segment Forecasts, 2020-2024".

https://www.technavio.com/report/autologous-cell-therapy-market-industry-analysis

The market is driven by the increasing demand for effective drugs for cardiac and degenerative disorders. In addition, the limitations in traditional organ transplantations are fueling the demand for stem cell therapies. All these factors are anticipated to boost the growth of the autologous cell therapy market.

The demand for effective drugs for cardiac and degenerative disorders has been increasing across the world. In addition, the discovery of possible cardiac autologous cells has enabled vendors to develop novel drugs for the treatment of various cardiac diseases. For instance, Mesoblast is developing MPC-150-IM. It is a Phase III candidate for the treatment of advanced and end-stage chronic heart failure. Similarly, Shire has been developing autologous stem cell therapies for chronic myocardial ischemia. These products are expected to be launched during the forecast period and will have a positive impact on the growth of the global autologous cell therapy market.

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Major Five Autologous Cell Therapy Market Companies:

Bayer AG

Bayer AG operates its business through segments such as Pharmaceuticals, Crop Science, Consumer Health, and Animal Health. The company offers induced pluripotent stem cells. They are developed by reprogramming mature body cells to behave like embryonic stem cells that are injected to restore diseased tissue in patients.

Brainstorm Cell Therapeutics Inc.

Brainstorm Cell Therapeutics Inc. operates its business through an unified business segment. NurOwn is the key offering of the company. It is a cell therapy platform, which develops mesenchymal stem cells for the treatment of human diseases such as immune and inflammatory diseases.

Daiichi Sankyo Co. Ltd.

Daiichi Sankyo Co. Ltd. operates its business through segments such as Innovative Pharmaceuticals, Generic, Vaccine, and OTC Related. Heartcel is the key offering of the company. It is an immune-modulatory progenitor cell therapeutic agent, which is used for ischemic heart failure.

FUJIFILM Holdings Corp.

FUJIFILM Holdings Corp. operates its business through segments such as Imaging solutions, Healthcare and material solutions, and Document solutions. The company uses induced pluripotent stem cells to derive differentiated cells, which are used in researching various diseases and conditions.

Holostem Terapie Avanzate Srl

Holostem Terapie Avanzate Srl operates its business through an unified business segment. Holoclar is the key offering of the company. It is an advanced therapy medicinal product containing stem cells indicated to repair the cornea after injury.

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Autologous Cell Therapy Market Therapy Outlook (Revenue, USD Billion, 2020-2024)

Autologous Cell Therapy Market Application Outlook (Revenue, USD Billion, 2020-2024)

Autologous Cell Therapy Market Regional Outlook (Revenue, USD Billion, 2020-2024)

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Related Reports on Healthcare Include:

Global Cancer Stem Cell Therapeutics Market Global cancer stem cell therapy market by type (allogeneic stem cell transplant and autologous stem cell transplant) and geography (Asia, Europe, North America, and ROW).

Global Mantle Cell Lymphoma Therapeutics Market Global mantle cell lymphoma therapeutics market by product (combination therapy and monotherapy) and geography (Asia, Europe, North America, and ROW).

About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavios report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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Global Autologous Cell Therapy Market 2020-2024 | Evolving Opportunities with Bayer AG and Brainstorm Cell Therapeutics Inc. | Technavio - Business...

Global Hematopoietic Stem Cells Transplantation (HSCT) Market 2020-2024 | Evolving Opportunities with AllCells Corp. and bluebird bio Inc. | Technavio…

By adminMarch 28, 2020Stem Cell Treatment

LONDON--(BUSINESS WIRE)--The global hematopoietic stem cells transplantation (HSCT) market is poised to grow by USD 4.64 billion during 2020-2024, progressing at a CAGR of about 6% during the forecast period. Request free sample pages

Read the 120-page report with TOC on "Hematopoietic Stem Cells Transplantation (HSCT) Market Analysis Report by Type (Autologous HSCT and Allogeneic HSCT), Geographic segmentation (Asia, Europe, North America, and ROW), and the Segment Forecasts, 2020-2024".

https://www.technavio.com/report/hematopoietic-stem-cells-transplantation-market-industry-analysis

The market is driven by the availability of technologically advanced equipment. In addition, the growing demand for personalized medicine is anticipated to boost the growth of the hematopoietic stem cells transplantation (HSCT) market.

The increasing efforts on improving the success rates of HSCT procedure is encouraging the adoption of advanced technologies and sophisticated instruments. For instance, Marrow Cellution, a patented technology, was developed by Ranfac. This technology is gaining traction in the market as it addresses the issues associated with conventional transplant syringe. It prevents contamination of peripheral blood during transplantation. In addition, this technology allows high-quality stem and progenitor cells to harvest within a narrow space. Thus, the availability of technologically advanced equipment is expected to drive market growth during the forecast period.

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Major Five Hematopoietic Stem Cells Transplantation (HSCT) Market Companies:

AllCells Corp.

AllCells Corp. provides mobilized leukopak, bone marrow and cord blood, whole blood, and leukopak. They also offer Cord Blood, which are collected from a single umbilical cord. They are cryopreserved and offered in the format of isolated cells. Cord Blood products include progenitor cells and CD34 HSCs.

bluebird bio Inc.

bluebird bio Inc. focuses on research, development, and commercialization of potentially transformative gene therapies. The company provides Zynteglo, which is a medicine used to treat patients of 12 years and older who are affected by a blood disorder known as beta thalassaemia.

FUJIFILM Holdings Corp.

FUJIFILM Holdings Corp. operates under various business segments, namely Imaging solutions, Healthcare and material solutions, and Document solutions. The company offers iCell Hematopoietic Progenitor Cells 2.0.

Lineage Cell Therapeutics Inc.

Lineage Cell Therapeutics Inc. focuses on research and development of therapeutic products for blood plasma volume expansion, orthopedics, oncology, diagnostic products for the early detection of cancer, neurological diseases and disorders, and more. The company provides OpRegen, which is in Phase I/IIa clinical trial.

Lonza Group Ltd.

Lonza Group Ltd. offers products through the following business segments: Pharma Biotech and Nutrition and Specialty ingredients. The company offers a wide range of stem cells such as bone marrow stromal cells, human peripheral blood CD14+ monocytes, cryopreseverd human CD34+ cells isolated from single donor, osteoclast precusor, and more.

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Hematopoietic Stem Cells Transplantation (HSCT) Market Type Outlook (Revenue, USD Billion, 2020-2024)

Hematopoietic Stem Cells Transplantation (HSCT) Market Geographic Outlook (Revenue, USD Billion, 2020-2024)

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Related Reports on Health Care Include:

Allogeneic Stem Cells Market Global Allogeneic Stem Cells Market by geography (Asia, Europe, North America, and ROW) and application (regenerative therapy and drug discovery and development).

Cancer Stem Cell Therapeutics Market Global Cancer Stem Cell Therapeutics Market by type (allogeneic stem cell transplant and autologous stem cell transplant) and geography (Asia, Europe, North America, and ROW).

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Global Hematopoietic Stem Cells Transplantation (HSCT) Market 2020-2024 | Evolving Opportunities with AllCells Corp. and bluebird bio Inc. | Technavio...

HIV/AIDS cure: Second patient confirmed HIV-free and here’s the treatment that cured him – EconoTimes

By adminMarch 28, 2020Stem Cell Treatment

HIV/AIDS was believed to have been first detected in humans in 1959 and in 1982 public health officials coined the term "Acquired Immunodeficiency Syndrome" or AIDS to describe the infection, but in 1983, the term was changed to HIV (Human Immunodeficiency Virus) after researchers discovered the virus that causes the disease, as per the AIDS Institute.

Just like with any newly-discovered virus strains that make people ill, for decades, there was no known cure for HIV/AIDS and lots of people already died from it. But after 50 years, it seems that a cure has finally been found and it is all thanks to the scientists, doctors and researchers who continuously work to find treatment for it and end the fight against this communicable disease.

But then, since this is just new doctors are not exactly declaring that they have found a cure already. Even if there are patients who already walked away from the hospitals HIV/AIDS-free, medical professionals just stated that they are getting really closer to finally having the cure.

The first cured patient

Timothy Brown was not named at first and was only referred to as the Berlin Patient and he the first to be identified as cured from the disease. He was diagnosed with HIV/AIDS in 1995 and was free from the virus after undergoing a stem cell procedure.

Being cured through this treatment was actually accidental because when Brown was diagnosed, he received the typical course of action for HIV-positive patients which is the antiretroviral treatment. However, later he was also diagnosed to have acute myeloid leukemia that required him to undergo a stem cell transplant.

While searching for a donor, his doctor came up with an idea and started to look for donors with a kind of genetic mutation that made them immune to the sexually transmitted disease. After finding a match and the stem cell procedure went ahead, his doctor was astonished to discover that not only his leukemia but his HIV/AIDS infection was also cured.

In 2007, Brown went into HIV remission and up to now, he doesnt show any signs of the infection. His treatment was published in The New England Journal of Medicine on Feb. 12, 2009.

The second patient

Since doctors succeeded in curing Timothy Brown, they tried the procedure on other patients but they failed to achieve the same results. But in 2019, Adam Castillejo who was known as the London Patient was cured using the same stem cell treatment

He was diagnosed in 2003 and in 2012, developed advanced Hodgkins lymphoma. As his body was rejecting chemotherapy, his doctors suggested stem cell transplant and found a donor match with the rare CCR5 mutation called CCR5-delta 32 and the procedure was done in 2016.

He was observed for 18 months before doctors confirmed he is cured. His treatment and results were published in the world's oldest, most prestigious and well-known medical journal, The Lancet. With the promising developments, it gave the world some hopes that infected people will be cured using the same treatment, but scientists still have to refine everything to officially declare it as an HIV/AIDS cure.

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HIV/AIDS cure: Second patient confirmed HIV-free and here's the treatment that cured him - EconoTimes

Donald Trump Is Using An Insanely Sketchy Newsletter To Find Campaign Donors – The Union Journal

By adminMarch 28, 2020Stem Cell Treatment

The electronic newsletter I Love My Freedom on a regular basis blasts out e-mails hawking ostentatious rip-offs as well as serpent oil, such as a dementia-reversing miracle therapy, a diabetes destroyer material as well as a life-saving cancer cells treatment that a Nazi drug store allegedly established at Hitlers command. Peppered in between these messages funded by third-party hucksters are main advertisements from Donald Trumps governmental reelection campaign.

For months, participants of the head of states internal circle consisting of Donald Trump Jr., Senate Majority Leader Mitch McConnell (R-Ky), previous House Speaker Newt Gingrich as well as also Trump himself have actually been releasing require contributions with the newsletter, which usually heads out 5 or even more times each day. Many receivers were most likely unintentionally subscribed; I Love My Freedom, the team that runs the eponymous newsletter, has actually obtained an expanding checklist of Americans call info with a concealed e-mail collecting system including an internet of pro-Trump Facebook web pages.

Right- wing political leaders, companies as well as media electrical outlets have a background of dealing with unethical entities behind the scenes to earn money as well as press their programs. The Trump campaigns service with I Love My Freedom is no exemption.

I Love My Freedom (e-mail information multiplied by HuffPost).

By layout, its e-mails seem theyre sent out straight from Trump as well as his allies, though theyre in fact dispersed by means of [emailprotected] At all-time low, they birth please notes noting they were spent for by either the National Republican Senatorial Committee, its House equivalent, the McConnell Senate Committee, or the Trump Make America Great Again Committee (which is collectively run by the Republican National Committee as well as Trumps reelection campaign).

Renting out accessibility to collected e-mail listings is a typical as well as very profitable method worked out by traditional as well as liberal teams alike, commonly for political fundraising objectives. But points obtain morally dirty when e-mail representatives do not veterinarian their enrollers which can lead to e-mail receivers being flooded with ripoffs as well as scams, like the counterfeit cancer cells treatment. In this instance, nonetheless, the genuine inquiry is whether Trumps group troubled to veterinarian I Love My Freedom.

The campaign did not react to HuffPosts ask for remark.

I Love My Freedom, which makes up the newsletter as well as a conservative blog site called Trending Politics, belongs to Making Web LLC, a rare advertising company thats signed up in Minnesota to a 51- year-old male called Allan G. Ferretti.

Through the newsletter alone, I Love My Freedom has actually enhanced a list of aggressive rip-offs consisting of some that misleadingly link Trump, in spite of its negotiations with his campaign. Hours prior to dispersing a fundraising e-mail from the McConnell Senate Committee this month, I Love My Freedom discharged off a funded message advertising a breakthrough stem cell therapy which it baselessly suggested Trump is getting.

This has got Liberals jumping out of their seats, the e-mail checks out. President Trump is in perfect health how is it that hes so seemingly immune to old age? Well in recent years, billionaires like President Trump have increasingly turned to the power of Stem Cells.

Titled Trump Health Bombshell, the e-mail web links to a rambling item pitch that promotes $67 containers of stem cell tablets as the Holy Grail of aging backwards. These tablets make cells inside your body become physically younger, it asserts, without supplying a shred of clinical proof. I Love My Freedom has likewise spammed its customers with enrollers get-rich-quick plans consisting of a secret IRS loophole, as well as has actually routed them to video clips recommending elders ought to exchange their recommended medicines for tricksters supplements also advising that they can pass away if they do not.

Recent newsletter versions have actually circulated actual phony information, as well, installing advertisements camouflaged as write-ups that connect to internet sites stealthily copying genuine media electrical outlets.

I Love My Freedom e-newsletters have actually included misleading advertisements resulting in phony information websites copying genuine electrical outlets..

One such advertisement includes the message Royal Family Mourns As Tragedy Is Confirmed, along with a picture of Meghan Markle, the Duchess ofSussex Clicking on it causes a web site imitating U.S.A. Today that goes crazy regarding a skin care line, which it incorrectly asserts Markle released. Another, birthing the heading [BREAKING NEWS] Prayers Go Out to Oprah Winfrey, web links to a fraudulent information website marketing a Brain Booster supplement, which it brazenly states is in charge of Winfreys occupation success.

In enhancement to Trump, his oldest kid, McConnell as well as Gingrich, I Love My Freedom has actually likewise sent fundraising e-mails in behalf of previous White House press assistant Sarah Huckabee Sanders, House Minority Leader Kevin McCarthy (R-Calif), House Republican Whip Steve Scalise (R-La), previous United Nations Ambassador Nikki Haley,Rep Elise Stefanik (R-N.Y.),Rep David Joyce (R-Ohio), previous White House Deputy Chief of Staff Karl Rove as well as National Republican Congressional Committee Chairman TomEmmer

All were spent for by the NRCC, NRSC, McConnell Senate Committee or the Trump Make America Great AgainCommittee Only the NRCC reacted to an ask for remark.

We rented this list to prospect new donors. We do our best to vet each vendor, but similar to renting a car, it is impossible to know or control what every other renter does with a list they too are renting, spokesperson Chris Pack informed HuffPost.

We will not be using this vendor going forward.

I Love My Freedom constructed its cash-cow e-mail realm by spending virtually $2 million right into Facebook advertisements, which attract individuals in with clickbait surveys or pledges of free MAGA equipment, as well as result in web pages advising them to send their e-mail addresses. This immediately indications them as much as obtain the newsletter, in addition to its numerous funded messages.

The team likewise earns money by marketing Trump- themed product such as Make Liberals Cry Again hats, as well as organizing third-party advertisements on Trending Politics which was seen a million times last month alone, according to electronic analytics device ComparableWeb

I Love My Freedom did not accept HuffPosts ask for a meeting.

I Love My Freedom makes use of clickbait Facebook advertisements to gather individualss e-mails, after that subscribes them to its newsletter.

Ferretti released ilovemyfreedom.org in addition to the Facebook web page Trump for President Fan Club (currently President Donald Trump Fan Club, which has 1.6 million fans) in the summertime of 2015, as reporter April Glaser reported last loss in a write-up regarding I Love My Freedoms viral development on Facebook.

Its among greater than a lots preferred web pages the team runs to run its countless Facebook advertisements, consisting of Donald Trump Is My President, Donald Trump 2020 Voters, President Trump Has My Vote, Donald Trumps Americans, Team Trump Fan Club, The President Trump Fan Club, We Need Trump 2020 as well as President Trumps Patriot Army.

These web pages create a stream of hyper-partisan memes as well as Trending Politics post to their target market of millions. Boosted by Facebooks formula, the advertisements which largely target elders are in some cases seen thousands of countless times each.

This looks like an operation thats got a very highly engaged audience that would be a prime target for a lot of conservative politicians to try to raise grassroots money from, stated Michael Beckel, research study supervisor at the political reform team Issue One.

When you run a pro-Trump Facebook team with greater than a million participants, that can make your [email] checklist an appealing possession.

Trumps campaign has actually currently gathered a citizen e-mail checklist thats so big it leases it out to outdoors celebrations. So why would certainly his group wish to fundraise with I Love My Freedoms checklist particularly provided the teams historical connections to grifters as well as scam artist?

Its type of striking that the Trump campaign is making a financial investment in [I Love My Freedoms] checklist, kept in mindBeckel But a t completion of the day, he stated, much more e-mails still means more potential voters or donors for them.

Calling all HuffPost superfans!

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Donald Trump Is Using An Insanely Sketchy Newsletter To Find Campaign Donors - The Union Journal

Stem Cell Alopecia Treatment Market 2020 | Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2026 -…

By adminMarch 28, 2020Stem Cell Treatment

New Jersey, United States:The Stem Cell Alopecia Treatment Market is carefully researched in the report while largely concentrating on top players and their business tactics, geographical expansion, market segments, competitive landscape, manufacturing, and pricing and cost structures. Each section of the research study is specially prepared to explore key aspects of the Stem Cell Alopecia Treatment market. For instance, the market dynamics section digs deep into the drivers, restraints, trends, and opportunities of the Stem Cell Alopecia Treatment Market. With qualitative and quantitative analysis, we help you with thorough and comprehensive research on the Stem Cell Alopecia Treatment market. We have also focused on SWOT, PESTLE, and Porters Five Forces analyses of the Stem Cell Alopecia Treatment market.

Leading players of the Stem Cell Alopecia Treatment market are analyzed taking into account their market share, recent developments, new product launches, partnerships, mergers or acquisitions, and markets served. We also provide an exhaustive analysis of their product portfolios to explore the products and applications they concentrate on when operating in the Stem Cell Alopecia Treatment market. Furthermore, the report offers two separate market forecasts one for the production side and another for the consumption side of the Stem Cell Alopecia Treatment market. It also provides useful recommendations for new as well as established players of the Stem Cell Alopecia Treatment market.

Stem Cell Alopecia Treatment Market by Regional Segments:

The chapter on regional segmentation describes the regional aspects of the Stem Cell Alopecia Treatment market. This chapter explains the regulatory framework that is expected to affect the entire market. It illuminates the political scenario of the market and anticipates its impact on the market for Stem Cell Alopecia Treatment.

Analysts who have authored the report have segmented the market for Stem Cell Alopecia Treatment by product, application and region. All segments are the subject of extensive research, with a focus on CAGR, market size, growth potential, market share and other important factors. The segment study provided in the report will help players focus on the lucrative areas of the Stem Cell Alopecia Treatment market. The regional analysis will help the actors to strengthen their position in the most important regional markets. It shows unused growth opportunities in regional markets and how they can be used in the forecast period.

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Overview: In addition to an overview of the Stem Cell Alopecia Treatment market, this section provides an overview of the report to give an idea of the type and content of the study.

Market dynamics: Here the authors of the report discussed in detail the main drivers, restrictions, challenges, trends and opportunities in the market for Stem Cell Alopecia Treatment.

Product Segments: This part of the report shows the growth of the market for various types of products sold by the largest companies.

Application segments: The analysts who have authored the report have thoroughly evaluated the market potential of the key applications and identified the future opportunities they should create in the Stem Cell Alopecia Treatment.

Geographic Segments: Each regional market is carefully examined to understand its current and future growth scenarios.

Company Profiles: The top players in the Stem Cell Alopecia Treatment market are detailed in the report based on their market share, served market, products, applications, regional growth and other factors.

The report also includes specific sections on production and consumption analysis, key results, key suggestions and recommendations, and other issues. Overall, it offers a complete analysis and research study of the Stem Cell Alopecia Treatment market to help players ensure strong growth in the coming years.

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Canine Stem Cell Therapy Market Dynamics, Segments and Supply Demand 2029 – Packaging News 24

By adminMarch 28, 2020Stem Cell Treatment

Edible Insects Market Insights 2019, is a professional and in-depth study on the current state of the global Edible Insects industry with a focus on the Global market. The report provides key statistics on the market status of the Edible Insects manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry. Overall, the report provides an in-depth insight of2017 2024Edible Insects Marketcovering all important parameters.

The research report studies the Edible Insects Marketusing different methodologies and analyzes to provide accurate and in-depth information about the market. For a clearer understanding, it is divided into several parts to cover different aspects of the market. Each area is then elaborated to help the reader comprehend the growth potential of each region and its contribution to the global market. The researchers have used primary and secondary methodologies to collate the information in the report. They have also used the same data to generate the current market scenario. This report is aimed at guiding people towards an apprehensive, better, and clearer knowledge of the market.

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Canine Stem Cell Therapy Market Dynamics, Segments and Supply Demand 2029 - Packaging News 24

Pros and Cons of Stem Cell Research – ThoughtCo

By adminMarch 27, 2020Stell Cell Research

Debates over the ethics of embryonic stem cell research have divided scientists, politicians, and religious groups for years.

However, promising developments in other areas of stem cell research have led to solutions that help bypass these ethical barriers and win more support from those against embryonic stem cell research; the newer methods don't require the destruction of blastocysts.

Many parties continue to have strong opinions that trigger ongoing debates about stem cell research, and the following pros and cons provide a snapshot of some the points on each side of the issue.

The excitement about stem cell research is primarily due to the medical benefits in areas ofregenerative medicineand therapeutic cloning. Stem cells provide huge potential for finding treatments and cures to a vast array of medical issues:

Different diseasesincluding cancers, Alzheimer's, Parkinson's, and morecan be treated with stem cells by replacing damaged or diseased tissue. This can include neurons that might affect neurological diseases and even entire organs that need to be replaced.

There is endless potential for scientists to learn about human growth and cell development from studying stem cells. For example, by studying how stem cells develop into specific types of cells, scientists potentially could learn how to treat or prevent relevant ailments.

One of the areas of potential is embryonic treatment. This stage of pregnancy is when many birth defects or other potential issues begin. Studying embryonic stem cells possibly could lead to a better understanding of how embryos develop and maybe even lead to treatments that can identify and address potential problems.

Because the cells can replicate at a high rate, a limited number of initial cells eventually can grow into a much greater number to be studied or used in treatment.

Medical benefits such as regenerating organ tissue and therapeutic cell cloning

May hold the answer to curing various diseases, including Alzheimer's, certain cancers and Parkinson's

Research potential for human cell growth and development to treat a variety of ailments

Possibility of use for embryonic treatment

Requires only a small number of cells because of the fast replication rate

The difficulty of obtaining stem cells and the long period of growth required before use

Unproven treatments often come with high rejection rates

Cost can be prohibitive for many patients

Ethical controversy over use of stem cells from lab-fertilized human eggs

Additional ethical issues regarding the creation of human tissues in a lab, such as cloning

Stem cell research presents problems like any form of research, but most opposition to stem cell research is philosophical and theological, focusing on questions of whether we should be taking science this far:

It's not easy to obtain stem cells. Once harvested from an embryo, stem cells require several months of growth before they can be used. Obtaining adult stem cells, such as from bone marrow, can be painful.

As promising as the field is, stem cell treatments still are unproven, and they often have high rejection rates.

The cost also can be prohibitive for many patients, with a single treatment costing well into the thousands of dollars, as of 2018.

The use of embryonic stem cellsforresearchinvolves the destruction of blastocysts formed from laboratory-fertilized human eggs. For those who believe that life begins at conception, the blastocyst is a human life, and to destroy it is unacceptable and immoral.

A similar theological problem is an idea of creating living tissue in a laboratory and whether that represents humans taking on the role of God. This argument also applies to the potential for human cloning. For those who believe God created people, the prospect of people creating people is troublesome.

In 1998, the first published research paper on the topic reported that stem cells could be taken from human embryos. Subsequent research led to the ability to maintain undifferentiated stem cell lines (pluripotent cells) and techniques for differentiating them into cells specific to various tissues and organs.

The debates over the ethics of stem cell research began almost immediately in 1999, despite reports that stem cells cannot grow into complete organisms.

In 20002001, governments worldwide were beginning to draft proposals and guidelines to control stem cell research and the handling of embryonic tissues and reach universal policies. In 2001, the Canadian Institutes of Health Research (CIHR) drafted a list of recommendations for stem cell research. In the U.S., the Clinton administration drafted guidelines for stem cell research in 2000. Australia, Germany, the United Kingdom, and other countries followed suit and formulated their own policies.

Debates over the ethics of studying embryonic stem cells continued for nearly a decade until the use of adult-derived stem cellsknown as induced pluripotent stem cells (IPSCs)became more prevalent and alleviated those concerns.

In the U.S. since 2011, federal funds can be used to study embryonic stem cells, but such funding cannot be used to destroy an embryo.

Use of adult-derived stem cellsknown as induced pluripotent stem cells (IPSCs)from blood, cord blood, skin, and other tissues have been demonstrated as effective in treating different diseases in animal models. Umbilical cord-derived stem cells obtained from the cord blood also have been isolated and used for various experimental treatments. Another option is uniparental stem cells. Although these cell lines are shorter-lived than embryonic cell lines, uniparental stem cells hold vast potential if enough research money can be directed that way: pro-life advocates do not technically consider them individual living beings.

Two recent developments from stem cell research involve the heart and the blood it pumps. In 2016, researchers in Scotland began working on the possibility of generating red blood cells from stem cells in order to create a large supply of blood for transfusions. A few years earlier, researchers in England began working on polymers derived from bacteria that can be used to repair damaged heart tissue.

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Pros and Cons of Stem Cell Research - ThoughtCo

Stem cells: Therapy, controversy, and research

By adminMarch 27, 2020Stell Cell Research

The idea of a miracle cure and bodies healing themselves holds a particular fascination. Stem cell research brings regenerative medicine a step closer, but many of the ideas and concepts remain controversial. So what are stem cells, and why are they so important?

Stem cells are a type of cell that can develop into many other types of cell. Stem cells can also renew themselves by dividing, even after they have been inactive for a long time.

The human body requires many different types of cell to function, but it does not produce each cell type fully formed and ready to use. Instead, it produces stem cells that have a wide range of possible functions. However, stem cells need to become a specific cell type to be useful.

When a stem cell divides, the new cells may either become another stem cell or a specific cell, such as a blood cell, a brain cell, or a muscle cell.

Scientists call a stem cell an undifferentiated cell because it can become any cell. In contrast, a blood cell, for example, is a differentiated cell, because it is already a specific kind of cell.

In some tissues, stem cells play an essential role in regeneration, as they can divide easily to replace dead cells.

Scientists believe that knowing how stem cells work may lead to possible treatments for conditions, such as diabetes and heart disease.

For instance, if someones heart contains damaged tissue, doctors might be able to stimulate healthy tissue to grow by transplanting laboratory-grown stem cells into the persons heart. This could cause the heart tissue to renew itself.

Researchers on a small-scale study published in the Journal of Cardiovascular Translational Research tested this method.

The results showed a 40 percent reduction of the size of scarred heart tissue caused by heart attacks when doctors transplanted stem cells to the damaged area.

Doctors have always considered this kind of scarring permanent and untreatable.

However, this small study involved only 11 participants. This makes it difficult to tell whether the improvement in heart function resulted from the transplantation of stem cells or whether it was due to something else.

For example, all of the transplants took place while the individuals were undergoing heart bypass surgery, so it is possible that the improvement in heart function was due to the bypass rather than the stem cell treatment.

To investigate further, the researchers plan to do another study. This study will include a control group of people with heart failure who undergo bypass surgery but who do not receive the stem cell treatment.

Another investigation, published in Nature Communications in 2016, has suggested that stem cell therapies could be the basis of personalized diabetes treatment.

In mice and laboratory-grown cultures, researchers successfully produced insulin-secreting cells from stem cells derived from the skin of people with type 1 diabetes.

Jeffrey R. Millman, assistant professor of medicine and biomedical engineering at Washington University School of Medicine and first author, says:

In theory, if we could replace the damaged cells in these individuals with new pancreatic beta cells whose primary function is to store and release insulin to control blood glucose patients with type 1 diabetes wouldnt need insulin shots anymore.

Jeffrey R. Millman

Millman hopes that these stem cell-derived beta cells could be ready for research in humans within 3 to 5 years.

What were envisioning is an outpatient procedure in which some sort of device filled with the cells would be placed just beneath the skin, he said.

Stem cells could have vast potential in developing new therapies.

One way that scientists use stem cells at the moment is in developing and testing new drugs.

The type of stem cells that scientists commonly use for this purpose are called induced pluripotent stem cells.

These are cells that have already undergone differentiation, but which scientists have genetically reprogrammed using viruses, so they can divide and become any cell. In this way, they act like undifferentiated stem cells.

Scientists can grow differentiated cells from these pluripotent stem cells to resemble, for instance, cancer cells. Creating these cells means that scientists can use them to test anti-cancer drugs.

Researchers are already making a wide variety of cancer cells using this method. However, because they cannot yet create cells that mimic cancer cells in a controlled way, it is not always possible to replicate the results precisely.

In recent years, clinics have opened that provide stem cell treatments.

A 2016 study published in Cell Stem Cell counted 570 of these clinics in the United States alone. They offer stem cell-based therapies for disorders ranging from sports injuries to cancer.

However, stem cell therapies are still mostly theoretical rather than evidence-based.

Very few stem cell treatments have even reached the earliest phase of a clinical trial. Scientists are carrying out most of the current research in mice or a petri dish.

Despite this, the U.S. Food and Drug Administration (FDA) allow clinics to inject people with their own stem cells, as long as the cells are intended to perform only their normal function, according to Cell Stem Cell.

Scientists can harvest stem cells in different ways.

Embryonic stem cells come from an embryo that is just a few days old.

Scientists can extract adult stem cells from different types of tissue, including the brain, bone marrow, blood vessels, skeletal muscle, skin, teeth, the gut, the liver, among others.

Amniotic fluid contains stem cells. Many women opt for an amniocentesis test that checks for congenital disabilities before the child is born. If the doctor keeps the fluid, they could use it in the future to treat other conditions either during gestation or after birth.

Induced pluripotent stem cells (iPS cells) are cells that scientists can reprogram to act as stem cells, for use in regenerative medicine.

After collecting the stem cells, scientists usually store them in liquid nitrogen for future use.

Historically, the use of stem cells in medical research has been controversial.

This is because when the therapeutic use of stem cells first came to the publics attention in the late 1990s, scientists were deriving human stem cells from embryos.

Many people disagree with using human embryonic cells for medical research because extracting the stem means destroying the embryo.

This creates complex issues, as people have different beliefs about what constitutes the start of human life.

For some people, life starts when a baby is born, or when an embryo develops into a fetus. Others believe that human life begins at conception, so an embryo has the same moral status and rights as a human adult or child.

President George W. Bush had strong, pro-life religious views, and he banned funding for human stem cell research in 2001.

However, President Obamas administration allowed for a partial rolling back of these research restrictions.

However, by 2006, scientists had already started using pluripotent stem cells. Scientists do not derive these stem cells from embryonic stem cells. As a result, this technique does not have the same ethical concerns.

With this and other recent advances in stem cell technology, attitudes toward stem cell research are slowly beginning to change.

Stem cell research is helping scientists to understand how an organism develops from a single cell, and how healthy cells come to replace defective cells in people and animals.

Many severe medical conditions that occur in humans, such as cancer and congenital disabilities, happen because cells divide abnormally.

A better understanding of stem cells can provide insight into how these diseases arise and possible treatment options.

In June 2016, two researchers took second prize in the materials category of the United Kingdoms Royal Society of Chemistrys emerging technology competition for creating a synthetic biomaterial that stimulates stem cells native to a persons own teeth.

The researchers believe that this material will replace fillings, as the stem cells would prompt the damaged teeth to heal themselves.

Although much more research is necessary before stem cell therapies can become part of regular medical practice, the science around stem cells is developing all the time.

In almost every therapy area, doctors hope that stem cell technology will revolutionize therapeutic norms and introduce at least a new standard of personalized treatment, and maybe even self-healing bodies.

When that might happen, no one is quite ready to say.

Find out more here about stem cells, where they come from, and their possible uses.

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Stem cells: Therapy, controversy, and research

One upside of the coronavirus shutdown, maybe? Fewer voter initiatives – CALmatters

By adminMarch 27, 2020Stell Cell Research

In SummaryInitiative proponents have until the end of April to collect the signatures they need to put their ideas on the ballot and with millions of Californians staying home, some campaigns won't have time to collect enough signatures.

California voters may experience a small silver lining amid the coronavirus pandemic: a shorter November ballot, featuring fewer of the statewide propositions that often put voters in the middle of confusing industry fights.

Initiative proponents have until the end of April to collect the signatures they need to put their ideas on the ballot and with millions of Californians staying home, and practicing social distancing when they go out, it may be impossible for some campaigns to collect enough signatures in time.

People arent out in public, and those who are out in public arent inclined to approach a stranger, take a pen, and stand within 6 feet to put something on the ballot, said Brian Brokaw, a Democratic political consultant who has been involved in several potential ballot measures.

Normally presidential election years attract a slew of initiatives, as campaigns particularly those pushing liberal ideas seek approval from a larger and more diverse electorate. Though we wont know until July exactly how many propositions will be on the ballot, it appears likely that it will be a lot less than in 2016, when Californians voted on 17 statewide ballot measures. Political insiders estimate the final number for 2020 will be in the range of six to 10.

Thats good news for election officials, who could face lower costs for printing and mailing shorter ballots, and for voters who may find the decision-making easier when faced with fewer proposals, said Kim Alexander, president of the nonprofit California Voter Foundation.

Sometimes voting in California can feel like youre taking a test voters can be intimidated by the length and complexity of the ballot, she said. So it could help encourage voter participation if we have fewer complex initiatives sprouting out of special-interest fighting.

People arent out in public, and those who are out in public arent inclined to approach a stranger, take a pen, and stand within 6 feet to put something on the ballot.

So far four measures have qualified for the November ballot, one measure has submitted signatures that are being verified, and another eight have collected at least 25% of the necessary signatures. (Depending on what type of law an initiative would change, it needs either about 623,000 valid signatures or about 997,000 valid signatures.)

Several campaigns have stopped collecting signatures because of the coronavirus shutdown, including those pushing initiatives to allow sports betting, tax plastic packaging to fund environmental programs, continue funding stem cell research and expand Californias data privacy law.

None of them are officially calling it quits. Some may already have enough signatures to make it on the ballot, while others are hoping they can resume collecting signatures in time to get more.

Because the health and wellbeing of Californians is foremost, we paused paid signature gathering efforts for the time being, said Jacob Mejia, a spokesman for the Pechanga Indian tribe that is backing the measure to permit sports betting. Tribal leadership remains committed to bringing this proposal to voters in November and are monitoring developments closely and assessing all options.

But the odds of getting back on the street with pens and clipboards any time soon seem slim, as Gov. Gavin Newsom has said the order to stay home to curb the spread of coronavirus may last two to three months.

Everything is on hold until its safe, said Dan Newman, a spokesman for the plastic recycling measure.

He said the campaign will try to get on the 2022 ballot if it cant resume gathering signatures very soon.

Newsom said this week that companies that are paid to gather signatures for ballot initiatives have asked him to extend the deadlines for submitting signatures so they can have more time to qualify for the November ballot. He was noncommittal, saying only that the question is one of many things hes processing in response to the pandemic.

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One upside of the coronavirus shutdown, maybe? Fewer voter initiatives - CALmatters

SENECA BIOPHARMA : MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (form 10-K) – marketscreener.com

By adminMarch 27, 2020Stell Cell Research

Our Management's Discussion and Analysis of Financial Condition and Results ofOperations or MD&A, is provided in addition to the accompanying financialstatements and notes to assist readers in understanding our results ofoperations, financial condition and cash flows. Our MD&A is organized asfollows:

Trends & Outlook - Discussion of what we view as the overall trends

important to understanding the assumptions and judgments incorporated in

our reported financial results and forecasts.

Results of Operations- Analysis of our financial results comparing the:

(i) year ended December 31, 2019 to the year ended December 31, 2018.

Liquidity and Capital Resources-Analysis of cash flows and discussion of

Our patented technology platform has three core components:

1. Over 300 lines of human, regionally specific neural stem cells, some of

which have the potential to be used to treat serious or life-threatening

diseases through direct transplantation into the central nervous system;

2. Proprietary screening capability - our ability to generate human neural

stem cell lines provides a platform for chemical screening and discovery of

3. Small molecules that resulted from Seneca's neurogenesis screening platform

We generated no revenues from the sale of our proposed therapies for any of theperiods presented.

We have historically generated minimal revenue from the licensing of ourintellectual property to third parties as well as payments under a settlementagreement.

Research and Development Expenses

We have a wholly owned subsidiary in the People's Republic of China thatprimarily oversees our current clinical trial to treat motor deficits due toischemic stroke.

General and Administrative Expenses

Critical Accounting Policies

Comparison of Our Results of Operations for the Years Ended December 31, 2019and 2018

Operating Expenses

Operating expenses for 2019 and 2018 were as follows:

Research and Development Expenses

General and Administrative Expenses

Other income (expense)

Other income, net in 2018 consisted of approximately $3,269,000 of non-cashgains related to the change in the fair value of our liability classified stockpurchase warrants and $79,000 of interest income.

Cash Flows - 2019 compared to 2018

Net Cash Used in Operating Activities

Net Cash Used in Investing Activities

There were no investing activities in the year ended December 31, 2019.

For the year ended December 31, 2018 cash provided by investing activities wascomprised primarily of proceeds from the maturity of our short-term investments.

Net Cash Provided by Financing Activities

For the year ended December 31, 2018, cash provided by financing activitiesconsisted primarily of approximately $1.8 million of net proceeds from ourOctober financing transaction.

Future Liquidity and Needs

Off-balance Sheet Arrangements

None.

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SENECA BIOPHARMA : MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (form 10-K) - marketscreener.com