Gruber brings a wealth of clinical and laboratory experience from St. Jude Children's Research Hospital, where she worked for more than a decade, most recently as an Associate Member of the Molecular Oncology Division in the Oncology Department. While at St. Jude, she became a nationally and internationally recognized leader and physician-scientist who ran a research laboratory in addition to national clinical trials.

"I am thrilled to welcome Dr. Gruber to Stanford Children's Health," said Paul King, president and CEO of Stanford Children's Health. "On the heels of opening our new inpatient cancer centerin 2019, Dr. Gruber's leadership as a remarkably accomplished and collaborative physician-scientist will further enhance Stanford Children's Health's ability to offer preeminent, innovative treatment for pediatric cancer, blood diseases, and stem cell transplantation."

Gruber's research focuses on high-risk leukemia and acute megakaryoblastic leukemia (AMKL). Research in her lab at St. Jude led to the identification of CBFA2T3-GLIS2, a novel fusion gene that confers a poor prognosis in pediatric AMKL and a detailed view of the genomic landscape in MLLr leukemia. Her lab also identified bortezomib and vorinostat as active agents in MLLr leukemia with a novel mechanism of action. These data formed the preclinical basis for the multi-institutional clinical trial "Total Therapy for Infants with Acute Lymphoblastic Leukemia," for which patients at Lucile Packard Children's Hospital Stanford were recruited.

"We are tremendously excited about Tanja's arrival. She will be a transformative leader for the Division of Pediatric Hematology, Oncology, and will also play a pivotal role as the Stanford Cancer Institute's new Associate Director for Pediatric Cancer," said Steven Artandi, MD, PhD, director of the Stanford Cancer Institute. "Her expertise as both a laboratory scientist and clinical trialist will bring added strength to our cancer drug discovery efforts, and her background in immunology will enable us to explore new synergies between our adult and pediatric efforts."

"Stanford is an incredibly inspiring place, and I look forward to working with all the physicians and scientists here to develop new treatment approaches and bring them to patients," Gruber said. "The passion for providing excellent patient care rooted in cutting-edge science is clear, and the opportunity to lead a group that is so committed to advancing the field of pediatric cancer and blood diseases is very exciting."

Gruber graduated from the University of Southern California with an MD in Medicine and PhD in Immunology. She completed residency and a fellowship in hematology and oncology at Children's Hospital Los Angeles prior to being recruited by St. Jude.

Media ContactKate DeTrempe [emailprotected] (650) 485-9487

About Stanford Children's HealthStanford Children's Health, with Lucile Packard Children's Hospital Stanfordat its center, is the Bay Area's largest health care system exclusively dedicated to children and expectant mothers. Our network of care includes more than 65 locationsacross Northern California and more than 85 locations in the U.S. Western region. As part of Stanford Medicine, a leading academic health system that also includes Stanford Health Care and Stanford University School of Medicine, we are cultivating the next generation of medical professionals and are at the forefront of scientific research to improve children's health outcomes around the world. We are a nonprofit organization committed to supporting the community through meaningful outreach programs and services and providing necessary medical care to families, regardless of their ability to pay. Discover more at stanfordchildrens.org.

SOURCE Stanford Childrens Health

http://www.stanfordchildrens.org/

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Stanford Children's Health Appoints New Chief of Pediatric Hematology, Oncology, Stem Cell Transplantation, and Regenerative Medicine - PRNewswire